alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with n-methylaspartate in 1049 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (2.86) | 18.7374 |
| 1990's | 525 (50.05) | 18.2507 |
| 2000's | 328 (31.27) | 29.6817 |
| 2010's | 137 (13.06) | 24.3611 |
| 2020's | 29 (2.76) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Brehm, L; Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Bräuner-Osborne, H; Conti, P; De Amici, M; De Micheli, C; De Sarro, G; Madsen, U; Rizzo, M; Stensbøl, TB; Toma, L | 1 |
| Boschi, D; Clausen, RP; Farnsworth, JC; Hansen, KB; Jensen, AA; Kastrup, JS; Lolli, ML; Møllerud, S; Nielsen, B; Passoni, A; Pickering, DS; Sainas, S; Temperini, P; Yi, F | 1 |
| Araldi, GL; Kozikowski, AP; Pshenichkin, S; Steensma, D; Surina, E; Tückmantel, W; Wang, S; Wroblewski, JT | 1 |
| Amir, A; Contreras-Sanz, A; Foti, A; Fruttero, R; Gasco, A; Giordano, C; Hansen, KB; Johansen, TN; Lolli, ML; Nielsen, B; Pickering, DS; Rolando, B | 1 |
| Greene, RW; McCarley, RW; Stevens, DR | 1 |
| Cerne, R; Randic, M | 1 |
| Hong, JS; McMillian, M; Pennypacker, KR | 1 |
| Bloms, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Beninger, RJ; Boegman, RJ; Cockhill, J; Jhamandas, K | 1 |
| Hansen, JJ; Krogsgaard-Larsen, P; Miledi, R; Nielsen, B; Schousboe, A; Wahl, P | 1 |
| Carlà, V; Moroni, F | 1 |
| Fedorov, NB; Reymann, KG; Screbitsky, VG | 1 |
| Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
| Maruyama, M; Nakazawa, M; Takeda, K | 1 |
| Haley, JE; Kitto, KF; Wilcox, GL | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Garrone, B; Pittaluga, A; Raiteri, M | 1 |
| Bobichon, C; Cordi, A; Curutchet, P; de Carvalho, LP; Guet, T; Lambolez, B; Lepagnol, JM; Moreau, C; Randle, JC | 1 |
| Andersen, CF; Frandsen, A; Schousboe, A | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Fain, GL; Yazejian, B | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Donevan, SD; Jones, SM; Rogawski, MA | 1 |
| Martin, D; McNamara, JO; Nadler, JV | 1 |
| Gordon, FJ; Pawloski-Dahm, C | 1 |
| Kawai, N; Nakajima, T; Robinson, HP; Shimazaki, K; Takenawa, T | 1 |
| Balázs, R; Hack, N; Kumar, KN; Michaelis, E; Resink, A; Van der Valk, JB | 1 |
| Lodge, D; Millar, JD; Pralong, E | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 1 |
| Crawley, JN; Finiels-Marlier, F; Leppin, C; Montpied, P; Paul, SM | 1 |
| Dildy-Mayfield, JE; Harris, RA | 1 |
| Greenberger, V; Segal, M | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Chiamulera, C; Costa, S; Reggiani, A; Valerio, E | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Parks, TN; Zhou, N | 1 |
| Bleakman, D; Chard, PS; Glaum, SR; Miller, RJ; Rusin, KI | 1 |
| Randic, M; Rusin, KI; Ryu, PD | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Kelso, SR; Leonard, JP; Nelson, TE | 1 |
| Arvin, B; Lekieffre, D; Meldrum, B; Moncada, C | 1 |
| Lodge, D; Zeman, S | 1 |
| Oostveen, JA; Pregenzer, JF; Williams, LR | 1 |
| McDonald, JW; Schoepp, DD | 1 |
| Davies, JA; Dickie, BG; Lewis, MJ | 1 |
| Bonhaus, DW; McNamara, JO | 1 |
| Budai, D; Larson, AA; Wilcox, GL | 2 |
| Baganoff, MP; Davies, MS; Grishin, EV; Lanthorn, TH; Volkova, TM; Watson, GB; Wiegand, RC | 1 |
| Courtney, MJ; Nicholls, DG | 1 |
| Barnard, EA; Bond, A; Henley, JM | 1 |
| Albensi, BC; Artman, LD; Jackson, H; Jasys, VJ; Mueller, AL; Nemeth, EF; Parks, TN; Saccomano, NA; Volkmann, RA | 1 |
| Jones, MG; Lodge, D; Palmer, AJ | 1 |
| Supko, DE; Uretsky, NJ; Wallace, LJ | 1 |
| Dure, LS; Penney, JB; Young, AB | 1 |
| Cotman, CW; Koh, JY; Lin, A; Palmer, E | 1 |
| Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Blazynski, C; Linn, DM; Massey, SC; Redburn, DA | 1 |
| Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Shreve, PE; Uretsky, NJ | 4 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Cull-Candy, SG; Farrant, M | 1 |
| Eaton, SA; Roberts, WA; Salt, TE | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Garthwaite, J; Southam, E | 1 |
| Christenson, J; Grillner, S | 1 |
| Cai, NS; Erdö, SL; Kiss, B | 1 |
| Cull-Candy, SG; Traynelis, SF | 1 |
| Hećimović, H; Randić, M; Ryu, PD | 1 |
| Mayer, ML | 1 |
| Legendre, P; Westbrook, GL | 1 |
| Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N | 1 |
| Aniksztejn, L; Ben-Ari, Y; Bregestovski, P | 1 |
| Uretsky, NJ; Wallace, LJ | 1 |
| Jones, MG; Lodge, D | 1 |
| Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C | 1 |
| Arnold, MB; Elzey, T; Leander, JD; Lodge, D; Ornstein, PL; Paschal, JW; Schoepp, DD | 1 |
| Leander, JD; Ornstein, PL; Salhoff, CR; Schoepp, DD | 1 |
| Aniksztejn, L; Ben-Ari, Y | 1 |
| Larson, J; Lynch, G | 1 |
| Brehm, L; Jørgensen, FS; Krogsgaard-Larsen, P; Madsen, U; Schaumburg, K | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Butterworth, RF; Cotman, CW; Giguere, JF; Peterson, C | 1 |
| Baimbridge, KG; Choi, DW; Koh, J; Weiss, JH | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Meldrum, BS; Smith, SE | 1 |
| Boos, R; Müller, F; Wässle, H | 1 |
| Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J; Shand, A | 1 |
| Thomson, AM | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Bian, XP; Martin, D; Morrisett, RA; Swartzwelder, HS; Wilson, WA | 1 |
| Ehrlich, D; Morgan, IG; Tung, NN | 1 |
| Anis, NA; Jones, MG; Lodge, D | 1 |
| Birch, PJ; Hayes, AG; Rogers, H | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Choi, DW; Hartley, DM; Koh, J; Weiss, JH | 1 |
| Johnson, BG; McQuaid, LA; Schoepp, DD; Smith, EC | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Ross, SM; Roy, DN; Spencer, PS | 1 |
| Cotman, CW; Monaghan, DT; Palmer, E | 2 |
| Girdlestone, D; Thomson, AM; West, DC | 1 |
| O'Dell, TJ | 1 |
| Westerberg, E; Wieloch, TW | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Beart, PM; Cincotta, M; Summers, RJ | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Gordon, FJ; Leone, C | 1 |
| Cotman, CW; Monaghan, DT; Yao, D | 1 |
| Cotman, CW; Ganong, AH | 1 |
| Cotman, CW; Monaghan, DT; Westerberg, E; Wieloch, T | 1 |
| Choi, DW; Koh, J; Peters, S | 1 |
| Morgan, IG | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Benavides, J; Carter, C; Fage, D; Scatton, B | 1 |
| Fischbach, GD; Thio, LL; Trussell, LO; Zorumski, CF | 2 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| López-Colomé, AM; Roberts, PJ; Somohano, F | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 1 |
| Foster, AC; Gill, R; Woodruff, GN | 1 |
| Massey, SC; Miller, RF | 1 |
| Eng, P; Hösli, E; Hösli, L; Lehmann, R | 1 |
| Baker, RC; Winter, CR | 1 |
| Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S | 1 |
| Barbeito, L; Estevez, AG; Stutzmann, JM | 1 |
| Botscheller, ML; DeKosky, ST; Marion, DW; Palmer, AM; Styren, SD; Swedlow, PE | 1 |
| Aronica, E; Balázs, R; Casabona, G; Condorelli, DF; Corsaro, M; Dell'Albani, P; Genazzani, AA; Nicoletti, F | 1 |
| Barnes, KA; Buchan, AM; Huang, ZG; Lesiuk, H; Li, H; Smith, KE; Xue, D | 1 |
| Lerma, J; Mellström, B; Naranjo, JR; Paternain, AV | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 2 |
| MacDermott, AB; Reichling, DB | 1 |
| Siesjö, B | 1 |
| Connor, JA; Linden, DJ; Smeyne, M | 1 |
| Fedorov, NB; Reymann, KG | 1 |
| Hole, K; Lund, A; Mjellem, N | 1 |
| Bisaga, A; Danysz, W; Jankowska, E; Kostowski, W; Krzascik, P; Palejko, W | 1 |
| Fedele, E; Raiteri, M; Versace, P | 1 |
| Miller, RF; Thoreson, WB | 1 |
| Cheng, B; Christakos, S; Mattson, MP | 1 |
| Jahr, CE; Tong, G | 1 |
| Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL | 2 |
| Boxer, PA; Robichaud, LJ | 1 |
| Glowinski, J; Prémont, J; Stella, N; Tencé, M | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Lees, GJ; Leong, W | 1 |
| Barnes, K; Buchan, AM; Huang, ZG; Lesiuk, HJ; Smith, KE; Xue, D | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Donias, HW; Ha, LH; Spears, LC; Stanley, BG; Willett, VL | 1 |
| Klitgaard, H; Laudrup, P | 2 |
| Balasubramaniam, R; Collingridge, GL; Harvey, J | 1 |
| Block, F | 1 |
| Johnston, MV; Supko, DE | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R; Tribillac, F | 1 |
| Chiodo, LA; Freeman, AS; Zhang, J | 1 |
| Gyevai, A; Mike, A; Osipenko, O; Vizi, ES | 1 |
| Schwarcz, R; Shepard, PD; Wu, HQ | 1 |
| Boel, E; Suzdak, PD; Thomsen, C | 1 |
| Burnett, JP; Desai, MA; Schoepp, DD | 1 |
| Luscombe, GP; Mason, R; Scott, G | 1 |
| Advokat, C; Bertman, L; Prejean, J | 1 |
| Argiolas, A; Melis, MR; Stancampiano, R | 1 |
| Engel, JA; Johannessen, K; Svensson, L; Zhang, J | 1 |
| Hamada, T; Shibata, S; Watanabe, A; Watanabe, S | 1 |
| Herrera, AJ; Osborne, NN | 1 |
| Massieu, L; Tapia, R | 1 |
| Chizh, BA; Cumberbatch, MJ; Headley, PM | 3 |
| Azuma, Y; Han, D; Ogita, K; Sakamoto, T; Yoneda, Y | 1 |
| Amico, C; Condorelli, DF; Dell'Albani, P; Giuffrida-Stella, AM; Kaczmarek, L; Lukasiuk, K | 1 |
| Hamada, T; Ono, M; Shibata, S; Watanabe, A; Watanabe, S | 1 |
| de Vente, J; Garthwaite, J; Gittins, SR; Morris, R; Southam, E | 1 |
| Wu, C | 1 |
| Endo, H; Ichimura, M; Mori, S; Okamoto, M | 1 |
| Adler-Graschinsky, E; Butta, NV; Lorenzo, PS | 1 |
| Bruno, VM; Choi, DW; Dugan, LL; Giffard, RG; Goldberg, MP | 1 |
| Lancaster, J; Neale, JH; Sweetnam, PM; Valivullah, HM | 1 |
| Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Gruner, R; Parsons, CG; Rozental, J | 1 |
| Binns, KE; Do, KQ; Salt, TE | 1 |
| Choi, DW; Weiss, JH; Yin, HZ | 1 |
| Björkman, R; Hallman, KM; Hedner, J; Hedner, T; Henning, M | 2 |
| Advokat, C; Ghorpade, A; Wolf, E | 1 |
| Lücke, T; Neugebauer, V; Schaible, HG | 1 |
| Artaud, F; Chéramy, A; Desban, M; Galli, T; Glowinski, J; Godeheu, G; Torrens, Y | 1 |
| Hori, Y; Kanda, K | 2 |
| Gebhart, GF; Meller, ST | 1 |
| Dekermendjian, K; Frandsen, A; Nielsen, M; Schousboe, A; Witt, MR | 1 |
| Abe, I; Fujishima, M; Tsuchihashi, T | 1 |
| Madamba, SG; Nie, Z; Siggins, GR | 1 |
| Albert, A; Bonhomme, V; Collette, J; Hans, P; Moonen, G | 1 |
| Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E | 1 |
| Kasparov, S; Pawelzik, H; Zieglgänsberger, W | 1 |
| García, Y; Ibarra, C; Jaffé, EH | 1 |
| Collins, DR; Davies, SN | 2 |
| Luo, D; Vincent, SR | 1 |
| Büsselberg, D; Haas, H; Platt, B | 1 |
| French, ED; Wang, T | 3 |
| Oja, SS; Saransaari, P | 4 |
| Obrenovitch, TP; Urenjak, J; Zilkha, E | 1 |
| Anderson, LA; Kelland, MD; Soltis, RP; Walters, JR | 1 |
| Ossowska, K | 2 |
| Carvalho, AP; Carvalho, CM; Duarte, CB; Ferreira, IL; Santos, PF | 1 |
| Cumberbatch, MJ; Headley, PM; Herrero, JF | 1 |
| Chen, JC; Chesler, M; Gottfried, JA; Smith, SE | 1 |
| Devillers, JP; Simonnet, G | 1 |
| Araki, N; Fukuuchi, Y; Komatsumoto, S; Ohta, K; Shibata, M; Shimazu, K | 1 |
| Dickie, BG; Greenfield, SA; Jones, SA; Klegeris, A | 1 |
| Beal, MF; Cipolloni, PB; Ferrante, RJ; Henshaw, DR; Jenkins, BG; Kowall, NW; Rosen, BR; Schulz, JB; Siwek, D | 1 |
| Greenamyre, JT; Greene, JG | 1 |
| Bloms-Funke, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Domenici, MR; Longo, R; Sagratella, S; Scotti de Carolis, A | 1 |
| Köhling, R; Lücke, A; Moskopp, D; Speckmann, EJ; Straub, H; Wassmann, H | 1 |
| Rothwell, NJ; Strijbos, PJ | 1 |
| Dowling, JE; Grant, GB | 1 |
| Hatt, H; Jensen, P; Lowe, D; Smith, DO; Temkin, R | 1 |
| Bahr, BA; Lynch, G; Park, GY; Tiriveedhi, S | 1 |
| Kawai, N; Masuzawa, T; Oguro, K; Robinson, HP; Tsubokawa, H | 1 |
| Acciarri, N; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Ferraro, L; Morari, M; Piazza, G | 1 |
| Gustafsson, B; Karpefors, M; Wigström, H; Xiao, MY | 1 |
| Amagasu, SM; Bruno, VM; Dugan, LL; Giffard, RG | 1 |
| Park, J; Tasker, RC; Vornov, JJ | 1 |
| Hu, B; Nissen, R; Renaud, LP | 1 |
| Carvalho, AP; Carvalho, CM; Duarte, CB; Malva, JO | 1 |
| Bettler, B; Mulle, C | 1 |
| Desai, MA; Monn, JA; Schoepp, DD; Valli, MJ | 1 |
| Horimoto, N; Kawamoto, I; Nabekura, J; Ogawa, T | 1 |
| Inoue, H; Koizumi, S; Ochi, M; Shibata, S; Watanabe, S | 1 |
| Balázs, R; Hack, N | 1 |
| Herron, C; Hjelmstad, GO; Malenka, RC; Nicoll, RA; Selig, DK | 1 |
| Bischoff, F; Ebert, B; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Mobley, SL; Rance, NE; Wenk, GL | 1 |
| McCarthy, KD; Porter, JT | 1 |
| Boulton, CL; Garthwaite, J; Mayer, B; Nielsen, EB; Schmidt, K; Southam, E | 1 |
| Pinsky, PF; Rinzel, J | 1 |
| Lu, YM; Weiss, JH; Yin, HZ | 1 |
| Christoffersen, CL; Meltzer, LT | 1 |
| Hill, JM; Kaufman, MP; Wong, MK | 1 |
| Durkin, JP; Wang, Y | 1 |
| Benvenga, MJ; Leander, JD; Ornstein, PL | 1 |
| LeDoux, JE; Li, XF; Phillips, R | 1 |
| Gorman, AM; Grieve, A; Griffiths, R | 1 |
| Cheng, B; Fabian, T; Furukawa, K; Goodman, Y; Kihiko, M; Mattson, MP; O'Keefe, JA | 1 |
| Catania, MV; Hollingsworth, Z; Penney, JB; Young, AB | 2 |
| Lodge, D; Palmer, AJ | 1 |
| Craig, CG; White, TD | 1 |
| Baron, SP; Woods, JH | 1 |
| Andou, Y; Enomoto, R; Kataoka, K; Mitani, A; Ogita, K; Yoneda, Y | 1 |
| Birse, EF; Eaton, SA; Jane, DE; Jones, PL; Pook, PC; Porter, RH; Roberts, PJ; Sunter, DC; Udvarhelyi, PM; Wharton, B | 1 |
| Herrling, PL; Meier, CL | 1 |
| Lemaire, S; Shukla, VK | 1 |
| Chen, LL; Harris, RA; Lin, LH | 1 |
| Alagarsamy, S; Johnson, KM; Lonart, G | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Block, F; Schwarz, M; Sontag, KH | 1 |
| Brackley, PT; Usherwood, PN | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Bowlby, MR | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Cai, N; Erdö, SL; Lakics, V | 1 |
| Bockaert, J; Cragoe, EJ; Dumuis, A; Fagni, L; Manzoni, O; Prézeau, L; Sebben, M | 1 |
| Bridges, RJ; Miller, S; Nunn, PB | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Abutidze, K; Barnard, EA; Kerry, CJ; Mellor, IR; Sudan, HL; Usherwood, PN | 1 |
| Schultz, K; Weiler, R | 1 |
| Fukuda, H; Hicks, TP; Kobayashi, T; Nagao, T; Oka, JI | 1 |
| Dee, MG; Ha, LH; Spears, LC; Stanley, BG | 1 |
| Rigor, BM; Schurr, A | 1 |
| Albin, RL; Kremer, B; Tallaksen-Greene, SJ | 1 |
| Durand, J; Engberg, I; Ouardouz, M; Tarnawa, I | 1 |
| Angelides, KJ; Benke, TA; Collingridge, GL; Jones, OT | 1 |
| Jane, DE; Jones, PL; Pook, PC; Salt, TE; Sunter, DC; Watkins, JC | 1 |
| Naarala, J; Nykvist, P; Savolainen, K; Tuomala, M | 1 |
| Barrionuevo, G; Fleck, MW; Henze, DA; Palmer, AM | 1 |
| Yoneda, Y | 1 |
| Dykstra, CL; Gebhart, GF; Meller, ST | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Block, F; Schmitt, T; Schwarz, M | 1 |
| Lehmann, JC; Procureur, D; Wood, PL | 1 |
| Netzer, R; Pflimlin, P; Trube, G | 1 |
| Constantine-Paton, M; Hickmott, PW | 1 |
| Buchwald, NA; Cepeda, C; Levine, MS | 1 |
| Cerne, R; Jiang, MC; Kolaj, M; Randic, M; Rusin, KI | 1 |
| Klockgether, T; Turski, L | 1 |
| Clements, JD; Oleskevich, S; Williams, JT | 1 |
| De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Maura, G; Raiteri, M | 1 |
| Battaglia, G; Bruno, V; Copani, A; Giffard, RG; Nicoletti, F; Raciti, G; Raffaele, R; Shinozaki, H | 1 |
| Böing, C; Fink, K; Göthert, M; Schmitz, V | 1 |
| Bond, A; Lodge, D | 1 |
| Bleakman, D; Leander, JD; Lodge, D; Ornstein, PL; Palmer, AJ; Salhoff, CR; Schoepp, DD; Tizzano, JP; Wright, RA | 1 |
| Kumamoto, E; Murata, Y | 1 |
| Gean, PW; Hsu, KS; Huang, CC | 1 |
| Crowley, WR; Parker, SL | 1 |
| Cordi, AA; Desos, P; Lepagnol, JM; Lestage, P; Morain, P | 1 |
| Arnt, J; Krogsgaard-Larsen, P; Lenz, SM; Madsen, U; Sánchez, C | 1 |
| Karpefors, M; Niu, YP; Wigström, H; Xiao, MY | 2 |
| Altemus, KL; Cepeda, C; Colwell, CS; Levine, MS | 1 |
| Church, J; McLarnon, JG; Sawyer, DC | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Ben-Ari, Y; Congar, P; Khazipov, R | 1 |
| Friedemann, MN; Gerhardt, GA | 1 |
| Cebers, G; Kalda, A; Liljequist, S | 1 |
| Jedema, HP; Moghddam, B | 1 |
| Alberi, S; de Bilbao, F; Dubois-Dauphin, M; Raggenbass, M | 1 |
| Brann, DW; Mahesh, VB; Zamorano, PL; Zuo, Z | 1 |
| Bristow, DR; Platt, KP | 1 |
| Auth, F; DeBoer, P; Moor, E; Westerink, BH | 1 |
| Allen, NK; Arnold, MB; Bleisch, T; Borromeo, PS; Leander, JD; Lodge, D; Lugar, CW; Ornstein, PL; Schoepp, DD | 1 |
| Ebling, FJ; Hastings, MH; Hui, Y; Maywood, ES; Mirakhur, A | 1 |
| Kumar, V; Lincoln, GA; Tortonese, DJ | 1 |
| Chiba, C; Saito, T | 2 |
| Buisson, A; Choi, DW; Yu, SP | 1 |
| Bonasera, L; Carlton, SM; Zhou, S | 1 |
| Kaneko, A; Sasaki, T | 1 |
| Carvalho, AP; Duarte, CB; Sánchez-Prieto, J; Santos, PF | 1 |
| Chizh, BA; Headley, PM | 1 |
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| Jadi, M; Mel, BW; Polsky, A; Schiller, J | 1 |
| Gulich, K; Hayess, K; Luch, A; Oelgeschläger, M; Pohl, EE; Riebeling, C; Seiler, AE; Sittner, D; Slawik, B; Visan, A | 1 |
| Bizot, JC; Boulouard, M; Burgo, A; Contremoulins, V; Danglot, L; Dauphin, F; Freret, T; Galli, T; Gaspar, P; Hyenne, V; Le Roux, N; Narboux Nême, N; Poncer, JC; Roumier, A; Simmler, MC; Vodjdani, G | 1 |
| Gocel, J; Larson, J | 1 |
| Barson, JR; Chen, A; Chen, YW; Hoebel, BG; Leibowitz, SF | 1 |
| Behabadi, BF; Jadi, M; Mel, BW; Polsky, A; Schiller, J | 1 |
| Herbison, AE; Lee, K; Liu, X | 1 |
| Kalinina, NI; Kurchavyĭ, GG; Veselkin, NP | 1 |
| Mejia-Gervacio, S | 1 |
| Nicoll, RA; Shipman, SL | 1 |
| Ben Hamida, S; Carnicella, S; Darcq, E; Gibb, SL; Lanfranco, MF; Ron, D; Wang, J; Zhu, W | 1 |
| de Wit, J; DeNardo, LA; Ghosh, A; Otto-Hitt, S | 1 |
| Blanchet, C; Labrousse, VF; Lanore, F; Mulle, C; Normand, E; Szabo, Z | 1 |
| Funahashi, R; Komatsu, Y; Maruyama, T; Yoshimura, Y | 1 |
| Bernardi, G; Berretta, N; Centonze, D; Feligioni, M; Gentile, A; Mandolesi, G; Mango, D; Mercuri, NB; Mori, F; Musella, A; Nicoletti, F; Nisticò, R; Piccinin, S; Pignatelli, M | 1 |
| Cho, S; Hahn, SJ; Hong, YJ; Lee, J; Yang, JS; Yoon, SH | 1 |
| Kato, F; Nagase, M; Ochiai, T; Sato, M; Takahashi, Y; Watabe, AM | 1 |
| Siekmeier, PJ; vanMaanen, DP | 1 |
| Amini, M; Baudry, M; Beique, JC; Bergeron, R; Farazifard, R; Greer, PA; Hage, F; Lagace, DC; Ma, CL; Park, DS; Savitt, JM; Slack, RS; Vanderluit, J; Zhang, Y; Zhu, G; Zoltewicz, JS | 1 |
| Fujita, T; Jiang, CY; Kumamoto, E; Liu, T; Luo, SW | 1 |
| Adrover, MF; Alvarez, VA; Bock, R; Christensen, CH; Dobi, A; Gremel, CM; Kaplan, AR; Kramer, PF; Markey, E; Shin, JH | 1 |
| Nikitin, VP; Solntseva, SV | 1 |
| Chagneau, C; Dallerac, G; Davis, S; Farley, S; Hanauer, A; Laroche, S; Morice, E; Pannetier, S; Poirier, R; Vaillend, C | 1 |
| Thanapitak, S; Toumazou, C | 1 |
| Liu, SC; Wang, Y | 1 |
| Chizhov, AV | 1 |
| Mattson, MP; Wang, Y | 1 |
| Mokrushin, AA; Pavlinova, LI | 1 |
| Counotte, DS; O'Donnell, P; Schiefer, C; Shaham, Y | 1 |
| Kessels, HW; Lohmann, C | 1 |
| Bayer, KU; Liu, QS; Liu, X; Liu, Y; Olsen, CM; Qi, J; Wilkinson, B; Zhong, P | 1 |
| Batista, Ede J; Brasil, A; Crespo-Lopez, ME; Herculano, AM; Lima, MG; Matos Oliveira, KR; Maximino, C; Picanço-Diniz, DL; Rocha, FA | 1 |
| Chen, D; Ding, L; Gao, R; Gao, XY; Kang, YM; Wang, JJ; Zhang, LL; Zhu, GQ | 1 |
| Carr, JA; Fu, Z; Go, A; Pamenter, ME; Powell, FL; Reid, SG | 1 |
| Alberch, J; Ceña, V; Collon, KW; Domercq, M; Fernández-Díez, B; Franco, R; Giralt, A; Giralt, E; Gottlieb, M; Lopez, I; Martínez-Pinilla, E; Matute, C; Moreno, B; Parent, JM; Posadas, I; Sánchez-Gómez, MV; Teixido, M; Villoslada, P; Zhang, H | 1 |
| Bayer, KU; Han, VZ; Turecek, J; Welsh, JP; Yuen, GS; Zeng, XH | 1 |
| Itohara, S; Iwasato, T; Luo, W; Mizuno, H; Saito, YM; Sato, T; Tarusawa, E; Yoshimura, Y | 1 |
| Chen, G; Dohi, S; Iida, H; Kawasaki, Y; Tanabe, K; Yanagidate, F; Zhang, L | 1 |
| Hayden, MR; Kolodziejczyk, K; Parsons, MP; Raymond, LA; Southwell, AL | 1 |
| Espallergues, J; Lüscher, C; O'Connor, EC; Pascoli, V; Terrier, J; Valjent, E | 1 |
| Ammassari-Teule, M; Bagetta, V; Calabresi, P; Costa, C; Fejtova, A; Ghiglieri, V; Gundelfinger, ED; Morelli, E; Pendolino, V; Picconi, B; Pignataro, A | 1 |
| Fukushima, K; Imaizumi, Y; Ito, M; Kohmura, N; Sawada, K; Sugawara, M; Tabata, Y; Yamazaki, K | 1 |
| Borsello, T; Calabresi, P; Costa, C; de Iure, A; Di Filippo, M; Ghiglieri, V; Sclip, A; Tantucci, M; Tozzi, A | 1 |
| Asensio, CS; Edwards, RH; Incontro, S; Nicoll, RA | 1 |
| Blackshaw, S; Fu, C; Hu, S; Ma, TM; Paul, BD; Snyder, SH; Wolosker, H; Zhu, H | 1 |
| Akbarali, HI; Bowers, MS; Fitting, S; Hauser, KF; Knapp, PE; Marks, WD; Zou, S | 1 |
| Kohlmeier, KA; McNair, LF | 1 |
| Rodríguez-Manzo, G | 1 |
| Beckley, JT; Hughes, BA; Kalivas, PW; Randall, PK; Smith, RJ; Woodward, JJ | 1 |
| Fu, T; Guo, L; Huang, P; Li, C; Lu, Q; Xu, X | 1 |
| Endo, S; Kazama, T; Kobayashi, Y; Ohta, H; Pagès, G; Pouysségur, J; Satoh, Y; Takaenoki, Y; Takamatsu, I; Yufune, S | 1 |
| Akaike, N; Kotani, N; Wakita, M; Yamaga, T | 1 |
| Bonsi, P; Mandolesi, G; Pisani, A; Ponterio, G; Sciamanna, G | 1 |
| Briggs, SB; Keralapurath, MM; Wagner, JJ | 1 |
| Kreitzer, AC; Lalive, AL; Parker, PR | 1 |
| Jia, Y; Parker, D | 1 |
| Bermúdez-Rattoni, F; Guzmán-Ramos, K; Osorio-Gómez, D | 1 |
| Nakatsuka, T; Nishio, N; Sonekatsu, M; Taniguchi, W; Tsutsui, S; Yamada, H; Yamanaka, M; Yoshida, M | 1 |
| Aimone, JB; Dieni, CV; Kuo, CT; Overstreet-Wadiche, L; Panichi, R; Wadiche, JI | 1 |
| Adam, I; Kobalz, U; Mendoza, E; Scharff, C; Wohlgemuth, S | 1 |
| Chianca, DA; de Menezes, RC; Machado, NL; Silva, FC | 1 |
| Hennig, MH; Lansner, A; Lindén, H; Tully, PJ | 1 |
| Di Maio, V; Santillo, S; Ventriglia, F | 1 |
| Baldridge, WH; Blandford, SN | 1 |
| Ma, LQ; Peng, YZ; Shen, FY; Wang, B; Wang, ZR; Wen, W; Zhang, TT; Zhao, X | 1 |
| Amédée, T; Borralleras, C; Campuzano, V; Mato, S; Matute, C; Mulle, C; Pérez-Jurado, LA | 1 |
| Chen, XJ; Li, CY; Ye, HB; Zhang, WT; Zhou, HQ | 1 |
| Dharkar, P; Han, TH; Lee, CH; Li, Y; Mayer, ML; Serpe, M | 1 |
| Machado-Vieira, R; Zarate, CA | 1 |
| Heimel, JA; Kamphuis, W; Levelt, CN; Min, R; Saiepour, MH | 1 |
| Dragon, DN; Lin, LH; Talman, WT | 1 |
| Ben-Eliyahu, S; Benbenishty, A; Frere, S; Goshen, I; Lahav, C; Milshtein-Parush, H; Regev, L; Slutsky, I | 1 |
| Elefant, F; Gao, WJ; Gulchina, Y; Snyder, MA; Xu, SJ | 1 |
| Corsini, S; Ghezzi, F; Monni, L; Nistri, A | 1 |
| Cui, J; Ng, LJ; Volman, V | 1 |
| Chen, L; Huang, M; Jiang, B; Li, S; Li, Y; Wang, L; Wang, X; Yang, Y; Zhang, X | 1 |
| Blier, P; Ebrahimzadeh, M; El Mansari, M | 1 |
| Carter, AG; McGarry, LM | 1 |
| Avendaño, C; Fernández-Montoya, J; Negredo, P | 1 |
| Berke, JD; Kreitzer, AC; Owen, SF | 1 |
| Gilbert, JR; Nugent, AC; Wills, KE; Yarrington, JS; Zarate, CA | 1 |
| Franke, H; Illes, P; Khan, MT; Liu, J; Nerlich, J; Tang, Y | 1 |
| Brooks, G; Hasekiu, E; Ingle Gonzalez, JE; Kusi, M; Noakes, J | 1 |
| Bellone, C; Bimpisidis, Z; Creed, M; Dorst, MC; Dumas, S; Lüscher, C; Papathanou, M; Pettersson, H; Silberberg, G; Wallén-Mackenzie, Å | 1 |
| Chen, Q; Deng, W; Hu, X; Li, K; Li, L; Li, T; Lu, T; Lv, L; Ma, X; Man Wu, H; Ren, H; Sham, P; Tan, L; Tan, Q; Wang, C; Wang, L; Wang, Q; Wang, Y; Yan, H; Yang, F; Yang, G; Yang, J; Yu, H; Yue, W; Zhang, D; Zhang, F; Zhang, H; Zhang, Y; Zhao, L | 1 |
| Harris, DA; Le, NTT; Wu, B | 1 |
| Bobadilla, AC; Gipson, CD; Heinsbroek, JA; Kalivas, PW; Roberts-Wolfe, DJ; Smith, ACW; Spencer, SM | 1 |
| Ben-Shalom, R; Bender, KJ; Burke, KJ; Clarkson, RL; Keeshen, CM; Sanders, SJ; Spratt, PWE | 1 |
| Eyigor, O; Gok-Yurtseven, D; Kafa, IM; Minbay, Z | 1 |
| Amsalem, O; Eyal, G; Gevaert, M; Kumbhar, P; Rogozinski, N; Schürmann, F; Segev, I | 1 |
| Babaev, AA; Epifanova, EA; Tarabykin, VS; Turovskaya, MV; Turovsky, EA | 1 |
| Ábrahám, IM; Cho, DH; Han, SK; Jang, SH; Park, SA; Rijal, S | 1 |
| Croizier, S; Gervais, M; Labouèbe, G; Picard, A; Thorens, B | 1 |
| Esmaili-Shahzade-Ali-Akbari, P; Hosseinzadeh, H; Mehri, S | 1 |
| Alwin Gieselmann, M; Brandt, C; Dasilva, M; Distler, C; Thiele, A | 1 |
| Brüll, M; Falt, T; Karreman, C; Klima, S; Leist, M; Schwamborn, JC; Spreng, AS; Suciu, I; Waldmann, T | 1 |
| Kamanaka, G; Kanemaru, M; Oka, JI; Sanai, E; Sasaki-Hamada, S | 1 |
| Giesen, J; Koesling, D; Mergia, E; Russwurm, M | 1 |
| Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P | 1 |
| Mantilla, CB; Rana, S; Sieck, GC; Zhan, WZ | 1 |
| Collingridge, GL; Monaghan, DT | 1 |
| Cheng, F; Dai, N; Du, L; He, H; Kim, JJ; Zhu, F | 1 |
| Cabrera-Pastor, A; Felipo, V; Sancho-Alonso, M; Taoro-Gonzalez, L; Teruel-Martí, V | 1 |
| Anstötz, M; Ferraguti, F; Kasugai, Y; Lübke, JHR; Molnar, E; Rollenhagen, A; Sätzler, K; Zimmermann, K | 1 |
| Cha, S; Guo, G; Li, J; Meng, L; Wu, F; Zhang, H; Zhang, J; Zhang, W; Zhu, W | 1 |
| Chen, SR; Pan, HL; Shao, JY; Zhou, JJ | 1 |
| Mielke, JG; Thacker, JS | 1 |
| Chang, A; Chang, Y; Wang, SJ | 1 |
| Bhatia, A; Joshi, R; Kaur, G; Kumar, R; Medhi, B; Mishra, A; Prajapat, M; Sarma, P; Sharma, A; Singla, R | 1 |
| Dai, J; Golf, SR; Liakath-Ali, K; Südhof, TC | 1 |
| Dash, SS; Kandy, SK; Markandeya, YS; Mehta, B; Nimonkar, MM | 1 |
| Bittner, D; Düzel, E; Goihl, A; Korte, M; Körtvélyessy, P; Leypoldt, F; Ludewig, S; Reinhold, D; Rohne, J; Salzburger, L; Schraven, B | 1 |
| Südhof, TC | 1 |
| Bigagli, E; Caffino, L; Castillo Díaz, F; Curti, L; Dani, C; Fumagalli, F; Gerace, E; Ilari, A; Luceri, C; Mannaioni, G; Masi, A; Mottarlini, F | 1 |
| Bebko, K; Gabryś, H; Krzeszowiec, W; Lewandowska, A; Lyczakowski, JJ; Scholz, SS | 1 |
| Li, CH; Liu, YZ | 1 |
| Gipson, CD; Hong, M; Khatri, SN; Maher, EE; Sadek, S; Stoops, WW; Ulangkaya, H; Woodcox, AM | 1 |
25 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and n-methylaspartate
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Effect of GABAergic and glutamatergic drugs injected into the ventral pallidum on locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Ibotenic Acid; Kainic Acid; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin | 1991 |
The role of excitatory amino acids in experimental models of Parkinson's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Catalepsy; Disease Models, Animal; Excitatory Amino Acids; Levodopa; N-Methylaspartate; Oxidopamine; Parkinson Disease; Rats | 1994 |
Review: neurotransmitter receptors. II. AMPA and kainate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cloning, Molecular; Ganglia, Spinal; Hippocampus; Humans; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Time Factors | 1995 |
[Receptive mechanisms of excitatory amino acid signals].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ischemia; Epilepsy; Ibotenic Acid; Kainic Acid; Ligands; N-Methylaspartate; Receptors, Amino Acid; Signal Transduction; Transcription Factors | 1993 |
Neurodegenerative disorders: clues from glutamate and energy metabolism.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Damage, Chronic; Brain Injuries; Brain Ischemia; Energy Metabolism; Excitatory Amino Acid Antagonists; Glutamates; Humans; N-Methylaspartate; Nerve Degeneration; Nervous System Diseases; Neurotoxins | 1996 |
Glutamatergic transmission in the nucleus tractus solitarii: from server to peripherals in the cardiovascular information superhighway.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Baroreflex; Cardiovascular Physiological Phenomena; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Solitary Nucleus | 1997 |
[Stimulating amino acids in epilepsy: possibilities of treatment].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anticonvulsants; Asparagine; Epilepsy; Female; Glutamine; Humans; Kainic Acid; Male; N-Methylaspartate; Synaptic Transmission | 2000 |
The role of amino acid neurotransmitters in the regulation of pituitary gonadotropin release in fish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Female; Fishes; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropins, Pituitary; Luteinizing Hormone; Male; Models, Biological; N-Methylaspartate; Neurotransmitter Agents; Phylogeny; Sex Factors | 2000 |
An overview of acute stroke therapy: past, present, and future.
Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy | 2000 |
Role of excitatory amino acids in developmental epilepsies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Epilepsy; Excitatory Amino Acids; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Synaptic Transmission | 2001 |
Glutamate antagonists limit tumor growth.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antineoplastic Agents; Cell Division; Cell Movement; Drug Synergism; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; N-Methylaspartate; Tumor Cells, Cultured | 2002 |
Excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acids; Glutamic Acid; Humans; N-Methylaspartate; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 2002 |
Structural plasticity and tianeptine: cellular and molecular targets.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents, Tricyclic; Apoptosis; Atrophy; Dentate Gyrus; Depressive Disorder, Major; Glutamic Acid; Hippocampus; Humans; N-Methylaspartate; Neuronal Plasticity; Neurons; Serotonin; Thiazepines | 2002 |
AMPA and NMDA glutamate receptor trafficking: multiple roads for reaching and leaving the synapse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Endocytosis; Exocytosis; Humans; N-Methylaspartate; Neurons; Protein Transport; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission | 2006 |
Glutamate receptors in neuroinflammatory demyelinating disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Humans; Inflammation; Models, Biological; Models, Chemical; Multiple Sclerosis; N-Methylaspartate; Receptors, Glutamate; Receptors, Kainic Acid | 2006 |
Combined strategies for the discovery of ionotropic glutamate receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anticonvulsants; Drug Discovery; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neuroprotective Agents; Receptors, Glutamate | 2009 |
Dimethyl sulfoxide as an excitatory modulator and its possible role in cancer pain management.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dimethyl Sulfoxide; Glutamic Acid; Humans; N-Methylaspartate; Neoplasms; Pain, Intractable; Quality of Life; Sodium Channels | 2010 |
A role for tumor necrosis factor-α in ischemia and ischemic preconditioning.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Glutamic Acid; Humans; Ischemic Preconditioning; N-Methylaspartate; Neurons; Receptors, Tumor Necrosis Factor; Signal Transduction; Tumor Necrosis Factor-alpha | 2011 |
The developmental stages of synaptic plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Humans; N-Methylaspartate; Nerve Net; Neuronal Plasticity; Phosphoric Monoester Hydrolases; Protein Kinases | 2014 |
Nitric oxide as a regulatory molecule in the processing of the visual stimulus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Gene Expression Regulation; Geniculate Bodies; Glutamine; Humans; N-Methylaspartate; Neurons; Nitric Oxide; Retina; Retinal Ganglion Cells; Signal Transduction; Vision, Ocular; Visual Cortex | 2014 |
The Glutamatergic System in Primary Somatosensory Neurons and Its Involvement in Sensory Input-Dependent Plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ganglia, Sensory; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Neuralgia; Neuronal Plasticity; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Sensory Receptor Cells; Synaptic Transmission | 2017 |
Prion neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Line; Cells, Cultured; Dendritic Spines; Hippocampus; Humans; N-Methylaspartate; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prion Diseases; Prions; PrPC Proteins; Signal Transduction | 2019 |
NMDA and AMPA receptor physiology and role in visceral hypersensitivity: a review.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Humans; N-Methylaspartate; Neuronal Plasticity; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2022 |
Cerebellin-neurexin complexes instructing synapse properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; N-Methylaspartate; Nerve Tissue Proteins; Receptors, AMPA; Synapses | 2023 |
2 trial(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and n-methylaspartate
| Article | Year |
|---|---|
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling.
Topics: Adolescent; Adult; Affect; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infusions, Intravenous; Ketamine; Magnetoencephalography; Male; Middle Aged; Models, Neurological; N-Methylaspartate; Time Factors; Treatment Outcome; Young Adult | 2018 |
Effect of Damaging Rare Mutations in Synapse-Related Gene Sets on Response to Short-term Antipsychotic Medication in Chinese Patients With Schizophrenia: A Randomized Clinical Trial.
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antipsychotic Agents; China; Exome Sequencing; Female; Humans; Male; Mutation; N-Methylaspartate; Psychiatric Status Rating Scales; Schizophrenia; Young Adult | 2018 |
1022 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and n-methylaspartate
| Article | Year |
|---|---|
N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: Acetates; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Hydrogen Bonding; In Vitro Techniques; Isoxazoles; Molecular Structure; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1996 |
Synthesis and enantiopharmacology of new AMPA-kainate receptor agonists.
Topics: Animals; Cerebral Cortex; Convulsants; Excitatory Amino Acid Agonists; In Vitro Techniques; Isoxazoles; Male; Mice; Mice, Inbred DBA; Models, Molecular; Molecular Conformation; Proline; Pyrroles; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Stereoisomerism | 1999 |
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Agonists; HEK293 Cells; Humans; Ligands; Rats; Receptors, AMPA; Synaptosomes; Triazoles | 2019 |
Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.
Topics: Animals; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Cerebellum; CHO Cells; Cricetinae; Cyclic AMP; Cycloleucine; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Inositol Phosphates; Kidney; Ligands; Models, Molecular; Molecular Conformation; Norbornanes; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism | 1998 |
4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues.
Topics: Amino Acids, Acidic; Animals; Brain; Cell Line; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Vitro Techniques; Male; Oocytes; Oxadiazoles; Patch-Clamp Techniques; Potentiometry; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis | 2010 |
Excitatory amino acid-mediated responses and synaptic potentials in medial pontine reticular formation neurons of the rat in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Female; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Pons; Rats; Rats, Inbred Strains; Reticular Formation; Synapses | 1992 |
Modulation of AMPA and NMDA responses in rat spinal dorsal horn neurons by trans-1-aminocyclopentane-1,3-dicarboxylic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Ibotenic Acid; N-Methylaspartate; Neurons; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Spinal Cord | 1992 |
Preferential activation of [3H]phorbol-12,13-dibutyrate binding by AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) in neonatal striatal cell cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Binding Sites; Cells, Cultured; Corpus Striatum; Cycloleucine; Glial Fibrillary Acidic Protein; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344 | 1992 |
Time course of glutamate receptor expression in individual oocytes of Xenopus laevis after injection of rat brain RNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, Glutamate; RNA, Messenger; Xenopus laevis | 1992 |
Excitotoxic lesions of rat basal forebrain: differential effects on choline acetyltransferase in the cortex and amygdala.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Prosencephalon; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1992 |
Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoxazoles; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Oocytes; Propionates; Receptors, Amino Acid; RNA, Messenger; Stereoisomerism; Xenopus laevis | 1992 |
General anaesthetics inhibit the responses induced by glutamate receptor agonists in the mouse cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics; Animals; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Mice; N-Methylaspartate; Receptors, Glutamate | 1992 |
Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Phenols; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1992 |
Activation of a metabotropic excitatory amino acid receptor potentiates A2b adenosine receptor-stimulated cyclic AMP accumulation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotransformation; Cerebral Cortex; Cyclic AMP; Cycloleucine; Female; Guinea Pigs; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Male; N-Methylaspartate; Receptors, Amino Acid; Receptors, Purinergic; Vasodilator Agents | 1992 |
Evidence that [3H]glutamate binding sites are masked by biologically relevant endogenous factor on cell membranes of frog spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cytosol; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Piperazines; Quisqualic Acid; Rana catesbeiana; Spinal Cord | 1992 |
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Cycloleucine; Hemoglobins; Hydroxylamine; Hydroxylamines; Hyperalgesia; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Spinal Cord; Time Factors | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. II. Evidence for functional cooperation and for coexistence on the same axon terminal.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dizocilpine Maleate; Drug Interactions; Hippocampus; Ibotenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Electrophysiology; Evoked Potentials; Female; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Structure-Activity Relationship; Synapses; Xenopus | 1992 |
Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Pertussis Toxin; Quisqualic Acid; Time Factors; Virulence Factors, Bordetella | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
Excitatory amino acid receptors on isolated retinal ganglion cells from the goldfish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retinal Ganglion Cells; Sodium | 1992 |
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neu
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dantrolene; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Verapamil | 1992 |
Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Cations, Divalent; Cells, Cultured; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Magnesium; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains | 1992 |
Evidence for a kynurenate-insensitive glutamate receptor in nucleus tractus solitarii.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aorta; Blood Pressure; Cycloleucine; Electric Stimulation; Female; Heart Rate; Ibotenic Acid; Kynurenic Acid; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Purification of AMPA type glutamate receptor by a spider toxin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cattle; Cerebellum; Chloride Channels; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Liposomes; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Spider Venoms | 1992 |
NMDA treatment and K(+)-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellar Cortex; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1992 |
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
L-glutamate-evoked release of dopamine from synaptosomes of the rat striatum: involvement of AMPA and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical; Synaptosomes | 1992 |
Failure of a protein synthesis inhibitor to modify glutamate receptor-mediated neurotoxicity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anisomycin; Cell Death; Glutamate Decarboxylase; Glutamates; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Ethanol; Female; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oocytes; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Xenopus laevis | 1992 |
Acidic amino acids evoke a smaller [Ca2+]i rise in GABAergic than non-GABAergic hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Ibotenic Acid; Interneurons; Microscopy, Fluorescence; N-Methylaspartate; Rats | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Domoic acid toxicity in rats and mice after intracerebroventricular administration: comparison with excitatory amino acid agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurotoxins; Rats; Rats, Inbred Strains | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Drug Synergism; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Myocardial Contraction; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1992 |
Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Cesium; Colforsin; Glycine; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Peptides; Phorbol Esters; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Tachykinins | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Protein kinase C-mediated enhancement of NMDA currents by metabotropic glutamate receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Calcium; Dose-Response Relationship, Drug; Ibotenic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1992 |
Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Brain Ischemia; Dose-Response Relationship, Drug; Hippocampus; Ibotenic Acid; Male; N-Methylaspartate; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyramidal Tracts; Rats; Rats, Wistar | 1992 |
Pharmacological characterization of non-NMDA subtypes of glutamate receptor in the neonatal rat hemisected spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Methohexital; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Induction of cobalt accumulation by excitatory amino acids within neurons of the hippocampal slice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cobalt; Gerbillinae; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Neurons | 1992 |
The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Drug Synergism; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid | 1992 |
NMDA-induced release of nitric oxide potentiates aspartate overflow from cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Modulation of N-methyl-D-aspartate and (R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) responses of spinal nociceptive neurons by a N-terminal fragment of substance P.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Ibotenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1992 |
Polyamine spider toxins are potent un-competitive antagonists of rat cortex excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Ibotenic Acid; In Vitro Techniques; Indoleacetic Acids; Kainic Acid; Male; N-Methylaspartate; Polyamines; Rats; Receptors, Neurotransmitter; Spider Venoms; Xenopus laevis | 1992 |
Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Cycloleucine; Cytoplasm; Ibotenic Acid; Kinetics; N-Methylaspartate; Neurotoxins; Piperidines; Quisqualic Acid; Receptors, Neurotransmitter | 1991 |
Autoradiographic localisations of glutamatergic ligand binding sites in Xenopus brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain Chemistry; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Xenopus | 1991 |
Arylamine toxins from funnel-web spider (Agelenopsis aperta) venom antagonize N-methyl-D-aspartate receptor function in mammalian brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Cells, Cultured; Cerebellum; Cytosol; Evoked Potentials; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Structure-Activity Relationship; Synapses; Synaptic Transmission | 1991 |
Excitatory amino acids: new tools for old stories or pharmacological subtypes of glutamate receptors: electrophysiological studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Stem; Cerebral Cortex; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Wasp Venoms | 1991 |
Activation of AMPA/kainic acid glutamate receptors in the zona incerta stimulates locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diencephalon; Ibotenic Acid; Injections; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, Neurotransmitter; Substantia Nigra | 1991 |
Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease.
Topics: Adolescent; Adult; Age Factors; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding, Competitive; Caudate Nucleus; Cell Death; Child; Dizocilpine Maleate; Frontal Lobe; Glycine; Humans; Huntington Disease; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Phencyclidine; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1991 |
A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Cycloleucine; Embryo, Mammalian; Glutamates; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1991 |
Transient postnatal increases in excitatory amino acid binding sites in rat ventral mesencephalon.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Corpus Striatum; Glutamates; Ibotenic Acid; Kainic Acid; Mesencephalon; N-Methylaspartate; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Acetylcholine release from the rabbit retina mediated by kainate receptors.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Choline; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rabbits; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina | 1991 |
Neurochemical characterization of excitotoxin lesions in the cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Cerebellum; Evoked Potentials; Glutamates; Glycine; Ibotenic Acid; In Vitro Techniques; Magnesium; Membrane Potentials; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Tetrodotoxin | 1991 |
Excitatory amino acid receptors mediate synaptic responses to visual stimuli in superior colliculus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
Intercellular action of nitric oxide in adult rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Vinpocetine preferentially antagonizes quisqualate/AMPA receptor responses: evidence from release and ligand binding studies.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membranes; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium; Vinca Alkaloids | 1991 |
Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Cerebellum; Electric Conductivity; Glycine; Hydrogen-Ion Concentration; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Protons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1990 |
Glutamate: three meetings but how many receptors? Excitatory Amino Acids 1990: a Fidia Research Foundation Symposium, Padua, Italy, May 21-26, 1990. Excitatory Amino Acid Receptors in the Brain: Functions and Disorders, Montreal, Canada, June 23-24, 1990.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; GTP-Binding Proteins; Ibotenic Acid; Ion Channel Gating; Ion Channels; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction | 1990 |
Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Glycine; Ibotenic Acid; Ion Channels; N-Methylaspartate; Piperidines; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Vasodilator Agents | 1991 |
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P | 1991 |
Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ion Channels; N-Methylaspartate; Neurons; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Comparison of some arthropod toxins and toxin fragments as antagonists of excitatory amino acid-induced excitation of rat spinal neurones.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Arthropod Venoms; Asparagine; Female; Ibotenic Acid; Indoleacetic Acids; Iontophoresis; Microelectrodes; N-Methylaspartate; Neurons; Neurotoxins; Phenols; Phenylacetates; Polyamines; Rats; Rats, Inbred Strains; Spinal Cord; Wasp Venoms | 1991 |
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Ibotenic Acid; Indicators and Reagents; Kainic Acid; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Tetrazoles | 1991 |
Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Novel form of long-term potentiation produced by a K+ channel blocker in the hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Ibotenic Acid; Male; N-Methylaspartate; Potassium Channels; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1991 |
A test of the spine resistance hypothesis for LTP expression.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cold Temperature; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Computer Simulation; Ibotenic Acid; Kainic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ammonia; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; Down-Regulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Liver; Male; N-Methylaspartate; Organ Size; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamus | 1990 |
Cortical neurons containing somatostatin- or parvalbumin-like immunoreactivity are atypically vulnerable to excitotoxic injury in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; Muscle Proteins; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Oxazoles; Parvalbumins; Somatostatin | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Receptor site specificity for the acute effects of beta-N-methylamino-alanine in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Cyanobacteria Toxins; Glutamine; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Kinetics; Male; Mice; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Receptors, Drug; Receptors, N-Methyl-D-Aspartate | 1990 |
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Cats; Electrodes; Glutamates; Glutamic Acid; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Retinal Ganglion Cells | 1990 |
Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Autoradiography; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Neurotransmitter | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Ethanol inhibition of NMDA mediated depolarizations is increased in the presence of Mg2+.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Ethanol; Female; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains | 1991 |
A quantitative analysis of the effects of excitatory neurotoxins on retinal ganglion cells in the chick.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Chickens; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Retina; Retinal Ganglion Cells; Vitreous Body | 1990 |
Philanthotoxin blocks quisqualate-, AMPA- and kainate-, but not NMDA-, induced excitation of rat brainstem neurones in vivo.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Female; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quisqualic Acid; Rats; Rats, Inbred Strains; Wasp Venoms | 1990 |
Effects of hypoxia and hypoglycaemia on DC potentials recorded from the gerbil hippocampus in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cell Hypoxia; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Hypoglycemia; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium Channels; Drug Antagonism; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Mice; N-Methylaspartate; Neurons; Nifedipine; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Brain; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Male; N-Methylaspartate; Pipecolic Acids; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism | 1990 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of cerebellar granule cells in culture: effect of kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Dizocilpine Maleate; DNA; Electric Stimulation; Glutamine; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates | 1989 |
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dipeptides; Electric Stimulation; Female; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neural Conduction; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Hypoglycemia; Ibotenic Acid; Insulin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using L-[3H]glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Software; Tritium | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
Is L-glutamate a neurotransmitter of baroreceptor information in the nucleus of the tractus solitarius?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Blood Pressure; Electric Stimulation; Female; Glutamates; Heart Rate; Ibotenic Acid; Kynurenic Acid; Medulla Oblongata; N-Methylaspartate; Neurotransmitter Agents; Pressoreceptors; Rats; Reflex; Sensory Receptor Cells; Xanthurenates | 1989 |
AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia innominata/lateral preoptic area.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Oxazoles; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Substantia Innominata | 1989 |
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1985 |
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1986 |
Excitatory amino acid receptors and ischemic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kainic Acid; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1987 |
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc | 1987 |
AMPA is a powerful neurotoxin in the chicken retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chickens; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Ibotenic Acid; Injections; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Oxadiazoles; Oxazoles; Quisqualic Acid; Retina; Retinal Ganglion Cells; Vitreous Body | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Maturational changes in retinal excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Chick Embryo; Embryonic and Fetal Development; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Glutamates; Glutamine; Ibotenic Acid; Injections; Kainic Acid; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1988 |
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Lithium; Lithium Chloride; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1988 |
Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Aspartic Acid; Basal Ganglia; Brain; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata; Synaptic Transmission | 1988 |
Glutamate receptors of ganglion cells in the rabbit retina: evidence for glutamate as a bipolar cell transmitter.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Light; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells | 1988 |
Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Stem; Cells, Cultured; Embryo, Mammalian; Glutamates; Ibotenic Acid; N-Methylaspartate; Oxazoles; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1983 |
L-glutamate-induced changes in intracellular calcium oscillation frequency through non-classical glutamate receptor binding in cultured rat myocardial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Intracellular Fluid; Kainic Acid; Myocardium; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy | 1995 |
Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Rats; Receptors, Amino Acid; Riluzole; Thiazoles | 1995 |
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Male; Microdialysis; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Serine | 1993 |
Growth conditions differentially regulate the expression of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor subunits in cultured neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Base Sequence; Calcium; Cell Division; Cells, Cultured; Cerebellum; Gene Expression Regulation; Kinetics; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Neurons; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Potassium; Rats; Receptors, AMPA; Receptors, Glutamate; RNA, Messenger | 1993 |
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Administration Schedule; Injections, Intraperitoneal; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reperfusion | 1993 |
Functional kainate-selective glutamate receptors in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Embryo, Mammalian; Hippocampus; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P | 1993 |
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Female; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Lanthanum; N-Methylaspartate; Neurons; Neurotoxins; Photometry; Potassium; Pregnancy; Presynaptic Terminals; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
[Future treatment of stroke. Brain injury can be reduced with drugs].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium Channel Blockers; Cell Death; Cerebral Infarction; Humans; Microcirculation; N-Methylaspartate; Neuroglia; Time Factors | 1993 |
Induction of cerebellar long-term depression in culture requires postsynaptic action of sodium ions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Electrophysiology; Embryo, Mammalian; Evoked Potentials; Mice; N-Methylaspartate; Neuronal Plasticity; Neurons; Neurotoxins; Picrotoxin; Quisqualic Acid; Receptors, AMPA; Sodium; Synapses; Tetrodotoxin; Veratridine | 1993 |
Simultaneous local pressure microejection of excitatory amino acids and field potential recording with a single micropipette in the hippocampal slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Hippocampus; In Vitro Techniques; Injections, Jet; Iontophoresis; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
Different functions of spinal 5-HT1A and 5-HT2 receptor subtypes in modulating behaviour induced by excitatory amino acid receptor agonists in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; N-Methylaspartate; Receptors, Serotonin; Spinal Cord | 1993 |
Effect of glutamate receptor antagonists on N-methyl-D-aspartate- and (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced convulsant effects in mice and rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Excitatory Amino Acid Antagonists; Female; Male; Mice; N-Methylaspartate; Rats; Rats, Wistar | 1993 |
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Membrane currents evoked by excitatory amino acid agonists in ON bipolar cells of the mudpuppy retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Cadmium; Cell Membrane; Cobalt; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Necturus maculosus; Neurotransmitter Agents; Receptors, Amino Acid; Retina | 1993 |
Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Glutamates; Glutamic Acid; Hippocampus; Homeostasis; Kinetics; Lymphotoxin-alpha; N-Methylaspartate; Neurons; Neurotoxins; Rats; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar | 1993 |
Polyamine modulation of excitatory amino acid responses in the rat cortical wedge.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Biogenic Polyamines; Cerebral Cortex; Epilepsy; In Vitro Techniques; Male; Membrane Potentials; Models, Biological; N-Methylaspartate; Rats; Rats, Wistar; Spermine | 1993 |
Glutamate-evoked release of arachidonic acid from mouse brain astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurotoxins; Organ Specificity; Quisqualic Acid; Receptors, Glutamate; Time Factors; Tritium | 1994 |
Ionotropic glutamate receptor types leading to adenosine-mediated inhibition of electrically evoked [3H]-noradrenaline release in rabbit brain cortex slices.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Female; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Rabbits; Receptors, Glutamate | 1993 |
Differential effects of NBQX on the distal and local toxicity of glutamate agonists administered intra-hippocampally.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Diazepam; Hippocampus; Injections; Kainic Acid; Limbic System; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate | 1993 |
Delayed treatment with AMPA, but not NMDA, antagonists reduces neocortical infarction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Male; N-Methylaspartate; Pilot Projects; Quinoxalines; Rats; Rats, Inbred SHR; Sodium Chloride | 1994 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
The lateral hypothalamus: a primary site mediating excitatory amino acid-elicited eating.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Feeding Behavior; Glutamates; Glutamic Acid; Hypothalamic Area, Lateral; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley | 1993 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Metabotropic excitatory amino acid receptor agonists selectively potentiate behavioral effects induced by ionotropic excitatory amino acid receptor agonists in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Drug Synergism; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Pentylenetetrazole; Receptors, Glutamate; Seizures | 1993 |
Carbachol can potentiate N-methyl-D-aspartate responses in the rat hippocampus by a staurosporine and thapsigargin-insensitive mechanism.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Drug Synergism; Female; Hippocampus; In Vitro Techniques; N-Methylaspartate; Protein Kinase C; Rats; Receptors, Muscarinic; Staurosporine; Terpenes; Tetrodotoxin; Thapsigargin | 1993 |
Stimulation of N-methyl-D-aspartate receptors in the rat nucleus reticularis thalami suppresses somatosensory evoked potentials.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Male; Microinjections; N-Methylaspartate; Nerve Fibers; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thalamic Nuclei | 1994 |
Dexamethasone potentiates NMDA receptor-mediated neuronal injury in the postnatal rat.
