alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate has been researched along with isoxazoles in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (23.81) | 18.2507 |
2000's | 26 (61.90) | 29.6817 |
2010's | 6 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Benvenga, MJ; Leander, JD; Ornstein, PL | 1 |
Abdulla, FA; Calaminici, MR; Gray, JA; Raevsky, VV; Sinden, JD; Stephenson, JD | 1 |
Steppuhn, KG; Turski, L | 1 |
Arnt, J; Krogsgaard-Larsen, P; Lenz, SM; Madsen, U; Sánchez, C | 1 |
Ballyk, BA; Bath, CP; Bleakman, D; Clarke, VR; Collingridge, GL; Davies, CH; Hoo, KH; Kamboj, RK; Lodge, D; Mandelzys, A; Ornstein, PL; Pellizzari, A; Schoepp, DD; Sharpe, EF; Thomas, J | 1 |
Sakmann, B; Schiller, J; Schiller, Y; Stuart, G | 1 |
Curry, K; Pajouhesh, H | 1 |
Cui, C; Mayer, ML | 1 |
Borre, L; Ebert, B; Egebjerg, J; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U; Stensbøl, TB | 1 |
Bleakman, D; Deverill, M; Ellis, GJ; Hawes, CR; Hoo, K; Krogsgaard-Larsen, P; Legutko, B; Rizkalla, G; Skolnick, P; Stensbol, TB | 1 |
Herrera, MT; Lerma, J; Nieto, MA; Paternain, AV | 1 |
Lerma, J; López-García, JC; Rodríguez-Moreno, A | 1 |
Baraldi, M; De Micheli, C; De Sarro, A; De Sarro, G; Grasso, S; Micale, N; Puja, G; Zappalà, M | 1 |
Huettner, JE; Wilding, TJ | 1 |
Chen, A; Li, H; Rogawski, MA; Wei, ML; Xing, G | 1 |
Kristensen, BW; Noraberg, J; Zimmer, J | 1 |
Bortolotto, ZA; Collingridge, GL; Delany, C; J Clarke, VR; Lauri, SE; Ornstein, PL; T R Isaac, J | 1 |
Fedinec, AL; Leffler, CW; Robinson, JS | 1 |
Clarke, VR; Collingridge, GL | 2 |
Ben-Ari, Y; Cossart, R; Hirsch, J; Khalilov, I | 1 |
De Micheli, C; De Sarro, A; De Sarro, G; Ferreri, G; Grasso, S; Micale, N; Puja, G; Toma, L; Zappalà, M | 1 |
Camón, L; de Vera, N; Martínez, E; Vivó, M | 1 |
Egebjerg, J; Krogsgaard-Larsen, P; Liljefors, T; Nielsen, MM | 1 |
Wu, DC; Yu, LC; Zhou, N | 1 |
Egebjerg, J; Gouaux, E; Hogner, A; Kastrup, JS; Lunn, ML; Stensbøl, TB | 1 |
Kristensen, AS; Madsen, U; Mathiesen, C; Nielsen, EØ; Peters, D; Valgeirsson, J; Varming, T | 1 |
Hernández, ME; López-Bayghen, E; Méndez, JA; Ortega, A; Rojas, F | 1 |
Breustedt, J; Schmitz, D | 1 |
Jung, SY; Kim, YT; Park, YJ; Seo, WS; Suh, CK | 1 |
O'neill, MF; Ornstein, PL; Osborne, DJ; Sanger, G; Woodhouse, SM | 1 |
Ko, SW; Toyoda, H; Wu, LJ; Zhao, MG; Zhuo, M | 1 |
Bräuner-Osborne, H; Egebjerg, J; Frølund, B; Greenwood, JR; Holm, MM; Krogsgaard-Larsen, P; Madsen, U; Nielsen, B; Stensbøl, TB | 1 |
Lauri, SE; Malkki, H; Sallert, M; Segerstråle, M; Taira, T | 1 |
Albrecht, D; Drephal, C; Schubert, M | 1 |
Liu, Y; Xu, J; Zhang, GY | 1 |
Li, JM; Li, Q; Peng, F; Yao, ZP; Zhou, D | 1 |
Duncan, GE; Koller, BH; Moy, SS | 1 |
Han, D; Liu, Y; Lv, Q; Wang, Y; Xu, J; Zhang, GY; Zong, YY | 1 |
Li, C; Zhang, GY; Zhang, HJ | 1 |
Ishikura, T; Maruyama, T; Matsuura, T; Ohbuchi, T; Ohkubo, J; Suzuki, H; Ueta, Y; Yoshimura, M | 1 |
Fritsch, B; Gasior, M; Kaminski, RM; Reis, J; Rogawski, MA | 1 |
42 other study(ies) available for alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate and isoxazoles
Article | Year |
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Schedule-controlled behavioral effects of the selective 2-amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic acid antagonist LY293558 in pigeons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Columbidae; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoquinolines; Isoxazoles; Male; N-Methylaspartate; Propionates; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Stereoisomerism; Tetrazoles | 1995 |
An iontophoretic study of the effects of alpha-amino-hydroxy-5-methyl-4-isoxazole propionic acid lesions of the nucleus basalis magnocellularis on cholinergic and GABAergic influences on frontal cortex neurones of rats.
