Page last updated: 2024-08-18

alpha-chlorohydrin and 1,3-dichloro-2-propanol

alpha-chlorohydrin has been researched along with 1,3-dichloro-2-propanol in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (5.06)	18.7374
1990's	19 (24.05)	18.2507
2000's	22 (27.85)	29.6817
2010's	24 (30.38)	24.3611
2020's	10 (12.66)	2.80

Authors

Authors	Studies
Nagasawa, T; Nakamura, T; Watanabe, I; Yamada, H; Yu, F	1
Imazu, K; Inoue, N; Koga, M; Shinoki, Y; Yamada, N	1
Fujishiro, K; Imazu, K; Inoue, N; Iwasa, T; Koga, M	1
Deininger, C; Eder, E; Hahn, H	1
Marquardt, H; Piasecki, A; Ruge, A	1
Beernaert, H; Van Rillaer, W	1
Atri, FR	1
Bantjes, A; Chamuleau, RA; de Koning, HW	1
Cerná, M; Davídek, J; Silhánková, L; Smíd, F; Velísek, J	1
Hirata, M; Inoue, N; Omura, M; Tanaka, A; Zhao, M	1
Fujishiro, K; Imazu, K; Inoue, N; Makita, Y	1
Furuta, A; Haratake, J; Hashimoto, H	1
Mizobata, Y; Shiozaki, T; Sugimoto, H; Sugimoto, T; Yoshioka, T	1
Furuta, A; Haratake, J; Imazu, K; Iwasa, T; Wakasugi, C	1
Wienecke, J	1
Bull, AT; Fauzi, AM; Hardman, DJ	1
Fry, JR; Hammond, AH	2
Fry, JR; Murthy, A; Robinson, A; Stott, I; Thomas, NW	1
Frei, H; Würgler, FE	1
Fry, JR; Garle, MJ; Sinclair, C; Thurley, P	1
Fry, JR; Piper, CH; Sinclair, D; Thomas, NW; Townsend, SL	1
Arashidani, K; Fueta, Y; Katoh, T; Kikuchi, M; Kohshi, K; Munaka, M; Yamamura, K; Yoshikawa, M	1
Brereton, PA; Crews, C; LeBrun, G	1
Fry, JR; Garle, MJ; Hammond, AH; Sooriakumaran, P	1
Cheng, SC; Chung, WC; Hui, KY	1
Clothier, RH; L'Huillier, N; Pratten, MK	1
Fueta, Y; Imai, H; Katoh, T; Kohshi, K; Kuroda, Y; Nakao, H	1
Bastos, F; Bessa, J; Castro, PM; De Marco, P; Jorge, RF; Pacheco, CC; Silva, M	1
Diachenko, GW; Nyman, PJ; Perfetti, GA	2
Brereton, P; Chapman, S; Crews, C; Hasnip, S; Hough, P; Matthews, W; Potter, N; Todd, J	1
Fan, G; Jiang, D; Zhou, W	1
Kainz, M; Krska, R; Nurmi-Legat, J; Oberhauser, A; Schuhmacher, R	1
Han, J; Ren, Y; Shen, X; Wu, P; Xu, X	1
Christakopoulos, P; Kekos, D; Mamma, D; Papadopoulou, E; Petroutsos, D	1
Malamis, D; Nikolaki, MD; Philippopoulos, CJ; Poulopoulos, SG	1
Chiu, TC; Dou, J; Lee, MR	1
Nikolaki, MD; Philippopoulos, CJ	1
Kim, HY; Kim, JC; Kim, MK; Lee, SB; Lim, KT	1
Ahn, TH; Kim, JC; Kim, KH; Kim, SH; Kim, YB; Lee, JC; Moon, C; Park, SC; Shin, DH; Shin, IS	1
Liu, DL; Yang, JP; Zhang, LX	1
Carro, AM; Cela, R; Fajar, N; González, P; Lorenzo, RA	1
Clothier, RH; Hurst, H; Pratten, M	1
Kim, YH; Lee, SJ; Park, SY	1
Leblanc, JC; Setzer, RW; Williams, G	1
Chai, XS; Tao, ZY; Wu, SB	1
Carro, AM; González, P; Lorenzo, RA; Racamonde, I	2
Abe, K; Kera, Y; Obana, Y; Okada, S; Takahashi, S	1
Badawi, HM	1
Du, EH; Hu, ZC; Zheng, YG; Zou, SP	1
Guan, S; Hu, S; Huang, G; Lu, J; Wang, Z	1
Bai, S; Bai, W; Hu, Y; Huang, Y; Li, G; Li, M; Su, Z; Sun, J; Yan, R; Zhang, L; Zou, F	1
Gao, AC; Liu, ZQ; Shen, YC; Wang, YJ; Zheng, YG	1
Chung, SW; Ho, YY; Kwong, KP; Xiao, Y; Yau, JC	1
Fennell, TR; Gaudette, NF; Hong, Y; Waidyanatha, S	1
Deng, X; Fang, B; Guan, S; Huang, G; Lu, J; Ren, M; Wang, Y; Zhang, S	1
Kim, HC; Kim, JC; Kim, SH; Ko, JW; Lee, IC; Lee, SM; Moon, OS; Shin, IS; Yoon, WK	1
Jeong, GW; Jeong, YY; Kang, HK; Kim, GW; Kim, JC; Kim, JK; Kim, YH; Oh, CH; Park, JG; Yoon, W	1
Deng, W; Feng, J; Liao, Q; Tang, L; Tong, Y; Wu, Z; Xin, D; Yu, H	1
Chai, XS; Chen, RQ; Wan, XF; Yan, N	1
Deng, X; Fang, B; Guan, S; Huang, G; Lu, J; Wang, Z; Yu, X; Zheng, Y	1
Han, J; He, P; Liu, X; Mi, Y; Tang, M; Wang, Z; Xiao, C	1
Cheng, B; Fang, B; Guan, S; Li, T; Liu, M; Lu, J; Meng, Z; Sun, M	1
Gu, K; Zheng, YG; Zou, SP	1
Fang, B; Guan, S; Huang, Y; Jin, Y; Lu, J; Sun, B; Tao, S	1
Cheng, B; Guan, S; Li, T; Liu, M; Lu, J; Meng, Z; Sun, M	1
Adeyiga, AB; Ajala-Lawal, RA; Ajiboye, TO	1
Jenatabadi, HS; Khor, SM; Lee, BQ; Low, KH; Wan Mohamed Radzi, CWJB; Wong, SF	1
Fang, R; Gul, I; Jiang, Q; Tang, L; Wang, Q	1
Fan, Y; Guan, S; Liu, M; Lu, J; Zhang, Q	1
Brauer, B; Korte, R; Schulz, S	1
Ishii, Y; Matsushita, K; Morikawa, T; Ogawa, K; Takasu, S; Toyoda, T; Yamada, T	1
Chen, YF; Gao, J; Li, D; Mo, CH; Sui, HX; Wu, ZC; Yang, DY; Zeng, Y; Zhong, HN	1
Fan, Y; Guan, S; Liu, J; Lu, J; Yu, Z; Zhang, R	1
Jeong, JS; Kim, CY; Kim, JC; Kim, JH; Kim, JW; Kim, TW; Ko, JW; Lim, JO	1
Guan, S; Lu, J; Meng, Z; Zhang, R; Zhao, Y	1
Fan, Y; Guan, S; Lu, J; Qu, X; Yu, Z	1

Reviews