Topics: Aldosterone; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Autoradiography; Blood Glucose; Brain; Dexamethasone; Electron Transport Complex IV; Glutamates; Glutamic Acid; Kainic Acid; Metyrapone; N-Methylaspartate; Neurotransmitter Agents; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Ischemia; Cochlea; Cochlear Microphonic Potentials; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Male; N-Methylaspartate; Neurons, Afferent; Neurotransmitter Agents; Perfusion; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electrophysiology; Glutamates; Glutamic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1994 |
Evidence that GYKI 52466, a novel non-NMDA antagonist enhances the decay of kainate-induced current in cultured chicken cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines | 1994 |
Excitatory amino acid-induced excitation of dopamine-containing neurons in the rat substantia nigra: modulation by kynurenic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electrophysiology; Extracellular Space; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1994 |
Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Cricetinae; Cyclic AMP; Glycine; Hydrolysis; Kainic Acid; Kidney; Male; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1994 |
Cyclothiazide selectively potentiates AMPA- and kainate-induced [3H]norepinephrine release from rat hippocampal slices.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Drug Synergism; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tritium; Veratridine | 1994 |
The effects of BTS 54,505, a metabolite of sibutramine, on monoamine and excitatory amino acid-evoked responses in the rat dorsolateral geniculate nucleus in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclobutanes; Evoked Potentials, Visual; Geniculate Bodies; Iontophoresis; Male; N-Methylaspartate; Norepinephrine; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serotonin | 1994 |
Intrathecal co-administration of morphine and excitatory amino acid agonists produce differential effects on the tail-flick of intact and spinal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Catheters, Indwelling; Decerebrate State; Drug Synergism; Injections, Spinal; Male; Morphine; N-Methylaspartate; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Reference Values; Statistics as Topic | 1994 |
Penile erection and yawning induced by paraventricular NMDA injection in male rats are mediated by oxytocin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dopamine; Injections; Injections, Intraventricular; Male; N-Methylaspartate; Neurotoxins; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Synaptic Transmission; Yawning | 1994 |
Effect of local infusion of glutamate analogues into the nucleus accumbens of rats: an electrochemical and behavioural study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electrochemistry; Glutamates; Infusions, Parenteral; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Nomifensine; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Reserpine; Tetrodotoxin | 1994 |
Effects of nitric oxide synthase inhibitors on N-methyl-D-aspartate-induced phase delay of circadian rhythm of neuronal activity in the rat suprachiasmatic nucleus in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Circadian Rhythm; In Vitro Techniques; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Stereoisomerism; Suprachiasmatic Nucleus | 1994 |
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin | 1994 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline protects against both AMPA and kainate-induced lesions in rat striatum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 1994 |
AMPA receptors have an equal role in spinal nociceptive and non-nociceptive transmission.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Iontophoresis; Male; N-Methylaspartate; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Synaptic Transmission | 1994 |
Discrimination by added ions of ligands at ionotropic excitatory amino acid receptors insensitive to N-methyl-D-aspartate in rat brain using membrane binding techniques.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anions; Brain; Kainic Acid; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Wistar; Receptors, Amino Acid; Sulfhydryl Reagents; Synaptic Membranes; Thiocyanates | 1994 |
Glutamate receptor-driven activation of transcription factors in primary neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Base Sequence; Binding Sites; Cell Nucleus; Cell Survival; Cells, Cultured; Cycloleucine; Embryo, Mammalian; Gene Expression; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Mice; Molecular Sequence Data; N-Methylaspartate; Neurons; Proto-Oncogene Proteins; Proto-Oncogenes; Quisqualic Acid; Rats; Receptors, Glutamate; Transcription Factors | 1994 |
N-methyl-D-aspartate induces phase shifts in circadian rhythm of neuronal activity of rat SCN in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Dizocilpine Maleate; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Neurons; Neuropeptide Y; Quinoxalines; Rats; Rats, Wistar; Suprachiasmatic Nucleus | 1994 |
The NO-cGMP pathway in neonatal rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Biomarkers; Cyclic GMP; Female; Glutathione; Male; N-Methylaspartate; NADPH Dehydrogenase; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Nitroso Compounds; Pain; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; S-Nitrosoglutathione; Second Messenger Systems; Signal Transduction; Spinal Cord | 1994 |
Possible role of glutamatergic neurotransmission in regulating ethanol-evoked brain ascorbate release.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ascorbic Acid; Brain Chemistry; Dicarboxylic Acids; Electrophysiology; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Injections, Intraventricular; Kainic Acid; Male; Microelectrodes; N-Methylaspartate; Neostriatum; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
Chondroitin sulfate proteoglycans protect cultured rat's cortical and hippocampal neurons from delayed cell death induced by excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Chondroitin Sulfates; Hippocampus; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Proteoglycans; Rats; Rats, Sprague-Dawley | 1994 |
Effects of L-glutamate on the responses to nerve stimulation in rat isolated atria.
Topics: Adrenergic Fibers; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Atrial Function; Electric Stimulation; Female; Glutamates; Glutamic Acid; Heart Atria; Heart Rate; In Vitro Techniques; Kainic Acid; Male; Muscarinic Antagonists; N-Methylaspartate; Norepinephrine; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar | 1994 |
A comparison of intravenous NBQX and GYKI 53655 as AMPA antagonists in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Hot Temperature; Injections, Intravenous; Iontophoresis; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord | 1994 |
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cytosol; Dizocilpine Maleate; Fetus; Glucose; Glutamic Acid; Glycine; Hypothermia, Induced; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurons | 1994 |
Interactions between N-acetylaspartylglutamate and AMPA, kainate, and NMDA binding sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Dipeptides; Drug Interactions; Kainic Acid; N-Methylaspartate; Prosencephalon; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tritium | 1994 |
Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands.
Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glycine; Hydrogen Bonding; Isoxazoles; Ligands; Molecular Conformation; Molecular Structure; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship; Thermodynamics | 1994 |
Comparative patch clamp studies on the kinetics and selectivity of glutamate receptor antagonism by 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) and 1-(4-amino-phenyl)-4-methyl-7,8-methyl-endioxyl-5H-2,3-benzodiaze pine (GYKI 52466).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Superior Colliculi | 1994 |
Release of the nitric oxide precursor, arginine, from the thalamus upon sensory afferent stimulation, and its effect on thalamic neurons in vivo.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Glutamic Acid; Male; N-Methylaspartate; Neurons; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar; Synaptic Transmission; Thalamus; Vibrissae | 1994 |
Basal forebrain cholinergic neurons are selectively vulnerable to AMPA/kainate receptor-mediated neurotoxicity.
Topics: Acetylcholine; Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Cells, Cultured; Choline O-Acetyltransferase; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Prosencephalon; Receptors, AMPA; Receptors, Kainic Acid | 1994 |
Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P.
Topics: Acetaminophen; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Substance P | 1994 |
Intrathecal excitatory amino acid (EAA) agonists increase tail flick latencies (TFLs) of spinal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cordotomy; Excitatory Amino Acids; Injections, Spinal; Male; N-Methylaspartate; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time | 1994 |
Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons.
Topics: Acute Disease; Afferent Pathways; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Cycloleucine; Inflammation; Knee Joint; Male; N-Methylaspartate; Neurons; Pain; Pressure; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
NMDA and carbachol but not AMPA affect differently the release of [3H]GABA in striosome- and matrix-enriched areas of the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Carbachol; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; N-Methylaspartate; Neostriatum; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1994 |
Developmental alterations in NMDA receptor-mediated [Ca2+]i elevation in substantia gelatinosa neurons of neonatal rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Capsaicin; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substantia Gelatinosa | 1994 |
Spinal mediators of hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calcium; Cycloleucine; Disease Models, Animal; Excitatory Amino Acids; Hot Temperature; Hyperalgesia; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Afferent; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stress, Mechanical | 1994 |
Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Fetus; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Potassium Chloride; Quisqualic Acid | 1994 |
Role of metabotropic glutamate receptors in ventrolateral medulla of hypertensive rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cycloleucine; Heart Rate; Hypertension; Male; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Sympathetic Nervous System | 1994 |
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ethanol; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Naloxone; Nucleus Accumbens; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 1994 |
Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Phosphopyruvate Hydratase; Propofol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 1994 |
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission | 1994 |
Thyrotropin-releasing hormone enhances excitatory postsynaptic potentials in neocortical neurons of the rat in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Thyrotropin-Releasing Hormone | 1994 |
NMDA and non-NMDA receptor-mediated release of [3H]GABA from granule cell dendrites of rat olfactory bulb.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glycine; Granulocytes; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1995 |
Potentiation of synaptic transmission in the rat hippocampal slice by exogenous L-glutamate and selective L-glutamate receptor subtype agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Iontophoresis; N-Methylaspartate; Nerve Fibers; Neurotoxins; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Synapses; Synaptic Transmission | 1994 |
NMDA-dependent nitric oxide release in the hippocampus in vivo: interactions with noradrenaline.
Topics: Adrenergic alpha-1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Benzylamines; Hippocampus; Male; Microdialysis; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Rats; Rats, Wistar | 1994 |
Aluminium reduces glutamate-activated currents of rat hippocampal neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aluminum; Animals; Electric Conductivity; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Osmolar Concentration; Rats; Rats, Wistar | 1994 |
NMDA, kainate, and AMPA depolarize nondopamine neurons in the rat ventral tegmentum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 1995 |
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles | 1994 |
Taurine release from mouse hippocampal slices: effects of glutamatergic substances and hypoxia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Nitrogen; Oxygen; Potassium; Quisqualic Acid; Taurine | 1994 |
Intracerebral microdialysis combined with recording of extracellular field potential: a novel method for investigation of depolarizing drugs in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Polarity; Electroencephalography; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Neostriatum; Rats; Rats, Sprague-Dawley | 1994 |
A role for non-NMDA excitatory amino acid receptors in regulating the basal activity of rat globus pallidus neurons and their activation by the subthalamic nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Extracellular Space; GABA-A Receptor Antagonists; Globus Pallidus; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Thalamic Nuclei | 1994 |
Release of [3H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca2+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Nicotinic Acids; Nipecotic Acids; Oximes; Quisqualic Acid; Retina; Tritium | 1994 |
Exposure of rat spinal neurones to NMDA, AMPA and kainate produces only short-term enhancements of responses to noxious and non-noxious stimuli.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Hot Temperature; Kainic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Pain; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Time Factors | 1994 |
Calcium dependence of glutamate receptor-evoked alkaline shifts in hippocampus.
Topics: Alkalies; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Extracellular Space; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Potassium; Rats; Receptors, Glutamate | 1994 |
Modulation of neuropeptide FF release from rat spinal cord slices by glutamate. Involvement of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Membranes; N-Methylaspartate; Neuropeptides; Neurotoxins; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Presynaptic ionotropic glutamate receptors modulate in vivo release and metabolism of striatal dopamine, noradrenaline, and 5-hydroxytryptamine: involvement of both NMDA and AMPA/kainate subtypes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serotonin | 1994 |
The subthalamo-nigral pathway regulates movement and concomitant acetylcholinesterase release from the substantia nigra.
Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Guinea Pigs; Ketamine; Male; Motor Activity; N-Methylaspartate; Neural Pathways; Substantia Nigra; Urethane | 1994 |
Neuroprotective effect of free radical scavengers on beta-N-oxalylamino-L-alanine (BOAA)-induced neuronal damage in rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Free Radical Scavengers; Hippocampus; Kainic Acid; Male; Motor Neuron Disease; N-Methylaspartate; Neurons; Rats; Rats, Wistar | 1994 |
Involvement of free radicals in excitotoxicity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Death; Cells, Cultured; Cyclic N-Oxides; Dizocilpine Maleate; Electrophysiology; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Kainic Acid; Male; N-Methylaspartate; Neurons; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1995 |
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1995 |
Effects of the epileptogenic agent strychnine on membrane currents elicited by agonists of the NMDA and non-NMDA receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Glycine; Ion Channels; Kainic Acid; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Xenopus laevis | 1995 |
Felbamate selectively blocks in vitro hippocampal kainate-induced irreversible electrical changes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; Felbamate; Hippocampus; Kainic Acid; Kynurenic Acid; Lamotrigine; Male; N-Methylaspartate; Pentobarbital; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar; Triazines | 1995 |
Changes of extracellular calcium concentration induced by application of excitatory amino acids in the human neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Humans; In Vitro Techniques; Injections; Male; Membrane Potentials; N-Methylaspartate | 1995 |
Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Antibodies, Monoclonal; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acids; Fetus; Glutamic Acid; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Kinetics; N-Methylaspartate; Nerve Degeneration; Nerve Growth Factors; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Dopamine enhances glutamate-activated currents in spinal motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Base Sequence; Benzazepines; Chick Embryo; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; Glutamic Acid; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Molecular Sequence Data; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Polymerase Chain Reaction; Receptors, Dopamine D1; RNA, Messenger; Spinal Cord; Time Factors | 1995 |
Induction of calpain-mediated spectrin fragments by pathogenic treatments in long-term hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Calpain; Culture Techniques; Hippocampus; Hydrolysis; Molecular Sequence Data; N-Methylaspartate; Peptide Fragments; Rats; Receptors, AMPA; Spectrin | 1995 |
Single glutamate channels in CA1 pyramidal neurones after transient ischaemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Gerbillinae; Kainic Acid; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Receptors, Glutamate; Time Factors | 1995 |
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcimycin; Cerebral Cortex; Child; Cycloleucine; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Male; Middle Aged; N-Methylaspartate; Phosphatidylinositols; Quisqualic Acid; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrodotoxin | 1995 |
On the linkage between AMPA and NMDA receptor-mediated EPSPs in homosynaptic long-term depression in the hippocampal CA1 region of young rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 1995 |
Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Communication; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Fetus; Glutamic Acid; Kinetics; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins | 1995 |
Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/Kainate receptors in organotypic hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Cell Differentiation; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1995 |
Regulation of spontaneous phasic firing of rat supraoptic vasopressin neurones in vivo by glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Kainic Acid; Male; N-Methylaspartate; Oxytocin; Rats; Receptors, Glutamate; Supraoptic Nucleus; Vasopressins | 1995 |
Characterization of voltage-sensitive Ca2+ channels activated by presynaptic glutamate receptor stimulation in hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Dopamine; Hippocampus; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; N-Methylaspartate; Receptors, Glutamate; Receptors, Presynaptic; Signal Transduction; Synaptosomes | 1995 |
1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Memory; N-Methylaspartate; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1995 |
Developmental change of the potentiation of NMDA response by spermine.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Electrophysiology; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Nystatin; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spermine; Ventromedial Hypothalamic Nucleus | 1995 |
Long-term enhancement of dopamine release by high frequency tetanic stimulation via a N-methyl-D-aspartate-receptor-mediated pathway in rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neostriatum; Nerve Endings; Potassium Chloride; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cerebellum; Cobalt; Concanavalin A; Excitatory Amino Acids; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Wheat Germ Agglutinins | 1995 |
Independent mechanisms for long-term depression of AMPA and NMDA responses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Artifacts; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Excitatory amino acid receptor ligands: asymmetric synthesis, absolute stereochemistry and pharmacology of (R)- and (S)-homoibotenic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Radioligand Assay; Rats; Receptors, Glutamate; Stereoisomerism; Structure-Activity Relationship | 1995 |
Effects of excitatory amino acid lesions upon neurokinin B and acetylcholine neurons in the nucleus basalis of the rat.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; In Situ Hybridization; Male; N-Methylaspartate; Neurokinin B; Neurons; Rats; Rats, Inbred F344; Substantia Innominata | 1995 |
GFAP-positive hippocampal astrocytes in situ respond to glutamatergic neuroligands with increases in [Ca2+]i.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Rats | 1995 |
Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Cattle; Cells, Cultured; Cerebellum; Cyclic GMP; Guanylate Cyclase; Hippocampus; In Vitro Techniques; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar | 1995 |
Synchrony measures for biological neural networks.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Computer Simulation; Cybernetics; Hippocampus; Humans; In Vitro Techniques; Models, Neurological; N-Methylaspartate; Nerve Net; Periodicity | 1995 |
Ca2+ permeable AMPA/kainate channels permit rapid injurious Ca2+ entry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Count; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Receptors, AMPA; Receptors, Kainic Acid | 1995 |
Effects of nitric oxide availability on responses of spinal wide dynamic range neurons to excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Penicillamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; S-Nitroso-N-Acetylpenicillamine; Spinal Canal | 1995 |
Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Glutamic Acid; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1995 |
Pressor responses to stimulation of non-NMDA receptors in the superficial laminae of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Blood Pressure; Cats; Decerebrate State; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Microinjections; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Spinal Cord | 1995 |
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, but not N-methyl-D-aspartate, activates mitogen-activated protein kinase through G-protein beta gamma subunits in rat cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Enzyme Activation; Excitatory Amino Acid Agonists; Fetus; GTP-Binding Proteins; Macromolecular Substances; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; N-Methylaspartate; Neurons; Pertussis Toxin; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Virulence Factors, Bordetella | 1995 |
Schedule-controlled behavioral effects of the selective 2-amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic acid antagonist LY293558 in pigeons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Columbidae; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoquinolines; Isoxazoles; Male; N-Methylaspartate; Propionates; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Stereoisomerism; Tetrazoles | 1995 |
Modulation of excitatory amino acid responses by tachykinins and selective tachykinin receptor agonists in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acids; Male; N-Methylaspartate; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Tachykinin; Spinal Cord; Substance P; Tachykinins | 1995 |
NMDA and non-NMDA receptors contribute to synaptic transmission between the medial geniculate body and the lateral nucleus of the amygdala.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Electric Stimulation; Glutamic Acid; Male; Memory; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Modulation by ionotropic excitatory amino acids and potassium of (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylic acid-stimulated phosphoinositide hydrolysis in mouse cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cerebellum; Cycloleucine; Drug Synergism; Excitatory Amino Acids; Hydrolysis; Magnesium; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurons; Phosphatidylinositols; Potassium; Receptors, Amino Acid; Receptors, Metabotropic Glutamate | 1995 |
Basic fibroblast growth factor selectively increases AMPA-receptor subunit GluR1 protein level and differentially modulates Ca2+ responses to AMPA and NMDA in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Fibroblast Growth Factor 2; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cerebral Cortex; Diuretics; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1993 |
N-methyl-D-aspartate- and non-N-methyl-D-aspartate-evoked adenosine release from rat cortical slices: distinct purinergic sources and mechanisms of release.
Topics: 5'-Nucleotidase; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Nucleosides; Purines; Rats | 1993 |
Dipsogenic effects of excitatory amino acid agonists in pigeons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Columbidae; Drinking; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1993 |
Binding of [3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and [3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cell Membrane; Dizocilpine Maleate; Female; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Receptors, Glutamate; Spermidine; Thiocyanates; Tissue Distribution | 1993 |
Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cycloleucine; Glycine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Glutamate; Spinal Cord; Thalamus | 1993 |
N-methyl-D-aspartate induces regular firing patterns in the cat lateral habenula in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Ibotenic Acid; Iontophoresis; Kainic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Stereotaxic Techniques; Thalamus | 1993 |
Norbinaltorphimine protection against N-methyl-D-aspartic acid-induced convulsions and mortality.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Binding, Competitive; Brain; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Naltrexone; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Enflurane inhibits NMDA, AMPA, and kainate-induced currents in Xenopus oocytes expressing mouse and human brain mRNA.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Enflurane; Female; Humans; Ibotenic Acid; Ion Channels; Kainic Acid; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Oocytes; Receptors, Glutamate; RNA, Messenger; Species Specificity; Xenopus laevis | 1993 |
(R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors mediate a calcium-dependent inhibition of the metabotropic glutamate receptor-stimulated formation of inositol 1,4,5-trisphosphate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol 1,4,5-Trisphosphate; N-Methylaspartate; Protein Kinases; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Non-NMDA-mediated transmission of somatosensory-evoked potentials in the rat thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Anticonvulsants; Electric Stimulation; Evoked Potentials, Somatosensory; Glycine; Ibotenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stereotaxic Techniques; Synaptic Transmission; Thalamic Nuclei | 1993 |
Are chimeric kainate/N-methyl-D-aspartate receptors expressed in Xenopus oocytes from mammalian and amphibian RNA?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Female; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oocytes; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; RNA; Xenopus | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental dopamine neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 1993 |
Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electrophysiology; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
Effects of phencyclidine on spontaneous and excitatory amino acid-induced activity of ventral tegmental dopamine neurons: an extracellular in vitro study.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dopamine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 1993 |
Medium-dependent dissociation of cytotoxic and GABA-releasing effects of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and kainate in rat cortical cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1993 |
Stimulation by glutamate receptors of arachidonic acid release depends on the Na+/Ca2+ exchanger in neuronal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Calcium; Carrier Proteins; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Ibotenic Acid; Mice; N-Methylaspartate; Neurons; Phospholipases A; Phospholipases A2; Protein Kinase C; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Calcium Exchanger; Veratridine; Virulence Factors, Bordetella | 1993 |
Induction of astrocyte glutamine synthetase activity by the Lathyrus toxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (beta-L-ODAP).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Animals, Newborn; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Glutamate-Ammonia Ligase; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Reconstitution of glutamate receptor proteins purified from Xenopus central nervous system into artificial bilayers.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chromatography, Affinity; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Lipid Bilayers; N-Methylaspartate; Receptors, Glutamate; Xenopus | 1993 |
Ionotropic non-N-methyl-D-aspartate agonists induce retraction of dendritic spinules from retinal horizontal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Carps; Cell Movement; Cyclopentanes; Dendrites; Ibotenic Acid; N-Methylaspartate; Quisqualic Acid; Receptors, Neurotransmitter; Retina | 1993 |
NMDA receptors mediate neuronal burst firing in rat somatosensory cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1993 |
Lateral hypothalamic injections of glutamate, kainic acid, D,L-alpha-amino-3-hydroxy-5-methyl-isoxazole propionic acid or N-methyl-D-aspartic acid rapidly elicit intense transient eating in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Eating; Glutamates; Glutamic Acid; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Kainate toxicity in energy-compromised rat hippocampal slices: differences between oxygen and glucose deprivation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Electrophysiology; Energy Metabolism; Evoked Potentials; Glucose; Hippocampus; Hypoxia, Brain; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
AMPA and NMDA binding sites in the hypothalamic lateral tuberal nucleus: implications for Huntington's disease.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 1993 |
An analysis of synaptic transmission to motoneurones in the cat spinal cord using a new selective receptor blocker.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cats; Electrophysiology; Female; Ibotenic Acid; Male; Motor Neurons; N-Methylaspartate; Spinal Cord; Synapses; Synaptic Transmission | 1993 |
N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Conotoxins; Dendrites; Evoked Potentials; Ibotenic Acid; Magnesium; Membrane Potentials; Mollusk Venoms; N-Methylaspartate; Neurons; Peptides, Cyclic; Pyramidal Tracts; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Ibotenic Acid; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Spinal Cord; Stereoisomerism; Thalamus | 1993 |
Excitatory amino acid-induced slow biphasic responses of free intracellular calcium in human neuroblastoma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cycloleucine; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Tumor Cells, Cultured | 1993 |
Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Evoked Potentials; Glucose; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pipecolic Acids; Pyramidal Tracts; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tritium | 1993 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Spinal Cord | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Pentamidine, an inhibitor of spinal flexor reflexes in rats, is a potent N-methyl-D-aspartate (NMDA) antagonist in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Drug Interactions; Electromyography; H-Reflex; Ibotenic Acid; Injections, Spinal; Male; N-Methylaspartate; Pentamidine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Tibial Nerve | 1993 |
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Dextromethorphan blocks N-methyl-D-aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amlodipine; Animals; Barium; Calcium Channels; Cells, Cultured; Cerebral Cortex; Dextromethorphan; Electrophysiology; Female; Kainic Acid; N-Methylaspartate; Neurons; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channels | 1993 |
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rana pipiens; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Tetrodotoxin; Thalamus | 1993 |
Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Cats; Caudate Nucleus; Dopamine; Ergolines; In Vitro Techniques; N-Methylaspartate; Neostriatum; Quinpirole; Quisqualic Acid; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Interactions between excitatory amino acids and tachykinins and long-term changes of synaptic responses in the rat spinal dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Rats; Spinal Cord; Substance P; Synapses; Tetrodotoxin | 1993 |
Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cycloleucine; Electromyography; Glutamates; Glutamic Acid; Kainic Acid; Male; Muscles; N-Methylaspartate; Parkinson Disease; Rats; Receptors, Glutamate | 1993 |
Opioid-glutamate interactions in rat locus coeruleus neurons.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission | 1993 |
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin | 1996 |
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission | 1996 |
Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biotransformation; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Extracellular Space; Mice; N-Methylaspartate; Nerve Degeneration; Neuroglia; Neurons; Receptors, Metabotropic Glutamate | 1995 |
Stimulation of serotonin release in the rat brain cortex by activation of ionotropic glutamate receptors and its modulation via alpha 2-heteroreceptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Glutamate; Serotonin | 1995 |
Pharmacology of metabotropic glutamate receptor-mediated enhancement of responses to excitatory and inhibitory amino acids on rat spinal neurones in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cycloleucine; Electrophoresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Spinal Cord | 1995 |
In vitro and in vivo antagonism of AMPA receptor activation by (3S, 4aR, 6R, 8aR)-6-[2-(1(2)H-tetrazole-5-yl) ethyl] decahydroisoquinoline-3-carboxylic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Isoquinolines; Male; Mice; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles; Time Factors | 1995 |
Excitatory amino acid-induced currents in rat septal cholinergic neurons in culture.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cholinergic Fibers; Excitatory Amino Acids; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Septal Nuclei; Zinc | 1995 |
Muscarinic depression of excitatory synaptic transmission mediated by the presynaptic M3 receptors in the rat neostriatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Depression, Chemical; Electric Stimulation; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Presynaptic; Synaptic Transmission | 1995 |
Central stimulation of oxytocin release in the lactating rat by N-methyl-D-aspartate: requirement for coactivation through non-NMDA glutamate receptors or the glycine coagonist site.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; Lactation; N-Methylaspartate; Oxytocin; Radioimmunoassay; Rats; Receptors, Glutamate; Receptors, Glycine | 1995 |
Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Kainic Acid; Mice; Molecular Structure; N-Methylaspartate; Neuroprotective Agents; Organophosphonates; Quinolones; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Xenopus | 1996 |
Differentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Convulsants; Cues; Discrimination Learning; Discrimination, Psychological; Excitatory Amino Acid Agonists; Isoxazoles; Ligands; Male; Mice; N-Methylaspartate; Propionates; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures | 1995 |
The complementary nature of long-term depression and potentiation revealed by dual component excitatory postsynaptic potentials in hippocampal slices from young rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1995 |
Regulation of N-methyl-D-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Cyclopentanes; GABA Agonists; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microscopy, Video; Motor Activity; N-Methylaspartate; Neostriatum; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reference Values | 1996 |
The effects of (-)- and (+)-beta-cyclazocine on NMDA-evoked responses and NMDA-mediated cell damage in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cyclazocine; Kainic Acid; Microchemistry; N-Methylaspartate; Neuroprotective Agents; Potassium; Pyramidal Cells; Rats; Rats, Wistar; Spectrometry, Fluorescence; Stereoisomerism | 1995 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Hippocampal CA1 lacunosum-moleculare interneurons: comparison of effects of anoxia on excitatory and inhibitory postsynaptic currents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Glutamic Acid; Hippocampus; Hypoxia, Brain; Interneurons; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission | 1995 |
Effects of repeated cold stress on aversive responses produced by intrathecal excitatory amino acids in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cold Temperature; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Stress, Psychological | 1995 |
In vivo electrochemical studies of the dynamic effects of locally applied excitatory amino acids in the striatum of the anesthetized rat.
Topics: Adolescent; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Cricetinae; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Humans; Kainic Acid; Male; N-Methylaspartate; Oxidation-Reduction; Potassium; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1996 |
Effects of decahydroisoquinoline-3-carboxylic acid monohydrate, a novel AMPA receptor antagonist, on glutamate-induced CA2+ responses and neurotoxicity in rat cortical and cerebellar granule neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamic Acid; Isoquinolines; Kainic Acid; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles | 1995 |
Characterization of excitatory amino acid modulation of dopamine release in the prefrontal cortex of conscious rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Consciousness; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 1996 |
Axotomized neonatal motoneurons overexpressing the bcl2 proto-oncogene retain functional electrophysiological properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Axons; Denervation; Facial Nerve; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Microscopy, Electron; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; Time Factors; Vasopressins | 1996 |
Decreased gonadotropin-releasing hormone neurosecretory response to glutamate agonists in middle-aged female rats on proestrus afternoon: a possible role in reproductive aging?
