alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with glutamic acid in 662 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (3.47) | 18.7374 |
| 1990's | 291 (43.96) | 18.2507 |
| 2000's | 232 (35.05) | 29.6817 |
| 2010's | 80 (12.08) | 24.3611 |
| 2020's | 36 (5.44) | 2.80 |
| Authors | Studies |
|---|---|
| Honoré, T; Krogsgaard-Larsen, P; Lauridsen, J | 2 |
| Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Nielsen, E | 1 |
| Bräuner-Osborne, H; Ebert, B; Krogsgaard-Larsen, P; Nakanishi, S; Sekiyama, N; Skjaerbaek, N; Sløk, FA | 1 |
| Bleakman, D; Deverill, M; Hoo, K; Jane, DE; Kamboj, R; Mandelzys, A | 1 |
| Danthi, SN; Hill, RA; Layer, RT; Miller, DD; Shams, G; Tai, H; Uretsky, NJ; Wallace, LJ; Weinstein, DM; Willins, D | 1 |
| Bräuner-Osborne, H; Conti, P; De Amici, M; De Micheli, C; De Sarro, G; Madsen, U; Rizzo, M; Stensbøl, TB; Toma, L | 1 |
| Armstrong, N; Gouaux, E | 1 |
| Alt, A; Bleakman, D; Bortolotto, ZA; Collingridge, GL; Dolman, NP; Jack, S; Jane, DE; Knauss, JL; More, JC; Morley, RM; Nistico, R; Roberts, PJ; Troop, HM | 1 |
| Barinka, C; Hlouchová, K; Konvalinka, J; Lubkowski, J; Majer, P; Mlcochová, P; Plechanovová, A; Rovenská, M; Slusher, BS; Tsukamoto, T | 1 |
| Bräuner-Osborne, H; Brehm, L; Clausen, RP; Gajhede, M; Geneser, U; Greenwood, JR; Jensen, AA; Kastrup, JS; Kristensen, AS; Krogsgaard-Larsen, P; Naur, P; Nielsen, AS; Nielsen, B; Pickering, DS; Ringgaard, LM; Strange, M | 1 |
| Boschi, D; Clausen, RP; Farnsworth, JC; Hansen, KB; Jensen, AA; Kastrup, JS; Lolli, ML; Møllerud, S; Nielsen, B; Passoni, A; Pickering, DS; Sainas, S; Temperini, P; Yi, F | 1 |
| Madsen, U; Wong, EH | 1 |
| Ohfune, Y; Shimamoto, K | 1 |
| Didriksen, M; Ebert, B; Engesgaard, A; Frølund, B; Jaroszewski, JW; Krogsgaard-Larsen, P; Matzen, L | 1 |
| Araldi, GL; Kozikowski, AP; Pshenichkin, S; Steensma, D; Surina, E; Tückmantel, W; Wang, S; Wroblewski, JT | 1 |
| Butini, S; Campiani, G; Christensen, JK; Coccone, SS; De Angelis, M; Fiorini, I; Gemma, S; Guarino, E; Morelli, E; Novellino, E; Pickering, DS; Schousboe, A; Trotta, F | 1 |
| England, PM; Fleming, JJ | 1 |
| Amir, A; Contreras-Sanz, A; Foti, A; Fruttero, R; Gasco, A; Giordano, C; Hansen, KB; Johansen, TN; Lolli, ML; Nielsen, B; Pickering, DS; Rolando, B | 1 |
| Cox, JA; Seeburg, PH; Stein, E; Verdoorn, TA | 1 |
| Ozawa, S; Takeuchi, T; Tsuzuki, K | 1 |
| Jonas, P; Sakmann, B | 1 |
| Maruyama, M; Nakazawa, M; Takeda, K | 1 |
| Barnes, CA; Foster, TC; McNaughton, BL; Rao, G | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Clark, B; Mobbs, P | 1 |
| Andersen, CF; Frandsen, A; Schousboe, A | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Yamada, S; Yoshimura, M | 1 |
| Fain, GL; Yazejian, B | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Martin, D; McNamara, JO; Nadler, JV | 1 |
| Cha, JH; Davis, RE; Wilmot, GR | 1 |
