alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with ibotenic acid in 431 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 80 (18.56) | 18.7374 |
| 1990's | 349 (80.97) | 18.2507 |
| 2000's | 2 (0.46) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brehm, L; Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Hall, RA; Kessler, M; Lynch, G | 1 |
| Greene, RW; McCarley, RW; Stevens, DR | 1 |
| Cox, JA; Seeburg, PH; Stein, E; Verdoorn, TA | 1 |
| Cerne, R; Randic, M | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Kemel, ML | 1 |
| Hong, JS; McMillian, M; Pennypacker, KR | 1 |
| Bloms, P; Madeja, M; Musshoff, U; Speckmann, EJ | 1 |
| Cotton, P | 1 |
| Kunow, M; Löschmann, PA; Wachtel, H | 1 |
| Annala, AJ; Baudry, M; Thompson, RF; Tocco, G | 1 |
| Ozawa, S; Takeuchi, T; Tsuzuki, K | 1 |
| Boddeke, HW; Massieu, L; Mengod, G; Palacios, JM; Rocamora, N | 1 |
| Beninger, RJ; Boegman, RJ; Cockhill, J; Jhamandas, K | 1 |
| Hansen, JJ; Krogsgaard-Larsen, P; Miledi, R; Nielsen, B; Schousboe, A; Wahl, P | 1 |
| Gottmann, K; Lessmann, V; Lux, HD | 1 |
| Carlà, V; Moroni, F | 1 |
| Fedorov, NB; Reymann, KG; Screbitsky, VG | 1 |
| Jonas, P; Sakmann, B | 1 |
| Alexander, SP; Curtis, AR; Hill, SJ; Kendall, DA | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Bloms, P; Madeja, M; Müsch-Nittel, K; Musshoff, U; Speckmann, EJ | 1 |
| Donevan, SD; Rogawski, MA; Subramaniam, S | 1 |
| Maruyama, M; Nakazawa, M; Takeda, K | 1 |
| Haley, JE; Kitto, KF; Wilcox, GL | 1 |
| Barnes, CA; Foster, TC; McNaughton, BL; Rao, G | 2 |
| Baudry, M; Bernard, J; Massicotte, G | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Garrone, B; Pittaluga, A; Raiteri, M | 1 |
| Madsen, U; Wong, EH | 1 |
| Blackstone, CD; Huganir, RL; Levey, AI; Martin, LJ; Moss, SJ; Price, DL | 1 |
| Honoré, T; Jacobsen, P; Stephens, DN; Turski, L | 1 |
| Jane, DE; Mayer, ML; Patneau, DK; Watkins, JC | 1 |
| Clark, B; Mobbs, P | 1 |
| Bobichon, C; Cordi, A; Curutchet, P; de Carvalho, LP; Guet, T; Lambolez, B; Lepagnol, JM; Moreau, C; Randle, JC | 1 |
| Andersen, CF; Frandsen, A; Schousboe, A | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Bochet, P; Curutchet, P; Lambolez, B; Prado de Carvalho, L; Rossier, J; Stinnakre, J | 1 |
| Buonanno, A; Gallo, V; Hayes, WP; Upson, LM; Vyklicky, L; Winters, CA | 1 |
| Miller, DD; Uretsky, NJ; Wallace, LJ; Willins, DL | 1 |
| Curras, MC; Dingledine, R | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Yamada, S; Yoshimura, M | 1 |
| Aleppo, G; Canonico, PL; Casabona, G; Copani, A; Genazzani, AA; Nicoletti, F; Scapagnini, U | 1 |
| Fain, GL; Yazejian, B | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Chen, L; Huang, LY | 1 |
| Bleakman, D; Brorson, JR; Chard, PS; Miller, RJ | 1 |
| Donevan, SD; Jones, SM; Rogawski, MA | 1 |
| Barnard, EA; Henley, JM; Nielsen, M | 1 |
| Martin, D; McNamara, JO; Nadler, JV | 1 |
| Petralia, RS; Wenthold, RJ | 1 |
| Cha, JH; Makowiec, RL; Penney, JB; Young, AB | 1 |
| Carling, RW; Donald, AE; Foster, AC; Grimwood, S; Kemp, JA; Leeson, PD; Marshall, GR; Priestley, T; Smith, JD | 1 |
| Gordon, FJ; Pawloski-Dahm, C | 1 |
| Abutidze, K; Ambrosini, A; Barnard, EA; Brackley, P; Henley, JM; Kerry, C; Mellor, I; Rodriguez-Ithurralde, D; Sudan, H; Usherwood, PN | 1 |
| McIlhinney, RA; Smith, AL | 1 |
| Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Boldry, RC; Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Cha, JH; Davis, RE; Wilmot, GR | 1 |
| Kawai, N; Nakajima, T; Robinson, HP; Shimazaki, K; Takenawa, T | 1 |
| Balázs, R; Hack, N; Kumar, KN; Michaelis, E; Resink, A; Van der Valk, JB | 1 |
| Lodge, D; Millar, JD; Pralong, E | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 2 |
| Ishimaru, M; Kurumaji, A; Toru, M | 1 |
| Baudry, M; Shahi, K | 1 |
| Crawley, JN; Finiels-Marlier, F; Leppin, C; Montpied, P; Paul, SM | 1 |
| Parks, TN; Zhou, N | 2 |
| Dildy-Mayfield, JE; Harris, RA | 1 |
| Greenberger, V; Segal, M | 1 |
| Dure, LS; Penney, JB; Young, AB | 2 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Baudry, M; Maren, S; Shors, TJ; Thompson, RF; Tocco, G | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 2 |
| Mishina, M; Nagahari, K; Sakimura, K; Uchino, S | 1 |
| Cai, NS; Erdö, SL | 1 |
| Chiamulera, C; Costa, S; Reggiani, A; Valerio, E | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Aronica, E; Casabona, G; Catania, MV; Contestabile, A; Genazzani, AA; Nicoletti, F; Virgili, M | 1 |
| Bleakman, D; Chard, PS; Glaum, SR; Miller, RJ; Rusin, KI | 1 |
| Ogita, K; Yoneda, Y; Zuo, P | 1 |
| Supko, DE; Wallace, LJ | 1 |
| Randic, M; Rusin, KI; Ryu, PD | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Kelso, SR; Leonard, JP; Nelson, TE | 1 |
| Calligaro, DO; Lodge, D; McQuaid, LA; Mitch, CH; O'Malley, PJ; Ornstein, PL; Schoepp, DD; Smith, EC; South, KK; True, RA | 1 |
| Martin, D; Savage, DD; Swartzwelder, HS | 1 |
| Baudry, M; Massicotte, G; Standley, S; Thompson, RF; Tocco, G | 1 |
| Arvin, B; Lekieffre, D; Meldrum, B; Moncada, C | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 2 |
| Lodge, D; Zeman, S | 1 |
| Oostveen, JA; Pregenzer, JF; Williams, LR | 1 |
| McDonald, JW; Schoepp, DD | 1 |
| Hampson, DR; Huang, XP; Walter, JA; Wells, JW; Wright, JL | 1 |
| Okada, D | 1 |
| Bahr, BA; Hall, RA; Kessler, M; Lynch, G; Sumikawa, K; Suppiramaniam, V; Vodyanoy, V | 1 |
| Brehm, L; Christensen, IT; Ebert, B; Krogsgaard-Larsen, P; Madsen, U; Nielsen, B | 1 |
| Davies, JA; Dickie, BG; Lewis, MJ | 1 |
| Bruhn, T; Diemer, NH; Frank, L | 1 |
| Baudry, M; Fitzpatrick, JS; Shahi, K | 1 |
| Bonhaus, DW; McNamara, JO | 1 |
| Gale, K; Miller, LP; Murray, TF; Zhong, P | 1 |
| Balchen, T; Diemer, NH | 1 |
| Budai, D; Larson, AA; Wilcox, GL | 1 |
| East, SJ; Garthwaite, J | 1 |
| Baganoff, MP; Davies, MS; Grishin, EV; Lanthorn, TH; Volkova, TM; Watson, GB; Wiegand, RC | 1 |
| Baird, JG; Challiss, RA; Nahorski, SR | 1 |
| Chalmers, DT; McCulloch, J | 1 |
| Baudry, M; Hauge, S; Massicotte, G | 2 |
| Bettler, B; Egebjerg, J; Heinemann, S; Hermans-Borgmeyer, I | 1 |
| Giacobini, E; Matsuoka, Y; Rakonczay, Z | 1 |
| Courtney, MJ; Nicholls, DG | 1 |
| Gaviraghi, G; Giberti, A; Ratti, E; van Amsterdam, FT | 1 |
| de Barry, J; Gombos, G; Viennot, F | 1 |
| Barnard, EA; Bond, A; Henley, JM | 1 |
| Albensi, BC; Artman, LD; Jackson, H; Jasys, VJ; Mueller, AL; Nemeth, EF; Parks, TN; Saccomano, NA; Volkmann, RA | 1 |
| Harabayashi, M; Kushiya, E; Mishina, M; Mori, H; Nagahari, K; Sakimura, K; Uchino, S | 1 |
| Jones, MG; Lodge, D; Palmer, AJ | 1 |
| Henley, JM; Johnston, GA | 1 |
| Supko, DE; Uretsky, NJ; Wallace, LJ | 1 |
| Baudry, M; Shors, TJ; Thompson, RF; Tocco, G | 1 |
| Johnson, BG; Monn, JA; Schoepp, DD; True, RA | 1 |
| Doudou, N; Kito, S; Miyoshi, R; Nomoto, T | 1 |
| Cha, JH; Dure LS, IV; Penney, JB; Sakurai, SY; Young, AB | 1 |
| Ito, E; Kudo, Y; Nakamura, T | 1 |
| Baudry, M; Devgan, KK; Hauge, SA; Thompson, RF; Tocco, G; Weiss, C | 1 |
| Cotman, CW; Koh, JY; Lin, A; Palmer, E | 1 |
| Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Blazynski, C; Linn, DM; Massey, SC; Redburn, DA | 1 |
| Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ | 1 |
| Gallo, V; Levi, G; Patrizio, M | 2 |
| Mayer, ML; Patneau, DK | 1 |
| Monyer, H; Seeburg, PH; Wisden, W | 1 |
| Dodd, PR; Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Chiu, SY; Jensen, AM | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Shreve, PE; Uretsky, NJ | 4 |
| Connor, JA; Dickinson, MH; Linden, DJ; Smeyne, M | 1 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Cull-Candy, SG; Farrant, M | 1 |
| Artola, A; Kato, N; Singer, W | 1 |
| MacVicar, BA; Tse, FW; Weiss, S | 1 |
| Chang, YC; Lee, YH; Leng, CH; Lin, YH | 1 |
| Cha, JJ; Makowiec, RL; Penney, JB; Young, AB | 1 |
| Eaton, SA; Roberts, WA; Salt, TE | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Jacques-Berg, W; Patel, AJ; Rodriguez, J | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R | 1 |
| Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Boldry, RC; Uretsky, NJ; Wallace, LJ; Willins, DL | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Aroniadou, VA; Teyler, TJ | 1 |
| Garthwaite, J; Southam, E | 1 |
| Christenson, J; Grillner, S | 1 |
| Hu, GY; Storm, JF | 1 |
| Cai, NS; Erdö, SL; Kiss, B | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 2 |
| Cull-Candy, SG; Traynelis, SF | 1 |
| Burnashev, N; Herb, A; Keinänen, K; Köhler, M; Sakmann, B; Seeburg, PH; Sommer, B; Takagi, T; Verdoorn, TA; Wisden, W | 1 |
| Hećimović, H; Randić, M; Ryu, PD | 1 |
| Mayer, ML | 1 |
| Ambrosini, A; Barnard, EA; Prestipino, G | 1 |
| Hartley, M; Heinemann, S; Hollmann, M | 1 |
| Audinat, E; Crepel, F; Geoffroy, M; Hamon, B; Kado, RT; Lambolez, B; Rossier, J | 1 |
| Beal, MF; Ferrante, RJ; Kowall, NW; Swartz, KJ | 1 |
| Legendre, P; Westbrook, GL | 1 |
| Connor, JA; Linden, DJ | 1 |
| Amaya, Y; Hattori, S; Kawamoto, S; Mishina, M; Miyagi, Y; Okuda, K; Onishi, H | 1 |
| Franke, C; Hatt, H; Rosenheimer, JL; Smith, DO; Zufall, F | 1 |
| Ambros-Ingerson, J; Larson, J; Lynch, G; Xiao, P | 1 |
| Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N | 1 |
| Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A | 1 |
| Aniksztejn, L; Ben-Ari, Y; Bregestovski, P | 1 |
| Cherubini, E; Nistri, A | 1 |
| Uretsky, NJ; Wallace, LJ | 1 |
| Chapman, AG; Meldrum, BS; Smith, SE | 1 |
| Jones, MG; Lodge, D | 1 |
| Arvin, B; Le Peillet, E; Meldrum, BS; Moncada, C | 1 |
| Beattie, DT; Bruhn, T; Curtis, DR; Diemer, NH; Ebert, B; Ferkany, JW; Johansen, JS; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Arnold, MB; Elzey, T; Leander, JD; Lodge, D; Ornstein, PL; Paschal, JW; Schoepp, DD | 1 |
| Leander, JD; Ornstein, PL; Salhoff, CR; Schoepp, DD | 1 |
| Ishii, T; Masu, M; Mizuno, N; Moriyoshi, K; Nakanishi, S; Shigemoto, R | 1 |
| Honoré, T; Jähnig, P; Jenner, P; Kunow, M; Lange, KW; Löschmann, PA; Marsden, CD; Rettig, KJ; Turski, L; Wachtel, H | 1 |
| Aniksztejn, L; Ben-Ari, Y | 1 |
| Barnard, EA; Henley, JM | 3 |
| Bonhaus, DW; Cao, Z; Crain, BJ; Friedman, AH; Hosford, DA; McNamara, JO; Nadler, JV; Okazaki, MM | 1 |
| Baudry, M; Lynch, G; Massicotte, G; Vanderklish, P | 1 |
| Larson, J; Lynch, G | 1 |
| Bowie, D; Smart, TG | 2 |
| Ferriero, DM; Simon, RP | 1 |
| Gallagher, JP; Zheng, F | 1 |
| Brewster, DW; Hopkins, WE; Warren, J | 1 |
| Sherman, AD | 1 |
| Everitt, BJ; Marston, HM; Page, KJ; Robbins, TW; Wilkinson, LS | 1 |
| Drejer, J; Honoré, T; Schousboe, A; Wahl, P | 1 |
| Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J | 1 |
| Ebert, B; Ferkany, JW; Holm, T; Johansen, TN; Jones, BE; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Ito, M; Karachot, L | 2 |
| Brehm, L; Jørgensen, FS; Krogsgaard-Larsen, P; Madsen, U; Schaumburg, K | 1 |
| Cha, JH; Drejer, J; Honoré, T; Nielsen, EO; Young, AB | 1 |
| Gallo, V; Giovannini, C; Levi, G | 1 |
| Glaum, SR; Holzwarth, JA; Miller, RJ | 1 |
| Gelhard, RE; Insel, TR; Miller, LP | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Butterworth, RF; Cotman, CW; Giguere, JF; Peterson, C | 1 |
| Baimbridge, KG; Choi, DW; Koh, J; Weiss, JH | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Burgoyne, RD; Cambray-Deakin, MA; Foster, AC | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA | 1 |
| Albin, RL; Cha, JH; Gilman, S; Makowiec, RL; Young, AB | 1 |
| Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H | 1 |
| Dawson, TL; Dingledine, R; Nicholas, RA | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Meldrum, BS; Smith, SE | 1 |
| Bockaert, J; Charpentier, N; Dumuis, A; Pin, JP; Sebben, M | 1 |
| Boos, R; Müller, F; Wässle, H | 1 |
| Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J; Shand, A | 1 |
| Thomson, AM | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Bian, XP; Martin, D; Morrisett, RA; Swartzwelder, HS; Wilson, WA | 1 |
| Ehrlich, D; Morgan, IG; Tung, NN | 1 |
| Anis, NA; Jones, MG; Lodge, D | 1 |
| Birch, PJ; Hayes, AG; Rogers, H | 1 |
| Anderson, MC; Chung, EY; Van Woert, MH | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Baudry, M; Kessler, M; Lynch, G; Massicotte, G | 1 |
| Brooks, DN; Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J | 1 |
| Blockaert, J; Finiels-Marlier, F; le Peuch, C; Manzoni, OJ; Sassetti, I; Sladeczek, FA | 1 |
| Choi, DW; Hartley, DM; Koh, J; Weiss, JH | 1 |
| Crawford, RD; Johnson, DD; Pedder, SC; Tuchek, JM; Wilcox, RI | 1 |
| Altar, CA; Baudry, M; Cotman, C; Monaghan, D | 1 |
| Erdö, SL; Wolff, JR | 2 |
| Cools, AR; de Vries, TJ; Jaspers, RM | 2 |
| Lory, P; Nargeot, J; Pin, JP; Rassendren, FA | 1 |
| Herb, A; Keinänen, K; Sakmann, B; Seeburg, PH; Sommer, B; Verdoorn, TA; Werner, P; Wisden, W | 1 |
| Johnson, BG; McQuaid, LA; Schoepp, DD; Smith, EC | 1 |
| Charpak, S; Do, KQ; Gähwiler, BH; Knöpfel, T | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Dechesne, CJ; Hunter, C; Wada, K; Wenthold, RJ | 1 |
