alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with quisqualic acid in 194 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (19.07) | 18.7374 |
| 1990's | 142 (73.20) | 18.2507 |
| 2000's | 14 (7.22) | 29.6817 |
| 2010's | 1 (0.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armstrong, N; Gouaux, E; Mayer, M | 1 |
| Barinka, C; Hlouchová, K; Konvalinka, J; Lubkowski, J; Majer, P; Mlcochová, P; Plechanovová, A; Rovenská, M; Slusher, BS; Tsukamoto, T | 1 |
| Bräuner-Osborne, H; Brehm, L; Christensen, IT; Didriksen, M; Ebert, B; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U; Søby, KK | 1 |
| Bloms, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Beninger, RJ; Boegman, RJ; Cockhill, J; Jhamandas, K | 1 |
| Gottmann, K; Lessmann, V; Lux, HD | 1 |
| Bloms, P; Madeja, M; Müsch-Nittel, K; Musshoff, U; Speckmann, EJ | 1 |
| Maruyama, M; Nakazawa, M; Takeda, K | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Garrone, B; Pittaluga, A; Raiteri, M | 1 |
| Clark, B; Mobbs, P | 1 |
| Andersen, CF; Frandsen, A; Schousboe, A | 1 |
| Fain, GL; Yazejian, B | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Kawai, N; Nakajima, T; Robinson, HP; Shimazaki, K; Takenawa, T | 1 |
| Balázs, R; Hack, N; Kumar, KN; Michaelis, E; Resink, A; Van der Valk, JB | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 2 |
| Mishina, M; Nagahari, K; Sakimura, K; Uchino, S | 1 |
| Cai, NS; Erdö, SL | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Randic, M; Rusin, KI; Ryu, PD | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 2 |
| Davies, JA; Dickie, BG; Lewis, MJ | 1 |
| Gale, K; Miller, LP; Murray, TF; Zhong, P | 1 |
| Baird, JG; Challiss, RA; Nahorski, SR | 1 |
| Giacobini, E; Matsuoka, Y; Rakonczay, Z | 1 |
| Courtney, MJ; Nicholls, DG | 1 |
| Jones, MG; Lodge, D; Palmer, AJ | 1 |
| Blazynski, C; Linn, DM; Massey, SC; Redburn, DA | 1 |
| Gallo, V; Levi, G; Patrizio, M | 2 |
| Mayer, ML; Patneau, DK | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Gannon, RL; Terrian, DM | 1 |
| MacVicar, BA; Tse, FW; Weiss, S | 1 |
| Chang, YC; Lee, YH; Leng, CH; Lin, YH | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Hu, GY; Storm, JF | 1 |
| Cai, NS; Erdö, SL; Kiss, B | 1 |
| Hećimović, H; Randić, M; Ryu, PD | 1 |
| Mayer, ML | 1 |
| Audinat, E; Crepel, F; Geoffroy, M; Hamon, B; Kado, RT; Lambolez, B; Rossier, J | 1 |
| Connor, JA; Linden, DJ | 1 |
| Amaya, Y; Hattori, S; Kawamoto, S; Mishina, M; Miyagi, Y; Okuda, K; Onishi, H | 1 |
| Franke, C; Hatt, H; Rosenheimer, JL; Smith, DO; Zufall, F | 1 |
| Leander, JD; Ornstein, PL; Salhoff, CR; Schoepp, DD | 1 |
| Larson, J; Lynch, G | 1 |
| Bowie, D; Smart, TG | 1 |
| Ferriero, DM; Simon, RP | 1 |
| Ito, M; Karachot, L | 2 |
| Cha, JH; Drejer, J; Honoré, T; Nielsen, EO; Young, AB | 1 |
| Glaum, SR; Holzwarth, JA; Miller, RJ | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA | 1 |
| Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H | 1 |
| Dawson, TL; Dingledine, R; Nicholas, RA | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Bockaert, J; Charpentier, N; Dumuis, A; Pin, JP; Sebben, M | 1 |
| Boos, R; Müller, F; Wässle, H | 1 |
| Thomson, AM | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Anis, NA; Jones, MG; Lodge, D | 1 |
| Anderson, MC; Chung, EY; Van Woert, MH | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Crawford, RD; Johnson, DD; Pedder, SC; Tuchek, JM; Wilcox, RI | 1 |
| Herb, A; Keinänen, K; Sakmann, B; Seeburg, PH; Sommer, B; Verdoorn, TA; Werner, P; Wisden, W | 1 |
| Charpak, S; Do, KQ; Gähwiler, BH; Knöpfel, T | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Choi, DW; Goldberg, MP; Hartley, DM; Koh, JY | 1 |
| Yang, J; Zorumski, CF | 1 |
| Bockaert, J; Lory, P; Nargeot, J; Pin, JP; Rassendren, FA | 1 |
| Christensen, BN; O'Dell, TJ | 2 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Bridges, RJ; Cotman, CW; Kadri, M; Kahle, JS; Nunn, PB; Stevens, DR | 1 |
| Ross, SM; Roy, DN; Spencer, PS | 1 |
| Weiss, S | 1 |
| Cotman, CW; Monaghan, DT; Palmer, E | 2 |
| Baudry, M; Nakagawa, Y | 1 |
| Ito, I; Sugiyama, H; Taji, H; Watanabe, M; Yamamoto, Y | 1 |
| O'Dell, TJ | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Anwyl, R | 1 |
| Aizenman, E; Karschin, A; Lipton, SA | 1 |
| Baraban, JM; Stratton, KR; Worley, PF | 1 |
| Ambrosini, A; Barnard, EA; Henley, JM; Krogsgaard-Larsen, P | 1 |
| Horne, AL; Simmonds, MA | 1 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Cross, A; Skan, W; Slater, P | 1 |
| Choi, DW; Koh, J; Peters, S | 1 |
| Morgan, IG | 1 |
| Murphy, DE; Snowhill, EW; Williams, M | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Benavides, J; Carter, C; Fage, D; Scatton, B | 1 |
| Fischbach, GD; Thio, LL; Trussell, LO; Zorumski, CF | 2 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Errami, M; Nieoullon, A | 1 |
