alpha-ergocryptine has been researched along with bromocriptine in 12 studies
| Studies (alpha-ergocryptine) | Trials (alpha-ergocryptine) | Recent Studies (post-2010) (alpha-ergocryptine) | Studies (bromocriptine) | Trials (bromocriptine) | Recent Studies (post-2010) (bromocriptine) |
|---|---|---|---|---|---|
| 74 | 1 | 8 | 7,121 | 727 | 499 |
| Protein | Taxonomy | alpha-ergocryptine (IC50) | bromocriptine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.532 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 2.4 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2.4996 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.015 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0016 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 2.281 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.035 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.52 | |
| D | Rattus norvegicus (Norway rat) | 0.0279 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0056 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.514 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.889 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.514 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.514 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.03 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.036 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.532 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.0056 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0006 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0083 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.022 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0279 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boess, FG; Monsma, FJ; Sleight, AJ | 1 |
| Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K | 1 |
| Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
| Vesely, DL | 1 |
| Kolena, J; Seböková, E | 1 |
| Maurer, RA | 1 |
| Harrison, DJ; McNeilly, AS; Russell, JA | 1 |
| Aranyi, A; Bihari, M; Brlik, J; Csehi, A; Kassai, A; Szántay, C | 1 |
| Delaforge, M; Mansuy, D; Peyronneau, MA; Renaud, JP; Riviere, R | 1 |
| Casy, AF | 2 |
| Larson, BT; Rowell, PP | 1 |
12 other study(ies) available for alpha-ergocryptine and bromocriptine
| Article | Year |
|---|---|
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1998 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine | 2002 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
Bromocriptine enhances guanylate cyclase activity.
Topics: Animals; Bromocriptine; Dopamine; Dose-Response Relationship, Drug; Ergolines; Female; Guanylate Cyclase; Kinetics; Ovary; Pituitary Gland; Rats; Rats, Inbred Strains | 1981 |
Hormonal regulation of testicular LH/hCG receptors in rat.
Topics: Animals; Bromocriptine; Chorionic Gonadotropin; Ergolines; Estradiol; Gonadotropins, Equine; Hormones; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, LH; Testis; Testosterone | 1983 |
Dopaminergic inhibition of prolactin synthesis and prolactin messenger RNA accumulation in cultured pituitary cells.
Topics: Animals; Bromocriptine; DNA; Dopamine; Epinephrine; Ergolines; Female; Kinetics; Norepinephrine; Nucleic Acid Hybridization; Pituitary Gland; Prolactin; Protein Biosynthesis; Rats; RNA, Messenger | 1980 |
Bromocriptine and alpha-ergocryptine do not inhibit oxytocin secretion in the lactating rat.
Topics: Animals; Bromocriptine; Ergolines; Female; Lactation; Oxytocin; Pregnancy; Prolactin; Rats; Secretory Rate | 1981 |
Structural elucidation of two novel ergot alkaloid impurities in alpha-ergokryptine and bromokryptine.
Topics: Bromocriptine; Chromatography, High Pressure Liquid; Drug Contamination; Ergolines; Ergot Alkaloids; Magnetic Resonance Spectroscopy; Molecular Structure | 1994 |
High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine.
Topics: Animals; Bromocriptine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; Dihydroergotamine; Ergolines; Humans; Hydroxylation; Isoenzymes; Lysergic Acid; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Peptides; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 1994 |
Rapid identification of ergot derivatives by 1H-NMR spectroscopy.
Topics: Bromocriptine; Ergolines; Ergotamine; Magnetic Resonance Spectroscopy; Reference Standards; Stereoisomerism | 1994 |
Mass spectrometry as an aid to the identification of ergots and dihydroergots: comparison of hard and soft ionization techniques.
Topics: Bromocriptine; Ergolines; Ergotamine; Ergotamines; Molecular Weight; Spectrometry, Mass, Fast Atom Bombardment | 1994 |
Ergocryptine and other ergot alkaloids stimulate the release of [3H]dopamine from rat striatal synaptosomes.
Topics: Animals; Bromocriptine; Corpus Striatum; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Ergolines; Ergonovine; Ergotamine; Male; Rats; Rats, Sprague-Dawley; Synaptosomes | 1999 |