alpha-conhydrine and piperidine

alpha-conhydrine has been researched along with piperidine* in 2 studies

Other Studies

2 other study(ies) available for alpha-conhydrine and piperidine

ArticleYear
Highly enantioselective catalytic dynamic resolution of N-Boc-2-lithiopiperidine: synthesis of (R)-(+)-N-Boc-pipecolic acid, (S)-(-)-coniine, (S)-(+)-pelletierine, (+)-beta-conhydrine, and (S)-(-)-ropivacaine and formal synthesis of (-)-lasubine II and (+
    Journal of the American Chemical Society, 2010, Sep-08, Volume: 132, Issue:35

    The catalytic dynamic resolution (CDR) of rac-2-lithio-N-Boc-piperidine using chiral ligand 8 or its diastereomer 9 in the presence of TMEDA has led to the highly enantioselective syntheses of both enantiomers of 2-substituted piperidines using a wide range of electrophiles. The CDR has been applied to the synthesis of (R)- and (S)-pipecolic acid derivatives, (+)-beta-conhydrine, (S)-(+)-pelletierine, and (S)-(-)-ropivacaine and the formal synthesis of (-)-lasubine II and (+)-cermizine C.

    Topics: Alkaloids; Amides; Catalysis; Heterocyclic Compounds, 2-Ring; Lithium; Molecular Conformation; Organometallic Compounds; Pipecolic Acids; Piperidines; Quinolizines; Ropivacaine; Stereoisomerism; Thermodynamics

2010
Ether-directed, stereoselective aza-Claisen rearrangements: synthesis of the piperidine alkaloid, alpha-conhydrine.
    Organic letters, 2007, Apr-12, Volume: 9, Issue:8

    [reaction: see text] A new approach for the stereoselective synthesis of the piperidine alkaloid (+)-alpha-conhydrine and its pyrrolidine derivative has been developed using a palladium(II)-catalyzed, MOM-ether-directed aza-Claisen rearrangement and ring-closing metathesis to effect the key steps.

    Topics: Alkaloids; Aza Compounds; Ether; Molecular Structure; Piperidines; Propanols; Pyrrolidines; Stereoisomerism

2007