| Blake, JF; Brown, MW; Collingridge, GL | 1 |
| Baudry, M; Kessler, M; Lynch, G; Terramani, T | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| Shreve, PE; Uretsky, NJ | 1 |
| Miller, RJ; Murphy, SN | 1 |
| Massey, SC; Miller, RF | 1 |
| Kerkut, GA; Mat Jais, AM; Walker, RJ | 1 |
| Thal, LJ; Winkler, J | 1 |
| Lerma, J; Mellström, B; Naranjo, JR; Paternain, AV | 1 |
| MacDermott, AB; Reichling, DB | 1 |
| Connor, JA; Linden, DJ; Smeyne, M | 1 |
| Fox, EA; Gruol, DL | 1 |
| Glowinski, J; Prémont, J; Stella, N; Tencé, M | 1 |
| Lees, GJ; Leong, W | 1 |
| Klitgaard, H; Laudrup, P | 1 |
| Everitt, BJ; Marston, HM; Robbins, TW; West, HL; Wilkinson, LS | 1 |
| Cull-Candy, SG; Wyllie, DJ | 1 |
| Dev, KK; Morris, BJ | 1 |
| Hatt, H; Kruse, M; Schmidt, KF | 1 |
| Amico, C; Condorelli, DF; Dell'Albani, P; Giuffrida-Stella, AM; Kaczmarek, L; Lukasiuk, K | 1 |
| Akopian, A; Krizaj, D; Witkovsky, P | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Dekermendjian, K; Frandsen, A; Nielsen, M; Schousboe, A; Witt, MR | 1 |
| Herrero, JF | 1 |
| Bettler, B; Hartley, M; Heinemann, SF; O'Hara, PJ; Sheppard, PO; Stern-Bach, Y | 1 |
| Madamba, SG; Nie, Z; Siggins, GR | 1 |
| Balázs, R; Hack, N | 1 |
| Chen, AD; Thal, LJ; Waite, JJ; Wardlow, ML | 1 |
| Oja, SS; Saransaari, P | 2 |
| Carvalho, AP; Carvalho, CM; Duarte, CB; Ferreira, IL; Santos, PF | 1 |
| Bloms-Funke, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Dowling, JE; Grant, GB | 1 |
| Bendahan, G; Bjelke, B; Boatell, ML; Fuxe, K; Mahy, N; Olson, L; Tinner, B | 1 |
| Acciarri, N; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Ferraro, L; Morari, M; Piazza, G | 1 |
| Park, J; Tasker, RC; Vornov, JJ | 1 |
| Henley, JM | 1 |
| Herrling, PL; Meier, CL | 1 |
| Matute, C; Miledi, R | 1 |
| Catania, MV; Hollingsworth, Z; Penney, JB; Young, AB | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Everitt, BJ; Page, KJ; Saha, A | 1 |
| Banker, G; Blackstone, CD; Craig, AM; Huganir, RL | 1 |
| Honoré, T; Sheardown, MJ; Suzdak, PD | 1 |
| Casabona, G; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 1 |
| Mayer, ML; Patneau, DK; Vyklicky, L | 1 |
| Schultz, K; Weiler, R | 1 |
| Turner, JP | 1 |
| Dykstra, CL; Gebhart, GF; Meller, ST | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Lehmann, JC; Procureur, D; Wood, PL | 1 |
| Buchwald, NA; Cepeda, C; Levine, MS | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Francois-Bellan, AM; Giraud, P; Hery, F; Hery, M | 1 |
| Baraban, JM; Fiore, RS; Murphy, TH; Pelech, SL; Sanghera, JS | 1 |
| Barnes, S; Mahmud, F; Merchant, V | 1 |
| Bleakman, D; Leander, JD; Lodge, D; Ornstein, PL; Palmer, AJ; Salhoff, CR; Schoepp, DD; Tizzano, JP; Wright, RA | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Friedemann, MN; Gerhardt, GA | 1 |
| Aneiros, A; Flores, A; Garateix, A; García-Andrade, JM; Palmero, A; Soto, E; Vega, R | 1 |
| Feltz, P; Jo, YH; Poisbeau, P; Schlichter, R | 1 |
| Bulloch, AG; Lukowiak, K; Magoski, NS; McKenney, KK; Nesic, OB; Syed, NI | 1 |
| Acuña, C; Cudeiro, J; Martinez-Conde, S; Rivadulla, C; Rodriguez, R | 1 |
| Egyed, A; Kovács, AD | 1 |
| Folbergrová, J; Haugvicová, R; Lisý, V; Stastný, F | 1 |
| Inoue, T; Ito, KI; Kato, H; Mikoshiba, K; Miyakawa, H | 1 |
| Benjamin, PR; Brierley, MJ; Yeoman, MS | 1 |
| Kleinrok, Z; Kocki, T; Saran, T; Turski, WA; Urbanska, EM | 1 |
| Bianchi, L; Della Corte, L; Giovannini, MG; Pepeu, G; Rakovska, A | 1 |
| Solomon, IC | 1 |
| Henry, JL; Pitcher, GM | 1 |
| Johns, RA; Tichotsky, A; Zuo, Z | 1 |
| Cooke, IM; Duan, S | 1 |
| de Almeida, OM; de Mello, FG; de Mello, MC; Gardino, PF; Kubrusly, RC; Loureiro-Dos-Santos, NE; Reis, RA | 1 |
| Figueroa, L; Jaffe, EH | 1 |
| Chiang, AS; Lin, SC; Liu, HP; Pszczolkowski, MA | 1 |
| Lisý, V; Stastný, F | 1 |
| Gouaux, E; Horning, M; Jin, R; Mayer, ML | 1 |
| André, N; Gillardin, JM; Heulard, I; Verleye, M | 1 |
| Palmer, AG; Valentine, ER | 1 |
| Howe, JR; Robert, A; Vogensen, SB; Zhang, W | 1 |
| Hársing, LG; Kovács, AD; Kovács, G; Lévay, G; Szabó, G; Tihanyi, K; Vegh, MG | 1 |
| Agoston, M; Albert, M; Barkóczy, J; Benedek, A; Gacsályi, I; Gigler, G; Hársing, LG; Kapus, G; Kertész, S; Lévay, G; Markó, B; Matucz, E; Móricz, K; Simó, A; Szabó, G; Szénási, G; Vegh, M | 1 |
| Jantas, D; Jaworska-Feil, L; Lason, W; Lipkowski, AW | 1 |
| Dharkar, P; Han, TH; Lee, CH; Li, Y; Mayer, ML; Serpe, M | 1 |
194 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and quisqualic acid
| Article | Year |
|---|---|
Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Substitution; Animals; Crystallography, X-Ray; Excitatory Amino Acid Agonists; Female; Kainic Acid; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Ovary; Protein Conformation; Protein Structure, Secondary; Receptors, AMPA; Recombinant Proteins; Xenopus laevis | 2003 |
Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.
Topics: Crystallography, X-Ray; Glutamate Carboxypeptidase II; Humans; Models, Molecular; Molecular Mimicry; Protein Conformation; Recombinant Proteins | 2007 |
Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid.
Topics: Alanine; Animals; Anticonvulsants; Brain; Calcium Chloride; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoxazoles; Male; Mice; Molecular Conformation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Stereoisomerism | 1998 |
Time course of glutamate receptor expression in individual oocytes of Xenopus laevis after injection of rat brain RNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, Glutamate; RNA, Messenger; Xenopus laevis | 1992 |
Excitotoxic lesions of rat basal forebrain: differential effects on choline acetyltransferase in the cortex and amygdala.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Prosencephalon; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1992 |
Evans blue reduces macroscopic desensitization of non-NMDA receptor mediated currents and prolongs excitatory postsynaptic currents in cultured rat thalamic neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evans Blue; Female; Glutamates; Ibotenic Acid; Ion Channel Gating; Neurons; Pregnancy; Quisqualic Acid; Rats; Receptors, Amino Acid; Synapses; Thalamus | 1992 |
Tunicamycin-induced inhibition of functional expression of glutamate receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ion Channels; Kainic Acid; Oligosaccharides; Oocytes; Quisqualic Acid; Receptors, Glutamate; RNA; Tunicamycin; Xenopus laevis | 1992 |
Evidence that [3H]glutamate binding sites are masked by biologically relevant endogenous factor on cell membranes of frog spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cytosol; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Piperazines; Quisqualic Acid; Rana catesbeiana; Spinal Cord | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. II. Evidence for functional cooperation and for coexistence on the same axon terminal.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dizocilpine Maleate; Drug Interactions; Hippocampus; Ibotenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Transmitter-operated channels in rabbit retinal astrocytes studied in situ by whole-cell patch clamping.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Bicuculline; Chloride Channels; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Membrane Proteins; Quisqualic Acid; Rabbits; Receptors, GABA-A; Retina; Time Factors | 1992 |
Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Pertussis Toxin; Quisqualic Acid; Time Factors; Virulence Factors, Bordetella | 1992 |
Excitatory amino acid receptors on isolated retinal ganglion cells from the goldfish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retinal Ganglion Cells; Sodium | 1992 |
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neu
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dantrolene; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Verapamil | 1992 |
Purification of AMPA type glutamate receptor by a spider toxin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cattle; Cerebellum; Chloride Channels; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Liposomes; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Spider Venoms | 1992 |
NMDA treatment and K(+)-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellar Cortex; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Mutations in a putative agonist binding region of the AMPA-selective glutamate receptor channel.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Glutamates; Ibotenic Acid; Kainic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Recombinant Proteins; Sequence Homology, Nucleic Acid; Xenopus laevis | 1992 |
The effects of kainate and the glutamate agonist, AMPA, are not separable in rat neocortical cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Neurons; Pregnancy; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Cesium; Colforsin; Glycine; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Peptides; Phorbol Esters; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Tachykinins | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
NMDA-induced release of nitric oxide potentiates aspartate overflow from cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Role for ionotropic and metabotropic receptors in quisqualate-stimulated inositol polyphosphate accumulation in rat cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Cycloleucine; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Effects of L-beta-N-methylamino-L-alanine (L-BMAA) on the cortical cholinergic and glutamatergic systems of the rat.
Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Choline O-Acetyltransferase; Cyanobacteria Toxins; Ibotenic Acid; Injections, Intraventricular; Male; Parasympathetic Nervous System; Quinuclidinyl Benzilate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Cycloleucine; Cytoplasm; Ibotenic Acid; Kinetics; N-Methylaspartate; Neurotoxins; Piperidines; Quisqualic Acid; Receptors, Neurotransmitter | 1991 |
Excitatory amino acids: new tools for old stories or pharmacological subtypes of glutamate receptors: electrophysiological studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Stem; Cerebral Cortex; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Wasp Venoms | 1991 |
Acetylcholine release from the rabbit retina mediated by kainate receptors.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Choline; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rabbits; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina | 1991 |
Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Exocytosis; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Taurine | 1991 |
Kinetic analysis of interactions between kainate and AMPA: evidence for activation of a single receptor in mouse hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Mice; Neurons; Quisqualic Acid; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediated.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Cerebellum; Chlorides; Cyclic GMP; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Lithium; Lithium Chloride; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nipecotic Acids; Nitroprusside; Organic Anion Transporters; Proline; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Secretory Rate; Sodium; Stimulation, Chemical | 1991 |
Quisqualate agonists occlude kainate-induced current in cultured striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Drug Interactions; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neurons; Quisqualic Acid | 1991 |
Solubilization, characterization, and partial purification of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-, quisqualate-, kainate-sensitive L-glutamate binding sites from porcine brain synaptic junctions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chromatography; Detergents; Glutamates; Glutamic Acid; Hot Temperature; Ibotenic Acid; Kainic Acid; Octoxynol; Polyethylene Glycols; Quisqualic Acid; Solubility; Synapses | 1991 |
Presynaptic facilitation of dopamine release through D,L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors on synaptosomes from the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dipeptides; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Nerve Endings; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptosomes; Tritium | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Neurons; Phorbol Esters; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Vinpocetine preferentially antagonizes quisqualate/AMPA receptor responses: evidence from release and ligand binding studies.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membranes; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium; Vinca Alkaloids | 1991 |
Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1990 |
Glutamate: three meetings but how many receptors? Excitatory Amino Acids 1990: a Fidia Research Foundation Symposium, Padua, Italy, May 21-26, 1990. Excitatory Amino Acid Receptors in the Brain: Functions and Disorders, Montreal, Canada, June 23-24, 1990.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; GTP-Binding Proteins; Ibotenic Acid; Ion Channel Gating; Ion Channels; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction | 1990 |
Reduction of desensitization of a glutamate ionotropic receptor by antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channels; Membrane Potentials; Oocytes; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1991 |
Participation of postsynaptic PKC in cerebellar long-term depression in culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellum; Enzyme Activation; Ibotenic Acid; In Vitro Techniques; Indoles; Mice; Naphthalenes; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Purkinje Cells; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Synaptic Membranes | 1991 |
Functional expression of the alpha 1 subunit of the AMPA-selective glutamate receptor channel, using a baculovirus system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baculoviridae; DNA, Recombinant; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; Ibotenic Acid; Insecta; Ion Channels; Kainic Acid; Kinetics; Mice; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Transfection | 1991 |
Desensitization and resensitization rates of glutamate-activated channels may regulate motoneuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Chick Embryo; Electrophysiology; Glutamates; Ibotenic Acid; Ion Channels; Kainic Acid; Motor Neurons; Quinoxalines; Quisqualic Acid; Synaptic Transmission | 1991 |
Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
A test of the spine resistance hypothesis for LTP expression.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cold Temperature; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Interaction of 5-bromowillardiine with non-NMDA receptors expressed in Xenopus laevis oocytes injected with chick brain mRNA.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chickens; Female; Ibotenic Acid; Injections; Kainic Acid; Membrane Potentials; Neuromuscular Depolarizing Agents; Oocytes; Quisqualic Acid; Receptors, Dopamine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1991 |
Neonatal striatal NADPH-diaphorase neurons are vulnerable to quisqualate and its analogue alpha-amino-3-hydroxy-5-methyl-4-isoxazole proprionate (AMPA).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Corpus Striatum; Functional Laterality; Ibotenic Acid; NADPH Dehydrogenase; Neurons; Neurotoxins; Quisqualic Acid; Rats; Rats, Inbred Strains; Reference Values | 1991 |
The selective ionotropic-type quisqualate receptor agonist AMPA is a potent neurotoxin in immature rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Corpus Striatum; Ibotenic Acid; Injections; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter | 1990 |
Messengers mediating long-term desensitization in cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cerebellum; Cyclic GMP; Egtazic Acid; Ibotenic Acid; In Vitro Techniques; omega-N-Methylarginine; Perfusion; Pertussis Toxin; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Virulence Factors, Bordetella | 1990 |
Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Oxadiazoles; Oxazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Glutamate receptors activate Ca2+ mobilization and Ca2+ influx into astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Benzofurans; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Fluorescent Dyes; Fura-2; Glutamates; Hippocampus; Ibotenic Acid; Nickel; Nimodipine; Organ Specificity; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium Chloride; Carbachol; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Oxadiazoles; Oxazoles; Potassium Chloride; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1990 |
