alpha-aminopyridine has been researched along with 4-aminopyridine in 666 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 643 (96.55) | 18.7374 |
| 1990's | 5 (0.75) | 18.2507 |
| 2000's | 7 (1.05) | 29.6817 |
| 2010's | 10 (1.50) | 24.3611 |
| 2020's | 1 (0.15) | 2.80 |
| Authors | Studies |
|---|---|
| Rauckman, BS; Roth, B | 1 |
| Boryski, J; Dąbrowska, A; Figlerowicz, M; Guranowski, A; Kołodziej, K; Kraszewski, A; Lipniacki, A; Piasek, A; Pietrusiewicz, ZM; Romanowska, J; Sobkowski, M; Stawiński, J; Szymańska-Michalak, A | 1 |
| Crul, JF; Martinez-Aguirre, E | 1 |
| Lavoie, PA; Scheer, HW | 1 |
| Duval, A; Léoty, C | 1 |
| Hartung, K | 1 |
| Burchiel, KJ; Russell, LC | 1 |
| Kakei, M; Noma, A; Shibasaki, T | 1 |
| Bauer, V | 1 |
| Chused, TM; Wilson, HA | 1 |
| Kuba, K; Kumamoto, E | 1 |
| Junge, D | 1 |
| Bader, CR; Bertrand, D; Dupin, E | 1 |
| Eng, DL; Kocsis, JD; Waxman, SG | 1 |
| Zeise, M | 1 |
| Broun, GR; Cherepnov, VL; Govardovskiĭ, VI | 1 |
| Tapia, R | 2 |
| Berglund, S; Hildebrand, C; Kocsis, JD; Waxman, SG | 1 |
| Gallagher, JP; Shinnick-Gallagher, P; Stevens, DR | 1 |
| Kojima, H; Kuno, M; Yawo, H | 1 |
| Giles, WR; van Ginneken, AC | 1 |
| Mallart, A | 2 |
| Lechat, P; Lemeignan, M; Molgó, J; Peradejordi, F | 1 |
| Hagiwara, S; Schlichter, L; Sidell, N | 1 |
| Angaut-Petit, D; Mallart, A | 1 |
| de Haën, C; Halonen, M; Johnson, DG; Palmer, JD; Smith, PF; Thompson, WJ | 1 |
| Dreyer, F; Penner, R | 2 |
| Bacaner, MB; Brochu, RM; Clay, JR; Shrier, A | 1 |
| Bevan, S; Chiu, SY; Gray, PT; Ritchie, JM | 1 |
| Groves, PM; Sawyer, SF; Tepper, JM; Young, SJ | 1 |
| Dolphin, AC; Scott, RH | 1 |
| Chandra, SV; Lohmann, H; Wiegand, H | 1 |
| Fukuda, J; Kameyama, M; Kasai, H; Yamaguchi, K | 1 |
| Chuman, MA | 1 |
| Cassell, JF; Clark, AL; McLachlan, EM | 1 |
| el-Fakahany, EE; Lai, WS | 1 |
| Lee, KS; Schubert, P | 1 |
| Quastel, DM; Saint, DA | 2 |
| Cheung, RK; Gelfand, EW; Grinstein, S | 1 |
| Golub, SH; Hagiwara, S; Schlichter, LC; Sidell, N; Wright, SC | 1 |
| Ito, I; Maeno, T | 1 |
| Den Hertog, A | 1 |
| Radicheva, N | 1 |
| Gordon, TR; Kocsis, JD; Waxman, SG | 2 |
| Dreyer, F; Penner, R; Petersen, M; Pierau, FK | 1 |
| Elkins, T; Ganetzky, B; Wu, CF | 1 |
| Johansen, J; Kleinhaus, AL | 2 |
| Krnjević, K; Zhang, L | 1 |
| Blaustein, MP; Sorensen, RG | 1 |
| Plant, TD | 1 |
| Zhang, YP; Zheng, W | 1 |
| Cooke, IM; Tazaki, K | 1 |
| Ascher, P; Berwald-Netter, Y; Nowak, L | 1 |
| Gupta, S | 1 |
| Chuman, MA; Davis, FA; Schauf, CL; Stefoski, D | 1 |
| Kato, A; Nakamura, F; Sugimoto, T; Sumino, S; Tomaru, T; Uchida, Y | 1 |
| Davis, FA; Faut, M; Schauf, CL; Stefoski, D | 1 |
| Liepins, A; Younghusband, HB | 1 |
| Ohba, M | 1 |
| Bournaud, R; Mallart, A | 1 |
| Hiraoka, M; Kawano, S | 1 |
| Schauf, CL | 1 |
| Franklin, CL; Gruol, DL | 1 |
| Connor, JA; Hockberger, PE; Tseng, HY | 1 |
| Ichinose, M; Maeno, T; Sawada, M | 2 |
| Eng, DL; Gordon, TR; Kocsis, JD; Waxman, SG | 2 |
| Oyama, Y | 1 |
| Demarest, JR; Finn, AL | 1 |
| Akaike, N; Ikemoto, Y; Ono, K | 1 |
| Garrino, MG; Henquin, JC; Hermans, M; Nenquin, M; Paolisso, G | 1 |
| Dekin, MS; Getting, PA | 1 |
| Jmari, K; Mironneau, C; Mironneau, J | 1 |
| Segal, M | 4 |
| Harris-Warrick, RM; Johnson, BR | 1 |
| Bowe, CM; Hildebrand, C; Kocsis, JD; Waxman, SG | 1 |
| Benabderrazik, M; Gallo-Payet, N; Payet, MD | 1 |
| Imai, S; Ogawa, Y | 1 |
| Brezina, V; Eckert, R; Erxleben, C | 1 |
| Fink, RH; Stephenson, DG | 1 |
| Ashford, ML; Hales, CN; Sturgess, NC | 1 |
| Jonkman, FA; Korstanje, C; Van Kemenade, JE; Van Zwieten, PA | 1 |
| de Graan, PN; Gispen, WH; Heemskerk, FM; Schrama, LH | 1 |
| Castle, NA; Haylett, DG | 1 |
| Baker, M; Bostock, H; Grafe, P; Martius, P | 1 |
| Kawa, K | 1 |
| Ritchie, AK | 1 |
| Storm, JF | 1 |
| Bondy, CA; Gainer, H; Russell, JT | 1 |
| Fitch, FW; Fozzard, HA; Nelson, DJ; Schell, SR | 1 |
| Shuster, MJ; Siegelbaum, SA | 1 |
| Chiu, SY | 1 |
| Aguayo, LG; Albuquerque, EX | 1 |
| Sugimoto, T; Uchida, Y | 1 |
| Bilbaut, A; Hernandez-Nicaise, ML; Leech, CA; Meech, RW | 1 |
| Beech, DJ; Bolton, TB | 1 |
| Aldrich, RW; Hoshi, T | 1 |
| Numann, RE; Wadman, WJ; Wong, RK | 1 |
| Allen, JM; McHale, NG | 1 |
| Martini, M; Rossi, ML | 3 |
| Scholfield, CN; Steel, L | 1 |
| Brown, AM; Marchetti, C; Premont, RT | 1 |
| Anderson, RJ; Chamberlain, WL | 1 |
| Simpson, LL | 2 |
| Hounsgaard, J; Mintz, I | 1 |
| Bossu, JL; Dupont, JL; Feltz, A | 1 |
| Marshall, JM; Wilde, DW | 1 |
| Bondy, CA; Russell, JT | 1 |
| Quandt, FN | 1 |
| Alberts, P; Ogren, VR | 1 |
| Alvarez de Toledo, G; López-Barneo, J | 1 |
| Hirsch, JA; Oertel, D | 1 |
| Massieu, L; Tapia, R | 1 |
| Hudspeth, AJ; Lewis, RS | 2 |
| Folly, G; Vizi, ES; Zimanyi, I | 1 |
| Palmer, JM; Tamura, K; Winkelmann, CK; Wood, JD | 1 |
| Botana, L; Eleno, N; Espinosa, J | 1 |
| Baumann, A; Grupe, A; Pongs, O; Sakmann, B; Seeburg, P; Stocker, M; Stühmer, W | 1 |
| Baskin, EP; Garcia, ML; Heaney, LA; Kaczorowski, GJ; Stein, RB; Wallace, AA; Winquist, RJ | 1 |
| Anderson, AJ; Harvey, AL; Rowan, EG; Strong, PN | 1 |
| Bowyer, JF; Weiner, N | 1 |
| Fierz, W; Hartung, HP; Heininger, K; Schäfer, B; Toyka, KV; Wehling, P | 1 |
| Cook, NS | 1 |
| Brismar, T; Collins, VP | 2 |
| Chiu, SY; Wilson, GF | 1 |
| Boegman, RJ; Metcalf, RH | 1 |
| Gruner, JA | 1 |
| Lynch, G; Muller, D | 1 |
| Adams, WB; Nicholls, JG; Stewart, RR | 2 |
| Cynader, MS; Shaw, C; van Huizen, F; Wilkinson, M | 1 |
| Alkadhi, KA; Hogan, YH | 1 |
| Hoffman, BF; Tseng, GN | 1 |
| Adelman, JP; Christie, MJ; Douglass, J; North, RA | 1 |
| Buyukuysal, RL; Wurtman, RJ | 1 |
| Brazil, OV; Fontana, MD; Pavani, NJ | 1 |
| Nishimura, M; Ohtani, H; Yagasaki, O | 1 |
| Kaschube, M; Zetler, G | 1 |
| Gean, PW; Shinnick-Gallagher, P | 1 |
| Blight, AR | 1 |
| Bidard, JN; Gandolfo, G; Gottesmann, C; Lazdunski, M | 2 |
| Johansen, J; Kleinhaus, AL; Yang, J; Zorumski, CF | 1 |
| Alkon, DL; Coulter, DA; Disterhoft, JF; Kubota, M; Lo Turco, JJ; Moore, JW | 1 |
| Meyer, EM; Otero, DH | 1 |
| Msghina, M; Stjärne, E; Stjärne, L | 1 |
| Magistretti, PJ; Martin, JL | 1 |
| Ebong, OO; Zar, MA | 1 |
| Krnjevic, K; Leblond, J | 1 |
| Røed, A | 1 |
| Caparrotta, L; De Biasi, M; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 1 |
| Dubuc, R; Rossignol, S | 2 |
| Leblanc, N; Ruiz-Petrich, E | 1 |
| Puil, E; Spigelman, I | 1 |
| Miura, RM; Puil, E; Spigelman, I | 1 |
| Makiĭ, EA; Serdiuchenko, IIa | 1 |
| Nijweide, PJ; Ravesloot, JH; Vrijheid-Lammers, T; Ypey, DL | 1 |
| Gilmour, RF; Kaseda, S; Zipes, DP | 1 |
| McCarthy, PW; Reeh, PW; Waddell, PJ | 1 |
| Van der Molen, LG; Van Duijn, B; Ypey, DL | 1 |
| Dolly, JO; Nicholls, DG; Tibbs, GR | 1 |
| Haberly, LB; Hoffman, WH | 1 |
| Barnes, S; Davies, JA; Whitham, EM | 1 |
| Savage, AO | 4 |
| Avoli, M; Perreault, P | 3 |
| Fredholm, BB; Hu, PS | 1 |
| Molgó, J; Pécot-Dechavassine, M; Thesleff, S | 1 |
| Erhardt, W; Hafner, S; Halm, S; von Hegel, G; Wiesner, H | 1 |
| Bures, J; Koroleva, VI; Oitzl, MS | 1 |
| Llinás, RR; MacVicar, BA | 1 |
| Renit-Soria, J; Stinnakre, J; Van Renterghem, C | 1 |
| Chinn, KS; Gillary, HL | 1 |
| Belluzzi, O; Sacchi, O; Wanke, E | 1 |
| Daniel, EE; Jager, LP; Jury, J | 1 |
| el-Fakahany, EE; Lai, WS; Ramkumar, V | 1 |
| Hirst, GD; Johnson, SM; van Helden, DF | 1 |
| Bartschat, DK; Blaustein, MP | 1 |
| Weight, FF; Zbicz, KL | 1 |
| Arispe, N; Quinta-Ferreira, ME; Rojas, E; Soria, B | 1 |
| Berger, SG; Chang Sin-Ren, A; Waser, PG | 1 |
| Harvey, AL; Marshall, DL | 1 |
| Amaki, Y; Futaki, R; Kobayashi, K; Koyama, T; Wada, T | 1 |
| Goh, JW; Kelly, ME; Pennefather, PS | 1 |
| Chaudhry, IA; Duncalf, D; Foldes, FF; Goldiner, PL; Nagashima, H; Somogyi, GT; Vizi, ES | 1 |
| Kitamura, K; Kuriyama, H; Okabe, K | 1 |
| Bowe, CM; Kocsis, JD; Targ, EF; Waxman, SG | 1 |
| Barker, JL; Schaffner, AE; St John, PA | 1 |
| Dunant, Y; Garcia-Segura, LM; Loctin, F; Muller, D; Parducz, A | 1 |
| Kryzhanovskiĭ, GN; Morrison, VV | 2 |
| Lew, MJ; White, TD | 1 |
| Antzelevitch, C; Litovsky, SH | 1 |
| Heinemann, U; Jones, RS | 1 |
| Hatch, RC; Jernigan, AD | 1 |
| Boschero, AC; Delattre, E; Dias, O; Gonçalves, AA; Reis, LC | 1 |
| Clapham, DE; Logothetis, DE | 1 |
| Fu, WM; Lin, RH; Lin-Shiau, SY | 1 |
| Gebremedhin, D; Hadházy, P; Magyar, K | 1 |
| Guan, YY; Quastel, DM; Saint, DA | 1 |
| Altes, U; Baur, AM; Jost, D; Racké, K; Schäfer, J | 1 |
| Arzate, ME; Huxtable, RJ; Pasantes-Morales, H; Quesada, O | 1 |
| Blass, JP; Davidson, M; Davis, KL; Horvath, TB; Mohs, RC; Powchik, P; Zemishlany, Z | 1 |
| Blight, AR; Gruner, JA | 1 |
| Biessels, PT; Damsma, G; De Vries, JB; Horn, AS; Westerink, BH | 1 |
| De Graan, PN; Gispen, WH; Lopes da Silva, FH; Schrama, LH; Wadman, WJ | 1 |
| Robb, R; Schiffman, SS; Simon, SA | 1 |
| Bowe, CM; Veale, K | 1 |
| Booij, LH; Frankhuyzen, AL; Treffers, R | 1 |
| Csicsaky, M; Lohmann, H; Papadopoulos, R; Uhlig, S; Wiegand, H | 1 |
| Heinemann, U; Schubert, P | 1 |
| Arnason, BG; Nelson, DJ; Soliven, B; Szuchet, S | 1 |
| Hikasa, Y; Irie, Y; Ogasawara, S; Takase, K | 1 |
| Borsini, F; Conte, B; Giuliani, S; Lecci, A; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Rafuse, PE; Smith, PA; Zidichouski, JA | 1 |
| Cupera, P; Simurda, J; Simurdová, M | 1 |
| Evangelista, S; Mantovani, P; Santicioli, P; Valoti, M | 1 |
| Gage, PW; Gibb, AJ; Sah, P | 1 |
| Maeno, T; Shibuya, Y | 1 |
| Foldes, FF; Ludvig, N; Nagashima, H; Vizi, ES | 1 |
| Sharma, B | 1 |
| Dos Reis, GA; Nóbrega, AF; Persechini, PM | 1 |
| Bassett, AL; Cameron, JS; Jackson-Burns, DA; Kimura, S; Smith, DB | 1 |
| Gibson, GE; Manger, T | 1 |
| Kaji, R; Sumner, AJ | 1 |
| Avoli, M; Dichter, M; Pirrone, G; Zona, C | 1 |
| Avoli, M; Olivier, A; Perreault, P; Villemure, JG | 1 |
| Bargas, J; Kitai, ST; Surmeier, DJ | 1 |
| Akoev, GN; Krylov, BV; Tsoĭ, SL | 1 |
| Coldwell, MC; Cooper, SM; Hamilton, TC; Howlett, DR; Wilson, C | 1 |
| Kaneps, AJ; Riebold, TW; Schmotzer, WB | 1 |
| Konnerth, A; Orkand, PM; Orkand, RK | 1 |
| Akaike, N; Carpenter, DO; Oyama, Y; Tsuda, Y | 1 |
| Van der Kloot, W | 1 |
| Barrett, EF; Morita, K; Scappaticci, KA | 1 |
| Krieger, C; Sears, TA | 1 |
| Aceves, J; Góngora, JL; Mariscal, S; Sierra, A | 1 |
| Altes, U; Baur, AM; Hobbach, HP; Jost, D; Racké, K; Schäfer, J; Wammack, R | 1 |
| Gollapudi, SV; Gupta, S; Thadepalli, H; Vayuvegula, BS | 1 |
| Giles, WR; Imaizumi, Y | 1 |
| Aguayo, LG; Weight, FF | 1 |
| Brezina, V | 2 |
| Stjärne, L | 1 |
| Hembrough, FB; Hsu, WH; Lu, ZX | 1 |
| Den Hertog, A; Pielkenrood, J; Van den Akker, J | 1 |
| Clark, JD; Hatch, RC; Kitzman, JV; Zahner, JM | 2 |
| Brown, J; Clark, JD; Hatch, RC; Jernigan, AD; Wilson, RC | 1 |
| Chiba, S; Furukawa, Y; Saegusa, K | 3 |
| Olsen, CD; Renecker, LA | 2 |
| Morales, E; Sitges, M; Tapia, R | 1 |
| Chang, CC; Chiou, LC; Hong, SJ; Shieh, BH; Su, MJ | 1 |
| Kápáti, E; Riesz, M; Szporny, L | 1 |
| Genovese, N; Klawans, HL | 1 |
| Khan, AR; Lemeignan, M; Molgo, J | 1 |
| Hopper, DL; Hsu, WH; Schaffer, DD | 1 |
| Hoyo-Vadillo, C; Kubli-Garfias, C; Melgarejo-Salgado, A; Perusquía, M; Rocha-Arrieta, L; Valadez-Rodríguez, J | 1 |
| Campbell, GA; Davis, KL; Haroutunian, V; Kanof, PD; Tsuboyama, GK | 1 |
| Gibb, AJ; Marshall, IG | 1 |
| del Castillo, J; Hernandez, ZM; Morales, M; Smith, DS | 1 |
| Glavinović, MI | 1 |
| Atwood, HL; Parnas, H; Parnas, I; Wojtowicz, JM | 1 |
| de Carolis, AS; Frank, C; Sagratella, S | 1 |
| Freeman, GB; Gibson, GE; Mykytyn, V | 1 |
| Go, ML; Lee, HS | 1 |
| Cruz, F; Montoya, GA; Pezo, P; Roa, J; Villena, F | 1 |
| King, BF; Szurszewski, JH | 1 |
| Benedetti, M; Bernardi, G; Calabresi, P; Mercuri, NB | 1 |
| Cox, RT; Walker, RJ | 1 |
| Lang, B; Newsom-Davis, J; Wray, DW | 1 |
| Bourret, C; Mallart, A; Tabti, N | 1 |
| Kuromaru, O; Sakai, K | 1 |
| Boegman, RJ; Ludwin, SK; Metcalf, R; Riopelle, RJ | 1 |
| Smith, PA; Zidichouski, JA | 1 |
| Harris, JB; Pollard, SL | 1 |
| Ceña, V; García, AG; Gonzalez-Garcia, C; Kirpekar, SM | 1 |
| Kocsis, JD | 1 |
| Dörge, L; Illes, P | 1 |
| Kocsis, JD; Targ, EF | 1 |
| Bikhazi, GB; Flores, C; Foldes, FF | 1 |
| Neel, DS; Parsons, RL; Sharp, NA | 1 |
| Kauffman, JA; Sellin, LC; Siegel, LS; Way, JF | 1 |
| Inoue, M; Matsuo, T; Ogata, N | 1 |
| Guba, F; Keresztes, M; Takács, O | 1 |
| Kremer Hovinga, TK; ter Wee, PM; Uges, DR; van der Geest, S | 1 |
| Joó, F; Mihály, A; Szente, M; Tóth, G | 1 |
| Enomoto, K; Maeno, T | 1 |
| David, G; Selzer, ME; Yaari, Y | 1 |
| Lundh, H; Nilsson, O; Rosén, I | 3 |
| Guerrero, S; Zacharias, J | 1 |
| Albus, H; Voskuyl, RA | 1 |
| Jabbur, SJ; Saadé, N; Wall, PD | 1 |
| Ho, ST; Lee, SH; Yen, MH | 1 |
| Tsuji, S | 1 |
| Ceccarelli, B; Fesce, R; Grohovaz, F; Torri-Tarelli, F | 1 |
| Magnani, M; Mantovani, P; Pepeu, G | 1 |
| Coraboeuf, E; Escande, D; Loisance, D; Planche, C | 1 |
| Egger, MD; Geller, HM; Semba, K | 1 |
| Matsumoto, M; Riker, WK; Takashima, K | 1 |
| Lechat, P; Lemeignan, M; Uchiyama, T | 2 |
| Greene, RW; Haas, HL | 1 |
| Gonzalez, DR; Morales-Aguilera, A | 1 |
| Johns, TR; Kim, YI; Tierney, PC | 1 |
| Kannisto, P; Owman, C; Walles, B | 1 |
| Galatulas, I; Gibelli, N; Supino, R; Zunino, F | 1 |
| Bowe, CM; Kocsis, JD; Waxman, SG | 1 |
| Barnes, E; Davis, KL; Haroutunian, V | 1 |
| Mackintosh, CG | 1 |
| Kita, H; Kita, T; Kitai, ST | 1 |
| Boev, K; Bonev, A; Papasova, M | 1 |
| Mironneau, C; Mironneau, J; Savineau, JP | 1 |
| Böhmer, G; Gouzoulis, E; Löffelholz, K; Raach, M; Schmid, K | 1 |
| Araujo, DM; Collier, B; Rícný, J; Welner, SA | 1 |
| Gaal, G; Harsing, LG; Vizi, ES; Zimanvi, I | 1 |
| Agrawal, R; Daniel, EE | 1 |
| Davis, KL; Hollander, E; Mohs, RC | 1 |
| Dunant, Y | 1 |
| Dubuc, R; Lamarre, Y; Rossignol, S | 1 |
| Barker, JL; Segal, M | 2 |
| Bader, CR; Bernheim, L; Bertrand, D; Dupin, E | 1 |
| Fraser, R; Holloway, CD; Kenyon, CJ | 1 |
| Leonard, RJ; Nakajima, S; Nakajima, Y; Yamaguchi, K | 1 |
| Martinez-Aguirre, E; Sansano, C | 1 |
| Algeo, S; Gay, R; Goldman, S; Lee, R; Morkin, E; Olajos, M | 1 |
| Bayón, A; Possani, LD; Sitges, M | 1 |
| Fujimura, K; Matsuda, Y; Nakamura, M; Yoshida, S | 1 |
| Hilgemann, DW | 1 |
| Eliasson, SG; Meyr, D; Monafo, WW | 1 |
| Davis, JR; Gilmour, RF; Salata, JJ | 1 |
| Gainer, H; Obaid, AL; Salzberg, BM; Wolfe, SA | 1 |
| Arzate, ME; Morán, J; Pasantes-Morales, H | 1 |
| Booth, NH; Brown, J; Clark, JD; Hatch, RC; Jernigan, AD; Lipham, IB; Wilson, RC | 1 |
| Georgiev, A; Mitsov, V | 1 |
| Montoya, GA; Roa, J | 1 |
| Doroshenko, PA; Kostyuk, PG; Martynyuk, AE | 1 |
| Karneta, IM; Mantulo, PM; Serdiuchenko, IIa | 1 |
| Anwyl, R; Lee, WL; Rowan, M | 1 |
| Frossard, N; Muller, F | 1 |
| Dunant, Y; Garcia-Segura, LM; Muller, D | 1 |
| Kigoshi, S; Muramatsu, I; Nishio, M | 1 |
| Coraboeuf, E; Coulombe, A; Deroubaix, E; Escande, D; Faivre, JF | 1 |
| Kato, H; Takata, Y | 1 |
| Kuroki, T; Nose, K; Shibanuma, M | 1 |
| Muller, D | 1 |
| Bassnett, S; Croghan, PC; Duncan, G; Lucas, VA; Stewart, S | 1 |
| Brussaard, AB; De Graan, PN; Gispen, WH; Jork, R; Schrama, LH | 1 |
| Llinás, R; Yarom, Y | 1 |
| Potapov, AA | 1 |
| Agoston, S; Biessels, PT; Horn, AS; Houwertjes, MC | 1 |
| Laakso, PS; Sellin, LC | 1 |
| Johnston, D; Lebeda, FJ; Rutecki, PA | 1 |
| Chaudhry, I; Duncalf, D; Foldes, FF; Goldiner, PL; Harsing, LG; Lalezari, I; Nagashima, H; Sugimori, T; Vizi, ES | 1 |
| Fang, XM; Shi, YL; Wang, WP; Zhang, YP | 1 |
| Rasminsky, M; Ricot, PJ | 1 |
| Markus, H; Pomeranz, B | 1 |
| Uchida, Y | 1 |
| Sonoki, H; Sugimoto, T; Tomaru, T; Uchida, Y | 1 |
| Sripada, PK | 1 |
| Barnes, KW; Dorsey, JG; Sentell, KB | 1 |
| Haydon, DA; Requena, J; Simon, AJ | 1 |
| Agoston, S; Biessels, PT; Horn, AS; Houwertjes, MC; Scaf, AH | 1 |
| Scholfield, CN | 1 |
| Mustafa, SJ; Nakazawa, M | 1 |
| Sapru, H; Sundaram, K | 1 |
| Agoston, S; Biessels, PT; Horn, AS | 1 |
| Delbono, O; Kotsias, BA | 1 |
| Price, JI; Siegel, LS | 1 |
| Hotta, K; Oba, T | 1 |
| Lemeignan, M; Molgó, J; Thesleff, S | 1 |
| Chang, CC; Chiou, LC; Hong, SJ; Jou, MJ | 1 |
| Nakamura, F; Sonoki, H; Sugimoto, T; Sumino, S; Tomaru, T; Uchida, Y | 1 |
| Johnson-Winegar, AD; Sellin, LC; Siegel, LS | 1 |
| Freyss-Béguin, M; Griffaton, G; Lechat, P; Millanvoye-Van Brussel, E | 1 |
| Ngo, TT | 1 |
| Finger, W; Martin, C | 1 |
| Uchida, Y; Yoshinaka, Y | 1 |
| Giese, RW; Joppich, M; Joppich-Kuhn, R; Sentissi, A | 1 |
| Greenwood, AG | 1 |
| Gibson, GE; Nicholls, DG; Peterson, C | 2 |
| Atwood, HL; Wojtowicz, JM | 1 |
| Byerly, L; Meech, R; Moody, W | 1 |
| Cahalan, MD; Chandy, KG; DeCoursey, TE; Gupta, S; McLaughlin, C | 1 |
| Gundersen, CB; Miledi, R; Parker, I | 1 |
| Deitmer, JW | 1 |
| Salmenperä, M; Tammisto, T; Wirtavuori, K | 1 |
| Saxon, ME | 1 |
| Alkadhi, KA; Brown, TR; Sabouni, MH | 1 |
| Galvan, M; Sedlmeir, C | 1 |
| Chang, CC; Hong, SJ; Lin, HL; Shieh, BH; Su, MJ | 1 |
| Gorman, AL; Hermann, A | 1 |
| Sellin, LC | 1 |
| Alkadhi, KA; Henderson, EG; Patterson, BA; Quenzer, LF; Volle, RL | 1 |
| Strumwasser, F; Van Harreveld, A | 1 |
| Kryzhanovskiĭ, GN; Polgar, AA; Smirnova, VS; Zinkevich, VA | 1 |
| Enomoto, KI; Maeno, T; Sawada, M | 1 |
| Parnas, H; Segel, LA | 1 |
| Booth, NH; Clark, JD; Crawford, LM; Hatch, RC; Kitzman, JV; Wallner, B | 1 |
| Booth, NH; Crawford, LM; Hatch, RC | 1 |
| Patterson, BA; Quenzer, LF; Volle, RL | 1 |
| Haydon, PG; Holden, AV; Winlow, W | 1 |
| Guerrero, S; Lemeignan, M; Molgó, J | 1 |
| Sitges, M; Tapia, R | 1 |
| Booth, NH; Hatch, RC; Kitzman, JV; Wallner, B | 1 |
| Booth, NH; Brown, J; Clark, JD; Hatch, RC; Kitzman, JV; Wallner, BM | 1 |
| Booth, NH; Clark, JD; Hatch, RC; Kitzman, JV; Wallner, BM | 1 |
| Gibson, GE; Pelmas, CJ; Peterson, C | 1 |
| Anderson, PA; Schwab, WE | 1 |
| Thomsen, RH; Wilson, DF | 1 |
| Gold, MR; Martin, AR | 1 |
| Cozanitis, DA; Jones, CT | 1 |
| Dasgupta, BR; Sellin, LC; Thesleff, S | 1 |
| Lahiri, S; Pokorski, M | 1 |
| Xu, JH; Yang, BZ; Zhou, HJ | 1 |
| Dun, NJ; Simmons, MA | 1 |
| Patterson, BA; Volle, RL | 2 |
| Houston, T; Pleuvry, BJ | 1 |
| Agoston, S; Langrehr, D; Sia, R | 1 |
| Ohkawa, H | 1 |
| Sowoidnich, T; Zetler, G | 1 |
| Apatoff, B; Riker, WK | 1 |
| Higuchi, M; Rokutanda, M; Sakanashi, M; Takeo, S | 1 |
| Fehling, C; Lundh, H | 1 |
| Barker, J; Dufy, B | 1 |
| Ito, Y; Korenaga, S; Tajima, K | 1 |
| Kanaya, S; Katzung, BG | 1 |
| Lynch, C; Shabanowitz, J; Sinn, JA; Spyker, DA | 1 |
| Illes, P; Kromer, W; Scheiblhuber, E | 1 |
| Chang, CC; Su, MJ | 1 |
| Ahnert-Hilger, G; Habermann, E | 1 |
| Mulder, AH; Schoffelmeer, AN; Wemer, J | 1 |
| Kocsis, JD; Waxman, SG | 1 |
| Lymangrover, JR; Matthews, EK; Saffran, M | 1 |
| Saith, S; Schofield, JG | 1 |
| Jack, JJ; Redman, SJ; Wong, K | 1 |
| Jankowska, E; Lundberg, A; Rudomin, P; Sykova, E | 1 |
| Mulder, AH; Schoffelmeer, AN | 2 |
| Arispe, N; Quinta-Ferreira, ME; Rojas, E | 1 |
| Kam, P; Soni, N | 1 |
| Gibson, GE; Peterson, C | 4 |
| Corthay, J; Dunant, Y; Loctin, F | 1 |
| Buckle, PJ; Haas, HL | 1 |
| Riggs, JE | 1 |
| Kennedy, H; Martin, KA; Whitteridge, D | 1 |
| Thompson, S | 1 |
| Crain, B; Crain, SM; Hiller, JM; Peterson, ER; Simon, EJ | 1 |
| Molgó, J; Thesleff, S | 1 |
| Durant, NN; Katz, RL; Lee, C; Nguyen, N | 1 |
| Boev, K; Bonev, A; Gachilova, S; Papasova, M; Zafirov, D | 1 |
| Riker, WK; Sasaki, K | 1 |
| Kurihara, K; Miyake, M | 1 |
| Aleman, V; de Muñoz, DM | 1 |
| Stolc, S; Vlcková, E | 1 |
| Belichenko, VM; Freydin, AA; Lazarev, AV; Safronova, VG; Saxon, ME | 1 |
| Kecskeméti, V; Kelemen, K; Knoll, J; Marko, R | 1 |
| Khan, RA; Lemeignan, M | 1 |
| Alkon, DL; Neary, JT | 1 |
| Kirsch, GE; Narahashi, T | 1 |
| Chiarandini, DJ; Stefani, E | 1 |
| Sánchez, JA; Stefani, E | 1 |
| Kocsis, JD; Ruiz, JA; Waxman, SG | 1 |
| Matsumoto, M; Riker, WK | 1 |
| Wakade, AR; Wakade, TD | 1 |
| Gestrelius, S; Grampp, W | 1 |
| Andersson, O; Grillner, S | 1 |
| Edman, A; Gestrelius, S; Grampp, W | 1 |
| Devor, M | 1 |
| Pongrácz, F; Szente, M | 1 |
| Jørgensen, F | 1 |
| Akoev, GN; Krylov, BV; Vislobokoe, AI | 1 |
| Daniel, EE; Garfield, RE; Jager, LP; Kannan, MS | 1 |
| Apatoff, BR; Riker, WK; Sasaki, K | 1 |
