alpha-aminopyridine has been researched along with acetylcysteine in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kammerer, RC; Lampe, MA | 1 |
| Hyun, DH; Kang, JS; Koh, HC; Lee, JE; Lee, KS; Lee, SJ; Shin, IC | 1 |
| Bednarski, PJ; Borlak, J; Keiser, M; Methling, K; Modess, C; Nassif, A; Rosskopf, D; Scheuch, E; Siegmund, W; Terhaag, B | 1 |
| Bednarski, PJ; Methling, K; Oswald, S; Scheuch, E; Siegmund, W | 1 |
| Bellon, H; Heigl, T; Hoet, P; Lammertyn, E; Mathyssen, C; Pilette, C; Sacreas, A; Vanaudenaerde, BM; Vandermeulen, E; Verleden, GM; Verleden, SE; Vos, R; Vriens, H | 1 |
| Berg, T; Borlak, J; van Bömmel, F | 1 |
1 trial(s) available for alpha-aminopyridine and acetylcysteine
| Article | Year |
|---|---|
Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.
Topics: Acetylcysteine; Activation, Metabolic; Administration, Oral; Adult; Aminopyridines; Analgesics; Animals; Arylamine N-Acetyltransferase; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glucuronosyltransferase; Glutathione S-Transferase pi; Healthy Volunteers; Humans; Injections, Intravenous; Madin Darby Canine Kidney Cells; Male; Multidrug Resistance-Associated Protein 2; Pain Threshold; Polymorphism, Genetic; Young Adult | 2015 |
5 other study(ies) available for alpha-aminopyridine and acetylcysteine
| Article | Year |
|---|---|
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole | 1987 |
Fluazinam-induced apoptosis of SH-SY5Y cells is mediated by p53 and Bcl-2 family proteins.
Topics: Acetylcysteine; Aminopyridines; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Electron Transport Complex I; Humans; Mitochondria; Neurons; Oxidative Stress; Pesticides; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Time Factors; Tumor Suppressor Protein p53 | 2011 |
Quantitative LC-MS/MS determination of flupirtine, its N-acetylated and two mercapturic acid derivatives in man.
Topics: Acetylation; Acetylcysteine; Aminopyridines; Chromatography, Liquid; Humans; Male; Mass Spectrometry; Tandem Mass Spectrometry | 2015 |
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options.
Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome | 2017 |
N-acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Antidotes; Biomarkers; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Progression; Drug Therapy, Combination; Female; Glucocorticoids; Glutathione; Hepatocytes; Humans; Infusions, Intravenous; Liver; Liver Transplantation; Male; Middle Aged; Prednisolone; Recovery of Function; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2018 |