1 review(s) available for alpha-chlorohydrin and 1,3-dichloro-2-propanol

Article	Year
[Toxicity of dichloropropanols]. Journal of UOEH, 2002, Sep-01, Volume: 24, Issue:3 Topics: alpha-Chlorohydrin; Animals; Chlorohydrins; Mice; Rats	2002

Other Studies

78 other study(ies) available for alpha-chlorohydrin and 1,3-dichloro-2-propanol

Article	Year
Resolution and some properties of enzymes involved in enantioselective transformation of 1,3-dichloro-2-propanol to (R)-3-chloro-1,2-propanediol by Corynebacterium sp. strain N-1074. Journal of bacteriology, 1992, Volume: 174, Issue:23 Topics: alpha-Chlorohydrin; Bacterial Proteins; Biotransformation; Corynebacterium; Stereoisomerism; Subcellular Fractions; Substrate Specificity	1992
Identification and quantitative analysis of urinary metabolites of dichloropropanols in rats. Journal of UOEH, 1992, Mar-01, Volume: 14, Issue:1 Topics: alpha-Chlorohydrin; Animals; Chlorohydrins; Gas Chromatography-Mass Spectrometry; Hydroxylation; Male; Propylene Glycols; Rats; Rats, Inbred Strains	1992
[Toxicity of dichloropropanols--changes in hematological findings and serum chemistry]. Journal of UOEH, 1992, Mar-01, Volume: 14, Issue:1 Topics: Alkaline Phosphatase; alpha-Chlorohydrin; Animals; Blood Chemical Analysis; Blood Urea Nitrogen; Chlorohydrins; L-Lactate Dehydrogenase; Leukocyte Count; Liver; Male; Platelet Count; Rats; Rats, Inbred Strains; Transaminases	1992
Genotoxicity of 1,3-dichloro-2-propanol in the SOS chromotest and in the Ames test. Elucidation of the genotoxic mechanism. Chemico-biological interactions, 1991, Volume: 80, Issue:1 Topics: Alcohol Dehydrogenase; alpha-Chlorohydrin; Animals; Biotransformation; Dose-Response Relationship, Drug; Escherichia coli; Gas Chromatography-Mass Spectrometry; Microsomes, Liver; Mutagenicity Tests; Mutagens; Salmonella typhimurium; SOS Response, Genetics	1991
Malignant transformation of mouse M2-fibroblasts by glycerol chlorohydrines contained in protein hydrolysates and commercial food. Arzneimittel-Forschung, 1990, Volume: 40, Issue:9 Topics: alpha-Chlorohydrin; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Food Contamination; Male; Mice; Mice, Inbred C3H; Protein Hydrolysates	1990
Determination of residual 1,3-dichloro-2-propanol in protein hydrolysates by capillary gas chromatography. Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1989, Volume: 188, Issue:4 Topics: alpha-Chlorohydrin; Chlorohydrins; Chromatography, Gas; Food Contamination; Protein Hydrolysates	1989
[Chlorinated hydrocarbons in the environment IV. Chlorbenzol, 1,2,4-trichlorbenzol, chlornitrobenzole, chloraniline, 2-chlorethanol, 1,3-dichlorpropanol (2), epichlorhydrin]. Schriftenreihe des Vereins fur Wasser-, Boden- und Lufthygiene, 1986, Volume: 70 Topics: alpha-Chlorohydrin; Aniline Compounds; Animals; Chlorobenzenes; Environmental Pollutants; Epichlorohydrin; Ethylene Chlorohydrin; Europe; Germany, West; Humans; Hydrocarbons, Chlorinated; Japan; Nitrobenzenes; United States	1986
Crosslinked agarose encapsulated sorbents resistant to steam sterilization. Preparation and mechanical properties. Journal of biomedical materials research, 1984, Volume: 18, Issue:1 Topics: Adsorption; alpha-Chlorohydrin; Capsules; Cross-Linking Reagents; Hemoperfusion; Sepharose; Steam; Sterilization	1984
Mutagenicity of glycerol chlorohydrines and of their esters with higher fatty acids present in protein hydrolysates. Mutation research, 1982, Volume: 103, Issue:1 Topics: alpha-Chlorohydrin; Animals; Biotransformation; Chlorohydrins; Dose-Response Relationship, Drug; Escherichia coli; Esters; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Protein Hydrolysates; Salmonella typhimurium; Structure-Activity Relationship	1982
Comparative testicular toxicities of two isomers of dichloropropanol, 2,3-dichloro-1-propanol, and 1,3-dichloro-2-propanol, and their metabolites alpha-chlorohydrin and epichlorohydrin, and the potent testicular toxicant 1,2-dibromo-3-chloropropane. Bulletin of environmental contamination and toxicology, 1995, Volume: 55, Issue:1 Topics: alpha-Chlorohydrin; Animals; Body Weight; Chlorohydrins; Epichlorohydrin; Epididymis; Injections, Subcutaneous; Insecticides; Male; Mutagens; Occupational Exposure; Organ Size; Propane; Rats; Rats, Wistar; Reproduction; Seminiferous Tubules; Sperm Count; Spermatids; Spermatozoa; Testis	1995