| Baudry, M; Massicotte, G | 1 |
| Dragunow, M; Faull, RL; Jansen, KL | 2 |
| Hunter, C; Wenthold, RJ; Wheaton, KD | 1 |
| Beart, PM; Jarrott, B; Lewis, SJ; Louis, CJ; Louis, WJ; Verberne, AJ | 1 |
| Choi, DW; Goldberg, MP; Hartley, DM; Koh, JY | 1 |
| Yang, J; Zorumski, CF | 1 |
| Bockaert, J; Lory, P; Nargeot, J; Pin, JP; Rassendren, FA | 1 |
| Christensen, BN; O'Dell, TJ | 2 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Bockaert, J; Pin, JP; Van Vliet, BJ | 1 |
| Bridges, RJ; Cotman, CW; Kadri, M; Kahle, JS; Nunn, PB; Stevens, DR | 1 |
| Birch, PJ; Grossman, CJ; Hayes, AG | 2 |
| Ross, SM; Roy, DN; Spencer, PS | 1 |
| Weiss, S | 1 |
| Greenamyre, JT; Young, AB | 1 |
| Cotman, CW; Monaghan, DT; Palmer, E | 2 |
| Baudry, M; Nakagawa, Y | 1 |
| Ito, I; Sugiyama, H; Taji, H; Watanabe, M; Yamamoto, Y | 1 |
| Girdlestone, D; Thomson, AM; West, DC | 1 |
| Collingridge, GL; Davies, SN; Lester, RA; Reymann, KG | 1 |
| O'Dell, TJ | 1 |
| Westerberg, E; Wieloch, TW | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Beart, PM; Cincotta, M; Summers, RJ | 1 |
| Bowe, MA; Martin, D; Nadler, JV | 1 |
| Gordon, FJ; Leone, C | 1 |
| Drejeŕ, J; Honore, T; Nielsen, EO; Nielsen, M | 1 |
| Anwyl, R | 1 |
| Aizenman, E; Karschin, A; Lipton, SA | 1 |
| Baraban, JM; Stratton, KR; Worley, PF | 1 |
| Gulyás, J; Janáky, R; Kontro, P; Marnela, KM; Oja, SS; Varga, V | 1 |
| Ambrosini, A; Barnard, EA; Henley, JM; Krogsgaard-Larsen, P | 1 |
| Horne, AL; Simmonds, MA | 1 |
| Davies, LP; Dodd, PR; Dyer, JA; Johnston, GA; Nielsen, B; Watson, WE; Wong, LS | 1 |
| Kemp, JA; Priestley, T; Woodruff, GN | 1 |
| Honoré, T; Nielsen, M | 1 |
| Honoré, T; Krogsgaard-Larsen, P; Lauridsen, J | 2 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Cotman, CW; Monaghan, DT; Yao, D | 2 |
| Cotman, CW; Ganong, AH | 1 |
| Cross, A; Skan, W; Slater, P | 1 |
| Cotman, CW; Monaghan, DT; Westerberg, E; Wieloch, T | 1 |
| Houser, CR; Olsen, RW; Szamraj, O | 1 |
| Choi, DW; Koh, J; Peters, S | 1 |
| López-Colomé, AM; Somohano, F | 1 |
| Morgan, IG | 1 |
| Murphy, DE; Snowhill, EW; Williams, M | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Benavides, J; Carter, C; Fage, D; Scatton, B | 1 |
| Bridges, RJ; Cotman, CW; Kadri, MM; Monaghan, DT; Nunn, PB; Watkins, JC | 1 |
| Fischbach, GD; Thio, LL; Trussell, LO; Zorumski, CF | 2 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Henley, JM; Oswald, RE | 1 |
| Drejer, J; Honoré, T | 1 |
| Errami, M; Nieoullon, A | 1 |
| Blake, JF; Brown, MW; Collingridge, GL | 1 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| López-Colomé, AM; Roberts, PJ; Somohano, F | 1 |
| Baudry, M; Kessler, M; Lynch, G; Terramani, T | 1 |
| Dingledine, R; Verdoorn, TA | 1 |
| Miller, RJ; Murphy, SN | 1 |
| Belhage, B; Frandsen, A; Schousboe, A | 1 |
| Foster, AC; Gill, R; Woodruff, GN | 1 |
| Cha, JH; Honoré, T; Nielsen, EO; Penney, JB; Young, AB | 1 |
| Massey, SC; Miller, RF | 1 |
| Halpain, S; Rainbow, TC; Wieczorek, CM | 1 |
| Curtis, DR; Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Leah, JD; Peet, MJ | 1 |
| Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Nielsen, E | 1 |
| Eng, P; Hösli, E; Hösli, L; Lehmann, R | 1 |
| Kerkut, GA; Mat Jais, AM; Walker, RJ | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W | 2 |
| Arnt, J | 1 |
| Thal, LJ; Winkler, J | 1 |
| Glowinski, J; Prémont, J; Stella, N; Tencé, M | 1 |
| Klitgaard, H; Laudrup, P | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Chen, AD; Thal, LJ; Waite, JJ; Wardlow, ML | 1 |
| Dowling, JE; Grant, GB | 1 |
| Everitt, BJ; Page, KJ; Sirinathsinghji, DJ | 1 |
| Bischoff, F; Ebert, B; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Catania, MV; Hollingsworth, Z; Penney, JB; Young, AB | 2 |
| Choi, DW; Hartley, DM; Koh, JY; Weiss, JH | 1 |
| Donevan, SD; Rogawski, MA | 1 |
| Henley, JM; Hunt, SP; Jenkins, R | 1 |
| Lodge, D; Palmer, AJ | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Kelland, MD | 1 |
| Craig, CG; White, TD | 1 |
| May, PC; Robison, PM | 1 |
| Baron, SP; Woods, JH | 1 |
| Andou, Y; Enomoto, R; Kataoka, K; Mitani, A; Ogita, K; Yoneda, Y | 1 |
| Collins, GG | 1 |
| Hansen, JJ; Krogsgaard-Larsen, P; Madsen, U; Schousboe, A; Wahl, P | 1 |
| Baudry, M; Hall, RA; Kessler, M; Lynch, G; Massicotte, G | 1 |
| Birse, EF; Eaton, SA; Jane, DE; Jones, PL; Pook, PC; Porter, RH; Roberts, PJ; Sunter, DC; Udvarhelyi, PM; Wharton, B | 1 |
| Herrling, PL; Meier, CL | 1 |
| Lemaire, S; Shukla, VK | 1 |
| Sorimachi, M | 1 |
| Fischer, S; Hass, P; Keilhoff, G; Wolf, G | 1 |
| Dempesy, CW; Fontana, CJ; Richardson, DE | 1 |
| Chen, LL; Harris, RA; Lin, LH | 1 |
| Glaum, SR; Miller, RJ | 1 |
| Bahr, BA; Baudry, M; Hall, RA; Lynch, G; Suppiramaniam, V; Vodyanoy, V | 1 |
| Alagarsamy, S; Johnson, KM; Lonart, G | 1 |
| Matute, C; Miledi, R | 1 |
| Cid, ME; Ortega, A | 1 |
| Hunter, C; Petralia, RS; Vu, T; Wenthold, RJ | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Caner, H; Collins, JL; Harris, SM; Kassell, NF; Lee, KS | 1 |
| Block, F; Schwarz, M; Sontag, KH | 1 |
| Dillon-Carter, O; Freed, WJ; Kleinman, JE | 1 |
| Brackley, PT; Usherwood, PN | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| French, ED; Wang, T | 2 |
| Bowlby, MR | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Guillén, J; Laguna, J; Luquin, MR; Martínez-Lage, JM; Obeso, JA | 1 |
| Abdulla, FA; Calaminici, M; Sinden, JD; Stephenson, JD | 1 |
| Kleschevnikov, AM; Marchbanks, RM | 1 |
| Cai, N; Erdö, SL; Lakics, V | 1 |
| Everitt, BJ; Page, KJ | 1 |
| Everitt, BJ; Page, KJ; Saha, A | 1 |
| Bastian, J | 1 |
| Bockaert, J; Cragoe, EJ; Dumuis, A; Fagni, L; Manzoni, O; Prézeau, L; Sebben, M | 1 |
| Banker, G; Blackstone, CD; Craig, AM; Huganir, RL | 1 |
| Bridges, RJ; Miller, S; Nunn, PB | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Butcher, SP; Kelly, JS; Lawrence, JA; Olverman, HJ; Shirakawa, K | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Edwards, AM; Heinemann, SF; Huntley, GW; Moran, T; Morrison, JH; Rogers, SW; Vickers, JC | 1 |
| Honoré, T; Sheardown, MJ; Suzdak, PD | 1 |
| Casabona, G; Genazzani, AA; L'Episcopo, MR; Nicoletti, F; Shinozaki, H | 1 |
| Mayer, ML; Patneau, DK; Vyklicky, L | 1 |
| Abutidze, K; Barnard, EA; Kerry, CJ; Mellor, IR; Sudan, HL; Usherwood, PN | 1 |
| Schultz, K; Weiler, R | 1 |
| Fukuda, H; Hicks, TP; Kobayashi, T; Nagao, T; Oka, JI | 1 |
| Lanius, RA; Pasqualotto, BA; Shaw, CA | 1 |
| Dee, MG; Ha, LH; Spears, LC; Stanley, BG | 1 |
| Rigor, BM; Schurr, A | 1 |
| Hensley, SH; Wu, SM; Yang, XL | 1 |
| Albin, RL; Kremer, B; Tallaksen-Greene, SJ | 1 |
| Durand, J; Engberg, I; Ouardouz, M; Tarnawa, I | 1 |
| Callaway, EM; Katz, LC | 1 |
| Angelides, KJ; Benke, TA; Collingridge, GL; Jones, OT | 1 |
| Turner, JP | 1 |
| Nordholm, L; Sheardown, MJ; Suzdak, PD | 1 |
| Jane, DE; Jones, PL; Pook, PC; Salt, TE; Sunter, DC; Watkins, JC | 1 |
| Lücke, T; Neugebauer, V; Schaible, HG | 1 |
| Naarala, J; Nykvist, P; Savolainen, K; Tuomala, M | 1 |
| Gordon, FJ; Kiely, JM | 1 |
| Barrionuevo, G; Fleck, MW; Henze, DA; Palmer, AM | 1 |
| Yoneda, Y | 1 |
| Dykstra, CL; Gebhart, GF; Meller, ST | 1 |
| Mayer, ML; Wong, LA | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Iino, M; Ozawa, S | 1 |
| Block, F; Schmitt, T; Schwarz, M | 1 |
| Inglis, WL; Semba, K | 1 |
| Browne, SE; Everitt, BJ; McCulloch, J; Muir, JL; Page, KJ; Robbins, TW | 1 |
| Begtrup, M; Bräuner-Osborne, H; Calí, P; Clausen, RP; Egebjerg, J; Greenwood, JR; Hansen, KB; Nielsen, B | 1 |
| Bräuner-Osborne, H; Madsen, U; Nielsen, B; Pickering, DS | 1 |
3 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ibotenic acid
| Article | Year |
|---|---|
Effect of GABAergic and glutamatergic drugs injected into the ventral pallidum on locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Ibotenic Acid; Kainic Acid; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin | 1991 |
Excitatory amino acid research in Alzheimer's disease: enhancement and blockade of receptor functions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Humans; Ibotenic Acid; Isoxazoles; Propionates; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate | 1993 |
[Receptive mechanisms of excitatory amino acid signals].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ischemia; Epilepsy; Ibotenic Acid; Kainic Acid; Ligands; N-Methylaspartate; Receptors, Amino Acid; Signal Transduction; Transcription Factors | 1993 |
428 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and ibotenic acid
| Article | Year |
|---|---|
N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: Acetates; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Hydrogen Bonding; In Vitro Techniques; Isoxazoles; Molecular Structure; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1996 |
Evidence that high- and low-affinity DL-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding sites reflect membrane-dependent states of a single receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Ibotenic Acid; Male; Octoxynol; Polyethylene Glycols; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Solubility; Synaptic Membranes | 1992 |
Excitatory amino acid-mediated responses and synaptic potentials in medial pontine reticular formation neurons of the rat in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Female; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Pons; Rats; Rats, Inbred Strains; Reticular Formation; Synapses | 1992 |
Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Neurotransmitter; Recombinant Proteins; Xenopus laevis | 1992 |
Modulation of AMPA and NMDA responses in rat spinal dorsal horn neurons by trans-1-aminocyclopentane-1,3-dicarboxylic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Ibotenic Acid; N-Methylaspartate; Neurons; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Spinal Cord | 1992 |
Modulation of GABA release by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate and N-methyl-D-aspartate receptors in matrix-enriched areas of the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Histocytochemistry; Ibotenic Acid; Male; Nerve Endings; Perfusion; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptosomes; Tetrodotoxin; Veratridine | 1992 |
Preferential activation of [3H]phorbol-12,13-dibutyrate binding by AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) in neonatal striatal cell cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Binding Sites; Cells, Cultured; Corpus Striatum; Cycloleucine; Glial Fibrillary Acidic Protein; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Phorbol 12,13-Dibutyrate; Phosphopyruvate Hydratase; Rats; Rats, Inbred F344 | 1992 |
Time course of glutamate receptor expression in individual oocytes of Xenopus laevis after injection of rat brain RNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electrophysiology; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, Glutamate; RNA, Messenger; Xenopus laevis | 1992 |
Neuroscientists begin to piece together more parts of Huntington's disease puzzle.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Brain Chemistry; Disease Models, Animal; Fibroblast Growth Factors; Humans; Huntington Disease; Ibotenic Acid; Kainic Acid; Lactates; Lactic Acid; Rats | 1992 |
NBQX (6-nitro-sulfamoyl-benzo-quinoxaline-dione) and CPP (3-carboxy-piperazin-propyl phosphonic acid) potentiate dopamine agonist induced rotations in substantia nigra lesioned rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Apomorphine; Dopamine Agents; Drug Synergism; Ibotenic Acid; Lisuride; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1992 |
Learning of a hippocampal-dependent conditioning task changes the binding properties of AMPA receptors in rabbit hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Mapping; Conditioning, Classical; Conditioning, Eyelid; Hippocampus; Ibotenic Acid; Male; Phencyclidine; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1992 |
Agonist- and subunit-dependent potentiation of glutamate receptors by a nootropic drug aniracetam.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Psychotropic Drugs; Pyrrolidinones; Rats; Receptors, Glutamate; Xenopus laevis | 1992 |
Administration of quinolinic acid in the rat hippocampus induces expression of c-fos and NGFI-A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Hippocampus; Ibotenic Acid; In Situ Hybridization; Injections, Intraperitoneal; Male; Oligonucleotide Probes; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
Excitotoxic lesions of rat basal forebrain: differential effects on choline acetyltransferase in the cortex and amygdala.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Basal Ganglia; Cerebral Cortex; Choline O-Acetyltransferase; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Prosencephalon; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1992 |
Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoxazoles; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Oocytes; Propionates; Receptors, Amino Acid; RNA, Messenger; Stereoisomerism; Xenopus laevis | 1992 |
Evans blue reduces macroscopic desensitization of non-NMDA receptor mediated currents and prolongs excitatory postsynaptic currents in cultured rat thalamic neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evans Blue; Female; Glutamates; Ibotenic Acid; Ion Channel Gating; Neurons; Pregnancy; Quisqualic Acid; Rats; Receptors, Amino Acid; Synapses; Thalamus | 1992 |
General anaesthetics inhibit the responses induced by glutamate receptor agonists in the mouse cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics; Animals; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Mice; N-Methylaspartate; Receptors, Glutamate | 1992 |
Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Phenols; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1992 |
Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane Permeability; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Transport; Kainic Acid; Pyramidal Tracts; Rats; Receptors, Glutamate | 1992 |
Activation of a metabotropic excitatory amino acid receptor potentiates A2b adenosine receptor-stimulated cyclic AMP accumulation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotransformation; Cerebral Cortex; Cyclic AMP; Cycloleucine; Female; Guinea Pigs; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Male; N-Methylaspartate; Receptors, Amino Acid; Receptors, Purinergic; Vasodilator Agents | 1992 |
Suppression of a calcium current by CNQX and kynurenate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Calcium Channel Blockers; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ictaluridae; Kynurenic Acid; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
Tunicamycin-induced inhibition of functional expression of glutamate receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ion Channels; Kainic Acid; Oligosaccharides; Oocytes; Quisqualic Acid; Receptors, Glutamate; RNA; Tunicamycin; Xenopus laevis | 1992 |
1,10-Diaminodecane and 1,12-diaminododecane block NMDA receptor currents by an open channel mechanism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Diamines; Electrophysiology; Female; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
Evidence that [3H]glutamate binding sites are masked by biologically relevant endogenous factor on cell membranes of frog spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cytosol; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Piperazines; Quisqualic Acid; Rana catesbeiana; Spinal Cord | 1992 |
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Cycloleucine; Hemoglobins; Hydroxylamine; Hydroxylamines; Hyperalgesia; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Spinal Cord; Time Factors | 1992 |
Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Models, Neurological; Nerve Fibers; Neurons; Pyramidal Tracts; Rats; Synapses | 1992 |
Potassium-induced depolarization of rat telencephalic synaptoneurosomes increases [3H]amino-3-hydroxy-5-methylisoxazole-4-propionate receptor binding.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Egtazic Acid; Electrophysiology; Ibotenic Acid; Potassium; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Synaptosomes; Telencephalon; Verapamil | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. II. Evidence for functional cooperation and for coexistence on the same axon terminal.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dizocilpine Maleate; Drug Interactions; Hippocampus; Ibotenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Heterocyclic excitatory amino acids. Synthesis and biological activity of novel analogues of AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Electrophysiology; Heterocyclic Compounds; Ibotenic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship | 1992 |
Biochemical characterization and localization of a non-N-methyl-D-aspartate glutamate receptor in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Ibotenic Acid; Immunoblotting; Immunohistochemistry; Male; Molecular Weight; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Solubility; Tissue Distribution | 1992 |
Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Electromyography; Ibotenic Acid; Kindling, Neurologic; Locomotion; Male; Mice; Muscle Spasticity; Quinoxalines; Rats; Rats, Inbred Strains; Reflex; Spinal Cord | 1992 |
Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Ibotenic Acid; Isomerism; Kainic Acid; Kinetics; Mathematics; Mice; Mice, Inbred C57BL; Models, Neurological; Neurons; Pyrimidinones; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Structure-Activity Relationship; Uracil | 1992 |
Transmitter-operated channels in rabbit retinal astrocytes studied in situ by whole-cell patch clamping.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Bicuculline; Chloride Channels; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Membrane Proteins; Quisqualic Acid; Rabbits; Receptors, GABA-A; Retina; Time Factors | 1992 |
Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Electrophysiology; Evoked Potentials; Female; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Structure-Activity Relationship; Synapses; Xenopus | 1992 |
Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Pertussis Toxin; Quisqualic Acid; Time Factors; Virulence Factors, Bordetella | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
In the GluR1 glutamate receptor subunit a glutamine to histidine point mutation suppresses inward rectification but not calcium permeability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Base Sequence; Calcium; Calcium Channels; Cloning, Molecular; Evoked Potentials; Glutamates; Glutamine; Histidine; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oocytes; Plasmids; Quinoxalines; Receptors, Glutamate; Receptors, Neurotransmitter; Transcription, Genetic; Xenopus laevis | 1992 |
Molecular cloning and development analysis of a new glutamate receptor subunit isoform in cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cerebellum; Cloning, Molecular; DNA; Ibotenic Acid; Ion Channels; Isomerism; Kainic Acid; Molecular Sequence Data; Nucleic Acid Hybridization; Oocytes; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Transcription, Genetic | 1992 |
alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonists in the nucleus accumbens and ventral pallidum decrease the hypermotility response to psychostimulant drugs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Globus Pallidus; Glutamine; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Nucleus Accumbens; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1992 |
Selectivity of amino acid transmitters acting at N-methyl-D-aspartate and amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Chlorides; Ibotenic Acid; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1992 |
Fast excitatory postsynaptic potentials and the responses to excitant amino acids of sympathetic preganglionic neurons in the slice of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1992 |
Nootropic drugs positively modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-sensitive glutamate receptors in neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Ibotenic Acid; Kinetics; Models, Neurological; Neurons; Psychotropic Drugs; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Membranes | 1992 |
Excitatory amino acid receptors on isolated retinal ganglion cells from the goldfish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retinal Ganglion Cells; Sodium | 1992 |
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neu
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dantrolene; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Verapamil | 1992 |
Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Electrophysiology; Feedback; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Nerve Tissue Proteins; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Trigeminal Caudal Nucleus | 1992 |
Calcium directly permeates kainate/alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptors in cultured cerebellar Purkinje neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Cells, Cultured; Fluorescent Antibody Technique; Ibotenic Acid; Kainic Acid; Membrane Potentials; Purkinje Cells; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Cations, Divalent; Cells, Cultured; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Characterisation of an allosteric modulatory protein associated with alpha-[3H]amino-3-hydroxy-5-methylisoxazolepropionate binding sites in chick telencephalon: effects of high-energy radiation and detergent solubilisation.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Centrifugation, Density Gradient; Chickens; Dose-Response Relationship, Radiation; Glucosides; Ibotenic Acid; Telencephalon; Tritium | 1992 |
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Magnesium; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains | 1992 |
Light and electron immunocytochemical localization of AMPA-selective glutamate receptors in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Blotting, Northern; Brain; Brain Chemistry; Electrophoresis, Polyacrylamide Gel; Ibotenic Acid; Immunohistochemistry; Male; Microscopy, Electron; Microscopy, Immunoelectron; Molecular Sequence Data; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tissue Embedding | 1992 |
Multiple states of rat brain (RS)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors as revealed by quantitative autoradiography.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Ibotenic Acid; Kinetics; Male; Mathematics; Models, Theoretical; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Thiocyanates; Tritium | 1992 |
Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Cell Membrane; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Evoked Potentials; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Male; Neurons; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tritium | 1992 |
Evidence for a kynurenate-insensitive glutamate receptor in nucleus tractus solitarii.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aorta; Blood Pressure; Cycloleucine; Electric Stimulation; Female; Heart Rate; Ibotenic Acid; Kynurenic Acid; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Purified unitary kainate/alpha-amino-3-hydroxy-5-methylisooxazole-propionate (AMPA) and kainate/AMPA/N-methyl-D-aspartate receptors with interchangeable subunits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Kainic Acid; Ligands; Macromolecular Substances; Molecular Weight; Nerve Tissue Proteins; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Xenopus laevis | 1992 |
Effects of acromelic acid A on the binding of [3H]-kainic acid and [3H]-AMPA to rat brain synaptic plasma membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Female; Ibotenic Acid; Kainic Acid; Kinetics; Quinolines; Radioligand Assay; Rats; Rats, Inbred Strains; Synaptic Membranes | 1992 |
CNQX binding to non-NMDA glutamate receptors in canine cerebro-cortical crude synaptosomal membranes: pharmacological characterization and comparison of binding parameters in dogs with congenital portosystemic encephalopathy and control dogs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Dogs; Female; Hepatic Encephalopathy; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; Membranes; Quinoxalines; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Stimulation of locomotor activity by intra-accumbens AMPA is not inhibited by neonatal 6-hydroxydopamine-induced lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Ibotenic Acid; Injections; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains | 1992 |
Glutamic acid-insensitive [3H]kainic acid binding in goldfish brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; Ligands; Neurotoxins; Tissue Distribution; Tritium | 1992 |
Purification of AMPA type glutamate receptor by a spider toxin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cattle; Cerebellum; Chloride Channels; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Liposomes; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Spider Venoms | 1992 |
NMDA treatment and K(+)-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellar Cortex; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1992 |
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
L-glutamate-evoked release of dopamine from synaptosomes of the rat striatum: involvement of AMPA and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical; Synaptosomes | 1992 |
Alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding to human cerebral cortical membranes: minimal changes in postmortem brains of chronic schizophrenics.