| Cohen, R; Gainer, H; Gallant, PE; Neary, JT; Pant, HC | 1 |
| Franz, P; Galvan, M; Vogel-Wiens, C | 1 |
| Cunnane, TC; Stjärne, L | 1 |
| Bunyevácz, Z; Hadházy, P; Magyar, K; Nguyen, TT; Török, TL; Vizi, ES | 1 |
| Erdélyi, L; Such, G | 1 |
| Csicsaky, M; Krämer, U; Wiegand, H | 1 |
| de Haën, C; Hansen, RS; Johnson, DG; Nist, BJ; Thompson, WJ | 1 |
| Agoston, S; DeWit, DJ; Havinga, H; Pasma, J; Van Dam, GB; Wesseling, H | 1 |
| Bevan, DR; Bevan, JC; Donati, F | 1 |
| Tachibana, M | 1 |
| Coraboeuf, E; Coulombe, A; Malécot, C | 1 |
| Agoston, S; Langrehr, D; Schmutzler, S; Uges, D | 1 |
| Giachetti, D; Mantovani, P; Taddei, E | 1 |
| Driska, SP; Stein, PG | 1 |
| Lamiable, D; Lemeignan, M; Millart, H; Vistelle, R | 1 |
| Douglas, WW; Taraskevich, PS; Tomiko, SA | 1 |
| Laskey, W; Polosa, C; Schondorf, R | 1 |
| Van Harreveld, A | 1 |
| Fehér, O; Gyuris, T; Szente, M | 1 |
| Brailowsky, S; Knight, RT | 1 |
| Booth, NH; Brown, J; Hatch, RC; Kitzman, JV; Wilson, RC; Zahner, JM | 1 |
| Booth, NH; Clark, JD; Hatch, RC; Kitzman, JV; Zahner, JM | 1 |
| Booth, NH; Bush, PB; Hendricks, HL; Kitzman, JV; Wilson, RC; Zahner, JM | 1 |
| Booth, NH; Hatch, RC; Zahner, JM | 1 |
| Agoston, S; Houwertjes, MC; Ket, JM; Maestrone, E; Uges, DR; van Hezik, EJ | 1 |
| Albericio, F; Barany, G | 1 |
| McMurtry, IF | 1 |
| Ekelund, MC | 1 |
| Ninomiya, JG; Suzuki, H | 1 |
| Davis, HP; Gibson, GE; Idowu, A | 1 |
| Gainullin, RZ; Kukushkin, NI; Sosunov, EA | 1 |
| Booth, NH; Brown, J; Cronin, MF; Hatch, RC | 1 |
| Dzoljic, MR; Rupreht, J | 1 |
| Barker, JL; Rogawski, MA | 1 |
| Elfvin, LG; Forsman, CA | 1 |
| Agoston, S; Biessels, P; Den Hertog, A; Pielkenrood, J | 1 |
| Booth, NH; Clark, JD; Hatch, RC; Kitzman, JV | 1 |
| de Langen, CD; Houwertjes, MC; Kingma, JH; Wesseling, H | 1 |
| Aoki, T; Fukushima, K; Ishikawa, J | 1 |
| Boros, M; Chaudhry, IA; Duncalf, RM; Foldes, FF; Nagashima, H; Sherman, EH | 1 |
| Mitchell, MR; Powell, T; Terrar, DA; Twist, VW | 1 |
| Downing, OA; Louttit, JB; Wilson, KA | 1 |
| Illes, P; Meier, C; Starke, K | 1 |
| Agoston, D; Mihály, A | 1 |
| Booth, NH; Bush, PB; Hendricks, HL; Kitzman, JV | 1 |
| Davis, KL; Deutsch, SI; Oldendorf, WH | 1 |
| Booth, NH; Hatch, RC; Kitzman, JV; Wilson, RC | 1 |
| Arzate, ME; Pasantes-Morales, H; Ponce, H | 1 |
| Buirs, B; Sangster, B; Uges, DR | 1 |
| Lamiable, D; Lechat, P; Lemeignan, M; Millart, H; Molgo, J | 1 |
| Miledi, R; Parker, I; Zhu, PH | 1 |
| Birdsall, B; Burgen, AS; Roberts, GC | 1 |
| Gundersen, CB; Jenden, DJ | 1 |
| Atchison, WD; Lalley, PM; Mellon, WS; Peterson, RE | 1 |
| Kocsis, JD; Preston, RJ; Waxman, SG | 1 |
| Haas, HL; Wieser, HG; Yaşargil, MG | 1 |
| Galvan, M | 1 |
| Carlsson, C; Nilsson, E; Rosén, I | 1 |
| Lamiable, D; Millart, H | 1 |
| Castagnoli, N; Fisher, DM; Miller, RD; Rupp, SM; Shinohara, Y | 1 |
| Connors, KA; Eboka, CJ | 2 |
| Collier, B; Lamarca, MV | 1 |
| Fujiwara, S; Kuriyama, H | 1 |
| Agoston, D; Hargittai, P; Nagy, A | 1 |
| Imaizumi, Y; Watanabe, M | 1 |
| Borowitz, JL; Malavé, A; Yim, GK | 1 |
| Dolezal, V; Tucek, S | 1 |
| Abrams, J; Haddad, JG; Walgate, J | 1 |
| Broccoli, AV; Huang, C; Mason, JT | 1 |
| Durant, NN; Henderson, EG; Lambert, JJ; Reynolds, LS; Volle, RL | 1 |
| Durant, NN; Marshall, IG | 1 |
| Madden, KS; van der Kloot, W | 1 |
| Anraku, M; Hashimura, S | 1 |
| Kontani, H; Koshiura, R | 1 |
| Bostock, H; Sears, TA | 1 |
| Ahrén, B; Leander, S; Lundquist, I | 1 |
| Martinez-Aguirre, E | 2 |
| Banna, NR; Jabbur, SJ; Khoury, A; Saadé, NE; Wall, PD | 1 |
| Martínez-Aguirre, E; Wikinski, JA | 1 |
| Fain, GL; Lisman, JE; O'Day, PM | 1 |
| Bagust, J; Forsythe, ID; Kerkut, GA; Loots, JM | 1 |
| Carmeliet, E; Coraboeuf, E | 1 |
| Agoston, S; Greijdanus, B; Scaf, AH; Sohn, YJ; Uges, DR | 1 |
| Ket, JM; Uges, DR; Versluis, A; Wesseling, H | 1 |
| Gibbons, WR; Lipsius, SL | 1 |
| Casamenti, F; Corradetti, R; Löffelholz, K; Mantovani, P; Pepeu, G | 1 |
| Galvan, M; Grafe, P; ten Bruggencate, G | 2 |
| Castagnoli, N; Miller, RD; Shinohara, Y | 1 |
| Crain, B; Crain, SM; Peterson, ER | 1 |
| Goto, A; Watanabe, M | 1 |
| Snyders, DJ; Van Bogaert, PP | 1 |
| Al-Timari, A; D'Silva, C; Douglas, KT | 1 |
| Huidobro-Toro, JP; Rezvani, A; Way, EL | 1 |
| Fontana, MD; Pavani, NJ; Vital Brazil, O | 1 |
| Mugelli, A | 1 |
| Daniel, EE; Davis, C; Jones, TR; Kannan, MS | 1 |
| Boonstra, S; Haenen, HT; Sia, RL; Wesseling, H; Westra, P | 1 |
| Sobek, V | 1 |
| Faber, DS; Kaars, C | 1 |
| Glover, WE | 1 |
| Gallin, EK; Livengood, DR | 1 |
| Bowman, WC; Marshall, RJ; Rodger, IW; Savage, AO | 1 |
| Agoston, S; de Lange, AR; Erdmann, W; Evenhuis, J; Salt, PJ; Wouthuyzen, W | 1 |
| Stone, TW | 1 |
| Bello, A; Garcia, A; Izquierdo, J; Martínez-Aguirre, E; Velarde, H; Wikinski, JA | 1 |
| Shimahara, T | 1 |
| Huizinga, T; Uges, DR | 1 |
| Zangger, P | 1 |
| Watson, E | 1 |
| Sia, RL; Zandstra, DF | 1 |
| Nicholson, SS; Prejean, CJ | 1 |
| Bostock, H; Sears, TA; Sherratt, RM | 1 |
| Frank, R; Sirons, GJ; Wilson, D | 1 |
| Burley, ES; Jacobs, RS | 1 |
| Garcia, AG; Kirpekar, SM; Prat, JC | 1 |
| Fujiwara, M; Ikushima, S; Muramatsu, I | 1 |
| Arzate, ME; Pasantes-Morales, H | 1 |
| Aceves, J; Cuello, AC | 1 |
| Moritoki, H; Su, C | 1 |
| Coraboeuf, E; Deroubaix, E; Le Floch, M; Sebeszta, M | 1 |
| Terakawa, S | 1 |
| James, TN; Urthaler, F; Woods, WT | 1 |
| Hove, K; Sand, O | 1 |
| Khan, AR; Wohlfart, B; Wollmer, P | 1 |
| Boyett, MR | 1 |
| Hopkins, J; Klein, L | 1 |
| Plant, TD; Standen, NB | 1 |
| Merrifield, RB; Tam, JP; Wang, BS; Wang, SS | 1 |
| Hara, Y; Kitamura, K; Kuriyama, H | 1 |
| Booij, LH; Crul, JF; Muytjens, HL; van der Ploeg, GC | 1 |
| Cooper, GM; Hall, GM; Lister, D; Lucke, JN | 1 |
| Perkins, MN; Stone, TW | 1 |
| Boldt, W; Nilius, B | 1 |
| Au, E; Durant, NN; Katz, RL; Lee, C | 1 |
| Czech, K; Gogolák, G; Stumpf, C | 1 |
| Bouma, P; Uges, DR | 1 |
| Furukawa, T; Hiraoka, M; Yamane, T | 1 |
| Bijak, M; Jarolimek, W; Misgeld, U | 1 |
| Garratt, JC; Owen, DG; Robertson, B; Stephens, GJ | 1 |
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| Andreani, A; Leoni, A; Locatelli, A; Morigi, R; Pietra, C; Rambaldi, M; Villetti, G | 1 |
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| Angove, MJ; Ikhsan, J; Johnson, BB; Wells, JD | 1 |
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| Ando, M; Ito, S; Kameda, M; Kawamoto, H; Kobayashi, K; Nakama, C; Ozaki, S; Sato, N; Suzuki, T; Tani, T; Tokita, S | 1 |
| Kalaichelvan, S; Karpagam, J; Sebastian, S; Sundaraganesan, N | 1 |
| Aubert, C; Evanno, Y; Gandon, V; Garcia, P; George, P; Malacria, M; Ricci, G; Sevrin, M | 1 |
| Kolczyńska, K; Raczyńska, ED; Stępniewski, TM | 1 |
| King, AE; Visockis, V | 1 |
| Balazs, M; Barrett, K; Berezhkovsky, L; Blair, W; Chang, C; Delarosa, D; DeVoss, J; Driscoll, J; Eigenbrot, C; Ghilardi, N; Gibbons, P; Halladay, J; Johnson, A; Kohli, PB; Lai, Y; Liang, J; Liu, Y; Lyssikatos, J; Magnuson, S; Mantik, P; Menghrajani, K; Murray, J; Peng, I; Sambrone, A; Shia, S; Shin, Y; Smith, J; Sohn, S; Tsui, V; Ultsch, M; van Abbema, A; Wu, LC; Xiao, Y; Yang, W; Young, J; Zhang, B; Zhu, BY | 1 |
| Belaj, F; Dojer, B; Kristl, M; Pevec, A | 1 |
| Page, JC; Shi, R; Yan, R | 1 |
| Ejaz, SA; Hassan, S; Iqbal, J; Lecka, J; Saeed, A; Sévigny, J; Shabir, G; Shehzad, M; Ullah Khan, S | 1 |
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| Cortese, F; De Giglio, L; Pennisi, EM | 1 |
12 review(s) available for alpha-aminopyridine and 4-aminopyridine
| Article | Year |
|---|---|
Effects of drugs on neurotransmitter release: experiments in vivo and in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cell Membrane Permeability; Edetic Acid; Egtazic Acid; gamma-Aminobutyric Acid; Lanthanum; Mice; Motor Activity; Neurotransmitter Agents; Ruthenium Red; Sodium; Substantia Nigra; Synapses; Synaptosomes; Veratridine | 1985 |
[Presynaptic effects of aminopyridines on the neuromuscular junction of vertebrates].
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Aminoquinolines; Animals; Anura; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Potassium; Pyridines; Synaptic Transmission; Vertebrates | 1985 |
[Research progress on a new potassium channel-blocking agent--4-aminopyridine].
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Humans; Ion Channels; Myasthenia Gravis; Potassium | 1986 |
Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Charybdotoxin; Hippocampus; In Vitro Techniques; Ion Channels; Neurons; Norepinephrine; Potassium; Rats; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1987 |
Pharmacology of dementia.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aged; Aminopyridines; Central Nervous System Stimulants; Cerebrovascular Circulation; Clinical Trials as Topic; Dementia; Double-Blind Method; Humans; Levodopa; Nafronyl; Narcotic Antagonists; Nerve Tissue Proteins; Parasympathomimetics; Pentylenetetrazole; Physostigmine; Piracetam; Procainamide; Vasodilator Agents; Vasopressins | 1986 |
Cholinergic approaches to the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Alanine; Alzheimer Disease; Aminopyridines; Arecoline; Clinical Trials as Topic; Humans; Parasympathomimetics; Physostigmine; Piracetam; Pyrrolidines; Research Design; Succinimides; Synapses | 1986 |
On the mechanism of acetylcholine release.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Anura; Aplysia; Electric Organ; Freeze Fracturing; Freezing; Guinea Pigs; In Vitro Techniques; Liposomes; Microscopy, Electron; Neuromuscular Junction; Rats; Synapses; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles; Synaptosomes; Torpedo | 1986 |
The action of batulinum toxin at the neuromuscular junction.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Botulinum Toxins; Botulism; Calcium; Clostridium botulinum; Humans; Neuromuscular Junction; Neurotransmitter Agents; Synaptic Transmission | 1981 |
Ataranalgesia. A review.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepines; Drug Combinations; Heart; Humans; Ketamine; Neuromuscular Junction | 1984 |
4-aminopyridine-a review.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Botulism; Central Nervous System; Humans; Ion Channels; Myasthenia Gravis; Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Neuromuscular Diseases; Neuromuscular Junction; Structure-Activity Relationship | 1982 |
Pharmacologic enhancement of neuromuscular transmission in myasthenia gravis.
Topics: 4-Aminopyridine; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Ambenonium Chloride; Aminopyridines; Calcium; Cholinesterase Inhibitors; Cyclic AMP; Edrophonium; Ephedrine; Germine Acetates; Guanidine; Guanidines; Humans; Myasthenia Gravis; Neostigmine; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Potassium; Pyridostigmine Bromide; Synapses; Synaptic Transmission | 1982 |
Neuromuscular blocking drugs in anaesthesia.
Topics: 4-Aminopyridine; Acid-Base Equilibrium; Adult; Age Factors; Aminopyridines; Atropine; Child; Cholinesterase Inhibitors; Electromyography; Glycopyrrolate; Humans; Muscle Contraction; Neuromuscular Blocking Agents; Neuromuscular Junction; Succinylcholine; Water-Electrolyte Balance | 1984 |
5 trial(s) available for alpha-aminopyridine and 4-aminopyridine
| Article | Year |
|---|---|
4-Aminopyridine in the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Aged; Aged, 80 and over; Alzheimer Disease; Aminopyridines; Brain; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Receptors, Cholinergic | 1988 |
Pharmacology of dementia.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aged; Aminopyridines; Central Nervous System Stimulants; Cerebrovascular Circulation; Clinical Trials as Topic; Dementia; Double-Blind Method; Humans; Levodopa; Nafronyl; Narcotic Antagonists; Nerve Tissue Proteins; Parasympathomimetics; Pentylenetetrazole; Physostigmine; Piracetam; Procainamide; Vasodilator Agents; Vasopressins | 1986 |
Cholinergic approaches to the treatment of Alzheimer's disease.
Topics: 4-Aminopyridine; Alanine; Alzheimer Disease; Aminopyridines; Arecoline; Clinical Trials as Topic; Humans; Parasympathomimetics; Physostigmine; Piracetam; Pyrrolidines; Research Design; Succinimides; Synapses | 1986 |
Comparison of midazolam (Ro 21-3981) and diazepam as complement of ketamine-air anesthesia in children.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, General; Atropine; Benzodiazepines; Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Ketamine; Male; Midazolam; Prospective Studies; Random Allocation; Time Factors | 1986 |
Effects of 4-aminopyridine in elderly patients with Alzheimer's disease.
Topics: 4-Aminopyridine; Aged; Alzheimer Disease; Aminopyridines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Random Allocation | 1984 |
651 other study(ies) available for alpha-aminopyridine and 4-aminopyridine
| Article | Year |
|---|---|
2,4-Diamino-5-benzylpyrimidines and analogues as antibacterial agents. 3. C-Benzylation of aminopyridines with phenolic Mannich bases. Synthesis of 1- and 3-deaza analogues of trimethoprim.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Escherichia coli; Folic Acid Antagonists; In Vitro Techniques; Mannich Bases; Phenols; Rats; Structure-Activity Relationship; Trimethoprim | 1980 |
Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity.
Topics: Anti-HIV Agents; Cells, Cultured; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Organophosphonates; Pyrimidine Nucleosides; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2011 |
Effect of tetrahydroaminoacridine and 4-aminopyridine on recovery from ketamine-diazepam anesthesia in the macacus rhesus monkey.
Topics: 4-Aminopyridine; Acridines; Aminopyridines; Anesthesia, Intravenous; Animals; Diazepam; Electroencephalography; Haplorhini; Ketamine; Macaca mulatta; Tacrine | 1979 |
Mechanism of aminopyridine-induced release of [3H]dopamine from rat brain synaptosomes.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Brain; Cadmium; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cobalt; Dopamine; In Vitro Techniques; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synaptosomes | 1991 |
Changes in the ionic currents sensitivity to inhibitors in twitch rat skeletal muscles following denervation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Drug Resistance; Ion Channels; Muscle Denervation; Muscles; Permeability; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1985 |
Potentiation of a transient outward current by Na+ influx in crayfish neurones.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Astacoidea; Egtazic Acid; Ion Channels; Motor Neurons; Ouabain; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Effects of potassium channel-blocking agents on spontaneous discharges from neuromas in rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Conductivity; Gallamine Triethiodide; Ion Channels; Neoplasms; Nerve Fibers, Myelinated; Neuroma; Peripheral Nervous System Diseases; Potassium; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Aminopyridines; Animals; Cell Membrane; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Ion Channels; Kinetics; Myocardium; Nucleotides; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1985 |
Effects of 3,4-diaminopyridine and tetraethylammonium on the pre- and post-junctional alpha-adrenoceptor mediated inhibitory actions of noradrenaline in the guinea-pig ileum.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Atropine; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Norepinephrine; Receptors, Adrenergic, alpha; Tetraethylammonium Compounds | 1985 |
Lymphocyte membrane potential and Ca2+-sensitive potassium channels described by oxonol dye fluorescence measurements.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcimycin; Calcium; Cell Membrane Permeability; Electrodes; Flow Cytometry; Fluorescent Dyes; Humans; Ion Channels; Isoxazoles; Lymphocytes; Mathematics; Membrane Potentials; Mice; Oxazoles; Potassium; Quinine; Trifluoperazine | 1985 |
Effects of K+-channel blockers on transmitter release in bullfrog sympathetic ganglia.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Calcium; Cesium; Drug Synergism; Electric Conductivity; Ganglia, Sympathetic; Ion Channels; Mathematics; Membrane Potentials; Neurotransmitter Agents; Potassium; Rana catesbeiana; Synaptic Transmission; Tetraethylammonium Compounds | 1985 |
Calcium dependence of A-currents in perfused Aplysia neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Calcium; Cobalt; Ganglia; In Vitro Techniques; Ion Channels; Membrane Potentials; Neural Conduction; Potassium | 1985 |
Voltage-dependent potassium currents in developing neurones from quail mesencephalic neural crest.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cells, Cultured; Ion Channels; Mesencephalon; Neural Crest; Neurons; Potassium; Quail; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1985 |
Ligature-induced injury in peripheral nerve: electrophysiological observations on changes in action potential characteristics following blockade of potassium conductance.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Electrophysiology; Ion Channels; Myelin Sheath; Peripheral Nerve Injuries; Peripheral Nerves; Potassium; Rats; Rats, Inbred Strains | 1985 |
Taurine on hippocampal slices: comparison to GABA and glycine, and antagonism by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Chlorides; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurotransmitter Agents; Taurine | 1985 |
[Effect of potassium and calcium channel blockers on changes in the transepithelial potential and spike responses of electroreceptors of the ampullae of Lorenzini in the skate].
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cations, Divalent; Edetic Acid; Electricity; Fishes; Ion Channels; Membrane Potentials; Potassium; Sensory Receptor Cells; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Myelin sheath remodelling in regenerated rat sciatic nerve.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Female; Ion Channels; Male; Myelin Sheath; Nerve Regeneration; Peripheral Nerves; Potassium; Ranvier's Nodes; Rats; Rats, Inbred Strains; Sciatic Nerve | 1985 |
Further studies on the action of baclofen on neurons of the dorsolateral septal nucleus of the rat, in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Baclofen; Cell Membrane; Electric Conductivity; In Vitro Techniques; Ion Channels; Membrane Potentials; Potassium; Rats; Septal Nuclei; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Low-threshold, slow-inactivating Na+ potentials in the cockroach giant axon.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Axons; Calcium; Ion Channels; Male; Membrane Potentials; Periplaneta; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
A transient outward current in isolated cells from the crista terminalis of rabbit heart.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Heart; In Vitro Techniques; Ion Channels; Kinetics; Myocardium; Potassium; Rabbits; Tetrodotoxin | 1985 |
A calcium-activated potassium current in motor nerve terminals of the mouse.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Barium; Calcium; Cobalt; In Vitro Techniques; Ion Channels; Manganese; Mice; Motor Endplate; Neuromuscular Junction; Potassium; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Potassium channels mediate killing by human natural killer cells.
Topics: 4-Aminopyridine; Aminopyridines; Cadmium; Calcium; Cytotoxicity, Immunologic; Electric Conductivity; Humans; Ion Channels; Killer Cells, Natural; Membrane Potentials; Potassium; Quinidine; Verapamil | 1986 |
Electrical activity of mouse motor endings during muscle reinnervation.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Ion Channels; Membrane Potentials; Mice; Motor Neurons; Nerve Regeneration; Potassium; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Bronchodilator activity of a nonxanthine phosphodiesterase inhibitor; 2,4-diamino-5-cyano-6-bromopyridine (compound I).
