alpha-aminopyridine has been researched along with sb 242084 in 171 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (4.09) | 18.2507 |
| 2000's | 77 (45.03) | 29.6817 |
| 2010's | 83 (48.54) | 24.3611 |
| 2020's | 4 (2.34) | 2.80 |
| Authors | Studies |
|---|---|
| Blackburn, TP; Blaney, FE; Bromidge, SM; Clarke, SE; Duckworth, M; Forbes, IT; Ham, P; Kennett, GA; King, FD; Naylor, CB; Thewlis, KM; Wood, MD | 1 |
| Dekeyne, A; Gobert, A; Millan, MJ | 1 |
| Bright, F; Kennett, GA; Trail, B | 1 |
| Dekeyne, A; Girardon, S; Millan, MJ | 1 |
| Heron-Maxwell, CL; O'Neill, MF; Shaw, G | 1 |
| Garavaglia, C; Invernizzi, R; Pozzi, L; Samanin, R | 1 |
| Di Giovanni, G; Di Mascio, M; Di Matteo, V; Esposito, E | 2 |
| Cussac, D; Millan, MJ; Newman-Tancredi, A; Quentric, Y | 1 |
| Barton, CL; Blurton, P; Bristow, LJ; Burkamp, F; Clarkson, R; Hutson, PH; Jay, M | 1 |
| Fletcher, PJ; Grottick, AJ; Higgins, GA | 2 |
| Clifton, PG; Dourish, CT; Lee, MD | 1 |
| Takada, A; Takada, Y; Takahashi, H; Urano, T | 1 |
| Di Giovanni, G; Di Matteo, V; Esposito, E; La Grutta, V | 1 |
| Grottick, AJ; Higgins, GA; Ouagazzal, AM | 1 |
| Corrigall, WA; Grottick, AJ; Higgins, GA | 1 |
| Evans, DC; Hemrick-Luecke, SK | 1 |
| Anheuer, ZE; Bagdy, G; Graf, M; Kantor, S; Modos, EA | 2 |
| Ballard, TM; Higgins, GA; Martin, JR | 1 |
| Clifton, PG; Dourish, CT; Hewitt, KN; Lee, MD | 1 |
| Higgins, GA; Joharchi, N; Martin, JR; Tampakeras, M; Tomkins, DM; Wichmann, J | 1 |
| Acconcia, S; Ceglia, I; Invernizzi, RW; Pozzi, L; Samanin, R | 1 |
| Duxon, MS; Jones, N; King, SM | 1 |
| Barrett, RJ; Sanders-Bush, E; Smith, RL | 1 |
| Hrupka, BJ; Langhans, W; von Meyenburg, C | 1 |
| Carrasco, GA; D'Souza, DN; Damjanoska, KJ; Garcia, F; Haskins, KA; Kindel, GH; Muma, NA; Petersen, BR; Shankaran, M; Van De Kar, LD; Zhang, Y | 1 |
| Breese, GR; Knapp, DJ; Moy, SS; Overstreet, DH | 2 |
| Enderlin, M; Fletcher, PJ; Haman, M; Higgins, GA | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; Bortolozzi, A; Díaz-Mataix, L; Pons, S; Serrats, J | 1 |
| De Deurwaerdère, P; Navailles, S; Porras, G; Spampinato, U | 1 |
| Billinton, A; Duxon, MS; Quinn, LP; Stean, TO; Stratton, SC; Trail, B; Upton, N | 1 |
| Clifton, PG; Hartfield, AW; Moore, NA | 1 |
| Campbell, BM; Merchant, KM | 1 |
| Chintoh, AF; Fletcher, PJ; Higgins, GA; Sinyard, J | 1 |
| Hatanaka, K; Kimura, Y; Koakutsu, A; Maeno, K; Naitou, Y; Shimada, I; Wanibuchi, F; Yamaguchi, T | 1 |
| Bagdy, G; Gerber, K; Graf, M; Halasz, P; Jakus, R; Juhasz, G; Levay, G | 1 |
| Berg, KA; Clarke, WP; De Deurwaerdère, P; Navailles, S; Spampinato, U | 1 |
| Hayashi, A; Kimura, Y; Miyata, K; Sasamata, M; Sonoda, R; Suzuki, M; Takasu, T | 1 |
| Dalley, JW; Glennon, JC; Robbins, TW; Theobald, DE; Winstanley, CA | 1 |
| Hayashi, A; Miyata, K; Sasamata, M; Suzuki, M | 1 |
| Clark, A; Ebling, FJ; Fone, KC; Horan, TL; Joseph, W; Lehnen, K; Patel, A; Schuhler, S; Stratford, E | 1 |
| Greenshaw, A; Hayes, D; Mosher, T | 1 |
| Eckler, JR; Rabin, RA; Rice, KC; Winter, JC | 1 |
| Bagdy, G; Detari, L; Gyongyosi, N; Jakus, R; Kantor, S; Molnar, E; Toth, A | 1 |
| De Deurwaerdère, P; Navailles, S; Spampinato, U | 1 |
| Dai, J; Huang, M; Ichikawa, J; Li, Z; Meltzer, HY; Prus, AJ | 1 |
| Clifton, PG; Dalton, GL; Dourish, CT; Kennett, GA; Lee, MD | 1 |
| Fletcher, PJ; Higgins, GA; Sinyard, J | 1 |
| Gráf, M | 1 |
| Eltayb, A; Schilström, B; Svensson, TH; Wadenberg, ML | 1 |
| Boothman, L; Denk, F; Hirani, E; Raley, J; Sharp, T | 1 |
| Bertaina-Anglade, V; Boyer, PA; la Rochelle, CD; Mocaër, E | 1 |
| Avison, MJ; Deutch, AY; Gore, JC; Gresch, PJ; Hackler, EA; Sanders-Bush, E; Sengupta, S; Turner, GH | 1 |
| Asarian, L; Geary, N; Kopf, BS; Langhans, W | 2 |
| Cunningham, KA; Moison, D; Navailles, S; Spampinato, U | 1 |
| Filip, M; McCreary, AC; Przegaliński, E; Zaniewska, M | 1 |
| Breese, GR; Knapp, DJ; Overstreet, DH | 1 |
| Aizawa, N; Igawa, Y; Ishizuka, O; Mizusawa, H; Nishizawa, O; Ogawa, T | 1 |
| Fletcher, PJ; Higgins, GA; Sinyard, J; Tampakeras, M | 1 |
| Burbassi, S; Cervo, L | 1 |
| Ebiko, M; Ise, SN; Kimura, Y; Mizoguchi, H; Sakurada, S; Watanabe, C; Yonezawa, A; Yoshizumi, M | 1 |
| Boulougouris, V; Glennon, JC; Robbins, TW | 1 |
| Acosta, JI; Neisewander, JL | 1 |
| Dalley, JW; Glennon, JC; Murphy, ER; Pezze, MA; Robbins, TW; Robinson, ES; Theobald, DE | 1 |
| Egashira, N; Fujiwara, M; Iwasaki, K; Koushi, E; Mishima, K; Oishi, R | 1 |
| Al-Shamma, H; Behan, D; Chalmers, D; Chen, W; Espitia, S; Grottick, AJ; Martin, M; Menzaghi, F; Morgan, M; Reyes-Saldana, H; Smith, B; Thomsen, WJ; Whelan, K; Yuskin, D | 1 |
| Gajendiran, M | 1 |
| Asaka, M; Hattori, T; Katsurada, T; Nagai, K; Ohkawara, T; Sadakane, C; Takeda, H | 1 |
| Brooks, L; Fleshner, M; Greenwood, BN; Strong, PV | 1 |
| Kimura, Y; Naitou, Y; Wanibuchi, F; Yamaguchi, T | 1 |
| Cai, L; Hertz, L; Li, B; Nu, W; Peng, L; Zhang, H; Zhang, S | 1 |
| Greenshaw, AJ; Hayes, DJ; Mosher, TM | 1 |
| Cathala, A; Cunningham, KA; Leggio, GM; Moison, D; Piazza, PV; Spampinato, U | 1 |
| Fleshner, M; Greenwood, BN; Strong, PV | 1 |
| Caccia, S; Calcagno, E; Canetta, A; Cervo, L; Fracasso, C; Guzzetti, S; Invernizzi, RW | 1 |
| Ali, U; Liu, J; Liu, X; Wang, S; Wang, T; Wu, ZH; Zhang, QJ | 1 |
| Filip, M; McCreary, AC; Zaniewska, M | 1 |
| Brennum, LT; Cremers, TI; Folgering, JH; Hertel, P; Hogg, S; Mørk, A; Sotty, F | 1 |
| Blier, P; Dremencov, E; El Mansari, M | 1 |
| Fletcher, PJ; Higgins, GA; Isaac, M; Sinyard, J; Slassi, A; Tampakeras, M | 1 |
| Cathala, A; Drago, F; Leggio, GM; Neny, M; Piazza, PV; Rouge-Pont, F; Spampinato, U | 1 |
| Amat, J; Christianson, JP; Fleshner, M; Greenwood, BN; Maier, SF; Paul, ED; Ragole, T; Strong, PV; Watkins, LR | 1 |
| Ali, U; Chen, L; Gui, ZH; Hui, YP; Liu, J; Wang, S; Wang, Y; Wu, ZH; Zhang, QJ | 1 |
| Boulougouris, V; Robbins, TW | 1 |
| Airey, DC; Canal, CE; Gresch, PJ; Olaghere da Silva, UB; Sanders-Bush, E; Watt, EE | 1 |
| Filip, M; McCreary, AC; Wydra, K; Zaniewska, M | 1 |
| Duke, FD; Hamilton, EC; Neisewander, JL; Pentkowski, NS; Pockros, LA; Teer, AP; Thiel, KJ; Weber, SM | 1 |
| Aoyama, T; Chinen, K; Hattori, T; Noguchi, M; Ohno, S; Ro, S; Sadakane, C; Sakurada, T; Takabayashi, H; Yakabi, K | 1 |