Topics: 4-Chloromercuribenzenesulfonate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Cerebral Cortex; Chronic Disease; Female; Humans; Ibotenic Acid; Male; Membranes; Middle Aged; Reference Values; Schizophrenia; Tissue Distribution; Tritium | 1992 |
Increasing binding affinity of agonists to glutamate receptors increases synaptic responses at glutamatergic synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Azides; Binding, Competitive; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Perchlorates; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium Azide; Sodium Compounds; Synapses; Telencephalon; Thiocyanates | 1992 |
Failure of a protein synthesis inhibitor to modify glutamate receptor-mediated neurotoxicity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anisomycin; Cell Death; Glutamate Decarboxylase; Glutamates; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Gamma-D-glutamylaminomethyl sulfonic acid (GAMS) distinguishes subtypes of glutamate receptor in the chick cochlear nucleus (nuc. magnocellularis).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Chickens; Cochlea; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Kainic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Ethanol; Female; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oocytes; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Xenopus laevis | 1992 |
Acidic amino acids evoke a smaller [Ca2+]i rise in GABAergic than non-GABAergic hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Ibotenic Acid; Interneurons; Microscopy, Fluorescence; N-Methylaspartate; Rats | 1992 |
Compartmentalization of excitatory amino acid receptors in human striatum.
Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Caudate Nucleus; Corpus Striatum; Dizocilpine Maleate; Female; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Putamen; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Long-term potentiation is associated with increased [3H]AMPA binding in rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Autoradiography; Electric Stimulation; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Male; Multivariate Analysis; Phencyclidine; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Synapses; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Mutations in a putative agonist binding region of the AMPA-selective glutamate receptor channel.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Glutamates; Ibotenic Acid; Kainic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Recombinant Proteins; Sequence Homology, Nucleic Acid; Xenopus laevis | 1992 |
The effects of kainate and the glutamate agonist, AMPA, are not separable in rat neocortical cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Neurons; Pregnancy; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1992 |
Domoic acid toxicity in rats and mice after intracerebroventricular administration: comparison with excitatory amino acid agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Neurotoxins; Rats; Rats, Inbred Strains | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Melittin enhances excitatory amino acid release and AMPA-stimulated 45Ca2+ influx in cultured neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Enzyme Activation; Granulocytes; Ibotenic Acid; Melitten; Neurons; Osmolar Concentration; Phospholipases A; Phospholipases A2; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Drug Synergism; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Myocardial Contraction; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1992 |
Presence of the binding of a variety of ligands related to ionotropic excitatory amino acid receptors in rat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Glycine; Ibotenic Acid; Kinetics; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Tritium | 1992 |
AMPA glutamate receptor activation in the posterior zona incerta inhibits amphetamine- and apomorphine-induced stereotypy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Dextroamphetamine; Diencephalon; Ibotenic Acid; Injections; Male; Motor Activity; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Stereotyped Behavior | 1992 |
Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Cesium; Colforsin; Glycine; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neurokinin A; Neurons; Peptides; Phorbol Esters; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P; Tachykinins | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Protein kinase C-mediated enhancement of NMDA currents by metabotropic glutamate receptors in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Calcium; Dose-Response Relationship, Drug; Ibotenic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 1992 |
Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glycine; Ibotenic Acid; Male; Quinazolines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1992 |
Effects of prenatal ethanol exposure on hippocampal ionotropic-quisqualate and kainate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain Mapping; Dendrites; Female; Fetal Alcohol Spectrum Disorders; Hippocampus; Ibotenic Acid; Neuronal Plasticity; Neurons; Pregnancy; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1992 |
Phospholipase A2-induced changes in AMPA receptor: an autoradiographic study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ibotenic Acid; Male; Oxadiazoles; Phospholipases A; Phospholipases A2; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Neurotransmitter; Tritium | 1992 |
Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Brain Ischemia; Dose-Response Relationship, Drug; Hippocampus; Ibotenic Acid; Male; N-Methylaspartate; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyramidal Tracts; Rats; Rats, Wistar | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
Pharmacological characterization of non-NMDA subtypes of glutamate receptor in the neonatal rat hemisected spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Methohexital; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Induction of cobalt accumulation by excitatory amino acids within neurons of the hippocampal slice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cobalt; Gerbillinae; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; N-Methylaspartate; Neurons | 1992 |
The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Drug Synergism; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid | 1992 |
Interaction of domoic acid and several derivatives with kainic acid and AMPA binding sites in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Molecular Conformation; Neurotoxins; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Structure-Activity Relationship | 1992 |
Two pathways of cyclic GMP production through glutamate receptor-mediated nitric oxide synthesis.
Topics: 1-Methyl-3-isobutylxanthine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cyclic GMP; Cycloleucine; Ibotenic Acid; In Vitro Techniques; Male; Nitric Oxide; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Glutamate | 1992 |
Functional reconstitution of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Lipid Bilayers; Prosencephalon; Protein Binding; Rats; Receptors, AMPA; Receptors, Neurotransmitter | 1992 |
Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain; Ibotenic Acid; Isoxazoles; Rats; Receptors, Amino Acid; Stereoisomerism; Structure-Activity Relationship | 1992 |
NMDA-induced release of nitric oxide potentiates aspartate overflow from cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Quisqualic Acid; Rats; Rats, Wistar | 1992 |
Regional cerebral protein synthesis after transient ischemia in the rat: effect of the AMPA antagonist NBQX.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ibotenic Acid; Ischemic Attack, Transient; Male; Methionine; Nerve Tissue Proteins; Neurons; Organ Specificity; Quinoxalines; Rats; Rats, Wistar; Sulfur Radioisotopes | 1992 |
Effect of seizure activity and calpain inhibitor I on LTP in juvenile hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Glycoproteins; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Neuronal Plasticity; Phospholipases A; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
The AMPA antagonist, NBQX, protects against ischemia-induced loss of cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Ibotenic Acid; Ischemic Attack, Transient; Male; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar | 1992 |
Modulation of N-methyl-D-aspartate and (R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) responses of spinal nociceptive neurons by a N-terminal fragment of substance P.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Ibotenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 1992 |
Actions of a metabotropic glutamate receptor agonist in immature and adult rat cerebellum.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebellum; Cycloleucine; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Purkinje Cells; Quinoxalines; Rats; Receptors, Glutamate | 1992 |
Polyamine spider toxins are potent un-competitive antagonists of rat cortex excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Ibotenic Acid; In Vitro Techniques; Indoleacetic Acids; Kainic Acid; Male; N-Methylaspartate; Polyamines; Rats; Receptors, Neurotransmitter; Spider Venoms; Xenopus laevis | 1992 |
Role for ionotropic and metabotropic receptors in quisqualate-stimulated inositol polyphosphate accumulation in rat cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Cycloleucine; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Selective alterations in glutamate receptor subtypes after unilateral orbital enucleation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Eye Enucleation; Functional Laterality; Glutamates; Ibotenic Acid; Kainic Acid; Male; Ocular Physiological Phenomena; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Purinergic; Reference Values; Time Factors; Tritium; Visual Cortex; Visual Pathways | 1991 |
Phosphatidylserine increases the affinity of the AMPA/quisqualate receptor in rat brain membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cholesterol; Ibotenic Acid; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Sphingomyelins; Synaptic Membranes; Synaptic Transmission; Telencephalon | 1991 |
Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Brain Chemistry; Cerebellum; Cloning, Molecular; DNA; Ibotenic Acid; Kainic Acid; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Oocytes; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Tissue Distribution; Transfection; Xenopus | 1991 |
Effects of L-beta-N-methylamino-L-alanine (L-BMAA) on the cortical cholinergic and glutamatergic systems of the rat.
Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Choline O-Acetyltransferase; Cyanobacteria Toxins; Ibotenic Acid; Injections, Intraventricular; Male; Parasympathetic Nervous System; Quinuclidinyl Benzilate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Cycloleucine; Cytoplasm; Ibotenic Acid; Kinetics; N-Methylaspartate; Neurotoxins; Piperidines; Quisqualic Acid; Receptors, Neurotransmitter | 1991 |
Binding of DL-[3H]-alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) to rat cortex membranes reveals two sites or affinity states.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Ibotenic Acid; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Synaptic Membranes; Tritium | 1991 |
Non-NMDA excitatory amino acid receptors in a subcellular fraction enriched in cerebellar glomeruli.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebellum; Female; Glutamates; Ibotenic Acid; Kainic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1991 |
Autoradiographic localisations of glutamatergic ligand binding sites in Xenopus brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain Chemistry; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Xenopus | 1991 |
Arylamine toxins from funnel-web spider (Agelenopsis aperta) venom antagonize N-methyl-D-aspartate receptor function in mammalian brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Cells, Cultured; Cerebellum; Cytosol; Evoked Potentials; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Structure-Activity Relationship; Synapses; Synaptic Transmission | 1991 |
A single amino acid residue determines the Ca2+ permeability of AMPA-selective glutamate receptor channels.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Calcium Channels; Glutamates; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oocytes; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus | 1991 |
Excitatory amino acids: new tools for old stories or pharmacological subtypes of glutamate receptors: electrophysiological studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Stem; Cerebral Cortex; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Wasp Venoms | 1991 |
Opposite effects of phospholipase A2 on [3H]AMPA binding in adult and neonatal membranes.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic Acid; Kinetics; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Synaptic Membranes; Telencephalon | 1991 |
Vintage amino acid meeting describes new tools for amino acid research, subtypes of metabotropic receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Humans; Ibotenic Acid; Kainic Acid; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Activation of AMPA/kainic acid glutamate receptors in the zona incerta stimulates locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diencephalon; Ibotenic Acid; Injections; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, Neurotransmitter; Substantia Nigra | 1991 |
Selective increase of AMPA binding to the AMPA/quisqualate receptor in the hippocampus in response to acute stress.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Electroshock; Hippocampus; Ibotenic Acid; Phencyclidine; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Restraint, Physical; Stress, Psychological; Synaptic Transmission | 1991 |
Comparison of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD)- and 1R,3S-ACPD-stimulated brain phosphoinositide hydrolysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Hydrolysis; Ibotenic Acid; Kainic Acid; Male; Membranes; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stimulation, Chemical | 1991 |
Effect of age on alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding sites in the rat brain studied by in vitro autoradiography.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cerebral Cortex; Hippocampus; Ibotenic Acid; Kinetics; Male; Organ Specificity; Oxadiazoles; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, Neurotransmitter; Tritium | 1991 |
2,4,5-Trihydroxyphenylalanine (6-hydroxy-dopa) displaces [3H]AMPA binding in rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Corpus Striatum; Dihydroxyphenylalanine; Ibotenic Acid; Kainic Acid; Kinetics; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Tritium | 1991 |
A 'macro' image analysis of fura-2 fluorescence to visualize the distribution of functional glutamate receptor subtypes in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Fluorescence; Fura-2; Hippocampus; Ibotenic Acid; Image Processing, Computer-Assisted; In Vitro Techniques; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease.
