Page last updated: 2024-08-18

alpha-chlorohydrin and glycidol

alpha-chlorohydrin has been researched along with glycidol in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.13)29.6817
2010's14 (43.75)24.3611
2020's17 (53.13)2.80

Authors

AuthorsStudies
El Ramy, R; Lezmi, S; Ould Elhkim, M; Poul, JM1
Abraham, K; Appel, KE; Bakhiya, N; Gürtler, R; Lampen, A1
Chiodini, A; Craft, BD; Garst, J; Granvogl, M1
Begley, TH; Diachenko, GW; MacMahon, S1
Abe, K; Egawa, Y; Ikuta, K; Kido, H; Kitta, T; Koyama, K; Miyashita, T; Miyazaki, K; Nezu, T; Nohara, H; Sano, T; Takahashi, Y; Watanabe, Y; Yada, H; Yamazaki, K1
Akagi, J; Cho, YM; Fujiwara, S; Nishikawa, A; Ochiai, R; Ogawa, K; Onami, S; Toyoda, T; Tsujino, K1
Drouard-Pascarel, V; Janvion, P; Marc, C; Rétho, C; Saltron, F1
Alpertunga, B; Ozden, S; Senyildiz, M1
Abraham, K; Andres, S; Bakhiya, N; Buhrke, T; Frenzel, F; Lampen, A; Monien, B; Schäfer, B; Schultrich, K1
Koyama, K; Miyazaki, K1
Fritsche, J; Karl, H; Merkle, S; Ostermeyer, U; Rohn, S1
Chirtel, S; Flannery, B; Kim, G; Leigh, J; MacMahon, S; Smegal, D; Spungen, JH1
Inagaki, R; Ito, F; Masuda, S; Shimamura, Y1
Chen, D; Chen, X; Jia, W; Mao, L; Miao, H; Ren, Y; Wu, D; Zhang, Y1
Abd Razak, RA; Abdul Hammid, AN; Ahmad Tarmizi, AH; Ismail, IS; Kuntom, A; Sanny, M1
Beekman, JK; Grassi, K; MacMahon, S1
Khor, YP; Lai, OM; Liu, Y; Nehdi, IA; Sim, BI; Tan, CP; Wang, Y; Yeoh, CB1
Sadowska-Rociek, A1
Abraham, K; Hielscher, J; Kuhlmann, J; Monien, BH1
Chen, HL; Chen, RJ; Chiou, YY; Huang, KC; Lee, CC; Li, CI; Liu, CS; Liu, PW1
Ahmad Tarmizi, AH; Md Sikin, A; Shaari, NA1
Haixia, S; Jiang, L; Jing, Z; Lei, Z; Lili, X; Ling, Y; Pingping, Z; Yan, S; Yanxu, Z; Yibaina, W1
Garrido Frenich, A; Hidalgo-Ruiz, JL; Martínez Vidal, JL; Romero-González, R1
Fan, D; Tao, M; Wang, M; Wang, R; Zhao, Y; Zhu, Y1
Kara, M; Margina, D; Mendil, AS; Özkaraca, M; Sevim, Ç; Tsatsakis, A; Ulaş, N1
Jia, W; Jiao, J; Liu, X; Shen, X; Wan, X; Wu, F; Zhang, Y; Zheng, W; Zhuang, P1
Chen, D; Chen, X; Jia, W; Mao, L; Miao, H; Ren, Y; Wan, X; Wang, Q; Zhang, Y; Zhuang, P1
Abraham, K; Monien, BH1
Andrade, SS; Corbi, PP; Costa, MC; Maximo, GJ; Meirelles, AJA; Sampaio, KA1
Becalski, A; Chen, F; Liu, Y; Rawn, DFK; Schneider, JF; Zhao, T1
Jia, W; Jiang, J; Jiao, J; Ke, X; Li, Y; Wan, X; Zhang, L; Zhang, Y1
Dall'Asta, C; Mihalache, OA1

Reviews

3 review(s) available for alpha-chlorohydrin and glycidol

ArticleYear
Toxicological assessment of 3-chloropropane-1,2-diol and glycidol fatty acid esters in food.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:4

    Topics: alpha-Chlorohydrin; Animals; Biotransformation; Carcinogens; Epoxy Compounds; Esters; Fatty Acids; Female; Food Contamination; Humans; Infertility, Male; Male; Mutagens; Neoplasms; Plant Oils; Propanols; Renal Insufficiency; Risk Assessment

2011
Fatty acid esters of monochloropropanediol (MCPD) and glycidol in refined edible oils.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2013, Volume: 30, Issue:1

