alpha-aminopyridine has been researched along with thiourea in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, CH; Ogle, CW | 1 |
| Gupta, A; Mital, RL; Prakash, L | 1 |
| Kryzhanovskiĭ, GN; Morrison, VV | 1 |
| Baker, CH; Davis, DL; Lindsey, BG; Sutton, ET | 1 |
| Del Soldato, P | 1 |
| Alvarez, EO | 1 |
| Atchison, WD; Lalley, PM; Mellon, WS; Peterson, RE | 1 |
| Ankersen, M; Crider, AM; Ho, B; Liu, S; Stidsen, CE; Tang, C | 1 |
| Maher, D; Mao, C; Pendergrass, S; Tuel-Ahlgren, L; Uckun, FM; Venkatachalam, TK; Zhu, D | 1 |
| Hathway, GJ; Humphrey, PP; Kendrick, KM | 1 |
| D'Cruz, OJ; Mao, C; Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
| Burbach, LR; Cefalu, JS; Cockayne, DA; Ford, AP; Guillon, MA; Ho, MJ; Hu, DQ; Nunn, PA; Zhu, QM | 1 |
| Banks, WA; Crider, AM; Farr, SA; Morley, JE; Niehoff, ML; Sandoval, KE; Witt, KA | 1 |
| Banks, WA; Crider, AM; Farr, SA; Morley, JE; Sandoval, KE; Witt, KA | 2 |
| Chancellor, MB; Hinata, N; Honda, M; Inoue, S; Takenaka, A; Yoshimura, N | 1 |
| Chang, JH; Jeong, BS; Timilshina, M; You, Z | 1 |
| Crider, A; House, A; Sandoval, K; Umbaugh, D; Witt, K | 1 |
| Balamurali, MM; Chanda, K; Maiti, B; Rao, RN; Saikia, AA | 1 |
| Crider, A; Lodholz, E; Polina, J; Sandoval, K; Schober, J; Scott, N; Walters, F; Witt, K | 1 |
| Ahmed, R; Bashir, MA; Choudhary, MI; Rizvi, F; Siddiqui, H; Ullah, S; Zafar, H | 1 |
21 other study(ies) available for alpha-aminopyridine and thiourea
| Article | Year |
|---|---|
Histamine H1- and H2-receptor-mediated gastric microcirculatory effects in the aetiology of stress ulceration in the rat stomach.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; Male; Mast Cells; Metiamide; Microcirculation; Pyrilamine; Rats; Receptors, Histamine; Stomach Ulcer; Stress, Psychological; Thiourea | 1978 |
Condensation products of 2-amino-3-cyano-4,6-disubstituted pyridine with carbon disulfide, thiourea, urea & formamide and their antibacterial activity.
Topics: Aminopyridines; Anti-Bacterial Agents; Carbon Disulfide; Escherichia coli; Formamides; Microbial Sensitivity Tests; Staphylococcus aureus; Thiourea; Urea | 1992 |
[Complex pathogenetic therapy of experimental botulism].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Botulism; Drug Therapy, Combination; Guanylthiourea; Male; Mice; Thiourea | 1987 |
Adrenergic and histaminergic neural interactions in dog paws.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminopyridines; Animals; Blood Pressure; Blood Volume; Capillaries; Dogs; Electric Stimulation; Hindlimb; Metiamide; Pyrilamine; Reference Values; Regional Blood Flow; Sciatic Nerve; Thiourea; Vascular Resistance | 1988 |
Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.
Topics: Aminopyridines; Animals; Atropine; Dimaprit; Drug Interactions; Female; Histamine; Pyridines; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stomach Ulcer; Thiourea | 1984 |
Effects of histamine antagonists injected in the preoptic-anterior hypothalamic area on the prolactin surge induced by estrogen in ovariectomized rats.
Topics: Aminopyridines; Animals; Castration; Circadian Rhythm; Drug Implants; Estrogens; Female; Hypothalamus, Anterior; Metiamide; Preoptic Area; Prolactin; Pyrilamine; Rats; Rats, Inbred Strains; Thiourea | 1984 |
Dithiobiuret-induced muscle weakness in rats: evidence for a prejunctional effect.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Bungarotoxins; Choline; Hemicholinium 3; Male; Muscular Diseases; Neuromuscular Junction; Rats; Rats, Inbred Strains; Thiourea | 1982 |
Nonpeptide somatostatin agonists with sst4 selectivity: synthesis and structure-activity relationships of thioureas.
Topics: Aminopyridines; Animals; Cell Line; Cricetinae; Glaucoma; Humans; Membrane Proteins; Radioligand Assay; Receptors, Somatostatin; Somatostatin; Structure-Activity Relationship; Thiourea | 1998 |
N-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-bromopyridyl)]-thiourea and N'-[2-(1-cyclohexenyl)ethyl]-N'-[2-(5-chloropyridyl)]-thiourea as potent inhibitors of multidrug-resistant human immunodeficiency virus-1.
