Page last updated: 2024-08-25

alpha-amyrin and oleanolic acid

alpha-amyrin has been researched along with oleanolic acid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's9 (52.94)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Hata, K; Hori, K; Takahashi, S1
Ando, M; Fu, L; Hasegawa, T; Hirose, K; Kataoka, T; Kiuchi, M; Li, N; Mitsui, T; Oka, S; Sakai, J; Wang, J; Zhang, S; Zhao, M1
Habib-Jiwan, JL; Hoet, S; Muccioli, GG; Opperdoes, FR; Pieters, L; Quetin-Leclercq, J1
Auwerx, J; Boudjelal, G; Genet, C; Lobstein, A; Saladin, R; Schmidt, C; Schoonjans, K; Souchet, M; Strehle, A; Wagner, A1
Chin, YW; Jee, JG; Jeong, YJ; Keum, YS; Kim, Y; Lee, J; Lee, JM; Yu, MS1
Chin, YW; Choi, BY; Kang, JS; Keum, YS; Kim, YW; Lee, K1
Ahn, HC; Cho, SC; Choi, BY; Fei, X; Keum, YS; Kim, HJ; Lee, K; Seo, SY1
Bastida, J; da Silva, GN; da Silva, MV; Gnoatto, SC; Lopes, NP; Macedo, AJ; Silva, DB; Silva, NL; Tasca, T; Vieira, Pde B1
Chau, VM; Do Thi, T; Doan Thi Mai, H; Litaudon, M; Nguyen, TT; Nguyen, VH; Pham, VC; Truong, BN1
Ding, J; Hu, JF; Li, J; Ma, GL; Wan, J; Wang, PP; Xiong, J1
Fukushima, EO; Muranaka, T; Nomura, Y; Vo, NNQ1
Cui, H; Jin, C; Jin, M; Li, G; Wang, J; Wang, R; Ye, C; Zhou, W; Zhou, Y1
Chen, F; Li, W; Liu, DL; Lv, XM; Shao, LD; Wang, W; Wang, WJ1
Chen, W; Gu, J; Kuang, Z; Wang, K; Wang, M; Wu, Z; Xu, H; Zhan, R; Zhang, F; Zhang, R1
Gao, W; Guo, J; Huang, LQ; Lin, HX; Su, P; Wang, J; Wu, XY; Yang, J; Zhao, H1
Felippe, LG; Furlan, M; Guido, RVC; Mazzeu, BF; Oliveira, AA; Remlinger, M; Souza-Moreira, TM; Valentini, SR; Zanelli, CF1
Alvarez, L; Boto, A; Columba-Palomares, MC; Garduño-Ramírez, ML; González-Christen, J; Maldonado-Magaña, A; Marquina, S; Razo-Hernández, RS; Romero-Estrada, A; Romero-Estudillo, I; Sánchez-Carranza, JN1

Reviews

1 review(s) available for alpha-amyrin and oleanolic acid

ArticleYear
Synthesis, Biological Evaluation, and Molecular Docking Study of 3-Amino and 3-Hydroxy-
    Journal of natural products, 2022, 04-22, Volume: 85, Issue:4

    Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Esters; Hydroxyproline; Lipopolysaccharides; Molecular Docking Simulation; NF-kappa B; Oleanolic Acid; Pentacyclic Triterpenes

2022

Other Studies

16 other study(ies) available for alpha-amyrin and oleanolic acid

ArticleYear
Differentiation- and apoptosis-inducing activities by pentacyclic triterpenes on a mouse melanoma cell line.
    Journal of natural products, 2002, Volume: 65, Issue:5

    Topics: Animals; Apoptosis; Betulinic Acid; Cell Differentiation; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Molecular Structure; Oxidation-Reduction; Pentacyclic Triterpenes; Pyridinium Compounds; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2002
Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.
    Journal of natural products, 2005, Volume: 68, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Screening Assays, Antitumor; Humans; Intercellular Adhesion Molecule-1; Japan; Models, Biological; Molecular Structure; Nerium; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Triterpenes; Tumor Cells, Cultured

2005
Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.
    Journal of natural products, 2007, Volume: 70, Issue:8

    Topics: Animals; Benin; Cell Line, Tumor; Molecular Structure; Plant Leaves; Plants, Medicinal; Sterols; Stigmasterol; Structure-Activity Relationship; Strychnos; Triterpenes; Trypanocidal Agents; Trypanosoma brucei brucei