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-Aminopyridine; Aminopyridines; Animals; Bronchi; Bronchodilator Agents; Carbachol; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Muscle, Smooth; Phosphodiesterase Inhibitors; Rabbits | 1986 |
Two different presynaptic calcium currents in mouse motor nerve terminals.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Barium; Cadmium; Calcium; Diltiazem; In Vitro Techniques; Ion Channels; Kinetics; Manganese; Mice; Motor Neurons; Neuromuscular Junction; Potassium; Strontium; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1986 |
Potassium channel blockade: A mechanism for suppressing ventricular fibrillation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bethanidine; Bretylium Compounds; Cesium; Chickens; Decapodiformes; Dogs; Guanethidine; Ion Channels; Lidocaine; Methylguanidine; Procainamide; Tetraethylammonium Compounds; Ventricular Fibrillation | 1986 |
Ion channels in rabbit cultured fibroblasts.
Topics: 4-Aminopyridine; Aminopyridines; Amphibian Proteins; Animals; Calcium; Carrier Proteins; Cells, Cultured; Chlorides; Fibroblasts; Ion Channels; Membrane Potentials; Potassium; Rabbits; Rats; Rats, Inbred Strains; Saxitoxin; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
Autoreceptor-mediated changes in dopaminergic terminal excitability: effects of potassium channel blockers.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Apomorphine; Corpus Striatum; Electric Stimulation; Ion Channels; Male; Neural Inhibition; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Inhibition of calcium currents in cultured rat dorsal root ganglion neurones by (-)-baclofen.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Baclofen; Cardiovascular Agents; Cells, Cultured; Ganglia, Spinal; Ion Channels; Muscle Relaxation; Neurons; Rats | 1986 |
The action of thallium acetate on phasic transmitter release in the mouse neuromuscular junction.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Evoked Potentials; In Vitro Techniques; Ion Channels; Mice; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Organometallic Compounds; Thallium | 1986 |
Single transient K channels in mammalian sensory neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Ganglia, Spinal; Guinea Pigs; Ion Channels; Kinetics; Membrane Potentials; Neurons, Afferent; Potassium | 1986 |
Potassium channels in Myxicola giant axons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Ion Channels; Neural Conduction; Polychaeta; Potassium | 1986 |
Characteristics of phasic and tonic sympathetic ganglion cells of the guinea-pig.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Barium; Bethanechol; Bethanechol Compounds; Cell Membrane; Female; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Manganese; Neurons; Time Factors | 1986 |
Interaction of 4-aminopyridine with [3H]phencyclidine receptors in rat brain homogenates.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Binding, Competitive; Brain; Ion Channels; Male; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Synaptic Membranes | 1986 |
Non-synaptic modulation of repetitive firing by adenosine is antagonized by 4-aminopyridine in a rat hippocampal slice.
Topics: 4-Aminopyridine; Action Potentials; Adenosine; Aminopyridines; Animals; Calcium; Hippocampus; In Vitro Techniques; Ion Channels; Phenylisopropyladenosine; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Modification of motor nerve terminal excitability by alkanols and volatile anaesthetics.
Topics: 1-Butanol; 1-Octanol; 4-Aminopyridine; Alcohols; Aminopyridines; Anesthesia, Inhalation; Animals; Barium; Butanols; Enflurane; Hexanols; Ion Channels; Mice; Motor Neurons; Octanols; Pentobarbital; Sodium | 1986 |
Mitogen-induced changes in Ca2+ permeability are not mediated by voltage-gated K+ channels.
Topics: 4-Aminopyridine; Aminopyridines; Calcium; Cell Membrane Permeability; Cytosol; Humans; Ion Channels; Kinetics; Membrane Potentials; Mitogens; Phytohemagglutinins; Potassium; Quinine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Potassium channels in human NK cells are involved in discrete stages of the killing process.
Topics: 4-Aminopyridine; Aminopyridines; Cadmium; Calcium; Cytotoxicity, Immunologic; Edetic Acid; Humans; Ion Channels; Killer Cells, Natural; Killer Factors, Yeast; Proteins; Quinidine; Verapamil | 1986 |
Catechol: a potent and specific inhibitor of the fast potassium channel in frog primary afferent neurones.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Catechols; Depression, Chemical; Drug Interactions; In Vitro Techniques; Ion Channels; Neurons, Afferent; Potassium; Rana catesbeiana; Sodium; Time Factors | 1986 |
Neural control of gastro-intestinal motility; events following receptor activation.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aminopyridines; Animals; Calcium; Cecum; Gastrointestinal Motility; Guinea Pigs; Ion Channels; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Potassium; Purines; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Neurotransmitter | 1986 |
Intracellular and extracellular action potentials in frog muscle fibre upon blocking the potassium conductivity.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; In Vitro Techniques; Ion Channels; Muscles; Potassium; Rana ridibunda | 1986 |
Mammalian optic nerve fibers display two pharmacologically distinct potassium channels.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Decapodiformes; In Vitro Techniques; Ion Channels; Kinetics; Optic Nerve; Potassium; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Dendrotoxin: a selective blocker of a non-inactivating potassium current in guinea-pig dorsal root ganglion neurones.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Elapid Venoms; Ganglia, Spinal; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
A Drosophila mutation that eliminates a calcium-dependent potassium current.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Drosophila; Female; Ion Channels; Muscles; Mutation; Potassium | 1986 |
Transient and delayed potassium currents in the Retzius cell of the leech, Macrobdella decora.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electrophysiology; Ion Channels; Leeches; Membrane Potentials; Neurons; Potassium; Tetraethylammonium Compounds | 1986 |
Effects of 4-aminopyridine on the action potential and the after-hyperpolarization of cat spinal motoneurons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cats; Ion Channels; Membrane Potentials; Motor Neurons; Potassium; Spinal Cord | 1986 |
m-Azido-phencyclidine covalently labels the rat brain PCP receptor, a putative K channel.
Topics: 4-Aminopyridine; Affinity Labels; Aminopyridines; Animals; Azides; Brain; Cell Membrane; Ion Channels; Molecular Weight; Phencyclidine; Photochemistry; Potassium; Quaternary Ammonium Compounds; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1986 |
The effects of rubidium ions on components of the potassium conductance in the frog node of Ranvier.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cell Membrane Permeability; In Vitro Techniques; Ion Channels; Kinetics; Potassium; Rana esculenta; Ranvier's Nodes; Rubidium; Time Factors | 1986 |
Currents under voltage clamp of burst-forming neurons of the cardiac ganglion of the lobster (Homarus americanus).
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Calcium; Electric Stimulation; Ganglia; Ion Channels; Membrane Potentials; Nephropidae; Neural Inhibition; Neurons; Potassium; Synaptic Transmission; Tetrodotoxin | 1986 |
Ionic channels in mouse astrocytes in culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Astrocytes; Cells, Cultured; Chlorides; Ion Channels; Membrane Potentials; Mice; Potassium; Scorpion Venoms; Sodium; Tetrodotoxin; Veratridine | 1987 |
Autologous mixed-lymphocyte reaction in man. XVII. In vitro effect of ion channel-blocking agents on the autologous mixed-lymphocyte response.
Topics: 4-Aminopyridine; Aminopyridines; Dose-Response Relationship, Drug; Humans; Interleukin-2; Ion Channels; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Quaternary Ammonium Compounds; Quinine; Receptors, Immunologic; Receptors, Interleukin-2; Recombinant Proteins; T-Lymphocytes; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1987 |
Selective blockade of components of potassium activation in Myxicola axons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Deuterium; Deuterium Oxide; Electric Conductivity; Ion Channels; Kinetics; Polychaeta; Potassium; Water | 1987 |
Phasic contractions of canine and human coronary arteries induced by potassium channel blockers.
Topics: 4-Aminopyridine; Adult; Aged; Amifampridine; Aminopyridines; Angina Pectoris, Variant; Animals; Arteries; Coronary Vasospasm; Coronary Vessels; Dogs; Female; Humans; Ion Channels; Macaca mulatta; Male; Middle Aged; Models, Biological; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Swine; Tetraethylammonium Compounds; Vasoconstriction | 1986 |
4-Aminopyridine improves clinical signs in multiple sclerosis.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Flicker Fusion; Humans; Ion Channels; Male; Middle Aged; Movement Disorders; Multiple Sclerosis; Neural Conduction; Potassium; Sodium; Vision Disorders; Visual Acuity | 1987 |
A possible role for K+ channels in tumor cell injury. Membrane vesicle shedding and nuclear DNA fragmentation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Line; Cell Membrane; Cell Nucleus; DNA, Neoplasm; Ion Channels; Mast-Cell Sarcoma; Mice; Microscopy, Electron, Scanning; Potassium; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Effects of tonicity on the pacemaker activity of guinea-pig sino-atrial node.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Atropine; Calcium; Cesium; Chlorides; Female; Guinea Pigs; Heart Rate; Ion Channels; Magnesium; Male; Membrane Potentials; Phentolamine; Potassium; Propranolol; Sinoatrial Node; Sodium; Sucrose; Tetraethylammonium Compounds; Tetrodotoxin | 1986 |
Potassium channel blockers and impulse propagation in murine motor endplate disease.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; In Vitro Techniques; Ion Channels; Mice; Mice, Inbred C3H; Motor Endplate; Neuromuscular Diseases; Neuromuscular Junction; Potassium; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Mechanism of increased amplitude and duration of the plateau with sudden shortening of diastolic intervals in rabbit ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Caffeine; Electric Conductivity; Guinea Pigs; Heart Rate; Heart Ventricles; In Vitro Techniques; Ion Channels; Membrane Potentials; Myocardial Contraction; Rabbits; Time Factors; Ventricular Function | 1987 |
Differential sensitivity of amphibian nodal and paranodal K+ channels to 4-aminopyridine and TEA.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Electric Conductivity; Ion Channels; Nerve Fibers; Potassium; Rana pipiens; Ranvier's Nodes; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellum.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cell Differentiation; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Histocytochemistry; Immunoenzyme Techniques; Ion Channels; Microscopy, Phase-Contrast; Potassium; Purkinje Cells; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Immunocytochemical and electrophysiological differentiation of rat cerebellar granule cells in explant cultures.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Differentiation; Cells, Cultured; Cerebellum; Electric Conductivity; Glial Fibrillary Acidic Protein; Immunoenzyme Techniques; Ion Channels; Membrane Potentials; Phosphopyruvate Hydratase; Potassium; Rats; Rats, Inbred Strains; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1987 |
Ionic mechanism of the outward current induced by intracellular injection of inositol trisphosphate into Aplysia neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Calcium; Chlorides; Egtazic Acid; Electric Conductivity; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Membrane Potentials; Neurons; Potassium; Sugar Phosphates; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Functional differences between 4-aminopyridine and tetraethylammonium-sensitive potassium channels in myelinated axons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Ion Channels; Nerve Fibers, Myelinated; Potassium; Rats; Rats, Inbred Strains; Sciatic Nerve; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Actions of convulsants, 4-aminopyridine and pentylenetetrazole, on the transient outward current of single isolated nodose ganglion neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Convulsants; Ion Channels; Nodose Ganglion; Pentylenetetrazole; Rabbits; Vagus Nerve | 1987 |
Characterization of the basolateral membrane conductance of Necturus urinary bladder.
Topics: 4-Aminopyridine; Amifampridine; Amiloride; Aminopyridines; Animals; Cell Membrane; Chlorides; Decamethonium Compounds; Electric Conductivity; Epithelium; Ion Channels; Male; Membrane Potentials; Necturus; Potassium; Seasons; Tetraethylammonium Compounds; Urinary Bladder; Water-Electrolyte Balance | 1987 |
4-aminopyridine activates a cholinergic chloride conductance in isolated Helix neurons.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Chlorides; Drug Interactions; Ganglia; Helix, Snails; In Vitro Techniques; Ion Channels; Receptors, Cholinergic; Snails | 1987 |
Pharmacological control of 86Rb efflux from mouse pancreatic islets.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Female; In Vitro Techniques; Insulin; Insulin Secretion; Ion Channels; Islets of Langerhans; Kinetics; Mice; Mice, Inbred Strains; Quinine; Radioisotopes; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
In vitro characterization of neurons in the ventral part of the nucleus tractus solitarius. II. Ionic basis for repetitive firing patterns.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Egtazic Acid; Guinea Pigs; In Vitro Techniques; Ion Channels; Medulla Oblongata; Potassium; Respiratory Center | 1987 |
Inactivation of calcium channel current in rat uterine smooth muscle: evidence for calcium- and voltage-mediated mechanisms.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Barium; Calcium; Extracellular Space; Female; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth; Rats; Strontium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Uterus | 1986 |
Repetitive inhibitory postsynaptic potentials evoked by 4-aminopyridine in hippocampal neurons in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Aminopyridines; Animals; Calcium; Fenclonine; Hippocampus; In Vitro Techniques; Interneurons; Isoproterenol; Male; Membrane Potentials; Neural Inhibition; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1987 |
Potassium channel blockade induces rhythmic activity in a conditional burster neuron.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Apamin; Calcium; Digestive System; Ion Channels; Nephropidae; Neurons; Potassium; Tetraethylammonium Compounds | 1987 |
Physiological properties of regenerated rat sciatic nerve following lesions at different postnatal ages.
Topics: 4-Aminopyridine; Aging; Aminopyridines; Animals; Ion Channels; Myelin Sheath; Nerve Regeneration; Peripheral Nerve Injuries; Peripheral Nerves; Potassium; Rats; Rats, Inbred Strains; Sciatic Nerve | 1987 |
Excitation-secretion coupling: ionic currents in glomerulosa cells: effects of adrenocorticotropin and K+ channel blockers.
Topics: 4-Aminopyridine; Adrenal Glands; Adrenocorticotropic Hormone; Aminopyridines; Animals; Calcium; Cations; Cobalt; Electric Conductivity; Ion Channels; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
[Effects of vasodilators on cyclic contraction induced by 3,4-diaminopyridine in isolated porcine coronary arteries].
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Angina Pectoris; Animals; Calcium; Coronary Vessels; Drug Interactions; Guanidines; In Vitro Techniques; Ion Channels; Periodicity; Pinacidil; Potassium; Swine; Vasodilator Agents | 1987 |
Modulation of potassium conductances by an endogenous neuropeptide in neurones of Aplysia californica.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Aplysia; Calcium; Cyclic AMP; FMRFamide; In Vitro Techniques; Ion Channels; Neurons; Neuropeptides; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1987 |
Ca2+-movements in muscle modulated by the state of K+-channels in the sarcoplasmic reticulum membranes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bufo marinus; Calcium; In Vitro Techniques; Ion Channels; Muscles; Potassium; Sarcoplasmic Reticulum; Sodium | 1987 |
Calcium and ATP regulate the activity of a non-selective cation channel in a rat insulinoma cell line.
Topics: 4-Aminopyridine; Adenoma, Islet Cell; Adenosine Triphosphate; Aminopyridines; Animals; Calcium; Cations; Cell Line; Insulinoma; Ion Channels; Kinetics; Membrane Potentials; Quinine; Rats | 1987 |
Bay k 8644, a calcium entry promoter, as an antidote in verapamil intoxication in rabbits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Antidotes; Atrioventricular Node; Blood Pressure; Cardiovascular Agents; Electrocardiography; Female; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Male; Pyridines; Rabbits; Verapamil | 1987 |
4-Aminopyridine inhibits synaptosomal plasma membrane protein phosphorylation in vitro: effect of the selective NMDA-antagonist 2-amino-5-phosphonovalerate.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Hippocampus; In Vitro Techniques; Ion Channels; Male; Membrane Proteins; Molecular Weight; Nerve Tissue Proteins; Phosphoproteins; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Valine | 1987 |
Effect of channel blockers on potassium efflux from metabolically exhausted frog skeletal muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Apamin; Barium; Cell Membrane Permeability; Decamethonium Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Glyburide; In Vitro Techniques; Ion Channels; Muscles; Potassium; Quinine; Rana temporaria; Rubidium; Scorpion Venoms; Tetraethylammonium Compounds; Tolbutamide | 1987 |
Function and distribution of three types of rectifying channel in rat spinal root myelinated axons.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Aminopyridines; Animals; Axons; Barium; Cesium; Female; Ion Channels; Membrane Potentials; Potassium; Rats; Rats, Inbred Strains; Spinal Nerve Roots; Tetraethylammonium Compounds; Tetrodotoxin | 1987 |
Transient outward currents and changes of their gating properties after cell activation in thrombocytes of the newt.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Blood Platelets; In Vitro Techniques; Ion Channels; Membrane Potentials; Potassium; Triturus | 1987 |
Two distinct calcium-activated potassium currents in a rat anterior pituitary cell line.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Apamin; Calcium; Cell Line; Depression, Chemical; Edetic Acid; Ion Channels; Pituitary Gland, Anterior; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Effects of stimulus frequency and potassium channel blockade on the secretion of vasopressin and oxytocin from the neurohypophysis.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Electric Stimulation; In Vitro Techniques; Ion Channels; Male; Oxytocin; Pituitary Gland, Posterior; Potassium; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Vasopressins | 1987 |
The inhibitory effects of K+ channel-blocking agents on T lymphocyte proliferation and lymphokine production are "nonspecific".
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Line; Cytotoxicity, Immunologic; Depression, Chemical; Ion Channels; Lymphocyte Activation; Lymphokines; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mitogens; Potassium; T-Lymphocytes; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Pharmacological characterization of the serotonin-sensitive potassium channel of Aplysia sensory neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Barium; Cobalt; Electrophysiology; Ion Channels; Neurons, Afferent; Potassium; Serotonin; Tetraethylammonium Compounds | 1987 |
Sodium currents in axon-associated Schwann cells from adult rabbits.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; In Vitro Techniques; Ion Channels; Microscopy, Electron; Nerve Fibers; Rabbits; Schwann Cells; Sciatic Nerve; Sodium; Tetrodotoxin; Time Factors | 1987 |
The actions of presynaptic snake toxins on membrane currents of mouse motor nerve terminals.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Apamin; Aprotinin; Calcium; In Vitro Techniques; Ion Channels; Mice; Motor Endplate; Neuromuscular Junction; Phospholipases A; Phospholipases A2; Potassium; Snake Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Phencyclidine blocks two potassium currents in spinal neurons in cell culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Embryo, Mammalian; Ion Channels; Mice; Mice, Inbred C57BL; Neurons; Phencyclidine; Potassium; Spinal Cord; Tetraethylammonium Compounds | 1987 |
The effects of nicorandil on phasic contractions of isolated canine coronary artery.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calmodulin; Coronary Vessels; Dogs; Ergonovine; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Vasodilator Agents | 1987 |
Membrane currents that govern smooth muscle contraction in a ctenophore.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cell Membrane; Cnidaria; Cobalt; Electric Conductivity; Ion Channels; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
The effects of tetraethylammonium ions, 4-aminopyridine or quinidine on K+-currents in single smooth muscle cells of the rabbit portal vein.
Topics: 4-Aminopyridine; Aminopyridines; Animals; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth, Vascular; Potassium; Quinidine; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Voltage-dependent K+ currents and underlying single K+ channels in pheochromocytoma cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Charybdotoxin; Ion Channels; Membrane Potentials; Pheochromocytoma; Potassium; Quinidine; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1988 |
Outward currents of single hippocampal cells obtained from the adult guinea-pig.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cell Separation; Central Nervous System Stimulants; Cobalt; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Kinetics; Male; Neurons; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1987 |
The effect of known K+-channel blockers on the electrical activity of bovine lymphatic smooth muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Barium; Cattle; Cesium; Ion Channels; Kinetics; Lymphatic System; Membrane Potentials; Muscle, Smooth; Potassium; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
[Role of the Ca and K currents on the afferent synaptic transmission of the isolated labyrinth of the frog].
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Ear, Inner; Evoked Potentials; Hair Cells, Auditory; In Vitro Techniques; Ion Channels; Potassium; Ranidae; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Presynaptic K-channel blockade counteracts the depressant effect of adenosine in olfactory cortex.
Topics: 4-Aminopyridine; Adenosine; Amifampridine; Aminopyridines; Animals; Cerebral Cortex; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Male; Olfactory Bulb; Olfactory Pathways; Potassium; Synapses | 1988 |
A whole-cell and single-channel study of the voltage-dependent outward potassium current in avian hepatocytes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cells, Cultured; Chickens; Electric Conductivity; Electrophysiology; Ion Channels; Kinetics; Liver; Male; Membrane Potentials; Potassium; Tetrodotoxin | 1988 |
Changes in nerve membrane polarization following repeated exposure to soman.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane Permeability; Ion Channels; Male; Membrane Potentials; Neural Conduction; Neurons; Ouabain; Potassium; Rats; Rats, Inbred Strains; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Soman | 1988 |
Evidence for the presence of two types of potassium channels in the rat optic nerve.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Female; Ion Channels; Nerve Fibers; Optic Nerve; Potassium; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Ammonium Chloride; Animals; Botulinum Toxins; Calcium; Cholera Toxin; Colforsin; Female; Guanidine; Guanidines; In Vitro Techniques; Methylamines; Mice; Neuromuscular Junction; Neurotoxins; Tetanus Toxin; Theophylline | 1988 |
Calcium conductance and firing properties of spinal motoneurones in the turtle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Apamin; Calcium; In Vitro Techniques; Ion Channels; Motor Neurons; Neuromuscular Depolarizing Agents; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Turtles | 1988 |
Potassium currents in rat cerebellar Purkinje neurones maintained in culture in L15 (Leibovitz) medium.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Culture Media; Electric Stimulation; Ion Channels; Membrane Potentials; Potassium; Purkinje Cells; Rats; Tetraethylammonium Compounds | 1988 |
Effects of tetraethylammonium and 4-aminopyridine on the plateau potential of circular myometrium from the pregnant rat.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Electrophysiology; Female; Gallopamil; In Vitro Techniques; Ion Channels; Membrane Potentials; Myometrium; Potassium; Pregnancy; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
The effect of barium and some channel blockers on sensory discharge of the frog labyrinth posterior canal recorded at rest and during rotation.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Cobalt; Ear, Inner; Ion Channels; Rana esculenta; Tetraethylammonium Compounds | 1988 |
Dendrotoxin and 4-aminopyridine potentiate neurohypophysial hormone secretion during low frequency electrical stimulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Elapid Venoms; Electric Stimulation; In Vitro Techniques; Ion Channels; Male; Naloxone; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Vasopressins | 1988 |
Three kinetically distinct potassium channels in mouse neuroblastoma cells.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Ion Channels; Kinetics; Mice; Neuroblastoma; Potassium; Tumor Cells, Cultured | 1988 |
Interaction of forskolin with the effect of atropine on [3H]acetylcholine secretion in guinea-pig ileum myenteric plexus.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Aminopyridines; Animals; Atropine; Colforsin; Cyclic GMP; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Neuromuscular Junction | 1988 |
Ionic basis of the differential neuronal activity of guinea-pig septal nucleus studied in vitro.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Cobalt; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurons; Septal Nuclei; Tetrodotoxin; Time Factors | 1988 |
Intrinsic properties of neurones in the dorsal cochlear nucleus of mice, in vitro.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Brain; Calcium; Cochlear Nerve; In Vitro Techniques; Ion Channels; Mice; Muscarine; Neurons; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1988 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Kinetic analysis of voltage- and ion-dependent conductances in saccular hair cells of the bull-frog, Rana catesbeiana.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Hair Cells, Auditory; In Vitro Techniques; Ion Channels; Kinetics; Models, Neurological; Potassium; Rana catesbeiana; Saccule and Utricle; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
A model for electrical resonance and frequency tuning in saccular hair cells of the bull-frog, Rana catesbeiana.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Computer Simulation; Hair Cells, Auditory; In Vitro Techniques; Ion Channels; Membrane Potentials; Models, Neurological; Rana catesbeiana; Saccule and Utricle; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Inhibition of K+ permeability diminishes alpha 2-adrenoceptor mediated effects on norepinephrine release.
Topics: 4-Aminopyridine; Aminopyridines; Animals; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred Strains; Norepinephrine; Permeability; Potassium; Quinine; Receptors, Adrenergic, alpha; Tritium; Vas Deferens; Xylazine; Yohimbine | 1988 |
Mechanism of action of galanin on myenteric neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electrophysiology; Galanin; Guinea Pigs; Membrane Potentials; Myenteric Plexus; Neurons; Peptides; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Dual effect of dihydropyridines on 45Ca uptake induced by the K+ -channel blocker, 4-aminopyridin on mast cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dihydropyridines; Female; Histamine Release; Ion Channels; Mast Cells; Nifedipine; Nisoldipine; Potassium; Rats; Rats, Inbred Strains | 1988 |
Potassium channels expressed from rat brain cDNA have delayed rectifier properties.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane; Cerebral Cortex; DNA; Elapid Venoms; Electric Conductivity; Female; Gene Expression Regulation; Histamine Release; Membrane Potentials; Oocytes; Peptides; Potassium; Potassium Channels; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus | 1988 |
Glyburide blocks the relaxation response to BRL 34915 (cromakalim), minoxidil sulfate and diazoxide in vascular smooth muscle.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Antihypertensive Agents; Benzopyrans; Charybdotoxin; Cromakalim; Diazoxide; Glyburide; Male; Minoxidil; Muscle, Smooth, Vascular; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds; Vasodilation | 1989 |
Effects of charybdotoxin, a blocker of Ca2+-activated K+ channels, on motor nerve terminals.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Apamin; Calcium; Charybdotoxin; In Vitro Techniques; Membrane Potentials; Mice; Motor Endplate; Neuromuscular Junction; Potassium Channels; Scorpion Venoms | 1988 |
K+ channel and adenylate cyclase involvement in regulation of Ca2+-evoked release of [3H]dopamine from synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Aminopyridines; Animals; Calcium; Colforsin; Dopamine; Ergolines; Ethylmaleimide; In Vitro Techniques; Pertussis Toxin; Potassium Channels; Quinpirole; Rats; Synaptosomes; Tetraethylammonium Compounds; Virulence Factors, Bordetella | 1989 |
Electrophysiological investigations in adoptively transferred experimental autoimmune encephalomyelitis in the Lewis rat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Body Temperature; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Encephalomyelitis, Autoimmune, Experimental; Female; Immunization, Passive; Myelin Basic Protein; Rats; Rats, Inbred Lew; Spinal Cord; Spinal Nerve Roots | 1989 |
Effect of some potassium channel blockers on contractile responses of the rabbit aorta.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Aorta, Thoracic; Apamin; Calcium Channel Blockers; Endothelium, Vascular; Female; In Vitro Techniques; Isradipine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxadiazoles; Potassium Channels; Rabbits; Scorpion Venoms; Tetraethylammonium Compounds | 1989 |
Inward rectifying potassium channels in human malignant glioma cells.
Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Glioma; Humans; Ion Channels; Membrane Potentials; Potassium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1989 |
Potassium and sodium channels in human malignant glioma cells.
Topics: 4-Aminopyridine; Aminopyridines; Calcium; Cell Line; Glioma; Humans; Ion Channels; Potassium; Sodium; Tetraethylammonium Compounds; Tumor Cells, Cultured | 1989 |
The role of potassium channels in Schwann cell proliferation in Wallerian degeneration of explant rabbit sciatic nerves.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Female; Gramicidin; Male; Membrane Potentials; Microbial Collagenase; Mitosis; Nerve Degeneration; Potassium Channels; Quinine; Rabbits; Schwann Cells; Sciatic Nerve; Tetraethylammonium Compounds; Veratridine; Wallerian Degeneration | 1989 |
Release of acetylcholine from tissue slices of the rat nucleus basalis magnocellularis.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Calcium; Choline O-Acetyltransferase; In Vitro Techniques; Male; Potassium; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Spinal Cord | 1989 |
Comparison of vestibular and auditory startle responses in the rat and cat.
