alpha-aminopyridine has been researched along with theophylline in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (52.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meyer, W; Scholz, H | 1 |
| Garrino, MG; Henquin, JC; Hermans, M; Nenquin, M; Paolisso, G | 1 |
| Simpson, LL | 1 |
| Chaudhry, IA; Duncalf, D; Foldes, FF; Goldiner, PL; Nagashima, H; Somogyi, GT; Vizi, ES | 1 |
| Heinemann, U; Schubert, P | 1 |
| Boyd, DK; Evans, DB; Quade, M; Schenden, JA; Weishaar, RE | 1 |
| Dorigo, P; Maragno, I | 1 |
| Brown, L; Erdmann, E | 1 |
| Alkadhi, KA; Brown, TR; Sabouni, MH | 1 |
| Chesebro, JH; Morgan, JP; Pluth, JR; Puga, FJ; Schaff, HV | 1 |
| Le Jemtel, TH; Maskin, CS; Sonnenblick, EH | 1 |
| Hosokawa, T; Kojima, M; Mori, T; Yabuuchi, Y; Yamashita, S | 1 |
| Gundersen, CB; Jenden, DJ | 1 |
| Vignola, AM | 1 |
| Lipworth, B | 1 |
| Bethke, TD; Böhmer, G; Gleiter, CH; Hünnemeyer, A; Lahu, G | 1 |
| Almagro, P; Ancochea, J; Calle, M; López-Campos, JL; Miravitlles, M; Molina, J; Piñera, P; Quintano, JA; Riesco, JA; Simón, A; Soler-Cataluña, JJ; Soriano, JB; Trigueros, JA | 1 |
| Page, CP | 1 |
| Calverley, P; Celli, BR; Chambers, M; Clark, JF; Hawkins, N; Scott, DA; Thompson, JC; Woods, B | 1 |
| Bellon, H; Heigl, T; Hoet, P; Lammertyn, E; Mathyssen, C; Pilette, C; Sacreas, A; Vanaudenaerde, BM; Vandermeulen, E; Verleden, GM; Verleden, SE; Vos, R; Vriens, H | 1 |
| Hashim, Z; Khan, A; Nath, A | 1 |
| Chreifi, G; Do, HT; Li, H; Poulos, TL; Silverman, RB; Wang, HY | 1 |
| Ficker, JH; Graf, J; Jörres, RA; Lucke, T; Nowak, D; Vogelmeier, CF | 1 |
| Chen, DD; Le Grange, JM; Zhang, JN; Zheng, XF; Zhou, LQ; Zhu, XL | 1 |
4 review(s) available for alpha-aminopyridine and theophylline
| Article | Year |
|---|---|
PDE4 inhibitors in COPD--a more selective approach to treatment.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Benzamides; Bronchodilator Agents; Carboxylic Acids; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Humans; Nitriles; Phosphodiesterase Inhibitors; Pneumonia; Pulmonary Disease, Chronic Obstructive; Rolipram; Theophylline; Treatment Outcome | 2004 |
Phosphodiesterase inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Asthma; Benzamides; Bronchodilator Agents; Clinical Trials as Topic; Cyclopropanes; Humans; Molecular Targeted Therapy; Naphthyridines; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Theophylline | 2014 |
Mortality and drug therapy in patients with chronic obstructive pulmonary disease: a network meta-analysis.
Topics: Albuterol; Aminopyridines; Beclomethasone; Benzamides; Benzyl Alcohols; Bronchodilator Agents; Budesonide; Chlorobenzenes; Cyclopropanes; Fluticasone-Salmeterol Drug Combination; Formoterol Fumarate; Glucocorticoids; Humans; Indans; Ipratropium; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Quinolones; Survival Rate; Theophylline; Tiotropium Bromide; Triamcinolone | 2015 |
Chronic obstructive pulmonary disease: Useful medications for patients with recurrent symptoms.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aminopyridines; Benzamides; Bronchodilator Agents; Budesonide; Cyclopropanes; Fluticasone; Formoterol Fumarate; Humans; Ipratropium; Muscarinic Antagonists; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Recurrence; Salmeterol Xinafoate; Theophylline; Tiotropium Bromide | 2016 |
1 trial(s) available for alpha-aminopyridine and theophylline
| Article | Year |
|---|---|
Study investigating pharmacokinetic interaction between theophylline and roflumilast in healthy adults.