Topics: Adolescent; Adult; Age Factors; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding, Competitive; Caudate Nucleus; Cell Death; Child; Dizocilpine Maleate; Frontal Lobe; Glycine; Humans; Huntington Disease; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Phencyclidine; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1991 |
Classical conditioning selectively increases AMPA receptor binding in rabbit hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Conditioning, Classical; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Ligands; Male; Nictitating Membrane; Phencyclidine; Rabbits; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Cycloleucine; Embryo, Mammalian; Glutamates; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1991 |
Transient postnatal increases in excitatory amino acid binding sites in rat ventral mesencephalon.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Corpus Striatum; Glutamates; Ibotenic Acid; Kainic Acid; Mesencephalon; N-Methylaspartate; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Acetylcholine release from the rabbit retina mediated by kainate receptors.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Choline; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rabbits; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina | 1991 |
Neurochemical characterization of excitotoxin lesions in the cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Exocytosis; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Taurine | 1991 |
Kinetic analysis of interactions between kainate and AMPA: evidence for activation of a single receptor in mouse hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Mice; Neurons; Quisqualic Acid; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1991 |
Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cerebellum; Gene Expression; Hippocampus; Ibotenic Acid; Neurons; Nucleic Acid Hybridization; Oligonucleotide Probes; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; RNA Splicing; RNA, Messenger | 1991 |
Alterations in cortical [3H]kainate and alpha-[3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chronic Disease; Dizocilpine Maleate; Dogs; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Ibotenic Acid; Kainic Acid; Ligands; Tritium | 1991 |
Differential intracellular calcium responses to glutamate in type 1 and type 2 cultured brain astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Brain; Calcium; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Glial Fibrillary Acidic Protein; Glutamates; Ibotenic Acid; Immunohistochemistry; Kainic Acid; Potassium; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Purkinje Cells; Receptors, Amino Acid; Receptors, Cell Surface; Time Factors | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Cerebellum; Evoked Potentials; Glutamates; Glycine; Ibotenic Acid; In Vitro Techniques; Magnesium; Membrane Potentials; N-Methylaspartate; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Tetrodotoxin | 1991 |
GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediated.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Cerebellum; Chlorides; Cyclic GMP; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Lithium; Lithium Chloride; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nipecotic Acids; Nitroprusside; Organic Anion Transporters; Proline; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Secretory Rate; Sodium; Stimulation, Chemical | 1991 |
Developmental changes in the susceptibility to long-term potentiation of neurones in rat visual cortex slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Visual Cortex | 1991 |
Quisqualate agonists occlude kainate-induced current in cultured striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Drug Interactions; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neurons; Quisqualic Acid | 1991 |
Solubilization, characterization, and partial purification of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-, quisqualate-, kainate-sensitive L-glutamate binding sites from porcine brain synaptic junctions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chromatography; Detergents; Glutamates; Glutamic Acid; Hot Temperature; Ibotenic Acid; Kainic Acid; Octoxynol; Polyethylene Glycols; Quisqualic Acid; Solubility; Synapses | 1991 |
Presynaptic facilitation of dopamine release through D,L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors on synaptosomes from the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dipeptides; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Nerve Endings; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptosomes; Tritium | 1991 |
Cerebellar excitatory amino acid binding sites in normal, granuloprival, and Purkinje cell-deficient mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellar Cortex; Dendrites; Denervation; Ibotenic Acid; Methylazoxymethanol Acetate; Mice; Mice, Neurologic Mutants; Purkinje Cells; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1991 |
Excitatory amino acid receptors mediate synaptic responses to visual stimuli in superior colliculus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
Differential regulation of cerebellar granule neurons by two types of quisqualate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cerebellar Cortex; Cycloleucine; Diltiazem; Glutaminase; Ibotenic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Neuronal Plasticity; Neurons; Nifedipine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid electrophysiological and neurotoxic effects in the guinea-pig cochlea.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlear Microphonic Potentials; Dendrites; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Ibotenic Acid; Male; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Vestibulocochlear Nerve | 1991 |
Effects of morphine in the nucleus accumbens on stimulant-induced locomotion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Agents; Glutamine; Ibotenic Acid; Male; Morphine; Motor Activity; Neural Pathways; Nucleus Accumbens; Oligopeptides; Picrotoxin; Rats; Scopolamine; Synaptic Transmission | 1991 |
The role of endogenous dopamine in the hypermotility response to intra-accumbens AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Methyltyrosine; Amphetamine; Animals; Benzazepines; Dialysis; Dopamine; Dopamine Antagonists; Ibotenic Acid; Injections; Male; Methyltyrosines; Motor Activity; Nucleus Accumbens; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stimulation, Chemical; Sulpiride; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Chloride; Cortical Spreading Depression; Electric Stimulation; Evoked Potentials; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors; Visual Cortex | 1991 |
Intercellular action of nitric oxide in adult rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Neurons; Phorbol Esters; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Vinpocetine preferentially antagonizes quisqualate/AMPA receptor responses: evidence from release and ligand binding studies.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membranes; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium; Vinca Alkaloids | 1991 |
Localization of NMDA and AMPA receptors in rat barrel field.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Cerebral Cortex; Glycine; Ibotenic Acid; Male; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine; Tritium | 1991 |
Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Cerebellum; Electric Conductivity; Glycine; Hydrogen-Ion Concentration; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Protons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Base Sequence; Brain; DNA; Exons; Genomic Library; Glutamates; Ibotenic Acid; Ion Channels; Kinetics; Molecular Sequence Data; Oligonucleotide Probes; Organ Specificity; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Recombinant Proteins; RNA Splicing; RNA, Messenger | 1990 |
Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1990 |
Glutamate: three meetings but how many receptors? Excitatory Amino Acids 1990: a Fidia Research Foundation Symposium, Padua, Italy, May 21-26, 1990. Excitatory Amino Acid Receptors in the Brain: Functions and Disorders, Montreal, Canada, June 23-24, 1990.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; GTP-Binding Proteins; Ibotenic Acid; Ion Channel Gating; Ion Channels; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction | 1990 |
AMPA and kainate-operated channels reconstituted in artificial bilayers.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Membrane; Cholesterol; Electric Conductivity; Ibotenic Acid; Ion Channels; Kainic Acid; Lipid Bilayers; Membrane Potentials; Phosphatidylcholines; Phospholipids; Receptors, Kainic Acid; Receptors, Neurotransmitter; Xenopus | 1991 |
Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Ibotenic Acid; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Xenopus | 1991 |
Reduction of desensitization of a glutamate ionotropic receptor by antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channels; Membrane Potentials; Oocytes; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1991 |
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Biogenic Amines; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Huntington Disease; Ibotenic Acid; Kainic Acid; Male; Mesencephalon; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Substance P | 1991 |
Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Glycine; Ibotenic Acid; Ion Channels; N-Methylaspartate; Piperidines; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Vasodilator Agents | 1991 |
Participation of postsynaptic PKC in cerebellar long-term depression in culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellum; Enzyme Activation; Ibotenic Acid; In Vitro Techniques; Indoles; Mice; Naphthalenes; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Purkinje Cells; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Synaptic Membranes | 1991 |
Functional expression of the alpha 1 subunit of the AMPA-selective glutamate receptor channel, using a baculovirus system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baculoviridae; DNA, Recombinant; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; Ibotenic Acid; Insecta; Ion Channels; Kainic Acid; Kinetics; Mice; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Transfection | 1991 |
Desensitization and resensitization rates of glutamate-activated channels may regulate motoneuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Chick Embryo; Electrophysiology; Glutamates; Ibotenic Acid; Ion Channels; Kainic Acid; Motor Neurons; Quinoxalines; Quisqualic Acid; Synaptic Transmission | 1991 |
LTP changes the waveform of synaptic responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Pyrrolidinones; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Synapses | 1991 |
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P | 1991 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Selective activation of quisqualate metabotropic receptor potentiates NMDA but not AMPA responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ion Channels; N-Methylaspartate; Neurons; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Depression of a sustained calcium current by kainate in rat hippocampal neurones in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Calcium; Culture Techniques; Egtazic Acid; Electrophysiology; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurons; Rats; Rats, Inbred Strains; Sodium | 1991 |
Specificity of functional changes during normal brain aging.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; Membrane Potentials; Neuronal Plasticity; Rats; Synapses | 1991 |
The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Female; Ibotenic Acid; Male; Mice; Mice, Inbred DBA; Postural Balance; Quinoxalines; Seizures | 1991 |
Comparison of some arthropod toxins and toxin fragments as antagonists of excitatory amino acid-induced excitation of rat spinal neurones.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Arthropod Venoms; Asparagine; Female; Ibotenic Acid; Indoleacetic Acids; Iontophoresis; Microelectrodes; N-Methylaspartate; Neurons; Neurotoxins; Phenols; Phenylacetates; Polyamines; Rats; Rats, Inbred Strains; Spinal Cord; Wasp Venoms | 1991 |
Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Pyramidal Tracts; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Dizocilpine Maleate; Glycine; Ibotenic Acid; In Vitro Techniques; Indicators and Reagents; Isoxazoles; Male; Molecular Structure; Neurons; Propionates; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tritium | 1991 |
4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Ibotenic Acid; Indicators and Reagents; Kainic Acid; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Tetrazoles | 1991 |
Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Ibotenic Acid; Isoquinolines; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Molecular cloning and characterization of the rat NMDA receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Electrophysiology; Ibotenic Acid; Kainic Acid; Molecular Sequence Data; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus | 1991 |
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Callithrix; Disease Models, Animal; Drug Synergism; Ibotenic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1991 |
Novel form of long-term potentiation produced by a K+ channel blocker in the hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Ibotenic Acid; Male; N-Methylaspartate; Potassium Channels; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1991 |
Comparison of solubilised kainate and alpha-amino-3-hydroxy-5- methylisoxazolepropionate binding sites in chick cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membrane; Cerebellum; Chickens; Glucosides; Ibotenic Acid; Kainic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Solubility | 1991 |
Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus.
