alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's6 (40.00)18.2507
2000's8 (53.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brehm, L; Christensen, IT; Ebert, B; Krogsgaard-Larsen, P; Madsen, U; Nielsen, B1
Honoré, T; Krogsgaard-Larsen, P; Lauridsen, J1
Didriksen, M; Ebert, B; Engesgaard, A; Frølund, B; Jaroszewski, JW; Krogsgaard-Larsen, P; Matzen, L1
Benvenga, MJ; Leander, JD; Ornstein, PL1
Arnt, J; Krogsgaard-Larsen, P; Lenz, SM; Madsen, U; Sánchez, C1
Curry, K; Pajouhesh, H1
Herrera, MT; Lerma, J; Nieto, MA; Paternain, AV1
Lerma, J; López-García, JC; Rodríguez-Moreno, A1
Baraldi, M; De Micheli, C; De Sarro, A; De Sarro, G; Grasso, S; Micale, N; Puja, G; Zappalà, M1
Kristensen, BW; Noraberg, J; Zimmer, J1
Fedinec, AL; Leffler, CW; Robinson, JS1
Egebjerg, J; Krogsgaard-Larsen, P; Liljefors, T; Nielsen, MM1
O'neill, MF; Ornstein, PL; Osborne, DJ; Sanger, G; Woodhouse, SM1
Bräuner-Osborne, H; Egebjerg, J; Frølund, B; Greenwood, JR; Holm, MM; Krogsgaard-Larsen, P; Madsen, U; Nielsen, B; Stensbøl, TB1
Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U1

Other Studies

15 other study(ies) available for alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

ArticleYear
Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid.
    Journal of medicinal chemistry, 1992, Sep-18, Volume: 35, Issue:19

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain; Ibotenic Acid; Isoxazoles; Rats; Receptors, Amino Acid; Stereoisomerism; Structure-Activity Relationship

1992
Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Cats; Electrophoresis; Ibotenic Acid; In Vitro Techniques; Molecular Conformation; Neurons; Oxazoles; Quantum Theory; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Structure-Activity Relationship; Synaptic Membranes

1985
AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
    Journal of medicinal chemistry, 1997, Feb-14, Volume: 40, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Glutamic Acid; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Thiazoles

1997
Schedule-controlled behavioral effects of the selective 2-amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic acid antagonist LY293558 in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Columbidae; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoquinolines; Isoxazoles; Male; N-Methylaspartate; Propionates; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Stereoisomerism; Tetrazoles

1995
Differentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity.
    European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Convulsants; Cues; Discrimination Learning; Discrimination, Psychological; Excitatory Amino Acid Agonists; Isoxazoles; Ligands; Male; Mice; N-Methylaspartate; Propionates; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures

1995
Pharmacological profile of the isomers of the GluR-specific agonist ATPA.
    Canadian journal of physiology and pharmacology, 1998, Volume: 76, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoxazoles; Kynurenic Acid; Propionates; Quinoxalines; Rats; Receptors, Glutamate; Stereoisomerism

1998
GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jan-01, Volume: 20, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Gene Expression; GluK2 Kainate Receptor; Glutamic Acid; Hippocampus; Ion Channel Gating; Isoxazoles; Kainic Acid; Neurons; Propionates; Protein Structure, Tertiary; Rats; Receptors, Kainic Acid; RNA, Messenger; Structure-Activity Relationship

2000
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-01, Volume: 97, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella

2000
Synthesis and anticonvulsant activity of novel and potent 6,7-methylenedioxyphthalazin-1(2H)-ones.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cells, Cultured; Convulsants; Drug Evaluation, Preclinical; Electroshock; Excitatory Amino Acid Agonists; Isoxazoles; Kainic Acid; Mice; Mice, Inbred DBA; Neurons; Patch-Clamp Techniques; Pentylenetetrazole; Phthalazines; Propionates; Receptors, AMPA; Receptors, Kainic Acid; Seizures; Structure-Activity Relationship

2000
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
    Brain research, 2001, Oct-26, Volume: 917, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar

2001
Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Arterioles; Carbon Monoxide; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heme Oxygenase (Decyclizing); Isoxazoles; Mesoporphyrins; Metalloporphyrins; Propionates; Protoporphyrins; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Swine; Vasodilation

2002
The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741.
    Molecular pharmacology, 2003, Volume: 63, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Isoxazoles; Models, Molecular; Mutagenesis; Propionates; Receptors, AMPA; Receptors, Kainic Acid; Serine; Xenopus laevis

2003
Locomotor activity detects subunit-selective effects of agonists and decahydroisoquinoline antagonists at AMPA/kainic acid ionotropic glutamate receptors in adult rats.
    Psychopharmacology, 2005, Volume: 179, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoquinolines; Isoxazoles; Kainic Acid; Male; Motor Activity; Propionates; Rats; Receptors, AMPA; Receptors, Kainic Acid

2005
Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology.
    Bioorganic & medicinal chemistry, 2005, Sep-15, Volume: 13, Issue:18

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Computer Simulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoxazoles; Models, Molecular; Oocytes; Patch-Clamp Techniques; Propionates; Rats; Receptors, Glutamate; Xenopus laevis

2005
Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glycine; Hydrogen Bonding; Isoxazoles; Ligands; Molecular Conformation; Molecular Structure; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship; Thermodynamics

1994