Topics: Adolescent; Adult; Aminopyridines; Area Under Curve; Benzamides; Blood Pressure; Body Temperature; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Cytochrome P-450 CYP1A2; Drug Interactions; Female; Half-Life; Heart Rate; Humans; Male; Middle Aged; Phosphodiesterase 4 Inhibitors; Quality Control; Theophylline; Therapeutic Equivalency; Young Adult | 2011 |
20 other study(ies) available for alpha-aminopyridine and theophylline
| Article | Year |
|---|---|
Phosphodiesterase-inhibiting properties of newer inotropic agents.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline | 1986 |
Pharmacological control of 86Rb efflux from mouse pancreatic islets.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Female; In Vitro Techniques; Insulin; Insulin Secretion; Ion Channels; Islets of Langerhans; Kinetics; Mice; Mice, Inbred Strains; Quinine; Radioisotopes; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Ammonium Chloride; Animals; Botulinum Toxins; Calcium; Cholera Toxin; Colforsin; Female; Guanidine; Guanidines; In Vitro Techniques; Methylamines; Mice; Neuromuscular Junction; Neurotoxins; Tetanus Toxin; Theophylline | 1988 |
Modulation of stimulation-evoked release of newly formed acetylcholine from mouse hemidiaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Aminopyridines; Animals; Atropine; Calcium; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Mice; Neuromuscular Junction; Oxotremorine; Tetrodotoxin; Theophylline; Xylazine | 1987 |
Adenosine antagonists combined with 4-aminopyridine cause partial recovery of synaptic transmission in low Ca media.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Deaminase; Aminopyridines; Animals; Calcium; Electric Stimulation; Hippocampus; In Vitro Techniques; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1988 |
Studies aimed at elucidating the mechanism of action of CI-914, a new cardiotonic agent.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dogs; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Mitochondria, Heart; Myocardial Contraction; Myocardium; Ouabain; Papaverine; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Rabbits; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Theophylline | 1985 |
Interaction of amrinone with endogenous adenosine in guinea-pig atria.
Topics: Adenosine; Adenosine Deaminase; Aminopyridines; Amrinone; Animals; Cardiac Glycosides; Cardiotonic Agents; Dipyridamole; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Reserpine; Theophylline | 1986 |
Concentration-response curves of positive inotropic agents before and after ouabain pretreatment.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Metaproterenol; Myocardial Contraction; Ouabain; Papillary Muscles; Phenylephrine; Stimulation, Chemical; Theophylline | 1985 |
Inhibitory effect of adenosine on transmission in sympathetic ganglia.
Topics: 2-Chloroadenosine; 4-Aminopyridine; Action Potentials; Adenosine; Aminopyridines; Animals; Dipyridamole; Electric Stimulation; Female; Ganglia, Sympathetic; In Vitro Techniques; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1984 |
Intracellular calcium transients in human working myocardium as detected with aequorin.
Topics: Aequorin; Aminopyridines; Amrinone; Calcium; Culture Techniques; Digitalis Glycosides; Humans; Ion Channels; Isoproterenol; Luminescent Proteins; Myocardial Contraction; Myocardium; Papillary Muscles; Theophylline; Time Factors | 1984 |
Inotropic drugs for treatment of the failing heart.
Topics: Aminophylline; Aminopyridines; Amrinone; Cardiotonic Agents; Catecholamines; Digitalis Glycosides; Glucagon; Heart Failure; Hemodynamics; Humans; Milrinone; Myocardial Contraction; Pyridones; Receptors, Adrenergic, beta; Theophylline | 1984 |
In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Cats; Dobutamine; Dogs; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phentolamine; Pindolol; Pyrazines; Quinolines; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase; Theophylline | 1984 |
Studies of the effects of agents which alter calcium metabolism on acetylcholine turnover in the rat diaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Bungarotoxins; Calcimycin; Calcium; Diaphragm; Dinitrophenols; Guanidine; Guanidines; In Vitro Techniques; Lanthanum; Male; Ouabain; Rats; Tetraethylammonium Compounds; Theophylline | 1981 |
Phosphodiesterase type 4 inhibitors for asthma: a real breakthrough or just expensive theophylline?
Topics: Aminopyridines; Asthma; Benzamides; Cyclopropanes; Humans; Phosphodiesterase Inhibitors; Randomized Controlled Trials as Topic; Theophylline | 2006 |
Spanish COPD Guidelines (GesEPOC): pharmacological treatment of stable COPD. Spanish Society of Pulmonology and Thoracic Surgery.
Topics: Adrenal Cortex Hormones; alpha 1-Antitrypsin; Aminopyridines; Anti-Bacterial Agents; Asthma; Benzamides; Bronchitis; Bronchodilator Agents; Chronic Disease; Comorbidity; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Expectorants; Humans; Phenotype; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Respiratory System Agents; Severity of Illness Index; Spain; Theophylline | 2012 |
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options.
Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome | 2017 |
Is Concomitant Use of Theophylline and Roflumilast Really Contraindicated?
Topics: Aminopyridines; Benzamides; Cyclopropanes; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Theophylline | 2017 |
Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.
Topics: Aminopyridines; Animals; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; Fluorobenzenes; Humans; Mice; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Structure-Activity Relationship; Swine; Theophylline; Verapamil | 2017 |
Medical Treatment of COPD.
Topics: Adrenal Cortex Hormones; Aminopyridines; Benzamides; Biomimetics; Bronchodilator Agents; Cholinergic Antagonists; Cyclopropanes; Germany; Guideline Adherence; Humans; Medical Overuse; Practice Patterns, Physicians'; Pulmonary Disease, Chronic Obstructive; Theophylline; Treatment Outcome | 2018 |
Impacts of anti-inflammatory phosphodiesterase inhibitors on a murine model of chronic pulmonary inflammation.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Cyclopropanes; Disease Models, Animal; Histone Deacetylase 2; Interleukin-8; Lung; Male; Mice, Inbred C57BL; Nicotiana; Pentoxifylline; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Smoke; Smoking; Theophylline; Tumor Necrosis Factor-alpha | 2021 |