Topics: Acetylcholine; Animals; Bicuculline; Carbachol; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Iontophoresis; Isoxazoles; Male; Medulla Oblongata; Neurons; Parasympathetic Nervous System; Propionates; Rats; Rats, Sprague-Dawley | 1994 |
Modulation of the seizure threshold for excitatory amino acids in mice by antiepileptic drugs and chemoconvulsants.
Topics: Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Drug Administration Routes; Isoxazoles; Kainic Acid; Male; Mice; N-Methylaspartate; Propionates; Receptors, Glutamate; Seizures | 1993 |
Differentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Convulsants; Cues; Discrimination Learning; Discrimination, Psychological; Excitatory Amino Acid Agonists; Isoxazoles; Ligands; Male; Mice; N-Methylaspartate; Propionates; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1995 |
A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission.
Topics: Animals; Cell Line; Cloning, Molecular; Excitatory Amino Acid Agonists; Hippocampus; Humans; Isoquinolines; Isoxazoles; Kainic Acid; Neural Inhibition; Propionates; Rats; Receptors, GABA-A; Receptors, Kainic Acid; Synapses; Tetrazoles | 1997 |
Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons.
Topics: Action Potentials; Animals; Axons; Calcium; Dendrites; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Fluorescence; In Vitro Techniques; Isoxazoles; Neocortex; Patch-Clamp Techniques; Propionates; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate | 1997 |
Pharmacological profile of the isomers of the GluR-specific agonist ATPA.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Kynurenic Acid; Propionates; Quinoxalines; Rats; Receptors, Glutamate; Stereoisomerism | 1998 |
Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7.
Topics: Alanine; Alternative Splicing; Cell Line; Excitatory Amino Acid Agonists; Genetic Variation; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Humans; Isoxazoles; Kainic Acid; Macromolecular Substances; Membrane Potentials; Mutagenesis, Site-Directed; Propionates; Pyrimidines; Receptors, Kainic Acid; Recombinant Proteins | 1999 |
Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Isoxazoles; Molecular Conformation; Oocytes; Propionates; Quinoxalines; Radioligand Assay; Rats; Receptors, AMPA; Recombinant Fusion Proteins; Stereoisomerism; Tritium; Xenopus | 1999 |
[3H]ATPA: a high affinity ligand for GluR5 kainate receptors.
Topics: Animals; Animals, Newborn; Cell Line; Excitatory Amino Acid Agonists; Ganglia, Spinal; Humans; Isoxazoles; Kainic Acid; Neurons; Propionates; Rats; Receptors, Kainic Acid | 1999 |
GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Gene Expression; GluK2 Kainate Receptor; Glutamic Acid; Hippocampus; Ion Channel Gating; Isoxazoles; Kainic Acid; Neurons; Propionates; Protein Structure, Tertiary; Rats; Receptors, Kainic Acid; RNA, Messenger; Structure-Activity Relationship | 2000 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Synthesis and anticonvulsant activity of novel and potent 6,7-methylenedioxyphthalazin-1(2H)-ones.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cells, Cultured; Convulsants; Drug Evaluation, Preclinical; Electroshock; Excitatory Amino Acid Agonists; Isoxazoles; Kainic Acid; Mice; Mice, Inbred DBA; Neurons; Patch-Clamp Techniques; Pentylenetetrazole; Phthalazines; Propionates; Receptors, AMPA; Receptors, Kainic Acid; Seizures; Structure-Activity Relationship | 2000 |
Functional diversity and developmental changes in rat neuronal kainate receptors.
Topics: Aging; Animals; Animals, Newborn; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; Excitatory Amino Acid Agonists; Ganglia, Spinal; Hippocampus; Isoxazoles; Kainic Acid; Neurons; Propionates; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Spinal Cord | 2001 |
Kainate receptor-mediated heterosynaptic facilitation in the amygdala.