| Calcagno, E; Invernizzi, RW | 1 |
| Estrada-González, V; Márquez-Diosdado, MI; Montes-Rodríguez, CJ; Prospéro-García, O; Soria-Gómez, E | 1 |
| Hasegawa, K; Horie, T; Kimura, T; Kinoshita, M; Kita, T; Kuwabara, Y; Nagao, K; Nishi, H; Ono, K; Takanabe-Mori, R | 1 |
| Lominac, KD; McCreary, AC; McIver, G; Szumlinski, KK; Valdivia, PN; Zayara, AE | 1 |
| Cohen, MS; Fantegrossi, WE; Henson, CM; Rice, KC; Simoneau, J; Woods, JH; Zimmerman, SM | 1 |
| Bennett, DJ; Fouad, K; Murray, KC; Rank, MM; Sanelli, L; Vavrek, R | 1 |
| Benaliouad, F; Rompré, PP; Zhornitsky, S | 1 |
| Barnes, NM; Cooper, AJ; Higgs, S | 1 |
| Baker, PM; Ragozzino, ME; Sweeney, JA; Thompson, JL | 1 |
| Creed-Carson, M; Nobrega, JN; Oraha, A | 1 |
| Hajos, M; Kocsis, B; Sörman, E; Wang, D | 1 |
| Bertaina-Anglade, V; Drieu-La-Rochelle, C; Mocaër, E; Seguin, L | 1 |
| Balsam, PD; Fairhurst, S; Kandel, ER; Kellendonk, C; Lipatova, O; Richards, V; Simpson, EH; Ward, RD | 1 |
| Geyer, MA; Powell, SB; Scott, CN; Young, JW; Zhou, X | 1 |
| Berman, BM; Lao, L; Li, A; Ren, K; Tan, M; Xin, J; Zhang, RX; Zhang, Y | 1 |
| Abrahao, KP; Andrade, AL; Goeldner, FO; Souza-Formigoni, ML | 1 |
| Vicente, MA; Zangrossi, H | 1 |
| Harland, AA; Maglathlin, R; McCorvy, JD; Nichols, DE | 1 |
| Akil, H; Capriles, N; Watson, S | 1 |
| Hackett, A; Hanania, T; Paterson, NE; Wetzler, C | 1 |
| Fletcher, PJ; Higgins, GA; Noble, K; Rizos, Z; Rossmann, A; Silenieks, LB; Soko, AD | 1 |
| Glennon, JC; Naylor, CG; Quarta, D; Stolerman, IP | 1 |
| Egashira, N; Fujiwara, M; Iwasaki, K; Mishima, K; Nagao, M; Oishi, R; Okuno, R; Shirakawa, A | 1 |
| Kimura, M; Tanaka, M; Watanabe, Y; Yoshimoto, K | 1 |
| Clifton, PG; Nilsson, SR; Ripley, TL; Somerville, EM | 1 |
| Cooper, DA; Howell, LL; Kimmel, HL; Manvich, DF | 1 |
| Graves, SM; Napier, TC | 1 |
| Amini, E; Jonaidi, H; Taati, M; Zendehdel, M | 1 |
| Fletcher, PJ; Higgins, GA; Soko, AD | 1 |
| De Carolis, L; Nencini, P; Schepisi, C | 1 |
| Gao, L; Han, X; Yuan, L; Zhang, Q; Zhou, W; Zhu, Y | 1 |
| Christianson, JP; Drugan, RC; Flyer, JG; Maier, SF; Watkins, LR | 1 |
| Asaka, M; Hattori, T; Iizuka, S; Muto, S; Nahata, M; Nakagawa, K; Ohnishi, S; Sadakane, C; Saegusa, Y; Takeda, H | 1 |
| Babapour, V; Baghbanzadeh, A; Hassanpour, S; Mokhtarpouriani, K; Pourrahimi, M; Zendehdel, M | 1 |
| Eddy, JB; Good, MA; Humby, T; Reichelt, AC; Wilkinson, LS | 1 |
| Chen, L; Guo, Y; Han, LN; Hui, YP; Li, LB; Liu, J; Sun, YN; Wang, Y; Zhang, L; Zhang, QJ | 1 |
| López-Giménez, JF; Mengod, G; Palacios, JM; Vilaró, MT | 1 |
| Aramini, R; Bisceglia, S; Booth, R; Kasper, J; Kim, MS; Ladd, J; Macfadyen, K; Peris, J; Tikamdas, R | 1 |
| Blier, P; Chenu, F; El Mansari, M; Shim, S | 1 |
| Clifton, PG; Nilsson, SR; Somerville, EM | 1 |
| Harada, Y; Hattori, T; Iizuka, S; Noguchi, M; Ochiai, M; Ro, S; Takayama, K; Yakabi, K | 1 |
| Bagdy, G; Gyertyán, I; Kalmár, L; Kátai, Z; Kostyalik, D; Molnár, E; Pap, D; Petschner, P; Tóthfalusi, L; Vas, S | 1 |
| Abrous, DN; Cathala, A; Devroye, C; Maitre, M; Piazza, PV; Revest, JM; Spampinato, U | 2 |
| Der-Ghazarian, T; Neisewander, JL; Pentkowski, NS; Pockros-Burgess, LA | 1 |
| Burke, MV; McCreary, AC; Nocjar, C; Pehek, EA; Sonneborn, AJ | 1 |
| Bezzina, G; Body, S; Bradshaw, CM; Cheung, TH; Glennon, JC; Hampson, CL; Szabadi, E | 1 |
| Hattori, T; Nahata, M; Nakagawa, K; Ohnishi, S; Okubo, N; Sadakane, C; Saegusa, Y; Takeda, H; Yamada, C | 1 |
| Fletcher, PJ; Higgins, GA; Zeeb, FD | 1 |
| Platt, DM; Rüedi-Bettschen, D; Spealman, RD | 1 |
| Noori, HR; Spanagel, R; Vengeliene, V | 1 |
| Alsiö, J; Dam, SA; Gastambide, F; Mar, AC; Nilsson, SR; Robbins, TW; Tricklebank, M; Wang, RA | 1 |
| Banks, ML; Bauer, CT; Blough, BE; Negus, SS | 1 |
| Corrêa, FM; Joca, SR; Resstel, LB; Scopinho, AA; Stanquini, LA | 1 |
| Christianson, JP; Foilb, AR | 1 |
| Avlar, B; Balsam, PD; Jensen, G; Kahn, JB; Kandel, ER; Simpson, EH | 1 |
| Dong, L; Jiang, Q; Liu, H; Pang, G; Stackman, RW; Tao, X; Wu, X; Zhang, G; Zhang, YM | 1 |
| Bailey, MR; Balsam, PD; Mezias, C; Silver, R; Simpson, EH; Williamson, C; Winiger, V | 1 |
| Beeson, CC; Demireva, EY; Gingrich, JA; Harmon, JL; McOmish, CE; Schnellmann, RG; Wills, LP | 1 |
| Imanishi, T; Kondo, M; Koyama, T; Ohyama, M; Yamauchi, M | 1 |
| Browne, CJ; Fletcher, PJ | 1 |
| Hagino, Y; Ide, S; Ikeda, K; Kamegaya, E; Matsuzawa, M; Mishina, M; Sawada, W; Takamatsu, Y; Yamamoto, H; Yamamoto, T | 1 |
| Bojanowska, E; Drobnik, J; Juszczak, M; Wierucka-Rybak, M; Wolak, M | 1 |
| Anderberg, RH; Banke, E; Berqquist, F; Eerola, K; Gribble, FM; Hansson, C; Lamy, CM; López-Ferreras, L; Nissbrandt, H; Reimann, F; Richard, JE; Skibicka, KP; Wernstedt Asterholm, I | 1 |
| Browne, CJ; Fletcher, PJ; Higgins, GA; Soko, AD; Zeeb, FD | 1 |
| Anastasio, NC; Comer, SD; Cunningham, KA; Fox, RG; Haney, M; Holliday, ED; Moeller, FG; Neelakantan, H; Stutz, SJ | 1 |
| Hattori, T; Matsumoto, C; Nahata, M; Sadakane, C; Takeda, H; Yamada, C | 1 |
| Bailey, MR; Balsam, PD; Bello, EP; Cheer, JF; Chohan, MO; Chun, E; Goldman, O; Jeong, N; Kalmbach, A; Schipani, E; Simpson, EH; Winiger, V | 1 |
| Bagnol, D; Duranton, F; Faton, S; Lajoix, AD; Tassin, JP | 1 |
| Alsiö, J; Bussey, TJ; Dewan, S; Heath, CJ; Nilsson, SRO; Phillips, BU; Robbins, TW; Saksida, LM | 1 |
| Baptista-de-Souza, D; Canto-de-Souza, A; Canto-de-Souza, L; Nunes-de-Souza, RL; Pelarin, V | 1 |
| Griggs, JL; Mathai, ML; Sinnayah, P | 1 |
| Bagdy, G; Bogáthy, E; Kostyalik, D; Petschner, P; Vas, S | 1 |
| de Andrade, TGCS; Hernandes, PM; Sant'Ana, AB; Vicente, MA; Vilela-Costa, HH; Zangrossi, H | 1 |
| Amancio-Belmont, O; Estrada-González, V; Méndez-Díaz, M; Prospéro-García, O; Ruiz-Contreras, AE | 1 |
| Corrêa, FM; Fortaleza, EA; Matthiesen, M; Mendes, LD; Spiacci, A; Zangrossi, H | 1 |
| Dewey, WL; González-Maeso, J; Lippold, KM; Poklis, JL; Sierra, S; Stevens, DL | 1 |
| Andreasen, JT; Kristensen, JL; Odland, AU | 1 |
| Chen, W; Guo, G; Ou, H; Shi, M; Tang, J; Yang, C | 1 |
171 other study(ies) available for alpha-aminopyridine and sb 242084
| Article | Year |
|---|---|
6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]- indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist.
