alpha-chymotrypsin has been researched along with 1-methylpyridinium* in 1 studies
1 other study(ies) available for alpha-chymotrypsin and 1-methylpyridinium
Article | Year |
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Isolation of a crystalline A14-(N-methylpyridinium) derivative of bovine insulin.
Reaction of insulin with 2-chloro- or 2-iodo-N-methylpyridinium iodide affords, amongst others, an insulin analogue modified at tha A14-tyrosine residue. Degradative procedures which pinpoint the exact position of modification are described. Highest yields of the derivative are obtained using the 2-iodo-N-methylpyridinium iodide as reagent. In the mouse convulsion assay this derivative retains 72% of its activity. Topics: Amino Acids; Animals; Biological Assay; Cattle; Chymotrypsin; Crystallization; Insulin; Macromolecular Substances; Protein Binding; Pyridinium Compounds; Tyrosine | 1979 |