    Topics: alpha-Chlorohydrin; Dietary Fats, Unsaturated; Epoxy Compounds; Esters; Fatty Acids; Food Analysis; Food Contamination; Propanols

2013
[Heat-induced contaminants in foodstuffs : Acrylamide, furan, and fatty acid esters of monochloropropanediols and glycidol].
    Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 2017, Volume: 60, Issue:7

    Topics: Acrylamide; alpha-Chlorohydrin; Carcinogens; Computer Simulation; Cooking; Epoxy Compounds; Food Contamination; Furans; Heating; Propanols; Risk Assessment

2017

Trials

1 trial(s) available for alpha-chlorohydrin and glycidol

ArticleYear
Urinary Excretion of 2/3-Monochloropropanediol (2/3-MCPD) and 2,3-Dihydroxypropylmercapturic Acid (DHPMA) after a Single High dose of Fatty Acid Esters of 2/3-MCPD and Glycidol: A Controlled Exposure Study in Humans.
    Molecular nutrition & food research, 2021, Volume: 65, Issue:4

    Topics: Adult; alpha-Chlorohydrin; Corylus; Creatinine; Epoxy Compounds; Esters; Female; Glycerol; Humans; Male; Middle Aged; Palm Oil; Propanols; Tandem Mass Spectrometry

2021

Other Studies

28 other study(ies) available for alpha-chlorohydrin and glycidol

ArticleYear
Evaluation of the genotoxic potential of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites, glycidol and beta-chlorolactic acid, using the single cell gel/comet assay.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:1

    Topics: Administration, Oral; alpha-Chlorohydrin; Animals; Bone Marrow Cells; Carcinogens; CHO Cells; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Glycerol; Kidney; Lactic Acid; Leukocytes; Liver; Male; Mutagens; Propanols; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Testis

2007
Occurrence of 3-MCPD and glycidyl esters in edible oils in the United States.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2013, Volume: 30, Issue:12

    Topics: alpha-Chlorohydrin; Carcinogens; Chromatography, High Pressure Liquid; Epoxy Compounds; Esterification; Fatty Acids; Food Contamination; Food Handling; Glycerol; Hot Temperature; Limit of Detection; Maryland; Molecular Structure; Mutagens; Palm Oil; Plant Oils; Propanols; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; United States

2013
Optimization of an Indirect Enzymatic Method for the Simultaneous Analysis of 3-MCPD, 2-MCPD, and Glycidyl Esters in Edible Oils.
    Journal of oleo science, 2015, Volume: 64, Issue:10

    Topics: alpha-Chlorohydrin; Candida; Enzyme Assays; Epoxy Compounds; Esters; Feasibility Studies; Gas Chromatography-Mass Spectrometry; Glycerol; Halogenation; Lipase; Olive Oil; Palm Oil; Plant Oils; Propanols; Temperature

2015
Orally administered glycidol and its fatty acid esters as well as 3-MCPD fatty acid esters are metabolized to 3-MCPD in the F344 rat.
    Regulatory toxicology and pharmacology : RTP, 2015, Volume: 73, Issue:3

    Topics: Administration, Oral; alpha-Chlorohydrin; Animals; Biotransformation; Cecum; Duodenum; Epoxy Compounds; Esters; Fatty Acids; Gastric Mucosa; Hydrolysis; Male; Propanols; Rats, Inbred F344

2015
Determination of 3-Monochloropropane-1,2-diol and 2-Monochloropropane-1,3-diol (MCPD) Esters and Glycidyl Esters by Microwave Extraction in Different Foodstuffs.
    Journal of agricultural and food chemistry, 2016, Jun-01, Volume: 64, Issue:21

    Topics: alpha-Chlorohydrin; Chemical Fractionation; Epoxy Compounds; Esters; Food Contamination; Gas Chromatography-Mass Spectrometry; Glycerol; Infant Formula; Microwaves; Propanols

2016
DNA methylation analysis in rat kidney epithelial cells exposed to 3-MCPD and glycidol.
    Drug and chemical toxicology, 2017, Volume: 40, Issue:4

    Topics: alpha-Chlorohydrin; Animals; Carcinogens; Cell Line; Cell Survival; Chemosterilants; CpG Islands; DNA Methylation; Epigenesis, Genetic; Epoxy Compounds; Gene Expression Regulation; Genes, myc; Inhibitory Concentration 50; Kidney Tubules; Promoter Regions, Genetic; Propanols; Rats; Tumor Suppressor Proteins