Liver injury induced by dichloropropanols--changes in the time course on hematological and blood chemical examinations. Fukuoka igaku zasshi = Hukuoka acta medica, 1994, Volume: 85, Issue:8 Topics: Alanine Transaminase; alpha-Chlorohydrin; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chlorohydrins; Environmental Monitoring; Liver; Liver Diseases; Male; Platelet Count; Rats; Rats, Wistar	1994
Immunohistochemical and ultrastructural study of hepatic sinusoidal linings during dichloropropanol-induced acute hepatic necrosis. Liver, 1994, Volume: 14, Issue:2 Topics: Acute Disease; alpha-Chlorohydrin; Animals; Chemical and Drug Induced Liver Injury; Collagen; Immunohistochemistry; Liver; Liver Diseases; Liver Regeneration; Macrophages; Male; Necrosis; Rats; Rats, Wistar	1994
Fulminant hepatitis following exposure to dichlorohydrin--report of two cases. Human & experimental toxicology, 1994, Volume: 13, Issue:4 Topics: Adult; alpha-Chlorohydrin; Chemical and Drug Induced Liver Injury; Epichlorohydrin; Fatal Outcome; Gas Chromatography-Mass Spectrometry; Humans; Male; Occupational Exposure	1994
Submassive hepatic necrosis induced by dichloropropanol. Liver, 1993, Volume: 13, Issue:3 Topics: Adult; alpha-Chlorohydrin; Animals; Chemical and Drug Induced Liver Injury; Cross-Linking Reagents; Hepatic Encephalopathy; Humans; Liver; Male; Middle Aged; Mutagens; Necrosis; Occupational Diseases; Rats; Rats, Wistar	1993
1,3-Dichloropropanol-(2) as an indicator of exposure to epichlorohydrine. Clinical chemistry, 1993, Volume: 39, Issue:2 Topics: alpha-Chlorohydrin; Environmental Exposure; Epichlorohydrin; Gas Chromatography-Mass Spectrometry; Humans	1993
Biodehalogenation of low concentrations of 1,3-dichloropropanol by mono- and mixed cultures of bacteria. Applied microbiology and biotechnology, 1996, Volume: 46, Issue:5-6 Topics: alpha-Chlorohydrin; Biodegradation, Environmental; Biofilms; Colony Count, Microbial; Culture Media; Electrophoresis, Polyacrylamide Gel; Hydrocarbons, Halogenated; Hydrolases; Kinetics; Pseudomonas; Rhizobium; Soil Microbiology	1996
Involvement of cytochrome P4502E1 in the toxicity of dichloropropanol to rat hepatocyte cultures. Toxicology, 1997, Mar-28, Volume: 118, Issue:2-3 Topics: 1-Propanol; Acetone; alpha-Chlorohydrin; Analysis of Variance; Animals; Antidotes; Benzopyrans; Cell Death; Cells, Cultured; Chlorohydrins; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Ditiocarb; Drug Interactions; Enzyme Activation; Enzyme Induction; Glutathione; Insecticides; Isoniazid; L-Lactate Dehydrogenase; Liver; Male; Mutagens; Plants; Propanols; Rats; Rats, Wistar	1997
Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1,3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat. Human & experimental toxicology, 1997, Volume: 16, Issue:5 Topics: alpha-Chlorohydrin; Animals; Cross-Linking Reagents; Cytochrome P-450 CYP2E1 Inhibitors; Ditiocarb; Liver; Male; Rats; Rats, Wistar	1997
The vicinal chloroalcohols 1,3-dichloro-2-propanol (DC2P), 3-chloro-1,2-propanediol (3CPD) and 2-chloro-1,3-propanediol (2CPD) are not genotoxic in vivo in the wing spot test of Drosophila melanogaster. Mutation research, 1997, Nov-27, Volume: 394, Issue:1-3 Topics: alpha-Chlorohydrin; Animals; Biotransformation; Drosophila melanogaster; Mutagens; Wings, Animal	1997
Haloalcohols deplete glutathione when incubated with fortified liver fractions. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:5 Topics: Acetylcysteine; alpha-Chlorohydrin; Animals; Chlorohydrins; Cytochrome P-450 Enzyme System; Free Radical Scavengers; Glutathione; Glutathione Transferase; Isoenzymes; Liver; Male; Microsomes, Liver; Propanols; Rats; Rats, Wistar	1999
Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1,3-dichloro-2-propanol hepatotoxicity in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:4 Topics: alpha-Chlorohydrin; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Enzyme Activation; Fasting; Glutathione; Liver Diseases; Male; Organ Size; Proteins; Rats; Rats, Wistar; Toxicity Tests	1999