Topics: 4-Aminopyridine; Acoustic Stimulation; Aminopyridines; Animals; Auditory Pathways; Cats; Efferent Pathways; Hindlimb; Motor Neurons; Muscles; Rats; Reaction Time; Reflex, Startle; Vestibule, Labyrinth | 1989 |
Rate-limiting step for transmission at excitatory synapses in hippocampus.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Synaptic Transmission | 1989 |
Na+, K+ and Ca2+ currents in identified leech neurones in culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cadmium; Calcium Channels; Cations, Divalent; Cells, Cultured; Electric Conductivity; Kinetics; Leeches; Manganese; Membrane Potentials; Nervous System; Nervous System Physiological Phenomena; Neurons; Neurons, Afferent; Potassium Channels; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
A role for potassium channels in the regulation of cortical muscarinic acetylcholine receptors in an in vitro slice preparation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Carbachol; Cerebral Cortex; Electric Conductivity; Homeostasis; In Vitro Techniques; Kinetics; Male; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine | 1989 |
Effect of calcium on synaptic facilitation by potassium channel blockers in superior cervical ganglion of rat.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cesium; Chlorides; Ganglia, Sympathetic; Guanidine; Guanidines; Male; Potassium Channels; Rats; Rats, Inbred Strains; Synapses; Tetraethylammonium Compounds | 1989 |
Two components of transient outward current in canine ventricular myocytes.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Caffeine; Calcium; Cells, Cultured; Dogs; Electrophysiology; Heart Conduction System; Heart Ventricles; Kinetics; Manganese; Myocardium; Ryanodine; Sarcoplasmic Reticulum; Ventricular Function | 1989 |
Expression of a cloned rat brain potassium channel in Xenopus oocytes.
Topics: 4-Aminopyridine; Amino Acid Sequence; Aminopyridines; Animals; Base Sequence; Brain; Cloning, Molecular; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Oocytes; Potassium; Potassium Channels; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Xenopus | 1989 |
Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes.
Topics: 4-Aminopyridine; Aminoacridines; Aminopyridines; Animals; Choline; Choline O-Acetyltransferase; Corpus Striatum; Hippocampus; Male; Rats; Rats, Inbred Strains; Synaptosomes; Tacrine | 1989 |
Effect of 4-aminopyridine on the postsynaptic action of polymyxin B.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Carbachol; In Vitro Techniques; Male; Motor Endplate; Neostigmine; Neuromuscular Depolarizing Agents; Polymyxin B; Polymyxins; Rats; Rats, Inbred Strains; Respiratory Muscles; Synapses; Tubocurarine | 1989 |
The influence of ouabain on twitch contractions in the presence of veratridine.
Topics: 4-Aminopyridine; Aconitine; Aminopyridines; Animals; Caffeine; Electric Stimulation; Male; Mice; Mice, Inbred Strains; Monensin; Muscle Contraction; Ouabain; Potassium Chloride; Respiratory Muscles; Tetraethylammonium Compounds; Tubocurarine; Veratridine; Veratrine | 1989 |
Noradrenergic, purinergic, and cholinergic transmission in the mouse vas deferens: influence of field-stimulation parameters, reserpinization, 6-hydroxydopamine and 4-aminopyridine.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Atropine; Electric Stimulation; Hydroxydopamines; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Neostigmine; Norepinephrine; Oxidopamine; Prazosin; Reserpine; Synaptic Transmission; Vas Deferens | 1989 |
Protein kinase C activators reduce the inositol trisphosphate-induced outward current and the Ca2+-activated outward current in identified neurons of Aplysia.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Calcium; Diglycerides; Electric Conductivity; Ganglia; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Neurons; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Second Messenger Systems; Sugar Phosphates; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
The transient potassium current, the A-current, is involved in spike frequency adaptation in rat amygdala neurons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Amygdala; Animals; In Vitro Techniques; Male; Potassium; Rats | 1989 |
Effect of 4-aminopyridine on axonal conduction-block in chronic spinal cord injury.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cats; Disease Models, Animal; Female; Neural Conduction; Spinal Cord Injuries; Temperature | 1989 |
Ca2+ channel blockers prevent seizures induced by a class of K+ channel inhibitors.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Anticonvulsants; Calcium Channel Blockers; Elapid Venoms; Electrocardiography; Hippocampus; Iodine Radioisotopes; Male; Peptides; Potassium Channels; Rats; Rats, Inbred Strains | 1989 |
Different actions of a short-acting barbiturate on sodium and potassium conductances in invertebrate and vertebrate neurons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cells, Cultured; Chick Embryo; Electric Conductivity; Ganglia, Spinal; Leeches; Methohexital; Neurons; Potassium Channels; Saxitoxin; Sodium Channels; Species Specificity; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cadmium; Cadmium Chloride; Calcium; Carbachol; Cobalt; Conditioning, Classical; Egtazic Acid; Electroshock; Hippocampus; In Vitro Techniques; Male; Pyramidal Tracts; Rabbits; Reference Values; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1989 |
Differential effects of 4-aminopyridine on acetylcholine release triggered by K+ depolarization, veratridine, or A23187 in rat cerebral cortical synaptosomes.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcimycin; Cerebral Cortex; Cholinesterase Inhibitors; Kinetics; Male; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Veratridine; Veratrine | 1989 |
Potassium channel blocking agents induce occasional spontaneous action potentials and multiquantal ATP release in sympathetic nerve terminals.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Aminopyridines; Animals; Guinea Pigs; Male; Mice; Nerve Endings; Potassium Channels; Sympathetic Nervous System; Tetraethylammonium Compounds; Vas Deferens | 1989 |
Release of vasoactive intestinal peptide in mouse cerebral cortex: evidence for a role of arachidonic acid metabolites.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Lipoxygenase Inhibitors; Male; Melitten; Mice; Quinacrine; Tetrodotoxin; Vasoactive Intestinal Peptide | 1989 |
Failure of non-adrenergic transmission in the rat vas deferens.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Electric Stimulation; Epididymis; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Phentolamine; Potassium Chloride; Prostate; Rats; Rats, Inbred Strains; Reserpine; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens | 1989 |
Hypoxic changes in hippocampal neurons.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Apamin; Caffeine; Calcium; Egtazic Acid; Electric Stimulation; Hippocampus; Hypoxia; Membrane Potentials; Neuroglia; Neuromuscular Depolarizing Agents; Neurons; Nitrogen; Quinine; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tolbutamide | 1989 |
The effects of tetraethylammonium during twitch and tetanic stimulation of the phrenic nerve diaphragm preparation in the rat.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Diaphragm; Electric Stimulation; Electromyography; Female; Hemicholinium 3; Male; Microelectrodes; Motor Endplate; Muscle Contraction; Phrenic Nerve; Potassium; Rats; Rats, Inbred Strains; Respiratory Muscles; Tetraethylammonium Compounds | 1989 |
Potassium channel blockers differentially affect carbachol and (-)-N6-phenylisopropyladenosine on guinea-pig atria.
Topics: 4-Aminopyridine; Adenosine; Aminopyridines; Animals; Carbachol; Electric Stimulation; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenylisopropyladenosine; Potassium Channels; Tetraethylammonium Compounds | 1989 |
The effects of 4-aminopyridine on the cat spinal cord: rhythmic antidromic discharges recorded from the dorsal roots.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cats; Electric Stimulation; Motor Neurons; Muscles; Neurons, Afferent; Skin; Spinal Cord; Spinal Nerve Roots | 1989 |
Unitary discharges in dorsal and ventral roots after the administration of 4-aminopyridine in the cat.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cats; Electric Stimulation; Muscles; Neural Conduction; Neurons, Afferent; Skin; Spinal Nerve Roots | 1989 |
The mechanism of the rate-dependent changes of the conducted action potential in rabbit ventricle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cobalt; Heart Ventricles; In Vitro Techniques; Rabbits | 1989 |
Presynaptic calcium currents and facilitation of serotonin release at synapses between cultured leech neurones.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Barium; Calcium; Calcium Channels; Cations, Divalent; Cells, Cultured; Electrophysiology; Leeches; Neurons; Serotonin; Sodium; Strontium; Synapses; Tetraethylammonium; Tetraethylammonium Compounds | 1989 |
K+-channel blockade in trigeminal root ganglion neurons: effects on membrane outward currents.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane; Cesium; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Membrane Potentials; Neurons; Parasympathomimetics; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Trigeminal Ganglion; Trigeminal Nerve | 1989 |
Consequences of 4-aminopyridine applications to trigeminal root ganglion neurons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cell Membrane; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Neurons; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Trigeminal Ganglion; Trigeminal Nerve | 1989 |
[Effect of tractotomy on the reflex activity of the lumbar segment of the spinal cord severed after sectioning of the sciatic nerve in the rat].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Evoked Potentials; Female; Lumbosacral Region; Motor Neurons; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Reflex; Sciatic Nerve; Spinal Cord | 1989 |
Voltage-activated K+ conductances in freshly isolated embryonic chicken osteoclasts.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Cesium; Chick Embryo; Electric Conductivity; Membrane Potentials; Osteoclasts; Potassium Channels | 1989 |
Depressant effect of magnesium on early afterdepolarizations and triggered activity induced by cesium, quinidine, and 4-aminopyridine in canine cardiac Purkinje fibers.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cardiovascular Agents; Cesium; Depression, Chemical; Dogs; Female; Heart Conduction System; In Vitro Techniques; Magnesium; Male; Purkinje Fibers; Quinidine; Tachycardia | 1989 |
Subtypes of K+ channels differentiated by the effect of K+ channel openers upon K+ channel blocker-induced seizures.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Elapid Venoms; Injections, Intraventricular; Male; Neurotoxins; Peptides; Potassium Channels; Rats; Rats, Inbred Strains; Seizures | 1989 |
The effect of 4-aminopyridine on action potential shape and firing pattern of rat dorsal root ganglion neurones.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Female; Ganglia, Spinal; Neurons, Afferent; Potassium Channels; Rats | 1989 |
Effects of potassium channel blockers on differentiation of Dictyostelium discoideum.
Topics: 4-Aminopyridine; Aminopyridines; Dictyostelium; In Vitro Techniques; Potassium Channels; Quinine; Tetraethylammonium Compounds | 1989 |
Dendrotoxin, 4-aminopyridine, and beta-bungarotoxin act at common loci but by two distinct mechanisms to induce Ca2+-dependent release of glutamate from guinea-pig cerebrocortical synaptosomes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bungarotoxins; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Elapid Venoms; Glutamates; Glutamic Acid; Guinea Pigs; Membrane Potentials; Potassium Chloride; Strontium; Synaptosomes | 1989 |
Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cerebral Cortex; Chlorides; In Vitro Techniques; Ketamine; Magnesium; Membrane Potentials; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Time Factors; Valine | 1989 |
Effects of potassium channel blockade on endogenous glutamate release from cerebellar slices.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cerebellum; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Potassium Channels; Quaternary Ammonium Compounds; Quinine; Rats; Rats, Inbred Strains | 1989 |
A comparison of the actions of 4-aminopyridine, caffeine and quinine on the toad isolated rectus abdominis muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bufonidae; Caffeine; Egtazic Acid; In Vitro Techniques; Manganese; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium; Procaine; Quinine; Verapamil | 1989 |
Effects of low concentrations of 4-aminopyridine on CA1 pyramidal cells of the hippocampus.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicuculline; Central Nervous System Stimulants; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1989 |
Alpha 2-adrenoceptor agonist-mediated inhibition of [3H]noradrenaline release from rat hippocampus is reduced by 4-aminopyridine, but that caused by an adenosine analogue or omega-conotoxin is not.
Topics: 4-Aminopyridine; Adenosine; Adrenergic alpha-Agonists; Aminopyridines; Animals; Brimonidine Tartrate; Cadmium; Cadmium Chloride; Conotoxins; Hippocampus; Male; Mollusk Venoms; Norepinephrine; Phenylisopropyladenosine; Quinoxalines; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Effects of cadmium on quantal transmitter release and ultrastructure of frog motor nerve endings.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Cadmium; Diaphragm; In Vitro Techniques; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Rana esculenta; Respiratory Muscles; Synaptic Transmission; Tetrodotoxin | 1989 |
[The antagonism of ketamine/xylazine anesthesia ("Hellabrunn mixture") in wild zoo ruminants].
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Animals, Zoo; Central Nervous System Stimulants; Ketamine; Ruminants; Thiazines; Tolazoline; Xylazine; Yohimbine | 1989 |
Threshold of synaptically elicited cortical spreading depression: drug-induced changes in rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cerebral Cortex; Electroencephalography; Potassium; Pyrimidines; Rats; Synapses | 1985 |
Barium action potentials in regenerating axons of the lamprey spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Barium; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channels; Isoquinolines; Lampreys; Microelectrodes; Nerve Regeneration; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
beta-Adrenergic induced K+ current in Xenopus oocytes: role of cAMP, inhibition by muscarinic agents.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine; Aminobenzoates; Aminopyridines; Animals; Atropine; Calcimycin; Colforsin; Cyclic AMP; Diterpenes; Female; Isoproterenol; Oocytes; Phosphodiesterase Inhibitors; Potassium; Receptors, Adrenergic, beta; Tetraethylammonium Compounds; Xenopus laevis | 1985 |
Light-evoked depolarizations in the retina of Strombus: role of sodium and potassium ions.
Topics: 4-Aminopyridine; Adaptation, Physiological; Aminopyridines; Animals; Hydrogen-Ion Concentration; Ion Channels; Lithium; Membrane Potentials; Neurons; Photic Stimulation; Potassium; Retina; Snails; Sodium; Tetrodotoxin | 1985 |
A fast transient outward current in the rat sympathetic neurone studied under voltage-clamp conditions.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Electric Conductivity; Female; Ganglia, Sympathetic; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurons; Potassium; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Unusual potassium channels mediate nonadrenergic noncholinergic nerve-mediated inhibition in opossum esophagus.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Apamin; Autonomic Nervous System; Electric Stimulation; Esophagus; Female; Ion Channels; Male; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Neuromuscular Junction; Opossums; Quinine; Tetraethylammonium Compounds | 1985 |
Possible allosteric interaction of 4-aminopyridine with rat brain muscarinic acetylcholine receptors.
Topics: 4-Aminopyridine; Allosteric Site; Aminopyridines; Animals; Brain; Female; In Vitro Techniques; Ion Channels; Neuromuscular Depolarizing Agents; Potassium; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Tritium | 1985 |
The slow calcium-dependent potassium current in a myenteric neurone of the guinea-pig ileum.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Myenteric Plexus; Neurons; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1985 |
Calcium-activated potassium channels in isolated presynaptic nerve terminals from rat brain.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcimycin; Calcium; Female; In Vitro Techniques; Ion Channels; Lanthanum; Membrane Potentials; Potassium; Quinine; Radioisotopes; Rats; Rubidium; Synaptosomes | 1985 |
Transient voltage and calcium-dependent outward currents in hippocampal CA3 pyramidal neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Electrophysiology; Equipment and Supplies; Guinea Pigs; Hippocampus; Ion Channels; Male; Manganese; Neurons; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1985 |
Differential blockage of two types of potassium channels in the crab giant axon.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Brachyura; Ion Channels; Kinetics; Membrane Potentials; Nerve Fibers; Neuromuscular Depolarizing Agents; Potassium; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Distribution of the 4-aminopyridine derivative 3-methoxy-4-aminopyridine in mice.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Autoradiography; Carbon Radioisotopes; Injections, Intravenous; Male; Mice; Tissue Distribution | 1989 |
Block of potassium channels and facilitation of acetylcholine release at the neuromuscular junction by the venom of the scorpion, Pandinus imperator.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Amifampridine; Aminopyridines; Animals; Chickens; Electrophysiology; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Potassium Channels; Scorpion Venoms; Stimulation, Chemical | 1989 |
[Antagonistic effect of 4-aminopyridine derivatives on dTc induced block].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Male; Neuromuscular Junction; Rats; Rats, Inbred Strains; Tubocurarine | 1989 |
Electrophysiological function of the delayed rectifier (IK) in bullfrog sympathetic ganglion neurones.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Barium; Calcium; Ganglia, Sympathetic; In Vitro Techniques; Neurons; Potassium Channels; Rana catesbeiana | 1989 |
Modulation of stimulation-evoked release of newly formed acetylcholine from mouse hemidiaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Aminopyridines; Animals; Atropine; Calcium; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Mice; Neuromuscular Junction; Oxotremorine; Tetrodotoxin; Theophylline; Xylazine | 1987 |
Features of 4-aminopyridine sensitive outward current observed in single smooth muscle cells from the rabbit pulmonary artery.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Drug Interactions; Female; In Vitro Techniques; Male; Manganese; Membrane Potentials; Pulmonary Artery; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Vasoconstriction | 1987 |
Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Female; Lysophosphatidylcholines; Motor Activity; Myelin Sheath; Nerve Fibers, Myelinated; Rats; Sensation; Spinal Nerve Roots | 1987 |
Fluorescence-activated cell sorting of embryonic mouse and rat motoneurons and their long-term survival in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Antibodies; Cell Separation; Cell Survival; Flow Cytometry; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Motor Neurons; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Time Factors | 1987 |
Presynaptic effects of 4-aminopyridine and changes following a single giant impulse at the Torpedo nerve-electroplaque junction.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aminopyridines; Animals; Electric Organ; Nerve Endings; Phosphocreatine; Synapses; Torpedo | 1987 |
[Complex pathogenetic therapy of experimental botulism].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Botulism; Drug Therapy, Combination; Guanylthiourea; Male; Mice; Thiourea | 1987 |
Release of endogenous ATP during sympathetic nerve stimulation.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Phenylephrine; Prazosin; Sympathetic Nervous System; Tetrodotoxin; Vas Deferens | 1987 |
Transient outward current prominent in canine ventricular epicardium but not endocardium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Dogs; Endocardium; Heart Conduction System; Heart Ventricles; Microelectrodes; Pericardium; Strontium; Time Factors | 1988 |
Pre- and postsynaptic K+ and Ca2+ fluxes in area CA1 of the rat hippocampus in vitro: effects of Ni2+, TEA and 4-AP.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Culture Media; Hippocampus; In Vitro Techniques; Nickel; Osmolar Concentration; Potassium; Rats; Synapses; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Saxitoxin differentiates between two types of Na+-dependent potentials in the Retzius cell of hirudinid leeches.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; In Vitro Techniques; Leeches; Saxitoxin; Sodium; Species Specificity; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Effect of intravenously-administered putative and potential antagonists of ethanol on sleep time in ethanol-narcotized mice.
Topics: 4-Aminopyridine; Alcoholic Intoxication; Aminophylline; Aminopyridines; Amphetamine; Animals; Azides; Benzodiazepines; Dextroamphetamine; Doxapram; Ethanol; Male; Mice; Naloxone; Physostigmine; Propranolol; Sleep; Thyrotropin-Releasing Hormone; Yohimbine | 1988 |
Cation transport by pancreatic beta-cells: effect of 4-aminopyridine on 86Rb+ and 45Ca2+ fluxes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Radioisotopes; Cell Membrane Permeability; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Potassium; Rats; Rats, Inbred Strains; Rubidium Radioisotopes | 1987 |
Delayed rectifier K+ current in embryonic chick heart ventricle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Barium; Barium Compounds; Cesium; Chick Embryo; Chlorides; Culture Techniques; Electrophysiology; Heart; Potassium; Reference Values; Tetraethylammonium; Tetraethylammonium Compounds; Ventricular Function | 1988 |
Study on the neuromuscular action of 4-aminopyridine in the mouse diaphragm.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Calcium; Diaphragm; Female; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Neural Conduction; Neuromuscular Junction | 1987 |
Inhibition by quinine of endothelium-dependent relaxation of rabbit aortic strips.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aorta, Thoracic; Barium; Barium Compounds; Calcimycin; Chlorides; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Quaternary Ammonium Compounds; Quinine; Rabbits; Sodium Nitrite; Tetraethylammonium Compounds | 1987 |
Multiple potassium conductances at the mammalian motor nerve terminal.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Cardiovascular Agents; Electric Stimulation; In Vitro Techniques; Mice; Motor Endplate; Motor Neurons; Nerve Endings; Potassium | 1987 |
Tetraethylammonium ions and 4-aminopyridine prevent opioid inhibition of neurohypophysial oxytocin release.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Etorphine; Female; Naloxone; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1987 |
Higher susceptibility of taurine-deficient rats to seizures induced by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cerebral Cortex; Rats; Seizures; Taurine | 1987 |
Augmentation by 4-aminopyridine of vestibulospinal free fall responses in chronic spinal-injured cats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Chronic Disease; Efferent Pathways; Electromyography; Muscles; Reflex; Spinal Cord Injuries; Vestibule, Labyrinth | 1987 |
Differential effects of 4-aminopyridine and 2,4-diaminopyridine on the in vivo release of acetylcholine and dopamine in freely moving rats measured by intrastriatal dialysis.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Brain; Corpus Striatum; Dialysis; Dopamine; Injections; Male; Rats; Rats, Inbred Strains; Tetrodotoxin | 1988 |
Long-term potentiation and 4-aminopyridine-induced changes in protein and lipid phosphorylation in the hippocampal slice.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calmodulin; GAP-43 Protein; Hippocampus; In Vitro Techniques; Kinetics; Lipid Metabolism; Models, Neurological; Nerve Tissue Proteins; Neuronal Plasticity; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoproteins; Rats; Synaptic Transmission | 1986 |
Transport pathways in rat lingual epithelium.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Biological Transport, Active; Epithelium; Glucose; In Vitro Techniques; Membrane Potentials; Osmosis; Potassium Chloride; Rats; Rats, Inbred Strains; Sodium Chloride; Sucrose; Tongue | 1988 |
Sensitivity to 4-aminopyridine observed in mammalian sciatic nerves during acute pyridoxine-induced sensory neuropathy and recovery.
Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Aminopyridines; Animals; Female; Nerve Fibers, Myelinated; Nervous System Diseases; Pyridoxine; Rats; Rats, Inbred Strains; Reaction Time; Sciatic Nerve; Sensation; Spinal Nerve Roots | 1988 |
Effects of neostigmine, edrophonium, 4-aminopyridine and their combinations.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Drug Combinations; Drug Synergism; Edrophonium; In Vitro Techniques; Male; Neostigmine; Neuromuscular Nondepolarizing Agents; Pancuronium; Rats; Rats, Inbred Strains | 1988 |
Miniature endplate potentials as a tool in neurotoxicology.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Evoked Potentials; In Vitro Techniques; Mice; Motor Endplate; Neural Conduction; Neuromuscular Junction; Organometallic Compounds; Phrenic Nerve | 1988 |
Adenosine antagonists combined with 4-aminopyridine cause partial recovery of synaptic transmission in low Ca media.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Deaminase; Aminopyridines; Animals; Calcium; Electric Stimulation; Hippocampus; In Vitro Techniques; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1988 |
Voltage-gated potassium currents in cultured ovine oligodendrocytes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Survival; Cells, Cultured; Cesium; Electrophoresis; Kinetics; Membrane Potentials; Neuroglia; Oligodendroglia; Potassium; Sheep; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Comparison of the antagonistic effects of yohimbine and 4-aminopyridine in dogs under xylazine-ketamine anesthesia.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Dissociative; Animals; Blood Pressure; Cardiovascular Agents; Dogs; Drug Antagonism; Drug Interactions; Female; Injections, Intramuscular; Injections, Intravenous; Ketamine; Male; Thiazines; Xylazine; Yohimbine | 1987 |
The effect of 4-aminopyridine on micturition reflex in normal or capsaicin-desensitized rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Capsaicin; Male; Rats; Rats, Inbred Strains; Reference Values; Reflex; Urinary Bladder; Urination | 1988 |
Examination of the role of calcium in the adrenaline-induced hyperpolarization of bullfrog sympathetic neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Apamin; Bufonidae; Caffeine; Calcium; Dantrolene; Electrophysiology; Epinephrine; Gallic Acid; Neurons; Potassium; Quinidine; Sympathetic Nervous System; Tetraethylammonium Compounds; Tubocurarine | 1988 |
4-Aminopyridine sensitive transient outward current in dog ventricular fibres.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dogs; Electrophysiology; Heart; Heart Ventricles; Time Factors | 1988 |
4-Aminopyridine reduces vagal-stimulated gastric acid secretion in the rat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Deoxyglucose; Depression, Chemical; Gastric Acid; In Vitro Techniques; Injections, Intraventricular; Rats; Vagus Nerve | 1988 |
Potassium current activated by depolarization of dissociated neurons from adult guinea pig hippocampus.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cadmium; Cobalt; Electric Conductivity; Guinea Pigs; Hippocampus; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Potassium; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Effects of 2-(4-phenylpiperidino)cyclohexanol (AH5183) and barium ions on frog neuromuscular transmission.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; In Vitro Techniques; Magnesium; Motor Endplate; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Phencyclidine; Piperidines; Ranidae; Strontium; Synaptic Transmission | 1988 |
The influence of aminopyridines on Ca2+-dependent evoked release of acetylcholine from rat cortex slices.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Calcium; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1988 |
A depolarizing inhibitory postsynaptic potential activated by synaptically released gamma-aminobutyric acid under physiological conditions in rat hippocampal pyramidal cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Male; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1988 |
Inhibition of the generation of cytotoxic lymphocytes by potassium ion channel blockers.
Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Cytotoxicity, Immunologic; Humans; Interleukin-2; Isoantigens; Kinetics; Potassium Channels; T-Lymphocytes, Cytotoxic; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Stage-specific distinctions in potassium channel blocker control of T-lymphocyte activation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Kinetics; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Potassium Channels; Quinine; Receptors, Mitogen; T-Lymphocytes; Tetraethylammonium Compounds; Verapamil | 1988 |
ATP-sensitive K+ channels are altered in hypertrophied ventricular myocytes.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Calcium; Cardiomegaly; Cats; Dose-Response Relationship, Drug; Electric Conductivity; Heart Ventricles; Membrane Potentials; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Changes in cytosolic free calcium with 1,2,3,4-tetrahydro-5-aminoacridine, 4-aminopyridine and 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Amifampridine; Aminoacridines; Aminopyridines; Animals; Brain; Calcium; Cytosol; In Vitro Techniques; Mice; Synaptosomes; Tacrine | 1988 |
Effects of 4-aminopyridine in experimental CNS demyelination.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Central Nervous System Diseases; Demyelinating Diseases; Dose-Response Relationship, Drug; Electric Stimulation; Male; Neural Conduction; Rats; Rats, Inbred Strains; Seizures | 1988 |
Delayed and fast transient potassium currents in rat neocortical neurons in cell culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Cerebral Cortex; Electric Conductivity; Neurons; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1988 |
4-Aminopyridine induces a long-lasting depolarizing GABA-ergic potential in human neocortical and hippocampal neurons maintained in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Bicuculline; Cerebral Cortex; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Humans; In Vitro Techniques; Neurons | 1988 |
Voltage-clamp analysis of a transient potassium current in rat neostriatal neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Corpus Striatum; Electric Stimulation; Membrane Potentials; Potassium; Rats; Rats, Inbred Strains | 1988 |
[Possible role of the potential-dependent potassium channels in the generation of responses of the pacinian corpuscles].