Topics: Aminopyridines; Animals; Blood-Brain Barrier; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Molecular Structure; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists | 1997 |
Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo.
Topics: Aminopyridines; Animals; Dopamine; Ethylamines; Frontal Lobe; Indoles; Kinetics; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Conditioning, Operant; Conflict, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1998 |
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1999 |
5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB.
Topics: Aminopyridines; Amphetamine; Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Female; Fluorobenzenes; Indoles; Mice; Motor Activity; Piperidines; Ritanserin; Serotonin Antagonists | 1999 |
Fluoxetine increases extracellular dopamine in the prefrontal cortex by a mechanism not dependent on serotonin: a comparison with citalopram.
Topics: Aminopyridines; Animals; Biogenic Monoamines; Citalopram; Dopamine; Extracellular Space; Fenclonine; Fluoxetine; Indoles; Injections, Intraperitoneal; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 1999 |
SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system.
Topics: Aminopyridines; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ethylamines; Indoles; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Ventral Tegmental Area | 1999 |
Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin(2C/2B) receptor agonists: a combined in vivo electrophysiological and microdialysis study.
Topics: Aminopyridines; Animals; Dopamine; Indoles; Male; Neostriatum; Neurons; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Ventral Tegmental Area | 2000 |
An innovative method for rapid characterisation of phospholipase C activity: SB242,084 competitively antagonises 5-HT2C receptor-mediated [3H]phosphatidylinositol depletion.
Topics: Aminopyridines; Animals; CHO Cells; Cricetinae; Ergolines; Humans; Indoles; Phosphatidylinositols; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Type C Phospholipases | 2000 |
Activation of mesolimbic dopamine function by phencyclidine is enhanced by 5-HT(2C/2B) receptor antagonists: neurochemical and behavioural studies.
Topics: Aminopyridines; Animals; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Indoles; Limbic System; Male; Motor Activity; Nucleus Accumbens; Phencyclidine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Stimulation, Chemical | 2000 |
Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behavior.
Topics: Aminopyridines; Animals; Catalepsy; Cocaine; Conditioning, Psychological; Ethylamines; Food; Indoles; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement Schedule; Ventral Tegmental Area | 2000 |
Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist and d-fenfluramine on feeding patterns in the rat.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Ethylamines; Feeding Behavior; Fenfluramine; Indoles; Male; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists | 2000 |
Dissociation of systemic and hippocampal modulation of rat locomotor activity by 5-HT(2C) receptors.
Topics: Aminopyridines; Animals; Circadian Rhythm; Drug Administration Routes; Hippocampus; Indoles; Injections, Intraperitoneal; Male; Motor Activity; Neural Pathways; Neurons; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
m-Chlorophenylpiperazine excites non-dopaminergic neurons in the rat substantia nigra and ventral tegmental area by activating serotonin-2C receptors.
Topics: Aminopyridines; Animals; Electrophysiology; gamma-Aminobutyric Acid; Indoles; Male; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Ventral Tegmental Area | 2001 |
Influence of the 5-HT(2C) receptor antagonist SB242,084 on behaviour produced by the 5-HT(2) agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramine.
Topics: Aminopyridines; Analysis of Variance; Animals; Dexfenfluramine; Drug Interactions; Ethylamines; Indoles; Male; Muscle Contraction; Psychomotor Agitation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Activation of 5-HT(2C) receptors reduces the locomotor and rewarding effects of nicotine.
Topics: Aminopyridines; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylamines; Food; Indoles; Injections, Intravenous; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Comparison of the potency of MDL 100,907 and SB 242084 in blocking the serotonin (5-HT)(2) receptor agonist-induced increases in rat serum corticosterone concentrations: evidence for 5-HT(2A) receptor mediation of the HPA axis.
Topics: Aminopyridines; Amphetamines; Animals; Corticosterone; Dose-Response Relationship, Drug; Ethylamines; Fluorobenzenes; Hypothalamo-Hypophyseal System; Indoles; Male; Piperazines; Piperidines; Quipazine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.
Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Fluoxetine; Grooming; Indoles; Interpersonal Relations; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Sertraline | 2001 |
Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety.
Topics: Aminopyridines; Animals; Anxiety; Compulsive Behavior; Conditioning, Operant; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drinking; Emotions; Fear; GABA Modulators; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reflex, Startle; Reinforcement Schedule; Serotonin Antagonists; Taste | 2002 |
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.
Topics: Aminopyridines; Animals; Diet; Dose-Response Relationship, Drug; Ethylamines; Feeding Behavior; Indoles; Mice; Oxadiazoles; Piperazines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Satiety Response; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
An investigation of the role of 5-HT(2C) receptors in modifying ethanol self-administration behaviour.
Topics: Alcohol Drinking; Alcoholism; Aminopyridines; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Dexfenfluramine; Ethanol; Ethylamines; Indoles; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Stimulation of 5-hydroxytryptamine (5-HT(2C) ) receptors in the ventrotegmental area inhibits stress-induced but not basal dopamine release in the rat prefrontal cortex.
Topics: Aminopyridines; Animals; Dopamine; Drug Administration Routes; Ethylamines; Extracellular Space; Indoles; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Restraint, Physical; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Physiological; Ventral Tegmental Area | 2002 |
Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding.
Topics: Aminopyridines; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Fluorobenzenes; Indoles; Male; Motor Activity; Neural Pathways; Piperidines; Quinolines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Self Administration; Serotonin; Serotonin Antagonists | 2002 |
5-HT2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus maze.
Topics: Aminopyridines; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Exploratory Behavior; Fear; Indoles; Male; Maze Learning; Motor Activity; Piperazines; Random Allocation; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2002 |
Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice.
Topics: Aminopyridines; Animals; Conditioning, Operant; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Fluorobenzenes; Indoles; Indophenol; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57BL; Piperazines; Piperidines; Pyridines; Reaction Time; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Evidence that the anorexia induced by lipopolysaccharide is mediated by the 5-HT2C receptor.
Topics: Adrenergic beta-Antagonists; Aminopyridines; Animals; Anorexia; Dopamine Antagonists; Dose-Response Relationship, Drug; Indoles; Lipopolysaccharides; Male; Metoclopramide; Pindolol; Piperidones; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Spiro Compounds; Sulfonamides | 2003 |
Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist.
Topics: Aminopyridines; Animals; Drug Interactions; Ethylamines; Fluorobenzenes; Indoles; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2003 |
A 5-HT1A agonist and a 5-HT2c antagonist reduce social interaction deficit induced by multiple ethanol withdrawals in rats.
Topics: Aminopyridines; Animals; Anxiety; Buspirone; Dose-Response Relationship, Drug; Ethanol; Ethylamines; Indoles; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior; Substance Withdrawal Syndrome | 2003 |
m-CPP-induced self-grooming is mediated by 5-HT2C receptors.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Drug Antagonism; Grooming; Indoles; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists | 2003 |
The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism.