Topics: Amygdala; Animals; Calcium; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; In Vitro Techniques; Isoxazoles; Male; Neurons; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Synapses; Synaptic Transmission | 2001 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
Synaptic activation of a presynaptic kainate receptor facilitates AMPA receptor-mediated synaptic transmission at hippocampal mossy fibre synapses.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Isoxazoles; Mossy Fibers, Hippocampal; Propionates; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Synapses; Synaptic Transmission | 2001 |
Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Arterioles; Carbon Monoxide; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heme Oxygenase (Decyclizing); Isoxazoles; Mesoporphyrins; Metalloporphyrins; Propionates; Protoporphyrins; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Swine; Vasodilation | 2002 |
Characterisation of the effects of ATPA, a GLU(K5) receptor selective agonist, on excitatory synaptic transmission in area CA1 of rat hippocampal slices.
Topics: Animals; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Isoquinolines; Isoxazoles; Propionates; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission | 2002 |
Paradoxical anti-epileptic effects of a GluR5 agonist of kainate receptors.
Topics: Animals; Animals, Newborn; Anticonvulsants; Hippocampus; Interneurons; Isoxazoles; Neural Inhibition; Propionates; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Seizures | 2002 |
Novel potent AMPA/kainate receptor antagonists: synthesis and anticonvulsant activity of a series of 2-[(4-alkylsemicarbazono)-(4-amino-phenyl)methyl]-4,5-methylenedioxyphenylacetic acid alkyl esters.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Cerebellum; Dioxoles; Excitatory Amino Acid Antagonists; Isoxazoles; Kainic Acid; Male; Mice; Mice, Inbred DBA; Models, Molecular; Motor Activity; Neurons; Patch-Clamp Techniques; Phenylacetates; Propionates; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Seizures; Semicarbazones; Structure-Activity Relationship | 2002 |
Lesion of substantia nigra pars compacta by the GluR5 agonist ATPA.
Topics: Animals; Dopamine; Isoxazoles; Male; Motor Activity; Neurons; Propionates; Rats; Rats, Wistar; Receptors, Kainic Acid; Substantia Nigra | 2002 |
The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Isoxazoles; Models, Molecular; Mutagenesis; Propionates; Receptors, AMPA; Receptors, Kainic Acid; Serine; Xenopus laevis | 2003 |
Anti-nociceptive effect induced by intrathecal injection of ATPA, an effect enhanced and prolonged by concanavalin A.
Topics: Analgesics; Animals; Concanavalin A; Drug Synergism; Injections, Spinal; Isoxazoles; Male; Pain Measurement; Propionates; Rats; Rats, Wistar; Receptors, Kainic Acid | 2003 |
Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity.
Topics: Binding Sites; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Agonists; Isoxazoles; Ligands; Models, Molecular; Propionates; Protein Conformation; Protein Subunits; Receptors, AMPA; Stereoisomerism; Zinc | 2003 |
2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.
Topics: Animals; Benzoates; Cell Line; Excitatory Amino Acid Agonists; Humans; Isoxazoles; Mice; Muscle Rigidity; Patch-Clamp Techniques; Propionates; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Kainic Acid; Urea | 2003 |
Glutamate regulates Oct-2 DNA-binding activity through alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptors in cultured chick Bergmann glia cells.
Topics: Animals; Blotting, Western; Carcinogens; Carrier Proteins; Cells, Cultured; Chick Embryo; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Glutamic Acid; Humans; Immunohistochemistry; Isoxazoles; Neuroglia; Octamer Transcription Factor-2; Precipitin Tests; Propionates; Receptors, Glutamate; Silencer Elements, Transcriptional; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors | 2004 |
Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices.
Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Membrane Potentials; Neural Inhibition; Propionates; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission; Valine | 2004 |
Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids, Dicarboxylic; Animals; Benzodiazepines; Cyclopropanes; Excitatory Postsynaptic Potentials; Gene Deletion; GluK2 Kainate Receptor; Glycine; Isoquinolines; Isoxazoles; Kainic Acid; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; Neuronal Plasticity; Patch-Clamp Techniques; Potassium; Propionates; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission | 2004 |
Effects of Na+-Ca2+ exchanger activity on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolone-propionate-induced Ca2+ influx in cerebellar Purkinje neurons.