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cats; Cell Membrane; Mechanoreceptors; Neuromuscular Depolarizing Agents; Pacinian Corpuscles; Potassium Channels; Ranvier's Nodes; Tetraethylammonium Compounds | 1988 |
Comparative effects of K+ channel blockade on the vasorelaxant activity of cromakalim, pinacidil and nicorandil.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Benzopyrans; Cardiovascular Agents; Cromakalim; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Procaine; Pyrroles; Rabbits; Rubidium Radioisotopes; Tetraethylammonium Compounds; Vasodilator Agents | 1988 |
Reversal of xylazine-induced sedation in llamas, using doxapram or 4-aminopyridine and yohimbine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Artiodactyla; Camelids, New World; Doxapram; Female; Heart Rate; Hypnotics and Sedatives; Male; Respiration; Thiazines; Xylazine; Yohimbine | 1986 |
Optical recording of electrical activity from axons and glia of frog optic nerve: potentiometric dye responses and morphometrics.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Benzenesulfonates; Electric Stimulation; Fluorescent Dyes; Neuroglia; Optic Nerve; Oxazoles; Oxazolone; Photic Stimulation; Rana pipiens; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Tetrodotoxin | 1988 |
Effects of Ca2+ on the transient outward current of single isolated Helix central neurones.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cholinesterase Inhibitors; Helix, Snails; In Vitro Techniques; Membrane Potentials; Neurons | 1988 |
Development of 4-AP and TEA sensitivities in mammalian myelinated nerve fibers.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Nerve Fibers, Myelinated; Potassium Channels; Rats; Rats, Inbred Strains; Reference Values; Sciatic Nerve; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
The kinetics of quantal releases during end-plate currents at the frog neuromuscular junction.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; In Vitro Techniques; Kinetics; Motor Endplate; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Rana pipiens; Temperature | 1988 |
Effects of tetraethylammonium on the depolarizing after-potential and passive properties of lizard myelinated axons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Gallamine Triethiodide; In Vitro Techniques; Lizards; Membrane Potentials; Muscles; Nerve Fibers, Myelinated; Neuromuscular Depolarizing Agents; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1988 |
The development of voltage-dependent ionic conductances in murine spinal cord neurones in culture.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Calcium Channels; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; Membrane Potentials; Mice; Mice, Inbred Strains; Neurons; Potassium Channels; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Physostigmine stimulates phosphoinositide breakdown in the rat neostriatum.
Topics: 4-Aminopyridine; Acetylcholinesterase; Aminopyridines; Animals; Cholinesterase Inhibitors; Corpus Striatum; Male; Parasympathomimetics; Phosphatidylinositols; Physostigmine; Rats; Rats, Inbred Strains | 1988 |
Differential effects of potassium channel blockers on neurohypophysial release of oxytocin and vasopressin. Evidence for frequency-dependent interaction with the endogenous opioid inhibition of oxytocin release.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Benzopyrans; Cromakalim; Electric Stimulation; Endorphins; Female; Naloxone; Oxytocin; Pituitary Gland, Posterior; Potassium Channels; Pyrroles; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Vasopressins | 1988 |
Effect of K+ channel blockers on anti-immunoglobulin-induced murine B cell proliferation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; DNA; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Potassium Channels; Protein Biosynthesis; Quinine; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Comparison of potassium currents in rabbit atrial and ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Electric Stimulation; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Membrane Potentials; Potassium Channels; Rabbits; Time Factors | 1988 |
Characterization of membrane currents in dissociated adult rat pineal cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Calcium Channels; In Vitro Techniques; Male; Membrane Potentials; Microscopy, Electron, Scanning; Pineal Gland; Potassium Channels; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1988 |
Guanosine 5'-triphosphate analogue activates potassium current modulated by neurotransmitters in Aplysia neurones.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Aplysia; Arecoline; Cyclic AMP; FMRFamide; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Neurons; Neuropeptides; Potassium; Potassium Channels; Serotonin; Tetraethylammonium; Tetraethylammonium Compounds; Thionucleotides; Time Factors | 1988 |
Scope and mechanisms of control of stimulus-secretion coupling in single varicosities of sympathetic nerves.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Adrenergic Fibers; Aminopyridines; Animals; Calcium; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Neurons; Norepinephrine; Phentolamine; Receptors, Adrenergic, alpha; Tetraethylammonium; Tetraethylammonium Compounds; Vas Deferens | 1985 |
Effect of xylazine on heart rate and arterial blood pressure in conscious dogs, as influenced by atropine, 4-aminopyridine, doxapram, and yohimbine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Blood Pressure; Central Nervous System Stimulants; Dogs; Doxapram; Drug Interactions; Heart Rate; Male; Thiazines; Xylazine; Yohimbine | 1985 |
Responses evoked by electrical stimulation, adenosine triphosphate, adenosine and 4-aminopyridine in taenia caeci of the guinea-pig.
Topics: 4-Aminopyridine; Adenosine; Adenosine Triphosphate; Aminopyridines; Animals; Cecum; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Neurotransmitter Agents; Purines; Synaptic Transmission | 1985 |
Antagonism of xylazine sedation with yohimbine, 4-aminopyridine, and doxapram in dogs.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arousal; Central Nervous System Stimulants; Dogs; Doxapram; Drug Combinations; Female; Immobilization; Locomotion; Male; Thiazines; Xylazine; Yohimbine | 1985 |
A comparison of the effects of 4-dimethylaminopyridine and 4-aminopyridine on isolated cardiac and skeletal muscle preparations.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Diaphragm; Female; Gallopamil; Guinea Pigs; Heart Atria; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; Myocardial Contraction; Neuromuscular Junction; Nifedipine; Norepinephrine; Oxidopamine; Rats; Reserpine; Synaptic Transmission; Tubocurarine | 1985 |
Reversal of thiopental-induced anesthesia by 4-aminopyridine, yohimbine, and doxapram in dogs pretreated with xylazine or acepromazine.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, General; Animals; Arousal; Central Nervous System Stimulants; Dogs; Doxapram; Female; Heart Rate; Locomotion; Male; Preanesthetic Medication; Respiration; Thiazines; Thiopental; Xylazine; Yohimbine | 1985 |
The mode of action of 4-aminopyridine on the chronotropic and inotropic responses in the isolated, blood-perfused dog heart.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Dogs; Heart; Heart Rate; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Myocardial Contraction; Perfusion; Sinoatrial Node; Tetrodotoxin | 1985 |
Use of yohimbine and 4-aminopyridine to antagonize xylazine-induced immobilization in North American Cervidae.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Central Nervous System Stimulants; Deer; Immobilization; Thiazines; Xylazine; Yohimbine | 1985 |
Mechanism of the calcium-dependent stimulation of transmitter release by 4-aminopyridine in synaptosomes.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Brain; Calcium; Choline; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Sodium; Synaptosomes; Tetrodotoxin; Tritium | 1985 |
A comparison of the antagonisms by neostigmine and diaminopyridine against the neuromuscular block caused by cobrotoxin and (+)-tubocurarine.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Antidotes; Cobra Neurotoxin Proteins; Diaphragm; Drug Synergism; Female; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Neostigmine; Neuromuscular Blocking Agents; Phrenic Nerve; Tubocurarine | 1986 |
Antagonism of non-depolarising neuromuscular blockade by aminopyridines in cats.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Androstane-3,17-diol; Animals; Cats; Male; Neuromuscular Nondepolarizing Agents; Pancuronium; Pipecuronium; Piperazines; Sciatic Nerve; Vecuronium Bromide | 1986 |
Effects of toxin II from the sea anemone Anemonia sulcata on contractile and electrical responses of frog skeletal muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Cnidarian Venoms; Formamides; In Vitro Techniques; Isometric Contraction; Membrane Potentials; Muscle Contraction; Muscles; Rana esculenta; Rana temporaria | 1986 |
Antagonism of xylazine-induced depression of shuttle-avoidance responses in dogs by administration of 4-aminopyridine, doxapram, or yohimbine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Avoidance Learning; Central Nervous System Stimulants; Depression, Chemical; Dogs; Doxapram; Male; Thiazines; Xylazine; Yohimbine | 1986 |
Electroencephalographic and behavioral changes produced by 5 beta progestins and its antagonism by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Central Nervous System Stimulants; Electroencephalography; Male; Progestins; Rats | 1985 |
Animal models of Alzheimer's disease: behavior, pharmacology, transplants.
Topics: 4-Aminopyridine; Alzheimer Disease; Aminopyridines; Animals; Behavior, Animal; Brain; Disease Models, Animal; Fetus; Growth Substances; Humans; Nerve Growth Factors; Nerve Tissue; Nerve Tissue Proteins; Nervous System Diseases; Norepinephrine; Parasympathetic Nervous System; Physostigmine; Somatostatin | 1986 |
Nicotinic antagonists produce differing amounts of tetanic fade in the isolated diaphragm of the rat.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Diaphragm; Electric Stimulation; Erabutoxins; Ganglionic Blockers; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Nondepolarizing Agents; Rats; Rats, Inbred Strains | 1986 |
Barium spikes are generated in the spines of the sea urchin Diadema antillarum.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Barium; Calcium; Edetic Acid; Egtazic Acid; Sea Urchins; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Differences in presynaptic action of 4-aminopyridine and tetraethylammonium at frog neuromuscular junction.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; In Vitro Techniques; Neuromuscular Junction; Neurotransmitter Agents; Rana pipiens; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
Quantal currents evoked by graded intracellular depolarization of crayfish motor axon terminals.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Astacoidea; Axons; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Neurotransmitter Agents; Tetrodotoxin | 1987 |
Effects of ketamine and (+)cyclazocine on 4-aminopyridine and "magnesium free" epileptogenic activity in hippocampal slices of rats.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aminopyridines; Animals; Aspartic Acid; Cyclazocine; Epilepsy; Hippocampus; Ketamine; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Transmission; Valine | 1987 |
Differential alteration of dopamine, acetylcholine, and glutamate release during anoxia and/or 3,4-diaminopyridine treatment.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Calcium; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Hypoxia; In Vitro Techniques; Male; Mice; Potassium | 1987 |
Action of mefloquine on toad isolated rectus abdominis muscle.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Antimalarials; Bufonidae; Calcium; In Vitro Techniques; Mefloquine; Muscle Contraction; Muscle, Smooth; Quinolines | 1988 |
The actions of phenol and pentachlorophenol (PCP) on axonal conduction, ganglionic synaptic transmission, and the effect of pH changes.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Anura; Axons; Chlorophenols; Ganglia; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Neural Conduction; Pentachlorophenol; Phenols; Procaine; Synapses | 1988 |
Effects of potassium channel-blocking agents on neurons in the inferior mesenteric ganglion in guinea-pig.
Topics: 4-Aminopyridine; Action Potentials; Adrenergic Fibers; Aminopyridines; Animals; Barium; Enkephalin, Leucine; Ganglia; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Membrane Potentials; Mesentery; Potassium Channels; Tetraethylammonium Compounds | 1988 |
Endogenous dopamine and dopaminergic agonists modulate synaptic excitation in neostriatum: intracellular studies from naive and catecholamine-depleted rats.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Amphetamines; Animals; Benzazepines; Bromocriptine; Catecholamines; Corpus Striatum; Dopamine; Dopamine Agents; In Vitro Techniques; Male; Membrane Potentials; Potassium Channels; Rats; Rats, Inbred Strains; Sulpiride | 1988 |
Acetylcholine suppresses calcium current in neurons of Aplysia californica.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Aplysia; Barium; Calcium; Calcium Channels; Cholinesterase Inhibitors; Iontophoresis; Neurons; Potassium; Tetraethylammonium Compounds | 1988 |
An analysis of the inhibitory responses of dopamine and octopamine on Helix central neurons.
Topics: 4-Aminopyridine; Adenylyl Cyclase Inhibitors; Aminopyridines; Animals; Bucladesine; Colforsin; Dopamine; Evoked Potentials; Helix, Snails; Imines; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Octopamine; Potassium Channels | 1988 |
The effect of Lambert-Eaton myasthenic syndrome antibody on slow action potentials in mouse cardiac ventricle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium Channels; Heart; Heart Ventricles; Humans; Immunoglobulin G; In Vitro Techniques; Mice; Neuromuscular Diseases; Reference Values; Syndrome; Tetrodotoxin; Ventricular Function; Verapamil | 1988 |
Transmitter release at mouse motor nerve terminals mediated by temporary accumulation of intracellular barium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Egtazic Acid; In Vitro Techniques; Magnesium; Mice; Motor Endplate; Muscles; Neomycin; Neuromuscular Junction; Neurotransmitter Agents; Ranidae; Tetrodotoxin; Time Factors | 1988 |
Three potassium currents in mouse motor nerve terminals.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Guanidines; Mice; Neuromuscular Junction; Organometallic Compounds; Potassium Channels; Tetraethylammonium Compounds | 1989 |
Effects of nicorandil on the rhythmic contractile response of isolated miniature pig coronary artery to 3,4-diaminopyridine: comparison with nitroglycerin.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Coronary Vasospasm; Coronary Vessels; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Swine; Swine, Miniature | 1986 |
Neurotoxicity of quinolinate in the rat nucleus basalis magnocellularis.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fibers; Kainic Acid; Magnesium; Male; Microinjections; Neural Pathways; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats | 1987 |
Muscarine and luteinizing hormone releasing hormone attenuate adrenaline induced hyperpolarization in amphibian sympathetic ganglia.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electrophysiology; Epinephrine; Ganglia, Sympathetic; Gonadotropin-Releasing Hormone; In Vitro Techniques; Muscarine; Rana catesbeiana | 1985 |
Reversal of paralysis in nerve-muscle preparations isolated from animals with hereditary motor endplate disease.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Mice; Motor Endplate; Neuromuscular Diseases; Neuromuscular Junction; Paralysis | 1985 |
Ion dependence of the release of noradrenaline by tetraethylammonium and 4-aminopyridine from cat splenic slices.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicarbonates; Cations, Divalent; Cats; Guanidine; Guanidines; In Vitro Techniques; Norepinephrine; Perfusion; Spleen; Tetraethylammonium Compounds; Tetrodotoxin | 1985 |
Aminopyridine-sensitivity of spinal cord white matter studied in vitro.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; In Vitro Techniques; Rats; Rats, Inbred Strains; Spinal Cord | 1985 |
Mechanism of alpha 2-adrenergic inhibition of neuroeffector transmission in the mouse vas deferens.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Barium; Calcium; Clonidine; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Norepinephrine; Potassium; Receptors, Adrenergic, alpha; Strontium; Synaptic Transmission; Vas Deferens | 1985 |
4-Aminopyridine leads to restoration of conduction in demyelinated rat sciatic nerve.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Demyelinating Diseases; Female; In Vitro Techniques; Neural Conduction; Paresthesia; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains | 1985 |
The effect of verapamil and EGTA on the rat phrenic nerve-hemidiaphragm preparation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Diaphragm; Egtazic Acid; Electric Stimulation; Ethylene Glycols; In Vitro Techniques; Male; Neostigmine; Neuromuscular Junction; Phrenic Nerve; Rats; Rats, Inbred Strains; Synaptic Transmission; Verapamil | 1985 |
Influence of thyroid hormone levels on the electrical and mechanical properties of rabbit papillary muscle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Body Weight; Electric Stimulation; Electrophysiology; Gallopamil; Heart; Hyperthyroidism; Hypothyroidism; Male; Microscopy, Electron; Organ Size; Papillary Muscles; Rabbits; Thyroxine; Time Factors | 1985 |
Comparison of the action of types A and F botulinum toxin at the rat neuromuscular junction.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Botulinum Toxins; Evoked Potentials; Imidoesters; Injections, Subcutaneous; Lethal Dose 50; Male; Mice; Motor Endplate; Muscle, Smooth; Neuromuscular Junction; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
Baclofen activates voltage-dependent and 4-aminopyridine sensitive K+ conductance in guinea-pig hippocampal pyramidal cells maintained in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Baclofen; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Potassium; Tetraethylammonium Compounds | 1985 |
The effect of 4-aminopyridine-induced increased neuromuscular activity on the metabolism of developing muscles in chick embryos.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Chick Embryo; Creatine Kinase; Energy Metabolism; Isoenzymes; L-Lactate Dehydrogenase; Muscles; Neuromuscular Junction | 1985 |
4-Aminopyridine and haemodialysis in the treatment of verapamil intoxication.
Topics: 4-Aminopyridine; Aged; Aminopyridines; Atropine; Heart Rate; Humans; Male; Renal Dialysis; Time Factors; Verapamil | 1985 |
Neocortical cytopathology in focal aminopyridine seizures as related to the intracortical diffusion of [3H] 4-aminopyridine. Electrophysiologic and light-microscopic studies.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Autoradiography; Blood-Brain Barrier; Capillary Permeability; Cats; Cerebral Cortex; Diffusion; Electroencephalography; Electrophysiology; Histocytochemistry; Immunochemistry; Rats; Rats, Inbred Strains; Seizures; Tritium | 1985 |
Effects of aniline on neuromuscular transmission.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Aniline Compounds; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Neuromuscular Junction; Ranidae; Structure-Activity Relationship; Synaptic Transmission | 1985 |
Potentiating effects of 4-aminopyridine on responses to intramural vagal stimulation in the isolated dog atrium.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dogs; Drug Synergism; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Myocardial Contraction; Parasympathetic Nervous System; Vagus Nerve | 1985 |
[Modulating action of barium and other ions on the sensory activity of frog labyrinth].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Anura; Barium; Calcium; Cobalt; Ear, Inner; Electrophysiology; Potassium; Tetraethylammonium Compounds | 1985 |
Suppression by phenytoin of convulsant-induced afterdischarges at presynaptic nerve terminals.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; In Vitro Techniques; Neuromuscular Junction; Phenytoin; Rana ridibunda; Synaptic Transmission | 1985 |
Improvement in neuromuscular transmission in myasthenia gravis by 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Aged; Amifampridine; Aminopyridines; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electromyography; Humans; Male; Middle Aged; Myasthenia Gravis; Neuromuscular Junction; Pyridostigmine Bromide; Synaptic Transmission | 1985 |
Effects of cholinergic drugs and 4-aminopyridine on cat ciliary muscle contractility.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Carbachol; Cats; Ciliary Body; Muscle Contraction; Parasympathomimetics; Physostigmine; Tetrodotoxin | 1985 |
Spontaneous epileptiform discharges in hippocampal slices induced by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Female; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Seizures | 1985 |
Effects of 4-aminopyridine, GABA and bicuculline on cutaneous receptive fields of cat dorsal horn neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Neurons, Afferent; Sensation; Skin; Spinal Cord; Synaptic Transmission | 1985 |
Effects of 4-aminopyridine on cat blood pressure in relation to the sympathetic nervous system.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Calcium; Cardiovascular Agents; Cats; Female; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Reserpine; Sympathetic Nervous System; Vasoconstriction; Verapamil | 1985 |
Ultracytochemical localization of acetylcholine-like cations in excited motor end-plates by means of ionic fixation.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Cations; Electric Conductivity; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Motor Endplate; Muscles; Neuromuscular Junction; Ranidae; Temperature | 1985 |
Temporal coincidence between synaptic vesicle fusion and quantal secretion of acetylcholine.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Cell Membrane; Freeze Fracturing; Freezing; Microscopy, Electron; Microtomy; Motor Endplate; Rana pipiens; Synaptic Vesicles; Time Factors | 1985 |
Noradrenergic modulation of 4-aminopyridine-induced acetylcholine release from rat cerebral cortex.
Topics: 4-Aminopyridine; Acetylcholine; alpha-Methyltyrosine; Aminopyridines; Animals; Benzylamines; Cerebral Cortex; Fenclonine; Male; Methyltyrosines; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1985 |
Age-related changes of action potential plateau shape in isolated human atrial fibers.
Topics: 4-Aminopyridine; Action Potentials; Adult; Aged; Aging; Aminopyridines; Atrial Function; Caffeine; Heart Atria; Humans; Infant; Middle Aged | 1985 |
[Effect of 4-aminopyridine on the development of experimental botulism].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Botulinum Toxins; Botulism; Male; Mice; Rats | 1985 |
4-Aminopyridine induces expansion of cutaneous receptive fields of dorsal horn cells.
Topics: 4-Aminopyridine; Afferent Pathways; Aminopyridines; Animals; Cats; Female; Foot; Male; Spinal Cord; Time Factors; Touch | 1985 |
Synaptic facilitation by 3-aminopyridine and its antagonism by verapamil and diltiazem.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Benzazepines; Calcium; Diltiazem; Dose-Response Relationship, Drug; Rana catesbeiana; Synapses; Synaptic Transmission; Verapamil | 1985 |
Equipotency of anti-curare activity of 4-aminopyridine and 3,4-diaminopyridine in anesthetized rats.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Anesthesia; Animals; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Sciatic Nerve; Tubocurarine | 1985 |
Long-term potentiation and 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Atropine- and tetrodotoxin-resistant motor activity, responsive to 4-aminopyridine, present in isolated rabbit jejunum.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Drug Resistance; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Synaptic Transmission; Tetrodotoxin | 1985 |
Synergistic interaction of 4-aminopyridine with neostigmine at the neuromuscular junction.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cholinesterase Inhibitors; Drug Synergism; Female; In Vitro Techniques; Magnesium; Motor Endplate; Neostigmine; Neuromuscular Junction; Rats; Rats, Inbred Lew; Tubocurarine | 1985 |
Involvement of local adrenergic receptors in the process of ovulation in gonadotrophin-primed immature rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Corpus Luteum; Female; Gonadotropins, Equine; Isoproterenol; Norepinephrine; Ovulation; Ovulation Induction; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sexual Maturation; Terbutaline | 1985 |
A potent transient outward current regulates excitability of dorsal raphe neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Conductivity; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Influence of calcium and calcium-modulating agents on differentiation of murine erythroleukaemia cells.
Topics: 4-Aminopyridine; Aminopyridines; Amrinone; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Egtazic Acid; Erythrocytes; Erythropoiesis; Friend murine leukemia virus; Gallic Acid; Leukemia, Erythroblastic, Acute; Mice; Razoxane; Verapamil | 1985 |
Different effects of 4-aminopyridine on sensory and motor fibers: pathogenesis of paresthesias.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Motor Activity; Multiple Sclerosis; Nerve Fibers; Paresthesia; Rats; Rats, Inbred Strains; Sensation; Spinal Nerve Roots | 1986 |
Cholinergic modulation of memory in rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arecoline; Brain; Cholinergic Fibers; Male; Memory; Nicotine; Oxotremorine; Physostigmine; Rats; Rats, Inbred Strains; Retention, Psychology | 1985 |
Reversal of xylazine in red deer.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Deer; Drug Combinations; Thiazines; Xylazine; Yohimbine | 1985 |
Effects of 4-aminopyridine (4-AP) on rat neostriatal neurons in an in vitro slice preparation.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Chlorides; Corpus Striatum; In Vitro Techniques; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Rats; Rats, Inbred Strains; Synapses | 1985 |
4-Aminopyridine-induced changes in the electrical and contractile activities of the gastric smooth muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Cats; Electric Conductivity; Female; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Phentolamine; Propranolol; Stomach; Tetrodotoxin | 1985 |
Effect of indapamide on the electromechanical properties of rat myometrium and rat portal vein.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Diuretics; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indapamide; Myometrium; Norepinephrine; Portal Vein; Potassium; Pregnancy; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Uterine Contraction; Vasoconstriction | 1986 |
Dopaminergic control of respiration as shown by effects of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Atropine; Domperidone; Dopamine; Haloperidol; Hemodynamics; Neuromuscular Depolarizing Agents; Phrenic Nerve; Prazosin; Rabbits; Respiration; Salivation; Vagotomy | 1986 |
Acetylcholine synthesis and release by a sympathetic ganglion in the presence of 2-(4-phenylpiperidino) cyclohexanol (AH5183).
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcium; Cats; Electric Stimulation; Female; Ganglia, Sympathetic; Kinetics; Male; Phencyclidine; Physostigmine; Piperidines | 1986 |
Antagonism of xylazine hydrochloride with yohimbine hydrochloride and 4-aminopyridine in captive wapiti.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Artiodactyla; Female; Heart Rate; Immobilization; Male; Respiration; Thiazines; Time Factors; Xylazine; Yohimbine | 1986 |
Release and turnover of noradrenaline in isolated median eminence: lack of negative feedback modulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Electromagnetic Fields; Feedback; Hydroxydopamines; Male; Median Eminence; Norepinephrine; Oxidopamine; Rats; Xylazine; Yohimbine | 1985 |
Control of gap junction formation in canine trachea by arachidonic acid metabolites.
Topics: 4-Aminopyridine; 5,8,11,14-Eicosatetraynoic Acid; Aminopyridines; Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Carbachol; Catechols; Chromones; Dinoprostone; Dogs; Epoprostenol; Female; Indomethacin; Intercellular Junctions; Male; Masoprocol; Microscopy, Electron; Prostaglandins E; Serotonin; Trachea | 1986 |
The effects of 4-aminopyridine on the spinal cord: rhythmic discharges recorded from the peripheral nerves.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Decerebrate State; Electrophysiology; Locomotion; Male; Periodicity; Spinal Cord; Spinal Nerves | 1986 |
Rat hippocampal neurons in culture: Ca2+ and Ca2+-dependent K+ conductances.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cells, Cultured; Hippocampus; Membrane Potentials; Neural Conduction; Neurons; Potassium; Rats | 1986 |
Study of a neuronal potassium current in different culture conditions.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane Permeability; Coturnix; Membrane Potentials; Mesencephalon; Muscles; Neural Crest; Potassium; Quail; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
Inhibition of corticosteroid 11 beta hydroxylation in bovine zona fasciculata cells by the potassium entry blocker 4-aminopyridine.
Topics: 4-Aminopyridine; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aminopyridines; Animals; Cattle; Hydroxylation; In Vitro Techniques; Potassium | 1986 |
Acetylcholine raises excitability by inhibiting the fast transient potassium current in cultured hippocampal neurons.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Atropine; Cells, Cultured; Dose-Response Relationship, Drug; Hippocampus; Neurons; Potassium; Rats; Receptors, Muscarinic | 1986 |
A preclinical evaluation of aminopyridines as putative therapeutic agents in the treatment of botulism.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Botulinum Toxins; Botulism; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Neuromuscular Junction; Paralysis; Rats; Synaptic Transmission; Tetanus Toxin | 1986 |
Treatment of verapamil toxicity in intact dogs.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Blood Pressure; Calcium Chloride; Cardiac Output; Dogs; Dopamine; Epinephrine; Heart Rate; Isoproterenol; Norepinephrine; Phenylephrine; Stimulation, Chemical; Stroke Volume; Verapamil | 1986 |
Noxiustoxin, a short-chain toxin from the Mexican scorpion Centruroides noxius, induces transmitter release by blocking K+ permeability.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Cell Membrane Permeability; Electrophysiology; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Potassium; Scorpion Venoms; Synaptosomes | 1986 |
Depression of spike adaptation and afterhyperpolarization by 4-aminopyridine in hippocampal neurons.