2017
An Improved Enzymatic Indirect Method for Simultaneous Determinations of 3-MCPD Esters and Glycidyl Esters in Fish Oils.
    Journal of oleo science, 2017, Oct-01, Volume: 66, Issue:10

    Topics: alpha-Chlorohydrin; Bromides; Burkholderia; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enzyme Assays; Epoxy Compounds; Esters; Fish Oils; Hydrolysis; Lipase; Propanols; Sodium Compounds

2017
Mitigation strategies for ester bound 2-/3-MCPD and esterified glycidol in pre-fried breaded and frozen fish products.
    Food chemistry, 2018, Apr-15, Volume: 245

    Topics: alpha-Chlorohydrin; Animals; Color; Cooking; Epoxy Compounds; Esters; Fatty Acids; Fish Products; Glycerol; Oils; Propanols; Temperature

2018
Estimated US infant exposures to 3-MCPD esters and glycidyl esters from consumption of infant formula.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2018, Volume: 35, Issue:6

    Topics: alpha-Chlorohydrin; Epoxy Compounds; Esters; Food Contamination; Humans; Infant; Infant Formula; Infant, Newborn; Propanols; United States

2018
Effect of chloride on the formation of 3-monochloro-1,2-propanediol fatty acid diesters and glycidol fatty acid esters in fish, meats and acylglycerols during heating.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2019, Volume: 36, Issue:2

    Topics: alpha-Chlorohydrin; Animals; Chlorides; Epoxy Compounds; Esters; Fatty Acids; Fishes; Food Contamination; Glycerides; Heating; Meat; Propanols

2019
Metabolomics-based biomarker analysis of dihydroxypropyl mercapturic acid isomers from 3-monochloropropane-1,2-diol and glycidol for evaluation of toxicokinetics in rats and daily internal exposure in humans.
    Talanta, 2019, Nov-01, Volume: 204

    Topics: Acetylcysteine; Adult; alpha-Chlorohydrin; Animals; Biological Monitoring; Biomarkers; Chromatography, High Pressure Liquid; Epoxy Compounds; Female; Humans; Isomerism; Male; Metabolomics; Propanols; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Young Adult

2019
Verification and evaluation of monochloropropanediol (MCPD) esters and glycidyl esters in palm oil products of different regions in Malaysia.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2019, Volume: 36, Issue:11

    Topics: alpha-Chlorohydrin; Epoxy Compounds; Esters; Fatty Acids; Food Analysis; Food Contamination; Glycerol; Malaysia; Palm Oil; Propanols; Reproducibility of Results

2019
Updated occurrence of 3-monochloropropane-1,2-diol esters (3-MCPD) and glycidyl esters in infant formulas purchased in the United States between 2017 and 2019.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2020, Volume: 37, Issue:3

    Topics: alpha-Chlorohydrin; Epoxy Compounds; Esters; Fatty Acids; Infant Formula; Propanols; United States

2020
Mitigation of 3-MCPD esters and glycidyl esters during the physical refining process of palm oil by micro and macro laboratory scale refining.
    Food chemistry, 2020, Oct-30, Volume: 328

    Topics: alpha-Chlorohydrin; Color; Epoxy Compounds; Esters; Food Quality; Food-Processing Industry; Laboratories; Malaysia; Palm Oil; Phosphoric Acids; Propanols; Temperature

2020
Monochloropropanediol esters and glycidyl esters in dietary supplements based on fish oils.
    Food additives & contaminants. Part B, Surveillance, 2020, Volume: 13, Issue:4

    Topics: alpha-Chlorohydrin; Animals; Cod Liver Oil; Dietary Supplements; Diglycerides; Epoxy Compounds; Esters; Fish Oils; Food Contamination; Glycerol; Humans; Liver; Maximum Allowable Concentration; Propanols; Sharks

2020
3-MCPD and glycidol coexposure induces systemic toxicity and synergistic nephrotoxicity via NLRP3 inflammasome activation, necroptosis, and autophagic cell death.
    Journal of hazardous materials, 2021, 03-05, Volume: 405

    Topics: alpha-Chlorohydrin; Animals; Autophagic Cell Death; Epoxy Compounds; Esters; Food Contamination; Inflammasomes; Male; Mice; Mice, Inbred C57BL; Necroptosis; NLR Family, Pyrin Domain-Containing 3 Protein; Propanols

2021
In-house validation of accelerated solvent extraction-gas chromatography-mass spectrometry for the determination of bound 3- and 2-monochloropropanediols (MCPD) and glycidol in food products.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2021, Volume: 38, Issue:2