Topics: Agatoxins; Animals; Animals, Newborn; Bepridil; Calbindins; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Diagnostic Imaging; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Isoxazoles; Microscopy, Confocal; Oligonucleotides, Antisense; Polyamines; Propionates; Purkinje Cells; Quinoxalines; Rats; S100 Calcium Binding Protein G; Sodium; Sodium Channel Blockers; Sodium-Calcium Exchanger; Thiourea | 2005 |
Locomotor activity detects subunit-selective effects of agonists and decahydroisoquinoline antagonists at AMPA/kainic acid ionotropic glutamate receptors in adult rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoquinolines; Isoxazoles; Kainic Acid; Male; Motor Activity; Propionates; Rats; Receptors, AMPA; Receptors, Kainic Acid | 2005 |
Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzodiazepines; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GluK2 Kainate Receptor; Gyrus Cinguli; In Vitro Techniques; Isoxazoles; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Propionates; Receptors, Kainic Acid; Synaptic Transmission | 2005 |
Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Computer Simulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoxazoles; Models, Molecular; Oocytes; Patch-Clamp Techniques; Propionates; Rats; Receptors, Glutamate; Xenopus laevis | 2005 |
Effects of the kainate receptor agonist ATPA on glutamatergic synaptic transmission and plasticity during early postnatal development.
Topics: Aging; Animals; Animals, Newborn; Electrophysiology; Excitatory Amino Acid Agonists; Glutamates; Hippocampus; In Vitro Techniques; Isoxazoles; Neuronal Plasticity; Propionates; Rats; Rats, Wistar; Receptors, Kainic Acid; Signal Transduction; Synapses; Synaptic Transmission | 2007 |
Gender-dependent ATPA-induced changes in long-term potentiation in the rat lateral amygdala.
Topics: Amygdala; Animals; Female; Isoxazoles; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinases; Propionates; Rats; Rats, Wistar; Receptors, Kainic Acid; Sex Factors | 2008 |
Neuroprotection of GluR5-containing kainate receptor activation against ischemic brain injury through decreasing tyrosine phosphorylation of N-methyl-D-aspartate receptors mediated by Src kinase.
Topics: Animals; Brain; Disks Large Homolog 4 Protein; Intracellular Signaling Peptides and Proteins; Ischemia; Isoxazoles; Male; Membrane Proteins; Patch-Clamp Techniques; Phosphorylation; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Tyrosine | 2008 |
[Different expression of GluR5 and GluR6 in rat astrocyte induced with coriaria lactone and ATPA].
Topics: Animals; Animals, Newborn; Astrocytes; Epilepsy; GluK2 Kainate Receptor; Isoxazoles; Lactones; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; RNA, Messenger | 2010 |
Effects of the selective kainate receptor antagonist ACET on altered sensorimotor gating in a genetic model of reduced NMDA receptor function.
Topics: Alanine; Animals; Antipsychotic Agents; Carrier Proteins; Disease Models, Animal; Gene Knockdown Techniques; Isoxazoles; Mice; Nerve Tissue Proteins; Propionates; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Uracil | 2012 |
Neuroprotection of GluK1 kainate receptor agonist ATPA against ischemic neuronal injury through inhibiting GluK2 kainate receptor-JNK3 pathway via GABA(A) receptors.
Topics: Animals; Enzyme Activation; gamma-Aminobutyric Acid; GluK2 Kainate Receptor; Isoxazoles; Male; Mitogen-Activated Protein Kinase 10; Neurons; Neuroprotective Agents; Propionates; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Kainic Acid; Reperfusion Injury; Signal Transduction | 2012 |
ATPA induced GluR5-containing kainite receptor S-nitrosylation via activation of GluR5-Gq-PLC-IP(3)R pathway and signalling module GluR5·PSD-95·nNOS.
Topics: Animals; Apoptosis; Calcimycin; Calcium Signaling; Disks Large Homolog 4 Protein; GTP-Binding Protein alpha Subunits, Gq-G11; HEK293 Cells; Hippocampus; Humans; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Signaling Peptides and Proteins; Isoxazoles; Membrane Potentials; Membrane Proteins; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Propionates; Protein Multimerization; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Type C Phospholipases | 2012 |
Electrophysiological effects of kainic acid on vasopressin-enhanced green fluorescent protein and oxytocin-monomeric red fluorescent protein 1 neurones isolated from the supraoptic nucleus in transgenic rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; Animals; Arginine Vasopressin; Cell Separation; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Green Fluorescent Proteins; Isoxazoles; Kainic Acid; Luminescent Proteins; Neurons; Oxytocin; Patch-Clamp Techniques; Primary Cell Culture; Propionates; Rats; Rats, Transgenic; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Red Fluorescent Protein; Supraoptic Nucleus; Thymine | 2014 |
Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.
Topics: Amygdala; Animals; Epilepsy; Excitatory Amino Acid Agonists; GluK2 Kainate Receptor; Hippocampus; Isoxazoles; Mice; Mice, Knockout; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Seizures | 2014 |