Effect of cyanamide on toxicity and glutathione depletion in rat hepatocyte cultures: differences between two dichloropropanol isomers. Chemico-biological interactions, 1999, Sep-30, Volume: 122, Issue:2 Topics: Aldehyde Dehydrogenase; alpha-Chlorohydrin; Animals; Cells, Cultured; Chlorohydrins; Cyanamide; Drug Synergism; Enzyme Inhibitors; Glutathione; Isomerism; Liver; Male; Propanols; Rats; Rats, Wistar	1999
[Disseminated intravascular coagulation after acute hepatic injury in rats induced by 1,3-dichloro-2-propanol]. Sangyo eiseigaku zasshi = Journal of occupational health, 1999, Volume: 41, Issue:6 Topics: Acute Disease; alpha-Chlorohydrin; Animals; Chemical and Drug Induced Liver Injury; Disseminated Intravascular Coagulation; Male; Rats; Rats, Wistar	1999
Determination of 1,3-dichloropropanol in soy sauces by automated headspace gas chromatography-mass spectrometry. Food additives and contaminants, 2002, Volume: 19, Issue:4 Topics: alpha-Chlorohydrin; Food Analysis; Food Contamination; Food Handling; Gas Chromatography-Mass Spectrometry; Glycine max; Humans; Reproducibility of Results; Sensitivity and Specificity	2002
Modulation of hepatocyte thiol content by medium composition: implications for toxicity studies. Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:3 Topics: Acetone; alpha-Chlorohydrin; Amino Acids, Sulfur; Animals; Cell Culture Techniques; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Hepatocytes; Male; Maleates; Propanols; Rats; Rats, Wistar; Toxicity Tests	2002
Sensitive method for the determination of 1,3-dichloropropan-2-ol and 3-chloropropane-1,2-diol in soy sauce by capillary gas chromatography with mass spectrometric detection. Journal of chromatography. A, 2002, Apr-05, Volume: 952, Issue:1-2 Topics: alpha-Chlorohydrin; Food Analysis; Gas Chromatography-Mass Spectrometry; Glycine max; Reproducibility of Results; Sensitivity and Specificity	2002
The relative embryotoxicity of 1,3-dichloro-2-propanol on primary chick embryonic cells. Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:4 Topics: alpha-Chlorohydrin; Animals; Chick Embryo; Dose-Response Relationship, Drug; Limb Buds; Mesencephalon; Mutagens	2002
Enrichment of microbial cultures able to degrade 1,3-dichloro-2-propanol: a comparison between batch and continuous methods. Biodegradation, 2002, Volume: 13, Issue:3 Topics: alpha-Chlorohydrin; Bacteria; Chlorides; Culture Media; Environmental Pollution; Mutagens; Rhizobiaceae; RNA, Ribosomal, 16S; Soil Microbiology	2002
Determination of 1,3-dichloropropanol in soy and related sauces by using gas chromatography/mass spectrometry. Food additives and contaminants, 2003, Volume: 20, Issue:10 Topics: alpha-Chlorohydrin; Condiments; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Glycine max; Humans; Reproducibility of Results	2003
Survey of chloropropanols in soy sauces and related products. Food additives and contaminants, 2003, Volume: 20, Issue:10 Topics: alpha-Chlorohydrin; Carcinogens; Condiments; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Glycine max; Humans; Quality Control	2003
Survey of chloropropanols in soy sauces and related products purchased in the UK in 2000 and 2002. Food additives and contaminants, 2003, Volume: 20, Issue:10 Topics: alpha-Chlorohydrin; Carcinogens; Condiments; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Glycine max; Humans; Quality Assurance, Health Care; United Kingdom	2003
[Determination of residual epichlorohydrin and sym-dichloroisopropyl alcohol in cationic etherified reagent by gas chromatography]. Se pu = Chinese journal of chromatography, 2004, Volume: 22, Issue:6 Topics: alpha-Chlorohydrin; Cations; Chromatography, Gas; Epichlorohydrin	2004
A rapid and sensitive GC-MS method for determination of 1,3-dichloro-2-propanol in water. Analytical and bioanalytical chemistry, 2005, Volume: 382, Issue:2 Topics: alpha-Chlorohydrin; Ammonium Sulfate; Calibration; Gas Chromatography-Mass Spectrometry; Humic Substances; Reference Standards; Sensitivity and Specificity; Water Pollutants, Chemical	2005
The simultaneous separation and determination of chloropropanols in soy sauce and other flavoring with gas chromatography-mass spectrometry in negative chemical and electron impact ionization modes. Food additives and contaminants, 2006, Volume: 23, Issue:2 Topics: alpha-Chlorohydrin; Carcinogens; Chemosterilants; Chlorohydrins; Cross-Linking Reagents; Ethylamines; Flavoring Agents; Fluorocarbons; Food Contamination; Gas Chromatography-Mass Spectrometry; Soy Foods	2006
