Compounds > alpha-aminopyridine
Page last updated: 2024-08-21

alpha-aminopyridine and deoxycytidine

alpha-aminopyridine has been researched along with deoxycytidine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Allen, PT; Hernandez, L; Lijinsky, W; Poirier, LA1
Chin, TM; Chung, KY; Hung, FS; Kan, LS; Lin, SB; Tseng, MH1
Ge, Y; Guo, Y; He, M; He, Y; Li, W; Qiao, Z; Ren, S; Sun, L; Wang, X; Yu, Q1
Chen, L; Cress, WD; Kurtyka, CA1
Ajamie, RT; Cai, S; Chan, EM; Cronier, D; de Dios, A; Del Prado, M; Flack, RS; Gelbert, LM; Iversen, P; Kreklau, E; Lallena, MJ; Lin, X; Neubauer, BL; Sanchez-Martinez, C; Torres, R; Wishart, GN; Young, J1
DeNardo, DG; Hawkins, WG; Hegde, S; Herndon, JM; Jiang, H; Knolhoff, BL; Meyer, MA; Nywening, TM; Pachter, JA; Shapiro, IM; Wang-Gillam, A; Weaver, DT; Zhu, Y1
Okamura, H; Sasaki, S; Taniguchi, Y1
Okamura, H; Sasaki, S; Taniguchi, Y; Wang, L1
Dhaliwal, A; Gray, DS; Moghe, PV; Pelka, S1
Chen, X; Dong, T; Ji, J; Kuang, P; Li, J; Liu, J; Liu, T; Liu, Z; Shen, K; Zhang, C; Zhang, L1
Cai, J; Cai, Q; Fang, Y; Huang, H; Li, Z; Liu, P; Ma, S; Su, N; Tian, X; Wang, J; Xia, Y; Zhang, Y1
Campagne, O; Jonchere, B; Liu, J; Northcott, PA; Onar-Thomas, A; Patel, Y; Pribnow, A; Robinson, GW; Robinson, S; Roussel, MF; Smith, KS; Stewart, CF; Wu, G; Xu, K; Yu, J1

Trials

1 trial(s) available for alpha-aminopyridine and deoxycytidine

ArticleYear
A new conditioning regimen with chidamide, cladribine, gemcitabine and busulfan significantly improve the outcome of high-risk or relapsed/refractory non-Hodgkin's lymphomas.
    International journal of cancer, 2021, 12-15, Volume: 149, Issue:12

    Topics: Adolescent; Adult; Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Busulfan; Cladribine; Deoxycytidine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gemcitabine; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Transplantation Conditioning; Transplantation, Autologous; Young Adult

2021

Other Studies

11 other study(ies) available for alpha-aminopyridine and deoxycytidine

ArticleYear
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
    Carcinogenesis, 1989, Volume: 10, Issue:3

    Topics: Aminopyridines; Animals; Carcinogens; Deoxycytidine; DNA; Homocysteine; Liver; Male; Methapyrilene; Methylation; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; S-Adenosylmethionine

1989
Formation of DNA triple helix containing N(4)-(6-aminopyridin-2-yl)-2'-deoxycytidine.
    Journal of biomolecular structure & dynamics, 2001, Volume: 19, Issue:3

    Topics: Aminopyridines; Base Composition; Base Pairing; Base Sequence; Calorimetry; Cations; Circular Dichroism; Deoxycytidine; DNA; Ethidium; Fluorescence; Fluorescent Dyes; Hydrogen Bonding; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Spermine; Temperature

2001
Chidamide, a novel histone deacetylase inhibitor, synergistically enhances gemcitabine cytotoxicity in pancreatic cancer cells.
    Biochemical and biophysical research communications, 2013, Apr-26, Volume: 434, Issue:1

    Topics: Aminopyridines; Antimetabolites, Antineoplastic; Benzamides; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Histone Deacetylase Inhibitors; Humans; Pancreatic Neoplasms; Up-Regulation

2013
E2F inhibition synergizes with paclitaxel in lung cancer cell lines.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Deoxycytidine; Drug Synergism; E2F3 Transcription Factor; Gemcitabine; Humans; Hydroxyquinolines; Inhibitory Concentration 50; Lung Neoplasms; Paclitaxel; RNA, Small Interfering; Small Cell Lung Carcinoma

2014
Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine.
    Investigational new drugs, 2014, Volume: 32, Issue:5

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Deoxycytidine; Drug Therapy, Combination; Female; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Humans; Mice; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Retinoblastoma Protein; Tumor Burden; Xenograft Model Antitumor Assays

2014
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
    Nature medicine, 2016, Volume: 22, Issue:8

    Topics: Aminopyridines; Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Cell Proliferation; Deoxycytidine; Disease Models, Animal; Disease Progression; Fibrosis; Focal Adhesion Protein-Tyrosine Kinases; Gemcitabine; Humans; Immunoblotting; Immunohistochemistry; Immunotherapy; Immunotherapy, Adoptive; Mice; Pancreatic Neoplasms; Programmed Cell Death 1 Receptor; Reverse Transcriptase Polymerase Chain Reaction; Tumor Escape; Tumor Microenvironment

2016
Aminopyridinyl-Pseudodeoxycytidine Derivatives Selectively Stabilize Antiparallel Triplex DNA with Multiple CG Inversion Sites.
    Angewandte Chemie (International ed. in English), 2016, 09-26, Volume: 55, Issue:40

    Topics: Aminopyridines; Base Pairing; Deoxycytidine; DNA; Fluorescein-5-isothiocyanate; HeLa Cells; Humans; Hydrogen Bonding; Kinetics; Microscopy, Fluorescence; Nucleic Acid Conformation; Nucleic Acid Hybridization; Promoter Regions, Genetic; Telomerase

2016
Modification of the aminopyridine unit of 2'-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences.
    Nucleic acids research, 2018, 09-28, Volume: 46, Issue:17

    Topics: Aminopyridines; Base Composition; Base Pairing; Base Sequence; Binding Sites; Cell-Free System; Cyclin D1; Deoxycytidine; DNA; Gene Expression Regulation; Humans; Kinetics; Models, Molecular; Nucleosides; Promoter Regions, Genetic; Purines; Telomerase

2018
Engineering Lineage Potency and Plasticity of Stem Cells using Epigenetic Molecules.
    Scientific reports, 2018, 11-02, Volume: 8, Issue:1

    Topics: Aged; Aminopyridines; Benzamides; Cell Engineering; Cell Line; Cell Lineage; Cell Plasticity; Cell Proliferation; Deoxycytidine; Epigenesis, Genetic; Gemcitabine; Humans; Mesenchymal Stem Cells; Osteogenesis; Primary Cell Culture; Small Molecule Libraries

2018
Comparison of chidamide-contained treatment modalities versus chemotherapy in the second-line treatment for relapsed or refractory peripheral T-cell lymphoma.
    Leukemia research, 2021, Volume: 111

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gemcitabine; Humans; Lymphoma, T-Cell, Peripheral; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Platinum; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate

2021
Combination of Ribociclib and Gemcitabine for the Treatment of Medulloblastoma.
    Molecular cancer therapeutics, 2022, 08-02, Volume: 21, Issue:8

    Topics: Aminopyridines; Animals; Cerebellar Neoplasms; Child; Deoxycytidine; Gemcitabine; Humans; Medulloblastoma; Mice; Purines

2022