Compounds > alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ly 404187

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with ly 404187 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Bond, A; Huff, K; Lodge, D; Vandergriff, J1
Baumbarger, PJ; Muhlhauser, M; Nisenbaum, ES; Yang, CR; Zhai, J1
McCulloch, J; Milne, S; O'Neill, MJ; Sharkey, J; Voss, OP1
Castner, SA; Holden, DE; Menniti, FS; Roberts, BM; Schmidt, CJ; Seymour, PA; Shaffer, CL; Williams, GV1
Awasaki, Y; Kaku, T; Kimura, H; Kosugi, Y; Kuno, H; Kunugi, A; Sogabe, S; Suzuki, A; Suzuki, M; Suzuki, N; Tajima, Y; Toyofuku, M1

Other Studies

5 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ly 404187

ArticleYear
Potentiation of responses to AMPA on central neurones by LY392098 and LY404187 in vivo.
    Neuropharmacology, 2001, Volume: 40, Issue:8

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Female; Hippocampus; Injections, Intravenous; Male; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spinal Cord; Stereotaxic Techniques; Sulfonamides; Thiophenes

2001
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides

2001
Molecular mechanisms of neurite growth with AMPA receptor potentiation.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Humans; Neurites; Neuroblastoma; Neurofilament Proteins; Receptor, trkA; Receptors, AMPA; Sulfonamides

2007
Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction.
    Behavioural brain research, 2010, Sep-01, Volume: 212, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Area Under Curve; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Ketamine; Macaca fascicularis; Macaca mulatta; Memory Disorders; Memory, Short-Term; Motor Activity; Neuropsychological Tests; Reaction Time; Sulfonamides; Thiophenes; Time Factors

2010
Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement.
    Scientific reports, 2021, 07-15, Volume: 11, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Calcium; CHO Cells; Cognition; Cricetulus; Female; Humans; Macaca fascicularis; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Neurons; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides

2021