Topics: Aminopyridines; Animals; Dizocilpine Maleate; Drug Interactions; Fluorobenzenes; Impulsive Behavior; Indoles; Male; Motor Activity; Neuroprotective Agents; Piperidines; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists | 2003 |
In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminopyridines; Anesthetics, Local; Animals; Antipsychotic Agents; Benzopyrans; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Immunohistochemistry; In Situ Hybridization; Indoles; Indophenol; Male; Mice; Mice, Inbred C57BL; Microdialysis; Piperidines; Prazosin; Prefrontal Cortex; Quinoxalines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Thiazoles; Time Factors | 2003 |
In vivo evidence that 5-HT2C receptor antagonist but not agonist modulates cocaine-induced dopamine outflow in the rat nucleus accumbens and striatum.
Topics: Aminopyridines; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Electrochemistry; Ethylamines; Extracellular Space; Haloperidol; Indoles; Male; Microdialysis; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Time Factors | 2004 |
LABORAS: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamine; Angiotensin II; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Feeding Behavior; Haloperidol; Indoles; Injections, Intraventricular; Male; Motor Activity; Piperazines; Psychology, Experimental; Psychotropic Drugs; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Serotonergic and histaminergic mechanisms involved in intralipid drinking?
Topics: Aminopyridines; Animals; Cyproheptadine; Dietary Fats; Dose-Response Relationship, Drug; Drinking Behavior; Eating; Histamine; Histamine H1 Antagonists; Hyperphagia; Indoles; Male; Metergoline; Pyrilamine; Rats; Serotonin; Serotonin Antagonists | 2003 |
Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Behavior, Animal; Dentate Gyrus; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; In Situ Hybridization; Indoles; Male; Motor Activity; Prefrontal Cortex; Propionates; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2C; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Thalamus; Ultrasonics; Vocalization, Animal | 2003 |
Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Ethylamines; Indoles; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement Schedule; Self Administration; Serotonin 5-HT2 Receptor Antagonists; Time Factors; Ventral Tegmental Area | 2004 |
Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist.
Topics: Aminopyridines; Animals; Behavior, Animal; Cell Membrane; CHO Cells; Cloning, Molecular; Cricetinae; Depression, Chemical; Dose-Response Relationship, Drug; Hemodynamics; Indazoles; Indoles; Male; Motor Activity; Penile Erection; Phosphatidylinositols; Pyrimidines; Rats; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Synaptic Transmission | 2004 |
5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy.
Topics: Action Potentials; Aminopyridines; Animals; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Epilepsy, Absence; Fluoxetine; Indoles; Injections, Intraperitoneal; Injections, Intraventricular; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens.
Topics: 5,7-Dihydroxytryptamine; Aminopyridines; Animals; CHO Cells; Cricetinae; Dopamine; Dose-Response Relationship, Drug; Ethylamines; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Ligands; Male; Microdialysis; Neostriatum; Neural Inhibition; Neural Pathways; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Antiobesity effect of YM348, a novel 5-HT2C receptor agonist, in Zucker rats.
Topics: Aminopyridines; Animals; Anti-Obesity Agents; Blood Glucose; Body Temperature; Body Weight; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Eating; Energy Intake; Indazoles; Indoles; Insulin; Lipids; Male; Obesity; Rats; Rats, Zucker; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Time Factors; Weight Gain | 2004 |
SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats.
Topics: Alcohol Drinking; Aminopyridines; Animals; Anxiety; Ethanol; Flumazenil; Indoles; Male; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2004 |
5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion.
Topics: 5,7-Dihydroxytryptamine; Aminopyridines; Animals; Conditioning, Operant; Fluorobenzenes; Impulsive Behavior; Indoles; Injections, Intraventricular; Male; Piperidines; Psychomotor Performance; Rats; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Agents; Serotonin Antagonists | 2004 |
Agonist diversity in 5-HT(2C) receptor-mediated weight control in rats.
Topics: Administration, Oral; Aminopyridines; Animals; Appetite Depressants; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabolism; Ethylamines; Feeding Behavior; Indazoles; Indoles; Male; Piperazines; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Agonists; Weight Loss | 2005 |
Involvement of 5-HT receptors in the regulation of food intake in Siberian hamsters.
Topics: Aminopyridines; Analysis of Variance; Animals; Appetite Regulation; Body Composition; Cricetinae; Dose-Response Relationship, Drug; Eating; Energy Metabolism; Feeding Behavior; Female; Fenfluramine; Hypothalamus; Indoles; Phodopus; Photoperiod; Receptor, Serotonin, 5-HT2C; Seasons; Selective Serotonin Reuptake Inhibitors | 2005 |
Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats.
Topics: Aminopyridines; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Indoles; Ligands; Male; Motor Activity; Oxadiazoles; Piperazines; Pyrazines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Time Factors | 2005 |
Serotonergic/glutamatergic interactions: potentiation of phencyclidine-induced stimulus control by citalopram.
Topics: Aminopyridines; Analysis of Variance; Animals; Citalopram; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Indoles; Male; Phencyclidine; Piperazines; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Despite similar anxiolytic potential, the 5-hydroxytryptamine 2C receptor antagonist SB-242084 [6-chloro-5-methyl-1-[2-(2-methylpyrid-3-yloxy)-pyrid-5-yl carbamoyl] indoline] and chlordiazepoxide produced differential effects on electroencephalogram power
Topics: Acoustic Stimulation; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Arousal; Cerebral Cortex; Chlordiazepoxide; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Indoles; Male; Polysomnography; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Sleep; Social Behavior; Stress, Psychological; Theta Rhythm | 2005 |
Clozapine and haloperidol differentially alter the constitutive activity of central serotonin2C receptors in vivo.
Topics: Aminopyridines; Animals; Antipsychotic Agents; Brain; Chromatography, High Pressure Liquid; Clozapine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ethylamines; Haloperidol; Indoles; Male; Microdialysis; Nerve Net; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra | 2006 |
ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens.
Topics: Aminopyridines; Animals; Chromatography, High Pressure Liquid; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Indoles; Male; Microdialysis; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse.
Topics: Aminopyridines; Animals; Feeding Behavior; Female; Indoles; Male; Mice; Mice, Knockout; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Satiety Response; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
The effects of the 5-HT(2C) receptor antagonist SB242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists.
Topics: Aminopyridines; Analgesics, Opioid; Animals; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Motor Activity; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2006 |
5-HT2c receptor activation induces grooming behaviour in rats: possible correlations with obsessive-compulsive disorder.
Topics: Aminopyridines; Animals; Grooming; Indoles; Male; Obsessive-Compulsive Disorder; Piperazines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Antipsychotic-like effect by combined treatment with citalopram and WAY 100635: involvement of the 5-HT2C receptor.
Topics: Aminopyridines; Animals; Antipsychotic Agents; Avoidance Learning; Catalepsy; Citalopram; Dose-Response Relationship, Drug; Indoles; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 2007 |
In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism.
Topics: Action Potentials; Aminopyridines; Animals; Brain Chemistry; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Indoles; Male; Neural Inhibition; Neurons; Picrotoxin; Piperazines; Positron-Emission Tomography; Proto-Oncogene Proteins c-fos; Pyrazines; Pyridines; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Ritanserin; Serotonin | 2006 |
Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model.
Topics: Acetamides; Aminopyridines; Animals; Antidepressive Agents; Avoidance Learning; Helplessness, Learned; Imipramine; Indoles; Male; Melatonin; Rats; Rats, Wistar; Receptors, Melatonin; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2006 |
5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation.
Topics: Aminopyridines; Animals; Anxiety; Behavior, Animal; Carbolines; Indoles; Limbic System; Magnetic Resonance Imaging; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists | 2007 |
Pharmacological, but not genetic, disruptions in 5-HT(2C) receptor function attenuate LPS anorexia in mice.
Topics: Aminopyridines; Animals; Animals, Congenic; Anorexia; Base Sequence; DNA Primers; Eating; Indoles; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2007 |
Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine.
Topics: Aminopyridines; Animals; Cocaine; Dopamine; Ethylamines; Indoles; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Ventral Tegmental Area | 2008 |
Effects of the serotonin 5-HT2A and 5-HT2C receptor ligands on the discriminative stimulus effects of nicotine in rats.
Topics: Aminopyridines; Amphetamines; Animals; Azepines; Azetidines; Behavior, Animal; Brain; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylamines; Fluorobenzenes; Indoles; Ligands; Male; Nicotine; Nicotinic Agonists; Piperidines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Nicotinic; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2007 |
Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats.
Topics: Alcohol Drinking; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Buspirone; Dopamine Antagonists; Ethanol; Flumazenil; GABA Modulators; Haloperidol; Indoles; Naloxone; Narcotic Antagonists; Olanzapine; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin Receptor Agonists; Stress, Physiological; Substance Withdrawal Syndrome | 2007 |
Role of 5-HT receptor antagonists in mediating intracavernous pressure response induced by fluvoxamine in conscious rats.