Topics: 4-Aminopyridine; Action Potentials; Adaptation, Physiological; Aminopyridines; Animals; Electric Stimulation; Guinea Pigs; Hippocampus; Membrane Potentials; Neural Inhibition | 1986 |
Extracellular calcium transients and action potential configuration changes related to post-stimulatory potentiation in rabbit atrium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Buffers; Calcium; Diastole; Electric Stimulation; Extracellular Space; Heart; Heart Atria; Male; Myocardial Contraction; Myocardium; Rabbits; Ryanodine; Sodium | 1986 |
Potassium ion channel blockade restores conduction in heat-injured nerve and spinal nerve roots.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Hot Temperature; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; Rats; Spinal Nerve Roots; Sural Nerve; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Effects of 4-aminopyridine on rate-related depression of cardiac action potentials.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Caffeine; Cats; Cesium; Chlorides; Dogs; Female; Heart; Heart Atria; Isoproterenol; Male; Papillary Muscles; Purkinje Fibers; Rats; Rats, Inbred Strains | 1986 |
Action potentials and frequency-dependent secretion in the mouse neurohypophysis.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Arginine Vasopressin; Calcium; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mice; Pituitary Gland, Posterior; Radioimmunoassay | 1986 |
Inhibitory effect of taurine on 4-aminopyridine-stimulated release of labelled dopamine from striatal synaptosomes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glycine; Rats; Rats, Inbred Strains; Synaptosomes; Taurine | 1986 |
Prompt arousal from fentanyl-droperidol-pentobarbital anesthesia in dogs: a preliminary study.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Anesthetics; Animals; Arousal; Dogs; Doxapram; Droperidol; Drug Combinations; Fentanyl; Naloxone; Pentobarbital; Yohimbine | 1986 |
[Toxicity of the combination preparation nivalin-P].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dose-Response Relationship, Drug; Drug Combinations; Galantamine; Lethal Dose 50; Mice; Rats; Time Factors | 1986 |
The effects of hemicholinium-3 (Hc-3) during tetanic (TP) and posttetanic potentiation (PTP) on sympathetic ganglion.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Anura; Calcium; Electric Stimulation; Electrophysiology; Ganglia, Sympathetic; Hemicholinium 3; Muscle Contraction; Synapses; Synaptic Transmission | 1986 |
Transmembrane outward hydrogen current in intracellularly perfused neurones of the snail Helix pomatia.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cadmium; Calcium; Cell Membrane Permeability; Helix, Snails; Hydrogen; Hydrogen-Ion Concentration; Membrane Potentials; Neurons; Potassium; Verapamil | 1986 |
Effects of 4-aminopyridine on the fade response to vagal nerve stimulation in the isolated dog atrium.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dogs; Heart; Heart Atria; Heart Rate; Myocardial Contraction; Vagus Nerve | 1986 |
[Effect 4-aminopyridine on the recovery of segmental reflexes after sectioning of the sciatic nerve in the rat].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Peripheral Nerve Injuries; Rats; Rats, Inbred Strains; Reaction Time; Reflex, Abnormal; Reflex, Monosynaptic; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1986 |
4-Aminopyridine-mediated increase in long-term potentiation in CA1 of the rat hippocampus.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cell Membrane Permeability; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Rats; Rats, Inbred Strains; Synaptic Transmission | 1986 |
Epithelial modulation of tracheal smooth muscle response to antigenic stimulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Antigens; Atropine; Capsaicin; Epithelium; Male; Microscopy, Electron, Scanning; Muscle Contraction; Muscle, Smooth; Ovalbumin; Physostigmine; Rats; Rats, Inbred Strains; Trachea | 1986 |
Increase in the number of presynaptic large intramembrane particles during synaptic transmission at the Torpedo nerve-electroplaque junction.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane; Electric Organ; Electric Stimulation; Endocytosis; Evoked Potentials; Exocytosis; Female; Freeze Fracturing; Intracellular Membranes; Male; Nerve Endings; Reaction Time; Synapses; Synaptic Transmission; Synaptic Vesicles; Torpedo | 1986 |
Mechanisms of tetraethylammonium-induced contraction in the canine coronary artery.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cesium; Chlorides; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Phenylephrine; Potassium; Tetraethylammonium Compounds; Vasodilator Agents; Verapamil | 1986 |
Two types of transient outward currents in adult human atrial cells.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Atrial Function; Electric Conductivity; Heart; Heart Atria; Humans; In Vitro Techniques; Membrane Potentials | 1987 |
Differential effects of Ca antagonists on the noradrenaline release and contraction evoked by nerve stimulation in the presence of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Salicylates; Salicylic Acid; Stereoisomerism; Tetracaine; Tetrodotoxin; Verapamil | 1987 |
A GABAergic depolarizing potential in the hippocampus disclosed by the convulsant 4-aminopyridine.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Bicuculline; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Rats; Receptors, GABA-A | 1987 |
Inhibition of proto-oncogene c-fos transcription by inhibitors of protein kinase C and ion transport.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Amiloride; Aminopyridines; Biological Transport, Active; Calcimycin; Humans; Isoquinolines; Phorbol Esters; Piperazines; Potassium; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; Quinidine; RNA, Messenger; Sodium; Tetraethylammonium Compounds; Transcription, Genetic | 1987 |
Potentiation by 4-aminopyridine of quantal acetylcholine release at the Torpedo nerve-electroplaque junction.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Aminopyridines; Animals; Calcium; Electric Organ; In Vitro Techniques; Magnesium; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Torpedo | 1986 |
Membrane conductance and potassium permeability of the rat lens.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane; Cell Membrane Permeability; Electric Conductivity; In Vitro Techniques; Lens, Crystalline; Membrane Potentials; Potassium; Quinine; Rats; Rats, Inbred Strains; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds | 1987 |
4-Aminopyridine affects synaptosomal protein phosphorylation in rat hippocampal slices.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Calmodulin; Hippocampus; Male; Nerve Tissue Proteins; Phosphorylation; Rats; Rats, Inbred Strains; Synaptosomes | 1987 |
Long-term modifiability of anomalous and delayed rectification in guinea pig inferior olivary neurons.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cations; Electric Conductivity; Guinea Pigs; Harmaline; In Vitro Techniques; Membrane Potentials; Neurons; Olivary Nucleus; Potassium; Tetrodotoxin | 1987 |
[Pharmacologic study of the inhibition of the glomerular input to the olfactory tubercle of the frog induced by a puff of air on the olfactory mucosa].
Topics: 4-Aminopyridine; Aminooxyacetic Acid; Aminopyridines; Animals; beta-Alanine; Bicuculline; gamma-Aminobutyric Acid; Male; Neuroglia; Olfactory Bulb; Olfactory Mucosa; Physical Stimulation; Rana temporaria; Synaptic Transmission | 1987 |
A comparison of the pharmacological actions of 4-aminopyridine and two of its derivatives in the monkey.
Topics: 4-Aminopyridine; Aminopyridines; Anesthetics; Animals; Diazepam; Female; Heart Rate; Ketamine; Macaca nemestrina; Male; Neuromuscular Depolarizing Agents | 1987 |
Antagonism of ethanol-induced depressant effects by 4-aminopyridine in the central nervous system of the rat.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Depression, Chemical; Electric Stimulation; Ethanol; Hippocampus; In Vitro Techniques; Male; Motor Activity; Rats; Rats, Inbred Strains | 1987 |
4-Aminopyridine produces epileptiform activity in hippocampus and enhances synaptic excitation and inhibition.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Convulsants; Epilepsy; Evoked Potentials; Hippocampus; Male; Neural Inhibition; Potassium; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1987 |
Effect of mono- and diaminopyridines on release of [3H]norepinephrine from isolated guinea-pig atrium.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Cocaine; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Norepinephrine | 1987 |
[Antagonism of the neuromuscular-blocking effect of polymyxin B by 3,4-diaminopyridine].
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Female; Male; Muscle Contraction; Neuromuscular Blocking Agents; Phrenic Nerve; Polymyxin B; Polymyxins; Rats | 1987 |
Conduction properties of single nerve fibers in developing rat spinal nerve roots.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Evoked Potentials; Nerve Fibers, Myelinated; Neural Conduction; Ranvier's Nodes; Rats; Rats, Inbred Strains; Spinal Nerve Roots | 1987 |
Saphenous has weak ineffective synapses in sciatic territory of rat spinal cord: electrical stimulation of the saphenous or application of drugs reveal these somatotopically inappropriate synapses.
Topics: 4-Aminopyridine; Action Potentials; Afferent Pathways; Aminopyridines; Animals; Denervation; Electric Stimulation; Hindlimb; Peripheral Nerves; Physical Stimulation; Picrotoxin; Rats; Rats, Inbred Strains; Sciatic Nerve; Spinal Cord; Strychnine; Synapses | 1987 |
Decreasing potassium conductance--a possible mechanism of phasic coronary vasospasm.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Coronary Vasospasm; Coronary Vessels; Dogs; Ergonovine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macaca mulatta; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Niacinamide; Nicorandil; Nifedipine; Potassium; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1985 |
[Effects of 3,4-diaminopyridine on the contractions of guinea-pig tracheal smooth muscle induced by histamine and prostaglandin D2].
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Prostaglandin D2; Prostaglandins D; Tetrodotoxin; Trachea | 1988 |
Synthesis of single- and double-13C-labeled cholesterol oleate.
Topics: 4-Aminopyridine; Aminopyridines; Carbon Isotopes; Cholesterol Esters; Chromatography, High Pressure Liquid; Dicyclohexylcarbodiimide; Magnetic Resonance Spectroscopy | 1988 |
Ultrasound driven synthesis of reversed-phase stationary phases for liquid chromatography using 4-dimethyl-aminopyridine as acid-acceptor.
Topics: 4-Aminopyridine; Aminopyridines; Chromatography, High Pressure Liquid; Ultrasonics | 1988 |
The potassium conductance of the resting squid axon and its blockage by clinical concentrations of general anaesthetics.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Anesthetics; Animals; Axons; Decapodiformes; In Vitro Techniques; Membrane Potentials; Potassium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors | 1988 |
Pharmacokinetics and pharmacodynamics of 2,4-diaminopyridine in the cat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Biotransformation; Blood Pressure; Cats; Heart Rate | 1988 |
Presynaptic Na/Ca action potentials in unmyelinated axons of olfactory cortex.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Amygdala; Animals; Axons; Calcium; Calcium Channel Blockers; Cations, Divalent; Cerebral Cortex; Female; Guinea Pigs; In Vitro Techniques; Male; Potassium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1988 |
Effects of adenosine and calcium entry blockers on 3,4-diaminopyridine-induced rhythmic contractions in dog coronary artery.
Topics: 4-Aminopyridine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amifampridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Phenylisopropyladenosine | 1988 |
Cholinergic nerve terminals in the ventrolateral medullary pressor area: pharmacological evidence.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Blood Pressure; Hemicholinium 3; Medulla Oblongata; Microinjections; Nerve Endings; Parasympathetic Nervous System; Pirenzepine; Receptors, Muscarinic; Scopolamine; Sympathetic Nervous System | 1988 |
High-performance liquid chromatographic determination of 2,4-diaminopyridine in plasma and urine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Crystallization; Spectrophotometry, Ultraviolet | 1987 |
Relation between action potential duration and mechanical activity on rat diaphragm fibers. Effects of 3,4-diaminopyridine and tetraethylammonium.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Caffeine; In Vitro Techniques; Muscle Contraction; Potassium; Rats; Rats, Inbred Strains; Respiratory Muscles; Tetraethylammonium Compounds | 1987 |
Ineffectiveness of 3,4-diaminopyridine as a therapy for type C botulism.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Botulism; Mice; Neuromuscular Junction | 1987 |
Effects of extracellular calcium and calcium channel blocker on silver-induced contractures in frog skeletal muscle fibers.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Interactions; Morpholines; Muscle Contraction; Rana catesbeiana; Silver; Solutions; Tetrodotoxin | 1987 |
Aminoglycosides and 3,4-diaminopyridine on neuromuscular block caused by botulinum type A toxin.
Topics: 4-Aminopyridine; Amifampridine; Aminoglycosides; Aminopyridines; Animals; Anti-Bacterial Agents; Botulinum Toxins; Kinetics; Male; Membrane Potentials; Microelectrodes; Motor Endplate; Neuromuscular Junction; Rana temporaria | 1987 |
Pre- and postsynaptic effects of nicotine on the mouse phrenic nerve-diaphragm preparation.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Muscle Contraction; Muscles; Neostigmine; Neuromuscular Junction; Nicotine; Phrenic Nerve; Succinylcholine; Synapses; Tubocurarine | 1987 |
Angiographic and angioscopic observations of the arterial luminal changes induced by vasospasm.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Angiography; Animals; Carotid Artery Diseases; Dogs; Endoscopy; Female; Fiber Optic Technology; Male; Spasm | 1987 |
Effect of 3,4-diaminopyridine on the survival of mice injected with botulinum neurotoxin type A, B, E, or F.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Botulinum Toxins; Botulism; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Serotyping; Time Factors | 1986 |
3,4-Diaminopyridine partially reverses phospholipid breakdown induced by oxygen deprivation of cultured myocardial cells.
Topics: 4-Aminopyridine; Aminopyridines; Anaerobiosis; Animals; Cells, Cultured; Heart; Kinetics; Myocardium; Phospholipids; Rats; Rats, Inbred Strains | 1986 |
A simple spectrophotometric determination of solid supported amino groups.
Topics: 4-Aminopyridine; Amines; Aminopyridines; Dithiothreitol; Indicators and Reagents; Pyridines; Spectrophotometry, Ultraviolet; Succinimides | 1986 |
Spontaneous excitatory postsynaptic currents in crayfish neuromuscular junctions in the absence and presence of serotonin and 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Astacoidea; Electric Stimulation; Evoked Potentials; Neuromuscular Junction; Serotonin; Synapses | 1986 |
Inhibition of 3,4-diaminopyridine-induced coronary oscillation by adenyl compounds.
Topics: 4-Aminopyridine; Adenine Nucleotides; Adenosine; Amifampridine; Aminophylline; Aminopyridines; Animals; Coronary Vessels; Dilazep; Dogs; Drug Interactions; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle, Smooth, Vascular | 1986 |
Single-step, quantitative derivatization of amino, carboxyl, and hydroxyl groups in iodothyronine amino acids with ethanolic pivalic anhydride containing 4-dimethylaminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, High Pressure Liquid; Diiodothyronines; Ethanol; Pentanoic Acids; Thyronines; Thyroxine; Triiodothyronine | 1986 |
Diagnosis and treatment of botulism in lions.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Amoxicillin; Animals; Animals, Zoo; Botulinum Antitoxin; Botulinum Toxins; Botulism; Carnivora; Diagnosis, Differential; Diazepam; Female; Fluid Therapy; Lions; Male; Salmonella Infections, Animal | 1985 |
Subsynaptosomal calcium distribution during hypoxia and 3,4-diaminopyridine treatment.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Centrifugation; Digitonin; Hypoxia, Brain; Male; Membrane Potentials; Mice; Mitochondria; Potassium; Subcellular Fractions; Synaptosomes | 1985 |
Subsynaptosomal distribution of calcium during aging and 3,4-diaminopyridine treatment.
Topics: 4-Aminopyridine; Aging; Amifampridine; Aminopyridines; Animals; Brain; Calcium; Digitonin; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mitochondria; Onium Compounds; Organophosphorus Compounds; Potassium; Synaptosomes | 1985 |
Presynaptic membrane potential and transmitter release at the crayfish neuromuscular junction.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Astacoidea; Calcium; Membrane Potentials; Models, Neurological; Neuromuscular Junction; Synaptic Transmission; Tetrodotoxin | 1984 |
Rapidly activating hydrogen ion currents in perfused neurones of the snail, Lymnaea stagnalis.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cadmium; Electric Conductivity; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Lymnaea; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Tetraethylammonium; Tetraethylammonium Compounds | 1984 |
Voltage-gated potassium channels are required for human T lymphocyte activation.
Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Diltiazem; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-2; Ion Channels; Kinetics; Leucine; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Phytohemagglutinins; Potassium; Protein Biosynthesis; T-Lymphocytes; Thymidine; Verapamil | 1984 |
Slowly inactivating potassium channels induced in Xenopus oocytes by messenger ribonucleic acid from Torpedo brain.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Brain Chemistry; Electric Conductivity; Female; Ion Channels; Membrane Potentials; Oocytes; Potassium; RNA, Messenger; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Torpedo; Xenopus laevis | 1984 |
Evidence for two voltage-dependent calcium currents in the membrane of the ciliate Stylonychia.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Cadmium; Calcium; Cesium; Ciliophora; Cobalt; Ion Channels; Membrane Potentials; Potassium; Tetraethylammonium; Tetraethylammonium Compounds | 1984 |
Antagonism of d-tubocurarine-induced neuromuscular blockade with a mixture of 4-aminopyridine and neostigmine in man.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Blood Pressure; Electromyography; Female; Heart Rate; Humans; Male; Middle Aged; Neostigmine; Neuromuscular Blocking Agents; Preanesthetic Medication; Synaptic Transmission; Time Factors; Tubocurarine | 1984 |
Anomalous response of rabbit papillary muscles to depolarising current: the possible role of the transient outward current. A pharmacological analysis.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Electrophysiology; In Vitro Techniques; Ion Channels; Papillary Muscles; Potassium; Rabbits; Tyramine; Verapamil | 1984 |
Inhibitory effect of adenosine on transmission in sympathetic ganglia.
Topics: 2-Chloroadenosine; 4-Aminopyridine; Action Potentials; Adenosine; Aminopyridines; Animals; Dipyridamole; Electric Stimulation; Female; Ganglia, Sympathetic; In Vitro Techniques; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1984 |
Outward currents in voltage-clamped rat sympathetic neurones.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Ganglia, Sympathetic; In Vitro Techniques; Ion Channels; Membrane Potentials; Microelectrodes; Neurons; Potassium; Rats | 1984 |
Potentiation between neostigmine and 3,4-diaminopyridine in antagonizing the neuromuscular block induced by D-tubocurarine.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Drug Synergism; Female; Male; Mice; Muscle Contraction; Neostigmine; Nerve Block; Synaptic Transmission; Tubocurarine | 1984 |
Effects of 4-aminopyridine on potassium currents in a molluscan neuron.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Central Nervous System Stimulants; Cholinesterase Inhibitors; In Vitro Techniques; Ion Channels; Neural Conduction; Neuromuscular Depolarizing Agents; Pesticides | 1981 |
Cyclic guanosine 3':5'-monophosphate accumulation and 45Ca-uptake by rat superior cervical ganglia during preganglionic stimulation.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Autonomic Fibers, Preganglionic; Bethanechol; Bethanechol Compounds; Calcium; Cyclic GMP; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Ganglia, Sympathetic; In Vitro Techniques; Male; Ouabain; Peptides; Potassium; Rats; Rats, Inbred Strains | 1981 |
Glutamate agonistic and antagonistic activity of L-proline investigated in the hippocampal slice.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hippocampus; Potassium; Proline; Rats; Receptors, Cell Surface; Receptors, Glutamate; Synapses; Synaptic Transmission | 1981 |
[Effect of tetanus toxin on mechanisms by which calcium ions regulate transmitter secretion at the neuromuscular junction].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcimycin; Calcium; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Ouabain; Rats; Tetanus Toxin | 1981 |
Kinetic analysis of the action of chemical modulators on neuromuscular transmission.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; Kinetics; Neuromuscular Junction; Neurotransmitter Agents; Ranidae; Streptomycin; Synaptic Transmission | 1981 |
Ways to discern the presynaptic effect of drugs on neurotransmitter release.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cations, Divalent; Diamide; Kinetics; Mathematics; Models, Neurological; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Synapses | 1982 |
Antagonism of xylazine sedation in dogs by 4-aminopyridine and yohimbine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cats; Central Nervous System Stimulants; Dogs; Drug Combinations; Female; Heart Rate; Male; Neuromuscular Depolarizing Agents; Respiration; Thiazines; Xylazine; Yohimbine | 1982 |
Reversal of the neuroleptanalgesic effect of droperidolfentanyl in the dog by 4-aminopyridine and naloxone.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cardiovascular Agents; Central Nervous System Stimulants; Dogs; Droperidol; Drug Combinations; Drug Therapy, Combination; Female; Fentanyl; Heart Rate; Male; Naloxone; Respiration; Yohimbine | 1982 |
The regulation of cyclic nucleotides in a sympathetic ganglion.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Autonomic Fibers, Preganglionic; Calcium; Cyclic AMP; Cyclic GMP; Electric Stimulation; Ganglia, Sympathetic; Male; Membrane Potentials; Neurotransmitter Agents; Phosphatidylinositols; Potassium; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1982 |
Effects of tetraethylammonium and 4-aminopyridine on the somatic potentials of an identified molluscan neuron.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Extracellular Space; Intracellular Fluid; Iontophoresis; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Snails; Tetraethylammonium; Tetraethylammonium Compounds | 1982 |
Facilitatory effects of 4-aminopyridine on strontium-mediated evoked and delayed transmitter release from motor nerve terminals.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Anura; Electric Stimulation; In Vitro Techniques; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Rana esculenta; Strontium; Tetrodotoxin | 1982 |
Effect of 4-aminopyridine on transmitter release in synaptosomes.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Brain; Calcium; Culture Techniques; gamma-Aminobutyric Acid; Mice; Neurotransmitter Agents; Potassium; Stimulation, Chemical; Synaptic Transmission; Synaptosomes | 1982 |
Antagonism of xylazine sedation by 4-aminopyridine and yohimbine in cattle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cardiovascular Agents; Cattle; Central Nervous System Stimulants; Heart Rate; Male; Neuromuscular Depolarizing Agents; Respiration; Thiazines; Xylazine; Yohimbine | 1982 |
Complete immobility produced in dogs by xylazine-atropine: antagonism by 4-aminopyridine and yohimbine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arousal; Atropine; Cardiovascular Agents; Central Nervous System Stimulants; Dogs; Female; Heart Rate; Male; Reflex; Respiration; Thiazines; Xylazine; Yohimbine | 1982 |
Antagonism of ketamine anesthesia in cats by 4-aminopyridine and yohimbine.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, General; Animals; Arousal; Blood Pressure; Cats; Central Nervous System Stimulants; Electrocardiography; Electroencephalography; Electromyography; Female; Ketamine; Male; Reflex; Respiration; Yohimbine | 1983 |
Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arecoline; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Drug Interactions; Hexamethonium; Hexamethonium Compounds; Hypoxia; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Parasympathomimetics; Physostigmine; Structure-Activity Relationship | 1983 |
Action potential in neurons of motor nerve net of Cyanea (Coelenterata).
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cations, Divalent; Cnidaria; Motor Neurons; Nerve Net; Nervous System Physiological Phenomena; Refractory Period, Electrophysiological; Scyphozoa; Tetraethylammonium Compounds; Tetrodotoxin | 1983 |
Effects of 4-aminopyridine and 3,4-diaminopyridine on transmitter release at the neuromuscular junction.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Evoked Potentials; Female; Ion Channels; Microelectrodes; Motor Endplate; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Stimulation, Chemical; Synaptic Transmission | 1983 |
Characteristics of inhibitory post-synaptic currents in brain-stem neurones of the lamprey.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Brain Stem; Calcium; Fishes; Glycine; In Vitro Techniques; Lampreys; Membrane Potentials; Neurons; Neurotransmitter Agents; Potassium; Receptors, Neurotransmitter; Tetrodotoxin | 1983 |
Caution of use of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Central Nervous System Stimulants; Drug Utilization; Humans | 1983 |
Different effects of types A and B botulinum toxin on transmitter release at the rat neuromuscular junction.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Botulinum Toxins; Dinitrophenols; Electric Stimulation; Evoked Potentials; Male; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission | 1983 |
Presynaptic neurotransmitter and chemosensory responses to natural stimuli.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Carbon Dioxide; Carotid Body; Cats; Chemoreceptor Cells; Female; Hypercapnia; Hypoxia; Injections, Intra-Arterial; Injections, Intravenous; Neurotransmitter Agents; Oxygen; Partial Pressure; Respiration; Synapses | 1984 |
[Antagonism of 4-aminopyridine on the central nervous system depressant effects of scopolamine in rabbits].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Central Nervous System Depressants; Central Nervous System Stimulants; Electroencephalography; Female; Male; Physostigmine; Rabbits; Scopolamine | 1984 |
Actions of 4-aminopyridine on mammalian ganglion cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Membrane Potentials; Rabbits; Synaptic Transmission; Tubocurarine | 1984 |
Muscarinic receptors and [3H]inositol incorporation in a rat sympathetic ganglion.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Bethanechol; Bethanechol Compounds; Cyclic GMP; Ganglia, Sympathetic; Hexamethonium; Hexamethonium Compounds; Inositol; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tetrodotoxin; Tritium | 1984 |
Comparison of some pharmacological properties of 4-aminopyridine and 3,4-diaminopyridine in vivo.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Central Nervous System Stimulants; Depression, Chemical; Drug Interactions; Mice; Morphine; Respiration | 1984 |
Comparison of five preanesthetic medicaments in thiopental-anesthetized cats: antagonism by selected compounds.
Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Anesthesia, General; Animals; Arousal; Benzodiazepinones; Cats; Central Nervous System Stimulants; Convulsants; Diazepam; Drug Antagonism; Female; Flumazenil; Ketamine; Male; Meperidine; Naloxone; Pentobarbital; Preanesthetic Medication; Sodium Chloride; Xylazine; Yohimbine | 1984 |
Effects of 4-aminopyridine on the non-adrenergic inhibitory neurotransmission in the guinea-pig duodenum.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Central Nervous System Stimulants; Duodenum; Egtazic Acid; Evoked Potentials; Female; Guinea Pigs; Male; Membrane Potentials; Muscle, Smooth; Neural Inhibition; Synaptic Transmission; Tetraethylammonium Compounds; Verapamil | 1984 |
Substance P, bethanechol, 4-aminopyridine, and potassium antagonize the depressing effects of low-frequency stimulation, tetrodotoxin, procaine, and of magnesium on the field-stimulated guinea-pig vas deferens.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bethanechol Compounds; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Muscle Contraction; Muscle, Smooth; Potassium; Procaine; Substance P; Tetrodotoxin; Vas Deferens | 1980 |
Antagonism of the ruthenium red-induced paralysis in mice by 4-aminopyridine, guanidine and lanthanum.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Guanidine; Guanidines; Lanthanum; Mice; Muscle Hypotonia; Neuromuscular Junction; Paralysis; Ruthenium; Ruthenium Red | 1982 |
The actions of 3,4-diaminopyridine in bullfrog sympathetic ganglia.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Axonal Transport; Ganglia, Sympathetic; Microelectrodes; Rana catesbeiana; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tubocurarine | 1982 |
Effects of 4-aminopyridine and tetraethylammonium on relaxant responses of isolated dog coronary arteries to 2-nicotinamidoethyl nitrate (SG-75).
Topics: 4-Aminopyridine; Aminopyridines; Animals; Coronary Vessels; Dinoprost; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Nitrates; Potassium; Prostaglandins F; Tetraethylammonium Compounds; Vasoconstriction | 1982 |
Lack of effect of 4-aminopyridine on choreic movements.
Topics: 4-Aminopyridine; Aminopyridines; Humans; Huntington Disease; Middle Aged | 1982 |
[Properties of membrane ionic currents in pituitary clone cells].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Line; Clone Cells; Cobalt; Electrophysiology; Pituitary Neoplasms; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1983 |
Comparative study of the effects of 4-aminopyridine and tetraethylammonium on neuro-effector transmission in the guinea-pig vas deferens.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Neuroeffector Junction; Sympathetic Nervous System; Synaptic Transmission; Tetraethylammonium Compounds; Time Factors; Vas Deferens | 1980 |
Effects of 4-aminopyridine on depolarization induced automaticity in ventricular myocardium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Ferrets; Guinea Pigs; In Vitro Techniques; Ion Channels; Myocardial Contraction; Papillary Muscles; Potassium | 1980 |
Poisoning with 4-aminopyridine: report of three cases.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Animals; Chromatography; Humans; Ion Channels; Male; Potassium | 1980 |
Functional antagonism by calcium of an intrinsic opioid mechanism in the guinea-pig isolated ileum.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Peristalsis; Receptors, Opioid | 1980 |
Effect of 3,4-diaminopyridine and tetraethylammonium on the presynaptic blockade caused by beta-bungarotoxin.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Bungarotoxins; Chickens; In Vitro Techniques; Mice; Neuromuscular Junction; Synapses; Synaptic Transmission; Tetraethylammonium Compounds | 1980 |
Increase of cGMP and accumulation of 45Ca2+ evoked by drugs acting on sodium or potassium channels.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cerebellum; Cyclic GMP; In Vitro Techniques; Ion Channels; Mice; Potassium; Scorpion Venoms; Sodium; Tetrodotoxin | 1981 |
Studies on the role of Na+, K+ and Cl- ion permeabilities in K+-induced release of 3H-noradrenaline from rat brain slices and synaptosomes and in its presynaptic alpha-adrenergic modulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Chlorides; Electrolytes; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium; Synaptosomes; Tetrodotoxin | 1981 |
Action potential electrogenesis in mammalian central axons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Cats; Cerebellum; Differential Threshold; Ion Channels; Mammals; Nerve Fibers; Nerve Fibers, Myelinated; Potassium; Rats; Refractory Period, Electrophysiological; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds | 1981 |
Membrane potential changes of mouse adrenal zona fasciculata cells in response to adrenocorticotropin and adenosine 3',5'-monophosphate.
