alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ketamine

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with ketamine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's11 (44.00)18.2507
2000's5 (20.00)29.6817
2010's6 (24.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Baudry, M; Maren, S; Shors, TJ; Thompson, RF; Tocco, G1
Heinemann, U; Mudrick, LA1
Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE1
Fedele, E; Raiteri, M; Versace, P1
Hu, B; Nissen, R; Renaud, LP1
Headley, PM; Herrero, JF; Parsons, CG1
Dickie, BG; Greenfield, SA; Jones, SA; Klegeris, A1
Lücke, T; Neugebauer, V; Schaible, HG1
Henry, JL; Radhakrishnan, V1
Chizh, BA; Headley, PM1
Glowinski, J; Pirot, S; Thierry, AM1
Sharp, JW1
Shi, WX; Zhang, XX1
Alonso, TJ; Castro Fuentes, R; García Dopico, J; González Hernández, T; Perdomo Díaz, J; Rodríguez Díaz, M1
Chizh, BA; Christoph, T; Englberger, W; Parsons, CG; Schiene, K1
Chen, G; Du, J; Maeng, S; Manji, HK; McCammon, J; Schloesser, RJ; Zarate, CA1
Diazgranados, N; Machado-Vieira, R; Salvadore, G; Zarate, CA1
Castner, SA; Holden, DE; Menniti, FS; Roberts, BM; Schmidt, CJ; Seymour, PA; Shaffer, CL; Williams, GV1
Akinfiresoye, L; Tizabi, Y1
Machado-Vieira, R; Zarate, CA1
Cavalleri, L; Chiamulera, C; Collo, G; Kunath, T; Merlo Pich, E; Millan, MJ; Spano, PF1
Gilbert, JR; Nugent, AC; Wills, KE; Yarrington, JS; Zarate, CA1
Brooks, G; Hasekiu, E; Ingle Gonzalez, JE; Kusi, M; Noakes, J1
Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P1
Hara, H; Kimura, H; Suzuki, A1

Reviews

2 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ketamine

ArticleYear
Ketamine and the next generation of antidepressants with a rapid onset of action.
    Pharmacology & therapeutics, 2009, Volume: 123, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Antagonists; Humans; Ketamine; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors

2009
Role of the AMPA receptor in antidepressant effects of ketamine and potential of AMPA receptor potentiators as a novel antidepressant.
    Neuropharmacology, 2023, 01-01, Volume: 222

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Humans; Ketamine; Receptors, AMPA; Seizures

2023

Trials

1 trial(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ketamine

ArticleYear
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling.
    The international journal of neuropsychopharmacology, 2018, 08-01, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Affect; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infusions, Intravenous; Ketamine; Magnetoencephalography; Male; Middle Aged; Models, Neurological; N-Methylaspartate; Time Factors; Treatment Outcome; Young Adult

2018

Other Studies

22 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ketamine

ArticleYear
Long-term potentiation is associated with increased [3H]AMPA binding in rat hippocampus.
    Brain research, 1992, Feb-28, Volume: 573, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Autoradiography; Electric Stimulation; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Male; Multivariate Analysis; Phencyclidine; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Synapses; Tritium

1992
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
    Neuroscience letters, 1990, Aug-14, Volume: 116, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium

1990
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
    Science (New York, N.Y.), 1988, Aug-05, Volume: 241, Issue:4866

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord

1988
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
    European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley

1993
N-methyl-D-aspartate receptor antagonist ketamine selectively attenuates spontaneous phasic activity of supraoptic vasopressin neurons in vivo.
    Neuroscience, 1994, Volume: 59, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Injections, Intravenous; Ketamine; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Vasopressins

1994
Memantine selectively depresses NMDA receptor-mediated responses of ratspinal neurones in vivo.
    Neuroscience letters, 1994, Jan-03, Volume: 165, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dose-Response Relationship, Drug; Injections, Intravenous; Iontophoresis; Kainic Acid; Ketamine; Male; Memantine; Neurons; Nociceptors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1994
The subthalamo-nigral pathway regulates movement and concomitant acetylcholinesterase release from the substantia nigra.
    Journal of neural transmission. General section, 1994, Volume: 98, Issue:1

    Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Guinea Pigs; Ketamine; Male; Motor Activity; N-Methylaspartate; Neural Pathways; Substantia Nigra; Urethane

1994
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input.
    Neuroscience letters, 1993, May-28, Volume: 155, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Ketamine; Male; Neurons; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1993
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
    Neuroscience, 1993, Volume: 55, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses

1993
Thyrotropin-releasing hormone facilitates spinal nociceptive responses by potentiating NMDA receptor-mediated transmission.
    European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Hot Temperature; Ketamine; Male; N-Methylaspartate; Pain Measurement; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Thyrotropin-Releasing Hormone

1996
Excitatory responses evoked in prefrontal cortex by mediodorsal thalamic nucleus stimulation: influence of anaesthesia.
    European journal of pharmacology, 1995, Oct-04, Volume: 285, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Anesthetics; Animals; Halothane; Ketamine; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thalamus

1995
PCP and ketamine inhibit non-NMDA glutamate receptor mediated hsp70 induction.
    Brain research, 1996, Jul-29, Volume: 728, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Female; Hippocampus; HSP70 Heat-Shock Proteins; Ketamine; Phencyclidine; Rats; Rats, Sprague-Dawley

1996
Dendritic glutamate-induced bursting in the prefrontal cortex: further characterization and effects of phencyclidine.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Hallucinogens; Ketamine; Lysine; Male; Membrane Potentials; N-Methylaspartate; Phencyclidine; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses

2003
Extracellular taurine in the substantia nigra: taurine-glutamate interaction.
    Journal of neuroscience research, 2004, May-15, Volume: 76, Issue:4

    Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Chemistry; Calcium; Chelating Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Antagonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Ketamine; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Substantia Nigra; Taurine; Time Factors; Zinc

2004
The antiallodynic effect of NMDA antagonists in neuropathic pain outlasts the duration of the in vivo NMDA antagonism.
    Neuropharmacology, 2006, Volume: 51, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cold Temperature; Constriction, Pathologic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fentanyl; Iontophoresis; Ketamine; Male; Motor Activity; N-Methylaspartate; Pain; Peripheral Nervous System Diseases; Phthalazines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

2006
Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
    Biological psychiatry, 2008, Feb-15, Volume: 63, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Helplessness, Learned; Hippocampus; Ketamine; Male; Mice; Phosphorylation; Psychomotor Performance; Receptors, AMPA; Swimming; Time Factors

2008
Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction.
    Behavioural brain research, 2010, Sep-01, Volume: 212, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Area Under Curve; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Ketamine; Macaca fascicularis; Macaca mulatta; Memory Disorders; Memory, Short-Term; Motor Activity; Neuropsychological Tests; Reaction Time; Sulfonamides; Thiophenes; Time Factors

2010
Antidepressant effects of AMPA and ketamine combination: role of hippocampal BDNF, synapsin, and mTOR.
    Psychopharmacology, 2013, Volume: 230, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Hippocampus; Ketamine; Male; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Swimming; Synapsins; TOR Serine-Threonine Kinases

2013
GSK-3: A key regulatory target for ketamine's rapid antidepressant effects mediated by enhanced AMPA to NMDA throughput.
    Bipolar disorders, 2016, Volume: 18, Issue:8

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Bipolar Disorder; Glycogen Synthase Kinase 3; Humans; Ketamine; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

2016
Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling.
    Molecular psychiatry, 2018, Volume: 23, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Dopaminergic Neurons; Hippocampus; Humans; Induced Pluripotent Stem Cells; Ketamine; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Receptors, AMPA; Receptors, Dopamine D3; Receptors, Glutamate; Signal Transduction; TOR Serine-Threonine Kinases

2018
Modeling Schizophrenia's Abnormal Cortical Neural Synchrony in Monkeys.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 08-22, Volume: 38, Issue:34

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Haplorhini; Humans; Ketamine; N-Methylaspartate; Schizophrenia

2018
Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice.
    Biological psychiatry, 2022, 08-01, Volume: 92, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Benzodiazepines; Female; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Mice; N-Methylaspartate; Receptors, GABA; Receptors, GABA-A; Sucrose

2022