Topics: Aminopyridines; Animals; Blood Pressure; Dose-Response Relationship, Drug; Fluvoxamine; Indoles; Injections, Intraventricular; Male; Penis; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sexual Dysfunction, Physiological | 2007 |
Opposing effects of 5-HT(2A) and 5-HT(2C) receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test.
Topics: Aminopyridines; Amphetamines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Impulsive Behavior; Indoles; Ketanserin; Male; Mice; Mice, Inbred C57BL; Piperidines; Quinolines; Rats; Reaction Time; Serial Learning; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Species Specificity | 2007 |
Stimulation of serotonin2C receptors influences cocaine-seeking behavior in response to drug-associated stimuli in rats.
Topics: Aminopyridines; Animals; Appetitive Behavior; Association Learning; Cocaine-Related Disorders; Cues; Discrimination Learning; Dose-Response Relationship, Drug; Ethylamines; Extinction, Psychological; Indoles; Male; Motivation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reinforcement Schedule; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sucrose | 2008 |
Ejaculatory response induced by a 5-HT2 receptor agonist m-CPP in rats: differential roles of 5-HT2 receptor subtypes.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Ejaculation; Grooming; Indoles; Injections, Intraperitoneal; Ketanserin; Male; Penile Erection; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2008 |
Dissociable effects of selective 5-HT2A and 5-HT2C receptor antagonists on serial spatial reversal learning in rats.
Topics: Aminopyridines; Animals; Cognition; Conditioning, Operant; Discrimination Learning; Fluorobenzenes; Indoles; Male; Piperidines; Psychomotor Performance; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement Schedule; Reversal Learning; Serotonin Antagonists; Space Perception | 2008 |
Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in rats.
Topics: Aminopyridines; Animals; Behavior, Addictive; Cocaine; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Indoles; Male; Motor Activity; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Self Administration | 2007 |
Opposing roles for 5-HT2A and 5-HT2C receptors in the nucleus accumbens on inhibitory response control in the 5-choice serial reaction time task.
Topics: Aminopyridines; Animals; Attention; Brain Chemistry; Cerebral Cortex; Choice Behavior; Dose-Response Relationship, Drug; Fluorobenzenes; Impulsive Behavior; Indoles; Limbic System; Male; Neural Inhibition; Neuropsychological Tests; Nucleus Accumbens; Piperidines; Rats; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Synaptic Transmission | 2008 |
2,5-Dimethoxy-4-iodoamphetamine (DOI) inhibits Delta9-tetrahydrocannabinol-induced catalepsy-like immobilization in mice.
Topics: Aminopyridines; Amphetamines; Analysis of Variance; Animals; Animals, Outbred Strains; Behavior, Animal; Dose-Response Relationship, Drug; Dronabinol; Freezing Reaction, Cataleptic; Indoles; Injections, Intraperitoneal; Ketanserin; Male; Mice; Pyrazines; Quinoxalines; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Time Factors | 2007 |
Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization.
Topics: Aminopyridines; Animals; Behavior, Animal; Benzazepines; Body Weight; Brain; Cell Line; Dopamine; Eating; Fluorobenzenes; Humans; Indoles; Male; Norepinephrine; Obesity; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2008 |
In vivo evidence for serotonin 5-HT2C receptor-mediated long-lasting excitability of lumbar spinal reflex and its functional interaction with 5-HT1A receptor in the mammalian spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Drug Interactions; Electric Stimulation; Indoles; Lumbosacral Region; Male; Membrane Potentials; Motor Neurons; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord | 2008 |
Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.
Topics: Acylation; Aminopyridines; Animals; Anorexia; Antineoplastic Agents; Body Weight; Chalcones; Cisplatin; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Eating; Flavones; Gastric Mucosa; Gastrointestinal Agents; Ghrelin; Hesperidin; Indoles; Male; Oligopeptides; Piperazines; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Ghrelin; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Stomach; Thiophenes; Vagotomy | 2008 |
Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise.
Topics: Aminopyridines; Animals; Anxiety; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Fluvoxamine; Indoles; Male; Motor Activity; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Stress, Psychological | 2008 |
5-HT(2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats.
Topics: alpha-MSH; Aminopyridines; Animals; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Indazoles; Indoles; Lumbosacral Region; Male; Medulla Oblongata; Neural Pathways; Oxytocin; Penile Erection; Penis; Peptides, Cyclic; Piperazines; Pressure; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Urea | 2008 |
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Astrocytes; Butadienes; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Fluoxetine; Gene Expression; Indoles; Maleimides; Mice; Nitriles; Phosphorylation; Piperidines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Quinazolines; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Signal Transduction; Substrate Specificity; Transcriptional Activation; Tyrphostins; Up-Regulation; Urea | 2008 |
Differential effects of 5-HT2C receptor activation by WAY 161503 on nicotine-induced place conditioning and locomotor activity in rats.
Topics: Aminopyridines; Amphetamine; Animals; Conditioning, Operant; Dopamine Agents; Dose-Response Relationship, Drug; Indoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Nicotine; Nicotinic Agonists; Pyrazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2009 |
Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens.
Topics: Aminopyridines; Analysis of Variance; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Ethylamines; Indoles; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2009 |
The effects of the selective 5-HT(2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats.
Topics: Aminopyridines; Animals; Anxiety; Escape Reaction; Freezing Reaction, Cataleptic; Helplessness, Learned; Indoles; Injections, Intraperitoneal; Male; Piperazines; Pyrazines; Rats; Rats, Inbred F344; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological | 2009 |
Enhancement of cortical extracellular 5-HT by 5-HT1A and 5-HT2C receptor blockade restores the antidepressant-like effect of citalopram in non-responder mice.
Topics: Aminopyridines; Analysis of Variance; Animals; Antidepressive Agents; Cerebral Cortex; Citalopram; Drug Interactions; Exploratory Behavior; Extracellular Fluid; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Piperazines; Pyridines; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2009 |
Subthalamic neurons show increased firing to 5-HT2C receptor activation in 6-hydroxydopamine-lesioned rats.
Topics: Action Potentials; Aminopyridines; Analysis of Variance; Animals; Immunohistochemistry; Indoles; Male; Microelectrodes; Neurons; Oxidopamine; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Subthalamic Nucleus | 2009 |
Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats.
Topics: Aminopyridines; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Fluorobenzenes; Indoles; Male; Motor Activity; Nicotine; Nicotinic Agonists; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2009 |
Relevance of dorsal raphe nucleus firing in serotonin 5-HT(2C) receptor blockade-induced augmentation of SSRIs effects.
Topics: Action Potentials; Aminopyridines; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Fluorobenzenes; Indoles; Male; Microdialysis; Neurons; Piperidines; Protein Binding; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tritium | 2009 |
Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area.
Topics: Action Potentials; Aminopyridines; Analysis of Variance; Animals; Catheterization; Citalopram; Dopamine; Indoles; Male; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Ventral Tegmental Area | 2009 |
Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice.
Topics: Aminopyridines; Animals; Benzazepines; Dexfenfluramine; Eating; Ethylamines; Feeding Behavior; Indoles; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naphthyridines; Piperazines; Pyrazines; Quinoxalines; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist.
Topics: Aminopyridines; Analgesics, Opioid; Animals; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Ethylamines; Extracellular Space; Haloperidol; Indoles; Male; Microdialysis; Microinjections; Morphinans; Neural Pathways; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Serotonin 2C receptor signaling in a diffuse neuronal network is necessary for LPS anorexia.
Topics: Aminopyridines; Animals; Anorexia; Brain; Central Nervous System Agents; Darkness; Eating; Indoles; Lipopolysaccharides; Male; Neural Pathways; Neurons; Photoperiod; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Signal Transduction; Time Factors | 2010 |
5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amygdala; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Disease Models, Animal; Electroshock; Indoles; Microdialysis; Rats; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior; Stress Disorders, Traumatic | 2010 |
Unilateral lesion of the nigrostriatal pathway decreases the response of interneurons in medial prefrontal cortex to 5-HT 2A/2C receptor stimulation in the rat.
Topics: Action Potentials; Adrenergic Agents; Aminopyridines; Amphetamines; Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Dopamine Agonists; Dose-Response Relationship, Drug; Indoles; Interneurons; Male; Neural Pathways; Oxidopamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents; Substantia Nigra; Tyrosine 3-Monooxygenase | 2010 |
Enhancement of spatial reversal learning by 5-HT2C receptor antagonism is neuroanatomically specific.
Topics: Aminopyridines; Analysis of Variance; Animals; Brain; Brain Mapping; Conditioning, Operant; Dose-Response Relationship, Drug; Fluorobenzenes; Indoles; Male; Piperidines; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement Schedule; Reversal Learning; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Space Perception; Time Factors | 2010 |
The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen.