2007
Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: 3T3-L1 Cells; Animals; Betulinic Acid; CHO Cells; Cricetinae; Cricetulus; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Pentacyclic Triterpenes; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2010
Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.
    Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12

    Topics: Adenosine Triphosphate; Antiviral Agents; Apigenin; Breast; Cell Line; Cell Proliferation; Colorimetry; DNA; DNA Helicases; Epithelial Cells; Female; Flavonoids; Fluorescence Resonance Energy Transfer; Hepacivirus; Humans; Hydrolysis; Inhibitory Concentration 50; Kinetics; Methyltransferases; RNA Helicases; Severe acute respiratory syndrome-related coronavirus; Species Specificity; Viral Nonstructural Proteins; Viral Proteins

2012
Identification of 4'-O-β-D-glucosyl-5-O-methylvisamminol as a novel epigenetic suppressor of histone H3 phosphorylation at Ser10 and its interaction with 14-3-3ε.
    Bioorganic & medicinal chemistry letters, 2014, Oct-01, Volume: 24, Issue:19

    Topics: 14-3-3 Proteins; Cell Survival; Chromones; Epigenesis, Genetic; Glucosides; Histones; HT29 Cells; Humans; Molecular Conformation; Phosphorylation; Serine; Structure-Activity Relationship

2014
Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Binding, Competitive; Drug Discovery; Humans; Isocitrate Dehydrogenase; MCF-7 Cells; Molecular Structure; Mutation; Recombinant Proteins; Structure-Activity Relationship; Xanthones

2015
Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis.
    Bioorganic & medicinal chemistry letters, 2016, May-01, Volume: 26, Issue:9

    Topics: Drug Evaluation, Preclinical; Plant Extracts; Plants, Medicinal; Trichomonas vaginalis

2016
Cytotoxic dammarane-type triterpenoids from the leaves of Viburnum sambucinum.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dammaranes; Drug Screening Assays, Antitumor; Humans; Neoplasms; Plant Leaves; Triterpenes; Viburnum

2017
Camellianols A-G, Barrigenol-like Triterpenoids with PTP1B Inhibitory Effects from the Endangered Ornamental Plant Camellia crapnelliana.
    Journal of natural products, 2017, 11-22, Volume: 80, Issue:11

    Topics: Camellia; Cyclohexanones; Drugs, Chinese Herbal; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Components, Aerial; Plant Leaves; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Triterpenes

2017
Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.
    Journal of natural products, 2019, 12-27, Volume: 82, Issue:12

    Topics: Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Humans; Lipoxygenase Inhibitors; Pentacyclic Triterpenes; Structure-Activity Relationship

2019
A new pentacyclic triterpenoid from the leaves of
    Natural product research, 2020, Volume: 34, Issue:23

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Drug Evaluation, Preclinical; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; RAW 264.7 Cells; Rhododendron; Triterpenes; Ursolic Acid

2020
Bioactive triterpenoids from
    Natural product research, 2020, Volume: 34, Issue:19

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Oleanolic Acid; Pentacyclic Triterpenes; Plant Components, Aerial; RAW 264.7 Cells; Sambucus; Triterpenes; Ursolic Acid

2020
Molecular Docking and Molecular Dynamics Studies on Selective Synthesis of α-Amyrin and β-Amyrin by Oxidosqualene Cyclases from
    International journal of molecular sciences, 2019, Jul-15, Volume: 20, Issue:14

    Topics: Binding Sites; Ilex; Intramolecular Transferases; Molecular Docking Simulation; Oleanolic Acid; Pentacyclic Triterpenes; Plant Proteins; Protein Binding

2019
Molecular cloning and functional characterization of multiple ApOSCs from Andrographis paniculata.
    Chinese journal of natural medicines, 2020, Volume: 18, Issue:9

    Topics: Andrographis; Biosynthetic Pathways; Cloning, Molecular; Oleanolic Acid; Pentacyclic Triterpenes; Squalene; Triterpenes

2020
The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from
    Molecules (Basel, Switzerland), 2021, Nov-11, Volume: 26, Issue:22

    Topics: Alkyl and Aryl Transferases; Amino Acid Substitution; Biosynthetic Pathways; Cyclization; Genes, Plant; Leucine; Maytenus; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Oleanolic Acid; Pentacyclic Triterpenes; Plant Proteins; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Triterpenes

2021