alpha-chymotrypsin and beta-(5-hydroxy-2-pyridyl)alanine

alpha-chymotrypsin has been researched along with beta-(5-hydroxy-2-pyridyl)alanine* in 1 studies

Other Studies

1 other study(ies) available for alpha-chymotrypsin and beta-(5-hydroxy-2-pyridyl)alanine

Article	Year
Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives. Amino acids, 2012, Volume: 42, Issue:4 Enantiomerically pure 2-, 3- or 4-pyridylalanine (pya) and 2-azatyrosine (azatyr) are known to present various biological activities. After incorporation into appropriate peptide sequences, these heterocyclic non natural α-amino acids could behave as new substrates or inhibitors of elastase from Pseudomonas aeruginosa. This enzyme is known to be involved in nosocomial infections and infections related to the cystic fibrosis disease. New efficient chemoenzymatic preparations of those compounds using α-chymotrypsin (α-CT) are presented. Topics: Alanine; Chymotrypsin; Enzyme Inhibitors; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship	2012

Article

Year

Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives.

Amino acids, 2012, Volume: 42, Issue:4

Enantiomerically pure 2-, 3- or 4-pyridylalanine (pya) and 2-azatyrosine (azatyr) are known to present various biological activities. After incorporation into appropriate peptide sequences, these heterocyclic non natural α-amino acids could behave as new substrates or inhibitors of elastase from Pseudomonas aeruginosa. This enzyme is known to be involved in nosocomial infections and infections related to the cystic fibrosis disease. New efficient chemoenzymatic preparations of those compounds using α-chymotrypsin (α-CT) are presented.

Topics: Alanine; Chymotrypsin; Enzyme Inhibitors; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

2012