Topics: Aminopyridines; Amphetamines; Animals; Autoradiography; Behavior, Animal; Binding Sites; Blotting, Western; Brain; Dose-Response Relationship, Drug; Drug Partial Agonism; Early Growth Response Protein 1; Early Growth Response Protein 2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Hallucinogens; Head Movements; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Pyridines; Receptor, Serotonin, 5-HT2C; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Type C Phospholipases | 2010 |
Differential effects of serotonin (5-HT)2 receptor-targeting ligands on locomotor responses to nicotine-repeated treatment.
Topics: Aminopyridines; Amphetamines; Animals; Azepines; Ethylamines; Fluorobenzenes; Indoles; Male; Motor Activity; Nicotine; Nicotinic Agonists; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2010 |
Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior.
Topics: Aminopyridines; Animals; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Extinction, Psychological; Indoles; Male; Prefrontal Cortex; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists | 2010 |
Reduced ghrelin secretion in the hypothalamus of rats due to cisplatin-induced anorexia.
Topics: Aminopyridines; Animals; Anorexia; Antineoplastic Agents; Cisplatin; Down-Regulation; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Eating; Ghrelin; Hypothalamus; Indoles; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Secretory Pathway; Serotonin Antagonists | 2010 |
Strain-dependent serotonin neuron feedback control: role of serotonin 2C receptors.
Topics: Aminopyridines; Animals; Citalopram; Ethylamines; Extracellular Space; Feedback, Physiological; Fenclonine; gamma-Aminobutyric Acid; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Neurons; Raphe Nuclei; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Species Specificity | 2010 |
Oleamide administered into the nucleus accumbens shell regulates feeding behaviour via CB1 and 5-HT2C receptors.
Topics: Aminopyridines; Animals; Eating; Feeding Behavior; Hyperphagia; Hypothalamus; Indoles; Ketanserin; Male; Motor Activity; Nucleus Accumbens; Oleic Acids; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2010 |
Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5.
Topics: 3T3-L1 Cells; Adipocytes; Aminopyridines; Animals; Cell Differentiation; Indoles; Isoenzymes; Ketanserin; Kruppel-Like Transcription Factors; Mice; MicroRNAs; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase | 2010 |
Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Fluorobenzenes; Glutamic Acid; Indoles; Male; Microdialysis; Neuronal Plasticity; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Interaction of 5-HT2A and 5-HT2C receptors in R(-)-2,5-dimethoxy-4-iodoamphetamine-elicited head twitch behavior in mice.
Topics: Aminopyridines; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Ethylamines; Fluorobenzenes; Hallucinogens; Head; Indoles; Ketanserin; Male; Mice; Mice, Inbred Strains; Movement; Piperidines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Spiro Compounds; Sulfonamides | 2010 |
Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors.
Topics: Aminopyridines; Animals; Cordotomy; Electromyography; Female; Gait Disorders, Neurologic; Hindlimb; Indoles; Injections, Spinal; Locomotion; Muscle Hypotonia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Recovery of Function; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord Injuries; Tail | 2010 |
Evidence that the reward attenuating effect of the D1-like antagonist, SCH-23390, is not mediated by its agonist action at the 5-HT2c receptors.
Topics: Aminopyridines; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Indoles; Male; Piperazines; Pyrazines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2C; Reward; Serotonin Receptor Agonists | 2011 |
Reversal of sibutramine-induced anorexia with a selective 5-HT(2C) receptor antagonist.
Topics: Aminopyridines; Animals; Anorexia; Appetite Depressants; Behavior, Animal; Cyclobutanes; Dose-Response Relationship, Drug; Indoles; Male; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Differential effects of 5-HT(2A) and 5-HT(2C) receptor blockade on strategy-switching.
Topics: Adrenergic alpha-Antagonists; Aminopyridines; Animals; Choice Behavior; Cues; Decision Making; Discrimination, Psychological; Indoles; Ketanserin; Learning; Male; Maze Learning; Photic Stimulation; Prazosin; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists | 2011 |
Effects of 5-HT(2A) and 5-HT(2C) receptor antagonists on acute and chronic dyskinetic effects induced by haloperidol in rats.
Topics: Aminopyridines; Animals; Antipsychotic Agents; Brain Chemistry; Catalepsy; Dyskinesia, Drug-Induced; Fluorobenzenes; Gene Expression Regulation; Haloperidol; Immunohistochemistry; In Situ Hybridization; Indoles; Ketanserin; Male; Mouth; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; RNA, Messenger; Serotonin Antagonists | 2011 |
Control of hippocampal theta rhythm by serotonin: role of 5-HT2c receptors.
Topics: Aminopyridines; Anesthesia; Animals; Brain Stem; Deep Brain Stimulation; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Indoles; Male; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sleep, REM; Theta Rhythm; Time Factors | 2011 |
Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat.
Topics: Acetamides; Aminopyridines; Animals; Antidepressive Agents; Drug Chronotherapy; Indoles; Male; Melatonin; Memory; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Serotonin; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia.
Topics: Affective Symptoms; Aminopyridines; Analysis of Variance; Animals; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Gene Expression; Indoles; Mice; Mice, Transgenic; Motivation; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Reward; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Up-Regulation | 2011 |
The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding.
Topics: Aminopyridines; Analysis of Variance; Animals; Arousal; Attention; Choice Behavior; Dose-Response Relationship, Drug; Exploratory Behavior; Gene Expression; Genotype; Indoles; Inhibition, Psychological; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuropsychological Tests; Reaction Time; Receptors, Dopamine D4; Reflex, Startle; RNA, Messenger; Sensory Gating; Serotonin Antagonists; Statistics as Topic; Time Factors | 2011 |
Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model.
Topics: 5,6-Dihydroxytryptamine; Aminopyridines; Animals; Behavior, Animal; Creatinine; Electroacupuncture; Hyperalgesia; Indoles; Inflammation; Male; Pain; Piperazines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonergic Neurons; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Spinal Cord | 2011 |
Administration of the 5-HT2C receptor antagonist SB-242084 into the nucleus accumbens blocks the expression of ethanol-induced behavioral sensitization in Albino Swiss mice.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Ethanol; Indoles; Male; Mice; Motor Activity; Nucleus Accumbens; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Avoidance Learning; Basolateral Nuclear Complex; Exploratory Behavior; Fluoxetine; Imipramine; Indoles; Male; Maze Learning; Neuropsychological Tests; Pyrazines; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |
A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference.
Topics: Aminopyridines; Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Indoles; Male; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats.
Topics: Aminopyridines; Animals; Cocaine; Conditioning, Psychological; Individuality; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Impulsive action and impulsive choice are mediated by distinct neuropharmacological substrates in rat.
Topics: Adrenergic Uptake Inhibitors; Aminopyridines; Animals; Atomoxetine Hydrochloride; Choice Behavior; Dopamine Uptake Inhibitors; Impulsive Behavior; Indoles; Ketanserin; Male; Methylphenidate; Propylamines; Rats; Rats, Long-Evans; Reaction Time; Serotonin 5-HT2 Receptor Antagonists | 2012 |
The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control.
Topics: Aminopyridines; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Choice Behavior; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Administration Routes; Eating; Feeding Behavior; Impulsive Behavior; Indoles; Male; Motor Activity; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement, Psychology; Rotarod Performance Test; Self Administration; Serotonin Receptor Agonists | 2012 |
Serotonin antagonists in the five-choice serial reaction time task and their interactions with nicotine.
Topics: Aminopyridines; Animals; Attention; Choice Behavior; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Male; Nicotine; Nicotinic Agonists; Piperazines; Pyridines; Rats; Rats, Inbred Strains; Serotonin Antagonists | 2012 |
Role of 5-hydroxytryptamine2C receptors in marble-burying behavior in mice.
Topics: Aminopyridines; Amphetamines; Animals; Behavior, Animal; Fluoxetine; Indoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Paroxetine; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior.
Topics: Alcohol Drinking; Aminopyridines; Analysis of Variance; Animals; Biogenic Monoamines; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Disease Models, Animal; Ethanol; Gene Expression Regulation; Indoles; Male; Mice; Mice, Inbred C57BL; Microdialysis; Microinjections; Nucleus Accumbens; Piperidines; Raphe Nuclei; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine; RNA, Messenger; Serotonin Agents; Sulfonamides | 2012 |
Reduced activity at the 5-HT(2C) receptor enhances reversal learning by decreasing the influence of previously non-rewarded associations.
Topics: Aminopyridines; Animals; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Serotonin, 5-HT2C; Reversal Learning; Reward; Serotonin 5-HT2 Receptor Antagonists; Time Factors | 2012 |
The serotonin 2C receptor antagonist SB 242084 exhibits abuse-related effects typical of stimulants in squirrel monkeys.