Topics: Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding Sites; Cell Survival; Epilepsy; Female; Hippocampus; Humans; Ibotenic Acid; Male; Neurons; Phencyclidine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values | 1991 |
Modulation of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/quisqualate receptors by phospholipase A2: a necessary step in long-term potentiation?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Calpain; Cell Membrane; Cerebellum; Electric Stimulation; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Spectrin | 1991 |
A test of the spine resistance hypothesis for LTP expression.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cold Temperature; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Interaction of 5-bromowillardiine with non-NMDA receptors expressed in Xenopus laevis oocytes injected with chick brain mRNA.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chickens; Female; Ibotenic Acid; Injections; Kainic Acid; Membrane Potentials; Neuromuscular Depolarizing Agents; Oocytes; Quisqualic Acid; Receptors, Dopamine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1991 |
Neonatal striatal NADPH-diaphorase neurons are vulnerable to quisqualate and its analogue alpha-amino-3-hydroxy-5-methyl-4-isoxazole proprionate (AMPA).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Corpus Striatum; Functional Laterality; Ibotenic Acid; NADPH Dehydrogenase; Neurons; Neurotoxins; Quisqualic Acid; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Trans-ACPD (trans-D,L-1-amino-1,3-cyclopentanedicarboxylic acid) elicited oscillation of membrane potentials in rat dorsolateral septal nucleus neurons recorded intracellularly in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Sodium | 1991 |
Metabolism of glyphosate in Sprague-Dawley rats: tissue distribution, identification, and quantitation of glyphosate-derived materials following a single oral dose.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotransformation; Chromatography, High Pressure Liquid; Feces; Glycine; Glyphosate; Ibotenic Acid; Intestinal Absorption; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
Depolarization and synaptosomal glutamine utilization.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Fractionation; Centrifugation, Zonal; gamma-Aminobutyric Acid; Glutamine; Ibotenic Acid; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes; Veratridine | 1991 |
Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Choline O-Acetyltransferase; Escape Reaction; Habituation, Psychophysiologic; Ibotenic Acid; Learning; Male; Neurons; Parasympathetic Nervous System; Prosencephalon; Rats; Rats, Inbred Strains; Reaction Time; Retention, Psychology; Space Perception | 1991 |
Development of binding sites for excitatory amino acids in cultured cerebral cortex neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; DNA; Female; Glutamates; Ibotenic Acid; Kainic Acid; Kinetics; Membrane Potentials; Membranes; Mice; Neurons; Pregnancy | 1991 |
Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: an autoradiographic study of the hippocampus.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Autoradiography; Benzoxazines; Binding Sites; Female; Glutamates; Hippocampus; Humans; Ibotenic Acid; Kainic Acid; Male; Neurons; Oxazines | 1991 |
NMDA receptor agonists derived from ibotenic acid. Preparation, neuroexcitation and neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Callosum; Dizocilpine Maleate; Ibotenic Acid; In Vitro Techniques; Nervous System; Nervous System Diseases; Piperazines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical | 1990 |
The selective ionotropic-type quisqualate receptor agonist AMPA is a potent neurotoxin in immature rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Corpus Striatum; Ibotenic Acid; Injections; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter | 1990 |
Messengers mediating long-term desensitization in cerebellar Purkinje cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Cerebellum; Cyclic GMP; Egtazic Acid; Ibotenic Acid; In Vitro Techniques; omega-N-Methylarginine; Perfusion; Pertussis Toxin; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Signal Transduction; Virulence Factors, Bordetella | 1990 |
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Computer Simulation; Ibotenic Acid; Kainic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stereoisomerism; Structure-Activity Relationship | 1990 |
Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Oxadiazoles; Oxazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Modulation of non-N-methyl-D-aspartate receptors in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Granulocytes; Ibotenic Acid; Kainic Acid; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Glutamate receptors activate Ca2+ mobilization and Ca2+ influx into astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Benzofurans; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Fluorescent Dyes; Fura-2; Glutamates; Hippocampus; Ibotenic Acid; Nickel; Nimodipine; Organ Specificity; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
The ontogeny of excitatory amino acid receptors in rat forebrain--I. N-methyl-D-aspartate and quisqualate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ammonia; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; Down-Regulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Liver; Male; N-Methylaspartate; Organ Size; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamus | 1990 |
Cortical neurons containing somatostatin- or parvalbumin-like immunoreactivity are atypically vulnerable to excitotoxic injury in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebral Cortex; Fetus; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; Mice; Muscle Proteins; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxins; Oxazoles; Parvalbumins; Somatostatin | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
The expression of excitatory amino acid binding sites during neuritogenesis in the developing rat cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebellum; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Oxazoles; Rats; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium Chloride; Carbachol; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Oxadiazoles; Oxazoles; Potassium Chloride; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Cerebellar Cortex; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Olivopontocerebellar Atrophies; Oxadiazoles; Receptors, AMPA; Receptors, Neurotransmitter; Reference Values; Spinocerebellar Degenerations; Tritium | 1990 |
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1990 |
Homomeric GluR1 excitatory amino acid receptors expressed in Xenopus oocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Ganglia, Spinal; Hippocampus; Ibotenic Acid; Kainic Acid; Membrane Proteins; Oocytes; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1990 |
Autoradiographic distribution of binding sites for the non-NMDA receptor antagonist CNQX in chick brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Chickens; Ibotenic Acid; Organ Specificity; Quinoxalines; Tritium | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Receptor site specificity for the acute effects of beta-N-methylamino-alanine in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Cyanobacteria Toxins; Glutamine; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Kinetics; Male; Mice; N-Methylaspartate; Organophosphorus Compounds; Piperazines; Receptors, Drug; Receptors, N-Methyl-D-Aspartate | 1990 |
On concanavalin A-treated striatal neurons quisqualate clearly behaves as a partial agonist of a receptor fully activated by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Concanavalin A; Corpus Striatum; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Mice; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Veratridine | 1990 |
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Cats; Electrodes; Glutamates; Glutamic Acid; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Retinal Ganglion Cells | 1990 |
Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Autoradiography; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Neurotransmitter | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Ethanol inhibition of NMDA mediated depolarizations is increased in the presence of Mg2+.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Ethanol; Female; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; N-Methylaspartate; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains | 1991 |
A quantitative analysis of the effects of excitatory neurotoxins on retinal ganglion cells in the chick.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Chickens; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Retina; Retinal Ganglion Cells; Vitreous Body | 1990 |
Philanthotoxin blocks quisqualate-, AMPA- and kainate-, but not NMDA-, induced excitation of rat brainstem neurones in vivo.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Female; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Polyamines; Quisqualic Acid; Rats; Rats, Inbred Strains; Wasp Venoms | 1990 |
Effects of hypoxia and hypoglycaemia on DC potentials recorded from the gerbil hippocampus in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cell Hypoxia; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Hypoglycemia; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membrane Potentials; N-Methylaspartate | 1990 |
The effects of inferior olive lesion on strychnine seizure.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Dizocilpine Maleate; Epilepsies, Myoclonic; Glutamates; Ibotenic Acid; Male; Olivary Nucleus; Pyridines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures; Strychnine; Tritium | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
N-Methyl-D-aspartate and quisqualate/DL-alpha-amino-3-hydroxy-5- methylisoxazole-4-propionic acid receptors: differential regulation by phospholipase C treatment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Male; Oxazoles; Phencyclidine; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Type C Phospholipases | 1990 |
Differential alterations of cortical glutamatergic binding sites in senile dementia of the Alzheimer type.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Aspartic Acid; Autoradiography; Cerebral Cortex; Female; Glutamates; Humans; Ibotenic Acid; Kainic Acid; Male; Receptors, Glutamate; Receptors, Neurotransmitter; Reference Values; Tritium | 1990 |
The glutamate receptor of the Qp-type activates protein kinase C and is regulated by protein kinase C.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Cytosol; Ibotenic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, AMPA; Receptors, Neurotransmitter; Staurosporine | 1990 |
The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium Channels; Drug Antagonism; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Mice; N-Methylaspartate; Neurons; Nifedipine; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Quisqualate receptors in epileptic fowl: the absence of coupling between quisqualate and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Brain; Chickens; Convulsants; Dose-Response Relationship, Drug; Epilepsy; Ibotenic Acid; Kinetics; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Regional distribution of alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding sites in rat brain: effect of chemical modification of SH- groups in tissue sections.
Topics: 4-Chloromercuribenzenesulfonate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Ibotenic Acid; Male; Oxazoles; Rats; Rats, Inbred Strains; Subtraction Technique; Sulfhydryl Compounds; Thiocyanates; Tissue Distribution | 1990 |
Postnatal development of the excitatory amino acid system in visual cortex of the rat. Changes in ligand binding to NMDA, quisqualate and kainate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Visual Cortex | 1990 |
Enhancement in switching motor patterns following local application of the glutamate agonist AMPA into the cat caudate nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Mapping; Cats; Caudate Nucleus; Dominance, Cerebral; Forelimb; Hindlimb; Ibotenic Acid; Locomotion; Male; Motor Activity; Motor Skills; Neurons; Oxazoles; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Effects of intrastriatal apomorphine on changes in switching behaviour induced by the glutamate agonist AMPA injected into the cat caudate nucleus.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Cats; Caudate Nucleus; Corpus Striatum; Dominance, Cerebral; Forelimb; Hindlimb; Ibotenic Acid; Locomotion; Male; Motor Activity; Motor Skills; Neck Muscles; Orientation; Oxazoles; Receptors, AMPA; Receptors, Dopamine; Receptors, Glutamate; Receptors, Neurotransmitter; Substantia Nigra | 1990 |
Zinc has opposite effects on NMDA and non-NMDA receptors expressed in Xenopus oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Electric Conductivity; Female; Ibotenic Acid; Neurons; Oocytes; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Xenopus laevis; Zinc | 1990 |
A family of AMPA-selective glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Base Sequence; Brain; Glutamates; Ibotenic Acid; Kainic Acid; Kinetics; Molecular Sequence Data; Multigene Family; Oligonucleotide Probes; Organ Specificity; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Sequence Homology, Nucleic Acid | 1990 |
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Brain; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Male; N-Methylaspartate; Pipecolic Acids; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism | 1990 |
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electric Conductivity; Electrophysiology; Hippocampus; Ibotenic Acid; Kynurenic Acid; Neurons; Potassium Channels; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Muscarinic; Receptors, Neurotransmitter | 1990 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of cerebellar granule cells in culture: effect of kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Dizocilpine Maleate; DNA; Electric Stimulation; Glutamine; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Receptor subtypes involved in, and time course of, the long-term desensitization of glutamate receptors in cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebellum; Ibotenic Acid; In Vitro Techniques; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Antibodies to a C-terminal peptide of the rat brain glutamate receptor subunit, GluR-A, recognize a subpopulation of AMPA binding sites but not kainate sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Antibodies; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Glutamates; Ibotenic Acid; Kainic Acid; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptides; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Modulation of DL-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA)/quisqualate receptors by phospholipase A2 treatment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Phospholipases A; Phospholipases A2; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Synaptic Membranes; Tritium | 1990 |
NMDA and kainic acid receptors have a complementary distribution to AMPA receptors in the human cerebellum.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Cerebellum; Female; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Solubilization and partial purification of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Cell Membrane; Chromatography, Gel; Ibotenic Acid; Kinetics; Male; Molecular Weight; Oxazoles; Radioligand Assay; Rats; Rats, Inbred Strains; Solubility; Surface-Active Agents | 1990 |
Excitotoxin-induced degeneration of rat vagal afferent neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Ibotenic Acid; Kainic Acid; Nerve Degeneration; Neurons, Afferent; Nodose Ganglion; Pressoreceptors; Rats; Rats, Inbred Strains; Vagus Nerve | 1990 |
Non-NMDA receptor-mediated neurotoxicity in cortical culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Cerebral Cortex; Drug Synergism; Ibotenic Acid; Kainic Acid; Microscopy, Phase-Contrast; Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Time Factors; Zinc | 1990 |
AMPA, kainate, and quisqualate activate a common receptor-channel complex on embryonic chick motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Binding, Competitive; Chick Embryo; Ibotenic Acid; Ion Channels; Kainic Acid; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Receptors, Cell Surface | 1988 |
A specific quisqualate agonist inhibits kainate responses induced in Xenopus oocytes injected with rat brain RNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Convulsants; Female; Ibotenic Acid; Kainic Acid; Kinetics; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA; Xenopus laevis | 1989 |
Horizontal cells isolated from catfish retina contain two types of excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Calcium; Cations, Divalent; Cell Membrane Permeability; Cells, Cultured; Concanavalin A; Convulsants; Glutamates; Ibotenic Acid; Ictaluridae; Ion Channels; Kainic Acid; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Retina; Valine; Zinc | 1989 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Complex interaction between quisqualate and kainate receptors as revealed by measurement of GABA release from striatal neurons in primary culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Concanavalin A; Corpus Striatum; Female; gamma-Aminobutyric Acid; Glutamates; Ibotenic Acid; Mice; Neurons; Phencyclidine; Pregnancy; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Veratridine | 1989 |
Solubilisation and characterisation of a putative quisqualate-type glutamate receptor from chick brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Binding Sites; Binding, Competitive; Brain; Centrifugation, Density Gradient; Chickens; Chromatography; Detergents; Ibotenic Acid; Membranes; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Solubility | 1989 |
Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that beta-L-ODAP is a selective non-NMDA agonist.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Electrophysiology; Ibotenic Acid; Kainic Acid; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship; Synaptic Membranes | 1989 |
Antagonist profile of 6,7-dichloro-3-hydroxy-2-quinoxalinecarboxylate at excitatory amino acid receptors in the neonatal rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic Acid; Kainic Acid; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1989 |
Beta-N-oxalylamino-L-alanine action on glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Binding, Competitive; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Piperazines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synaptic Membranes; Thiocyanates | 1989 |
Two distinct quisqualate receptor systems are present on striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Ibotenic Acid; Inositol Phosphates; Mice; Oxadiazoles; Oxazoles; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter | 1989 |
Synaptic localization of striatal NMDA, quisqualate and kainate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Cerebral Decortication; Corpus Striatum; Glutamates; Histocytochemistry; Ibotenic Acid; Kainic Acid; Male; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cycloleucine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Transient increase in ligand binding to quisqualate and kainate sites in cerebral cortex of immature rats.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1989 |
Dissociation between changes in glutamate receptor binding sites and their coupling to phosphatidylinositol metabolism following intrahippocampal colchicine injection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Colchicine; Hippocampus; Ibotenic Acid; Male; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Second Messenger Systems | 1989 |
Excitatory amino acid receptors in the human cerebral cortex: a quantitative autoradiographic study comparing the distributions of [3H]TCP, [3H]glycine, L-[3H]glutamate, [3H]AMPA and [3H]kainic acid binding sites.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Female; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxazoles; Phencyclidine; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Pharmacological properties of quisqualate- and kainate-preferring glutamate receptors induced in Xenopus oocytes by rat and chick brain mRNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chickens; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1989 |
A voltage-clamp study of isolated stingray horizontal cell non-NMDA excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Separation; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fishes; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1989 |
A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dipeptides; Electric Stimulation; Female; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neural Conduction; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1989 |
Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; Quinoxalines; Rats; Synapses | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Hypoglycemia; Ibotenic Acid; Insulin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using L-[3H]glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Software; Tritium | 1989 |
A grease-gap method for studying the excitatory amino acid pharmacology of CA1 hippocampal pyramidal cells.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Female; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Inbred Strains; Valine | 1989 |
Is L-glutamate a neurotransmitter of baroreceptor information in the nucleus of the tractus solitarius?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Blood Pressure; Electric Stimulation; Female; Glutamates; Heart Rate; Ibotenic Acid; Kynurenic Acid; Medulla Oblongata; N-Methylaspartate; Neurotransmitter Agents; Pressoreceptors; Rats; Reflex; Sensory Receptor Cells; Xanthurenates | 1989 |
Non-NMDA glutamate receptor antagonist 3H-CNOX binds with equal affinity to two agonist states of quisqualate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Glutamates; Ibotenic Acid; In Vitro Techniques; Molecular Weight; Oxadiazoles; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Temperature | 1989 |
Early warning for LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Synapses; Time Factors | 1989 |
Two pharmacological classes of quisqualate-induced electrical responses in rat retinal ganglion cells in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Retina; Retinal Ganglion Cells | 1989 |
Excitation of hippocampal neurons by stimulation of glutamate Qp receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electric Stimulation; Electrophysiology; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Muscarinic; Receptors, Neurotransmitter | 1989 |
Displacement of excitatory amino acid receptor ligands by acidic oligopeptides.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Evidence for a single glutamate receptor of the ionotropic kainate/quisqualate type.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Protein Conformation; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Xenopus laevis | 1989 |
The pharmacology of quisqualate and AMPA in the cerebral cortex of the rat in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Neuromuscular Depolarizing Agents; Oxadiazoles; Oxazoles; Pentobarbital; Quisqualic Acid; Rats; Rats, Inbred Strains; Taurine | 1989 |
AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia innominata/lateral preoptic area.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Oxazoles; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Substantia Innominata | 1989 |
Neurochemical studies on quinolone antibiotics: effects on glutamate, GABA and adenosine systems in mammalian CNS.