Removal of 1,3-dichloro2-propanol and 3-chloro1,2-propanediol by the whole cell system of pseudomonas putida DSM 437. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2006, Volume: 41, Issue:3 Topics: alpha-Chlorohydrin; Biodegradation, Environmental; Biomass; Industrial Waste; Kinetics; Pseudomonas putida; Waste Disposal, Fluid; Water Purification	2006
Photocatalytical degradation of 1,3-dichloro-2-propanol aqueous solutions by using an immobilized TiO2 photoreactor. Journal of hazardous materials, 2006, Sep-21, Volume: 137, Issue:2 Topics: alpha-Chlorohydrin; Catalysis; Hydrogen Peroxide; Solutions; Titanium; Ultraviolet Rays; Water	2006
Determination of 1,3-dichloro-2-propanol and 3-chloro-1,2-propandiol in soy sauce by headspace derivatization solid-phase microextraction combined with gas chromatography-mass spectrometry. Analytica chimica acta, 2007, May-22, Volume: 591, Issue:2 Topics: alpha-Chlorohydrin; Gas Chromatography-Mass Spectrometry; Mutagens; Reproducibility of Results; Solid Phase Microextraction; Soy Foods	2007
Photochemical degradation of 1,3-dichloro-2-propanol aqueous solutions. Journal of hazardous materials, 2007, Jul-31, Volume: 146, Issue:3 Topics: alpha-Chlorohydrin; Hydrogen Peroxide; Oxidants; Photolysis; Solutions; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification	2007
subchronic inhalation toxicity study of 1,3-dichloro-2-propanol in rats. The Annals of occupational hygiene, 2007, Volume: 51, Issue:7 Topics: alpha-Chlorohydrin; Animals; Chemical and Drug Induced Liver Injury; Eating; Female; Inhalation Exposure; Kidney Diseases; Male; Organ Size; Proteinuria; Rats; Rats, Inbred F344; Toxicity Tests, Chronic; Weight Gain	2007
Developmental toxic potential of 1,3-dichloro-2-propanol in Sprague-Dawley rats. Regulatory toxicology and pharmacology : RTP, 2009, Volume: 53, Issue:1 Topics: Administration, Oral; alpha-Chlorohydrin; Animals; Dose-Response Relationship, Drug; Eating; Female; Fetal Development; Fetal Weight; Male; Maternal Exposure; Mutagens; No-Observed-Adverse-Effect Level; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Weight Gain	2009
[Gas chromatography for determination of 1, 3-dichloro-2-propanol in air of working places]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2008, Volume: 26, Issue:8 Topics: Air Pollutants, Occupational; alpha-Chlorohydrin; Chromatography, Gas; Workplace	2008
Solid-phase micro-extraction procedure for the determination of 1,3-dichloro-2-propanol in water by on-fibre derivatisation with bis(trimethylsilyl)trifluoroacetamide. Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:3 Topics: Acetamides; alpha-Chlorohydrin; Hydrogen-Ion Concentration; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Microextraction; Temperature; Time Factors; Trimethylsilyl Compounds; Water	2009
An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial. Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:4 Topics: Acetone; alpha-Chlorohydrin; Animal Testing Alternatives; Animals; Cell Count; Cell Culture Techniques; Cell Differentiation; Cell Separation; Cell Survival; Cells, Cultured; Chick Embryo; Culture Media; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Embryonic Stem Cells; Ethionine; Fluorouracil; Indicators and Reagents; Methionine; Myocardial Contraction; Myocytes, Cardiac; Neutral Red; Organic Chemicals; Oxazines; Sulfanilamide; Sulfanilamides; Sulfisoxazole; Teratogens; Time Factors; Toxicity Tests; Uracil; Xanthenes	2009
1,3-Dichloro-2-propanol induces apoptosis via both calcium and ROS in mouse melanoma cells. Biotechnology letters, 2010, Volume: 32, Issue:1 Topics: alpha-Chlorohydrin; Animals; Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Melanoma; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Transport; Reactive Oxygen Species	2010
Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic: example: (CAS No. 96-23-1) 1,3-dichloro-2-propanol (DCP). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48 Suppl 1 Topics: alpha-Chlorohydrin; Animals; Carcinogens; Data Interpretation, Statistical; Diet; Dose-Response Relationship, Drug; Female; Food Contamination; Humans; Male; Models, Statistical; Mutagens; Neoplasms; Rats	2010