Topics: Aminopyridines; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Drug Synergism; Indoles; Male; Receptor, Serotonin, 5-HT2C; Saimiri; Self Administration; Serotonin 5-HT2 Receptor Antagonists; Substance-Related Disorders | 2012 |
SB 206553, a putative 5-HT2C inverse agonist, attenuates methamphetamine-seeking in rats.
Topics: Aminopyridines; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Exploratory Behavior; Indoles; Male; Methamphetamine; Motor Activity; Pyridines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Serotonin Antagonists; Time Factors | 2012 |
The role of central 5-HT(2C) and NMDA receptors on LPS-induced feeding behavior in chickens.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Anorexia; Chickens; Feeding Behavior; Indoles; Lipopolysaccharides; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Impulsive action in the 5-choice serial reaction time test in 5-HT₂c receptor null mutant mice.
Topics: Aminopyridines; Amphetamine; Animals; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Ethylamines; Food Deprivation; Impulsive Behavior; Indoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Reaction Time; Receptor, Serotonin, 5-HT2C; Reinforcement Schedule; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2013 |
Effects of the 5HT2C antagonist SB242084 on the pramipexole-induced potentiation of water contrafreeloading, a putative animal model of compulsive behavior.
Topics: Aminopyridines; Animals; Benzothiazoles; Compulsive Behavior; Disease Models, Animal; Dopamine Agonists; Drinking; Indoles; Male; Pramipexole; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Reinforcement Schedule; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome | 2013 |
Serotonin receptor 2C and insulin secretion.
Topics: Aminopyridines; Animals; Blotting, Western; Cell Line, Tumor; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Gene Expression; Humans; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Palmitic Acid; Piperazines; Receptor, Serotonin, 5-HT2C; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists | 2013 |
Anxiogenic effects of brief swim stress are sensitive to stress history.
Topics: Aminopyridines; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Escape Reaction; Exploratory Behavior; Immobility Response, Tonic; Indoles; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Stress, Physiological; Stress, Psychological; Swimming; Time Factors | 2013 |
Serotonin 2C receptor antagonism ameliorates novelty-induced hypophagia in aged mice.
Topics: Aging; Aminopyridines; Animals; CHO Cells; Cricetinae; Cricetulus; Eating; Exploratory Behavior; Feeding Behavior; HEK293 Cells; Humans; Indoles; Male; Mice; Mice, Inbred C57BL; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological | 2013 |
The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Chickens; Feeding Behavior; Fenclonine; Fluoxetine; Indoles; Injections, Intraventricular; Male; Nociceptin; Opioid Peptides; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2013 |
A novel translational assay of response inhibition and impulsivity: effects of prefrontal cortex lesions, drugs used in ADHD, and serotonin 2C receptor antagonism.
Topics: Aminopyridines; Animals; Atomoxetine Hydrochloride; Disease Models, Animal; Impulsive Behavior; Indoles; Inhibition, Psychological; Male; Methylphenidate; Mice; Prefrontal Cortex; Propylamines; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2013 |
The response of juxtacellular labeled GABA interneurons in the basolateral amygdaloid nucleus anterior part to 5-HT₂A/₂C receptor activation is decreased in rats with 6-hydroxydopamine lesions.
Topics: Action Potentials; Aminopyridines; Amphetamines; Amygdala; Animals; GABA-A Receptor Antagonists; GABAergic Neurons; Glutamate Decarboxylase; Indoles; Interneurons; Male; Microinjections; Oxidopamine; Picrotoxin; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sesterterpenes; Substantia Nigra | 2013 |
Multiple conformations of 5-HT2A and 5-HT 2C receptors in rat brain: an autoradiographic study with [125I](±)DOI.
Topics: Aminopyridines; Animals; Autoradiography; Brain; Ergolines; Indoles; Ketanserin; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin | 2013 |
The serotonin-2 receptor modulator, (-)-trans-PAT, decreases voluntary ethanol consumption in rats.
Topics: Alcohol Drinking; Aminopyridines; Animals; Female; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Reinforcement, Psychology; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Tetrahydronaphthalenes | 2013 |
Role of melatonin, serotonin 2B, and serotonin 2C receptors in modulating the firing activity of rat dopamine neurons.
Topics: Aminopyridines; Animals; Dopaminergic Neurons; Indoles; Locus Coeruleus; Male; Melatonin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Ventral Tegmental Area | 2014 |
Dissociable effects of 5-HT2C receptor antagonism and genetic inactivation on perseverance and learned non-reward in an egocentric spatial reversal task.
Topics: Aminopyridines; Animals; Behavior, Animal; Choice Behavior; Cognition; Discrimination Learning; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Serotonin, 5-HT2C; Reversal Learning; Reward; Serotonin 5-HT2 Receptor Antagonists; Space Perception; Task Performance and Analysis | 2013 |
Urocortin1-induced anorexia is regulated by activation of the serotonin 2C receptor in the brain.
Topics: Aminopyridines; Animals; Anorexia; Energy Intake; Feeding Behavior; Gene Expression; Hypothalamus; Indoles; Male; Medulla Oblongata; Pro-Opiomelanocortin; Proto-Oncogene Proteins c-fos; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Urocortins | 2014 |
Chronic escitalopram treatment caused dissociative adaptation in serotonin (5-HT) 2C receptor antagonist-induced effects in REM sleep, wake and theta wave activity.
Topics: Adaptation, Physiological; Aminopyridines; Analysis of Variance; Animals; Citalopram; Electroencephalography; Electromyography; Fourier Analysis; Indoles; Male; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sleep, REM; Theta Rhythm; Wakefulness | 2014 |
Serotonin2C receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine.
Topics: Aminopyridines; Animals; Cocaine; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Ethylamines; Indoles; Locomotion; Male; Motor Activity; Nucleus Accumbens; Phosphorylation; Proto-Oncogene Proteins c-fos; Quinpirole; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Serotonin 5-HT2 Receptor Agonists; Synaptic Transmission | 2015 |
Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behavior.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Indoles; Male; Maze Learning; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2014 |
Striatal serotonin 2C receptors decrease nigrostriatal dopamine release by increasing GABA-A receptor tone in the substantia nigra.
Topics: Aminopyridines; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Ethylamines; Glutamate Decarboxylase; Indoles; Male; Microdialysis; Neural Pathways; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, GABA-A; Serotonin Agents; Substantia Nigra | 2014 |
Evidence for a role of 5-HT2C receptors in the motor aspects of performance, but not the efficacy of food reinforcers, in a progressive ratio schedule.
Topics: Aminopyridines; Animals; Ethylamines; Fluorobenzenes; Food; Indoles; Male; Motivation; Piperidines; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Serotonin2C receptor stimulation inhibits cocaine-induced Fos expression and DARPP-32 phosphorylation in the rat striatum independently of dopamine outflow.
Topics: Aminopyridines; Analysis of Variance; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Ethylamines; Indoles; Male; Microdialysis; Oncogene Proteins v-fos; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists; Time Factors | 2015 |
Serotonin 2C receptor contributes to gender differences in stress-induced hypophagia in aged mice.
Topics: Age Factors; Aminopyridines; Animals; Anorexia; Aromatase Inhibitors; Brain; Corticosterone; ERRalpha Estrogen-Related Receptor; Feeding Behavior; Female; Ghrelin; Indoles; Letrozole; Male; Mice; Nitriles; Paraventricular Hypothalamic Nucleus; Phenols; Piperazines; Pyrazines; Pyrazoles; Receptor, Serotonin, 5-HT2C; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sex Factors; Stress, Psychological; Triazoles | 2015 |
The Serotonin 2C Receptor Agonist Lorcaserin Attenuates Intracranial Self-Stimulation and Blocks the Reward-Enhancing Effects of Nicotine.
Topics: Aminopyridines; Animals; Benzazepines; Dorsal Raphe Nucleus; Dose-Response Relationship, Drug; Indoles; Male; Medial Forebrain Bundle; Nicotine; Nicotinic Agonists; Rats, Long-Evans; Receptor, Serotonin, 5-HT2C; Reward; Self Stimulation; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys by direct and indirect activation of 5-HT2C receptors.
Topics: Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Cues; Drug-Seeking Behavior; Ethylamines; Fluoxetine; Indoles; Saimiri; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2015 |
Activation of Melatonin Receptors Reduces Relapse-Like Alcohol Consumption.
Topics: Acetamides; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Aminopyridines; Animals; Choice Behavior; Circadian Rhythm; Disease Models, Animal; Indoles; Male; Melatonin; Motor Activity; Rats, Wistar; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Recurrence; Serotonin 5-HT2 Receptor Antagonists | 2015 |
The role of 5-HT2C receptors in touchscreen visual reversal learning in the rat: a cross-site study.
Topics: Aminopyridines; Animals; Association Learning; Baclofen; Choice Behavior; Indoles; Male; Muscimol; Prefrontal Cortex; Rats; Receptor, Serotonin, 5-HT2C; Reversal Learning; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Role of 5-HT₂C receptors in effects of monoamine releasers on intracranial self-stimulation in rats.
