alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and quinazolines

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with quinazolines in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's7 (70.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calligaro, DO; Lodge, D; McQuaid, LA; Mitch, CH; O'Malley, PJ; Ornstein, PL; Schoepp, DD; Smith, EC; South, KK; True, RA1
Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G1
Barabás, P; Egyed, O; Kardos, J; Kökösi, J; Kovács, I; Nagy, PI; Nyikos, L; Skuban, N; Szárics , E; Takács-Novák, K; Temesváriné-Major, E1
Johnson, MS; Jouppila, A; Keinanen, K; Lampinen, M; Mottershead, DG; Pentikainen, OT; Settimo, L1
Barabás, P; Kardos, J; Kökösi, J; Kovács, I; LaszTóczi, B; Nagy, PI; Nyikos, L; Skuban, N; Szárics, E; Takácsné, NK1
Choi, JI; Jeong, SW; Yoon, MH1
Iwakura, Y; Jourdi, H; Nagano, T; Namba, H; Nawa, H; Takei, N; Xiong, H1
Li, B; Malinow, R; Mei, L; Woo, RS1
Catarzi, D; Colotta, V; Costagli, C; Filacchioni, G; Galli, A; Lenzi, O; Varano, F1
Bahare, RS; Khan, SA; Malik, S1

Other Studies

10 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and quinazolines

ArticleYear
Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones.
    Journal of medicinal chemistry, 1992, Sep-04, Volume: 35, Issue:18

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glycine; Ibotenic Acid; Male; Quinazolines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship

1992
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium

1998
Quinazolone-alkyl-carboxylic acid derivatives inhibit transmembrane Ca(2+) ion flux to (+)-(S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Channels; Cell Membrane; Cerebral Cortex; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Ligands; Male; Models, Molecular; Molecular Structure; Piperidines; Propionates; Quinazolines; Rats; Rats, Wistar; Receptors, AMPA; Structure-Activity Relationship

2001
Discrimination between agonists and antagonists by the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid-selective glutamate receptor. A mutation analysis of the ligand-binding domain of GluR-D subunit.
    The Journal of biological chemistry, 2002, Nov-01, Volume: 277, Issue:44

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Baculoviridae; Binding Sites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Ligands; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Quinazolines; Receptors, AMPA; Structure-Activity Relationship

2002
[EFfect of quinazolone-alkyl-carboxylic acid derivatives on the transmembrane Ca2+ ion flux mediated by AMPA receptors].
    Acta pharmaceutica Hungarica, 2002, Volume: 72, Issue:2

    Topics: Alkylation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain Diseases; Calcium; Carboxylic Acids; Cell Membrane; Humans; Quinazolines; Receptors, AMPA

2002
Spinal gabapentin and antinociception: mechanisms of action.
    Journal of Korean medical science, 2003, Volume: 18, Issue:2

    Topics: Acetates; Adrenergic alpha-Antagonists; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amines; Analgesics; Animals; Atropine; Cyclohexanecarboxylic Acids; Dihydroergocristine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Thapsigargin; Triazoles

2003
Transforming growth factor alpha attenuates the functional expression of AMPA receptors in cortical GABAergic neurons.
    Molecular and cellular neurosciences, 2006, Volume: 31, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Electrophysiology; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; gamma-Aminobutyric Acid; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ligands; Neurons; Protein Subunits; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Transforming Growth Factor alpha

2006
The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.
    Neuron, 2007, May-24, Volume: 54, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Drug Interactions; Enzyme Inhibitors; ErbB Receptors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neuregulin-1; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinazolines; Rats; Receptor, ErbB-4; RNA Interference; RNA, Small Interfering; Synapses; Synaptic Transmission; Transfection; Tyrphostins

2007
Novel AMPA and kainate receptor antagonists containing the pyrazolo[1,5-c]quinazoline ring system: Synthesis and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2008, Mar-01, Volume: 16, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Molecular Structure; N-Methylaspartate; Pyrazoles; Quinazolines; Receptors, Kainic Acid; Structure-Activity Relationship

2008
Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: a hybrid pharmacophore approach.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Quinazolines; Rats; Rats, Wistar; Seizures; Thiazoles; Thioamides

2013