alpha-asarone and 2-amino-3-4-dimethylimidazo(4-5-f)quinoline

alpha-asarone has been researched along with 2-amino-3-4-dimethylimidazo(4-5-f)quinoline* in 1 studies

Other Studies

1 other study(ies) available for alpha-asarone and 2-amino-3-4-dimethylimidazo(4-5-f)quinoline

Article	Year
Suppression of MeIQ-induced SOS response by allylbenzenes from Asiasarum heterotropoides in the Salmonella typhimurium OY1001/1A2 umu test. Natural product research, 2006, Volume: 20, Issue:7 Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was suppressed 70.0, 75.9 and 81.7% at a concentration of 0.4 mM, respectively. The ID50 values (50% inhibition dose) of these compounds were 0.125, 0.098 and 0.059 mM, respectively. On the other hand, compounds 1-3 showed weak suppressive effects of the SOS-inducing activity on activated MeIQ. Topics: Allylbenzene Derivatives; Anisoles; Antimutagenic Agents; Antineoplastic Agents; Aristolochiaceae; Eugenol; Mutagenicity Tests; Mutagens; Pyrogallol; Quinolines; SOS Response, Genetics	2006

Article

Year

Suppression of MeIQ-induced SOS response by allylbenzenes from Asiasarum heterotropoides in the Salmonella typhimurium OY1001/1A2 umu test.

Natural product research, 2006, Volume: 20, Issue:7

Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was suppressed 70.0, 75.9 and 81.7% at a concentration of 0.4 mM, respectively. The ID50 values (50% inhibition dose) of these compounds were 0.125, 0.098 and 0.059 mM, respectively. On the other hand, compounds 1-3 showed weak suppressive effects of the SOS-inducing activity on activated MeIQ.

Topics: Allylbenzene Derivatives; Anisoles; Antimutagenic Agents; Antineoplastic Agents; Aristolochiaceae; Eugenol; Mutagenicity Tests; Mutagens; Pyrogallol; Quinolines; SOS Response, Genetics

2006