Homomeric GluR1 excitatory amino acid receptors expressed in Xenopus oocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Ganglia, Spinal; Hippocampus; Ibotenic Acid; Kainic Acid; Membrane Proteins; Oocytes; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
On concanavalin A-treated striatal neurons quisqualate clearly behaves as a partial agonist of a receptor fully activated by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Concanavalin A; Corpus Striatum; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Mice; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Veratridine | 1990 |
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Cats; Electrodes; Glutamates; Glutamic Acid; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Retinal Ganglion Cells | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Philanthotoxin blocks quisqualate-, AMPA- and kainate-, but not NMDA-, induced excitation of rat brainstem neurones in vivo.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Female; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quisqualic Acid; Rats; Rats, Inbred Strains; Wasp Venoms | 1990 |
The effects of inferior olive lesion on strychnine seizure.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Dizocilpine Maleate; Epilepsies, Myoclonic; Glutamates; Ibotenic Acid; Male; Olivary Nucleus; Pyridines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures; Strychnine; Tritium | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
Quisqualate receptors in epileptic fowl: the absence of coupling between quisqualate and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Brain; Chickens; Convulsants; Dose-Response Relationship, Drug; Epilepsy; Ibotenic Acid; Kinetics; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
A family of AMPA-selective glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Base Sequence; Brain; Glutamates; Ibotenic Acid; Kainic Acid; Kinetics; Molecular Sequence Data; Multigene Family; Oligonucleotide Probes; Organ Specificity; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Sequence Homology, Nucleic Acid | 1990 |
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electric Conductivity; Electrophysiology; Hippocampus; Ibotenic Acid; Kynurenic Acid; Neurons; Potassium Channels; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Muscarinic; Receptors, Neurotransmitter | 1990 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of cerebellar granule cells in culture: effect of kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Dizocilpine Maleate; DNA; Electric Stimulation; Glutamine; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Receptor subtypes involved in, and time course of, the long-term desensitization of glutamate receptors in cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Non-NMDA receptor-mediated neurotoxicity in cortical culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Drug Synergism; Ibotenic Acid; Kainic Acid; Microscopy, Phase-Contrast; Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Time Factors; Zinc | 1990 |
AMPA, kainate, and quisqualate activate a common receptor-channel complex on embryonic chick motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Binding, Competitive; Chick Embryo; Ibotenic Acid; Ion Channels; Kainic Acid; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Receptors, Cell Surface | 1988 |
A specific quisqualate agonist inhibits kainate responses induced in Xenopus oocytes injected with rat brain RNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Convulsants; Female; Ibotenic Acid; Kainic Acid; Kinetics; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA; Xenopus laevis | 1989 |
Horizontal cells isolated from catfish retina contain two types of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Cations, Divalent; Cell Membrane Permeability; Cells, Cultured; Concanavalin A; Convulsants; Glutamates; Ibotenic Acid; Ictaluridae; Ion Channels; Kainic Acid; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Valine; Zinc | 1989 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that beta-L-ODAP is a selective non-NMDA agonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Electrophysiology; Ibotenic Acid; Kainic Acid; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship; Synaptic Membranes | 1989 |
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates | 1989 |
Two distinct quisqualate receptor systems are present on striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Ibotenic Acid; Inositol Phosphates; Mice; Oxadiazoles; Oxazoles; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter | 1989 |
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Dissociation between changes in glutamate receptor binding sites and their coupling to phosphatidylinositol metabolism following intrahippocampal colchicine injection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Colchicine; Hippocampus; Ibotenic Acid; Male; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Second Messenger Systems | 1989 |
Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chickens; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1989 |
A voltage-clamp study of isolated stingray horizontal cell non-NMDA excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Separation; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fishes; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Early warning for LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Synapses; Time Factors | 1989 |
Two pharmacological classes of quisqualate-induced electrical responses in rat retinal ganglion cells in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Retina; Retinal Ganglion Cells | 1989 |
Excitation of hippocampal neurons by stimulation of glutamate Qp receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electric Stimulation; Electrophysiology; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Muscarinic; Receptors, Neurotransmitter | 1989 |
Evidence for a single glutamate receptor of the ionotropic kainate/quisqualate type.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Protein Conformation; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Xenopus laevis | 1989 |
The pharmacology of quisqualate and AMPA in the cerebral cortex of the rat in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Neuromuscular Depolarizing Agents; Oxadiazoles; Oxazoles; Pentobarbital; Quisqualic Acid; Rats; Rats, Inbred Strains; Taurine | 1989 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
Binding sites for [3H]glutamate and [3H]aspartate in human cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aspartic Acid; Binding Sites; Calcium Chloride; Cerebellum; Dicarboxylic Acids; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Oxadiazoles; Quisqualic Acid | 1986 |
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc | 1987 |
AMPA is a powerful neurotoxin in the chicken retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chickens; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Ibotenic Acid; Injections; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Oxadiazoles; Oxazoles; Quisqualic Acid; Retina; Retinal Ganglion Cells; Vitreous Body | 1987 |
