alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and substance p

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with substance p in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's20 (68.97)18.2507
2000's7 (24.14)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Randic, M; Rusin, KI; Ryu, PD1
Malmberg, AB; Yaksh, TL1
Budai, D; Larson, AA; Wilcox, GL1
Hećimović, H; Randić, M; Ryu, PD1
Beal, MF; Ferrante, RJ; Kowall, NW; Swartz, KJ1
Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N1
Murase, K; Randic, M; Ryu, PD1
Kuraishi, Y; Okano, K; Satoh, M1
Hamada, T; Shibata, S; Watanabe, A; Watanabe, S1
Björkman, R; Hallman, KM; Hedner, J; Hedner, T; Henning, M2
Chizh, BA; Cumberbatch, MJ; Headley, PM1
Cerne, R; Jiang, MC; Kolaj, M; Randic, M; Rusin, KI1
Neugebauer, V; Rumenapp, P; Schaible, HG1
Beckstead, RM1
Bunnett, NW; Grady, EF; Martínez, V; Marvizón, JC; Mayer, EA1
Baamonde, A; Hidalgo, A; Menéndez, L1
Emmerson, PJ; Kinney, GA; Miller, RJ1
Long, LO; Mokha, SS; Wang, XM; Zhang, KM1
Henry, JL; Pitcher, GM1
Arcaya, JL; Cano, G; Cuesta, MC; Maixner, W; Sanchez, L; Suarez-Roca, H1
Bago, M; Cowan, AR; Dean, C; Seagard, JL1
Alvarez-Vega, M; Baamonde, A; Hidalgo, A; Menéndez, L1
Chung, SS; Gwak, YS; Kim, YS; Lee, EH; Leem, JW; Nam, TS1
Ehrenberger, K; Felix, D; Felix, H; Oestreicher, E1
Baude, A; Blondeau, C; Colin, I1
Cahill, CM; Henry, JL; Ménard, HA; Ribeiro-da-Silva, A; Sharif Naeini, R1
Aoki, J; Inoue, M; Ma, L; Ueda, H1
Ikeda, T; Nakayama, T; Naono, R; Nishimori, T1

Other Studies

29 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and substance p

ArticleYear
Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins.
    Journal of neurophysiology, 1992, Volume: 68, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Cesium; Colforsin; Glycine; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Peptides; Phorbol Esters; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Tachykinins

1992
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
    Science (New York, N.Y.), 1992, Aug-28, Volume: 257, Issue:5074

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P

1992
Modulation of N-methyl-D-aspartate and (R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) responses of spinal nociceptive neurons by a N-terminal fragment of substance P.
    European journal of pharmacology, 1992, Jun-17, Volume: 216, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Ibotenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

1992
Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones.
    Neuroscience letters, 1990, Sep-04, Volume: 117, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P

1990
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Biogenic Amines; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Huntington Disease; Ibotenic Acid; Kainic Acid; Male; Mesencephalon; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Substance P

1991
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists.
    Neuroscience letters, 1991, Nov-25, Volume: 133, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P

1991
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
    Neuroscience letters, 1989, Aug-14, Volume: 103, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P

1989
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:9

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P

1993
Protein-synthesis inhibitor blocks (R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-or substance P-induced phase shift of the circadian rhythm of neuronal activity in the rat suprachiasmatic nucleus in vitro.
    Neuroscience letters, 1994, Feb-28, Volume: 168, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aplysia; Circadian Rhythm; Cycloheximide; In Vitro Techniques; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; Substance P; Suprachiasmatic Nucleus

1994
Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P.
    Pain, 1994, Volume: 57, Issue:3

    Topics: Acetaminophen; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Substance P

1994
Modulation of excitatory amino acid responses by tachykinins and selective tachykinin receptor agonists in the rat spinal cord.
    British journal of pharmacology, 1995, Volume: 115, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acids; Male; N-Methylaspartate; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Tachykinin; Spinal Cord; Substance P; Tachykinins

1995
Interactions between excitatory amino acids and tachykinins and long-term changes of synaptic responses in the rat spinal dorsal horn.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Rats; Spinal Cord; Substance P; Synapses; Tetrodotoxin

1993
The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat.
    The European journal of neuroscience, 1996, Volume: 8, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Benzamides; Carrageenan; Hyperalgesia; Iontophoresis; Kaolin; Knee Joint; Male; Neurokinin A; Nociceptors; Pain; Piperidines; Pressure; Rats; Rats, Wistar; Receptors, Neurokinin-2; Spinal Cord; Substance P

