alpha-chymotrypsin has been researched along with dihydrolipoic-acid* in 1 studies
1 other study(ies) available for alpha-chymotrypsin and dihydrolipoic-acid
| Article | Year |
|---|---|
Thermodynamics, Kinetics and Mechanisms of Noncompetitive Allosteric Inhibition of Chymotrypsin by Dihydrolipoic Acid-Coated Gold Nanoclusters.
Enzymes are an important class of biomacromolecules which catalyze many metabolic processes in living systems. Nanomaterials can be synthesized with tailored sizes as well as desired surface modifications, thus acting as promising enzyme regulators. Fluorescent gold nanoclusters (AuNCs) are a representative class of ultrasmall nanoparticles (USNPs) with sizes of ∼2 nm, smaller than most of proteins including enzymes. In this work, we chose α-chymotrypsin (ChT) and AuNCs as the model system. Activity assays and inhibition kinetics studies showed that dihydrolipoic acid (DHLA)-coated AuNCs (DHLA-AuNCs) had a high inhibitory potency ( Topics: Chymotrypsin; Gold; Kinetics; Metal Nanoparticles; Thermodynamics; Thioctic Acid | 2020 |