alpha-cyclodextrin and decanoic-acid

alpha-cyclodextrin has been researched along with decanoic-acid* in 1 studies

Other Studies

1 other study(ies) available for alpha-cyclodextrin and decanoic-acid

ArticleYear
[Effect of inclusion complexation of decanoic acid with alpha-cyclodextrin on rectal absorption of cefmetazole sodium suppository in rabbits].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1991, Volume: 111, Issue:1

    Inclusion complex of decanoic acid (DA) with alpha-cyclodextrin (alpha-CyD) was prepared as an additive of cefmetazole sodium (CMZ) suppository and rectally administered to rabbits. The resulting complexation was examined by the phase solubility method, differential scanning calorimetry (DSC) and X-ray diffractometry. Plasma concentration and AUC of CMZ after rectal administration of a suppository containing DA/alpha-CyD complex to rabbits increased more significantly than those with none additive.

    Topics: Adjuvants, Pharmaceutic; alpha-Cyclodextrins; Animals; Cefmetazole; Cyclodextrins; Decanoic Acids; Drug Combinations; Intestinal Absorption; Rabbits; Rectum; Stimulation, Chemical; Suppositories

1991