alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and piperidines

Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Cycloleucine; Cytoplasm; Ibotenic Acid; Kinetics; N-Methylaspartate; Neurotoxins; Piperidines; Quisqualic Acid; Receptors, Neurotransmitter

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Glycine; Ibotenic Acid; Ion Channels; N-Methylaspartate; Piperidines; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Vasodilator Agents

Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Brain; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Male; N-Methylaspartate; Pipecolic Acids; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Memory; N-Methylaspartate; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gerbillinae; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kinetics; Male; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Depression, Chemical; Electric Stimulation; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Presynaptic; Synaptic Transmission

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Benzamides; Carrageenan; Hyperalgesia; Iontophoresis; Kaolin; Knee Joint; Male; Neurokinin A; Nociceptors; Pain; Piperidines; Pressure; Rats; Rats, Wistar; Receptors, Neurokinin-2; Spinal Cord; Substance P

Topics: Acetylcholine; Adolescent; Adult; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cerebral Cortex; Child; Child, Preschool; Choline O-Acetyltransferase; Excitatory Amino Acid Agonists; Female; Humans; Neuromuscular Depolarizing Agents; Piperidines; Putamen; Rats; Rats, Inbred F344; Rett Syndrome; Thalamus

Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Fluorobenzenes; Hallucinogens; In Vitro Techniques; Interneurons; Lysergic Acid Diethylamide; Male; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium

Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Piperidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Cerebellum; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Membrane Potentials; Piperidines; Purkinje Cells; Pyrrolidinones; Rats; Receptors, AMPA

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain; Dioxoles; Excitatory Amino Acid Agonists; Ion Channels; Memory; Neurons; Nootropic Agents; Piperidines; Pyridines; Pyrrolidinones; Rats; Receptors, AMPA; Subcellular Fractions; Synaptic Membranes; Time Factors

Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Channels; Cell Membrane; Cerebral Cortex; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Ligands; Male; Models, Molecular; Molecular Structure; Piperidines; Propionates; Quinazolines; Rats; Rats, Wistar; Receptors, AMPA; Structure-Activity Relationship

Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Benzoxazines; Cadmium Chloride; Calcium Channel Blockers; Calcium Channels, N-Type; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Organ Culture Techniques; Pertussis Toxin; Piperidines; Presynaptic Terminals; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, GABA-A; Receptors, GABA-B; Rimonabant; Synaptic Transmission; Tetrodotoxin; Virulence Factors, Bordetella

Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Brain Chemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation, Developmental; Humans; Indoles; Kainic Acid; Piperidines; Radioligand Assay; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tritium

Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Female; Hippocampus; Injections, Intravenous; Male; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spinal Cord; Stereotaxic Techniques; Sulfonamides; Thiophenes

Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Mice; Neurons; Piperidines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fluorobenzenes; GABA Antagonists; Glutamic Acid; Hallucinogens; Male; Mice; Mice, Inbred BALB C; Microdialysis; Neurons; Picrotoxin; Piperidines; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sesterterpenes; Tetrodotoxin

Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Corpus Striatum; Cytoprotection; Cytoskeleton; Dioxoles; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; NF-kappa B; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Stimulation, Chemical

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Chlorides; Cyclopropanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Mossy Fibers, Hippocampal; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Polyamines; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine

Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Attention; Basal Nucleus of Meynert; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Indans; Male; Photic Stimulation; Piperazines; Piperidines; Pyridines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amides; Animals; Biphenyl Compounds; Cells, Cultured; Corpus Striatum; Dioxoles; Disease Models, Animal; Excitatory Amino Acid Agonists; GAP-43 Protein; Hippocampus; Humans; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Substantia Nigra

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminopyridines; Anesthetics, Local; Animals; Antipsychotic Agents; Benzopyrans; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Immunohistochemistry; In Situ Hybridization; Indoles; Indophenol; Male; Mice; Mice, Inbred C57BL; Microdialysis; Piperidines; Prazosin; Prefrontal Cortex; Quinoxalines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Thiazoles; Time Factors

Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Benzoxazines; Calcium; Calcium Channel Blockers; Cerebellum; Chelating Agents; Colforsin; Cyclopropanes; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Piperidines; Presynaptic Terminals; Pyrazoles; Rats; Rats, Wistar; Receptors, AMPA; Ryanodine; Synapses; Triazines; Triazoles

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Neural Inhibition; Neuromuscular Depolarizing Agents; Neurons; Nicotine; Organothiophosphorus Compounds; Patch-Clamp Techniques; Piperidines; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Nigra

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Central Nervous System Depressants; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Membrane Potentials; Mice; N-Methylaspartate; Neocortex; Patch-Clamp Techniques; Phenols; Piperidines; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Antagonists; Electric Stimulation; In Vitro Techniques; Male; Piperidines; Posterior Horn Cells; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzothiadiazines; Cell Separation; Cells, Cultured; Cerebellum; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; Lactic Acid; Mice; Nootropic Agents; Piperidines; Receptors, AMPA

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Indans; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Neuroprotective Agents; Nootropic Agents; Piperidines; Rats; Rats, Wistar; Receptors, Glutamate

Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction

Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebellum; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Morpholines; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Pyrazoles; Quinoxalines; Receptors, AMPA

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Dopamine; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Agonists; In Vitro Techniques; Indoles; Ion Channel Gating; Membrane Potentials; Mice; Motor Neurons; Patch-Clamp Techniques; Piperidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Spinal Cord

Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzoxazines; Biophysics; CA1 Region, Hippocampal; Caffeine; Calcium Channel Blockers; Dronabinol; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Piperidines; Presynaptic Terminals; Propanolamines; Pyrazoles; Quinoxalines; Receptor, Adenosine A1; Receptor, Cannabinoid, CB1; Xanthines

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Catalepsy; Drug Synergism; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Membrane Potentials; Olanzapine; Oxadiazoles; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Synaptic Transmission; Tetrahydronaphthalenes

Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Arachidonic Acids; Benzoxazines; Chick Embryo; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Agonists; Female; gamma-Aminobutyric Acid; Heterocyclic Compounds, 1-Ring; Homeostasis; Male; Morpholines; Motor Neurons; Naphthalenes; Nerve Net; Neuronal Plasticity; Patch-Clamp Techniques; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Signal Transduction; Spinal Cord; Synaptic Potentials; Urea

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Dietary Supplements; Dioxoles; Fatigue; Glutathione Peroxidase; Glycogen; Lactic Acid; Liver; Male; Mice; Mice, Inbred Strains; Muscle, Skeletal; Physical Endurance; Piperidines; Receptors, AMPA; Superoxide Dismutase; Swimming

Topics: Aggression; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Depression; Food Preferences; Glutamate Decarboxylase; Hypothalamus; Injections, Intraperitoneal; Male; Mice; Microinjections; Motor Activity; Neurons; Ondansetron; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Serotonin, 5-HT3; Social Isolation

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclin-Dependent Kinase 5; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; Neurons; Phosphopyruvate Hydratase; Piperidines; Pyridazines; Sensory Deprivation; Visual Cortex; Visual Pathways