Characterization of quisqualate recognition sites in rat brain tissue using DL-[3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) and a filtration assay.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chemical Phenomena; Chemistry; Filtration; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Thiocyanates | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
alpha-[3H]Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding to rat striatal membranes: effects of selective brain lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Denervation; Dopamine; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Ibotenic Acid; Membranes; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; Hippocampus; Ibotenic Acid; Kainic Acid; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1988 |
Effects of thiol-reagents on [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding to rat telencephalic membranes.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Sulfhydryl Reagents; Telencephalon | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Glutamates; Glutamine; Ibotenic Acid; Injections; Kainic Acid; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1988 |
A glutamate receptor regulates Ca2+ mobilization in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Embryo, Mammalian; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Mice; Mice, Inbred C57BL; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Lithium; Lithium Chloride; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1988 |
Glutamate receptors of ganglion cells in the rabbit retina: evidence for glutamate as a bipolar cell transmitter.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Light; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells | 1988 |
The ionic mechanisms associated with the excitatory response of kainate, L-glutamate, quisqualate, ibotenate, AMPA and methyltetrahydrofolate on leech Retzius cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Ganglia; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Leeches; Membrane Potentials; Neurons; Osmolar Concentration; Oxadiazoles; Oxazoles; Pyrrolidines; Quisqualic Acid; Sodium; Tetrahydrofolates | 1984 |
Effects of nerve growth factor treatment on rats with lesions of the nucleus basalis magnocellularis produced by ibotenic acid, quisqualic acid, and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Ibotenic Acid; Immunohistochemistry; Male; Maze Learning; Nerve Growth Factors; Quisqualic Acid; Rats; Rats, Inbred F344; Substantia Innominata; Time Factors | 1995 |
Functional kainate-selective glutamate receptors in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Embryo, Mammalian; Hippocampus; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Female; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Lanthanum; N-Methylaspartate; Neurons; Neurotoxins; Photometry; Potassium; Pregnancy; Presynaptic Terminals; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Induction of cerebellar long-term depression in culture requires postsynaptic action of sodium ions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Electrophysiology; Embryo, Mammalian; Evoked Potentials; Mice; N-Methylaspartate; Neuronal Plasticity; Neurons; Neurotoxins; Picrotoxin; Quisqualic Acid; Receptors, AMPA; Sodium; Synapses; Tetrodotoxin; Veratridine | 1993 |
Ionotropic and metabotropic components of electrophysiological response of cerebellar Purkinje neurons to excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Neurotoxins; Purkinje Cells; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate | 1993 |
Glutamate-evoked release of arachidonic acid from mouse brain astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurotoxins; Organ Specificity; Quisqualic Acid; Receptors, Glutamate; Time Factors; Tritium | 1994 |
Differential effects of NBQX on the distal and local toxicity of glutamate agonists administered intra-hippocampally.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Diazepam; Hippocampus; Injections; Kainic Acid; Limbic System; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate | 1993 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Effects of excitotoxic lesions of the septum and vertical limb nucleus of the diagonal band of Broca on conditional visual discrimination: relationship between performance and choline acetyltransferase activity in the cingulate cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biogenic Amines; Choline O-Acetyltransferase; Conditioning, Operant; Discrimination, Psychological; Dopamine; Frontal Lobe; Gyrus Cinguli; Hydroxyindoleacetic Acid; Male; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Stereotaxic Techniques; Visual Perception | 1994 |
A comparison of non-NMDA receptor channels in type-2 astrocytes and granule cells from rat cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cerebellum; Concanavalin A; Cytoplasmic Granules; Electrophysiology; In Vitro Techniques; Ion Channels; Kainic Acid; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1994 |
Modulation of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding sites by nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cerebellum; Cerebral Cortex; Cyclic GMP; Hippocampus; Male; Nitric Oxide; Nitroprusside; Penicillamine; Prosencephalon; Quisqualic Acid; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Tritium | 1994 |
Dopamine alters glutamate receptor desensitization in retinal horizontal cells of the perch (Perca fluviatilis).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Dopamine; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Perches; Pyrrolidinones; Quisqualic Acid; Receptors, Glutamate; Retina; Time Factors | 1994 |
Glutamate receptor-driven activation of transcription factors in primary neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Base Sequence; Binding Sites; Cell Nucleus; Cell Survival; Cells, Cultured; Cycloleucine; Embryo, Mammalian; Gene Expression; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Mice; Molecular Sequence Data; N-Methylaspartate; Neurons; Proto-Oncogene Proteins; Proto-Oncogenes; Quisqualic Acid; Rats; Receptors, Glutamate; Transcription Factors | 1994 |
The effects of L-glutamate, AMPA, quisqualate, and kainate on retinal horizontal cells depend on adaptational state: implications for rod-cone interactions.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adaptation, Physiological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Light; Male; Quinoxalines; Quisqualic Acid; Retina; Retinal Rod Photoreceptor Cells; Xenopus laevis | 1994 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Fetus; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Potassium Chloride; Quisqualic Acid | 1994 |
GABAergic activity of quisqualamine and homoquisqualamine in hemisected spinal cord in vitro preparation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Bicuculline; Decarboxylation; Evoked Potentials; GABA Agonists; Magnesium; Muscimol; Picrotoxin; Quisqualic Acid; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1994 |
Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Carrier Proteins; Computer Simulation; Electrophysiology; Glutamates; HeLa Cells; Humans; In Vitro Techniques; Kainic Acid; Ligands; Models, Molecular; Molecular Sequence Data; Oocytes; Quisqualic Acid; Receptors, Glutamate; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection; Xenopus laevis | 1994 |
