alpha-ergocryptine has been researched along with dihydroergotamine in 4 studies
| Studies (alpha-ergocryptine) | Trials (alpha-ergocryptine) | Recent Studies (post-2010) (alpha-ergocryptine) | Studies (dihydroergotamine) | Trials (dihydroergotamine) | Recent Studies (post-2010) (dihydroergotamine) |
|---|---|---|---|---|---|
| 74 | 1 | 8 | 1,450 | 241 | 116 |
| Protein | Taxonomy | alpha-ergocryptine (IC50) | dihydroergotamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.09 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 3.9996 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.001 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0089 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0039 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.01 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0007 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.395 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.029 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.008 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.09 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0007 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0053 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0068 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.0032 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 2.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boess, FG; Monsma, FJ; Sleight, AJ | 1 |
| Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K | 1 |
| Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
| Delaforge, M; Mansuy, D; Peyronneau, MA; Renaud, JP; Riviere, R | 1 |
4 other study(ies) available for alpha-ergocryptine and dihydroergotamine
| Article | Year |
|---|---|
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1998 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine | 2002 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine.
Topics: Animals; Bromocriptine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; Dihydroergotamine; Ergolines; Humans; Hydroxylation; Isoenzymes; Lysergic Acid; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Peptides; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 1994 |