alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with gyki 53655 in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (56.25) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| England, PM; Fleming, JJ | 1 |
| Chizh, BA; Cumberbatch, MJ; Headley, PM | 2 |
| Burnett, JP; Desai, MA; Ornstein, PL; Schoepp, DD | 1 |
| Lodge, D; Palmer, AJ | 1 |
| Parks, TN; Taylor, DA; Zhou, N | 1 |
| Borsini, F; Brambilla, A; Grippa, N; Prudentino, A | 1 |
| Kombian, SB; Pittman, QJ; Saleh, TM; Zidichouski, JA | 1 |
| Ballyk, BA; Bath, CP; Bleakman, D; Bufton, HR; Kamboj, RK; Lodge, D; Palmer, AJ; Schoepp, DD; Sharpe, EF; Tarnawa, I; Woolley, ML | 1 |
| Kovács, AD; Szabó, G | 1 |
| Bleakman, D; Bristow, DR; Savidge, JR | 1 |
| Barks, JD; Liu, XH; Wang, P | 1 |
| Bureau, I; Mulle, C | 1 |
| Lu, T; Shen, Y; Yang, XL | 1 |
| Carvalho, AP; Duarte, CB; Ferreira, IL | 1 |
| Dai, WM; Ebert, B; Lambert, JD; Madsen, U | 1 |
| Geurtz, W; Hatt, H; Okada, T; Schultz, K; Weiler, R | 1 |
| Bristow, DR; Lock, EA; Savidge, JR; Sturgess, NC | 1 |
| Perkinton, MS; Sihra, TS; Williams, RJ | 1 |
| Lerma, J; López-García, JC; Rodríguez-Moreno, A | 1 |
| Durand, J; Ruiz, A | 1 |
| Cebers, G; Kovács, AD; Liljequist, S | 1 |
| Closier, M; Iop, F; Lestage, P; Lockhart, B | 1 |
| Brorson, JR; Ihle, EC; Patneau, DK; Robberecht, W; Vandenberghe, W | 1 |
| Baumbarger, PJ; Muhlhauser, M; Nisenbaum, ES; Yang, CR; Zhai, J | 1 |
| Christensen, KV; Dai, WM; Ebert, B; Egebjerg, J; Lambert, JD | 1 |
| Alberdi, E; Marino, A; Matute, C; Sánchez-Gómez, MV | 1 |
| Allgaier, C; Fischer, W; Franke, H; Illes, P; Scheibler, P | 1 |
| Hartveit, E; Mørkve, SH; Veruki, ML | 1 |
| Arai, AC; Kessler, M | 1 |
| Anderson, RL; Daniele, C; Engelman, HS; Macdermott, AB | 1 |
| Kimura, H; Kunugi, A; Suzuki, A; Tajima, Y | 1 |
32 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and gyki 53655
| Article | Year |
|---|---|
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA | 2010 |
AMPA receptors have an equal role in spinal nociceptive and non-nociceptive transmission.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Iontophoresis; Male; N-Methylaspartate; Nociceptors; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Synaptic Transmission | 1994 |
A comparison of intravenous NBQX and GYKI 53655 as AMPA antagonists in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Hot Temperature; Injections, Intravenous; Iontophoresis; Male; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord | 1994 |
Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Binding Sites; Binding, Competitive; Hippocampus; In Vitro Techniques; Isoquinolines; Kainic Acid; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles | 1995 |
Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cerebral Cortex; Diuretics; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1993 |
Cobalt-permeable non-NMDA receptors in developing chick brainstem auditory nuclei.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Benzodiazepines; Brain Stem; Cell Membrane Permeability; Chick Embryo; Cobalt; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Neurons; Receptors, N-Methyl-D-Aspartate | 1995 |
Pharmacological characterization of AMPA-induced biting behaviour in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Cholecystokinin and neurotensin inversely modulate excitatory synaptic transmission in the parabrachial nucleus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cholecystokinin; Devazepide; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hormone Antagonists; Interneurons; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Neurotensin; Patch-Clamp Techniques; Phenylurea Compounds; Pons; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin | 1997 |
Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Humans; Kidney; Membrane Potentials; Molecular Structure; Neurons; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recombinant Proteins; Spinal Cord; Structure-Activity Relationship; Transfection | 1996 |
GYKI 53665, a 2,3-benzodiazepine, non-competitively protects cultured neurones against AMPA toxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Neuroprotective Agents; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Identification of kainate receptor-mediated intracellular calcium increases in cultured rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Calcium; Cells, Cultured; Cerebellum; Concanavalin A; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Intracellular Membranes; Isoquinolines; Kainic Acid; Neurons; Rats; Receptors, Kainic Acid; Tetrazoles | 1997 |
The non-competitive AMPA antagonist LY 300168 (GYKI 53655) attenuates AMPA-induced hippocampal injury in neonatal rodents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Atrophy; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Injections, Intraperitoneal; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1997 |