Topics: Adrenergic Uptake Inhibitors; Aminopyridines; Animals; Benzeneacetamides; Biogenic Monoamines; Conditioning, Operant; Electrodes, Implanted; Fenfluramine; Indoles; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Opioid, kappa; Selective Serotonin Reuptake Inhibitors; Self Stimulation; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Prelimbic cortex 5-HT1A and 5-HT2C receptors are involved in the hypophagic effects caused by fluoxetine in fasted rats.
Topics: Aminopyridines; Animals; Benzamides; Dose-Response Relationship, Drug; Eating; Fasting; Fluoxetine; Indoles; Male; Microinjections; Motor Activity; Oxadiazoles; Piperazines; Prefrontal Cortex; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Serotonin 2C receptor antagonist improves fear discrimination and subsequent safety signal recall.
Topics: Aminopyridines; Animals; Conditioning, Psychological; Discrimination, Psychological; Electroshock; Fear; Freezing Reaction, Cataleptic; Indoles; Inhibition, Psychological; Male; Mental Recall; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists | 2016 |
Improving temporal cognition by enhancing motivation.
Topics: Aminopyridines; Animals; Cognition; Conditioning, Operant; Corpus Striatum; Female; Gene Expression Profiling; Indoles; Mice; Mice, Transgenic; Motivation; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Reward | 2015 |
Activation of serotonin 5-HT(2C) receptor suppresses behavioral sensitization and naloxone-precipitated withdrawal symptoms in morphine-dependent mice.
Topics: Aminopyridines; Analgesics, Opioid; Animals; Benzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Locomotion; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Reaction Time; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Substance Withdrawal Syndrome; Time Factors | 2016 |
The effects of pharmacological modulation of the serotonin 2C receptor on goal-directed behavior in mice.
Topics: Aminopyridines; Animals; Choice Behavior; Dose-Response Relationship, Drug; Eating; Female; Goals; Indoles; Male; Mice; Mice, Inbred C57BL; Motivation; Receptor, Serotonin, 5-HT2C; Reward; Serotonin 5-HT2 Receptor Antagonists | 2016 |
5-HT2 Receptor Regulation of Mitochondrial Genes: Unexpected Pharmacological Effects of Agonists and Antagonists.
Topics: Aminopyridines; Animals; Electron Transport Complex I; Female; Gene Expression Regulation; Gene Knockdown Techniques; Indoles; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Piperazines; Pyrazines; Rabbits; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Transcription Factors | 2016 |
Asenapine reduces anxiety-related behaviours in rat conditioned fear stress model.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Benzodiazepines; Buspirone; Clozapine; Conditioning, Classical; Dibenzocycloheptenes; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Fear; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Indoles; Male; Olanzapine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2016 |
Decreased Incentive Motivation Following Knockout or Acute Blockade of the Serotonin Transporter: Role of the 5-HT2C Receptor.
Topics: Aminopyridines; Animals; Citalopram; Conditioning, Classical; Conditioning, Operant; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motivation; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Saccharin; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sweetening Agents | 2016 |
Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT
Topics: Acetamides; Aminopyridines; Anhedonia; Animals; Dendrites; Indoles; Mice; Mice, Knockout; Olfactory Bulb; Protein Subunits; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Serotonin 5-HT2 Receptor Antagonists; Social Behavior; Social Isolation; Stress, Psychological | 2017 |
The inhibitory effect of combination treatment with leptin and cannabinoid CB1 receptor agonist on food intake and body weight gain is mediated by serotonin 1B and 2C receptors.
Topics: Aminopyridines; Animals; Cannabinoid Receptor Agonists; Drug Synergism; Eating; Indoles; Leptin; Male; Oxadiazoles; Piperazines; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Weight Gain | 2016 |
Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight.
Topics: Aminopyridines; Animals; Anorexia; Appetite; Body Weight; Dorsal Raphe Nucleus; Exenatide; Feeding Behavior; Fenclonine; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hypoglycemic Agents; Indoles; Liraglutide; Male; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Venoms; Weight Loss | 2017 |
Effects of 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Conditioning, Operant; Fluorobenzenes; Indoles; Male; Methylphenidate; Piperazines; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2017 |
Lorcaserin Suppresses Oxycodone Self-Administration and Relapse Vulnerability in Rats.
Topics: Aminopyridines; Animals; Behavior, Animal; Benzazepines; Conditioning, Operant; Cues; Indoles; Male; Opioid-Related Disorders; Oxycodone; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2017 |
Psychological stress in aged female mice causes acute hypophagia independent of central serotonin 2C receptor activation.
Topics: Aminopyridines; Animals; Corticosterone; Drugs, Chinese Herbal; Feeding Behavior; Female; Ghrelin; Indoles; Male; Mice; Mice, Inbred C57BL; Receptor, Serotonin, 5-HT2C; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological | 2017 |
An Interaction between Serotonin Receptor Signaling and Dopamine Enhances Goal-Directed Vigor and Persistence in Mice.
Topics: Aminopyridines; Animals; Apathy; Brain; Dopamine; Female; Indoles; Male; Mice; Mice, Inbred C57BL; Motivation; Receptor, Serotonin, 5-HT2C; Reward; Signal Transduction | 2018 |
5-HT
Topics: Aminopyridines; Amphetamine; Animals; Arcuate Nucleus of Hypothalamus; Central Nervous System Stimulants; Eating; Feeding Behavior; Food Deprivation; Indoles; Male; Motivation; Motor Activity; Piperazines; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reward; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Ventral Tegmental Area | 2018 |
Selective effects of 5-HT2C receptor modulation on performance of a novel valence-probe visual discrimination task and probabilistic reversal learning in mice.
Topics: Aminopyridines; Animals; Azepines; Depressive Disorder, Major; Discrimination Learning; Indoles; Male; Mice; Probability Learning; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Reversal Learning; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Task Performance and Analysis; Visual Perception | 2018 |
Interplay between 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fear; Indoles; Male; Mice; Microinjections; Nociception; Pain Measurement; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2018 |
Caralluma fimbriata extract activity involves the 5-HT2c receptor in PWS Snord116 deletion mouse model.
Topics: Aminopyridines; Animals; Apocynaceae; Appetite Depressants; Chromosome Deletion; Disease Models, Animal; Eating; Female; Gene Deletion; Humans; Hypothalamus; Indoles; Male; Mice, Inbred C57BL; Phenotype; Phytotherapy; Plant Extracts; Prader-Willi Syndrome; Random Allocation; Receptor, Serotonin, 5-HT2C; RNA, Small Nucleolar; Serotonin 5-HT2 Receptor Antagonists | 2018 |
Blockade of Serotonin 2C Receptors with SB-242084 Moderates Reduced Locomotor Activity and Rearing by Cannabinoid 1 Receptor Antagonist AM-251.
Topics: Aminopyridines; Animals; Behavior, Animal; Cannabinoid Receptor Antagonists; Exploratory Behavior; Indoles; Locomotion; Male; Maze Learning; Piperidines; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Social Behavior | 2019 |
Role of 5-HT2C receptors of the dorsal hippocampus in the modulation of anxiety- and panic-related defensive responses in rats.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Ethylamines; Hippocampus; Imipramine; Indoles; Male; Maze Learning; Microinjections; Panic; Piperazines; Punishment; Pyrazines; Rats; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists | 2019 |
CB1R mediates oleamide's reward while 5HT2cR mediates aversion in the nucleus accumbens shell of rats.
Topics: Aminopyridines; Animals; Conditioning, Operant; Extinction, Psychological; Indoles; Male; Nucleus Accumbens; Oleic Acids; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT2C; Reward; Serotonin 5-HT2 Receptor Antagonists | 2019 |
Serotonin 2C receptors in the basolateral amygdala mediate the anxiogenic effect caused by serotonergic activation of the dorsal raphe dorsomedial subnucleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Anxiety; Basolateral Nuclear Complex; Dorsal Raphe Nucleus; Electric Stimulation; Indoles; Kainic Acid; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonergic Neurons; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2020 |
Adjunctive effect of the serotonin 5-HT
Topics: Aminopyridines; Analgesics; Analgesics, Opioid; Animals; Benzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Indoles; Injections, Spinal; Male; Mice; Pain Measurement; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2020 |
Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice.
Topics: Aminopyridines; Amphetamines; Animals; Behavior, Animal; Citalopram; Compulsive Behavior; Disease Models, Animal; Female; Fluorobenzenes; Indoles; Mice; Piperidines; Psilocybin; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Serotonin Antagonists | 2021 |
MK212, a 5-hydroxytryptamine 2C receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus.
Topics: Aminopyridines; Animals; Brain; Dizocilpine Maleate; Hippocampus; Indoles; Mice; Prefrontal Cortex; Prepulse Inhibition; Pyrazines; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate | 2022 |