Topics: 4-Quinolones; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Infective Agents; Aspartic Acid; Brain Chemistry; Calcium; Chlorides; Diazepam; gamma-Aminobutyric Acid; Glutamates; Ibotenic Acid; Kainic Acid; Male; Rats; Rats, Inbred Strains | 1989 |
Antagonism of responses to excitatory amino acids on rat cortical neurones by the spider toxin, argiotoxin636.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Indoleacetic Acids; Kainic Acid; Male; Membrane Potentials; Neurons; Phenylacetates; Polyamines; Rats; Rats, Inbred Strains | 1989 |
Complex structure of quisqualate-sensitive glutamate receptors in rat cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Ibotenic Acid; Molecular Weight; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter | 1985 |
Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Cats; Electrophoresis; Ibotenic Acid; In Vitro Techniques; Molecular Conformation; Neurons; Oxazoles; Quantum Theory; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Structure-Activity Relationship; Synaptic Membranes | 1985 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1985 |
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1986 |
Binding sites for [3H]glutamate and [3H]aspartate in human cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aspartic Acid; Binding Sites; Calcium Chloride; Cerebellum; Dicarboxylic Acids; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Oxadiazoles; Quisqualic Acid | 1986 |
Excitatory amino acid receptors and ischemic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kainic Acid; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1987 |
[3H]AMPA binding to glutamate receptor subpopulations in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain; Glutamates; Ibotenic Acid; Osmolar Concentration; Oxazoles; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Thiocyanates; Tritium | 1987 |
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Drug Interactions; Electrophysiology; Homocysteine; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Oxadiazoles; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Zinc | 1987 |
Characterization of quisqualate-type L-glutamate receptors in the retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Binding, Competitive; Chickens; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ibotenic Acid; Kinetics; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Subcellular Fractions | 1987 |
AMPA is a powerful neurotoxin in the chicken retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chickens; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Ibotenic Acid; Injections; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Oxadiazoles; Oxazoles; Quisqualic Acid; Retina; Retinal Ganglion Cells; Vitreous Body | 1987 |
Characterization of quisqualate recognition sites in rat brain tissue using DL-[3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) and a filtration assay.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chemical Phenomena; Chemistry; Filtration; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Thiocyanates | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Glutamate Decarboxylase; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Inhibition of [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Brain; Ibotenic Acid; In Vitro Techniques; Oxadiazoles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Membranes; Toxins, Biological | 1988 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
Rapid desensitization of glutamate receptors in vertebrate central neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Electric Conductivity; Hippocampus; Ibotenic Acid; In Vitro Techniques; Iontophoresis; Kynurenic Acid; N-Methylaspartate; Oxadiazoles; Pressure; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Time Factors | 1988 |
Characterization and regional distribution of glutamatergic and cholinergic ligand binding sites in goldfish brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Cyprinidae; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; Ligands; Ocular Physiological Phenomena; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1988 |
Chaotropic ions affect the conformation of quisqualate receptors in rat cortical membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cyanates; Cyanides; Ibotenic Acid; Kinetics; Membranes; Protein Conformation; Rats; Receptors, AMPA; Receptors, Drug | 1988 |
alpha-[3H]Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding to rat striatal membranes: effects of selective brain lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Denervation; Dopamine; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Ibotenic Acid; Membranes; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; Hippocampus; Ibotenic Acid; Kainic Acid; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1988 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Maturational changes in retinal excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Chick Embryo; Embryonic and Fetal Development; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1988 |
Effects of thiol-reagents on [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding to rat telencephalic membranes.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Sulfhydryl Reagents; Telencephalon | 1988 |
Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Female; Ibotenic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xenopus | 1988 |
Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Glutamates; Glutamine; Ibotenic Acid; Injections; Kainic Acid; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug | 1988 |
A glutamate receptor regulates Ca2+ mobilization in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Embryo, Mammalian; Glutamates; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Mice; Mice, Inbred C57BL; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Differences between seizure-prone and non-seizure-prone mice with regard to glutamate and GABA receptor binding in the hippocampus and other regions of the brain.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cerebral Cortex; Hippocampus; Ibotenic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Neurologic Mutants; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Seizures | 1987 |
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Chlorides; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Lithium; Lithium Chloride; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1988 |
Thiocyanate stabilizes AMPA binding to the quisqualate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Calcium; Chlorides; Coloring Agents; Glutamates; Ibotenic Acid; Ligands; Male; Oxadiazoles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Thiocyanates | 1988 |
Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Aspartic Acid; Basal Ganglia; Brain; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata; Synaptic Transmission | 1988 |
Glutamate receptors of ganglion cells in the rabbit retina: evidence for glutamate as a bipolar cell transmitter.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Light; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rabbits; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Retinal Ganglion Cells | 1988 |
Quantitative autoradiography of binding sites for [3H]AMPA, a structural analogue of glutamic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Ibotenic Acid; Male; Oxazoles; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Tissue Distribution; Tritium | 1984 |
Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Ibotenic Acid; Oxazoles; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter | 1984 |
The binding of [3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Female; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ibotenic Acid; Male; Mathematics; Oxazoles; Rats; Rats, Inbred Strains | 1982 |
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Ibotenic Acid; Interneurons; Oxazoles; Spinal Cord; Stereoisomerism; Synaptic Transmission; Valine | 1982 |
Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Oxazoles; Rats; Stereoisomerism | 1983 |
Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Stem; Cells, Cultured; Embryo, Mammalian; Glutamates; Ibotenic Acid; N-Methylaspartate; Oxazoles; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1983 |
The ionic mechanisms associated with the excitatory response of kainate, L-glutamate, quisqualate, ibotenate, AMPA and methyltetrahydrofolate on leech Retzius cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Ganglia; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Leeches; Membrane Potentials; Neurons; Osmolar Concentration; Oxadiazoles; Oxazoles; Pyrrolidines; Quisqualic Acid; Sodium; Tetrahydrofolates | 1984 |
(RS)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid: wet dog shakes, catalepsy and body temperature changes in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Catalepsy; Catecholamines; Humans; Hydroxyindoleacetic Acid; Ibotenic Acid; Male; Oxazoles; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Hyperactivity following injection of a glutamate agonist and 6,7-ADTN into rat nucleus accumbens and its inhibition by THIP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Humans; Hyperkinesis; Ibotenic Acid; Kinetics; Male; Motor Activity; Naphthalenes; Nucleus Accumbens; Oxazoles; Rats; Reserpine; Septal Nuclei; Tetrahydronaphthalenes | 1981 |
Effect of glutamic acid diethylester on (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and kainic acid-induced changes of body temperature in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Glutamates; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Oxazoles; Pyrrolidines; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Effects of nerve growth factor treatment on rats with lesions of the nucleus basalis magnocellularis produced by ibotenic acid, quisqualic acid, and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Ibotenic Acid; Immunohistochemistry; Male; Maze Learning; Nerve Growth Factors; Quisqualic Acid; Rats; Rats, Inbred F344; Substantia Innominata; Time Factors | 1995 |
Glutamate-evoked release of arachidonic acid from mouse brain astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurotoxins; Organ Specificity; Quisqualic Acid; Receptors, Glutamate; Time Factors; Tritium | 1994 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
Behavioral and biochemical consequences of combined lesions of the medial septum/diagonal band and nucleus basalis in the rat when ibotenic acid, quisqualic acid, and AMPA are used.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Avoidance Learning; Behavior, Animal; Biogenic Monoamines; Choline O-Acetyltransferase; Frontal Lobe; Ibotenic Acid; Male; Maze Learning; Neurotoxins; Prosencephalon; Quisqualic Acid; Rats; Rats, Inbred F344; Septum Pellucidum | 1994 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
AMPA-induced lesions of the basal forebrain differentially affect cholinergic and non-cholinergic neurons: lesion assessment using quantitative in situ hybridization histochemistry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Cholinergic Fibers; Gene Expression; Ibotenic Acid; In Situ Hybridization; Male; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA, Messenger | 1995 |
Excitatory amino acid receptor ligands: asymmetric synthesis, absolute stereochemistry and pharmacology of (R)- and (S)-homoibotenic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Radioligand Assay; Rats; Receptors, Glutamate; Stereoisomerism; Structure-Activity Relationship | 1995 |
Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
AMPA receptor activation potentiates zinc neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Drug Synergism; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Mice; Nervous System Diseases; Potassium; Receptors, AMPA; Receptors, Glutamate; Zinc | 1993 |
GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Synapses | 1993 |
Localisation of glutamate receptor binding sites and mRNAs to the dorsal horn of the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Neural Pathways; Phencyclidine; Rats; Receptors, Glutamate; RNA, Messenger; Spinal Cord; Substantia Gelatinosa | 1993 |
Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cerebral Cortex; Diuretics; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1993 |
NBQX inhibits AMPA-induced locomotion after injection into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Injections; Kainic Acid; Motor Activity; Nucleus Accumbens; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
N-methyl-D-aspartate- and non-N-methyl-D-aspartate-evoked adenosine release from rat cortical slices: distinct purinergic sources and mechanisms of release.