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arcuate Nucleus of Hypothalamus; Base Sequence; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Kainic Acid; Luteinizing Hormone; Median Eminence; Molecular Sequence Data; N-Methylaspartate; Preoptic Area; Proestrus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1996 |
Excitatory amino acid-induced neuronal cell death in rat cerebellar granule cell cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellum; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
Septal and hippocampal glutamate receptors modulate the output of acetylcholine in hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Septal Nuclei | 1996 |
Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carboxylic Acids; Cerebral Cortex; Isoquinolines; Kainic Acid; Kinetics; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Radioligand Assay; Rats; Receptors, AMPA; Structure-Activity Relationship; Tetrazoles; Tritium | 1996 |
Photoperiod regulates the LH response to central glutamatergic stimulation in the male Syrian hamster.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Gonadotropin-Releasing Hormone; Immunohistochemistry; Injections, Intraventricular; Luteinizing Hormone; Male; Mesocricetus; N-Methylaspartate; Photoperiod; Proto-Oncogene Proteins c-fos; Radioimmunoassay; Reproduction | 1993 |
Effects of excitatory amino acid receptor agonists and antagonists on the secretion of melatonin, luteinizing hormone and prolactin in the ram.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Luteinizing Hormone; Male; Melatonin; N-Methylaspartate; Photoperiod; Prolactin; Quinoxalines; Radioimmunoassay; Sheep | 1993 |
Responses mediated by excitatory and inhibitory amino acid receptors in solitary spiking cells from normal newt retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; N-Methylaspartate; Patch-Clamp Techniques; Receptors, Amino Acid; Retina; Salamandridae | 1995 |
Development of responses to excitatory and inhibitory amino acids in spiking cells during retinal regeneration in the adult newt.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Kainic Acid; N-Methylaspartate; Patch-Clamp Techniques; Receptors, Amino Acid; Regeneration; Retina; Salamandridae; Strychnine | 1995 |
DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclopropanes; Glycine; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotoxins; Pertussis Toxin; Receptors, Metabotropic Glutamate; Virulence Factors, Bordetella | 1996 |
Peripheral administration of NMDA, AMPA or KA results in pain behaviors in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Hindlimb; Kainic Acid; Logistic Models; Male; N-Methylaspartate; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1996 |
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium | 1996 |
Glutamate release evoked by glutamate receptor agonists in cultured chick retina cells: modulation by arachidonic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Benzofurans; Calcium Chloride; Cells, Cultured; Chick Embryo; Ethers, Cyclic; Excitatory Amino Acid Agonists; Fluorescent Dyes; Glutamic Acid; Indoles; Kainic Acid; Kinetics; N-Methylaspartate; Receptors, Glutamate; Retina; Sodium; Spectrometry, Fluorescence | 1996 |
Thyrotropin-releasing hormone facilitates spinal nociceptive responses by potentiating NMDA receptor-mediated transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Hot Temperature; Ketamine; Male; N-Methylaspartate; Pain Measurement; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Thyrotropin-Releasing Hormone | 1996 |
Ca(2+)-permeable AMPA/kainate and NMDA channels: high rate of Ca2+ influx underlies potent induction of injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Intracellular Membranes; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Osmolar Concentration; Permeability; Time Factors | 1996 |
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Magnetic Resonance Spectroscopy; Molecular Structure; N-Methylaspartate; Receptors, Metabotropic Glutamate | 1996 |
[Ca2+]i regulation by glutamate receptor agonists in cultured chick retina cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Chick Embryo; Excitatory Amino Acid Agonists; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Retina; Stimulation, Chemical | 1996 |
An early loss in membrane protein kinase C activity precedes the excitatory amino acid-induced death of primary cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Membrane; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; N-Methylaspartate; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1996 |
Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Weight; Circadian Rhythm; Eating; Excitatory Amino Acid Antagonists; Food Deprivation; Glutamic Acid; Hypothalamic Area, Lateral; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1996 |
Opposite effects of TGF-beta 1 on rapidly- and slowly-triggered excitotoxic injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Purkinje Cells; Rats; Time Factors; Transforming Growth Factor beta | 1996 |
The effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor agonists and antagonists on hypothalamic neurones in the anaesthetized rat which respond to changes in scrotal skin temperature.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hypothalamus; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Temperature | 1995 |
Interaction between striatal excitatory amino acid and gamma-aminobutyric acid (GABA) receptors in the turning behaviour of rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Caudate Nucleus; Data Interpretation, Statistical; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Kainic Acid; Male; N-Methylaspartate; Neostriatum; Picrotoxin; Putamen; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate | 1995 |
A patch clamp study of the effects of ciprofloxacin and biphenyl acetic acid on rat hippocampal neurone GABAA and ionotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Bicuculline; Cells, Cultured; Ciprofloxacin; Drug Interactions; Hippocampus; Kainic Acid; N-Methylaspartate; Patch-Clamp Techniques; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate | 1995 |
Release of vasopressin and oxytocin by excitatory amino acid agonists and the effect of antagonists on release by muscarine and hypertonic saline, in the rat in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diuresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Muscarine; Muscarinic Agonists; N-Methylaspartate; Oxytocin; Rats; Rats, Wistar; Saline Solution, Hypertonic; Urodynamics; Vasoconstrictor Agents; Vasopressins | 1996 |
Inhibition by NMDA of carbachol-stimulated inositol tetrakisphosphate accumulation in rat brain cortical slices.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; In Vitro Techniques; Inositol Phosphates; N-Methylaspartate; Ouabain; Phosphatidylinositols; Potassium; Rats; Sodium-Potassium-Exchanging ATPase; Veratridine | 1996 |
Potentiation of excitatory amino acid-evoked adenosine release from rat cortex by inhibitors of adenosine kinase and adenosine deaminase and by acadesine.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminoimidazole Carboxamide; Animals; Cerebral Cortex; Drug Synergism; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Ribonucleosides | 1996 |
Glutamate receptor regulation of rat nucleus accumbens neurons in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1996 |
N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor antagonists differentially suppress dorsal horn neuron responses to mechanical stimuli in rats with peripheral nerve injury.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Male; N-Methylaspartate; Neurons; Peripheral Nerve Injuries; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1996 |
Developmental changes in glutamate receptor-activated translocation of protein kinase C in cerebellar granule neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Carcinogens; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tritium | 1996 |
Glutathione-induced sodium currents in neocortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Free Radical Scavengers; Glutathione; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Sodium Channels | 1996 |
Postsynaptic modulation of NMDA synaptic currents in rat hippocampal microcultures by paired-pulse stimulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Agonists; GABA Agonists; Glutamic Acid; Hippocampus; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1996 |
Pharmacological characterization of metabotropic glutamate receptors potentiating NMDA responses in mouse cortical wedge preparations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; In Vitro Techniques; Male; Mice; N-Methylaspartate; Neurotoxins; Receptors, Metabotropic Glutamate | 1996 |
Metabotropic glutamate receptor activation contributes to nociceptive reflex activity in the rat spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reflex; Spinal Cord | 1996 |
The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cobalt; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Spinal Cord; Staining and Labeling; Time Factors | 1996 |
Microdialysis of a non-NMDA receptor antagonist into the L7 dorsal horn attenuates the pressor response to static muscle contraction but not passive stretch in cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cats; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart Rate; Lidocaine; Lumbosacral Region; Microdialysis; Muscle Contraction; Muscle Spindles; N-Methylaspartate; Reflex; Spinal Cord | 1996 |
Hemoglobin potentiates excitotoxic injury in cortical cell culture.
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antioxidants; Brain Injuries; Cells, Cultured; Cerebral Cortex; Chromans; Deferoxamine; Drug Synergism; Excitatory Amino Acids; Hemoglobin A; Humans; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons | 1996 |
Evidence that excitatory amino acids mediate afferent input to the primate somatosensory thalamus.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acids; Kainic Acid; Macaca; Male; Membrane Potentials; N-Methylaspartate; Thalamus | 1996 |
Thromboxane A2 agonist modulation of excitatory synaptic transmission in the rat hippocampal slice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Synaptic Transmission | 1996 |
N-methyl-D-aspartate acutely increases proenkephalin mRNA in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; Histocytochemistry; In Situ Hybridization; Injections, Intraventricular; Male; N-Methylaspartate; Prosencephalon; Protein Precursors; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 1995 |
Metabotropic glutamate receptors potentiate responses to NMDA and AMPA from layer V cells in rat visual cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; In Vitro Techniques; Iontophoresis; N-Methylaspartate; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 1996 |
N-Methyl-D-aspartate-induced enhancement of activator protein-1 DNA binding activity is blocked by ethanol in cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; DNA-Binding Proteins; Dose-Response Relationship, Drug; Ethanol; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1996 |
Maturation of a central glutamatergic synapse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Evoked Potentials; Glutamates; In Vitro Techniques; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Superior Colliculi; Synapses; Synaptic Transmission; Xenopus | 1996 |
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reinforcement, Psychology | 1996 |
Thyrotropin-releasing hormone (TRH) attenuates glutamate-stimulated increases in calcium in primary neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Electrophysiology; Glutamic Acid; Intracellular Membranes; Ion Channel Gating; N-Methylaspartate; Neurons; Rats; Thyrotropin-Releasing Hormone | 1996 |
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1996 |
In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Kainic Acid; Male; Maze Learning; N-Methylaspartate; Organ Specificity; Prosencephalon; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Regression Analysis; Tritium | 1996 |
Involvement of nitric oxide in spinally mediated capsaicin- and glutamate-induced behavioural responses in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, Tachykinin; Spinal Cord | 1996 |
alpha-Methyl derivatives of serine-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Motor Neurons; N-Methylaspartate; Rats; Receptors, Metabotropic Glutamate; Serine | 1996 |
In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Guanylate Cyclase; Hippocampus; Male; Microdialysis; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine | 1996 |
Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Isotopes; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Deferoxamine; Deuterium; Dizocilpine Maleate; Fetus; Gas Chromatography-Mass Spectrometry; Glucose; Hydrogen Peroxide; Iron; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Pentose Phosphate Pathway; Putamen; Quinoxalines; Rats | 1996 |
Corticofugal feedback can reduce the visual latency of responses to antagonistic stimuli.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Contrast Sensitivity; Efferent Pathways; Feedback; Geniculate Bodies; Humans; Models, Neurological; N-Methylaspartate; Neurons; Photic Stimulation; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retinaldehyde; Visual Cortex; Visual Pathways | 1996 |
Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine Agents; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Postpartum Period; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 1996 |
Glutamate as a putative neurotransmitter in the mollusc, Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Diphosphate; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Nervous System Physiological Phenomena; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Quisqualic Acid; Synapses; Thionucleotides | 1996 |
Excitatory amino acid regulation of astrocyte proteoglycans.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; CD57 Antigens; Cell Membrane; Cells, Cultured; Chondroitin Sulfates; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Heparitin Sulfate; Hippocampus; Immunohistochemistry; Kainic Acid; N-Methylaspartate; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Subcellular Fractions; Sulfates; Sulfur Radioisotopes | 1996 |
The ventral subiculum modulation of prepulse inhibition is not mediated via dopamine D2 or nucleus accumbens non-NMDA glutamate receptor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1996 |
mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; Kainic Acid; Male; N-Methylaspartate; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synapses; Synaptic Transmission | 1997 |
The effect of the desglycinyl metabolite of remacemide on cortical wedges prepared from DBA/2 mice.
Topics: Acetamides; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Anticonvulsants; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Female; Ion Channels; Male; Membrane Potentials; Mice; N-Methylaspartate; Phencyclidine; Phenethylamines; Receptors, N-Methyl-D-Aspartate; Reference Values | 1995 |
The influence of nitric oxide on perigeniculate GABAergic cell activity in the anaesthetized cat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Cycloleucine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Geniculate Bodies; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Penicillamine; Photic Stimulation; Quisqualic Acid; S-Nitroso-N-Acetylpenicillamine | 1996 |
NMDA and kainate-evoked release of nitric oxide and classical transmitters in the rat striatum: in vivo evidence that nitric oxide may play a neuroprotective role.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Potassium Chloride; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 1996 |
Differential effects of excitatory amino acids on mesencephalic neurons expressing either calretinin or tyrosine hydroxylase in primary cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calbindin 2; Cell Survival; Cells, Cultured; Excitatory Amino Acids; Kainic Acid; Mesencephalon; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Phenotype; Rats; S100 Calcium Binding Protein G; Tyrosine 3-Monooxygenase | 1996 |
Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Diclofenac; Ibuprofen; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substance P | 1996 |
Release of [3H]dopamine from striatal and cerebral cortical slices from rats with thioacetamide-induced hepatic encephalopathy: different responses to stimulation by potassium ions and agonists of ionotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Hepatic Encephalopathy; Kainic Acid; Male; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Thioacetamide; Tritium | 1997 |
Effects of excitatory amino acids and neuropeptide Y on the discharge activity of suprachiasmatic neurons in rat brain slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine Agents; Male; N-Methylaspartate; Neurons; Neuropeptide Y; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Strychnine; Suprachiasmatic Nucleus | 1997 |
An electrophysiological study of neurons in the horizontal limb of the diagonal band of Broca.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Frontal Lobe; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin | 1997 |
Glutamate and N-methyl-D-aspartate stimulate rat hypothalamic corticotropin-releasing factor secretion in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corticotropin-Releasing Hormone; Culture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hypothalamus; Kainic Acid; Male; N-Methylaspartate; Potassium Chloride; Rats; Rats, Wistar | 1997 |
The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid | 1997 |
Cholecystokinin and neurotensin inversely modulate excitatory synaptic transmission in the parabrachial nucleus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cholecystokinin; Devazepide; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hormone Antagonists; Interneurons; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Neurotensin; Patch-Clamp Techniques; Phenylurea Compounds; Pons; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin | 1997 |
Effects of glutamate receptor agonists and antagonists on Ca2+ uptake in rat hippocampal slices lesioned by glucose deprivation or by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1997 |
Experimental erbium laser surgery in the guinea pig cochlea: its use in the study of afferent cochlear neurotransmitters.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Erbium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Laser Therapy; Male; Microelectrodes; N-Methylaspartate; Neurotransmitter Agents; Synaptic Transmission | 1996 |
AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Glutamic Acid; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Thiazoles | 1997 |
Extrasynaptic glutamate spillover in the hippocampus: dependence on temperature and the role of active glutamate uptake.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport, Active; Diffusion; Electric Stimulation; Evoked Potentials; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Temperature | 1997 |
A novel NMDA receptor antagonist protects against N-methyl-D-aspartate- and glutamate-induced neurotoxicity in the goldfish retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Glutamic Acid; Goldfish; Hippocampus; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Diseases | 1997 |
Stereoselective effects-of 2,3-benzodiazepines in vivo: electrophysiology and neuroprotection studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Ischemic Attack, Transient; Isomerism; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord; Structure-Activity Relationship; Time Factors | 1996 |
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Distribution and projection of the medullary cardiovascular control neurons containing glutamate, glutamic acid decarboxylase, tyrosine hydroxylase and phenylethanolamine N-methyltransferase in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axonal Transport; Blood Pressure; Cardiovascular System; Electric Stimulation; Glutamate Decarboxylase; Glutamic Acid; Glycine; Heart Rate; Male; Medulla Oblongata; Microelectrodes; N-Methylaspartate; Neurons; Phenylethanolamine N-Methyltransferase; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 1997 |
Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrulline; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Synaptic repair mechanisms responsible for functional recovery in various cochlear pathologies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Cochlear Diseases; Dendrites; Excitatory Amino Acid Agonists; Guinea Pigs; Hair Cells, Auditory, Inner; Hearing; N-Methylaspartate; Nerve Regeneration; Receptors, N-Methyl-D-Aspartate; Synapses; Vestibulocochlear Nerve | 1997 |
Differential regulation of neuronal proteoglycans by activation of excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Cycloleucine; DNA Primers; Excitatory Amino Acid Agonists; Fetus; Glutamic Acid; Glycosylphosphatidylinositols; Glypicans; Heparan Sulfate Proteoglycans; Hippocampus; Lectins, C-Type; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurocan; Neurons; Neuroprotective Agents; Polymerase Chain Reaction; Proteoglycans; Rats; Receptors, Glutamate; RNA, Messenger; Transcription, Genetic | 1997 |
Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Animals, Newborn; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamates; Glycine; N-Methylaspartate; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Spinal Cord | 1996 |
Unilateral eyeball enucleation differentially alters AMPA-, NMDA- and kainate glutamate receptor binding in the newborn rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Autoradiography; Brain; Eye Enucleation; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Visual Cortex | 1996 |
Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: effect of homocysteine-induced seizures.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Reference Values; Seizures; Synaptic Membranes; Tritium | 1997 |
Regulation of cerebral microvessels by glutamatergic mechanisms.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microcirculation; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Vasoconstriction; Vasodilation | 1997 |
Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription Factor AP-1 | 1997 |
Glutamate receptor agonists evoked Ca(2+)-dependent and Ca(2+)-independent release of [3H]D-aspartate from cultured chick retina cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Cells, Cultured; Chickens; Excitatory Amino Acid Agonists; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Potassium Chloride; Receptors, Glutamate; Retina; Tritium | 1996 |
Discriminable excitotoxic effects of ibotenic acid, AMPA, NMDA and quinolinic acid in the rat laterodorsal tegmental nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics; Animals; Drug Evaluation, Preclinical; Ethanol; Excitatory Amino Acid Agonists; Ibotenic Acid; Locus Coeruleus; Male; N-Methylaspartate; Neurotoxins; Pentobarbital; Pons; Quinolinic Acid; Raphe Nuclei; Rats; Tegmentum Mesencephali | 1997 |
Dopamine regulates the glutamatergic inner hair cell activity in guinea pigs.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Dopamine; Dopamine Agonists; Dopamine Antagonists; Female; Glutamine; Guinea Pigs; Hair Cells, Auditory, Inner; N-Methylaspartate; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission | 1997 |
Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Apoptosis; Carbon; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Electron Spin Resonance Spectroscopy; Excitatory Amino Acid Agonists; Free Radical Scavengers; Fullerenes; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Patch-Clamp Techniques; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1996 |
NMDA receptor-mediated regulation of AMPA receptor properties in organotypic hippocampal slice cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calpain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Molecular Weight; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Tritium | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cysteine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; RNA, Messenger | 1997 |
N-methyl-D-aspartic acid-induced penile erection and yawning: role of hypothalamic paraventricular nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hemoglobins; Male; Methylene Blue; Microdialysis; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Yawning | 1997 |
Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Calcium; Cerebellum; Cycloleucine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Male; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Receptors, Glutamate | 1997 |
Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiazoles; Calcium; Cell Death; Coumarins; Dextrans; Excitatory Amino Acid Agonists; Fluorescent Dyes; Forecasting; Fura-2; Intracellular Membranes; Ions; Mice; N-Methylaspartate; Neurons; Neurotoxins; Osmolar Concentration; Thiazoles | 1997 |
The effects of metabolic stress on glutamate receptor-mediated depolarizations in the in vitro rat hippocampal slice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Hippocampus; Hypoxia; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Glutamate; Stress, Physiological; Synaptic Transmission | 1997 |
Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate.
Topics: Aconitate Hydratase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoates; Cerebellum; Citrates; Citric Acid Cycle; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Quinoxalines; Rats; Rats, Wistar; Substrate Specificity | 1997 |
Influences of excitatory amino acid receptor agonists on nucleus of the solitary tract neurons receiving aortic depressor nerve inputs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aorta; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Nervous System Physiological Phenomena; Neurons; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 1997 |
NMDA receptor coagonist glycine site: evidence for a role in lateral hypothalamic stimulation of feeding.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamic Area, Lateral; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1997 |
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Binding Sites; Corpus Striatum; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1997 |
Inhibition can disrupt hypersynchrony in model neuronal networks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; Models, Neurological; N-Methylaspartate; Neural Networks, Computer; Pyramidal Cells; Refractory Period, Electrophysiological; Synapses | 1997 |
Neuronal nitric oxide synthase and calmodulin-dependent protein kinase IIalpha undergo neurotoxin-induced proteolysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Fetus; Kainic Acid; Kinetics; Marine Toxins; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide Synthase; Okadaic Acid; Oxocins; Rats; Rats, Sprague-Dawley; Spectrin | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Dissociation of effects of glutamate receptor antagonists on excitotoxic and hypoxic neuronal cell death in a novel rat cortical culture system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cytological Techniques; Glutamic Acid; Hypoxia; N-Methylaspartate; Neurons; Neurotoxins; Rats; Receptors, Glutamate | 1997 |
Potentiation of NMDA and AMPA responses by group I mGluR in spinal cord motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord | 1997 |
Bioisosterically modified dipeptide excitatory amino acid receptor antagonists containing 3-oxygenated isothiazole ring systems.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; Corpus Callosum; Dipeptides; Electrophysiology; Excitatory Amino Acid Antagonists; Kainic Acid; Models, Chemical; N-Methylaspartate; Piperazines; Rats; Receptors, AMPA; Stereoisomerism | 1997 |
Role of spinal NMDA and AMPA receptors in episodic hypertension in conscious spinal rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Consciousness; Excitatory Amino Acid Antagonists; Heart Rate; Hypertension; Male; N-Methylaspartate; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord | 1997 |
NMDA-Independent LTP by adenosine A2 receptor-mediated postsynaptic AMPA potentiation in hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Hippocampus; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission | 1997 |
AMPA receptor-mediated regulation of a Gi-protein in cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; GTP-Binding Proteins; N-Methylaspartate; Neurons; Rats; Receptors, AMPA; Signal Transduction; Sodium | 1997 |
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1997 |
Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Ferrets; gamma-Aminobutyric Acid; Indoles; Ligands; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tropisetron; Virulence Factors, Bordetella; Visual Cortex | 1997 |
Regulation of gonadotropin-releasing hormone and luteinizing hormone secretion by AMPA receptors. Evidence for a physiological role of AMPA receptors in the steroid-induced luteinizing hormone surge.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Luteinizing Hormone; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Ovariectomy; Preoptic Area; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Effect of excitatory amino acids on rat hypothalamic somatostatin secretion in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Hypothalamus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Potassium Chloride; Rats; Rats, Wistar; Receptors, Glutamate; Somatostatin | 1997 |
The effect of thiopental and propofol on NMDA- and AMPA-mediated glutamate excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Intravenous; Animals; Dimethyl Sulfoxide; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Propofol; Rats; Rats, Sprague-Dawley; Thiopental | 1997 |
Interaction of GABA and excitatory amino acids in the basolateral amygdala: role in cardiovascular regulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Arousal; Bicuculline; Blood Pressure; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Picrotoxin; Piperazines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Kainate excitotoxicity is mediated by AMPA- but not kainate-preferring receptors in embryonic rat hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 1997 |
Melatonin blocks the induction of long-term potentiation in an N-methyl-D-aspartate independent manner.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Culture Media; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; Magnesium; Melatonin; N-Methylaspartate; Perfusion; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1997 |
Actions of compounds manipulating the nitric oxide system in the cat primary visual cortex.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cats; Cyclic GMP; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acids; Hydrazines; Iontophoresis; N-Methylaspartate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrogen Oxides; Visual Cortex | 1997 |
Spinal calmodulin inhibitors reduce N-methyl-D-aspartate- and septide-induced nociceptive behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Enzyme Inhibitors; Imidazoles; Injections, Intraventricular; Male; N-Methylaspartate; Neurokinin A; Pain; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Spinal Cord; Substance P; Sulfonamides | 1997 |
Characterization of the anoxia-induced long-term synaptic potentiation in area CA1 of the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chelating Agents; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Synapses | 1997 |
The non-competitive AMPA antagonist LY 300168 (GYKI 53655) attenuates AMPA-induced hippocampal injury in neonatal rodents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Atrophy; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Injections, Intraperitoneal; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1997 |
Measurement of intracellular free zinc in living cortical neurons: routes of entry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Ionophores; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neocortex; Neurons; Nimodipine; Quinoxalines; Sodium-Calcium Exchanger; Zinc | 1997 |
Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Behavior, Animal; Excitatory Amino Acid Antagonists; Indoles; Male; Mice; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1997 |
The effect of losigamone (AO-33) on electrical activity and excitatory amino acid release in mouse cortical slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Furans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; N-Methylaspartate | 1997 |
Models of neuronal transient synchrony during propagation of activity through neocortical circuitry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; Mathematics; Models, Neurological; N-Methylaspartate; Neocortex; Neurons; Synapses; Synaptic Transmission | 1998 |
Impairment of brain kynurenic acid production by glutamate metabotropic receptor agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cycloleucine; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sodium | 1997 |
Spinal cord excitatory amino acid receptors and plasma catecholamine autonomic responses in the conscious rabbit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arteries; Autonomic Nervous System; Baroreflex; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Consciousness; Drug Administration Routes; Excitatory Amino Acid Agonists; Female; Male; N-Methylaspartate; Nitroprusside; Rabbits; Receptors, Glutamate; Spinal Cord; Vasodilator Agents | 1997 |
Breathing of awake goats during prolonged dysfunction of caudal M ventrolateral medullary neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Cold Temperature; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Goats; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Neurons; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics | 1998 |
Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kinetics; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Rats; Spinal Cord | 1997 |
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; Rats; Time Factors | 1998 |
Taurine release from the developing and ageing hippocampus: stimulation by agonists of ionotropic glutamate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Female; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Glutamate; Taurine | 1997 |
Synapse-specific accumulation of lithium in intracellular microdomains: a model for uncoupling coincidence detection in the brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Computer Simulation; Electric Conductivity; Electrophysiology; Extracellular Space; Female; Intracellular Membranes; Kainic Acid; Lithium; Models, Neurological; N-Methylaspartate; Neural Conduction; Neurons; Oocytes; Permeability; Substrate Specificity; Synapses; Xenopus | 1998 |
Ethanol modulates N-methyl-D-aspartate-evoked arachidonic acid release from neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Glutamic Acid; Mice; N-Methylaspartate; Neurons | 1997 |
Activation of non-NMDA receptors stimulates acetylcholine and GABA release from dorsal hippocampus: a microdialysis study in the rat.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microdialysis; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1998 |
Evidence that functional glutamate receptors are not expressed on rat or human cerebromicrovascular endothelial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Calcium; Capillaries; Cattle; Cells, Cultured; Cerebrovascular Circulation; Colforsin; Cyclic AMP; Cycloleucine; Endothelin-1; Endothelium, Vascular; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Kainic Acid; Mice; N-Methylaspartate; Neurons; Polymerase Chain Reaction; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Second Messenger Systems | 1998 |
Networks of coactive neurons in developing layer 1.
Topics: Acetylcholine; Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Muscimol; N-Methylaspartate; Neurons; Neurotransmitter Agents; Norepinephrine; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin; Time Factors | 1998 |
Enhanced visual responses in cat dLGN--potentiation by priming with excitatory amino acids.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Cycloleucine; Drug Synergism; Excitatory Amino Acids; Geniculate Bodies; Iontophoresis; N-Methylaspartate; Neurons; Neuroprotective Agents; Photic Stimulation; Visual Perception | 1998 |
The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Electric Conductivity; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; N-Methylaspartate; Neurons; NF-kappa B; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1998 |
Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: implications for ischemia and Huntington's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Huntington Disease; Interneurons; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Drug Synergism; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Macaca fascicularis; Male; N-Methylaspartate; Thalamic Nuclei | 1998 |
Effect of glutamate receptor agonists on catecholamine secretion in bovine chromaffin cells.
Topics: Adrenal Medulla; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nicotine; Receptors, Glutamate | 1998 |
Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; N-Methylaspartate; Naphthols; Neurons, Afferent; Neuroprotective Agents; Propylene Glycols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus | 1998 |
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium | 1998 |
Metabotropic glutamate receptor activation modulates sound level processing in the cochlear nucleus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Auditory Perception; Benzoates; Cats; Cochlear Nucleus; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; N-Methylaspartate; Neurons; Neuroprotective Agents; Receptors, Metabotropic Glutamate; Time Factors | 1998 |
Glutamate-stimulated neuropeptide Y mRNA expression in the rat dentate gyrus: a prominent role of metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Injections; Injections, Intraperitoneal; Male; N-Methylaspartate; Neuropeptide Y; Neuropeptides; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger | 1998 |
Characterization of temperature rise of the brain and the rectum following intracerebroventricular administration of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Body Temperature; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indomethacin; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rectum | 1998 |
Area postrema glutamate receptors mediate respiratory and gastric responses in the rabbit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Ventricles; Electric Stimulation; Excitatory Amino Acid Antagonists; Homocysteine; Male; Microinjections; Myocardial Contraction; N-Methylaspartate; Neurons, Efferent; Rabbits; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Stereoisomerism; Stomach | 1998 |
Changes in GluR4 expression induced by metabotropic receptor activation in radial glia cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Cycloleucine; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Polymerase Chain Reaction; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Retina; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1998 |
Variability of AMPA and NMDA receptor mediated responses in CA1 pyramidal cells of young rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive component of glutamate neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cycloleucine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Fluorescent Dyes; Glutamic Acid; Humans; Hypothermia, Induced; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins; Synapses | 1998 |
Selective modulation of GABAA receptors by aluminum.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aluminum; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons, Afferent; Olfactory Bulb; Patch-Clamp Techniques; Rats; Receptors, GABA-A; Receptors, Glutamate; Smell | 1998 |
Reevaluation of ACEA 1021 as an antagonist at the strychnine-insensitive glycine site of the N-methyl-D-aspartate receptor.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neocortex; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate | 1998 |
Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Hippocampus; N-Methylaspartate; Nerve Growth Factors; Neurotrophin 3; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Infusional high-dose application of the calcium-channel-blocking and antiglutamatergic agent caroverine in the treatment of alcohol withdrawal (DSM-III-R 291.80).
Topics: Adult; Alcohols; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Female; Humans; Infusion Pumps; Infusions, Intravenous; Male; Middle Aged; N-Methylaspartate; Pilot Projects; Quinoxalines; Substance Withdrawal Syndrome | 1998 |
Nerve growth factor rapidly suppresses basal, NMDA-evoked, and AMPA-evoked nitric oxide synthase activity in rat hippocampus in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Hippocampus; Microdialysis; N-Methylaspartate; Nerve Growth Factors; Nitric Oxide Synthase; Rats; Receptors, Glutamate; Recombinant Proteins | 1998 |
Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Bumetanide; Carrier Proteins; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agents; Gene Expression Regulation; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Neuroblastoma; Neurons; Potassium; Receptors, Glutamate; Sodium-Potassium-Chloride Symporters; Tumor Cells, Cultured | 1998 |
Effects of intrathecal NMDA and non-NMDA antagonists on acute thermal nociception and their interaction with morphine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Hot Temperature; Morphine; N-Methylaspartate; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1998 |
Experience-dependent changes in the importance of N-methyl-D-aspartate (NMDA) receptors for visual transmission in superior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Darkness; Gene Expression Regulation, Developmental; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Superior Colliculi; Visual Perception | 1998 |
Serotonergic modulation of the responses to excitatory amino acids of rat dorsal horn neurons in vitro: implications for somatosensory transmission.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; N-Methylaspartate; Neurons; Rats; Sensation; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission | 1998 |
Endogenous ACh enhances striatal NMDA-responses via M1-like muscarinic receptors and PKC activation.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Corpus Striatum; Egtazic Acid; Electric Stimulation; Enzyme Activation; Excitatory Amino Acids; In Vitro Techniques; Male; Microelectrodes; Microinjections; Muscarine; N-Methylaspartate; Neostigmine; Neurons; Protein Kinase C; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Synaptic Transmission | 1998 |
NMDA and non-NMDA ionotropic glutamate receptors modulate striatal acetylcholine release via pre- and postsynaptic mechanisms.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corpus Striatum; In Vitro Techniques; Male; N-Methylaspartate; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptosomes; Tetrodotoxin | 1998 |
Regulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Trigeminal Nuclei | 1998 |
Glutamatergic and GABAergic agonists increase [Ca2+]i in avian cochlear nucleus neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; GABA Agonists; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Stimulation, Chemical | 1998 |
Frequency potentiation in the medial cortex of young turtle brains in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Septum Pellucidum; Turtles | 1998 |
The effect of ACPD on the responses to NMDA and AMPA varies with layer in slices of rat visual cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Drug Synergism; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Visual Cortex | 1998 |
NMDA and AMPA receptors evoke transmitter release from noradrenergic axon terminals in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1998 |
Supraoptic oxytocin and vasopressin neurones show differential sensitivity to the neurosteroid pregnenolone sulphate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; N-Methylaspartate; Neurons; Oxytocin; Pregnenolone; Rats; Rats, Wistar; Supraoptic Nucleus; Vasopressins | 1998 |
GABA(A) receptor modulates the activity of inner hair cell afferents in guinea pig cochlea.