Determination of epichlorohydrin and 1,3-dichloro-2-propanol in synthesis of cationic etherifying reagent by headspace gas chromatography. Journal of chromatography. A, 2011, Sep-16, Volume: 1218, Issue:37 Topics: alpha-Chlorohydrin; Chromatography, Gas; Epichlorohydrin; Propanols; Quaternary Ammonium Compounds; Reproducibility of Results; Sensitivity and Specificity; Silver Nitrate; Sulfates	2011
Combined solid-phase extraction and gas chromatography-mass spectrometry used for determination of chloropropanols in water. Journal of separation science, 2011, Volume: 34, Issue:19 Topics: alpha-Chlorohydrin; Gas Chromatography-Mass Spectrometry; Glycerol; Sewage; Solid Phase Extraction; Water Pollutants, Chemical	2011
Determination of chloropropanols in foods by one-step extraction and derivatization using pressurized liquid extraction and gas chromatography-mass spectrometry. Journal of chromatography. A, 2011, Sep-28, Volume: 1218, Issue:39 Topics: alpha-Chlorohydrin; Analysis of Variance; Bread; Chemical Fractionation; Edible Grain; Gas Chromatography-Mass Spectrometry; Glycerol; Reproducibility of Results; Sensitivity and Specificity; Temperature; Trimethylsilyl Compounds	2011
Complete detoxification of tris(1,3-dichloro-2-propyl) phosphate by mixed two bacteria, Sphingobium sp. strain TCM1 and Arthrobacter sp. strain PY1. Journal of bioscience and bioengineering, 2012, Volume: 113, Issue:1 Topics: alpha-Chlorohydrin; Arthrobacter; Biodegradation, Environmental; Cold Temperature; Flame Retardants; Freeze Drying; Halogenation; Hydrogen-Ion Concentration; Organophosphates; Phosphorylation; Soil Microbiology; Sphingomonadaceae	2012
A study of the molecular structure and vibrational spectra of 1,3-dichloro-2-propanol and 1,1,1-trichloro-2-methyl-2-propanol (chlorobutanol). Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Feb-15, Volume: 87 Topics: alpha-Chlorohydrin; Chlorobutanol; Models, Molecular; Molecular Conformation; Mutagens; Preservatives, Pharmaceutical; Spectrum Analysis, Raman	2012
Enhanced biotransformation of 1,3-dichloro-2-propanol to epichlorohydrin via resin-based in situ product removal process. Biotechnology letters, 2013, Volume: 35, Issue:6 Topics: Adsorption; alpha-Chlorohydrin; Biotechnology; Biotransformation; Enzyme Inhibitors; Epichlorohydrin; Escherichia coli; Hydrolases; Polymers; Recombinant Proteins	2013
1,3-Dichloro-2-propanol induced hyperlipidemia in C57BL/6J mice via AMPK signaling pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 64 Topics: Adenylate Kinase; alpha-Chlorohydrin; Animals; Hyperlipidemias; Mice; Mice, Inbred C57BL; Signal Transduction	2014
1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells. Food chemistry, 2014, Jul-01, Volume: 154 Topics: 17-Hydroxysteroid Dehydrogenases; alpha-Chlorohydrin; Animals; Apoptosis; Cell Line; Cell Survival; Cyclic AMP; Cytochrome P-450 Enzyme System; Down-Regulation; Leydig Cells; Male; Phosphoproteins; Progesterone; Rats	2014
Expression, characterization, and improvement of a newly cloned halohydrin dehalogenase from Agrobacterium tumefaciens and its application in production of epichlorohydrin. Journal of industrial microbiology & biotechnology, 2014, Volume: 41, Issue:7 Topics: Agrobacterium tumefaciens; alpha-Chlorohydrin; Biocatalysis; Biotransformation; Catalytic Domain; Cloning, Molecular; Enzyme Stability; Epichlorohydrin; Escherichia coli; Gas Chromatography-Mass Spectrometry; Half-Life; Hydrogen-Ion Concentration; Hydrolases; Metals; Models, Molecular; Molecular Docking Simulation; Mutagenesis, Site-Directed; Substrate Specificity; Temperature	2014
Dietary exposure to chloropropanols of secondary school students in Hong Kong. Food additives & contaminants. Part B, Surveillance, 2008, Volume: 1, Issue:2 Topics: Adolescent; alpha-Chlorohydrin; Diet; Environmental Exposure; Food Contamination; Gas Chromatography-Mass Spectrometry; Hong Kong; Humans; Maximum Allowable Concentration; Schools; Students	2008