Topics: 4-Aminopyridine; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminopyridines; Animals; Cobalt; Cyclic AMP; Ion Channels; Male; Membrane Potentials; Mice; Tetrodotoxin | 1982 |
Potentiation of bovine growth hormone release by an inhibitor of potassium channels.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Cattle; Drug Synergism; Growth Hormone; In Vitro Techniques; Ion Channels; Physostigmine; Pituitary Gland; Potassium | 1981 |
Modifications to synaptic transmission at group Ia synapses on cat spinal motoneurones by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Evoked Potentials; Motor Neurons; Neurons, Afferent; Spinal Cord; Synapses; Synaptic Transmission | 1981 |
Effects of 4-aminopyridine on synaptic transmission in the cat spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Cats; Cerebellum; Dose-Response Relationship, Drug; Motor Neurons; Neural Inhibition; Neuromuscular Depolarizing Agents; Neurons, Afferent; Spinal Cord; Synapses; Synaptic Transmission; Time Factors | 1982 |
Presynaptic alpha-adrenoceptors and opiate receptors: inhibition of [3H]noradrenaline release from rat cerebral cortex slices by different mechanisms.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Male; Morphine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid | 1982 |
Potassium currents in the giant axon of the crab Carcinus maenas.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Axons; Brachyura; Cesium; Electric Conductivity; Ion Channels; Kinetics; Membrane Potentials; Potassium; Quaternary Ammonium Compounds; Sodium | 1982 |
3,4-diaminopyridine alters acetylcholine metabolism and behavior during hypoxia.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Animals; Behavior, Animal; Brain; Calcium; Glucose; Homeostasis; Hypoxia; Ion Channels; Male; Mice; Oxygen; Potassium | 1982 |
Acetylcholine changes underlying transmission of a single nerve impulse in the presence of 4-aminopyridine in Torpedo.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aminopyridines; Animals; Cytoplasm; Electric Organ; Female; Freezing; In Vitro Techniques; Male; Membrane Potentials; Synaptic Transmission; Synaptic Vesicles; Temperature; Torpedo | 1982 |
Enhancement of synaptic transmission by 4-aminopyridine in hippocampal slices of the rat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dendrites; Hippocampus; In Vitro Techniques; Intracellular Fluid; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Rats; Synapses; Synaptic Transmission; Tetrodotoxin | 1982 |
Treating monocularly deprived lambs with 4-aminopyridine produces rapid changes in ocular dominance only after short periods of deprivation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dominance, Cerebral; Sensory Deprivation; Sheep; Synaptic Transmission; Time Factors; Visual Cortex; Visual Perception | 1982 |
Aminopyridine block of transient potassium current.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Electric Conductivity; In Vitro Techniques; Ion Channels; Membrane Potentials; Microelectrodes; Mollusca; Neural Inhibition; Neurons; Potassium | 1982 |
Regulation of cyclic AMP accumulation in a rat sympathetic ganglion: effects of vasoactive intestinal polypeptide.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cyclic AMP; Electric Stimulation; Ganglia, Sympathetic; Gastrointestinal Hormones; Male; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1982 |
Exposure to 4-aminopyridine prevents depressant effects of opiates on sensory-evoked dorsal-horn network responses in spinal cord cultures.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Ganglia, Spinal; Mice; Narcotic Antagonists; Narcotics; Neuromuscular Depolarizing Agents; Organ Culture Techniques; Receptors, Opioid; Spinal Cord | 1982 |
Multiple action of acetylcholine at a muscarinic receptor studied in the rat hippocampal slice.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Atropine; Cholinesterase Inhibitors; Cyclic GMP; Hippocampus; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Tubocurarine | 1982 |
Electronic properties of motor nerve terminals.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Evoked Potentials; Membrane Potentials; Motor Endplate; Motor Neurons; Neuromuscular Junction; Rana temporaria; Synaptic Transmission; Tetraethylammonium Compounds; Tetrodotoxin | 1982 |
A comparison of 3,4-diaminopyridine and 4-aminopyridine in the anaesthetized cat.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Anesthesia; Animals; Blood Pressure; Cats; Female; Heart Rate; Male; Neuromuscular Junction; Nictitating Membrane; Synaptic Transmission | 1982 |
Effect of 4-aminopyridine on neurotransmission in smooth muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Synaptic Transmission | 1982 |
Effects of dithiothreitol, 5,5'-dithiobis(2-nitrobenzoic acid) and N-ethylmaleimide on synaptic transmission at sympathetic ganglion cells of frog.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; Ganglia, Sympathetic; In Vitro Techniques; Microelectrodes; Nitrobenzoates; Rana catesbeiana; Synaptic Transmission | 1982 |
Resting potential of the mouse neuroblastoma cells. I. The presence of K+ channels activated at high K+ concentration but closed at low K+ concentration including the physiological concentration.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Line; Electrophysiology; Ion Channels; Membrane Potentials; Mice; Neuroblastoma; Potassium; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds | 1983 |
Effect of different convulsant drugs on some seizure parameters in morphine-dependent mice.
Topics: 3-Mercaptopropionic Acid; 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Brain; Convulsants; Humans; Mice; Morphine Dependence; Pentylenetetrazole; Receptors, Opioid; Seizures; Strychnine | 1983 |
Facilitatory effect of some drugs on transmission in the frog sympathetic ganglion.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Dimethyl Sulfoxide; Evoked Potentials; Ganglia, Sympathetic; In Vitro Techniques; Rana esculenta; Rana temporaria; Stimulation, Chemical; Synaptic Membranes; Synaptic Transmission | 1982 |
Mechanism of plateau loss in rabbit papillary muscle after a short rest. Role of outward current.
Topics: 4-Aminopyridine; Adenylyl Cyclases; Aminopyridines; Animals; Calcium; Cell Membrane Permeability; Cesium; Cyclic AMP; Electric Stimulation; Electrocardiography; Guinea Pigs; Ion Channels; Myocardial Contraction; Myocardium; Papillary Muscles; Potassium; Rabbits; Sodium; Tetraethylammonium Compounds | 1982 |
Drugs affecting the calcium-dependent slow depolarization mechanism of the cardiac cell membrane.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Catecholamines; Cats; Electrocardiography; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Ion Channels; Male; Myocardial Contraction; Prostaglandins; Serotonin; Sodium; Tetrodotoxin; Tissue Extracts | 1982 |
Effects of 3,4-diaminopyridine on mechanical and electrical responses of frog single muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscles; Potassium; Rana temporaria; Tubocurarine | 1983 |
Differential control of Ca2+-dependent [3H]noradrenaline release from rat brain slices through presynaptic opiate receptors and alpha-adrenoceptors.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Cadmium; Calcium; Cell Membrane Permeability; Electric Stimulation; Electrolytes; In Vitro Techniques; Male; Morphine; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Tritium | 1983 |
Protein phosphorylation/dephosphorylation and the transient, voltage-dependent potassium conductance in Hermissenda crassicornis.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Ion Channels; Membrane Proteins; Molecular Weight; Mollusca; Phosphoproteins; Phosphorylation; Potassium | 1983 |
Site of action and active form of aminopyridines in squid axon membranes.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Axons; Calcium Channel Blockers; Decapodiformes; Electrophysiology; Ion Channels; Potassium; Structure-Activity Relationship | 1983 |
Calcium action potentials in rat fast-twitch and slow-twitch muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Barium; Calcium; Chlorides; Electric Conductivity; In Vitro Techniques; Ion Channels; Muscles; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Time Factors | 1983 |
Kinetic properties of calcium channels of twitch muscle fibres of the frog.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Muscles; Potassium; Rana temporaria; Tetraethylammonium; Tetraethylammonium Compounds | 1983 |
Novel drug of choice in Eaton-Lambert syndrome.
Topics: 4-Aminopyridine; Aged; Amifampridine; Aminopyridines; Female; Humans; Middle Aged; Myasthenia Gravis; Neuromuscular Junction; Synaptic Transmission | 1983 |
Maturation of mammalian myelinated fibers: changes in action-potential characteristics following 4-aminopyridine application.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Ion Channels; Male; Nerve Fibers, Myelinated; Peripheral Nerves; Potassium; Rats; Rats, Inbred Strains; Refractory Period, Electrophysiological | 1983 |
Synaptic transmission in low extracellular calcium is preserved by 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; Extracellular Space; Ganglia, Sympathetic; In Vitro Techniques; Rana catesbeiana; Receptors, Neurotransmitter; Synapses | 1983 |
Mechanism of negative feed-back inhibition of norepinephrine release by alpha-adrenergic agonists.
Topics: 4-Aminopyridine; Adrenergic Fibers; Aminopyridines; Animals; Calcium; Electric Stimulation; Epinephrine; Feedback; Guinea Pigs; Heart; Male; Neural Inhibition; Norepinephrine; Receptors, Adrenergic; Tetraethylammonium Compounds | 1983 |
Kinetics of the TEA and 4-AP sensitive K+ current in the slowly adapting lobster stretch receptor neurone.
Topics: 4-Aminopyridine; Adaptation, Physiological; Aminopyridines; Animals; Ion Channels; Kinetics; Mechanoreceptors; Models, Biological; Nephropidae; Neurons; Potassium; Tetraethylammonium Compounds | 1983 |
Peripheral control of the cat's step cycle. II. Entrainment of the central pattern generators for locomotion by sinusoidal hip movements during "fictive locomotion.".
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Curare; Denervation; Hindlimb; Hip Joint; Levodopa; Locomotion; Movement; Neuromuscular Junction; Peripheral Nerves; Spinal Nerves; Synaptic Transmission | 1983 |
Intracellular ion control in lobster stretch receptor neurone.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Membrane Permeability; gamma-Aminobutyric Acid; Intracellular Fluid; Ion Channels; Ion Exchange; Mechanoreceptors; Models, Biological; Nephropidae; Neurons; Potassium; Sodium; Tetraethylammonium Compounds; Tetrodotoxin | 1983 |
Potassium channels moderate ectopic excitability of nerve-end neuromas in rats.
Topics: 4-Aminopyridine; Afferent Pathways; Aminopyridines; Animals; Axons; Evoked Potentials; Ion Channels; Male; Muridae; Nerve Regeneration; Neuroma; Potassium; Sciatic Nerve; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Tibial Nerve | 1983 |
Computer simulation for studying calcium dependent abnormalities in firing mechanism of molluscan neurones.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cell Membrane; Computers; Electrophysiology; In Vitro Techniques; Ion Channels; Models, Biological; Mollusca; Neurons; Potassium; Software | 1982 |
Influence of Ca2+ on the mechanosensitivity of the hair cells in the lateral line organs of Necturus maculosus.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cations, Monovalent; Cell Membrane Permeability; Gallopamil; Hair Cells, Auditory; Ion Channels; Mechanoreceptors; Necturus maculosus; Physical Stimulation; Potassium Chloride; Vibration | 1983 |
[Predominant blocking of fast potassium current channels in mollusk neurons by 4-aminopyridine].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dose-Response Relationship, Drug; Ganglia; In Vitro Techniques; Ion Channels; Kinetics; Lymnaea; Potassium | 1983 |
Effects of 4-aminopyridine and tetraethylammonium chloride on the electrical activity and cable properties of canine tracheal smooth muscle.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Atropine; Binding Sites; Dogs; Female; Gallopamil; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Microelectrodes; Muscle, Smooth; Potassium; Receptors, Muscarinic; Tetraethylammonium Compounds; Time Factors; Trachea | 1983 |
Synaptic facilitatory and depressant actions of 3,4-diaminopyridine: correlation with anticurare properties.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Curare; Dose-Response Relationship, Drug; Female; Ganglia, Sympathetic; In Vitro Techniques; Male; Rana catesbeiana; Synapses; Synaptic Transmission; Tubocurarine | 1983 |
Calcium-dependent 4-aminopyridine stimulation of protein phosphorylation in squid optic lobe synaptosomes.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Calcium; Decapodiformes; Electrophoresis, Polyacrylamide Gel; Ethanolamines; Ion Channels; Membrane Proteins; Microscopy, Electron; Nerve Tissue Proteins; Optic Lobe, Nonmammalian; Phosphorylation; Synaptosomes | 1983 |
Actions of potassium channel blockers on guinea-pig lateral olfactory tract axons.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Axons; Barium; Central Nervous System; Cesium; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Olfactory Pathways; Potassium; Sparteine; Synapses | 1984 |
Frequency dependent intermittency and ionic basis of impulse conduction in postganglionic sympathetic fibres of guinea-pig vas deferens.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Autonomic Fibers, Postganglionic; Calcium; Ganglia, Sympathetic; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Ion Channels; Male; Neural Conduction; Potassium; Sodium; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens | 1984 |
Presynaptic currents in frog motor endings.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Electric Conductivity; Ion Channels; Motor Neurons; Nerve Endings; Rana esculenta; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1984 |
The inhibitory action of PGF2 alpha on release of [3H]noradrenaline enhanced by alpha 2-adrenoceptor blockade, sodium-pump inhibition and 4-aminopyridine in the main pulmonary artery of the rabbit.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dinoprost; Electric Stimulation; Female; Ion Channels; Male; Norepinephrine; Potassium; Prostaglandins F; Pulmonary Artery; Rabbits; Receptors, Adrenergic, alpha; Sodium; Yohimbine | 1984 |
Capsaicin blocks synaptically activated potassium conductance in snail neurone.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Capsaicin; Electric Conductivity; Helix, Snails; Ion Channels; Neurons; Potassium; Quinine; Synapses; Synaptic Transmission | 1984 |
The action of thallium acetate on neuromuscular transmission in the rat phrenic nerve-diaphragm preparation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Diaphragm; Female; Guanidine; Guanidines; Kinetics; Male; Muscle Contraction; Neuromuscular Junction; Organometallic Compounds; Paralysis; Phrenic Nerve; Potassium; Rats; Synaptic Transmission; Thallium | 1984 |
Rat hippocampal neurons in culture: potassium conductances.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Electrophysiology; Hippocampus; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1984 |
2,4-Diamino-5-cyano-6-halopyridines: a new class of cyclic AMP phosphodiesterase inhibitors with therapeutic potential.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-Aminopyridine; Aminopyridines; Animals; Bronchodilator Agents; Glucose; Insulin; Insulin Secretion; Kinetics; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains | 1984 |
Contractile effects of 4-aminopyridine on isolated frog rectus abdominis muscles.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Neuromuscular Depolarizing Agents; Potassium Chloride; Rana temporaria; Tubocurarine | 1984 |
Ionic currents of solitary horizontal cells isolated from goldfish retina.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Calcium; Cells, Cultured; Cyprinidae; Egtazic Acid; Goldfish; Interneurons; Membrane Potentials; Potassium; Retina; Tetraethylammonium Compounds | 1983 |
Automaticity of ventricular fibers induced by low concentrations of barium.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Barium; Cesium; Dogs; Dose-Response Relationship, Drug; Gallopamil; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Lanthanum; Manganese; Osmolar Concentration; Permeability; Propranolol; Purkinje Fibers; Tetraethylammonium; Tetraethylammonium Compounds | 1984 |
[Rohypnol poisoning as a cause of postanesthetic coma and the success of 4-aminopyridine therapy].
Topics: 4-Aminopyridine; Adult; Aminopyridines; Anesthesia; Coma; Female; Flunitrazepam; Humans; Naloxone; Physostigmine; Postoperative Complications | 1984 |
Effect of 4-aminopyridine on gastric secretion in rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Gastric Mucosa; Histamine; Rats | 1984 |
Histamine-induced rhythmic contraction of hog carotid artery smooth muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Carotid Arteries; Electrophysiology; Female; Histamine; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Ouabain; Potassium; Receptors, Histamine H1; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1984 |
High-performance liquid chromatographic determination of 3,4-diaminopyridine in human plasma.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Chromatography, High Pressure Liquid; Humans | 1984 |
Effects of veratridine, tetrodotoxin and other drugs that alter electrical behaviour on secretion of melanocyte-stimulating hormone from melanotrophs of the pituitary pars intermedia.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium Channel Blockers; Cells, Cultured; Drug Interactions; Female; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred Strains; Pituitary Gland, Anterior; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine; Veratrine | 1984 |
Effects of 4-aminopyridine on sympathetic preganglionic neuron activity.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Sympathetic; Neurons; Phrenic Nerve; Reflex; Reflex, Monosynaptic; Respiration; Sympathetic Nervous System | 1984 |
Effects of 4-aminopyridine on the field potentials of hippocampal slices.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cobalt; Dendrites; Evoked Potentials; Hippocampus; In Vitro Techniques; Nickel; Rats; Sodium | 1984 |
The effects of aminopyridines on the cortical evoked potentials.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Cats; Cerebral Cortex; Evoked Potentials, Somatosensory; Female; Male; Seizures | 1984 |
Inhibitory modulation of cat somatosensory cortex: a pharmacological study.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cats; Evoked Potentials; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; Neural Inhibition; Picrotoxin; Somatosensory Cortex; Taurine | 1984 |
Antagonism of xylazine sedation in steers by doxapram and 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, General; Animals; Cardiovascular Agents; Cattle; Doxapram; Drug Combinations; Male; Thiazines; Xylazine; Yohimbine | 1984 |
Reversal of pentobarbital anesthesia with 4-aminopyridine and yohimbine in cats pretreated with acepromazine and xylazine.
Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Anesthesia, General; Animals; Arousal; Cardiovascular Agents; Cats; Female; Heart Rate; Male; Pentobarbital; Preanesthetic Medication; Respiration; Thiazines; Xylazine; Yohimbine | 1984 |
Pharmacokinetics of 4-aminopyridine in cattle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cattle; Computers; Half-Life; Injections, Intravenous; Kinetics; Male; Neuromuscular Depolarizing Agents | 1984 |
Meperidine-acepromazine-pentobarbital anesthesia in cats: reversal by 4-aminopyridine and yohimbine.
Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Anesthesia, General; Animals; Arousal; Cats; Drug Combinations; Female; Heart Rate; Male; Meperidine; Neuromuscular Depolarizing Agents; Pentobarbital; Preanesthetic Medication; Respiration; Yohimbine | 1984 |
Effective treatment of verapamil intoxication with 4-aminopyridine in the cat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Antidotes; Blood Pressure; Cats; Heart Rate; Humans; Substance Withdrawal Syndrome; Verapamil | 1984 |
Treatment of Lambert-Eaton syndrome: 3,4-diaminopyridine and pyridostigmine.
Topics: 4-Aminopyridine; Aged; Amifampridine; Aminopyridines; Autoimmune Diseases; Female; Humans; Middle Aged; Myasthenia Gravis; Pyridostigmine Bromide; Syndrome | 1984 |
Application of N,N-dimethylformamide dineopentyl acetal for efficient anchoring of N alpha-9-fluorenylmethyloxycarbonylamino acids as p-alkoxybenzyl esters in solid-phase peptide synthesis.
Topics: 4-Aminopyridine; Acetals; Amino Acids; Aminopyridines; Benzyl Alcohols; Chemical Phenomena; Chemistry; Dicyclohexylcarbodiimide; Fluorenes; Peptides | 1984 |
Angiotensin is not required for hypoxic constriction in salt solution-perfused rat lungs.
Topics: 4-Aminopyridine; Aminopyridines; Analysis of Variance; Angiotensin II; Animals; Hypoxia; Male; Perfusion; Potassium Chloride; Pulmonary Circulation; Rats; Rats, Inbred Strains; Sodium Chloride; Vanadates; Vanadium; Vasoconstriction | 1984 |
The influence of dantrolene, diazepam, pentobarbital and 4-aminopyridine on shortening induced depression in isolated muscle fibres of the frog.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Dantrolene; Diazepam; Muscle Contraction; Muscles; Pentobarbital; Rana temporaria | 1983 |
Aging and 3,4-diaminopyridine alter synaptosomal calcium uptake.
Topics: 4-Aminopyridine; Aging; Aminopyridines; Animals; Biological Transport, Active; Brain; Calcium; Kinetics; Potassium; Rats; Rats, Inbred F344; Synaptosomes | 1983 |
Electrical responses of smooth muscle cells of the mouse uterus to adenosine triphosphate.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Aminopyridines; Animals; Apamin; Dose-Response Relationship, Drug; Evoked Potentials; Female; In Vitro Techniques; Membrane Potentials; Mice; Muscle, Smooth; Pregnancy; Procaine; Tetraethylammonium; Tetraethylammonium Compounds; Uterus | 1983 |
Improvement of 8-arm maze performance in aged Fischer 344 rats with 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Aging; Amifampridine; Aminopyridines; Animals; Male; Memory, Short-Term; Rats | 1983 |
Transient outward current and rate dependence of action potential duration in rabbit cardiac ventricular muscle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Electric Stimulation; Electrophysiology; Guinea Pigs; In Vitro Techniques; Papillary Muscles; Rabbits; Strontium | 1983 |
Acepromazine-xylazine combination in dogs: antagonism with 4-aminopyridine and yohimbine.
Topics: 4-Aminopyridine; Acepromazine; Aminopyridines; Animals; Blood Pressure; Dogs; Female; Immobilization; Male; Neuromuscular Depolarizing Agents; Respiration; Thiazines; Xylazine; Yohimbine | 1983 |
The role of a noradrenergic system in the antinociceptive effects of 4-aminopyridine in the rat.
Topics: 4-Aminopyridine; Aminopyridines; Analgesics; Animals; Cholinesterase Inhibitors; Male; Norepinephrine; Physostigmine; Rats; Rats, Inbred Strains | 1983 |
Effects of 4-aminopyridine on calcium action potentials and calcium current under voltage clamp in spinal neurons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Fetus; Mice; Neuromuscular Depolarizing Agents; Neurons; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1983 |
An ultrastructural study of presynaptic membrane specializations in sympathetic ganglia of 4-aminopyridine treated guinea pigs and rats.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Female; Freeze Fracturing; Ganglia, Sympathetic; Guinea Pigs; Male; Microscopy, Electron; Rats; Synapses; Synaptic Membranes | 1983 |
The effect of some new aminopyridines on mammalian non-myelinated nerve fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Biological Transport, Active; Guinea Pigs; In Vitro Techniques; Nerve Fibers; Sodium; Vagus Nerve | 1983 |
Comparison of five preanesthetic medicaments in pentobarbital-anesthetized dogs: antagonism by 4-aminopyridine, yohimbine, and naloxone.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, General; Animals; Dogs; Drug Combinations; Female; Heart Rate; Male; Naloxone; Neuromuscular Depolarizing Agents; Pentobarbital; Preanesthetic Medication; Respiration; Yohimbine | 1983 |
Hemodynamic effects of high dosages of verapamil and the lack of protection by 4-aminopyridine in the rabbit.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cardiovascular Agents; Female; Heart Rate; Hemodynamics; Levulinic Acids; Male; Rabbits; Verapamil | 1983 |
[Antagonistic effects of neostigmine, 4-aminopyridine and 3,4-diaminopyridine on muscle relaxing effects of d-tubocurarine].
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Muscle Contraction; Muscle Relaxation; Neostigmine; Neuromuscular Depolarizing Agents; Rats; Tubocurarine | 1983 |
Synaptosomal calcium metabolism during hypoxia and 3,4-diaminopyridine treatment.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Calcium; Hypoxia; Male; Mice; Synaptosomes | 1984 |
Myoneural effects of pethidine and droperidol.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Droperidol; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Meperidine; Muscle Contraction; Neostigmine; Neuromuscular Blocking Agents; Neuromuscular Junction; Rats; Rats, Inbred Strains; Time Factors; Tubocurarine; Verapamil | 1984 |
Strontium, nifedipine and 4-aminopyridine modify the time course of the action potential in cells from rat ventricular muscle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Nifedipine; Rats; Rats, Inbred Strains; Strontium; Time Factors | 1984 |
Differential effects of strychnine on two types of vascular muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aorta, Thoracic; Cardiovascular Agents; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Prazosin; Rats; Rats, Inbred Strains; Strychnine; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1984 |
Tetrodotoxin-resistant release of 3H-noradrenaline from the mouse vas deferens by high intensity electrical stimulation.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cations, Divalent; Drug Resistance; Electric Stimulation; Male; Mice; Mice, Inbred Strains; Narcotics; Norepinephrine; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Tritium; Vas Deferens | 1984 |
4-Aminopyridine-induced ultrastructural alterations of pinched-off nerve terminals from rat cerebral cortex.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cerebral Cortex; Electric Conductivity; Nerve Endings; Rats; Rats, Inbred Strains; Synaptosomes | 1984 |
Determination of 4-aminopyridine in horse plasma using gas-liquid chromatography.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Chromatography, Gas; Horses | 1984 |
Brain uptake indices of guanidine and 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Guanidine; Guanidines; Neuromuscular Junction; Rats | 1984 |
Antagonism of xylazine and ketamine anesthesia by 4-aminopyridine and yohimbine in geldings.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia, Intravenous; Animals; Body Temperature; Cats; Heart Rate; Horses; Ketamine; Male; Respiration; Thiazines; Xylazine; Yohimbine | 1984 |
The effect of 4-aminopyridine on the frequency-force relationship of isolated left atria of guinea-pigs.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cardiotonic Agents; Electric Stimulation; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine | 1984 |
Antagonistic effects of taurine and 4-aminopyridine on guinea pig ileum.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Atropine; Calcium; Female; Guinea Pigs; Ileum; Muscle Contraction; Taurine | 1984 |
Treatment of 4-aminopyridine-poisoning after oral overdose; a proposal.
Topics: 4-Aminopyridine; Administration, Oral; Adsorption; Aminopyridines; Charcoal; Humans | 1984 |
Evaluation of 4-aminopyridine and 3,4-diaminopyridine penetrability into cerebrospinal fluid in anesthetized rats.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Seizures | 1984 |
Extracellular ions and excitation-contraction coupling in frog twitch muscle fibres.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Aminopyridines; Animals; Arsenazo III; Calcium; Chlorides; In Vitro Techniques; Muscle Contraction; Muscles; Potassium; Sarcoplasmic Reticulum; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1984 |
Effects of coenzyme analogues on the binding of p-aminobenzoyl-L-glutamate and 2,4-diaminopyrimidine to Lactobacillus casei dihydrofolate reductase.
Topics: 4-Aminobenzoic Acid; 4-Aminopyridine; Aminobenzoates; Aminopyridines; Binding Sites; Glutamates; Kinetics; Lacticaseibacillus casei; Mathematics; NADP; Oxidation-Reduction; para-Aminobenzoates; Protein Binding; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thermodynamics | 1980 |
Studies of the effects of agents which alter calcium metabolism on acetylcholine turnover in the rat diaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Bungarotoxins; Calcimycin; Calcium; Diaphragm; Dinitrophenols; Guanidine; Guanidines; In Vitro Techniques; Lanthanum; Male; Ouabain; Rats; Tetraethylammonium Compounds; Theophylline | 1981 |
Dithiobiuret-induced muscle weakness in rats: evidence for a prejunctional effect.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Bungarotoxins; Choline; Hemicholinium 3; Male; Muscular Diseases; Neuromuscular Junction; Rats; Rats, Inbred Strains; Thiourea | 1982 |
Effects of 4-aminopyridine on rapidly and slowly conducting axons of rat corpus callosum.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Corpus Callosum; Electric Conductivity; Female; Rats; Rats, Inbred Strains | 1983 |
4-Aminopyridine and fiber potentials in rat and human hippocampal slices.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Hippocampus; Humans; Rats; Synapses | 1983 |
[Effects of 4-aminopyridine on nerve cells].