| Kawai, N; Nakajima, T; Robinson, HP; Shimazaki, K; Takenawa, T | 1 |
| Balázs, R; Hack, N; Kumar, KN; Michaelis, E; Resink, A; Van der Valk, JB | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 2 |
| Parks, TN; Zhou, N | 1 |
| Bleakman, D; Chard, PS; Glaum, SR; Miller, RJ; Rusin, KI | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 2 |
| Bonhaus, DW; McNamara, JO | 1 |
| Blazynski, C; Linn, DM; Massey, SC; Redburn, DA | 1 |
| Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Mayer, ML; Patneau, DK | 1 |
| Dodd, PR; Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Shreve, PE; Uretsky, NJ | 1 |
| Connor, JA; Dickinson, MH; Linden, DJ; Smeyne, M | 1 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| MacVicar, BA; Tse, FW; Weiss, S | 1 |
| Chang, YC; Lee, YH; Leng, CH; Lin, YH | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Garthwaite, J; Southam, E | 1 |
| Hu, GY; Storm, JF | 1 |
| Cai, NS; Erdö, SL; Kiss, B | 1 |
| Hećimović, H; Randić, M; Ryu, PD | 1 |
| Mayer, ML | 1 |
| Audinat, E; Crepel, F; Geoffroy, M; Hamon, B; Kado, RT; Lambolez, B; Rossier, J | 1 |
| Amaya, Y; Hattori, S; Kawamoto, S; Mishina, M; Miyagi, Y; Okuda, K; Onishi, H | 1 |
| Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A | 1 |
| Cha, JH; Drejer, J; Honoré, T; Nielsen, EO; Young, AB | 1 |
| Gelhard, RE; Insel, TR; Miller, LP | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Butterworth, RF; Cotman, CW; Giguere, JF; Peterson, C | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Burgoyne, RD; Cambray-Deakin, MA; Foster, AC | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA | 1 |
| Albin, RL; Cha, JH; Gilman, S; Makowiec, RL; Young, AB | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Boos, R; Müller, F; Wässle, H | 1 |
| Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J; Shand, A | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Christensen, BN; O'Dell, TJ | 1 |
| O'Dell, TJ | 1 |
| Westerberg, E; Wieloch, TW | 1 |
| Beart, PM; Cincotta, M; Summers, RJ | 1 |
| Anwyl, R | 1 |
| Gulyás, J; Janáky, R; Kontro, P; Marnela, KM; Oja, SS; Varga, V | 1 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Cotman, CW; Monaghan, DT; Yao, D | 1 |
| Cotman, CW; Ganong, AH | 1 |
| Cross, A; Skan, W; Slater, P | 1 |
| López-Colomé, AM; Somohano, F | 1 |
| Murphy, DE; Snowhill, EW; Williams, M | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Henley, JM; Oswald, RE | 1 |
| Errami, M; Nieoullon, A | 1 |
| López-Colomé, AM; Roberts, PJ; Somohano, F | 1 |
| Curtis, DR; Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Leah, JD; Peet, MJ | 1 |
| Kerkut, GA; Mat Jais, AM; Walker, RJ | 1 |
| Kawai, N; Masuzawa, T; Nakaima, T; Oguro, K; Tsubokawa, H | 1 |
| Baker, RC; Winter, CR | 1 |
| Barbeito, L; Estevez, AG; Stutzmann, JM | 1 |
| Brown, CS; Chen, Q; Harris, C; Howe, A; Reiner, A; Surmeier, DJ | 1 |