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ethanol; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Naloxone; Nucleus Accumbens; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 1994 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of granule cells in culture: effect of quisqualate and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Neurons; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate | 1994 |
Behavioral and biochemical consequences of combined lesions of the medial septum/diagonal band and nucleus basalis in the rat when ibotenic acid, quisqualic acid, and AMPA are used.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Choline O-Acetyltransferase; Frontal Lobe; Ibotenic Acid; Male; Maze Learning; Neurotoxins; Prosencephalon; Quisqualic Acid; Rats; Rats, Inbred F344; Septum Pellucidum | 1994 |
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles | 1994 |
Taurine release from mouse hippocampal slices: effects of glutamatergic substances and hypoxia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Nitrogen; Oxygen; Potassium; Quisqualic Acid; Taurine | 1994 |
Release of [3H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca2+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Nicotinic Acids; Nipecotic Acids; Oximes; Quisqualic Acid; Retina; Tritium | 1994 |
Effects of the epileptogenic agent strychnine on membrane currents elicited by agonists of the NMDA and non-NMDA receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Glycine; Ion Channels; Kainic Acid; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Xenopus laevis | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Differential brain area vulnerability to long-term subcortical excitotoxic lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Damage, Chronic; Calcium; Immunohistochemistry; Male; Nerve Degeneration; Neurotoxins; Prosencephalon; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Septal Nuclei | 1995 |
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcimycin; Cerebral Cortex; Child; Cycloleucine; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Male; Middle Aged; N-Methylaspartate; Phosphatidylinositols; Quisqualic Acid; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrodotoxin | 1995 |
Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/Kainate receptors in organotypic hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Cell Differentiation; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1995 |
Subcellular localization and molecular pharmacology of distinct populations of [3H]-AMPA binding sites in rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Cell Fractionation; Glutamic Acid; Hippocampus; In Vitro Techniques; Isotope Labeling; Kainic Acid; Microscopy, Electron; Microsomes; Neuronal Plasticity; Protein Processing, Post-Translational; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Synaptosomes; Tritium | 1995 |
N-methyl-D-aspartate induces regular firing patterns in the cat lateral habenula in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Ibotenic Acid; Iontophoresis; Kainic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Stereotaxic Techniques; Thalamus | 1993 |
Neurotransmitter receptors and voltage-dependent Ca2+ channels encoded by mRNA from the adult corpus callosum.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antisense Elements (Genetics); Aspartic Acid; Astrocytes; Biomarkers; Calcium Channels; Cattle; Corpus Callosum; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Male; Membrane Potentials; Middle Aged; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA Probes; RNA, Messenger; Xenopus | 1993 |
Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
Differential activation and survival of basal forebrain neurons following infusions of excitatory amino acids: studies with the immediate early gene c-fos.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Survival; Choline O-Acetyltransferase; Corpus Striatum; Genes, fos; Globus Pallidus; Ibotenic Acid; Immunohistochemistry; Male; Neurons; Phosphates; Prosencephalon; Quisqualic Acid; Rats | 1993 |
The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Base Sequence; Cells, Cultured; Embryo, Mammalian; Hippocampus; Ibotenic Acid; Immunohistochemistry; In Situ Hybridization; Macromolecular Substances; Molecular Sequence Data; Neurons; Oligodeoxyribonucleotides; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Synapses | 1993 |
Characterization of the metabotropic glutamate receptor in mouse cerebellar granule cells: lack of effect of 2,3-dihydroxy-6-nitro-7-sulphamoylbenzo(F)-quinoxaline (NBQX).
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Pertussis Toxin; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Virulence Factors, Bordetella | 1993 |
(2s,1'R,2'R,3'R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Ionotropic non-N-methyl-D-aspartate agonists induce retraction of dendritic spinules from retinal horizontal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Carps; Cell Movement; Cyclopentanes; Dendrites; Ibotenic Acid; N-Methylaspartate; Quisqualic Acid; Receptors, Neurotransmitter; Retina | 1993 |
Anion transport blockers inhibit DL-2-amino-4-phosphonobutyrate responses induced by quisqualate in the rat cerebral cortex.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate | 1993 |
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glucagon; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Islets of Langerhans; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Spinal Cord | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Cats; Caudate Nucleus; Dopamine; Ergolines; In Vitro Techniques; N-Methylaspartate; Neostriatum; Quinpirole; Quisqualic Acid; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate, GABA, glycine and taurine modulate serotonin synthesis and release in rostral and caudal rhombencephalic raphe cells in primary cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Neurons; Quinoxalines; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Taurine; Tryptophan | 1993 |
Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Cytosol; Enzyme Activation; Fetus; Molecular Sequence Data; Neurons; Oligopeptides; Phorbol 12,13-Dibutyrate; Picrotoxin; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substrate Specificity; Synapses | 1993 |
Modulation of transmission gain by protons at the photoreceptor output synapse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Aminobutyrates; Animals; Calcium Channels; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Light; Membrane Potentials; Photoreceptor Cells; Protons; Quisqualic Acid; Receptors, Glutamate; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Synapses; Synaptic Transmission | 1993 |
In vitro and in vivo antagonism of AMPA receptor activation by (3S, 4aR, 6R, 8aR)-6-[2-(1(2)H-tetrazole-5-yl) ethyl] decahydroisoquinoline-3-carboxylic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Isoquinolines; Male; Mice; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles; Time Factors | 1995 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
In vivo electrochemical studies of the dynamic effects of locally applied excitatory amino acids in the striatum of the anesthetized rat.