Topics: Acetylcholine; Action Potentials; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Baclofen; Bicuculline; Cochlea; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Muscimol; N-Methylaspartate; Receptors, GABA-A | 1998 |
Conformational changes of the smooth endoplasmic reticulum are facilitated by L-glutamate and its receptors in rat Purkinje cells.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apnea; Bradycardia; Calcium Signaling; Cycloleucine; Dendrites; Endoplasmic Reticulum, Smooth; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia, Brain; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Respiration | 1998 |
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Brain Stem; Dizocilpine Maleate; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Inferior Colliculi; N-Methylaspartate; Neuroprotective Agents; Propylthiouracil; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Taurine, glutamate and GABA modulate the outgrowth from goldfish retinal explants and its concentrations are affected by the crush of the optic nerve.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Culture Techniques; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Goldfish; N-Methylaspartate; Neurites; Optic Nerve; Retina; Taurine | 1998 |
COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Indomethacin; Injections, Spinal; Isoenzymes; Male; N-Methylaspartate; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Injection of MK-801 affects ocular dominance shifts more than visual activity.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye; Functional Laterality; N-Methylaspartate; Neuronal Plasticity; Sensory Deprivation; Vision, Monocular; Vision, Ocular; Visual Cortex | 1999 |
Activation of NMDA and non-NMDA receptors in the caudal ventrolateral medulla dilates the airways.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine Derivatives; Autonomic Nervous System; Bronchoconstriction; Cholinergic Fibers; Dogs; Electric Stimulation; Excitatory Amino Acid Agonists; Female; Kainic Acid; Lung; Male; Medulla Oblongata; Muscle, Smooth; N-Methylaspartate; Parasympatholytics; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 1998 |
Glutamatergic induction of CREB phosphorylation and Fos expression in primary cultures of the suprachiasmatic hypothalamus in vitro is mediated by co-ordinate activity of NMDA and non-NMDA receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cricetinae; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Gene Expression; Genes, fos; Glutamic Acid; Kainic Acid; Male; Mesocricetus; N-Methylaspartate; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 1999 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Culture Techniques; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Disease Models, Animal; Electroshock; Hydrobromic Acid; Hydrochloric Acid; Hydroxy Acids; Inhibitory Concentration 50; Mice; N-Methylaspartate; Organophosphonates; Quinoxalines | 1999 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Excitatory amino acid responses in relay neurons of the rat lateral geniculate nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Concanavalin A; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Geniculate Bodies; Glutamic Acid; Glycine; Ionophores; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Nystatin; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Multiple types of spontaneous excitatory synaptic currents in salamander retinal ganglion cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Animals; Convulsants; Darkness; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Larva; N-Methylaspartate; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Strychnine; Synapses; Synaptic Vesicles | 1999 |
Activation of excitatory amino acid receptors in bovine dental pulp evokes the release of iCGRP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Cattle; Dental Pulp; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurogenic Inflammation; Neurons, Afferent; Nociceptors; Radioimmunoassay; Receptors, Glutamate; Statistics, Nonparametric | 1999 |
Analyses of taste nerve responses with special reference to possible receptor mechanisms of umami taste in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chorda Tympani Nerve; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Inosine Monophosphate; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Potassium; Propionates; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Taste | 1999 |
Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; N-Methylaspartate; Pyramidal Cells; Rats | 1999 |
Ionotropic glutamate receptors in isolated horizontal cells of the rabbit retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1999 |
Spatiotemporal patterning of glutamate receptors in developing ferret striate cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ferrets; Kainic Acid; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium; Visual Cortex | 1999 |
Visual experience alters the molecular profile of NMDA-receptor-mediated sensory transmission.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dark Adaptation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons, Afferent; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synaptic Transmission; Visual Pathways | 1999 |
Excitatory amino acids and synaptic transmission in embryonic rat brainstem motoneurons in organotypic culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Coculture Techniques; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Recurrent mossy fiber pathway in rat dentate gyrus: synaptic currents evoked in presence and absence of seizure-induced growth.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Dentate Gyrus; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Feedback; GABA Antagonists; Kainic Acid; Male; Mossy Fibers, Hippocampal; N-Methylaspartate; Organ Culture Techniques; Parasympathomimetics; Patch-Clamp Techniques; Perforant Pathway; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Status Epilepticus; Synapses | 1999 |
Mapping glutamatergic drive in the vertebrate retina with a channel-permeant organic cation.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Artifacts; Biological Transport; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Kainic Acid; Male; Models, Biological; Models, Molecular; N-Methylaspartate; Neurons; Rabbits; Retina; Retinal Ganglion Cells | 1999 |
Beta-alanine release from the adult and developing hippocampus is enhanced by ionotropic glutamate receptor agonists and cell-damaging conditions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; beta-Alanine; Cell Hypoxia; Drug Synergism; Excitatory Amino Acid Agonists; Female; Free Radicals; Glucose; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Nitrogen; Oxidative Stress; Sodium | 1999 |
Clozapine, but not haloperidol, prevents the functional hyperactivity of N-methyl-D-aspartate receptors in rat cortical neurons induced by subchronic administration of phencyclidine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Clozapine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Haloperidol; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Potentiation and depression following stimulus interruption in young rat hippocampi.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Nifedipine; Rats; Rats, Sprague-Dawley; Reference Values | 1999 |
Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Effects of corticosterone on excitatory amino acid responses in dopamine-sensitive neurons in the ventral tegmental area.
Topics: Action Potentials; Aldosterone; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corticosterone; Dopamine; Drug Synergism; Electrophysiology; Excitatory Amino Acids; In Vitro Techniques; Kainic Acid; Male; Mifepristone; N-Methylaspartate; Neurons; Rats; Receptors, Glucocorticoid; Tegmentum Mesencephali; Time Factors | 1999 |
Actions of 8-bromo-cyclic-GMP on neurones in the rat thalamus in vivo and in vitro.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Geniculate Bodies; Guanylate Cyclase; In Vitro Techniques; Molsidomine; N-Methylaspartate; Neurons, Afferent; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar | 1999 |
Ethanol inhibition of synaptically evoked kainate responses in rat hippocampal CA3 pyramidal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ethanol; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Synapses | 1999 |
Differential roles of ionotropic glutamate receptors in canine medullary inspiratory neurons of the ventral respiratory group.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dogs; Excitatory Amino Acid Antagonists; Female; Inhalation; Male; Medulla Oblongata; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Modulation of the mesolimbic dopamine system by glutamate: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Binding, Competitive; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Limbic System; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 1999 |
Modulation of cardiovascular effects produced by nitric oxide and ionotropic glutamate receptor interaction in the nucleus tractus solitarii of rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cardiovascular Physiological Phenomena; Excitatory Amino Acid Agonists; Indazoles; Male; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Solitary Nucleus | 1999 |
Presynaptic inhibition preferentially reduces in NMDA receptor-mediated component of transmission in rat midbrain dopamine neurons.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Cesium; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Agonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Mesencephalon; N-Methylaspartate; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
N-methyl-D-aspartate receptor agonists modulate homocysteine-induced developmental abnormalities.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Cycloserine; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Homocysteine; N-Methylaspartate; Nervous System; Nervous System Malformations; Receptors, N-Methyl-D-Aspartate; Teratogens | 1999 |
Orphanin FQ (nociceptin) modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli, and blocks the substance P-induced facilitation of N-methyl-D-aspartate-evoked responses.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Injections, Intraventricular; Iontophoresis; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neurons; Nociceptin; Opioid Peptides; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatosensory Cortex; Substance P; Trigeminal Nerve | 1999 |
Role of intracellular Ca(2+) stores shaping normal activity in brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Dantrolene; Hippocampus; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Radioligand Assay; Rats; Rats, Wistar; Reference Values; Spectrometry, Fluorescence | 1999 |
Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Signaling; Cyclooxygenase Inhibitors; Eicosanoids; Excitatory Amino Acid Agonists; Glutamic Acid; Indomethacin; Iontophoresis; Male; N-Methylaspartate; Neurons, Afferent; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Substance P | 1999 |
Inhibition of excitatory neurotransmitter-nitric oxide signaling pathway by inhalational anesthetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Arginine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Halothane; Isoflurane; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction | 1999 |
Functional activation of punch-cultured magnocellular neuroendocrine cells by glutamate receptor subtypes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine Vasopressin; Calcium; Cell Culture Techniques; Cells, Cultured; Cycloleucine; Excitatory Amino Acid Agonists; Fetus; Kainic Acid; N-Methylaspartate; Neurons; Neurophysins; Neurosecretory Systems; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus | 1999 |
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetus; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Passive avoidance training results in increased responsiveness of voltage- and ligand-gated calcium channels in chick brain synaptoneurosomes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Brain Chemistry; Calcium; Calcium Channels; Chickens; Electric Stimulation; Excitatory Amino Acid Agonists; Feeding Behavior; Female; Ligands; Male; Membrane Potentials; Membrane Proteins; Memory; N-Methylaspartate; ortho-Aminobenzoates; Potassium Chloride; Receptors, Glutamate; Subcellular Fractions; Synaptosomes | 1999 |
Metabotropic glutamate receptors group I are involved in cochlear neurotransmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Indans; Methoxyhydroxyphenylglycol; N-Methylaspartate; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Inhibition of caspase activity in retinal cell apoptosis induced by various stimuli in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies, Monoclonal; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Hypoxia; Cell Line; Enzyme Inhibitors; Heat-Shock Proteins; In Situ Nick-End Labeling; N-Methylaspartate; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Retina | 1999 |
Role of glutamate receptors in transmission of vagal cardiac input to neurones in the nucleus tractus solitarii in dogs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dogs; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart; In Vitro Techniques; Microelectrodes; N-Methylaspartate; Neurons; Neurons, Afferent; Quinoxalines; Receptors, Glutamate; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 1999 |
Evaluation of agonists and antagonists acting at Group I metabotropic glutamate receptors in the thalamus in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Phospholipid Ethers; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Thalamus | 1999 |
Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzophenanthridines; Calcium; Cycloleucine; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; N-Methylaspartate; Phenanthridines; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Spinal Cord | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Neural mechanisms potentially contributing to the intersegmental phase lag in lamprey.II. Hemisegmental oscillations produced by mutually coupled excitatory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Computer Simulation; Lampreys; Locomotion; Models, Biological; N-Methylaspartate; Nerve Net; Neurons; Spinal Cord | 1999 |
Regulation of substantia nigra pars reticulata neuronal activity by excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substantia Nigra | 1999 |
Premotor input to hypoglossal motoneurons from Kölliker-Fuse neurons in decerebrate cats.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Electric Stimulation; Electrophysiology; Excitatory Amino Acids; Histocytochemistry; Hypoglossal Nerve; Kainic Acid; Laryngeal Nerves; Microinjections; Motor Neurons; N-Methylaspartate; Phrenic Nerve; Receptors, Glutamate | 1999 |
Stimulation of NMDA and AMPA receptors in the rat nucleus basalis of Meynert affects sleep.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Nucleus of Meynert; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinoxalines; Rats; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sleep; Sleep Stages; Wakefulness | 1999 |
Functional changes of N-methyl-D-aspartic acid and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate channels in gerbil hippocampal CA1, in relation to postischemic enhancement of glutamate receptor-mediated responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Gerbillinae; Hippocampus; Ion Channels; Ischemic Attack, Transient; Male; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
Developmental changes in NMDA-induced intrinsic optical signals in the hippocampal dentate gyrus of children with medically intractable seizures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Survival; Child; Child Development; Child, Preschool; Dentate Gyrus; Extracellular Space; Humans; In Vitro Techniques; Infant; Light; Magnesium; N-Methylaspartate; Optics and Photonics; Rats; Seizures | 1999 |
The ontogeny of glutamate receptors and D-aspartate binding sites in the ovine CNS.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Embryonic and Fetal Development; Fetus; Glutamic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Sheep | 1999 |
Locomotor activity and accumbens Fos expression driven by ventral hippocampal stimulation require D1 and D2 receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Benzazepines; Brain Chemistry; Cycloleucine; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Excitatory Amino Acid Agonists; Genes, Immediate-Early; Glutamic Acid; Haloperidol; Hippocampus; Kainic Acid; Lidocaine; Locomotion; Male; N-Methylaspartate; Neural Pathways; Neuroprotective Agents; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1999 |
Glutamate and GABA activate different receptors and Cl(-) conductances in crab peptide-secretory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brachyura; Cells, Cultured; Chloride Channels; Chlorides; Concanavalin A; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quisqualic Acid; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate | 2000 |
Cholecystokinin (CCK) increases GABA release in the rat anterior nucleus accumbens via CCK(B) receptors located on glutamatergic interneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholecystokinin; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stimulation, Chemical; Tetrodotoxin | 2000 |
Intracellular survival pathways against glutamate receptor agonist excitotoxicity in cultured neurons. Intracellular calcium responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Exocytosis; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Potassium; Rats; Receptors, Glutamate | 1999 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Attenuation of neuronal death by NMDA and oxygen-glucose deprivation in cortical neurons maintained in high glucose.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Fetus; Glucose; Kainic Acid; Mice; Mice, Inbred ICR; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins | 1999 |
Kainate receptors activate NF-kappaB via MAP kinase in striatal neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcimycin; Calcium; Cells, Cultured; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; Immunohistochemistry; In Vitro Techniques; Ionophores; Kainic Acid; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; NF-kappa B; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Transcription Factor RelA | 2000 |
The gain of the baroreflex bradycardia is reduced by microinjection of NMDA receptor antagonists into the nucleus tractus solitarii of awake rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Bradycardia; Cardiovascular System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus | 2000 |
Effects of dalargin on excitation induced by L-glutamate agonists in the frog vestibular organs.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dendrites; Electrophysiology; Enkephalin, Leucine-2-Alanine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons, Afferent; Rana temporaria; Receptors, Opioid; Synapses; Vestibule, Labyrinth | 2000 |
Control of synaptic depression by glutamate transporters.
Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission | 2000 |
Differential vulnerability of hippocampus, basal ganglia, and prefrontal cortex to long-term NMDA excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Basal Ganglia; Calcinosis; Excitatory Amino Acid Agonists; Globus Pallidus; Hippocampus; Humans; Male; Microinjections; Monoamine Oxidase; N-Methylaspartate; Neurons; Organ Specificity; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
Neuroprotective effects of creatine administration against NMDA and malonate toxicity.
Topics: Administration, Oral; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corpus Striatum; Creatine; Energy Metabolism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Malonates; Mitochondria; N-Methylaspartate; Neuroprotective Agents; Niacinamide; Rats; Rats, Sprague-Dawley | 2000 |
Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Isoxazoles; N-Methylaspartate; Propionates; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2000 |
Ionotropic glutamate receptor-mediated responses in the rat primary somatosensory cortex evoked by noxious and innocuous cutaneous stimulation in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Hot Temperature; Male; N-Methylaspartate; Neurons; Pain; Piperazines; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Skin; Somatosensory Cortex; Synapses; Time Factors | 2000 |
Neurotrophin 3 potentiates glutamatergic responses of IHC afferents in the cochlea in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Carbazoles; Cochlea; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hair Cells, Auditory, Inner; In Vitro Techniques; Indole Alkaloids; Male; N-Methylaspartate; Nerve Fibers; Neurotrophin 3; Receptor, trkB; Receptor, trkC; Synapses | 2000 |
Involvement of NMDA-receptor in kainate-induced neurotoxicity in cultured fetal retinal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Retina | 2000 |
Effect of intracerebral administration of NMDA and AMPA on dopamine and glutamate release in the ventral pallidum and on motor behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Brain; Dopamine; Excitatory Amino Acid Agonists; Globus Pallidus; Glutamic Acid; Injections; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 2000 |
Inhibition by adenosine A(2A) receptors of NMDA but not AMPA currents in rat neostriatal neurons.
Topics: Adenylyl Cyclases; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; N-Methylaspartate; Neurons; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Type C Phospholipases; Visual Cortex | 2000 |
Blocking the trigeminal EPSP in rat abducens motoneurons in vivo with the AMPA antagonists NBQX and GYKI 53655.
Topics: Abducens Nerve; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Male; Motor Neurons; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Trigeminal Nerve | 2000 |
Somatostatin potentiates NMDA receptor function via activation of InsP(3) receptors and PKC leading to removal of the Mg(2+) block without depolarization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Electrophysiology; Enzyme Activation; Enzyme Activators; GTP-Binding Proteins; Hormone Antagonists; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Magnesium; Male; N-Methylaspartate; Nerve Endings; Peptides; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Somatostatin; Sympathetic Nervous System; Synaptosomes | 2000 |
Biophysical properties and responses to glutamate receptor agonists of identified subpopulations of rat geniculate ganglion neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Size; Cells, Cultured; Excitatory Amino Acid Agonists; Female; Geniculate Ganglion; Glutamic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission; Taste | 2000 |
Differential modulatory roles of cholera toxin and pertussis toxin in the regulation of pain responses induced by excitatory amino acids administered intrathecally in mice.
Topics: Adjuvants, Immunologic; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholera Toxin; Excitatory Amino Acid Agonists; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Pain; Pertussis Toxin; Spinal Cord; Virulence Factors, Bordetella | 2000 |
Interactions of glutamate receptor agonists with long-term potentiation in the rat hippocampal slice.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2000 |
NMDA-induced changes in a cortical network in vivo are prevented by AMPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Nerve Net; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Effects of glutamate agonist versus procaine microinjections into the basal forebrain cholinergic cell area upon gamma and theta EEG activity and sleep-wake state.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Arousal; Behavior, Animal; Cholinergic Fibers; Electromyography; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microinjections; N-Methylaspartate; Neurons; Procaine; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sleep; Theta Rhythm | 2000 |
Characterization of audiogenic-like seizures in naive rats evoked by activation of AMPA and NMDA receptors in the inferior colliculus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Suckling; Benzothiadiazines; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Hypothyroidism; Inferior Colliculi; Injections, Intraventricular; Male; Maternal Exposure; N-Methylaspartate; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 2000 |
Guanine nucleotides block agonist-driven 45Ca2+ influx in chick embryo retinal explants.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Chick Embryo; Excitatory Amino Acid Antagonists; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Monophosphate; N-Methylaspartate; Organ Culture Techniques; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina; Thionucleotides | 2000 |
Differential effects of calcitonin gene-related peptide and calcitonin gene-related peptide 8-37 upon responses to N-methyl-D-aspartate or (R, S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate in spinal nociceptive neurons with knee joint input in t
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Excitatory Amino Acid Agonists; Knee Joint; Male; N-Methylaspartate; Nociceptors; Peptide Fragments; Posterior Horn Cells; Rats; Rats, Wistar | 2000 |
Glutamate-induced production of nitric oxide in guinea pig vestibular sensory cells.
Topics: Acoustic Maculae; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fluorescein; Fluorescent Dyes; Glutamic Acid; Guinea Pigs; Hair Cells, Vestibular; Microscopy, Fluorescence; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 2000 |
Functional ionotropic glutamate receptors emerge during terminal cell division and early neuronal differentiation of rat neuroepithelial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bromodeoxyuridine; Calcium; Cell Differentiation; Cells, Cultured; DNA Primers; Epithelial Cells; Epitopes; Excitatory Amino Acid Agonists; Female; Flow Cytometry; Gene Expression Regulation, Developmental; Kainic Acid; Membrane Potentials; Mitosis; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stem Cells; Telencephalon; Transcription, Genetic | 2000 |
Bradycardic responses to microinjection of N-methyl-D-aspartate into the nucleus tractus solitarius are inhibited by local activation of 5-HT(3) receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Bicuculline; Biguanides; Excitatory Amino Acid Agonists; GABA Antagonists; Granisetron; Heart Rate; Hemodynamics; Male; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System | 2000 |
Subchronic treatment with either clozapine, olanzapine or haloperidol produces a hyposensitive response of the rat cortical cells to N-methyl-D-aspartate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Haloperidol; In Vitro Techniques; Male; N-Methylaspartate; Olanzapine; Pharmaceutical Vehicles; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Bilirubin does not modulate ionotropic glutamate receptors or glutamate transporters.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Bilirubin; Glutamic Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Corticotropin-Releasing Hormone; Excitatory Amino Acid Agonists; Hypothalamus; L-Lactate Dehydrogenase; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley | 2000 |
In situ Ca2+ imaging reveals neurotransmitter receptors for glutamate in taste receptor cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Dextrans; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Microscopy, Confocal; N-Methylaspartate; Neurotransmitter Agents; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Taste Buds | 2000 |
NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Cell Death; Cells, Cultured; Corpus Striatum; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Microinjections; N-Methylaspartate; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Sindbis Virus; Transfection | 2000 |
Influence of an extracellular acidosis on excitatory synaptic transmission and long-term potentiation in the CA1 region of rat hippocampal slices.
Topics: Acidosis; Action Potentials; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Cell Membrane; Cerebrospinal Fluid; Electric Stimulation; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Sodium Bicarbonate; Sodium-Hydrogen Exchangers; Sulfuric Acids; Synaptic Transmission | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Ionotropic glutamate receptors expressed in human retinoblastoma Y79 cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Blotting, Northern; Calcium; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gene Expression; Humans; Intracellular Fluid; Kainic Acid; N-Methylaspartate; Photoreceptor Cells, Vertebrate; Receptors, Glutamate; Retinoblastoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2000 |
A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Biological Transport; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Kinetics; Mice; Models, Theoretical; N-Methylaspartate; Sodium; Symporters | 2000 |
Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcineurin; Calcium Signaling; Cell Compartmentation; Cells, Cultured; Dendrites; Endocytosis; Excitatory Postsynaptic Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
The N-methyl-D-aspartate antagonistic and opioid components of d-methadone antinociception in the rat spinal cord.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesia; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methadone; N-Methylaspartate; Naloxone; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2000 |
Glutamate-gated calcium fluxes in Arabidopsis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arabidopsis; Calcium; Egtazic Acid; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Ion Channels; Lanthanum; N-Methylaspartate | 2000 |
Activation of ionotropic glutamate receptors reduces the production of transforming growth factor-beta2 by developing neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta | 2000 |
Mechanism of inhibition by ethanol of NMDA and AMPA receptor channel functions in cultured rat cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; Drug Interactions; Electric Stimulation; Ethanol; Excitatory Amino Acid Agonists; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Gene Expression Regulation; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcription, Genetic | 2001 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
Dendritic glutamate-induced bursting in prefrontal pyramidal cells: role of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Glutamic Acid; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Role of non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophysial explants.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Glutamates; Hypothalamo-Hypophyseal System; Kainic Acid; Kinetics; Male; N-Methylaspartate; Organ Culture Techniques; Oxytocin; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 2001 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Balance between four types of synaptic input for the integrate-and-fire model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Computer Simulation; gamma-Aminobutyric Acid; Models, Neurological; N-Methylaspartate; Neurotransmitter Agents; Synaptic Transmission | 2001 |
Characterization of the glutamatergic system for induction and maintenance of allodynia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; ATP-Binding Cassette Transporters; Capsaicin; Dinoprost; Dinoprostone; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Pain Measurement; Physical Stimulation; Posterior Horn Cells; Receptors, Glutamate; Synapses; Synaptic Transmission; Touch | 2001 |
Short-term adaptation in the peripheral auditory system is related to the AMPA receptor.
Topics: Adaptation, Physiological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; N-Methylaspartate; Perceptual Masking; Receptors, AMPA | 2001 |
Thalamocortical NMDA conductances and intracortical inhibition can explain cortical temporal tuning.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Excitatory Amino Acid Agonists; Models, Biological; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus; Time Factors; Visual Cortex | 2001 |
Expression and regulation of Na pump isoforms in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cerebellum; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Potassium Radioisotopes; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2001 |
Effects of the calcium release inhibitor dantrolene and the Ca2+-ATPase inhibitor thapsigargin on spinal nociception in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Behavior, Animal; Calcium; Calcium-Transporting ATPases; Dantrolene; Enzyme Inhibitors; Male; Muscle Relaxants, Central; N-Methylaspartate; Pain; Pain Measurement; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Spinal Cord; Substance P; Thapsigargin | 2001 |
Effects of iontophoretically applied substance P, calcitonin gene-related peptide on excitability of dorsal horn neurones in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcitonin Gene-Related Peptide; Excitatory Amino Acid Agonists; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2001 |
Long-term memory formation in the chick requires mobilization of ryanodine-sensitive intracellular calcium stores.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Calcium; Chickens; Dantrolene; Excitatory Amino Acid Agonists; Insecticides; Ion Transport; Memory; Muscle Relaxants, Central; N-Methylaspartate; Prosencephalon; Ryanodine; Synaptosomes | 2001 |
Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Radioisotopes; Excitatory Amino Acid Agonists; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nitric Oxide; Presynaptic Terminals; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptosomes; Tritium | 2001 |
Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and PI3 kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Corpus Striatum; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Wortmannin | 2001 |
The role of the nucleus accumbens in instrumental conditioning: Evidence of a functional dissociation between accumbens core and shell.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Behavior, Animal; Choice Behavior; Conditioning, Classical; Conditioning, Operant; Cues; Female; Food Deprivation; Microinjections; Motivation; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Long-Evans; Satiety Response; Transfer, Psychology | 2001 |
Differential effects of NMDA antagonists microinjections into the nucleus reticularis pontis caudalis on seizures induced by pentylenetetrazol in the rat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Pentylenetetrazole; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures | 2001 |
Potentiation of a metabotropic glutamatergic response following NMDA receptor activation in rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cycloleucine; Excitatory Amino Acid Agonists; Hippocampus; N-Methylaspartate; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Neuroprotective effects of lamotrigine and remacemide on excitotoxicity induced by glutamate agonists in isolated chick retina.
Topics: Acetamides; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; L-Lactate Dehydrogenase; Lamotrigine; N-Methylaspartate; Necrosis; Neuroprotective Agents; Phenethylamines; Retina; Retinal Ganglion Cells; Triazines | 2001 |
Dimethyl sulfoxide suppresses NMDA- and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cells, Cultured; Dimethyl Sulfoxide; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Hippocampus; Ion Transport; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Glutamate | 2001 |
Group II mGlu receptor agonists fail to protect against various neurotoxic insults induced in murine cortical, striatal and cerebellar granular pure neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclic AMP; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hydrogen Peroxide; Immunohistochemistry; Mice; N-Methylaspartate; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxins; Oxidants; Receptors, Glutamate | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels.
Topics: Adenosine Triphosphate; Aldehydes; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyloid beta-Protein Precursor; Animals; Calcium; Cells, Cultured; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Hippocampus; Lipid Peroxidation; Membrane Lipids; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Okadaic Acid; Patch-Clamp Techniques; Phosphorylation; Precipitin Tests; Rats; Receptors, N-Methyl-D-Aspartate; Rotenone; Time Factors; Uncoupling Agents | 2001 |
Biphasic modulation of NMDA-induced responses in pyramidal cells of the medial prefrontal cortex by Y-931, a potential atypical antipsychotic drug.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Phencyclidine; Piperazines; Prefrontal Cortex; Pyramidal Cells; Rats | 2001 |
Hemodynamic effects elicited by microinjection of glutamatergic agonists into NTS of conscious rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine Derivatives; Blood Flow Velocity; Consciousness; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hemodynamics; Male; Microinjections; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Regional Blood Flow; Solitary Nucleus | 2001 |
Huperzine A, a nootropic alkaloid, inhibits N-methyl-D-aspartate-induced current in rat dissociated hippocampal neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Hydrogen-Ion Concentration; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sesquiterpenes; Spermine; Zinc | 2001 |
Glutamate, NMDA, and AMPA induced changes in extracellular space volume and tortuosity in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Chelating Agents; Diffusion; Dizocilpine Maleate; Edema; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Gliosis; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Spinal Cord | 2001 |
NMDA antagonists in the superior colliculus prevent developmental plasticity but not visual transmission or map compression.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Mapping; Cricetinae; Electrophysiologic Techniques, Cardiac; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Mesocricetus; N-Methylaspartate; Neuronal Plasticity; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Visual Fields; Visual Pathways; Visual Perception | 2001 |
Synthesis, ionotropic glutamate receptor binding affinity, and structure-activity relationships of a new set of 4,5-dihydro-8-heteroaryl-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates analogues of TQX-173.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ligands; Male; Mice; N-Methylaspartate; Quinoxalines; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Structure-Activity Relationship; Synaptic Membranes; Triazines | 2001 |
Suppression of presynaptic responses to adenosine by activation of NMDA receptors.
Topics: Action Potentials; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Agonists; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; N-Methylaspartate; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Time Factors; Triazines; Triazoles | 2001 |
Stimulatory effects of centrally injected kainate and N-methyl-D-aspartate on gastric acid secretion in anesthetized rats.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Brain; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gastric Acid; Gastric Mucosa; Kainic Acid; Male; Muscarinic Antagonists; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vagotomy; Vagus Nerve | 2001 |
Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Chick Embryo; Excitatory Amino Acid Agonists; In Situ Nick-End Labeling; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; N-Methylaspartate; Necrosis; Receptors, Glutamate; Retina | 2001 |
The pituitary adenylate cyclase-activating polypeptide modulates glutamatergic calcium signalling: investigations on rat suprachiasmatic nucleus neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cyclic AMP; Drug Interactions; Fluorescent Dyes; Fura-2; Glutamic Acid; N-Methylaspartate; Neurons; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Suprachiasmatic Nucleus | 2001 |
Effect of the group I metabotropic glutamate agonist DHPG on the visual cortex.
Topics: Action Potentials; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Drug Synergism; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; N-Methylaspartate; Organ Culture Techniques; Phenylacetates; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Visual Cortex | 2001 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bridged Bicyclo Compounds; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hallucinogens; Male; N-Methylaspartate; Neural Pathways; Prefrontal Cortex; Pyramidal Cells; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; Receptors, Opioid, mu; Receptors, Serotonin; Serotonin; Synaptic Transmission; Thalamus | 2001 |
Spinal prostaglandins are involved in the development but not the maintenance of inflammation-induced spinal hyperexcitability.
Topics: Action Potentials; Administration, Topical; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carrageenan; Dinoprostone; Excitatory Amino Acid Agonists; Hindlimb; Hyperesthesia; Indomethacin; Inflammation; Injections, Spinal; Iontophoresis; Joints; Kaolin; Male; N-Methylaspartate; Nociceptors; Physical Stimulation; Posterior Horn Cells; Prostaglandins; Rats; Rats, Wistar; Spinal Cord | 2001 |
Nitric oxide produced by non-motoneuron cells enhances rat embryonic motoneuron sensitivity to excitotoxins: comparison in mixed neuron/glia or purified cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Cell Communication; Cell Differentiation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuroglia; Neurotoxins; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Dopamine release in the prefrontal cortex during stress is reduced by the local activation of glutamate receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dicarboxylic Acids; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Synaptic Transmission | 2001 |
Somatostatin release by glutamate in vivo is primarily regulated by AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatostatin | 2001 |
Impaired excitatory transmission in the striatum of rats chronically intoxicated with manganese.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cerebral Cortex; Chronic Disease; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Agonists; Liver; Male; Manganese; Manganese Poisoning; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Reference Values; Synapses; Synaptic Transmission | 2001 |
Intracellular activity of rat spinal cord motoneurons in slices.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Isoquinolines; Male; Motor Neurons; N-Methylaspartate; Neural Conduction; Neurophysiology; Organ Culture Techniques; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 2001 |
Distance-dependent increase in AMPA receptor number in the dendrites of adult hippocampal CA1 pyramidal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dendrites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Microinjections; N-Methylaspartate; Neural Pathways; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2001 |
Excitatory amino acid receptor subtype agonists induce feeding in the nucleus accumbens shell in rats: opioid antagonist actions and interactions with mu-opioid agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Feeding Behavior; Male; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Synaptic Transmission | 2001 |
Magnesium decreases arterial pressure and inhibits cardiovascular responses induced by N-methyl-D-aspartate and metabotropic glutamate receptors stimulation in rostral ventrolateral medulla.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Heart Rate; Magnesium; Magnesium Chloride; Magnesium Sulfate; Male; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2001 |
Rapid and reversible changes in dendrite morphology and synaptic efficacy following NMDA receptor activation: implication for a cellular defense against excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cell Size; Dendrites; Excitatory Amino Acid Agonists; Fluorescent Dyes; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium; Synaptic Transmission; Time Factors | 2001 |
PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholera Toxin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Electrophysiology; Female; gamma-Aminobutyric Acid; Glycine; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Male; N-Methylaspartate; Pain; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, Prostaglandin; Synaptic Transmission | 2002 |
NMDA receptor function in mouse models of Huntington disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Calcium Channels; Calcium Signaling; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Huntington Disease; Immunohistochemistry; Ion Channels; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Mutation; N-Methylaspartate; Neostriatum; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Excitotoxicity-induced expression of amyloid precursor protein (beta-APP) in the hippocampus and cortex of rat brain. an electron-microscopy and biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Dizocilpine Maleate; Hippocampus; Immunohistochemistry; Male; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques | 2001 |
[Autobiographic memory. Neurobiological substrates].