Topics: Aminopyridines; Anti-HIV Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Thiourea | 1999 |
Evidence that somatostatin sst2 receptors mediate striatal dopamine release.
Topics: 2-Amino-5-phosphonovalerate; Aminopyridines; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Neurotransmitter Agents; Oligopeptides; Peptides, Cyclic; Quinoxalines; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Thiourea | 1999 |
Structural requirements for potent anti-human immunodeficiency virus (HIV) and sperm-immobilizing activities of cyclohexenyl thiourea and urea non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Topics: Aminopyridines; Animals; Anti-HIV Agents; Chemical Phenomena; Chemistry, Physical; Drug Resistance, Microbial; Female; HIV Reverse Transcriptase; HIV-1; Insemination, Artificial; Kinetics; Pregnancy; Quantitative Structure-Activity Relationship; Rabbits; Reverse Transcriptase Inhibitors; Sperm Motility; Spermatocidal Agents; Structure-Activity Relationship; Thiourea; Urea | 2002 |
Selective pharmacological blockade of the TRPV1 receptor suppresses sensory reflexes of the rodent bladder.
Topics: Aminopyridines; Animals; Capsaicin; Female; Male; Mice; Mice, Inbred C57BL; Piperazines; Rats; Rats, Sprague-Dawley; Reflex; Sulfonamides; Thiourea; TRPV Cation Channels; Urinary Bladder | 2009 |
Chronic peripheral administration of somatostatin receptor subtype-4 agonist NNC 26-9100 enhances learning and memory in SAMP8 mice.
Topics: Aminopyridines; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barrier; Brain; Gene Expression Regulation; Male; Maze Learning; Memory; Mice; Peptide Fragments; Receptors, Somatostatin; Thiourea; Time Factors; Tissue Distribution | 2011 |
Somatostatin receptor subtype-4 agonist NNC 26-9100 decreases extracellular and intracellular Aβ₁₋₄₂ trimers.
Topics: Aminopyridines; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Fluid; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Memory; Mice; Mice, Inbred Strains; Molecular Weight; Neprilysin; Nerve Tissue Proteins; Neurons; Nootropic Agents; Peptide Fragments; Receptors, Somatostatin; Solubility; Thiourea | 2012 |
Inhibitory effect of somatostatin receptor subtype-4 agonist NNC 26-9100 on micturition reflex in rats.
Topics: Afferent Pathways; Aminopyridines; Animals; Capsaicin; Dose-Response Relationship, Drug; Female; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Somatostatin; Thiourea; Urination | 2012 |
Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ(42) oligomers via a metalloproteinase-dependent mechanism.
Topics: Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Animals; Blotting, Western; Cerebral Cortex; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Maze Learning; Metalloproteases; Mice; Mice, Transgenic; Receptors, Somatostatin; Thiourea | 2013 |
BJ-2266 ameliorates experimental autoimmune encephalomyelitis through down-regulation of the JAK/STAT signaling pathway.
Topics: Aminopyridines; Animals; Benzamides; Cell Differentiation; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Humans; Interferon-gamma; Interleukin-17; Janus Kinases; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Signal Transduction; STAT Transcription Factors; Th1 Cells; Th17 Cells; Thiourea; Uric Acid | 2017 |
Somatostatin Receptor Subtype-4 Regulates mRNA Expression of Amyloid-Beta Degrading Enzymes and Microglia Mediators of Phagocytosis in Brains of 3xTg-AD Mice.
Topics: Alzheimer Disease; Aminopyridines; Animals; Brain; Catalase; Down-Regulation; Insulysin; Mice, Transgenic; Microglia; Neprilysin; Phagocytosis; Receptors, Somatostatin; RNA, Messenger; Scavenger Receptors, Class A; Sialic Acid Binding Ig-like Lectin 3; Thiourea; Up-Regulation | 2019 |
Diversity-Oriented Synthesis of Thiazolidine-2-imines via Microwave-Assisted One-Pot, Telescopic Approach and Its Interaction with Biomacromolecules.
Topics: Acetylcholinesterase; Aminopyridines; Anticonvulsants; Antineoplastic Agents; Antitubercular Agents; Catalysis; Cholinesterase Inhibitors; Ethylene Dibromide; Humans; Imines; Isothiocyanates; Microwaves; Pyrazines; Pyrimidines; Small Molecule Libraries; Structure-Activity Relationship; Thiazolidines; Thiourea | 2020 |
NNC 26-9100 increases Aβ1-42 phagocytosis, inhibits nitric oxide production and decreases calcium in BV2 microglia cells.
Topics: Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Animals; Calcium; Cell Line; Inflammation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Peptide Fragments; Phagocytosis; Thiourea | 2021 |
Synthesis, density functional theory and kinetic studies of aminopyridine based α-glucosidase inhibitors.
Topics: alpha-Glucosidases; Aminopyridines; Density Functional Theory; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Humans; Kinetics; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiourea | 2023 |