    Topics: alpha-Chlorohydrin; Epoxy Compounds; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Glycerol; Propanols; Solvents

2021
Dietary exposure to fatty acid esters of monochloropropanediols and glycidol of 2- to 3-year-old children attending nursery schools from two areas in China using the duplicate-diet collection method.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2021, Volume: 38, Issue:1

    Topics: alpha-Chlorohydrin; Child, Preschool; China; Dietary Exposure; Epoxy Compounds; Esters; Fatty Acids; Female; Food Analysis; Food Contamination; Glycerol; Humans; Male; Propanols; Schools, Nursery

2021
Determination of 3-monochloropropanediol esters and glycidyl esters in fatty matrices by ultra-high performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. A, 2021, Feb-22, Volume: 1639

    Topics: alpha-Chlorohydrin; Chromatography, High Pressure Liquid; Epoxy Compounds; Esters; Fatty Acids; Food Contamination; Limit of Detection; Margarine; Olive Oil; Propanols; Reference Standards; Reproducibility of Results; Soybean Oil; Tandem Mass Spectrometry

2021
Puerarin inhibited 3-chloropropane-1,2-diol fatty acid esters formation by reacting with glycidol and glycidyl esters.
    Food chemistry, 2021, Oct-01, Volume: 358

    Topics: alpha-Chlorohydrin; Chromatography, Liquid; Epoxy Compounds; Esters; Fatty Acids; Hot Temperature; Isoflavones; Palm Oil; Polyphenols; Propanols; Tandem Mass Spectrometry

2021
Apoptosis is induced by sub-acute exposure to 3-MCPD and glycidol on Wistar Albino rat brain cells.
    Environmental toxicology and pharmacology, 2021, Volume: 87

    Topics: alpha-Chlorohydrin; Animals; Apoptosis; Apoptosis Inducing Factor; Brain; Caspase 3; Chemosterilants; Epoxy Compounds; Male; MicroRNAs; Propanols; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats, Wistar

2021
Associations of 3-monochloropropane-1,2-diol and glycidol with prevalence of metabolic syndrome: Findings from Lanxi Nutrition and Safety Study.
    Environmental research, 2022, Volume: 209

    Topics: Acetylcysteine; Adult; Aged; alpha-Chlorohydrin; Epoxy Compounds; Humans; Metabolic Syndrome; Middle Aged; Prevalence; Propanols; Risk Factors; Tandem Mass Spectrometry

2022
Urinary non-targeted toxicokinetics and metabolic fingerprinting of exposure to 3-monochloropropane-1,2-diol and glycidol from refined edible oils.
    Food research international (Ottawa, Ont.), 2022, Volume: 152

    Topics: Acetylcysteine; alpha-Chlorohydrin; Animals; Epoxy Compounds; Plant Oils; Propanols; Rats; Toxicokinetics

2022
Levels of 2,3-dihydroxypropyl mercapturic acid (DHPMA) in human urine do not reflect the exposure to 3-chloro-1,2-propanediol (3-MCPD) or glycidol.
    Environmental research, 2022, Volume: 211

    Topics: Acetylcysteine; alpha-Chlorohydrin; Epoxy Compounds; Esters; Glycerol; Humans; Propanols

2022
Solid-liquid equilibrium of free form of oil contaminants (3-MCPD and glycidol) in lipidic systems.
    Food research international (Ottawa, Ont.), 2022, Volume: 160

    Topics: alpha-Chlorohydrin; Epoxy Compounds; Oils; Propanols

2022
Occurrence of glycidyl esters in infant formula products on the Canadian market between 2015 and 2019.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2023, Volume: 40, Issue:1

    Topics: alpha-Chlorohydrin; Canada; Chromatography, Liquid; Epoxy Compounds; Esters; Food Contamination; Humans; Infant; Infant Formula; Plant Oils; Tandem Mass Spectrometry

2023
Development of physiologically based toxicokinetic models for 3-monochloropropane-1,2-diol and glycidol.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2023, Volume: 172

    Topics: alpha-Chlorohydrin; Animals; Epoxy Compounds; Male; Models, Biological; Propanols; Rats; Toxicokinetics

2023
Food processing contaminants: Dietary exposure to 3-MCPD and glycidol and associated burden of disease for Italian consumers.
    Environmental research, 2023, 10-01, Volume: 234

    Topics: Adolescent; alpha-Chlorohydrin; Cost of Illness; Dietary Exposure; Food Contamination; Food Handling; Humans; Infant; Italy; Neoplasms

2023