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autobiographies as Topic; Brain; Humans; Male; Memory; N-Methylaspartate | 2001 |
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Protein Isoforms; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines; Type C Phospholipases | 2002 |
alpha 2-Macroglobulin exposure reduces calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Macroglobulins; Animals; Calcium; Calcium Signaling; Cells, Cultured; Hippocampus; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; N-Methylaspartate; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Pathway-specific properties of AMPA and NMDA-mediated transmission in CA1 hippocampal pyramidal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channel Blockers; Cesium; Dendrites; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; N-Methylaspartate; Neural Pathways; Patch-Clamp Techniques; Perforant Pathway; Pyramidal Cells; Rats; Rats, Long-Evans; Sodium Channel Blockers; Synaptic Transmission | 2002 |
Glutamate receptor desensitization block potentiates the stimulated GABA release through external Ca2+-independent mechanisms from granule cells of olfactory bulb.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kinetics; Male; N-Methylaspartate; Neurons; Olfactory Bulb; Potassium Chloride; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2001 |
Different action of memantine and caroverine on glutamatergic transmission in the mammalian cochlea.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Dopamine Agents; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Memantine; N-Methylaspartate; Neurons, Afferent; Quinoxalines | 2002 |
Role of substance P in the peripheral vestibular and auditory system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Auditory Cortex; Cochlea; Hair Cells, Auditory, Inner; Humans; N-Methylaspartate; Substance P; Vestibular Nerve; Vestibule, Labyrinth | 2002 |
Induction and blockade of epileptic foci by intracerebral injection of glutamatergic agonists and antagonists in frerly moving cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cats; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Seizures | 2002 |
Distinct NMDA receptors provide differential modes of transmission at mossy fiber-interneuron synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Chlorides; Cyclopropanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Mossy Fibers, Hippocampal; N-Methylaspartate; Patch-Clamp Techniques; Phenols; Piperidines; Polyamines; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2002 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Mechanisms for lateral turns in lamprey in response to descending unilateral commands: a modeling study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Functional Laterality; Lampreys; Models, Neurological; Motor Activity; N-Methylaspartate; Nerve Net; Spinal Cord | 2002 |
NMDA and AMPA/kainate glutamatergic agonists increase the extracellular concentrations of GABA in the prefrontal cortex of the freely moving rat: modulation by endogenous dopamine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurons; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation | 2002 |
Interactions between GABAergic and aminoacidergic pathways in the control of gonadotropin and GH secretion in pre-pubertal female rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Bicuculline; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Human Growth Hormone; Kainic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Sexual Maturation | 2002 |
Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Hypoglycemic Agents; Immunoblotting; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Phenformin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: implications for synaptic plasticity and excitotoxic neuronal death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Caspase 3; Caspases; Cells, Cultured; Enzyme Activation; Hippocampus; Kinetics; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, AMPA; Recombinant Proteins | 2002 |
Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcineurin; Calcium; Cobalt; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Enzyme Inhibitors; Excitatory Amino Acid Agonists; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Phosphatase 2; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Pyrrolylquinoxalinediones carrying a piperazine residue represent highly potent and selective ligands to the homomeric kainate receptor GluR5.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ligands; Mice; Molecular Structure; N-Methylaspartate; Piperazines; Quinoxalines; Receptors, Kainic Acid; Seizures; Structure-Activity Relationship; Substrate Specificity | 2002 |
Spinal cord heme oxygenase participates in glutamate-induced pain-related behaviors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Heme Oxygenase (Decyclizing); In Vitro Techniques; Injections, Spinal; Male; Mesoporphyrins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Protoporphyrins; Spinal Cord | 2002 |
Glutamate cascade to cAMP response element-binding protein phosphorylation in cultured striatal neurons through calcium-coupled group I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Drug Interactions; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Phosphorylation; Rats; Receptors, Metabotropic Glutamate; Type C Phospholipases | 2002 |
Rat motoneuron cell death in development correlates with loss of N-methyl-D-aspartate receptors.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Death; Electric Conductivity; Excitatory Amino Acid Agonists; Fluorescence; In Vitro Techniques; Iontophoresis; Isoquinolines; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2002 |
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Molsidomine; N-Methylaspartate; Nerve Degeneration; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Wistar; Tritium | 2002 |
Facilitation of glutamate release by ionotropic glutamate receptors in osteoblasts.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Division; Cells, Cultured; Glutamic Acid; Kainic Acid; N-Methylaspartate; Osteoblasts; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; Skull | 2002 |
Physiological and anatomical properties of the suprachiasmatic nucleus of an anophthalmic mouse.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anophthalmos; Bicuculline; Blindness; Calcium; Circadian Rhythm; Electrophysiology; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Magnesium; Mice; Mice, Mutant Strains; N-Methylaspartate; Organ Culture Techniques; Suprachiasmatic Nucleus | 2002 |
Chronic multichannel recordings from organotypic hippocampal slice cultures: protection from excitotoxic effects of NMDA by non-competitive NMDA antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Dizocilpine Maleate; Electrodes, Implanted; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Memantine; N-Methylaspartate; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2002 |
Carbon monoxide and metabotropic glutamate receptors in rat nucleus tractus solitarii: participation in cardiovascular effect.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Carbon Monoxide; Cardiovascular System; Cycloleucine; Deuteroporphyrins; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Heme Oxygenase (Decyclizing); Hemin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Solitary Nucleus | 2002 |
Site-selective N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonists produce distinct effects in rats performing complex discriminations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Memory; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Calcium; Calmodulin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Feedback; Female; Glutamic Acid; Imidazoles; Imines; Isoenzymes; Isoproterenol; Isoquinolines; Kainic Acid; Male; Mice; N-Methylaspartate; Nerve Tissue Proteins; Propranolol; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Presynaptic; Second Messenger Systems; Sulfonamides; Synaptic Transmission; Trifluoperazine | 2003 |
Neurokinin release in the rat nucleus of the solitary tract via NMDA and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurokinin A; Neurokinin B; Presynaptic Terminals; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Solitary Nucleus; Substance P; Synaptic Transmission; Vagus Nerve; Visceral Afferents | 2002 |
Glutamatergic and serotonergic mechanisms in the dorsal facial area for common carotid artery blood flow control in the cat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Blood Flow Velocity; Blood Pressure; Carotid Artery, Common; Cats; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Glutamates; Glutamic Acid; Heart Rate; Ketanserin; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, AMPA; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cations; Electrophysiology; Excitatory Amino Acid Agonists; Ion Channel Gating; Luminescent Proteins; Models, Biological; Molecular Sequence Data; Mutation; N-Methylaspartate; Neurons, Afferent; Physical Stimulation; Protein Subunits; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Signal Transduction; Stimulation, Chemical | 2002 |
Corticospinal transmission to motoneurons in cervical spinal cord slices from adult rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Iontophoresis; Male; Motor Neurons; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Wistar; Spinal Cord; Synaptic Transmission | 2002 |
Effects of calcium and glutamate receptor agonists on leaf consumption by lepidopteran neonates.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Feeding Behavior; Kainic Acid; Lepidoptera; N-Methylaspartate; Plant Leaves | 2003 |
Effect of nitric oxide on excitatory amino acid-evoked discharge of neurons in NTS.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Excitatory Amino Acids; Hydrazines; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Vagus Nerve | 2003 |
Bidirectional synaptic plasticity in the cerebellum-like mammalian dorsal cochlear nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cochlear Nucleus; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses | 2003 |
Chronic NMDA receptor blockade from birth delays the maturation of NMDA currents, but does not affect AMPA/kainate currents.
Topics: Adaptation, Physiological; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Kainic Acid; N-Methylaspartate; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses | 2003 |
Involvement of acetylated tubulin in the regulation of Na+,K+ -ATPase activity in cultured astrocytes.
Topics: Acetylation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ionophores; Mice; Monensin; N-Methylaspartate; Sodium-Potassium-Exchanging ATPase; Tubulin | 2003 |
Effects of intra-accumbens focal administrations of glutamate antagonists on object recognition memory in mice.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Mapping; Discrimination Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Form Perception; Male; Mental Recall; Mice; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Quinoxalines | 2003 |
5-HT1 and 5-HT2 receptor activation reduces N-methyl-D-aspartate (NMDA)-stimulated LH secretion in prepubertal male and female rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Biguanides; Excitatory Amino Acid Agonists; Female; Fenclonine; Luteinizing Hormone; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Maturation | 2003 |
Common molecular and cellular substrates of addiction and memory.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Hippocampus; Humans; Limbic System; Memory Disorders; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Substance-Related Disorders | 2002 |
Activity-dependent role of NMDA receptors in transmission of cardiac mechanoreceptor input to the NTS.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dogs; Drug Administration Routes; Heart; Mechanoreceptors; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synaptic Transmission | 2003 |
Dendritic glutamate-induced bursting in the prefrontal cortex: further characterization and effects of phencyclidine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Hallucinogens; Ketamine; Lysine; Male; Membrane Potentials; N-Methylaspartate; Phencyclidine; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2003 |
Regulation of orexin neurons by the monoaminergic and cholinergic systems.
Topics: Acetylcholine; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carrier Proteins; Electrophysiology; Female; Gene Expression Regulation; Green Fluorescent Proteins; Intracellular Signaling Peptides and Proteins; Luminescent Proteins; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Orexins; Patch-Clamp Techniques | 2003 |
Olanzapine and clozapine but not haloperidol reverse subchronic phencyclidine-induced functional hyperactivity of N-methyl-D-aspartate receptors in pyramidal cells of the rat medial prefrontal cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Haloperidol; Male; Membrane Potentials; N-Methylaspartate; Olanzapine; Patch-Clamp Techniques; Phencyclidine; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2003 |
Spinal gabapentin and antinociception: mechanisms of action.
Topics: Acetates; Adrenergic alpha-Antagonists; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amines; Analgesics; Animals; Atropine; Cyclohexanecarboxylic Acids; Dihydroergocristine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Thapsigargin; Triazoles | 2003 |
The GABAA receptor agonist THIP is neuroprotective in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Hippocampus; Isoxazoles; Kainic Acid; Muscimol; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Propidium; Pyramidal Cells; Rats; Rats, Wistar; Time Factors | 2003 |
Ethanol withdrawal hyper-responsiveness mediated by NMDA receptors in spinal cord motor neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic AMP-Dependent Protein Kinases; Ethanol; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance Withdrawal Syndrome | 2003 |
Reverse microdialysis of ionotropic glutamate receptor agonists in the rat globus pallidus increased extracellular dopamine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Excitatory Amino Acid Agonists; Extracellular Space; Globus Pallidus; Male; Microdialysis; N-Methylaspartate; Rats | 2003 |
17beta-estradiol inhibits excitatory amino acid-induced activity of neurons of the nucleus tractus solitarius.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Depression, Chemical; Estradiol; Excitatory Amino Acids; Female; GABA Antagonists; Immunohistochemistry; Iontophoresis; N-Methylaspartate; Neurons; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Solitary Nucleus | 2003 |
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Nerves | 2003 |
Differential modulation of NMDA-induced calcium transients by arachidonic acid and nitric oxide in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Arachidonic Acid; Cadmium; Calcium; Cells, Cultured; Drug Interactions; Eicosanoic Acids; Eicosapentaenoic Acid; Excitatory Amino Acid Agonists; Fatty Acids, Unsaturated; Free Radical Scavengers; Fura-2; Hippocampus; N-Methylaspartate; Nitric Oxide; Pyramidal Cells; Rats; Time Factors | 2003 |
Inhibition of glutamate-induced nitric oxide synthase activation by dopamine in cultured rat retinal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dopamine; Dopamine Agonists; Enzyme Activation; Excitatory Amino Acid Agonists; Kainic Acid; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Retina | 2003 |
Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Caspases; Cells, Cultured; Cytochrome c Group; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Mitochondria; N-Methylaspartate; Necrosis; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Superoxide Dismutase; Superoxides | 2003 |
Effect of excitatory amino acid receptor agonists on penile erection after administration into paraventricular nucleus of hypothalamus in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley | 2003 |
Different phosphatase-dependent mechanisms mediate long-term depression and depotentiation of long-term potentiation in mouse hippocampal CA1 area.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Neural Inhibition; Okadaic Acid; Phosphoric Monoester Hydrolases; Presynaptic Terminals; Tacrolimus; Time Factors | 2003 |
Regulation of persistent activity by background inhibition in an in vitro model of a cortical microcircuit.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; In Vitro Techniques; N-Methylaspartate; Nerve Net; Neural Inhibition; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2003 |
Distinct quantal features of AMPA and NMDA synaptic currents in hippocampal neurons: implication of glutamate spillover and receptor saturation.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dendrites; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Membrane Potentials; Models, Neurological; Models, Statistical; N-Methylaspartate; Pyramidal Cells; Quantum Theory; Rats; Rats, Wistar; Synaptic Transmission | 2003 |
Multiplicative gain changes are induced by excitation or inhibition alone.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Computer Simulation; Electric Stimulation; GABA Antagonists; Models, Neurological; N-Methylaspartate; Neurons; Reproducibility of Results; Synaptic Transmission; Visual Cortex | 2003 |
Effect of excess extracellular glutamate on dendrite growth from cerebral cortical neurons at 3 days in vitro: Involvement of NMDA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Embryo, Mammalian; Excitatory Amino Acid Agonists; Extracellular Fluid; Glutamic Acid; Immunohistochemistry; Mice; Mice, Inbred BALB C; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2003 |
Neurons derived from embryonic stem (ES) cells resemble normal neurons in their vulnerability to excitotoxic death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Lineage; Cell Survival; Cells, Cultured; Coculture Techniques; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Glutamic Acid; Immunohistochemistry; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stem Cells | 2003 |
Chronic nicotine causes functional upregulation of ionotropic glutamate receptors mediating hippocampal noradrenaline and striatal dopamine release.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Excitatory Amino Acid Agonists; Hippocampus; Male; N-Methylaspartate; Neostriatum; Nicotine; Nicotinic Agonists; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Up-Regulation | 2004 |
Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anilides; Aniline Compounds; Animals; Calcium; Capsaicin; Carrier Proteins; Cell Line; Cinnamates; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hot Temperature; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Membrane Potentials; N-Methylaspartate; Neuropeptides; Norepinephrine; Orexins; Patch-Clamp Techniques; Protein Binding; Radioligand Assay; Rats; Receptors, Drug; Serotonin Receptor Agonists; Xanthenes | 2004 |
The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors | 2004 |
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dizocilpine Maleate; Female; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain Threshold; Propofol; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Endocannabinoids mediate presynaptic inhibition of glutamatergic transmission in rat ventral tegmental area dopamine neurons through activation of CB1 receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoxazines; Cannabinoid Receptor Modulators; Cells, Cultured; Dopamine; Endocannabinoids; Excitatory Amino Acid Agonists; Glutamine; Male; Morpholines; N-Methylaspartate; Naphthalenes; Neural Inhibition; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Synaptic Transmission; Ventral Tegmental Area | 2004 |
Activation of ionotropic glutamate receptors on peripheral axons of primary motoneurons mediates transmitter release at the zebrafish NMJ.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dimethyl Sulfoxide; Motor Neurons; N-Methylaspartate; Neuromuscular Junction; Peripheral Nerves; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Zebrafish | 2004 |
Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Culture Techniques; Gene Deletion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2004 |
Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Cellular Senescence; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Eye Proteins; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Picrotoxin; Receptors, AMPA; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Taurine | 2004 |
How the shape of pre- and postsynaptic signals can influence STDP: a biophysical model.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biophysical Phenomena; Biophysics; Electric Stimulation; Excitatory Amino Acid Agonists; Humans; Learning; Models, Neurological; N-Methylaspartate; Neural Conduction; Neuronal Plasticity; Synapses; Synaptic Transmission; Time Factors | 2004 |
Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Corpus Striatum; Drug Administration Schedule; Fungicides, Industrial; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Remoxipride; Substance Withdrawal Syndrome; Time Factors; Triazoles | 2004 |
NMDA receptors in nucleus tractus solitarii are linked to soluble guanylate cyclase.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminoquinolines; Animals; Baroreflex; Biotransformation; Blood Pressure; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; In Vitro Techniques; Male; Microinjections; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Stereotaxic Techniques | 2004 |
AMPA, not NMDA, activates RhoA GTPases and subsequently phosphorylates moesin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Line; Excitatory Amino Acid Agonists; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kainic Acid; Microfilament Proteins; N-Methylaspartate; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; rho-Associated Kinases; rhoA GTP-Binding Protein | 2004 |
A proportional but slower NMDA potentiation follows AMPA potentiation in LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine; Visual Cortex | 2004 |
Effect of 4-aminopyridine on synaptic transmission in rat hippocampal slices.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Rats; Synaptic Transmission; Time Factors | 2004 |
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.
Topics: Activating Transcription Factor 1; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies, Monoclonal; Association Learning; Behavior, Animal; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Carrier Proteins; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; DNA-Binding Proteins; Excitatory Amino Acid Agonists; Fear; gag Gene Products, Human Immunodeficiency Virus; Gene Expression Regulation; Gene Products, gag; Immunohistochemistry; In Vitro Techniques; Lamin Type B; Long-Term Potentiation; Membrane Potentials; Membrane Proteins; Memory Disorders; Mice; Mice, Knockout; Microtubule-Associated Proteins; N-Methylaspartate; Neurodegenerative Diseases; Neuronal Plasticity; Patch-Clamp Techniques; Precipitin Tests; Presenilin-1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors; Viral Proteins | 2004 |
Increased neurotransmitter release during long-term potentiation at mossy fibre-granule cell synapses in rat cerebellum.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cytoplasmic Granules; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; N-Methylaspartate; Nerve Fibers; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Rats; Synapses; Synaptic Transmission | 2004 |
Extracellular taurine in the substantia nigra: taurine-glutamate interaction.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Chemistry; Calcium; Chelating Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Antagonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Ketamine; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Substantia Nigra; Taurine; Time Factors; Zinc | 2004 |
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Administration Routes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Hindlimb; Kainic Acid; Lumbosacral Region; Male; Microdialysis; Motor Neurons; N-Methylaspartate; Paralysis; Perfusion; Potassium; Potassium Channel Blockers; Rats; Receptors, AMPA; Spinal Cord | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Central Nervous System Stimulants; Dopamine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synapses; Time Factors; Transferrin; Ventral Tegmental Area | 2004 |
Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Line; Female; Humans; Kainic Acid; Kinetics; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Nerve Fibers; Protein Subunits; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid; Spinal Nerve Roots | 2004 |
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Dopamine-glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction | 2004 |
Glutamate-induced elevations in intracellular chloride concentration in hippocampal cell cultures derived from EYFP-expressing mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Angiogenesis Inhibitors; Animals; Animals, Newborn; Bacterial Proteins; Benzopyrans; Bicuculline; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Furosemide; GABA Antagonists; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; Intracellular Space; Luminescent Proteins; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Mice, Transgenic; N-Methylaspartate; Naphthols; Neurons; Nitrobenzoates; Potassium; Rhodamines; Time Factors | 2004 |
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium | 2004 |
Subunit rules governing the sorting of internalized AMPA receptors in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytoplasm; Endocytosis; Excitatory Amino Acid Agonists; Hippocampus; Intracellular Membranes; Lysosomes; N-Methylaspartate; Neurons; Protein Isoforms; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Small Interfering; Synapses; Tissue Distribution | 2004 |
Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Northern; Body Weight; Chronic Disease; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Organ Size; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Time Factors | 2004 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
Influx of extracellular calcium regulates actin-dependent morphological plasticity in dendritic spines.
Topics: Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caffeine; Calcium; Cells, Cultured; Dendrites; Hippocampus; N-Methylaspartate; Neuronal Plasticity; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Amino Acids; Animals; Aspartic Acid; Dicarboxylic Acids; Drug Interactions; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 2004 |
Protection of auditory function against noise trauma with local caroverine administration in guinea pigs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Threshold; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hearing Loss, Noise-Induced; Male; N-Methylaspartate; Noise; Quinoxalines; Random Allocation; Receptors, Glutamate | 2004 |
Pregnenolone sulfate enhances long-term potentiation in CA1 in rat hippocampus slices through the modulation of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Pregnenolone; Rats; Receptors, N-Methyl-D-Aspartate | 2004 |
BDNF enhancement of postsynaptic NMDA receptors is blocked by ethanol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Central Nervous System Depressants; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Membrane Potentials; Mice; N-Methylaspartate; Neocortex; Patch-Clamp Techniques; Phenols; Piperidines; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 2005 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cell Size; Circadian Rhythm; Cytochalasin D; Cytoskeleton; Dicarboxylic Acids; Dopamine; Eye Proteins; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; N-Methylaspartate; Neuroglia; Neurons; Nocodazole; Potassium; Pyrrolidines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Xanthenes | 2004 |
Electrophysiological and neurochemical characterization of neurons of the medial preoptic area in Japanese quail (Coturnix japonica).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Coturnix; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Isonicotinic Acids; Kainic Acid; Male; N-Methylaspartate; Neurons; Norepinephrine; Preoptic Area; Pyridazines; Sympathomimetics | 2004 |
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.
Topics: Active Transport, Cell Nucleus; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Caspases; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cysteine Proteinase Inhibitors; Cytochromes c; DNA Damage; Enzyme Activation; Excitatory Amino Acid Agonists; Flavoproteins; Genes, bcl-2; Glutamic Acid; Injections; Intracellular Membranes; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Mitochondria; N-Methylaspartate; Neurons; Nitric Oxide; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Transfection | 2004 |
Transient Ca2+-permeable AMPA receptors in postnatal rat primary auditory neurons.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzodiazepines; Blotting, Western; Calcium; Cobalt; Cochlea; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Glycine; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neurons; Parvalbumins; Peptides, Cyclic; Permeability; Rats; Rats, Wistar; Receptors, AMPA; Spider Venoms | 2004 |
Transiently higher release probability during critical period at thalamocortical synapses in the mouse barrel cortex: relevance to differential short-term plasticity of AMPA and NMDA EPSCs and possible involvement of silent synapses.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Critical Period, Psychological; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Mice, Inbred C57BL; Models, Neurological; N-Methylaspartate; Neuronal Plasticity; Neurons; Somatosensory Cortex; Synapses; Synaptic Transmission; Time Factors | 2004 |
Dopamine and GABA increases produced by activation of glutamate receptors in the nucleus accumbens are decreased during aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorometry; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Glutamate | 2005 |
Effect of excitatory amino acid receptor agonists on penile erection after administration into the CA3 hippocampal region in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Hippocampus; Male; N-Methylaspartate; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2004 |
Nitric oxide modulation of glutamatergic, baroreflex, and cardiopulmonary transmission in the nucleus of the solitary tract.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Biguanides; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heart; Heart Rate; Kidney; Lung; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Sympathetic Nervous System; Synaptic Transmission | 2005 |
Modulatory effects mediated by metabotropic glutamate receptor 5 on lateral geniculate nucleus relay cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Cats; Drug Interactions; Female; Geniculate Bodies; Glycine; Iontophoresis; Male; N-Methylaspartate; Neurons; Phenylacetates; Photic Stimulation; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2005 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
Potentiation of spinal N-methyl-D-aspartate-mediated nociceptive transmission by cocaine-regulated and amphetamine-regulated transcript peptide in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Hyperalgesia; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Pain Measurement; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2005 |
Self-administration enhances excitatory synaptic transmission in the bed nucleus of the stria terminalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Food Preferences; In Vitro Techniques; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Septal Nuclei; Synaptic Transmission | 2005 |
Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamic Acid; Injections, Subcutaneous; Male; Morphine; N-Methylaspartate; Nucleus Accumbens; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Tritium | 2005 |
Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incisional pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Neuronal Plasticity; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; D-Aspartic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Oocytes; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Complementary; Stereoisomerism; Xenopus laevis | 2005 |
Supraspinal and spinal alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid and N-methyl-D-aspartate glutamatergic control of the micturition reflex in the urethane-anesthetized rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Anesthetics, Intravenous; Animals; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electromyography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Injections, Intraventricular; Injections, Spinal; Isoquinolines; N-Methylaspartate; Neural Pathways; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrazoles; Urethane; Urinary Bladder; Urination | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness | 2005 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamin Type B; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Valine | 2005 |
Long-term potentiation of silent synapses in substantia gelatinosa neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Chelating Agents; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Magnesium; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synapses | 2005 |
Spine-neck geometry determines NMDA receptor-dependent Ca2+ signaling in dendrites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendritic Spines; Diagnostic Imaging; Dose-Response Relationship, Radiation; Glutamates; Hippocampus; In Vitro Techniques; Indoles; Lasers; Membrane Potentials; Models, Neurological; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine | 2005 |
Rap2-JNK removes synaptic AMPA receptors during depotentiation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Long-Term Synaptic Depression; Magnesium; Models, Neurological; Mutagenesis; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; rap GTP-Binding Proteins; Rats; Receptors, AMPA; Recombinant Proteins; Synaptic Transmission; Time Factors; Transfection; Valine | 2005 |
Depressor responses to L-proline microinjected into the rat ventrolateral medulla are mediated by ionotropic excitatory amino acid receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Proline; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2005 |
Encoding and decoding of dendritic excitation during active states in pyramidal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; N-Methylaspartate; Neocortex; Pyramidal Cells; Rats; Rats, Wistar | 2005 |
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Casein Kinase 1 epsilon; Casein Kinase I; Casein Kinase Ialpha; Casein Kinase Idelta; Corpus Striatum; Egtazic Acid; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 2005 |
GABAergic signaling to newborn neurons in dentate gyrus.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Dentate Gyrus; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Flow Cytometry; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neural Inhibition; Neurons; Parvalbumins; Patch-Clamp Techniques; Pro-Opiomelanocortin; Protein Subunits; Pyridazines; Pyridines; Receptors, GABA-A; Signal Transduction; Synapses; Synaptic Transmission; Zolpidem | 2005 |
Frequency-dependent impairment of hippocampal LTP from NMDA receptors with reduced calcium permeability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Integrases; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Inhibition of rho-kinase in the nucleus tractus solitarius enhances glutamate sensitivity in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amides; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Injections; Intracellular Signaling Peptides and Proteins; Iontophoresis; Male; N-Methylaspartate; Neurons; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Solitary Nucleus | 2005 |
Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cell Survival; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Pertussis Toxin; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
Release kinetics, quantal parameters and their modulation during short-term depression at a developing synapse in the rat CNS.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Stem; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kinetics; N-Methylaspartate; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles | 2005 |
Inhibitory glutamate receptors in spider peripheral mechanosensory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; beta-Alanine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Excitatory Amino Acid Agonists; GABA Agonists; Glutamic Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Muscimol; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Physical Stimulation; Receptors, Glutamate; Sense Organs; Spiders | 2005 |
Silent synapses in a thalamo-cortical circuit necessary for song learning in zebra finches.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Finches; In Vitro Techniques; Learning; Lysine; Membrane Potentials; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Patch-Clamp Techniques; Quinoxalines; Synapses; Thalamus; Vocalization, Animal | 2005 |
Effects of synaptic activity on dendritic spine motility of developing cortical layer v pyramidal neurons.
Topics: Actins; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Cell Movement; Cerebral Cortex; Dendrites; Excitatory Amino Acid Agonists; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Mice; Mice, Transgenic; Microscopy, Confocal; N-Methylaspartate; Nerve Net; Peptide Fragments; Potassium Chloride; Pyramidal Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2006 |
Ionotropic glutamate receptors mediate excitatory drive to caudal medullary expiratory neurons in the rabbit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Electromyography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Neurons; Phrenic Nerve; Rats; Receptors, Kainic Acid; Reflex; Respiratory Center | 2005 |
Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bradykinin; Drug Synergism; Glutamic Acid; Hyperalgesia; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Pain; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Spinal Cord; Synaptic Transmission | 2005 |
Mitochondrial superoxide production and MnSOD activity after exposure to agonist and antagonists of ionotropic glutamate receptors in hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Injections; Kainic Acid; Mitochondria; N-Methylaspartate; Rats; Receptors, Kainic Acid; Superoxide Dismutase; Superoxides; Time Factors | 2005 |
GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basic Helix-Loop-Helix Transcription Factors; Bicuculline; Bromodeoxyuridine; Calbindins; Calcium; Cell Count; Cell Differentiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Green Fluorescent Proteins; Hippocampus; History, Ancient; Immunohistochemistry; In Vitro Techniques; Intermediate Filament Proteins; Ki-67 Antigen; Membrane Potentials; Mice; Mice, Transgenic; Microscopy, Immunoelectron; N-Methylaspartate; Nerve Tissue Proteins; Nestin; Neural Cell Adhesion Molecule L1; Neurons; Nickel; Patch-Clamp Techniques; Phosphopyruvate Hydratase; Potassium Channel Blockers; S100 Calcium Binding Protein G; Sialic Acids; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Stem Cells; Tetrodotoxin; Vesicular Inhibitory Amino Acid Transport Proteins | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Rapid control of brain aromatase activity by glutamatergic inputs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Brain; Coturnix; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate | 2006 |
NMDA/AMPA ratio impacts state transitions and entrainment to oscillations in a computational model of the nucleus accumbens medium spiny projection neuron.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Nonlinear Dynamics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Synapses | 2005 |
Neuroprotective effect of Chuk-Me-Sun-Dan on NMDA- and AMPA-evoked nitric oxide synthase activity in mouse brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Mice; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide Synthase; Plant Extracts; Receptors, Glutamate | 2005 |
Synaptic fatigue at the naive perforant path-dentate granule cell synapse in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Perforant Pathway; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles | 2005 |
Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Freund's Adjuvant; Functional Laterality; Immunohistochemistry; Iontophoresis; Male; Microscopy, Immunoelectron; N-Methylaspartate; Neuronal Plasticity; Neurons; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Time Factors | 2005 |
Respiratory and autonomic responses to microinjection of NMDA and AMPA into the commissural subnucleus of the NTS of awake rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Apnea; Autonomic Nervous System; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Microinjections; N-Methylaspartate; Random Allocation; Rats; Rats, Wistar; Respiration; Solitary Nucleus | 2005 |
Anatomical evidence for glutamatergic transmission in primary sensory neurons and onto postganglionic neurons controlling penile erection in rats: an ultrastructural study with neuronal tracing and immunocytochemistry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ganglia, Spinal; Glutamic Acid; Immunohistochemistry; Lumbosacral Region; Male; Microscopy, Electron, Transmission; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 2006 |
Glutamatergic neurotransmission expression profiling in the mouse hippocampus after perforant-path transection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; DNA, Complementary; Down-Regulation; Gene Expression Profiling; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Immunoblotting; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nucleic Acid Amplification Techniques; Oligonucleotide Array Sequence Analysis; Perforant Pathway; Synaptic Transmission | 2005 |
Maintenance of presynaptic function by AMPA receptor-mediated excitatory postsynaptic activity in adult brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Binding Sites; Brain; Calcium; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Motor Activity; N-Methylaspartate; Neurons; Polyvinyls; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Sodium; Synapses; Tetrodotoxin; Time Factors | 2005 |
Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Brain Ischemia; Cell Death; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Excitatory Amino Acid Agonists; Infarction, Middle Cerebral Artery; Interleukin 1 Receptor Antagonist Protein; Male; Mice; Mice, Knockout; Microglia; N-Methylaspartate; Neurons; Neuroprotective Agents; Perfusion; Sialoglycoproteins | 2006 |
Mapping glutamate responses in immunocytochemically identified neurons of the mouse retina.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Count; Excitatory Amino Acids; Kainic Acid; Lewis X Antigen; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Receptors, Glutamate; Retina; Tissue Distribution | 2006 |
Altered cortical glutamate receptor function in the R6/2 model of Huntington's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Benzothiadiazines; Cerebral Cortex; Disease Models, Animal; Exons; Huntington Disease; Magnesium; Mice; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Receptors, Glutamate; Time Factors | 2006 |
Protective effect of donepezil in primary-cultured rat cortical neurons exposed to N-methyl-d-aspartate (NMDA) toxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Indans; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Neuroprotective Agents; Nootropic Agents; Piperidines; Rats; Rats, Wistar; Receptors, Glutamate | 2006 |
Metabotropic glutamate receptors modulate the NMDA- and AMPA-induced gene expression in neocortical interneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotin; Blotting, Northern; Cyclic AMP Response Element-Binding Protein; Electrophysiology; Enkephalins; Excitatory Amino Acid Agonists; Gene Expression; Immunohistochemistry; In Situ Hybridization; Interneurons; N-Methylaspartate; Neocortex; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Protein Precursors; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Cell Surface; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2006 |
A novel role for calcium-independent phospholipase A in alpha-amino-3-hydroxy-5-methylisoxazole-propionate receptor regulation during long-term potentiation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acids; Blotting, Western; Calcium; Drug Interactions; Electric Stimulation; Gene Expression Regulation; Hippocampus; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Naphthalenes; Neurons; Organophosphonates; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phospholipases A; Protein Binding; Protein Isoforms; Pyrones; Rats; Receptors, AMPA; Synaptic Transmission; Time Factors | 2006 |
Distinct transmitter release properties determine differences in short-term plasticity at functional and silent synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caffeine; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Rats; Rats, Wistar; Ryanodine; Synapses | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Kynurenic acid synthesis in bovine retinal slices--effect of glutamate agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cattle; Excitatory Amino Acid Agonists; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Organ Culture Techniques; Retina | 2006 |
Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Isoquinolines; Mice; Microscopy, Video; N-Methylaspartate; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Signal Transduction; Sulfonamides; Suprachiasmatic Nucleus | 2006 |
NMDA-NR1 and AMPA-GluR4 receptor subunit immunoreactivities in the absence epileptic WAG/Rij rat.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anterior Thalamic Nuclei; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Immunohistochemistry; Male; N-Methylaspartate; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 2006 |
Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Hippocampus; Hypoglycemia; Hypoxia; In Vitro Techniques; N-Methylaspartate; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Time Factors | 2006 |
Orexin: a gatekeeper of addiction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Intracellular Signaling Peptides and Proteins; N-Methylaspartate; Neurons; Neuropeptides; Orexins; Rats; Substance-Related Disorders; Ventral Tegmental Area | 2006 |
Role of efficient neurotransmitter release in barrel map development.