1996
N-methyl-D-aspartate acutely increases proenkephalin mRNA in the rat striatum.
    Synapse (New York, N.Y.), 1995, Volume: 21, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; Histocytochemistry; In Situ Hybridization; Injections, Intraventricular; Male; N-Methylaspartate; Prosencephalon; Protein Precursors; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P

1995
Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:12 Suppl

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Diclofenac; Ibuprofen; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substance P

1996
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P

1997
Spinal calmodulin inhibitors reduce N-methyl-D-aspartate- and septide-induced nociceptive behavior.
    European journal of pharmacology, 1997, Sep-17, Volume: 335, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Enzyme Inhibitors; Imidazoles; Injections, Intraventricular; Male; N-Methylaspartate; Neurokinin A; Pain; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Spinal Cord; Substance P; Sulfonamides

1997
Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, May-15, Volume: 18, Issue:10

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arcuate Nucleus of Hypothalamus; Complement C7; Excitatory Amino Acid Agonists; Female; Galanin; Glutamic Acid; GTP-Binding Proteins; Male; Neural Inhibition; Neuropeptides; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Spider Venoms; Substance P; Synaptic Transmission

1998
Orphanin FQ (nociceptin) modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli, and blocks the substance P-induced facilitation of N-methyl-D-aspartate-evoked responses.
    Neuroscience, 1999, Volume: 93, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Injections, Intraventricular; Iontophoresis; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurons; Nociceptin; Opioid Peptides; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatosensory Cortex; Substance P; Trigeminal Nerve

1999
Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo.
    Neuroscience, 1999, Volume: 93, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Signaling; Cyclooxygenase Inhibitors; Eicosanoids; Excitatory Amino Acid Agonists; Glutamic Acid; Indomethacin; Iontophoresis; Male; N-Methylaspartate; Neurons, Afferent; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Substance P

1999
Opposite modulation of capsaicin-evoked substance P release by glutamate receptors.
    Neurochemistry international, 1999, Volume: 35, Issue:6

    Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Nociceptors; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei

1999
Potentiation of non-N-methyl-D-aspartate receptor-induced changes in blood pressure by substance P in rats.
    Neuroscience letters, 2000, Jan-14, Volume: 278, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Drug Synergism; Heart Rate; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Substance P

2000
Effects of the calcium release inhibitor dantrolene and the Ca2+-ATPase inhibitor thapsigargin on spinal nociception in rats.
    Pharmacology, 2001, Volume: 62, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Behavior, Animal; Calcium; Calcium-Transporting ATPases; Dantrolene; Enzyme Inhibitors; Male; Muscle Relaxants, Central; N-Methylaspartate; Pain; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Spinal Cord; Substance P; Thapsigargin

2001
Effects of iontophoretically applied substance P, calcitonin gene-related peptide on excitability of dorsal horn neurones in rats.
    Yonsei medical journal, 2001, Volume: 42, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcitonin Gene-Related Peptide; Excitatory Amino Acid Agonists; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2001
Role of substance P in the peripheral vestibular and auditory system.
    Advances in oto-rhino-laryngology, 2002, Volume: 59

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Auditory Cortex; Cochlea; Hair Cells, Auditory, Inner; Humans; N-Methylaspartate; Substance P; Vestibular Nerve; Vestibule, Labyrinth

2002
Neurokinin release in the rat nucleus of the solitary tract via NMDA and AMPA receptors.
    Neuroscience, 2002, Volume: 115, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurokinin A; Neurokinin B; Presynaptic Terminals; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Solitary Nucleus; Substance P; Synaptic Transmission; Vagus Nerve; Visceral Afferents

2002
Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis.
    The European journal of neuroscience, 2005, Volume: 22, Issue:8

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Freund's Adjuvant; Functional Laterality; Immunohistochemistry; Iontophoresis; Male; Microscopy, Immunoelectron; N-Methylaspartate; Neuronal Plasticity; Neurons; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Time Factors

2005
Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain.
    Journal of neurochemistry, 2008, Volume: 107, Issue:6

    Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; In Vitro Techniques; Lysophosphatidylcholines; Lysophospholipids; Mice; Multienzyme Complexes; N-Methylaspartate; Phosphodiesterase I; Phospholipases A2; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Signal Transduction; Spinal Cord; Substance P

2008
NMDA and AMPA receptors contribute to the maintenance of substance P-induced thermal hyperalgesia.
    Neuroscience research, 2010, Volume: 67, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P

2010