Topics: Adolescent; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Cricetinae; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Humans; Kainic Acid; Male; N-Methylaspartate; Oxidation-Reduction; Potassium; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1996 |
Antagonism of glutamate receptors by a chromatographic fraction from the exudate of the sea anemone Phyllactis flosculifera.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Animals; Chemical Fractionation; Chromatography, Gel; Cnidarian Venoms; Cochlea; Excitatory Amino Acid Antagonists; Iontophoresis; Kainic Acid; Nerve Fibers; Neurons, Afferent; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Sea Anemones; Snails | 1996 |
Electrophysiological characterization of non-NMDA glutamate receptors on cultured intermediate lobe cells of the rat pituitary.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Pituitary Gland; Quisqualic Acid; Rats; Receptors, Glutamate | 1996 |
Glutamate as a putative neurotransmitter in the mollusc, Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Diphosphate; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Nervous System Physiological Phenomena; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Quisqualic Acid; Synapses; Thionucleotides | 1996 |
The influence of nitric oxide on perigeniculate GABAergic cell activity in the anaesthetized cat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Cycloleucine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Geniculate Bodies; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Penicillamine; Photic Stimulation; Quisqualic Acid; S-Nitroso-N-Acetylpenicillamine | 1996 |
Protection against non-NMDA receptor-mediated excitotoxicity by GYKI 52466 in mature telencephalic cultures of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Neurons; Neurotoxins; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Telencephalon | 1996 |
Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: effect of homocysteine-induced seizures.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Reference Values; Seizures; Synaptic Membranes; Tritium | 1997 |
Glutamate-induced hyperpolarization in mouse cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Purkinje Cells; Quisqualic Acid | 1993 |
Glutamate is the transmitter for N2v retraction phase interneurons of the Lymnaea feeding system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Interneurons; Lymnaea; Motor Neurons; Nerve Net; Quisqualic Acid; Synapses | 1997 |
Impairment of brain kynurenic acid production by glutamate metabotropic receptor agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cycloleucine; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sodium | 1997 |
Activation of non-NMDA receptors stimulates acetylcholine and GABA release from dorsal hippocampus: a microdialysis study in the rat.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1998 |
Activation of NMDA and non-NMDA receptors in the caudal ventrolateral medulla dilates the airways.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine Derivatives; Autonomic Nervous System; Bronchoconstriction; Cholinergic Fibers; Dogs; Electric Stimulation; Excitatory Amino Acid Agonists; Female; Kainic Acid; Lung; Male; Medulla Oblongata; Muscle, Smooth; N-Methylaspartate; Parasympatholytics; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 1998 |
Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Signaling; Cyclooxygenase Inhibitors; Eicosanoids; Excitatory Amino Acid Agonists; Glutamic Acid; Indomethacin; Iontophoresis; Male; N-Methylaspartate; Neurons, Afferent; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Substance P | 1999 |
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Halothane; Isoflurane; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction | 1999 |
Glutamate and GABA activate different receptors and Cl(-) conductances in crab peptide-secretory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brachyura; Cells, Cultured; Chloride Channels; Chlorides; Concanavalin A; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quisqualic Acid; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate | 2000 |
Inhibition of choline acetyltransferase by excitatory amino acids as a possible mechanism for cholinergic dysfunction in the central nervous system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Neurons; NG-Nitroarginine Methyl Ester; Propionates; Quisqualic Acid; Retina; Signal Transduction; Tetrodotoxin; Trifluoperazine; Verapamil | 2001 |
Glutamate receptor desensitization block potentiates the stimulated GABA release through external Ca2+-independent mechanisms from granule cells of olfactory bulb.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kinetics; Male; N-Methylaspartate; Neurons; Olfactory Bulb; Potassium Chloride; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2001 |
Ionotropic glutamate receptors mediate juvenile hormone synthesis in the cockroach, Diploptera punctata.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cockroaches; Corpora Allata; Cycloleucine; Cytosol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Juvenile Hormones; Kainic Acid; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 2002 |
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Molsidomine; N-Methylaspartate; Nerve Degeneration; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Wistar; Tritium | 2002 |
Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Crystallography, X-Ray; Glutamic Acid; Ion Channel Gating; Ligands; Methionine; Oocytes; Patch-Clamp Techniques; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quisqualic Acid; Rats; Receptors, AMPA; Solvents; Structure-Activity Relationship; Xenopus laevis | 2002 |
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium | 2004 |
Microsecond-to-millisecond conformational dynamics demarcate the GluR2 glutamate receptor bound to agonists glutamate, quisqualate, and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Glutamic Acid; Ligands; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quisqualic Acid; Receptors, AMPA; Thermodynamics | 2005 |
The relationship between agonist potency and AMPA receptor kinetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Ion Channel Gating; Kidney; Kinetics; Membrane Potentials; Models, Biological; Quisqualic Acid; Receptors, AMPA | 2006 |
The new 2,3-benzodiazepine derivative EGIS-8332 inhibits AMPA/kainate ion channels and cell death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cell Death; Cells, Cultured; Excitatory Amino Acid Antagonists; Male; Neurons; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Stereoisomerism; Telencephalon | 2007 |
Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepines; Brain; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gerbillinae; Male; Membrane Potentials; Mice; Mice, Inbred DBA; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Purkinje Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Seizures; Telencephalon; Time Factors | 2007 |
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone | 2009 |
Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Central Nervous System; Crystallography; Drosophila melanogaster; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Ligands; N-Methylaspartate; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 2016 |