alpha-ethyl, alpha-methyl-thiobutyrolactone has been researched along with 4-butyrolactone in 10 studies
| Studies (alpha-ethyl, alpha-methyl-thiobutyrolactone) | Trials (alpha-ethyl, alpha-methyl-thiobutyrolactone) | Recent Studies (post-2010) (alpha-ethyl, alpha-methyl-thiobutyrolactone) | Studies (4-butyrolactone) | Trials (4-butyrolactone) | Recent Studies (post-2010) (4-butyrolactone) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 4,456 | 78 | 1,823 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Covey, DF; Ferrendelli, JA; Holland, KD; Rothman, SM; Yoon, KW | 1 |
| Covey, DF; Ferrendelli, JA; Holland, KD; Rothman, SM | 1 |
| Baker, K; Clifford, DB; Covey, DF; Yang, J; Zorumski, CF | 1 |
| Covey, DF; Ferrendelli, JA; Levine, JA; Naritoku, DK | 1 |
| Hauhart, RE; Thurston, JH | 1 |
| Bolos-Sy, AM; Covey, DF; Ferrendelli, JA; Mathews, GC; Rothman, SM | 1 |
| Covey, DF; Ferrendelli, JA; Gross, RA | 1 |
| Covey, DF; Ferrendelli, JA; Krause, JE; Rothman, SM; Tucker, JB; Weiss, DS; White, G; Williams, KL | 1 |
| Covey, DF; de la Cruz, MA; Hill, MW; Rothman, SM | 1 |
| Bracamontes, J; Covey, DF; Steinbach, JH; Yu, L; Zhang, P | 1 |
10 other study(ies) available for alpha-ethyl, alpha-methyl-thiobutyrolactone and 4-butyrolactone
| Article | Year |
|---|---|
Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist.
Topics: 4-Butyrolactone; Animals; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Rats; Receptors, GABA-A | 1991 |
Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons.
Topics: 4-Butyrolactone; Animals; Cells, Cultured; Electrophysiology; Furans; gamma-Aminobutyric Acid; Hippocampus; Lactones; Neurons; Picrotoxin; Receptors, Drug; Succinimides | 1990 |
Alpha-substituted thiobutyrolactones potentiate GABA currents in voltage-clamped chick spinal cord neurons.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cells, Cultured; Chick Embryo; Diazepam; Furans; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Phenobarbital; Picrotoxin; Spinal Cord | 1988 |
Effects of anticonvulsant and convulsant gamma-butyrolactones and thiobutyrolactones on GABA-mediated chloride uptake.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cerebral Cortex; Chlorides; Convulsants; Female; Furans; gamma-Aminobutyric Acid; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sesterterpenes; Structure-Activity Relationship | 1987 |
Comparative effects of valproate and the new experimental anticonvulsant drug alpha-ethyl-alpha-methyl-thiobutyrolactone on selected metabolite levels in the plasma, livers, and brains of infant mice.
Topics: 3-Hydroxybutyric Acid; 4-Butyrolactone; Amino Acids; Animals; Animals, Suckling; Anticonvulsants; Blood Glucose; Brain Chemistry; Carnitine; Coenzyme A; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Hydroxybutyrates; Liver; Mice; Valproic Acid | 1996 |
Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Chlordiazepoxide; Chlorine; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Patch-Clamp Techniques; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Transfection | 1996 |
Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones.
Topics: 4-Butyrolactone; Animals; Animals, Newborn; Anticonvulsants; Calcium Channels; Cells, Cultured; Convulsants; Ethosuximide; Evoked Potentials; Ganglia, Spinal; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 1997 |
Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site.
Topics: 4-Butyrolactone; Animals; Chlordiazepoxide; Female; Flumazenil; gamma-Aminobutyric Acid; Lactones; Phenobarbital; Picrotoxin; Receptors, GABA-A; Xenopus laevis | 1997 |
Effects of anticonvulsant lactams on in vitro seizures in the hippocampal slice preparation.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Calcium Channel Blockers; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Lactams; Mice; Phenytoin; Piperidines; Potassium Channel Blockers; Receptors, GABA-A; Seizures; Sodium Channel Blockers; Synaptic Transmission | 1999 |
Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region.
Topics: 4-Butyrolactone; Amino Acid Sequence; Amino Acids; Animals; Anticonvulsants; Humans; Membrane Proteins; Molecular Sequence Data; Mutation; Oocytes; Picrotoxin; Rats; Receptors, Glycine; Recombinant Proteins; Sequence Homology, Amino Acid; Sesterterpenes; Transfection; Xenopus | 2000 |