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Guinea Pigs; Neurons; Rats | 1983 |
Can 4-aminopyridine be used to reverse anaesthesia and muscle relaxation?
Topics: 4-Aminopyridine; Adolescent; Adult; Aminopyridines; Anesthetics; Drug Evaluation; Electrocardiography; Electroencephalography; Electromyography; Evoked Potentials; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Neostigmine; Neuromuscular Depolarizing Agents | 1983 |
High-performance liquid chromatographic determination of 4-aminopyridine and 3,4-diaminopyridine in rat cerebrospinal fluid and serum.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Animals; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Rats | 1983 |
Pharmacokinetics and pharmacodynamics of 4-aminopyridine in anesthetized dogs.
Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Dogs; Half-Life; Kinetics; Muscle Contraction; Muscle Relaxation; Neuromuscular Blocking Agents; Pancuronium; Structure-Activity Relationship | 1983 |
Kinetics and mechanism of hydroxy compound cinnamoylation in acetonitrile catalyzed by N-methylimidazole and 4-dimethylaminopyridine.
Topics: 1-Propanol; 4-Aminopyridine; Acetonitriles; Acylation; Aminopyridines; Cinnamates; Imidazoles; Kinetics | 1983 |
Solvent effects on the cinnamoylation of n-propyl alcohol catalyzed by N-methylimidazole and 4-dimethylaminopyridine.
Topics: 1-Propanol; 4-Aminopyridine; Acylation; Aminopyridines; Catalysis; Cinnamates; Imidazoles; Kinetics; Solvents | 1983 |
Effects of 4-aminopyridine on the cat superior cervical ganglion.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcium; Cats; Electric Stimulation; Electrophysiology; Female; Ganglia, Sympathetic; Kinetics; Magnesium; Male; Tubocurarine | 1983 |
Effects of agents that modulate potassium permeability on smooth muscle cells of the guinea-pig basilar artery.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Basilar Artery; Caffeine; Diltiazem; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Permeability; Potassium; Procaine; Tetraethylammonium; Tetraethylammonium Compounds | 1983 |
Effects of a 4-aminopyridine in calcium movements and changes of membrane potential in pinched-off nerve terminals from rat cerebral cortex.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cerebral Cortex; Fluorescent Dyes; Membrane Potentials; Rats; Synaptosomes | 1983 |
Effect of 4-aminopyridine on potassium permeability of canine tracheal smooth muscle cell membrane.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Cell Membrane Permeability; Dogs; Gallopamil; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth; Potassium; Radioisotopes; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Trachea | 1983 |
Amelioration of age-related neurochemical and behavioral deficits by 3,4-diaminopyridine.
Topics: 4-Aminopyridine; Acetylcholine; Aging; Amifampridine; Aminopyridines; Animals; Behavior, Animal; Male; Mice; Mice, Inbred BALB C; Nervous System | 1983 |
Block by phencyclidine of acetylcholine and barium induced adrenal catecholamine secretion.
Topics: 4-Aminopyridine; Acetylcholine; Adrenal Glands; Aminopyridines; Animals; Barium; Barium Compounds; Catecholamines; Cattle; Chlorides; In Vitro Techniques; Kinetics; Phencyclidine | 1983 |
The effects of 4-aminopyridine and tetrodotoxin on the release of acetylcholine from rat striatal slices.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcium; Corpus Striatum; Female; Male; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1983 |
Affinity chromatography with 25-hydroxycholecalciferol ester in the isolation of the binding protein for vitamin D and its metabolites from human serum.
Topics: 4-Aminopyridine; Aminopyridines; Calcifediol; Carrier Proteins; Chromatography, Affinity; Humans; Hydrogen-Ion Concentration; Hydroxycholecalciferols; Potassium Chloride; Succinic Anhydrides; Vitamin D; Vitamin D-Binding Protein | 1981 |
A method for the synthesis of isomerically pure saturated mixed-chain phosphatidylcholines.
Topics: 4-Aminopyridine; Aminopyridines; Anhydrides; Catalysis; Chlorides; Imidazoles; Isomerism; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipases A; Pyridines; Pyrrolidines | 1981 |
Characterization of end-plate conductance in transected frog muscle: modification by drugs.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electrophysiology; In Vitro Techniques; Magnesium; Membrane Potentials; Motor Endplate; Neural Conduction; Neuromuscular Junction; Rana pipiens; Tubocurarine | 1981 |
The effects of 3,4-diaminopyridine on acetylcholine release at the frog neuromuscular junction.
Topics: 4-Aminopyridine; Acetylcholine; Action Potentials; Amifampridine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Neuromuscular Junction; Rana temporaria; Time Factors; Vinblastine | 1980 |
4-Aminopyridine does not increase m.e.p.p. frequencies at junctions depolarized by potassium.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Motor Neurons; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Potassium; Rana pipiens | 1981 |
Contraction of the frog muscle in 4-aminopyridine by rapid cooling.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Caffeine; Cold Temperature; Dose-Response Relationship, Drug; In Vitro Techniques; Manganese; Membrane Potentials; Muscle Contraction; Neuromuscular Depolarizing Agents; Rana catesbeiana; Tetrodotoxin; Tubocurarine | 1981 |
Recording of pulmonary afferent activities from receptors in the perfused lung preparation of bullfrog and effects of drugs on the afferent activities.
Topics: 4-Aminopyridine; Afferent Pathways; Aminopyridines; Animals; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Perfusion; Rana catesbeiana; Temperature | 1981 |
Conduction failure in demyelination: is it inevitable?
Topics: 4-Aminopyridine; Aminopyridines; Animals; Anura; Axons; Cats; Central Nervous System; Demyelinating Diseases; History, 19th Century; History, 20th Century; Nerve Fibers, Myelinated; Neural Conduction; Peripheral Nerves; Rats; Remission, Spontaneous; Tetraethylammonium; Tetraethylammonium Compounds | 1981 |
Effects of 4-aminopyridine on insulin secretion and plasma glucose levels in intact and adrenalectomized-chemically sympathectomized mice.
Topics: 4-Aminopyridine; Adrenalectomy; Aminopyridines; Animals; Blood Glucose; Catecholamines; Female; Glucose; Insulin; Insulin Secretion; Mice; Mice, Inbred Strains; Neuromuscular Depolarizing Agents; Sympathectomy, Chemical | 1981 |
Antagonism of ketamine by 4-aminopyridine and physostigmine.
Topics: 4-Aminopyridine; Aminopyridines; Humans; Ketamine; Physostigmine | 1982 |
Cutaneous receptive field alterations induced by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Electric Stimulation; Evoked Potentials; Neurons; Pressoreceptors; Skin | 1982 |
Failure of 4-aminopyridine positive inotropic effect.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Dogs; Myocardial Contraction; Stimulation, Chemical | 1982 |
Voltage-dependent conductances in Limulus ventral photoreceptors.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Electric Conductivity; Horseshoe Crabs; Photoreceptor Cells; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1982 |
Synaptic and non-synaptic components of the dorsal horn potential in isolated hamster spinal cord.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Cricetinae; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Magnesium; Neurons, Afferent; Picrotoxin; Potassium; Spinal Cord; Synapses; Temperature; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1982 |
Existence of two transient outward currents in sheep cardiac Purkinje fibers.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Caffeine; Cardiovascular Agents; Electrophysiology; Heart; Heart Conduction System; Purkinje Fibers; Sheep | 1982 |
4-Aminopyridine kinetics.
Topics: 4-Aminopyridine; Administration, Oral; Adolescent; Adult; Aminopyridines; Blood Proteins; Female; Humans; Injections, Intravenous; Kinetics; Male; Protein Binding; Saliva | 1982 |
4-Aminopyridine tablets; a method for the preparation. In-vitro and in-vivo studies.
Topics: 4-Aminopyridine; Adolescent; Adult; Aminopyridines; Drug Compounding; Humans; Male; Tablets | 1982 |
Membrane currents, contractions, and aftercontractions in cardiac Purkinje fibers.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cardiovascular Agents; Heart Conduction System; Membrane Potentials; Myocardial Contraction; Purkinje Fibers; Sheep | 1982 |
Intracellular analysis of a postsynaptic action of adenosine in the rat hippocampus.
Topics: 4-Aminopyridine; Adenosine; Aminopyridines; Animals; Cobalt; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Synapses | 1982 |
Effects of 4-aminopyridine on acetylcholine output from the cerebral cortex of the rat in vivo.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Anesthesia; Animals; Blood Pressure; Cerebral Cortex; Male; Morphine; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains | 1982 |
Convulsant actions of 4-aminopyridine on the guinea-pig olfactory cortex slice.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Central Nervous System; Cerebral Cortex; Convulsants; Evoked Potentials; Female; Functional Laterality; Guinea Pigs; Male; Membrane Potentials; Neurons; Olfactory Pathways | 1982 |
Ion-pair high-performance liquid chromatographic assay of 4-aminopyridine in serum.
Topics: 4-Aminopyridine; Aminopyridines; Chromatography, High Pressure Liquid; Humans; Reference Values | 1982 |
Development of cross-tolerance to 5-hydroxytryptamine in organotypic cultures of mouse spinal cord-ganglia during chronic exposure to morphine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Drug Tolerance; Ganglia, Spinal; Mice; Morphine; Naloxone; Organ Culture Techniques; Serotonin; Spinal Cord | 1982 |
Reversibility of kanamycin-induced neuromuscular and cardiovascular depressions by 4-aminopyridine, in comparison with neostigmine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cardiovascular System; Depression, Chemical; Kanamycin; Male; Neostigmine; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Rats; Rats, Inbred Strains; Tubocurarine | 1982 |
Effect of 4-aminopyridine on the rat superior cervical ganglion.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Male; Membrane Potentials; Neural Conduction; Neuromuscular Depolarizing Agents; Perfusion; Rats; Rats, Inbred Strains; Sympathectomy; Tubocurarine | 1982 |
Effects of 4-aminopyridine on inward rectifying and pacemaker currents of cardiac Purkinje fibres.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Dose-Response Relationship, Drug; Heart Conduction System; In Vitro Techniques; Neuromuscular Depolarizing Agents; Potassium; Purkinje Fibers; Sheep | 1982 |
Synthesis of N-acylglutathione derivatives by dimethylaminopyridine catalysis.
Topics: 4-Aminopyridine; Acylation; Aminopyridines; Catalysis; Glutathione; Methods | 1982 |
Effect of 4-aminopyridine and verapamil on the inhibitory action of normorphine on the guinea-pig ileum.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Calcium; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Verapamil | 1982 |
Effect of 4-aminopyridine on end-plate receptor desensitization caused by carbachol.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Chloride; Carbachol; Crotoxin; Drug Interactions; In Vitro Techniques; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Separation of the oscillatory current from other currents in cardiac Purkinje fibres.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cesium; Electric Conductivity; Heart Conduction System; Neuromuscular Depolarizing Agents; Purkinje Fibers; Sheep | 1982 |
Control of human airway smooth muscle: in vitro studies.
Topics: 4-Aminopyridine; Aminopyridines; Arachidonic Acids; Dopamine; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Norepinephrine; Peptides; Purines; Respiratory Physiological Phenomena; Serotonin; Sympathetic Nervous System; Tetraethylammonium; Tetraethylammonium Compounds | 1982 |
An electroencephalographic study of 4-aminopyridine.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Cardiovascular System; Diazepam; Electroencephalography; Humans; Male; Neuromuscular Depolarizing Agents | 1982 |
The effect of calcium, neostigmine and 4-aminopyridine upon respiratory arrest and depression of cardiovascular functions after aminoglycosidic antibiotics.
Topics: 4-Aminopyridine; Aminoglycosides; Aminopyridines; Animals; Anti-Bacterial Agents; Calcium; Diaphragm; Drug Interactions; Hemodynamics; Neostigmine; Neuromuscular Blocking Agents; Rats; Respiration | 1982 |
Antagonism of 4-aminopyridine to ketamine-diazepam anesthesia in children.
Topics: 4-Aminopyridine; Aminopyridines; Child; Child, Preschool; Diazepam; Humans; Infant; Ketamine; Neuromuscular Depolarizing Agents | 1980 |
Myelinated central vertebrate axon lacks voltage-sensitive potassium conductance.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Electric Conductivity; Goldfish; Myelin Sheath; Potassium; Tetraethylammonium Compounds | 1981 |
Cholinergic effect of 4-aminopyridine and adrenergic effect of 4-methyl-2-aminopyridine in cardiac muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Male; Myocardial Contraction; Parasympathomimetics; Picolines; Propranolol; Rabbits; Stimulation, Chemical; Sympathomimetics | 1981 |
Inward rectification in mouse macrophages: evidence for a negative resistance region.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cells, Cultured; Macrophages; Membrane Potentials; Mice; Mice, Inbred Strains; Neuromuscular Depolarizing Agents; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1981 |
Actions of 4-aminopyridine on the cardiovascular systems of anaesthetized cats and dogs.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cardiovascular Agents; Cats; Dogs; Electrocardiography; Female; Heart Rate; Hemodynamics; Male | 1981 |
Pharmacokinetics of 4-aminopyridine in human volunteers. A preliminary study using a new GLC method for its estimation.
Topics: 4-Aminopyridine; Adult; Aminopyridines; Chromatography, Gas; Humans; Kinetics; Time Factors | 1981 |
The effects of 4-aminopyridine on the isolated vas deferens and its effects on the inhibitory properties of adenosine, morphine, noradrenaline and gamma-aminobutyric acid.
Topics: 4-Aminopyridine; Adenosine; Aminopyridines; Animals; Calcium; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium Chloride; Quinidine; Tetraethylammonium Compounds; Vas Deferens | 1981 |
Effect of 4-aminopyridine on cardiovascular functions in the dog.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Blood Pressure; Cardiovascular System; Dogs; Neuromuscular Depolarizing Agents | 1981 |
Modulation of synaptic output by the transient outward potassium current in aplysia.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Aplysia; Membrane Potentials; Neuromuscular Depolarizing Agents; Potassium; Synapses | 1981 |
4-aminopyridine; analysis of the substance and a method for the preparation of a solution for injection in man.
Topics: 4-Aminopyridine; Aminopyridines; Drug Compounding; Injections; Solutions | 1981 |
4-Aminopyridine reveals presynaptic GABA actions in rat sympathetic ganglia.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Rats; Synapses | 1981 |
The effect of 4-aminopyridine on the spinal locomotor rhythm induced by L-DOPA.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Dose-Response Relationship, Drug; Levodopa; Locomotion; Movement; Muscles; Neuromuscular Depolarizing Agents; Nialamide; Spinal Cord | 1981 |
Determination of 4-aminopyridine in plasma.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Chromatography, Gas; Humans; Microchemistry | 1981 |
Use of 4-aminopyridine to reverse morphine-induced respiratory depression in man.
Topics: 4-Aminopyridine; Adolescent; Adult; Aminopyridines; Anesthesia, Intravenous; Depression, Chemical; Female; Humans; Male; Middle Aged; Morphine; Respiration; Respiratory Insufficiency; Tidal Volume | 1981 |
Suspected 4-aminopyridine toxicosis in cattle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cattle; Cattle Diseases; Pesticides | 1981 |
The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Diphtheria Toxin; Hot Temperature; Manganese; Nerve Fibers, Myelinated; Neuromuscular Depolarizing Agents; Rats; Spinal Nerve Roots; Tetraethylammonium Compounds | 1981 |
Residues of 4-aminopyridine in poisoned birds.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Birds; Columbidae; Lethal Dose 50; Pesticide Residues; Tissue Distribution | 1981 |
Effect of 4-aminopyridine on nerve terminal action potentials.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Anura; Calcium; In Vitro Techniques; Nerve Endings; Neuromuscular Junction; Osmolar Concentration | 1981 |
Adrenergic nerve-blocking activity of a new guanidine derivative.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cats; Electric Stimulation; Guanidine; Guanidines; Norepinephrine; Spleen; Sympatholytics; Tetraethylammonium Compounds | 1981 |
Effects of 4-aminopyridine on the adrenergic nerve terminals of rabbit arteries.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Arteries; Electric Stimulation; In Vitro Techniques; Male; Nerve Endings; Nicotine; Norepinephrine; Rabbits; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 1981 |
Effect of taurine on seizures induced by 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Mice; Seizures; Synaptosomes; Taurine | 1981 |
Dopamine release induced by electrical stimulation of microdissected caudate-putamen and substantia nigra of the rat brain.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Caudate Nucleus; Dopamine; Electric Stimulation; Male; Methods; Microsurgery; Putamen; Rats; Rats, Inbred Strains; Substantia Nigra; Tetrodotoxin | 1981 |
Potentiating effects of 5-hydroxytryptamine and histamine on nerve stimulation-induced contractions of the rabbit mesenteric artery.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Drug Interactions; Electric Stimulation; Female; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Serotonin | 1981 |
Effect of tetraethylammonium, 4-aminopyridine, cesium and magnesium on slow responses in the guinea pig papillary muscle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Calcium; Cesium; Guinea Pigs; Heart Conduction System; Magnesium; Neuromuscular Depolarizing Agents; Norepinephrine; Papillary Muscles; Strontium; Tetraethylammonium; Tetraethylammonium Compounds | 1981 |
Ca-K bi-ionic action potential in squid giant axons.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Axons; Calcium; Cobalt; Decapodiformes; Gallopamil; Manganese; Membrane Potentials; Neuromuscular Depolarizing Agents; Potassium; Tetrodotoxin | 1981 |
Effects of tetraethylammonium and 4-aminopyridine upon canine sinus node.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Membrane Potentials; Myocardial Contraction; Neural Conduction; Neuromuscular Depolarizing Agents; Potassium; Propranolol; Sinoatrial Node; Tetraethylammonium Compounds | 1981 |
Evidence for a function of calcium influx in the stimulation of hormone release fron the parathyroid gland in the goat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Calcium Channel Blockers; Female; Goats; Parathyroid Glands; Parathyroid Hormone; Stimulation, Chemical; Strontium; Verapamil | 1981 |
Effects of 4-aminopyridine on contractile response and action potential of rabbit papillary muscle.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Dose-Response Relationship, Drug; Myocardial Contraction; Neuromuscular Depolarizing Agents; Papillary Muscles; Rabbits; Stimulation, Chemical | 1981 |
Effect of rate-dependent changes in the transient outward current on the action potential in sheep Purkinje fibres.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Electric Stimulation; Heart Conduction System; In Vitro Techniques; Kinetics; Membrane Potentials; Purkinje Fibers; Sheep | 1981 |
Behavioral and cardiorespiratory responses to 4-aminopyridine in healthy awake horses.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Behavior, Animal; Cardiovascular System; Horses; Injections, Intravenous; Neuromuscular Depolarizing Agents; Respiration | 1981 |
Calcium current inactivation in identified neurones of Helix aspersa.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium; Helix, Snails; In Vitro Techniques; Membrane Potentials; Neurons; Potassium; Quinine; Tetraethylammonium Compounds | 1981 |
Enhancement of peptide coupling reactions by 4-dimethylaminopyridine.
Topics: 4-Aminopyridine; Amino Acids; Aminopyridines; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Peptides | 1981 |
Actions of 4-aminopyridine on vascular smooth muscle tissues of the guinea-pig.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Portal Vein; Procaine; Pulmonary Artery | 1980 |
Do neostigmine and 4-aminopyridine inhibit the antibacterial activity of antibiotics?
Topics: 4-Aminopyridine; Aminopyridines; Anti-Bacterial Agents; Bacteria; Microbial Sensitivity Tests; Neostigmine; Neuromuscular Junction | 1980 |
4-aminopyridine fails to induce porcine malignant hyperthermia.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Malignant Hyperthermia; Swine | 1980 |
4-Aminopyridine blockade of neuronal depressant responses to adenosine triphosphate.
Topics: 4-Aminopyridine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminopyridines; Animals; Glutamates; Male; Neurons; Rats; Tetraethylammonium Compounds | 1980 |
[Effects of intracellular 4-aminopyridine and tetraethylammonium load on action potentials in the rabbit atrial myocardium].
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Animals; Atrial Function; In Vitro Techniques; Membrane Potentials; Microelectrodes; Models, Cardiovascular; Myocardium; Rabbits; Tetraethylammonium Compounds | 1980 |
Reversal of dantrolene sodium-induced depression of skeletal muscle in the cat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Chloride; Cats; Cevanes; Dantrolene; Electromyography; Female; Germine Acetates; Male; Muscle Contraction; Neostigmine | 1981 |
[Electroencephalographic Investigations of 4-Aminopyridine (author's transl)].
Topics: 4-Aminopyridine; Aminopyridines; Animals; Brain; Electroencephalography; Male; Rats | 1980 |
Antagonism of ketamine by 4-aminopyridine and physostigmine.
Topics: 4-Aminopyridine; Aminopyridines; Drug Interactions; Humans; Ketamine; Physostigmine | 1981 |
Liquid-chromatographic determination of 4-aminopyridine in serum, saliva, and urine.
Topics: 4-Aminopyridine; Aminopyridines; Chromatography, High Pressure Liquid; Humans; Saliva | 1981 |
4-Aminopyridine block of the noninactivating cloned K+ channel Kv1.5 expressed in Xenopus oocytes.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Electric Stimulation; Hydrogen-Ion Concentration; Kinetics; Models, Cardiovascular; Myocardium; Oocytes; Osmolar Concentration; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Xenopus laevis | 1995 |
Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Baclofen; GABA-B Receptor Antagonists; Guinea Pigs; Hippocampus; Organophosphorus Compounds; Potassium Channels; Receptors, GABA-B | 1994 |
On the mechanism of 4-aminopyridine action on the cloned mouse brain potassium channel mKv1.1.
Topics: 4-Aminopyridine; Amino Acid Sequence; Aminopyridines; Animals; Brain Chemistry; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Potassium Channel Blockers; Potassium Channels; Transfection | 1994 |
Aminopyridine block of potassium channels in mouse neuroblastoma cells.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Binding Sites; Mice; Neuroblastoma; Potassium Channels; Tumor Cells, Cultured | 1993 |
4-Aminopyridine derivatives with antiamnesic activity.
Topics: 4-Aminopyridine; Alzheimer Disease; Aminopyridines; Amnesia; Animals; Avoidance Learning; Carbon Dioxide; Indoles; Male; Mice; Nootropic Agents; Piracetam | 2000 |
Selective effects of subarachnoid hemorrhage on cerebral vascular responses to 4-aminopyridine in rats.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Aminopyridines; Animals; Basilar Artery; Blood Pressure; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Membrane Potentials; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Serotonin; Subarachnoid Hemorrhage; Tetraethylammonium; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Validation of a CE assay for the analysis of isomeric aminopyridines and diaminopyridines.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Electrophoresis, Capillary; Isomerism; Reproducibility of Results; Sensitivity and Specificity | 2001 |
The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Analysis of Variance; Animals; Aorta; Arginine; Barium; Endothelium, Vascular; Glyburide; Guanidines; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Tolbutamide; Vasodilator Agents | 2002 |
Surface complexation modeling of the sorption of 2-, 3-, and 4-aminopyridine by montmorillonite.
Topics: 4-Aminopyridine; Adsorption; Aminopyridines; Bentonite; Fluorescent Dyes; Kaolin; Kinetics; Macromolecular Substances; Models, Chemical; Potassium Channel Blockers; Spectroscopy, Fourier Transform Infrared; Surface Properties | 2005 |
Studies on some salicylaldehyde Schiff base derivatives and their complexes with Cr(III), Mn(II), Fe(III), Ni(II) and Cu(II).
Topics: 4-Aminopyridine; Aldehydes; Aminopyridines; Aniline Compounds; Chromium; Copper; Electron Probe Microanalysis; Ethanol; Hydrogen-Ion Concentration; Iron; Kinetics; Manganese; Molecular Structure; Nickel; Nitrogen; Pyrimidines; Schiff Bases; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Thermogravimetry; Transition Elements | 2007 |
Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Cell Line; CHO Cells; Cricetinae; Cricetulus; Humans; Positron-Emission Tomography; Receptors, Neuropeptide Y; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2009 |
Anharmonic vibrational analysis of 3,4-diaminopyridine and 3-aminopyridine by density functional theory calculations.
Topics: 4-Aminopyridine; Amifampridine; Aminopyridines; Models, Molecular; Models, Theoretical; Molecular Structure; Potassium Channel Blockers; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; Vibration | 2010 |
Regioselective cobalt-catalyzed formation of bicyclic 3- and 4-aminopyridines.
Topics: 4-Aminopyridine; Aminopyridines; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cobalt; Models, Molecular; Molecular Structure; Stereoisomerism | 2011 |
DFT studies on one-electron oxidation and one-electron reduction for 2- and 4-aminopyridines.
Topics: 4-Aminopyridine; Aminopyridines; Aniline Compounds; Electrons; Entropy; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Quantum Theory; Stereoisomerism | 2012 |
M-channels modulate network excitatory activity induced by 4-aminopyridine in immature rat substantia gelatinosa in vitro.
Topics: 4-Aminopyridine; Action Potentials; Aminopyridines; Analgesics; Animals; Animals, Newborn; Anthracenes; Biological Clocks; Biophysical Phenomena; Carbamates; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vitro Techniques; Indoles; Male; Membrane Transport Modulators; Nerve Net; Neurons; Phenylenediamines; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Substantia Gelatinosa | 2013 |
Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.
Topics: 4-Aminopyridine; Administration, Oral; Aminopyridines; Animals; Benzamides; Biological Availability; Crystallography, X-Ray; Interferon-gamma; Interleukin-12; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Mice; Microsomes, Liver; Models, Molecular; Protein Binding; Rats; STAT4 Transcription Factor; Stereoisomerism; Structure-Activity Relationship; TYK2 Kinase | 2013 |
Two new zinc(II) acetates with 3- and 4-aminopyridine: syntheses and structural properties.
Topics: 4-Aminopyridine; Acetates; Aminopyridines; Crystallography, X-Ray; Hydrogen Bonding; Zinc Acetate | 2015 |
Acrolein-mediated conduction loss is partially restored by K⁺ channel blockers.
Topics: 4-Aminopyridine; Acrolein; Action Potentials; Aminopyridines; Animals; Male; Myelin Sheath; Neural Conduction; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Spinal Cord | 2016 |
4-Aminopyridine based amide derivatives as dual inhibitors of tissue non-specific alkaline phosphatase and ecto-5'-nucleotidase with potential anticancer activity.
Topics: 4-Aminopyridine; 5'-Nucleotidase; Alkaline Phosphatase; Aminopyridines; Antineoplastic Agents; Apoptosis; Benzamides; Carboplatin; Catalytic Domain; Cell Cycle Checkpoints; Cell Line, Tumor; DNA; Enzyme Inhibitors; Humans; Hydrogen Bonding; Molecular Docking Simulation; Structure-Activity Relationship | 2018 |
Parallel Evaluation of Two Potassium Channel Blockers in Restoring Conduction in Mechanical Spinal Cord Injury in Rat.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Male; Neural Conduction; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries | 2018 |
Aminopiridines in the treatment of multiple sclerosis and other neurological disorders.
Topics: 4-Aminopyridine; Aminopyridines; Humans; Lambert-Eaton Myasthenic Syndrome; Multiple Sclerosis; Nervous System Diseases; Potassium Channel Blockers; Quality of Life | 2020 |