Formation of epichlorohydrin, a known rodent carcinogen, following oral administration of 1,3-dichloro-2-propanol in rats. Chemical research in toxicology, 2014, Oct-20, Volume: 27, Issue:10 Topics: Administration, Intravenous; Administration, Oral; alpha-Chlorohydrin; Animals; Area Under Curve; Epichlorohydrin; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Liver; Male; Mice; Rats; Rats, Sprague-Dawley; ROC Curve; Serum	2014
Nonalcoholic fatty liver disease induced by 13-week oral administration of 1,3-dichloro-2-propanol in C57BL/6J mice. Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:3 Topics: Adenylate Kinase; Administration, Oral; alpha-Chlorohydrin; Animals; Lipid Metabolism; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Signal Transduction; Toxicity Tests, Subchronic	2015
Time-course and molecular mechanism of hepatotoxicity induced by 1,3-dichloro-2-propanol in rats. Environmental toxicology and pharmacology, 2015, Volume: 40, Issue:1 Topics: alpha-Chlorohydrin; Animals; Apoptosis; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley	2015
Noninvasive biomarkers for acute hepatotoxicity induced by 1,3-dichloro-2-propanol: hyperpolarized 13C dynamic MR spectroscopy. Magnetic resonance imaging, 2016, Volume: 34, Issue:2 Topics: Alanine; Algorithms; alpha-Chlorohydrin; Animals; Biomarkers; Carbon-13 Magnetic Resonance Spectroscopy; Chemical and Drug Induced Liver Injury; Lactic Acid; Magnetic Resonance Imaging; Male; Molecular Imaging; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity	2016
Exploring the thermostable properties of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by a combinatorial directed evolution strategy. Applied microbiology and biotechnology, 2017, Volume: 101, Issue:8 Topics: Agrobacterium tumefaciens; alpha-Chlorohydrin; Biocatalysis; Directed Molecular Evolution; Enzyme Stability; Gene Library; Hydrolases; Kinetics; Models, Molecular; Mutagenesis; Mutation; Polymerase Chain Reaction; Temperature	2017
Determination of chlorinated volatile organic compounds in polyamine epichlorohydrin solution by headspace gas chromatography. Journal of chromatography. A, 2017, May-05, Volume: 1496 Topics: alpha-Chlorohydrin; Chromatography, Gas; Epichlorohydrin; Limit of Detection; Polyamines; Solutions; Volatile Organic Compounds	2017
1,3-dichloro-2-propanol induced lipid accumulation in HepG2 cells through cAMP/protein kinase A and AMP-activated protein kinase pathways via Gi/o-coupled receptors. Environmental toxicology and pharmacology, 2017, Volume: 55 Topics: alpha-Chlorohydrin; AMP-Activated Protein Kinases; Calcium; Cholesterol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Hep G2 Cells; Humans; Lipid Metabolism; Mutagens; Phosphorylation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Signal Transduction; Triglycerides	2017
1,3-Dichloro-2-propanol evokes inflammation and apoptosis in BV-2 microglia via MAPKs and NF-κB signaling pathways mediated by reactive oxygen species. Toxicology letters, 2018, Mar-01, Volume: 284 Topics: Acetylcysteine; alpha-Chlorohydrin; Animals; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Food Contamination; Membrane Potential, Mitochondrial; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Reactive Oxygen Species; Signal Transduction	2018
Alliin attenuates 1, 3-dichloro-2-propanol-induced lipogenesis in HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway. Life sciences, 2018, Feb-15, Volume: 195 Topics: alpha-Chlorohydrin; AMP-Activated Protein Kinases; Cell Survival; Cholesterol; Cysteine; Enzyme Activation; Gene Expression Regulation; Hep G2 Cells; Humans; Hypolipidemic Agents; Lipid Metabolism; Signal Transduction; Sterol Regulatory Element Binding Proteins; Triglycerides	2018
Covalent immobilization of halohydrin dehalogenase for efficient synthesis of epichlorohydrin in an integrated bioreactor. Biotechnology progress, 2018, Volume: 34, Issue:3 Topics: Agrobacterium tumefaciens; alpha-Chlorohydrin; Bioreactors; Enzymes, Immobilized; Epichlorohydrin; Hydrolases	2018
Epigallocatechin-3-gallate protects against 1,3-dichloro-2-propanol-induced lipid accumulation in C57BL/6J mice. Life sciences, 2018, Sep-15, Volume: 209 Topics: alpha-Chlorohydrin; Animals; Antioxidants; Catechin; Dyslipidemias; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mutagens; Protective Agents	2018
