alpha-aminopyridine has been researched along with benzoxazoles in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (90.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bamberger, DL; Fisher, TE; Goldman, ME; Hoffman, JM; Jones, JH; Rooney, CS; Saari, WS; Smith, AM; Thomas, CM; Wai, JS | 1 |
| Cho, SY; Ha, JD; Han, SY; Jung, H; Kang, NS; Kim, HR; Koh, JS; Lee, CO; Lee, J; Ryu, JW | 1 |
| Ahn, SH; Cha, HJ; Cho, SY; Ha, JD; Han, SY; Jung, H; Kang, SY; Kim, HR; Koh, JS; Lee, CO; Lee, J; Lee, MO; Ryu, JW | 1 |
| Chae, CH; Cho, SY; Choi, JW; Choi, SU; Ha, JD; Han, SY; Jung, H; Kim, HR; Koh, JS; Lee, CO; Lee, J; Lee, K; Park, CH; Ryu, JW; Yang, J | 1 |
| Bergh, M; Jeppsson, F; Johnström, P; Juréus, A; Neelissen, J; Pyring, D; Sandell, J; Schou, M; Svensson, S; Swahn, BM | 1 |
| Borroni, E; Kilduff, TS; Malherbe, P; Morairty, SR; Moreau, JL; Revel, FG; Valladao, D; Wettstein, JG | 1 |
| Andersson, J; Cselényi, Z; Eriksdotter, M; Farde, L; Forsberg, A; Freund-Levi, Y; Halldin, C; Jeppsson, F; Johnström, P; Julin, P; Juréus, A; Sandell, J; Schou, M; Svensson, S; Swahn, BM; Varnäs, K | 1 |
| Choi, MJ; Hong, SS; Hong, SW; Jung, KH; Kang, NS; Lee, HS; Lee, J; Park, BH; Yun, JI; Zheng, HM | 1 |
| Dou, H; Feng, K; Jiang, X; Li, Z; Wang, T; Zhang, Y; Zhou, F | 1 |
| Chung, HJ; Han, SY; Kim, JH; Kim, YC; Lee, HJ; Lee, J; Park, KR | 1 |
| Furukawa, J; Maehara, S; Ota, T | 1 |
11 other study(ies) available for alpha-aminopyridine and benzoxazoles
| Article | Year |
|---|---|
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogues of 3-aminopyridin-2(1H)-one.
Topics: Aminopyridines; Antiviral Agents; Benzoxazoles; Cells, Cultured; HIV Reverse Transcriptase; HIV-1; Pyridones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 1992 |
Discovery of aminopyridines substituted with benzoxazole as orally active c-Met kinase inhibitors.
Topics: Administration, Oral; Aminopyridines; Animals; Benzoxazoles; Drug Discovery; Models, Molecular; Protein Kinase Inhibitors; Rats; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship | 2010 |
Evaluation of a multi-kinase inhibitor KRC-108 as an anti-tumor agent in vitro and in vivo.
Topics: Administration, Oral; Aminopyridines; Animals; Antineoplastic Agents; Benzoxazoles; Cell Proliferation; Colorectal Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; fms-Like Tyrosine Kinase 3; HT29 Cells; Humans; Inhibitory Concentration 50; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Synthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors.
Topics: Aminopyridines; Antineoplastic Agents; Benzoxazoles; Cell Line, Tumor; Cell Proliferation; Computer Simulation; fms-Like Tyrosine Kinase 3; Humans; Models, Molecular; Proto-Oncogene Proteins c-met; Structure-Activity Relationship | 2012 |
Synthesis and evaluation of pyridylbenzofuran, pyridylbenzothiazole and pyridylbenzoxazole derivatives as ¹⁸F-PET imaging agents for β-amyloid plaques.
Topics: Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Animals; Benzofurans; Benzothiazoles; Benzoxazoles; Brain; Contrast Media; Fluorine Radioisotopes; Humans; Mice; Mice, Transgenic; Positron-Emission Tomography; Radiopharmaceuticals; Structure-Activity Relationship | 2012 |
Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone.
Topics: Aminopyridines; Animals; Benzoxazoles; Dose-Response Relationship, Drug; GABA Agonists; Male; Naphthyridines; Orexin Receptors; Phenylurea Compounds; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Sulfonamides; Urea | 2012 |
Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aminopyridines; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Benzoxazoles; Binding Sites; Brain; Carbon Radioisotopes; Case-Control Studies; Female; Humans; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Middle Aged; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Radiopharmaceuticals; Sensitivity and Specificity; Thiazoles | 2013 |
KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer.
Topics: Aminopyridines; Angiogenesis Inhibitors; Animals; Antigens, CD34; Apoptosis; Benzoxazoles; Caspase 3; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Human Umbilical Vein Endothelial Cells; Humans; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Molecular Structure; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinase; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Rats; Rats, Sprague-Dawley; Signal Transduction; Stomach Neoplasms; Time Factors; Tissue Culture Techniques; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoxazoles; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Liver Neoplasms; Mice; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Real-Time Polymerase Chain Reaction; Sorafenib; Transfection; Xenograft Model Antitumor Assays | 2015 |
Effects of KRC-108 on the Aurora A activity and growth of colorectal cancer cells.
Topics: Aminopyridines; Apoptosis; Aurora Kinase A; Benzoxazoles; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Enzyme Activation; HT29 Cells; Humans; Lethal Dose 50 | 2015 |
Orexin 2 receptor is involved in orexin A-induced hyperlocomotion in rats.
Topics: Aminopyridines; Animals; Benzoxazoles; Locomotion; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Sulfonamides; Urea | 2019 |