Topics: 5'-Nucleotidase; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Calcium; Cerebral Cortex; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Nucleosides; Purines; Rats | 1993 |
Cyclothiazide treatment unmasks AMPA excitotoxicity in rat primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Drug Synergism; Hippocampus; Ibotenic Acid; Kainic Acid; Neurotoxins; Rats | 1993 |
Dipsogenic effects of excitatory amino acid agonists in pigeons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Columbidae; Drinking; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1993 |
Binding of [3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and [3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cell Membrane; Dizocilpine Maleate; Female; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Receptors, Glutamate; Spermidine; Thiocyanates; Tissue Distribution | 1993 |
Actions of agonists of metabotropic glutamate receptors on synaptic transmission and transmitter release in the olfactory cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cycloleucine; Ibotenic Acid; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Olfactory Bulb; Potassium; Quinoxalines; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
Thiocyanate equally increases affinity for two DL-alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA) receptor states.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Thiocyanates | 1993 |
Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cycloleucine; Glycine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Phosphatidylinositols; Rats; Receptors, Glutamate; Spinal Cord; Thalamus | 1993 |
N-methyl-D-aspartate induces regular firing patterns in the cat lateral habenula in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Ibotenic Acid; Iontophoresis; Kainic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Stereotaxic Techniques; Thalamus | 1993 |
Norbinaltorphimine protection against N-methyl-D-aspartic acid-induced convulsions and mortality.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Binding, Competitive; Brain; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Naltrexone; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Calcium permeability of non-N-methyl-D-aspartate receptor channels in immature cerebellar Purkinje cells: studies using fura-2 microfluorometry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Cobalt; Cytophotometry; Fluorescent Dyes; Fura-2; Gallopamil; Ibotenic Acid; Kainic Acid; Manganese; Purkinje Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium | 1993 |
Mg2+ antagonizes alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced brain damage and convulsions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Ibotenic Acid; Magnesium; Male; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Cardiovascular sympathoinhibitory neurons form an extended longitudinal column in cat lateral medulla.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axonal Transport; Brain Mapping; Cardiovascular System; Cats; Female; Ibotenic Acid; Male; Medulla Oblongata; Microinjections; Neurons; Pressoreceptors; Reflex; Sympathetic Nervous System; Vagotomy | 1993 |
Enflurane inhibits NMDA, AMPA, and kainate-induced currents in Xenopus oocytes expressing mouse and human brain mRNA.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Enflurane; Female; Humans; Ibotenic Acid; Ion Channels; Kainic Acid; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Oocytes; Receptors, Glutamate; RNA, Messenger; Species Specificity; Xenopus laevis | 1993 |
Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus of the tractus solitarius of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Medulla Oblongata; Muscimol; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses | 1993 |
Single channel recordings of reconstituted AMPA receptors reveal low and high conductance states.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Electric Conductivity; Ibotenic Acid; Ion Channels; Kainic Acid; Lipid Bilayers; Prosencephalon; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Regression Analysis | 1993 |
(R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors mediate a calcium-dependent inhibition of the metabotropic glutamate receptor-stimulated formation of inositol 1,4,5-trisphosphate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol 1,4,5-Trisphosphate; N-Methylaspartate; Protein Kinases; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Glutamate dehydrogenase improves binding of [3H]CGP39653 to NMDA receptors in the autoradiographic assay.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Neurotransmitter receptors and voltage-dependent Ca2+ channels encoded by mRNA from the adult corpus callosum.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antisense Elements (Genetics); Aspartic Acid; Astrocytes; Biomarkers; Calcium Channels; Cattle; Corpus Callosum; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Male; Membrane Potentials; Middle Aged; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA Probes; RNA, Messenger; Xenopus | 1993 |
Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Glutamate stimulates [3H]phorbol 12,13-dibutyrate binding in cultured Bergmann glia cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cells, Cultured; Cerebellum; Chick Embryo; Cytosol; Enzyme Activation; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neuroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purkinje Cells | 1993 |
Expression of AMPA-selective glutamate receptor subunits in morphologically defined neurons of the mammalian cochlear nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Cochlear Nerve; Granulocytes; Ibotenic Acid; In Situ Hybridization; Neurons; Rats; Receptors, Glutamate; RNA, Messenger; Silver; Tissue Distribution | 1993 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Attenuation of AMPA-induced neurotoxicity by a calpain inhibitor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Calpain; Cerebellum; Dipeptides; Female; Ibotenic Acid; Molecular Sequence Data; Nervous System Diseases; Pregnancy; Purkinje Cells; Rats; Rats, Sprague-Dawley | 1993 |
Non-NMDA-mediated transmission of somatosensory-evoked potentials in the rat thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Anticonvulsants; Electric Stimulation; Evoked Potentials, Somatosensory; Glycine; Ibotenic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Somatosensory Cortex; Stereotaxic Techniques; Synaptic Transmission; Thalamic Nuclei | 1993 |
Properties of [3H]AMPA binding in postmortem human brain from psychotic subjects and controls: increases in caudate nucleus associated with suicide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Cadaver; Caudate Nucleus; Female; Freezing; Humans; Ibotenic Acid; Male; Schizophrenia; Sex Characteristics; Suicide; Tritium | 1993 |
Are chimeric kainate/N-methyl-D-aspartate receptors expressed in Xenopus oocytes from mammalian and amphibian RNA?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Female; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oocytes; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; RNA; Xenopus | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Electrophysiological evidence for the existence of NMDA and non-NMDA receptors on rat ventral tegmental dopamine neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 1993 |
Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electrophysiology; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
The AMPA receptor antagonist NBQX does not alter the motor response induced by selective dopamine agonists in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine Agents; Excitatory Amino Acid Antagonists; Ibotenic Acid; Indoles; Macaca fascicularis; Motor Activity; Oxazines; Parkinson Disease; Phenanthridines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate | 1993 |
Direct evidence for axonal outgrowth from cholinergic grafts to cholinergically-deafferented rat cortex.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Basal Ganglia; Benzofurans; Brain Tissue Transplantation; Cerebral Cortex; Fetal Tissue Transplantation; Fluorescent Dyes; Frontal Lobe; Histocytochemistry; Ibotenic Acid; Male; Neurons, Afferent; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley | 1993 |
Effects of phencyclidine on spontaneous and excitatory amino acid-induced activity of ventral tegmental dopamine neurons: an extracellular in vitro study.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dopamine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neurons; Phencyclidine; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 1993 |
Behavioral parameters of the spatial memory correlate with the potentiation of the population spike, but not with the population excitatory postsynaptic potential, of the CA1 region in rat hippocampal slices.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Tissue Transplantation; Escape Reaction; Fetal Tissue Transplantation; Hippocampus; Ibotenic Acid; Male; Memory; Memory, Short-Term; Rats; Rats, Sprague-Dawley; Reaction Time; Septum Pellucidum; Spatial Behavior | 1993 |
Medium-dependent dissociation of cytotoxic and GABA-releasing effects of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and kainate in rat cortical cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1993 |
Transsynaptic induction of c-fos in basal forebrain, diencephalic and midbrain neurons following AMPA-induced activation of the dorsal and ventral striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Choline O-Acetyltransferase; Corpus Striatum; Diencephalon; Fluorescent Dyes; Genes, fos; Globus Pallidus; Ibotenic Acid; Immunohistochemistry; Male; Mesencephalon; Neurons; Prosencephalon; Rats; Stilbamidines; Synapses | 1993 |
Differential activation and survival of basal forebrain neurons following infusions of excitatory amino acids: studies with the immediate early gene c-fos.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Survival; Choline O-Acetyltransferase; Corpus Striatum; Genes, fos; Globus Pallidus; Ibotenic Acid; Immunohistochemistry; Male; Neurons; Phosphates; Prosencephalon; Quisqualic Acid; Rats | 1993 |
The role of amino acid neurotransmitters in the descending control of electroreception.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Bicuculline; Dendrites; Electric Stimulation; Electrophysiology; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Microinjections; Neurons; Neurotransmitter Agents; Pyramidal Tracts; Quinoxalines; Sensory Receptor Cells | 1993 |
Stimulation by glutamate receptors of arachidonic acid release depends on the Na+/Ca2+ exchanger in neuronal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Calcium; Carrier Proteins; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Ibotenic Acid; Mice; N-Methylaspartate; Neurons; Phospholipases A; Phospholipases A2; Protein Kinase C; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Calcium Exchanger; Veratridine; Virulence Factors, Bordetella | 1993 |
The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Base Sequence; Cells, Cultured; Embryo, Mammalian; Hippocampus; Ibotenic Acid; Immunohistochemistry; In Situ Hybridization; Macromolecular Substances; Molecular Sequence Data; Neurons; Oligodeoxyribonucleotides; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Synapses | 1993 |
Induction of astrocyte glutamine synthetase activity by the Lathyrus toxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (beta-L-ODAP).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Animals, Newborn; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Glutamate-Ammonia Ligase; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carrier Proteins; Cerebral Cortex; Citalopram; Hippocampus; Ibotenic Acid; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Endings; Nerve Tissue Proteins; Parasympathetic Nervous System; Prosencephalon; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Quantitative localization of AMPA/kainate and kainate glutamate receptor subunit immunoreactivity in neurochemically identified subpopulations of neurons in the prefrontal cortex of the macaque monkey.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Antibodies; Biomarkers; Epitopes; Humans; Ibotenic Acid; Immunohistochemistry; Kainic Acid; Macaca fascicularis; Macromolecular Substances; Nerve Tissue Proteins; Neurons; Prefrontal Cortex; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Characterization of the metabotropic glutamate receptor in mouse cerebellar granule cells: lack of effect of 2,3-dihydroxy-6-nitro-7-sulphamoylbenzo(F)-quinoxaline (NBQX).
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Mice; Neurons; Pertussis Toxin; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Virulence Factors, Bordetella | 1993 |
(2s,1'R,2'R,3'R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cycloleucine; Cyclopropanes; Glycine; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Reconstitution of glutamate receptor proteins purified from Xenopus central nervous system into artificial bilayers.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chromatography, Affinity; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Lipid Bilayers; N-Methylaspartate; Receptors, Glutamate; Xenopus | 1993 |
Ionotropic non-N-methyl-D-aspartate agonists induce retraction of dendritic spinules from retinal horizontal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Carps; Cell Movement; Cyclopentanes; Dendrites; Ibotenic Acid; N-Methylaspartate; Quisqualic Acid; Receptors, Neurotransmitter; Retina | 1993 |
NMDA receptors mediate neuronal burst firing in rat somatosensory cortex in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex | 1993 |
A novel mechanism of AMPA receptor regulation: ionically triggered kinases and phosphatases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chlorides; Glycerophosphates; Ibotenic Acid; In Vitro Techniques; Isoquinolines; Peptides; Phosphoric Monoester Hydrolases; Piperazines; Potassium; Protein Kinase Inhibitors; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Sodium; Tamoxifen; Vanadates | 1993 |
Lateral hypothalamic injections of glutamate, kainic acid, D,L-alpha-amino-3-hydroxy-5-methyl-isoxazole propionic acid or N-methyl-D-aspartic acid rapidly elicit intense transient eating in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Eating; Glutamates; Glutamic Acid; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Kainate toxicity in energy-compromised rat hippocampal slices: differences between oxygen and glucose deprivation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Electrophysiology; Energy Metabolism; Evoked Potentials; Glucose; Hippocampus; Hypoxia, Brain; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Identification of glutamate receptor subtypes mediating inputs to bipolar cells and ganglion cells in the tiger salamander retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Aminobutyrates; Animals; Glutamates; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Photic Stimulation; Piperazines; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Synapses | 1993 |
AMPA and NMDA binding sites in the hypothalamic lateral tuberal nucleus: implications for Huntington's disease.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 1993 |
An analysis of synaptic transmission to motoneurones in the cat spinal cord using a new selective receptor blocker.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cats; Electrophysiology; Female; Ibotenic Acid; Male; Motor Neurons; N-Methylaspartate; Spinal Cord; Synapses; Synaptic Transmission | 1993 |
Photostimulation using caged glutamate reveals functional circuitry in living brain slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cats; Evoked Potentials; Ferrets; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Somatosensory Cortex; Synapses; Tetrodotoxin; Ultraviolet Rays; Visual Cortex | 1993 |
N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Conotoxins; Dendrites; Evoked Potentials; Ibotenic Acid; Magnesium; Membrane Potentials; Mollusk Venoms; N-Methylaspartate; Neurons; Peptides, Cyclic; Pyramidal Tracts; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Anion transport blockers inhibit DL-2-amino-4-phosphonobutyrate responses induced by quisqualate in the rat cerebral cortex.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate | 1993 |
Thiocyanate ions selectively antagonize AMPA-evoked responses in Xenopus laevis oocytes microinjected with rat brain mRNA.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Cell Membrane; Cerebellum; Electrophysiology; Female; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Microinjections; Neurons; Oocytes; Pregnancy; Pyrimidinones; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Thiocyanates; Uracil; Xenopus laevis | 1993 |
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gerbillinae; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kinetics; Male; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glucagon; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Islets of Langerhans; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Ibotenic Acid; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Spinal Cord; Stereoisomerism; Thalamus | 1993 |
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Ketamine; Male; Neurons; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Excitatory amino acid-induced slow biphasic responses of free intracellular calcium in human neuroblastoma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cycloleucine; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Tumor Cells, Cultured | 1993 |
Non-NMDA receptors in the rostral ventrolateral medulla mediate somatosympathetic pressor responses.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Blood Pressure; Electric Stimulation; Female; Histocytochemistry; Ibotenic Acid; Kainic Acid; Medulla Oblongata; Neurons, Afferent; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Sympathetic Nervous System; Vagotomy | 1993 |
Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Evoked Potentials; Glucose; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pipecolic Acids; Pyramidal Tracts; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tritium | 1993 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Spinal Cord | 1993 |
Differential modulation by cyclothiazide and concanavalin A of desensitization at native alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Ganglia, Spinal; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Neurons; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Two distinct types of AMPA responses in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Hippocampus; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; Neurons; Pyrrolidinones; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Pentamidine, an inhibitor of spinal flexor reflexes in rats, is a potent N-methyl-D-aspartate (NMDA) antagonist in vivo.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Drug Interactions; Electromyography; H-Reflex; Ibotenic Acid; Injections, Spinal; Male; N-Methylaspartate; Pentamidine; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Stretch; Tibial Nerve | 1993 |
Discriminable excitotoxic effects of ibotenic acid, AMPA, NMDA and quinolinic acid in the rat laterodorsal tegmental nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics; Animals; Drug Evaluation, Preclinical; Ethanol; Excitatory Amino Acid Agonists; Ibotenic Acid; Locus Coeruleus; Male; N-Methylaspartate; Neurotoxins; Pentobarbital; Pons; Quinolinic Acid; Raphe Nuclei; Rats; Tegmentum Mesencephali | 1997 |
The cerebral metabolic effects of manipulating glutamatergic systems within the basal forebrain in conscious rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Blood Glucose; Body Temperature; Brain Chemistry; Excitatory Amino Acid Agonists; Glucose; Glutamic Acid; Hemodynamics; Ibotenic Acid; Isoquinolines; Male; Prosencephalon; Rats; Stereotaxic Techniques | 1998 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ibotenic Acid; Insecta; Protein Binding; Protein Subunits; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Stereoisomerism; Structure-Activity Relationship; Transfection; Tritium | 2005 |