1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 122 Topics: Adenylate Kinase; alpha-Chlorohydrin; Autophagosomes; Autophagy; Biphenyl Compounds; Cell Survival; Enzyme Activators; Food Contamination; Food Safety; Hep G2 Cells; Humans; Imidazoles; Lysosomes; Phosphorylation; Piperazines; Pyrones; Thiophenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53	2018
Caffeic acid abrogates 1,3-dichloro-2-propanol-induced hepatotoxicity by upregulating nuclear erythroid-related factor 2 and downregulating nuclear factor-kappa B. Human & experimental toxicology, 2019, Volume: 38, Issue:9 Topics: alpha-Chlorohydrin; Animals; Caffeic Acids; Chemical and Drug Induced Liver Injury; Down-Regulation; Liver; NF-E2-Related Factor 2; NF-kappa B; Protective Agents; Rats	2019
Estimation of the dietary intake and risk assessment of food carcinogens (3-MCPD and 1,3-DCP) in soy sauces by Monte Carlo simulation. Food chemistry, 2020, May-01, Volume: 311 Topics: Adolescent; Adult; alpha-Chlorohydrin; Carcinogens; Female; Gas Chromatography-Mass Spectrometry; Humans; Malaysia; Male; Middle Aged; Monte Carlo Method; Risk Assessment; Soy Foods	2020
Enzyme immobilization on glass fiber membrane for detection of halogenated compounds. Analytical biochemistry, 2020, 11-15, Volume: 609 Topics: Agrobacterium tumefaciens; alpha-Chlorohydrin; Colorimetry; Enzyme Stability; Enzymes, Immobilized; Fresh Water; Glass; Hydrogen-Ion Concentration; Hydrolases; Limit of Detection; Propanols; Recombinant Proteins; Temperature; Water Pollutants, Chemical	2020
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells. Toxicology, 2021, 04-30, Volume: 454 Topics: alpha-Chlorohydrin; Autophagosomes; Autophagy; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases	2021
Chloropropanols (3-MCPD, 1,3-DCP) from food contact materials: GC-MS method improvement, market survey and investigations on the effect of hot water extraction. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2021, Volume: 38, Issue:6 Topics: alpha-Chlorohydrin; Food Contamination; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Limit of Detection; Liquid-Liquid Extraction; Surveys and Questionnaires; Water	2021
In vivo mutagenicity and tumor-promoting activity of 1,3-dichloro-2-propanol in the liver and kidneys of gpt delta rats. Archives of toxicology, 2021, Volume: 95, Issue:9 Topics: alpha-Chlorohydrin; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Escherichia coli Proteins; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Male; Mutagenesis; Mutagenicity Tests; Mutagens; Pentosyltransferases; Rats; Rats, Inbred F344; Rats, Transgenic	2021
Investigation of factors influencing the release of chloropropanols (3-MCPD and 1,3-DCP) from food contact paper. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2021, Volume: 38, Issue:12 Topics: alpha-Chlorohydrin; Chromatography, Gas; Food Analysis; Food Contamination; Paper; Tandem Mass Spectrometry; Temperature	2021
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 157 Topics: alpha-Chlorohydrin; Animals; Autophagosomes; Autophagy; Blotting, Western; Forkhead Box Protein O1; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Lysosomes; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases	2021
Diallyl disulfide prevents 1,3-dichloro-2-propanol-induced hepatotoxicity through mitogen-activated protein kinases signaling. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 160 Topics: Allyl Compounds; alpha-Chlorohydrin; Animals; Apoptosis; Caspase 3; Cytochrome P-450 CYP2E1; Disulfides; Hep G2 Cells; Humans; Liver Diseases; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Protective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction	2022
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes. Environmental toxicology, 2022, Volume: 37, Issue:10 Topics: alpha-Chlorohydrin; Animals; Carboxylic Ester Hydrolases; Ferroptosis; Glutathione; Hepatocytes; Iron; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Signal Transduction	2022
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway. Journal of agricultural and food chemistry, 2022, Sep-07, Volume: 70, Issue:35 Topics: alpha-Chlorohydrin; Animals; Kidney; Mice; Mice, Inbred C57BL; Necroptosis; NF-E2-Related Factor 2; Protein Kinases; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases	2022