Potentiation of GABAergic synaptic transmission by AMPA receptors in mouse cerebellar stellate cells: changes during development.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cadmium; Cerebellum; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mice; Neural Inhibition; Neuromuscular Depolarizing Agents; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Transmission; Tetrodotoxin | 1998 |
Desensitization of AMPA receptors on horizontal cells isolated from crucian carp retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; Kainic Acid; Patch-Clamp Techniques; Receptors, AMPA; Retina | 1998 |
Kainate-induced retina amacrine-like cell damage is mediated by AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium Radioisotopes; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Neuromuscular Depolarizing Agents; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1998 |
Studies of the antagonist actions of (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl] propionic acid (ATPO) on non-NMDA receptors in cultured rat neurones.
Topics: Adrenal Cortex Hormones; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Isoxazoles; Kainic Acid; Neurons; Organophosphonates; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1998 |
AMPA-preferring receptors with high Ca2+ permeability mediate dendritic plasticity of retinal horizontal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carps; Dark Adaptation; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Membrane Potentials; Microscopy, Electron; Neuronal Plasticity; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1999 |
Characterisation of kainate receptor mediated whole-cell currents in rat cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Concanavalin A; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Kinetics; Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Receptors, Kainic Acid; Spider Venoms | 1999 |
Ca(2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase signaling cascade in neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Arachidonic Acid; Benzodiazepines; Benzothiadiazines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Genistein; GTP-Binding Proteins; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptors, AMPA; Signal Transduction; Virulence Factors, Bordetella; Wortmannin | 1999 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Blocking the trigeminal EPSP in rat abducens motoneurons in vivo with the AMPA antagonists NBQX and GYKI 53655.
Topics: Abducens Nerve; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Male; Motor Neurons; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Trigeminal Nerve | 2000 |
Kainate receptor-mediated activation of the AP-1 transcription factor complex in cultured rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Cerebellum; Concanavalin A; Dimerization; Excitatory Amino Acid Antagonists; Isoquinolines; Kainic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tetrazoles; Transcription Factor AP-1 | 2000 |
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium | 2000 |
AMPA receptor current density, not desensitization, predicts selective motoneuron vulnerability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Posterior Horn Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2000 |
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides | 2001 |
Correlation of the expression of kainate receptor subtypes to responses evoked in cultured cortical and spinal cord neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Concanavalin A; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2002 |
Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Lanthanum; Neurotoxins; Nifedipine; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 2002 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Functional characteristics of non-NMDA-type ionotropic glutamate receptor channels in AII amacrine cells in rat retina.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Concanavalin A; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Membrane Potentials; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, Glutamate; Retina; Sodium | 2002 |
Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Allosteric Site; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Membranes; Peptides, Cyclic; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tritium | 2006 |
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors modulate release of inhibitory amino acids in rat spinal cord dorsal horn.
Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzodiazepines; Cadmium Chloride; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kainic Acid; Neural Inhibition; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Receptors, AMPA; Receptors, Presynaptic; Spinal Cord | 2006 |
Electrophysiological characterization of a novel AMPA receptor potentiator, TAK-137, in rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Thiadiazines | 2019 |