Topics: Adenylyl Cyclases; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Brain Mapping; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; GTP-Binding Proteins; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Models, Neurological; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Neurotransmitter Agents; Patch-Clamp Techniques; Somatosensory Cortex; Synapsins; Thalamus; Time Factors | 2006 |
Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors I. Behavioral effects of glutamate and its selective receptor agonists AMPA, NMDA and kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Female; Hypothalamus; Kainic Acid; N-Methylaspartate; Ovariectomy; Rats; Rats, Long-Evans; Receptors, Glutamate; Sexual Behavior, Animal | 2006 |
The antiallodynic effect of NMDA antagonists in neuropathic pain outlasts the duration of the in vivo NMDA antagonism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cold Temperature; Constriction, Pathologic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fentanyl; Iontophoresis; Ketamine; Male; Motor Activity; N-Methylaspartate; Pain; Peripheral Nervous System Diseases; Phthalazines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2006 |
Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors.
Topics: Action Potentials; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression; Immunohistochemistry; Male; Mice; Mice, Transgenic; N-Methylaspartate; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synapses; Time Factors | 2006 |
Contribution of AMPA and NMDA receptors to early and late phases of LTP in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors | 2006 |
Rapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Dizocilpine Maleate; DNA Repair Enzymes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Fluorescent Antibody Technique; Gamma Rays; Gene Expression; Histones; Hydrogen Peroxide; MRE11 Homologue Protein; N-Methylaspartate; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2006 |
Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neuroprotective Agents; Nociceptors; Pain; Receptors, Glutamate; Spinal Cord | 2006 |
The properties and implications of NMDA spikes in neocortical pyramidal cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Models, Neurological; N-Methylaspartate; Neocortex; Neural Inhibition; Pyramidal Cells | 2006 |
Stimulation of the hippocampal glutamate receptor systems induces stress-like responses.
Topics: Acetylcholine; Adrenocorticotropic Hormone; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Behavior, Animal; Blood Glucose; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Hippocampus; Male; Microinjections; N-Methylaspartate; Neostigmine; Rats; Rats, Wistar; Receptors, Glutamate; Stress, Physiological | 2006 |
Motherhood-induced memory improvement persists across lifespan in rats but is abolished by a gestational stress.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Electrophysiology; Female; Hippocampus; Learning; Life Expectancy; Male; Memory; Mothers; N-Methylaspartate; Neuronal Plasticity; Pregnancy; Rats; Rats, Wistar; Stress, Psychological | 2006 |
NMDA and non-NMDA receptors stimulation causes differential oxidative stress in rat cortical slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence | 2006 |
Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Administration, Oral; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Behavior, Animal; Cell Hypoxia; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Maze Learning; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Topiramate | 2006 |
Ultrastructural localisation and differential agonist-induced regulation of AMPA and kainate receptors present at the presynaptic active zone and postsynaptic density.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Down-Regulation; Excitatory Amino Acid Agonists; Glutamic Acid; Microscopy, Electron, Transmission; N-Methylaspartate; Organ Culture Techniques; Presynaptic Terminals; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Synapses; Synaptic Membranes; Synaptic Transmission; Synaptosomes; Up-Regulation | 2006 |
Brain-derived neurotrophic factor and neurotrophin receptors modulate glutamate-induced phase shifts of the suprachiasmatic nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Brain-Derived Neurotrophic Factor; Carbazoles; Circadian Rhythm; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Indole Alkaloids; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, Nerve Growth Factor; Suprachiasmatic Nucleus | 2006 |
Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.
Topics: ADAM Proteins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cell Line; Cerebellar Cortex; Cerebral Cortex; Disks Large Homolog 4 Protein; Epilepsies, Partial; Hippocampus; Humans; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Mice; N-Methylaspartate; Nerve Tissue Proteins; Protein Binding; Protein Structure, Tertiary; Proteins; Rats; Receptors, AMPA; Recombinant Fusion Proteins; Synapses; Synaptic Transmission; Transfection | 2006 |
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biotinylation; Blotting, Western; Cytoskeletal Proteins; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Models, Biological; Mutagenesis; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Okadaic Acid; Patch-Clamp Techniques; Rats; Receptors, AMPA; RNA Interference; Statistics, Nonparametric; Synaptic Transmission; Time Factors | 2006 |
Excitotoxic protection by polyanionic polysaccharide: evidence of a cell survival pathway involving AMPA receptor-MAPK Interactions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Dextran Sulfate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Hippocampus; Immunoblotting; Mitogen-Activated Protein Kinase Kinases; N-Methylaspartate; Neurons; Neuroprotective Agents; Organ Culture Techniques; Polyelectrolytes; Polymers; Polysaccharides; Rats; Receptors, AMPA | 2007 |
Long-term depression requires postsynaptic AMPA GluR2 receptor in adult mouse cingulate cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Gyrus Cinguli; In Vitro Techniques; Lidocaine; Long-Term Synaptic Depression; Male; Membrane Potentials; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuronal Plasticity; Oligopeptides; Patch-Clamp Techniques; Protein Structure, Tertiary; Pyramidal Cells; Receptors, AMPA; Synaptic Transmission; Time Factors | 2007 |
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia | 2007 |
Reduced presynaptic efficiency of excitatory synaptic transmission impairs LTP in the visual cortex of BDNF-heterozygous mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Calcium; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Quinoxalines; Synaptic Transmission; Time Factors; Visual Cortex | 2006 |
Enhanced visual activity in vivo forms nascent synapses in the developing retinotectal projection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Chemistry; Data Interpretation, Statistical; Electrophysiology; Excitatory Postsynaptic Potentials; Larva; N-Methylaspartate; Neurons; Photic Stimulation; Retina; Superior Colliculi; Synapses; Synaptic Transmission; Visual Pathways; Xenopus laevis | 2007 |
Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Calbindins; Computer Simulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Integrases; Interneurons; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; N-Methylaspartate; Parvalbumins; Patch-Clamp Techniques; Receptors, Glutamate; S100 Calcium Binding Protein G | 2007 |
The role of physiological afferent nerve activity during in vivo maturation of the calyx of Held synapse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Auditory Pathways; Calcium; Calcium Channels, L-Type; Down-Regulation; Electric Stimulation; Excitatory Amino Acid Agonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons, Afferent; Patch-Clamp Techniques; Presynaptic Terminals; Synaptic Transmission; Time Factors | 2007 |
Developmental homeostasis of mouse retinocollicular synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Mapping; Excitatory Amino Acid Agonists; Homeostasis; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neurons; Receptors, Nicotinic; Retina; Superior Colliculi; Synapses; Visual Cortex; Visual Pathways | 2007 |
Selective shunting of the NMDA EPSP component by the slow afterhyperpolarization in rat CA1 pyramidal neurons.
Topics: Adrenergic beta-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Time Factors | 2007 |
Chronic intermittent hypoxia alters NMDA and AMPA-evoked currents in NTS neurons receiving carotid body chemoreceptor inputs.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carotid Body; Cells, Cultured; Chemoreceptor Cells; Dose-Response Relationship, Drug; Evoked Potentials; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2007 |
The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Drug Interactions; Enzyme Inhibitors; ErbB Receptors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neuregulin-1; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinazolines; Rats; Receptor, ErbB-4; RNA Interference; RNA, Small Interfering; Synapses; Synaptic Transmission; Transfection; Tyrphostins | 2007 |
Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amines; Animals; Antidepressive Agents; Corpus Striatum; Drug Interactions; Excitatory Amino Acid Agents; Fluoxetine; Gene Expression; Hippocampus; Male; Morpholines; N-Methylaspartate; Potassium; Rats; Rats, Sprague-Dawley; Reboxetine; Receptors, Glutamate; Synaptosomes; Time Factors; Tritium | 2007 |
Rotenone potentiates NMDA currents in substantia nigra dopamine neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Rotenone; Strophanthidin; Substantia Nigra; Uncoupling Agents | 2007 |
Functional interactions between presynaptic NMDA receptors and metabotropic glutamate receptors co-expressed on rat and human noradrenergic terminals.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chromones; Female; Glycine; Hippocampus; Humans; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Resorcinols; Synaptosomes; Tritium | 2007 |
The role of defensins in the excitability of the peripheral vestibular system in the frog: evidence for the presence of communication between the immune and nervous systems.
Topics: Acetylcholine; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Defensins; Animals; Atropine; Cholinergic Antagonists; Cycloleucine; Defensins; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Immune System; In Vitro Techniques; Inflammation; Kainic Acid; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuroimmunomodulation; Neurons, Afferent; Rabbits; Rana temporaria; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Opioid; Semicircular Canals; Synaptic Transmission; Vestibule, Labyrinth | 2007 |
Long-term modifications in the strength of excitatory associative inputs in the piriform cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; Mice; Mice, Inbred C57BL; Models, Biological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Smell; Synapses; Synaptic Transmission; Time Factors | 2007 |
Experience-dependent modification of primary sensory synapses in the mammalian olfactory bulb.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Caspase 3; Cell Count; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Olfactory Bulb; Olfactory Receptor Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory Deprivation; Synapses | 2007 |
A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caspase 3; Cell Death; Cell Survival; Chondroitin Sulfates; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Polyelectrolytes; Polymers; Pregnancy; Rats; Rats, Sprague-Dawley; Tyrosine | 2008 |
Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Female; Hypoxia, Brain; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurotoxins | 2007 |
Cellular and network contributions to excitability of layer 5 neocortical pyramidal neurons in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neocortex; Neurons; Rats; Rats, Wistar | 2007 |
Novel AMPA and kainate receptor antagonists containing the pyrazolo[1,5-c]quinazoline ring system: Synthesis and structure-activity relationships.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Molecular Structure; N-Methylaspartate; Pyrazoles; Quinazolines; Receptors, Kainic Acid; Structure-Activity Relationship | 2008 |
Retinocollicular synapse maturation and plasticity are regulated by correlated retinal waves.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Quinoxalines; Receptors, Nicotinic; Retina; Superior Colliculi; Synapses; Synaptic Transmission; Visual Pathways | 2008 |
Presynaptic modulation by somatostatin in the neostriatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Somatostatin; Valine | 2008 |
GABA regulates excitatory synapse formation in the neocortex via NMDA receptor activation.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bumetanide; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Neocortex; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Synapses | 2008 |
Biochemical, behavioural and electrophysiological investigations of brain maturation in chickens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chickens; Electrophysiology; Humans; Mice; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses | 2008 |
[Electrophysiological characteristics of depressive conditions with passive strategy of the adaptive behavior in rats].
Topics: Adaptation, Physiological; Adaptation, Psychological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Immersion; Male; Maze Learning; N-Methylaspartate; Olfactory Pathways; Rats; Swimming | 2008 |
NMDA and GABA B receptors are involved in controlling nematocyst discharge in hydra.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Drug; Epinephrine; Glutamic Acid; Glycine; Hydra; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Receptors, GABA-B; Serotonin | 2008 |
Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Male; N-Methylaspartate; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Phosphorylation; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tibia; Time Factors | 2008 |
Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1).
Topics: Actin Depolymerizing Factors; Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biophysics; Cells, Cultured; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Mice; Mice, Knockout; N-Methylaspartate; Neurons; p21-Activated Kinases; Patch-Clamp Techniques; Quinoxalines; Synapses | 2009 |
The neuronal basis of attention: rate versus synchronization modulation.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Attention; Bias; Cortical Synchronization; Excitatory Amino Acid Agonists; Haplorhini; Inhibition, Psychological; Models, Neurological; N-Methylaspartate; Neurons; Photic Stimulation; Spectrum Analysis; Time Factors; Visual Cortex; Visual Fields; Visual Pathways; Visual Perception | 2008 |
An attractor hypothesis of obsessive-compulsive disorder.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Nerve Net; Neurons; Obsessive-Compulsive Disorder; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2008 |
Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Addictive; Behavior, Animal; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Exploratory Behavior; In Vitro Techniques; Locomotion; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2008 |
Serotoninergic modulation of sensory transmission to brainstem reticulospinal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lampreys; N-Methylaspartate; Neural Pathways; Receptors, Glutamate; Reticular Formation; Serotonin; Spinal Cord; Synaptic Transmission; Trigeminal Nerve | 2008 |
Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinergic Antagonists; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glutamic Acid; Homovanillic Acid; Injections, Intraventricular; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Scopolamine | 2008 |
Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cycloheximide; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D5; Time Factors; Ventral Tegmental Area | 2008 |
Lack of NMDA-AMPA interaction in antidepressant-like effect of CGP 37849, an antagonist of NMDA receptor, in the forced swim test.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Depressive Disorder; Excitatory Amino Acid Antagonists; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Swimming | 2008 |
Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; In Vitro Techniques; Lysophosphatidylcholines; Lysophospholipids; Mice; Multienzyme Complexes; N-Methylaspartate; Phosphodiesterase I; Phospholipases A2; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrophosphatases; Receptors, Lysophosphatidic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Signal Transduction; Spinal Cord; Substance P | 2008 |
N-Methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involved in the induction of sedative effects under an acute stress in neonatal chicks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chickens; Excitatory Amino Acid Agonists; Glutamic Acid; Immobility Response, Tonic; Kainic Acid; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 2009 |
Chronic intermittent hypoxia impairs heart rate responses to AMPA and NMDA and induces loss of glutamate receptor neurons in nucleus ambiguous of F344 rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Blood Pressure; Brain Stem; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Heart; Heart Rate; Hypoxia; Microinjections; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2009 |
Effects of exogenous excitatory amino acid neurotransmitters on blood-brain barrier disruption in focal cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain Ischemia; Cerebral Cortex; Infarction, Middle Cerebral Artery; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2009 |
Neurotropic effect of exogenous L-carnosine in cultured slices of the olfactory cortex from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carnosine; Dose-Response Relationship, Drug; Long-Term Potentiation; N-Methylaspartate; Nerve Growth Factors; Olfactory Pathways; Rats; Receptors, GABA-B; Tissue Culture Techniques | 2008 |
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Behavior, Animal; Cues; Endocytosis; Excitatory Amino Acid Agonists; Extinction, Psychological; Gene Expression Regulation; Heroin; Heroin Dependence; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Narcotics; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Peptides; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Sucrose; Tandem Mass Spectrometry | 2008 |
GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Brain; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Picrotoxin; Receptors, AMPA; Receptors, GABA-A; Respiration | 2009 |
Electrophysiological characteristics of depressive states in rats with passive strategies of adaptive behavior.
Topics: Adaptation, Physiological; Adaptation, Psychological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Immersion; Male; Maze Learning; N-Methylaspartate; Olfactory Pathways; Rats; Swimming | 2009 |
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors | 2009 |
Optimality and robustness of a biophysical decision-making model under norepinephrine modulation.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biophysical Phenomena; Decision Making; Excitatory Amino Acid Agonists; Humans; Locus Coeruleus; Models, Neurological; N-Methylaspartate; Nerve Net; Neural Networks, Computer; Neurons; Nonlinear Dynamics; Norepinephrine; Reward | 2009 |
Protein SUMOylation modulates calcium influx and glutamate release from presynaptic terminals.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Central Nervous System Stimulants; Endopeptidases; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Wistar; Recombinant Proteins; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; Synaptic Transmission; Synaptosomes | 2009 |
Anterior thalamic lesions stop synaptic plasticity in retrosplenial cortex slices: expanding the pathology of diencephalic amnesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amnesia; Animals; Anterior Thalamic Nuclei; gamma-Aminobutyric Acid; Gyrus Cinguli; Male; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2009 |
Enhanced synaptic long-term potentiation in the anterior cingulate cortex of adult wild mice as compared with that in laboratory mice.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Gyrus Cinguli; Long-Term Potentiation; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2009 |
Topiramate antagonizes NMDA- and AMPA-induced seizure-like activity in planarians.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; N-Methylaspartate; Neuroprotective Agents; Planarians; Quinoxalines; Seizures; Topiramate | 2009 |
Silent synapses onto interneurons in the rat CA1 stratum radiatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Synapses | 2009 |
Differences in biophysical properties of nucleus accumbens medium spiny neurons emerging from inactivation of inward rectifying potassium currents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aplysia; Biophysical Phenomena; Biophysics; Computer Simulation; Electric Stimulation; Excitatory Amino Acid Agonists; Ion Channel Gating; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Nucleus Accumbens; Potassium Channels, Inwardly Rectifying; Reaction Time; Synapses | 2009 |
Subunit-selective palmitoylation regulates the intracellular trafficking of AMPA receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cell Line, Transformed; Cells, Cultured; Endoplasmic Reticulum; Golgi Apparatus; Humans; Lipoylation; Lysosomes; Microtubules; N-Methylaspartate; Neurons; Protein Stability; Rats; Rats, Wistar; Receptors, AMPA; RNA, Messenger; Sodium Channel Blockers; Tetrodotoxin | 2009 |
Moderate hypobaric hypoxia modifies Ca2+-mediated glutamatergic signal transduction in rat cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Excitatory Amino Acid Agonists; Glutamic Acid; Hypoxia; Male; N-Methylaspartate; Rats; Rats, Wistar; Signal Transduction | 2009 |
Regulated expression of surface AMPA receptors reduces excitotoxicity in auditory neurons.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Auditory Threshold; Brain Stem; Cell Death; Cell Membrane; Cells, Cultured; Cochlea; Exocytosis; Mice; Mice, Inbred CBA; N-Methylaspartate; Neurotoxins; Random Allocation; Receptors, AMPA; Receptors, Glutamate; Sensory Receptor Cells; Spiral Ganglion | 2009 |
Non-fibrillar amyloid-beta peptide reduces NMDA-induced neurotoxicity, but not AMPA-induced neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyloid beta-Peptides; Animals; Hippocampus; Mice; Mice, Inbred ICR; Microscopy, Atomic Force; N-Methylaspartate; Neurons; Peptide Fragments; Receptors, N-Methyl-D-Aspartate | 2009 |
Glutamate responsiveness of medial vestibular nucleus neurons in aged rats.
Topics: Action Potentials; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; In Vitro Techniques; Male; Microelectrodes; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vestibular Nuclei | 2010 |
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone | 2009 |
The analgesic action of topical diclofenac may be mediated through peripheral NMDA receptor antagonism.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Biophysics; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Injections, Intramuscular; Isoquinolines; Male; Musculoskeletal Diseases; N-Methylaspartate; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Time Factors | 2009 |
Alterations of excitatory transmission in the lateral amygdala during expression and extinction of fear memory.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Behavior, Animal; Cycloserine; Electric Stimulation; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; In Vitro Techniques; Male; Membrane Potentials; Memory; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission | 2010 |
An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acids; Astrocytes; Cannabinoid Receptor Modulators; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Endocannabinoids; Excitatory Amino Acid Transporter 2; Female; Furans; Mice; Mice, Inbred Strains; Mice, Knockout; Multiple Sclerosis; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Polyunsaturated Alkamides; PPAR gamma; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2010 |
Dysmyelinated axons in shiverer mice are highly vulnerable to alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated toxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Brain; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Hereditary Central Nervous System Demyelinating Diseases; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Movement Disorders; Myelin Basic Protein; N-Methylaspartate; Nerve Degeneration; Nerve Fibers, Myelinated; Neurotoxins; Receptors, AMPA | 2010 |
Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acids; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats | 2010 |
Early synapse formation in developing interneurons of the adult olfactory bulb.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Biophysics; Carrier Proteins; Cell Differentiation; Dendrites; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; N-Methylaspartate; Neurogenesis; Olfactory Bulb; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, GABA-A; Synapses | 2009 |
Neuregulin beta1 enhances peak glutamate-induced intracellular calcium levels through endoplasmic reticulum calcium release in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Calcium; Calcium Signaling; Cells, Cultured; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Inositol 1,4,5-Trisphosphate Receptors; N-Methylaspartate; Neuregulin-1; Neurons; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Ryanodine; Ryanodine Receptor Calcium Release Channel; Second Messenger Systems | 2009 |
Neurodevelopmental effects of chronic exposure to elevated levels of pro-inflammatory cytokines in a developing visual system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Convulsants; Cytokines; Dendrites; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Antagonists; Interleukin-1beta; Interleukin-6; Larva; N-Methylaspartate; Nervous System; Neural Pathways; Neurons; Pentylenetetrazole; Retina; Seizures; Superior Colliculi; Synapses; Synaptic Transmission; Tectum Mesencephali; Time Factors; Tumor Necrosis Factor-alpha; Visual Pathways | 2010 |
Dopamine modulation of excitatory currents in the striatum is dictated by the expression of D1 or D2 receptors and modified by endocannabinoids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cannabinoid Receptor Modulators; Cells, Cultured; Corpus Striatum; Dopamine; Endocannabinoids; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction; Synapses | 2010 |
NMDA and AMPA receptors contribute to the maintenance of substance P-induced thermal hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; N-Methylaspartate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance P | 2010 |
Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Cytoplasm; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Transfection | 2010 |
Bidirectional synaptic plasticity in response to single or paired pulse activation of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Immunolocalization of multiple membrane proteins on a carbon replica with STEM and EDX.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon; Cell Membrane; Freeze Fracturing; Gold Colloid; Hippocampus; Immunohistochemistry; Membrane Proteins; Microscopy, Electron, Scanning; N-Methylaspartate; Nanoparticles; Rats; Receptors, Glutamate; Spectrometry, X-Ray Emission | 2010 |
The involvement of PACAP/VIP system in the synaptic transmission in the hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Learning; Memory; Mice; N-Methylaspartate; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, N-Methyl-D-Aspartate; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Vasoactive Intestinal Peptide; Signal Transduction; Synaptic Transmission; Vasoactive Intestinal Peptide | 2010 |
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Auditory Pathways; Calcium; Calcium Signaling; Cochlear Nucleus; Glutamic Acid; Inferior Colliculi; Models, Animal; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Wistar; Receptors, Glutamate | 2010 |
Altered sensitivity to excitotoxic cell death and glutamate receptor expression between two commonly studied mouse strains.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dose-Response Relationship, Drug; Drug Resistance; Excitatory Amino Acid Agonists; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Pyrimidinones; Receptors, Glutamate; Species Specificity | 2010 |
Frequency switching in a two-compartmental model of the dopaminergic neuron.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Dopamine; Electric Stimulation; Mesencephalon; Models, Neurological; N-Methylaspartate; Neurons; Potassium Channels; Synapses | 2011 |
Dopaminergic D2 receptors activate PKA to inhibit spinal pelvic-urethra reflex in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic AMP-Dependent Protein Kinases; Dopamine D2 Receptor Antagonists; Electromyography; Excitatory Amino Acid Agonists; Female; Models, Animal; N-Methylaspartate; Pelvis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reflex; Urethra | 2010 |
Choice, difficulty, and confidence in the brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Choice Behavior; Decision Making; Electrophysiological Phenomena; gamma-Aminobutyric Acid; Hot Temperature; Humans; Magnetic Resonance Imaging; Models, Neurological; N-Methylaspartate; Neural Networks, Computer; Oxygen; Prefrontal Cortex; Psychomotor Performance; Reaction Time; Reward; Smell; Synapses | 2010 |
Ca2+/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA1 Region, Hippocampal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glucose; Humans; Long-Term Potentiation; Male; N-Methylaspartate; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2011 |
A mathematical model for Cantor coding in the hippocampus.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA1 Region, Hippocampal; Discriminant Analysis; Excitatory Amino Acid Agonists; Mathematical Computing; Models, Neurological; N-Methylaspartate; Nerve Net; Neural Pathways; Pyramidal Cells; Synapses; Time Factors | 2011 |
Curcumin protects against NMDA-induced toxicity: a possible role for NR2A subunit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Calcium; Cells, Cultured; Curcumin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Time Factors | 2011 |
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Membrane Potentials; Microscopy, Confocal; N-Methylaspartate; Nedd4 Ubiquitin Protein Ligases; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA Interference; Transfection; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, Reporter; Glutamic Acid; Luciferases; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; NFATC Transcription Factors; Nifedipine; Potassium; Progesterone; Rats; Rats, Sprague-Dawley | 2011 |
Effect of Mimosa pudica (Linn.) extract on anxiety behaviour and GABAergic regulation of 5-HT neuronal activity in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anxiety; Diazepam; GABA Modulators; Isoxazoles; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mimosa; N-Methylaspartate; Phytotherapy; Plant Extracts; Raphe Nuclei; Receptors, GABA-A; Serotonin | 2012 |
Repeated brief episodes of hypoxia modulate the calcium responses of ionotropic glutamate receptors in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Hypoxia; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Intracellular Fluid; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Ionotropic Glutamate; Time Factors | 2011 |
Blockade of the NMDA and AMPA/kainate receptors in the dorsal raphe nucleus prevents the 5-HT₃ receptor agonist m-chlorophenylbiguanide-induced suppression of REM sleep in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Sleep; Sleep Deprivation; Sleep, REM | 2011 |
Effect of brain-derived neurotrophic factor on activity-regulated cytoskeleton-associated protein gene expression in primary frontal cortical neurons. Comparison with NMDA and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Female; Frontal Lobe; Gene Expression Regulation; Humans; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Time | 2011 |
Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway.
Topics: Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Astrocytes; Biotinylation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Immunoprecipitation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; SNARE Proteins; Somatosensory Cortex; src-Family Kinases; Tyrosine; Valine | 2011 |
Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; CA1 Region, Hippocampal; Dendritic Spines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Long-Term Synaptic Depression; Mice; Mice, Transgenic; Microscopy, Confocal; N-Methylaspartate; Neurons; Organ Culture Techniques; Receptors, Glutamate; Serine; Symporters; Synapses | 2011 |
Behavioural and neuronal activation after microinjections of AMPA and NMDA into the perifornical lateral hypothalamus in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Excitatory Amino Acid Agonists; Exploratory Behavior; Feeding Behavior; Genes, fos; Grooming; Head Movements; Hypothalamic Area, Lateral; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Motor Activity; N-Methylaspartate; Neurons; Neuropeptides; Orexins; Rats; Rats, Wistar | 2011 |
Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence.
Topics: Alcoholism; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Genetic Variation; Humans; Membrane Proteins; N-Methylaspartate; Polymorphism, Single Nucleotide; Protein Transport; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2012 |
Stimulus-dependent state transition between synchronized oscillation and randomly repetitive burst in a model cerebellar granular layer.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellar Cortex; Computer Simulation; Dendrites; gamma-Aminobutyric Acid; Interneurons; Magnesium; Models, Neurological; N-Methylaspartate; Neurons; Rats; Rest | 2011 |
Hippocampal AMPA autoreceptors positively coupled to NMDA autoreceptors traffic in a constitutive manner and undergo adaptative changes following enriched environment training.
Topics: Adaptation, Physiological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzothiadiazines; Carrier Proteins; Cytoskeletal Proteins; D-Aspartic Acid; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Environment; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Guanylate Kinases; Hippocampus; Immunoprecipitation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; N-Ethylmaleimide-Sensitive Proteins; N-Methylaspartate; Nuclear Proteins; Presynaptic Terminals; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptophysin; Synaptosomes; Tritium | 2011 |
Increased expression of dysbindin-1A leads to a selective deficit in NMDA receptor signaling in the hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bacterial Proteins; Biophysics; Carrier Proteins; Cells, Cultured; Clathrin; Dysbindin; Dystrophin-Associated Proteins; Electric Stimulation; Embryo, Mammalian; Endocytosis; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; Long-Term Potentiation; Luminescent Proteins; Male; Mice; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin; Transfection | 2011 |
Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero.
Topics: Abnormalities, Drug-Induced; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; Male; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Time Factors; Valproic Acid | 2011 |
[Selection of proper antiepileptic drugs].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anticonvulsants; Drug Therapy, Combination; Epilepsy; GABA Antagonists; Humans; N-Methylaspartate; Precision Medicine; Sodium Channel Blockers | 2010 |
Functional expression of ionotropic glutamate receptors in the rabbit retinal ganglion cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; N-Methylaspartate; Organ Culture Techniques; Rabbits; Receptors, AMPA; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Synaptic Transmission | 2012 |
Purinergic modulation of the excitatory synaptic input onto rat striatal neurons.
Topics: Adenosine; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Synaptic Transmission | 2012 |
Dopamine-glutamate interplay in the ventral striatum modulates spatial learning in a receptor subtype-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Habituation, Psychophysiologic; Learning; Male; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine; Space Perception; Sulpiride | 2012 |
What a nostril knows: olfactory nerve-evoked AMPA responses increase while NMDA responses decrease at 24-h post-training for lateralized odor preference memory in neonate rat.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Biophysics; Conditioning, Psychological; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Functional Laterality; In Vitro Techniques; Learning; Male; N-Methylaspartate; Nose; Odorants; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Quinoxalines; Rats; Rats, Sprague-Dawley; Smell; Tetrodotoxin | 2012 |
On the mechanisms underlying the depolarization block in the spiking dynamics of CA1 pyramidal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysical Phenomena; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Agonists; Hippocampus; In Vitro Techniques; Models, Neurological; N-Methylaspartate; Nonlinear Dynamics; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses | 2012 |
GluA and GluN receptors regulate the surface density of GluN receptor subunits in cultured neocortical interneurons.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotinylation; Calcium Signaling; Cells, Cultured; Down-Regulation; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Immunohistochemistry; Interneurons; N-Methylaspartate; Neocortex; Nerve Net; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2012 |
Functional role of astrocyte glutamate receptors and carbon monoxide in cerebral vasodilation response to glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Arterioles; Astrocytes; Carbon Monoxide; Cells, Cultured; Cerebrovascular Circulation; Female; Glutamates; Heme Oxygenase (Decyclizing); In Vitro Techniques; Kainic Acid; Male; Models, Animal; N-Methylaspartate; Receptors, Glutamate; Swine; Vasodilation | 2012 |
In vitro studies of the influence of glutamatergic agonists on the Na+,K(+)-ATPase and K(+)-p-nitrophenylphosphatase activities in the hippocampus and frontal cortex of rats.
Topics: 4-Nitrophenylphosphatase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Frontal Lobe; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synaptic Transmission | 2012 |
Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Neuropeptides; Orexins; Rats; Rats, Sprague-Dawley | 2012 |
Location-dependent effects of inhibition on local spiking in pyramidal neuron dendrites.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Signaling; Computational Biology; Computer Simulation; Dendrites; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Models, Neurological; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Wistar; Somatosensory Cortex | 2012 |
Neural differentiation of mouse embryonic stem cells as a tool to assess developmental neurotoxicity in vitro.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chlorpyrifos; Disks Large Homolog 4 Protein; Dopamine; Embryonic Stem Cells; Flow Cytometry; Glial Fibrillary Acidic Protein; Guanylate Kinases; Membrane Proteins; Methylmercury Compounds; Mice; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Oligodendroglia; Organometallic Compounds; Sodium Glutamate; Time Factors; Tubulin; Tyrosine 3-Monooxygenase | 2012 |
Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anxiety; Avoidance Learning; Cadherins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Cells, Cultured; Conditioning, Psychological; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Exploratory Behavior; Eye Proteins; Fear; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Male; Maze Learning; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Microtubule-Associated Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurogenesis; Neurons; Receptors, AMPA; RNA, Messenger; Silver Staining; Statistics, Nonparametric; Synapses; Synaptosomes; Transfection; Vesicle-Associated Membrane Protein 2 | 2012 |
Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2012 |
Glutamatergic input to the lateral hypothalamus stimulates ethanol intake: role of orexin and melanin-concentrating hormone.
Topics: Alcohol Drinking; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; Hypothalamic Area, Lateral; Hypothalamic Hormones; Intracellular Signaling Peptides and Proteins; Male; Melanins; N-Methylaspartate; Neuropeptides; Orexins; Pituitary Hormones; Rats; Rats, Sprague-Dawley | 2013 |
Location-dependent excitatory synaptic interactions in pyramidal neuron dendrites.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Postsynaptic Potentials; Models, Neurological; N-Methylaspartate; Neural Conduction; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Synapses | 2012 |
Burst firing in gonadotrophin-releasing hormone neurones does not require ionotrophic GABA or glutamate receptor activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Male; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Organ Culture Techniques; Receptors, GABA-A; Receptors, Ionotropic Glutamate; Synaptic Potentials; Synaptic Transmission | 2012 |
[Inhibitory regulation of glutamate receptors in the frog motoneuron].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Excitatory Amino Acids; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Microelectrodes; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Poisons; Pyridazines; Rana ridibunda; Receptors, Ionotropic Glutamate; Spinal Cord; Strychnine | 2012 |
Muscarinic control of AMPA receptor responsiveness in mouse spinal cord motoneurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Indoles; Mice; Mice, Inbred C57BL; Motor Neurons; Muscarinic Agonists; N-Methylaspartate; Quinoxalines; Receptors, AMPA; Receptors, Muscarinic; Spinal Cord | 2012 |
A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Cell Adhesion Molecules, Neuronal; Cell Line, Transformed; Dendritic Spines; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Long-Term Potentiation; Membrane Proteins; MicroRNAs; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Structure, Tertiary; Quinoxalines; Rats; RNA Interference; Statistics, Nonparametric; Stereotaxic Techniques; Transduction, Genetic; Transfection | 2012 |
Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Central Nervous System Depressants; Choice Behavior; Conditioning, Operant; Corpus Striatum; Dopamine Antagonists; Electric Stimulation; Ethanol; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Food Preferences; GABA Antagonists; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Sucrose; Sulpiride; Sweetening Agents; Synaptosomes; Up-Regulation | 2012 |
NGL-2 regulates input-specific synapse development in CA1 pyramidal neurons.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Axons; CA1 Region, Hippocampal; Cell Line, Transformed; Cells, Cultured; Electric Stimulation; Electroporation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; In Vitro Techniques; Lentivirus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Netrin-1; Organic Chemicals; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Long-Evans; Receptors, Cell Surface; RNA, Small Interfering; Synapses; Transfection; Tumor Suppressor Proteins | 2012 |
Deficits in morphofunctional maturation of hippocampal mossy fiber synapses in a mouse model of intellectual disability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Outbred Strains; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GluK2 Kainate Receptor; Intellectual Disability; Mice; Mice, Knockout; Mossy Fibers, Hippocampal; N-Methylaspartate; Presynaptic Terminals; Receptors, Kainic Acid; Synapses | 2012 |
Silent synapses persist into adulthood in layer 2/3 pyramidal neurons of visual cortex in dark-reared mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Darkness; Excitatory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Photic Stimulation; Pyramidal Cells; Synapses; Visual Cortex | 2013 |
Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA1 Region, Hippocampal; Cell Line; Encephalomyelitis, Autoimmune, Experimental; Female; GABAergic Neurons; Interleukin-1beta; Long-Term Potentiation; Mice; Multiple Sclerosis; N-Methylaspartate; Synapses; Synaptic Transmission | 2013 |
Inhibitory effects of acorn extract on glutamate-induced calcium signaling in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Signaling; Cells, Cultured; Glutamic Acid; Hippocampus; N-Methylaspartate; Plant Extracts; Quercus; Rats; Rats, Sprague-Dawley | 2013 |
Synaptic potentiation in the nociceptive amygdala following fear learning in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Conditioning, Psychological; Excitatory Postsynaptic Potentials; Fear; Kinetics; Learning; Long-Term Potentiation; Mice; N-Methylaspartate; Nociception; Receptors, N-Methyl-D-Aspartate; Sensory Thresholds; Stress, Mechanical; Synapses; Temperature | 2013 |
Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antipsychotic Agents; Computer Simulation; Drug Discovery; gamma-Aminobutyric Acid; Hippocampus; Humans; Models, Neurological; N-Methylaspartate; Neural Networks, Computer; Schizophrenia; User-Computer Interface | 2013 |
Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Brain; Brain Injuries; Bromodeoxyuridine; Calpain; Cell Death; Dendrites; Disease Models, Animal; Electric Stimulation; Embryo, Mammalian; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Intermediate Filament Proteins; Long-Term Potentiation; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Nestin; Neurons; Patch-Clamp Techniques; Phosphotransferases; Psychomotor Performance; RNA, Messenger; Silver Staining; Transfection; Tyrosine 3-Monooxygenase | 2013 |
Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Humans; In Vitro Techniques; Interleukin-1beta; Ion Channel Gating; Male; Minocycline; N-Methylaspartate; Neuroglia; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Interleukin-1; Receptors, N-Methyl-D-Aspartate; Substantia Gelatinosa; Tetrodotoxin | 2013 |
Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bacterial Proteins; Channelrhodopsins; Clozapine; Cocaine; Compulsive Behavior; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Nerve Net; Neural Pathways; Neurons; Nucleus Accumbens; Receptors, Dopamine D2; Reward; Self Administration; Synapses; Time Factors | 2013 |
Peculiarities of amnesia development during memory reconsolidation impairment induced by isolated or combined treatment with neurotransmitter receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Conditioning, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Helix, Snails; Memory; Models, Animal; N-Methylaspartate; Receptors, Neurotransmitter; Serotonin Antagonists | 2013 |
Defective synaptic transmission and structure in the dentate gyrus and selective fear memory impairment in the Rsk2 mutant mouse model of Coffin-Lowry syndrome.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Coffin-Lowry Syndrome; Conditioning, Psychological; Cues; Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Fear; Freezing Reaction, Cataleptic; In Vitro Techniques; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Mutation; N-Methylaspartate; Nerve Tissue Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Synapses; Synaptic Transmission | 2013 |
A bionics chemical synapse.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Bionics; Computer Simulation; Electric Power Supplies; Electronics, Medical; Enzymes, Immobilized; Equipment Design; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Iontophoresis; Kinetics; Models, Theoretical; N-Methylaspartate; Synapses; Synaptic Transmission | 2013 |
Active processing of spatio-temporal input patterns in silicon dendrites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Artificial Intelligence; Brain; Computer Simulation; Dendrites; Humans; Models, Neurological; Models, Theoretical; N-Methylaspartate; Neural Networks, Computer; Neural Pathways; Neurons; Silicon; Time Factors | 2013 |
Conductance-based refractory density model of primary visual cortex.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Models, Neurological; N-Methylaspartate; Neural Conduction; Neurons; Orientation; Photic Stimulation; Synapses; Visual Cortex; Visual Fields | 2014 |
L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calcium Channels, L-Type; Cells, Cultured; Cognition Disorders; Dentate Gyrus; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Potassium Channels, Voltage-Gated; Synapses; tau Proteins | 2014 |
Effects of the blood components on the AMPA and NMDA synaptic responses in brain slices in the onset of hemorrhagic stroke.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Transfusion, Autologous; Brain; Erythrocytes; Excitatory Postsynaptic Potentials; In Vitro Techniques; Intracranial Hemorrhages; N-Methylaspartate; Olfactory Pathways; Rats; Stroke; Synapses | 2013 |
Time-dependent decreases in nucleus accumbens AMPA/NMDA ratio and incubation of sucrose craving in adolescent and adult rats.
Topics: Administration, Oral; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Weight; Craving; Cues; Dietary Sucrose; Drug-Seeking Behavior; Electric Stimulation; GABAergic Neurons; Male; N-Methylaspartate; Nucleus Accumbens; Patch-Clamp Techniques; Rats, Long-Evans; Reward; Self Administration; Synaptic Transmission; Time Factors; Tissue Culture Techniques; Water | 2014 |
CaMKII activity in the ventral tegmental area gates cocaine-induced synaptic plasticity in the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors; Ventral Tegmental Area | 2014 |
Superoxide anions in paraventricular nucleus modulate adipose afferent reflex and sympathetic activity in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Adipose Tissue, White; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Cyclic N-Oxides; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Spin Labels; Superoxide Dismutase; Superoxides; Sympathetic Nervous System | 2013 |
Glutamate receptors in the nucleus tractus solitarius contribute to ventilatory acclimatization to hypoxia in rat.
Topics: Acclimatization; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chemoreceptor Cells; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia; Male; N-Methylaspartate; Pulmonary Ventilation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus | 2014 |
Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine.
Topics: Acute Disease; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood-Brain Barrier; Brain Ischemia; Cell Membrane Permeability; Cells, Cultured; Chronic Disease; Deoxyadenosines; Disease Models, Animal; Glucose; Male; Mice; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Oxygen; Pilocarpine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Status Epilepticus; Thionucleosides | 2014 |
NMDA receptor activation strengthens weak electrical coupling in mammalian brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Dendritic Spines; Electrical Synapses; Gap Junctions; Ion Transport; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2014 |
NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Dendrites; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neural Pathways; Neurons; Receptors, N-Methyl-D-Aspartate; Thalamus | 2014 |
Different effects of local anesthetics on extracellular signal-regulated kinase phosphorylation in rat dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Capsaicin; Extracellular Signal-Regulated MAP Kinases; Ionomycin; Male; N-Methylaspartate; Phosphorylation; Posterior Horn Cells; Rats | 2014 |
Striatal synaptic dysfunction and hippocampal plasticity deficits in the Hu97/18 mouse model of Huntington disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA1 Region, Hippocampal; Cell Membrane; Disease Models, Animal; Excitatory Postsynaptic Potentials; Hippocampus; Humans; Huntington Disease; Long-Term Potentiation; Mice; Mice, Transgenic; N-Methylaspartate; Neostriatum; Neuronal Plasticity; Neurons; Pyramidal Cells; Synapses | 2014 |
Contrasting forms of cocaine-evoked plasticity control components of relapse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopaminergic Neurons; Drug-Seeking Behavior; Female; Hippocampus; Male; Mice; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Prefrontal Cortex; Receptors, AMPA; Receptors, Dopamine D1; Recurrence; Synapses | 2014 |
Environmental enrichment restores CA1 hippocampal LTP and reduces severity of seizures in epileptic mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Disease Models, Animal; Electric Stimulation; Environment; Epilepsy; Excitatory Amino Acid Agonists; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques | 2014 |
Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cell Differentiation; Cell Line; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophysiology; Gene Expression Regulation; Hippocampus; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Quinoxalines; Receptors, Ionotropic Glutamate | 2014 |
Region- and age-dependent reductions of hippocampal long-term potentiation and NMDA to AMPA ratio in a genetic model of Alzheimer's disease.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Hippocampus; Long-Term Potentiation; Mice, Transgenic; Molecular Targeted Therapy; Mutation; N-Methylaspartate; Neostigmine; Plaque, Amyloid | 2015 |
Efficient, complete deletion of synaptic proteins using CRISPR.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Humans; In Vitro Techniques; Luminescent Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Red Fluorescent Protein; RNA; Synapses; Synaptophysin | 2014 |
Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biocatalysis; Calcium Channels; Cell Membrane; Disks Large Homolog 4 Protein; Female; Glutamic Acid; Guanylate Kinases; HEK293 Cells; Humans; Male; Membrane Proteins; Mice; Models, Biological; N-Methylaspartate; Protein Binding; Racemases and Epimerases; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2014 |
Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; AIDS-Associated Nephropathy; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corpus Striatum; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Morphine; N-Methylaspartate; Primary Cell Culture; Receptors, Opioid, mu; Ryanodine; Sodium; Synapses; tat Gene Products, Human Immunodeficiency Virus | 2014 |
Prenatal nicotine is associated with reduced AMPA and NMDA receptor-mediated rises in calcium within the laterodorsal tegmentum: a pontine nucleus involved in addiction processes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Humans; Mice; Motivation; N-Methylaspartate; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance-Related Disorders; Tegmentum Mesencephali | 2015 |
Glutamatergic transmission is involved in the long lasting sexual inhibition of sexually exhausted male rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Copulation; Dose-Response Relationship, Drug; Ejaculation; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Satiety Response; Sexual Behavior, Animal; Synaptic Transmission; Time Factors | 2015 |
Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enkephalins; Glutamic Acid; Immunohistochemistry; Inhalant Abuse; Long-Term Synaptic Depression; Morpholines; N-Methylaspartate; Neural Inhibition; Neurons; Nucleus Accumbens; Phenotype; Protein Precursors; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; RNA, Messenger; Solvents; Synaptic Transmission; Toluene | 2016 |
Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels, L-Type; Cations; Cell Membrane; Cells, Cultured; Glutamic Acid; Hippocampus; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Maze Learning; N-Methylaspartate; Neurons; Protein Kinase C; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate | 2015 |
Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminoacetonitrile; Animals; Apoptosis; Autistic Disorder; Behavior, Animal; Caspase 3; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Immunohistochemistry; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Phenotype; Phosphorylation; Protein Isoforms | 2015 |
Nitrous oxide directly inhibits action potential-dependent neurotransmission from single presynaptic boutons adhering to rat hippocampal CA3 neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA3 Region, Hippocampal; Electric Stimulation; Female; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; N-Methylaspartate; Nitrous Oxide; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission | 2015 |
Optogenetic stimulation reveals distinct modulatory properties of thalamostriatal vs corticostriatal glutamatergic inputs to fast-spiking interneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Channelrhodopsins; Corpus Striatum; Electric Stimulation; Excitatory Postsynaptic Potentials; Interneurons; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; N-Methylaspartate; Patch-Clamp Techniques; Recombinant Fusion Proteins; Synapses; Thalamus | 2015 |
Cocaine self-administration induces changes in synaptic transmission and plasticity in ventral hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA1 Region, Hippocampal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Male; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Self Administration; Synaptic Transmission | 2017 |
Pathway-Specific Remodeling of Thalamostriatal Synapses in Parkinsonian Mice.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Functional Laterality; Homeodomain Proteins; Medial Forebrain Bundle; Mice; N-Methylaspartate; Neural Pathways; Oxidopamine; Parkinsonian Disorders; Synapses; Thalamus; Transcription Factors; Tyrosine 3-Monooxygenase; Vesicular Glutamate Transport Protein 2 | 2016 |
Short-Term Synaptic Plasticity at Interneuronal Synapses Could Sculpt Rhythmic Motor Patterns.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biophysics; Calcium; Electric Stimulation; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Feedback, Physiological; Functional Laterality; In Vitro Techniques; Interneurons; Lampreys; Locomotion; Models, Neurological; Motor Neurons; N-Methylaspartate; Nerve Net; Neuronal Plasticity; Periodicity; Spinal Cord; Synapses | 2016 |
Differential involvement of glutamatergic and catecholaminergic activity within the amygdala during taste aversion retrieval on memory expression and updating.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Avoidance Learning; Catecholamines; Cobalt; Conditioning, Psychological; Excitatory Amino Acid Agents; Exploratory Behavior; Glutamic Acid; Immobility Response, Tonic; Male; Mental Recall; Microdialysis; N-Methylaspartate; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Swimming; Taste | 2016 |
Interferon-gamma potentiates NMDA receptor signaling in spinal dorsal horn neurons via microglia-neuron interaction.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Communication; Chemokine CCL2; Interferon gamma Receptor; Interferon-gamma; Ion Channel Gating; Male; Microglia; Models, Biological; N-Methylaspartate; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, CCR2; Receptors, Interferon; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2016 |
Low excitatory innervation balances high intrinsic excitability of immature dentate neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Electric Stimulation; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Female; Gene Expression; Integrases; Male; Mice; Mice, Transgenic; Microtomy; N-Methylaspartate; Nestin; Neural Inhibition; Neural Stem Cells; Neurogenesis; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Pyridazines; Synapses; Tamoxifen; Tissue Culture Techniques | 2016 |
FoxP2 directly regulates the reelin receptor VLDLR developmentally and by singing.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Finches; Forkhead Transcription Factors; Gene Expression Regulation, Developmental; Learning; Male; N-Methylaspartate; Neuronal Plasticity; Promoter Regions, Genetic; Protein Binding; Receptors, LDL; Transcriptional Activation; Vocalization, Animal | 2016 |
Nitric oxide modulates blood pressure through NMDA receptors in the rostral ventrolateral medulla of conscious rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arterial Pressure; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2016 |
Spike-Based Bayesian-Hebbian Learning of Temporal Sequences.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bayes Theorem; Computational Biology; Humans; Learning; Models, Neurological; N-Methylaspartate; Neocortex; Neural Networks, Computer; Neuronal Plasticity | 2016 |
AMPA/NMDA cooperativity and integration during a single synaptic event.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2016 |
The Effect of Glutamate Receptor Agonists on Mouse Retinal Astrocyte [Ca(2+)]i.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cycloleucine; Excitatory Amino Acid Agonists; Fura-2; Methoxyhydroxyphenylglycol; Mice, Inbred C57BL; N-Methylaspartate; Receptors, Glutamate; Retina | 2016 |
Potentiation of synaptic transmission in Rat anterior cingulate cortex by chronic itch.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Chronic Disease; Cyclopropanes; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gyrus Cinguli; N-Methylaspartate; Neurons; Pruritus; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission; Up-Regulation | 2016 |
Synaptic plasticity and spatial working memory are impaired in the CD mouse model of Williams-Beuren syndrome.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gene Deletion; Hippocampus; Long-Term Potentiation; Memory, Short-Term; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; Neurons; Presynaptic Terminals; Williams Syndrome | 2016 |
The effect of bilirubin on the excitability of mitral cells in the olfactory bulb of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bilirubin; Liver Diseases; N-Methylaspartate; Neurons; Olfaction Disorders; Olfactory Bulb; Rats; Synaptic Transmission | 2016 |
Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Central Nervous System; Crystallography; Drosophila melanogaster; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Ligands; N-Methylaspartate; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 2016 |
GSK-3: A key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced AMPA to NMDA throughput.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Bipolar Disorder; Glycogen Synthase Kinase 3; Humans; Ketamine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2016 |
β-Catenin in the Adult Visual Cortex Regulates NMDA-Receptor Function and Visual Responses.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; beta Catenin; Electric Stimulation; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Parvalbumins; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sensory Deprivation; Synaptic Potentials; Visual Cortex; White Matter | 2018 |
Reduced responses to glutamate receptor agonists follow loss of astrocytes and astroglial glutamate markers in the nucleus tractus solitarii.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arterial Pressure; Astrocytes; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Heart Rate; Immunotoxins; Male; N-Methylaspartate; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Solitary Nucleus; Synaptic Transmission; Vesicular Glutamate Transport Protein 2 | 2017 |
Sensory Deprivation Triggers Synaptic and Intrinsic Plasticity in the Hippocampus.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Corticosterone; Excitatory Postsynaptic Potentials; Exploratory Behavior; Hippocampus; In Vitro Techniques; Maze Learning; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Net; Neurons; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Sensory Deprivation; Synaptic Transmission; Vibrissae | 2017 |
Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Epigenesis, Genetic; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Male; Methylazoxymethanol Acetate; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2017 |
Neurotoxicity of propofol on rat hypoglossal motoneurons in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis Inducing Factor; Cell Count; gamma-Aminobutyric Acid; Glycine; Hypoglossal Nerve; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Propofol; Rats, Wistar | 2017 |
Callosal injury-induced working memory impairment: a computational network modeling study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Computer Simulation; Corpus Callosum; gamma-Aminobutyric Acid; Humans; Memory Disorders; Memory, Short-Term; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Pyramidal Cells; Reaction Time; Synapses | 2017 |
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclin-Dependent Kinase 5; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; Neurons; Phosphopyruvate Hydratase; Piperidines; Pyridazines; Sensory Deprivation; Visual Cortex; Visual Pathways | 2018 |
Partial inhibition of catecholamine activity and enhanced responsiveness to NMDA after sustained administration of vortioxetine.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Brain; Catecholamines; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Sulfides; Time Factors; Vortioxetine | 2018 |
Prefrontal Cortex Drives Distinct Projection Neurons in the Basolateral Amygdala.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Basolateral Nuclear Complex; Channelrhodopsins; Cholera Toxin; Dependovirus; Excitatory Postsynaptic Potentials; Genetic Vectors; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2017 |
Fast-Spiking Interneurons Supply Feedforward Control of Bursting, Calcium, and Plasticity for Efficient Learning.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Signaling; Interneurons; Learning; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Net; Neuronal Plasticity | 2018 |
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dentate Gyrus; Female; Gabapentin; Male; Mice; Muscimol; N-Methylaspartate; Neural Stem Cells; Neurons; Phenytoin; Receptors, Purinergic P2X7; Tetrodotoxin; Valproic Acid | 2018 |
Modeling Schizophrenia's Abnormal Cortical Neural Synchrony in Monkeys.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Haplorhini; Humans; Ketamine; N-Methylaspartate; Schizophrenia | 2018 |
Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Agents; Dopaminergic Neurons; Glutamic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Patch-Clamp Techniques; Receptors, Dopamine D1; Substance-Related Disorders; Synaptic Transmission; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 2 | 2018 |
Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cues; Dendritic Spines; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; Mice; N-Methylaspartate; Neuronal Plasticity; Neurons; Nucleus Accumbens; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials; Synaptic Transmission | 2020 |
The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Calcium Signaling; Dendrites; Female; Gene Expression Regulation, Developmental; Heterozygote; Hippocampus; Male; Maze Learning; Mice; Miniature Postsynaptic Potentials; N-Methylaspartate; NAV1.2 Voltage-Gated Sodium Channel; Neocortex; Prefrontal Cortex; Protein Engineering; Pyramidal Cells; Social Behavior | 2019 |
Glutamatergic activation of A1 and A2 noradrenergic neurons in the rat brain stem.
Topics: Adrenergic Neurons; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Excitatory Amino Acid Agents; Female; Immunohistochemistry; Kainic Acid; N-Methylaspartate; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Tyrosine 3-Monooxygenase | 2019 |
An efficient analytical reduction of detailed nonlinear neuron models.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; gamma-Aminobutyric Acid; Mice; Models, Neurological; N-Methylaspartate; Neural Networks, Computer; Neurons; Nonlinear Dynamics; Pyramidal Cells; Spatio-Temporal Analysis; Synapses | 2020 |
Interleukin-10 restores glutamate receptor-mediated Ca
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Calcium; Cells, Cultured; Cerebral Cortex; Interleukin-10; Mice; N-Methylaspartate; Receptors, Glutamate; Transcription Factors | 2022 |
Melatonin Suppresses the Kainate Receptor-Mediated Excitation on Gonadotropin-Releasing Hormone Neurons in Female and Male Prepubertal Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Agonists; Female; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Kainic Acid; Male; Melatonin; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Pertussis Toxin; Puberty; Receptors, Kainic Acid | 2020 |
EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Energy Metabolism; Ephrin-B1; Ephrin-B2; Excitatory Amino Acid Agents; Glucose; Homeostasis; Male; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Pro-Opiomelanocortin; Receptors, N-Methyl-D-Aspartate | 2020 |
Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Azepines; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Drug Tolerance; Male; MAP Kinase Signaling System; Mice; Morphine; Morphine Dependence; N-Methylaspartate; Triazoles | 2021 |
Contribution of Ionotropic Glutamatergic Receptors to Excitability and Attentional Signals in Macaque Frontal Eye Field.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Attention; Excitatory Amino Acid Agonists; Frontal Lobe; Macaca mulatta; Male; N-Methylaspartate; Photic Stimulation; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Saccades | 2021 |
A human stem cell-derived test system for agents modifying neuronal N-methyl-D-aspartate-type glutamate receptor Ca
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Neurons; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2021 |
Long-term exposure to high glucose induces changes in the expression of AMPA receptor subunits and glutamate transmission in primary cultured cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cell Death; Cells, Cultured; Cerebral Cortex; Female; Glucose; Glutamic Acid; N-Methylaspartate; Neurons; Protein Subunits; Rats, Wistar; Receptors, AMPA; Synaptophysin; Synaptotagmins; Vesicular Glutamate Transport Protein 1 | 2022 |
Hippocampal AMPA- and NMDA-induced cGMP signals are mainly generated by NO-GC2 and are under tight control by PDEs 1 and 2.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Hippocampus; Mice; N-Methylaspartate; Nitric Oxide; Phosphoric Diester Hydrolases; Protein Isoforms | 2022 |
Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Benzodiazepines; Female; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Mice; N-Methylaspartate; Receptors, GABA; Receptors, GABA-A; Sucrose | 2022 |
Cervical spinal hemisection alters phrenic motor neuron glutamatergic mRNA receptor expression.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cervical Cord; Diaphragm; In Situ Hybridization, Fluorescence; Motor Neurons; N-Methylaspartate; Phrenic Nerve; Rats; Receptors, N-Methyl-D-Aspartate; Recovery of Function; RNA, Messenger; Spinal Cord Injuries | 2022 |
The continually evolving role of NMDA receptors in neurobiology and disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Kainic Acid; N-Methylaspartate; Neurobiology; Receptors, N-Methyl-D-Aspartate | 2022 |
Hyperammonemia Alters the Function of AMPA and NMDA Receptors in Hippocampus: Extracellular cGMP Reverses Some of These Alterations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic GMP; Hippocampus; Hyperammonemia; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2022 |
Layer-specific distribution and expression pattern of AMPA- and NMDA-type glutamate receptors in the barrel field of the adult rat somatosensory cortex: a quantitative electron microscopic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrons; Glutamic Acid; N-Methylaspartate; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses | 2023 |
Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Hyperthyroidism; Long-Term Potentiation; Mice; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2022 |
Calcineurin Controls Hypothalamic NMDA Receptor Activity and Sympathetic Outflow.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Calcineurin; Calcineurin Inhibitors; Hypertension; Hypothalamus; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System; Tacrolimus | 2022 |
The combined effects of corticosterone and brain-derived neurotrophic factor on plasticity-related receptor phosphorylation and expression at the synaptic surface in male Sprague-Dawley rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Hippocampus; Male; N-Methylaspartate; Phosphorylation; Rats; Rats, Sprague-Dawley | 2022 |
Rutin prevents seizures in kainic acid-treated rats: evidence of glutamate levels, inflammation and neuronal loss modulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents; Carbamazepine; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Hippocampus; HMGB1 Protein; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Kainic Acid; N-Methylaspartate; Rats; Receptors, Interleukin-1; Rutin; Seizures; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Granulocyte Colony-Stimulating Factor; Hippocampus; Humans; N-Methylaspartate; Neuroprotective Agents; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, AMPA; Receptors, Glutamate; Risperidone; Saline Solution; Valproic Acid | 2022 |
Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Binding Proteins; Mice; N-Methylaspartate; Neural Cell Adhesion Molecules; Protein Precursors; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2022 |
Astaxanthin Protection against Neuronal Excitotoxicity via Glutamate Receptor Inhibition and Improvement of Mitochondrial Function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antioxidants; Calcium; Glutamic Acid; Humans; Mitochondria; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Reactive Oxygen Species; Receptors, AMPA; Receptors, Glutamate; Xanthophylls | 2022 |
Antibody Properties Associate with Clinical Phenotype in LGI1 Encephalitis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoantibodies; Encephalitis; Intracellular Signaling Peptides and Proteins; Leucine; Limbic Encephalitis; Mice; N-Methylaspartate; Phenotype; Seizures | 2023 |
Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hippocampus; Humans; Infant, Newborn; MicroRNAs; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 2023 |
Two types of GLR channels cooperate differently in light and dark growth of Arabidopsis seedlings.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arabidopsis; Arabidopsis Proteins; Mutation; N-Methylaspartate; Plants; Seedlings | 2023 |
[Glutamate and its ionotropic receptor agonists inhibit the response to acute hypoxia in carotid body of rats].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Carotid Body; Glutamic Acid; Hypoxia; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2023 |
Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Glutamic Acid; N-Methylaspartate; Nucleus Accumbens; Oxycodone; Rats; Rats, Sprague-Dawley; Self Administration | 2024 |