| Botscheller, ML; DeKosky, ST; Marion, DW; Palmer, AM; Styren, SD; Swedlow, PE | 1 |
| Buchhalter, JR; Djali, S; Robinson, MB | 1 |
| Henschke, G; Wolf, G; Würdig, S | 1 |
| Bullock, S; Pearce, B; Potter, J; Rose, SP | 1 |
| MacDermott, AB; Reichling, DB | 1 |
| Miller, RF; Thoreson, WB | 1 |
| Cheng, B; Christakos, S; Mattson, MP | 1 |
| Glowinski, J; Prémont, J; Stella, N; Tencé, M | 1 |
| Konnerth, A; Schneggenburger, R; Tempia, F | 1 |
| Donias, HW; Ha, LH; Spears, LC; Stanley, BG; Willett, VL | 1 |
| Soderling, TR; Tan, SE; Wenthold, RJ | 1 |
| Kaneko, S; Nakamura, S; Satoh, M | 1 |
| Johnston, MV; Supko, DE | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R; Tribillac, F | 1 |
| Chiodo, LA; Freeman, AS; Zhang, J | 1 |
| Chen, SC; Deupree, DL; Kao, LS; Lee, YH; Wu, JY | 1 |
| Bowie, D; Smart, TG | 1 |
| Keinänen, K; Köhr, G; Laukkanen, ML; Oker-Blom, C; Seeburg, PH | 1 |
| Brose, N; Egebjerg, J; Kukekov, V; Lin, F; Louis, JC; Moran, T; Puchalski, RB; Rogers, SW; Traynelis, SF; Wenthold, RJ | 1 |
| Akaike, A; Kimura, J; Shimohama, S; Tamura, Y; Yokota, T | 1 |
| Herrera, AJ; Osborne, NN | 1 |
| Hatt, H; Kruse, M; Schmidt, KF | 1 |
| Amico, C; Condorelli, DF; Dell'Albani, P; Giuffrida-Stella, AM; Kaczmarek, L; Lukasiuk, K | 1 |
| Wu, C | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Adler-Graschinsky, E; Butta, NV; Lorenzo, PS | 1 |
| Bruno, VM; Choi, DW; Dugan, LL; Giffard, RG; Goldberg, MP | 1 |
| Binns, KE; Do, KQ; Salt, TE | 1 |
| Buchwald, NA; Cepeda, C; Levine, MS; Peacock, W; Radisavljevic, Z | 1 |
| Dekermendjian, K; Frandsen, A; Nielsen, M; Schousboe, A; Witt, MR | 1 |
| Albert, A; Bonhomme, V; Collette, J; Hans, P; Moonen, G | 1 |
| Greenamyre, JT; Greene, JG | 2 |
| Kasparov, S; Pawelzik, H; Zieglgänsberger, W | 1 |
| Barnes, JM; Dev, KK; Henley, JM | 1 |
| Collins, DR; Davies, SN | 1 |
| Büsselberg, D; Haas, H; Platt, B | 1 |
| Oja, SS; Saransaari, P | 1 |
| Obrenovitch, TP; Urenjak, J; Zilkha, E | 1 |
| Carvalho, AP; Carvalho, CM; Malva, JO | 2 |
| Greenamyre, JT; Porter, RH | 1 |
| Chen, JC; Chesler, M; Gottfried, JA; Smith, SE | 1 |
| Devillers, JP; Simonnet, G | 1 |
| Fattman, CL; Hoyt, KR; Rajdev, S; Reynolds, IJ | 1 |
| Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Rothwell, NJ; Strijbos, PJ | 1 |
| Dowling, JE; Grant, GB | 1 |
| Hatt, H; Jensen, P; Lowe, D; Smith, DO; Temkin, R | 1 |
| Grinspan, JB; Hardy, M; Pleasure, D; Stern, JL; Yoshioka, A; Younkin, DP | 1 |
| Acciarri, N; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Ferraro, L; Morari, M; Piazza, G | 1 |
| Brorson, JR; Gibbons, SJ; Manzolillo, PA; Miller, RJ | 1 |
| Amagasu, SM; Bruno, VM; Dugan, LL; Giffard, RG | 1 |
| Park, J; Tasker, RC; Vornov, JJ | 1 |
| Gean, PW; Huang, CC; Wang, SJ | 1 |
| Inoue, H; Koizumi, S; Ochi, M; Shibata, S; Watanabe, S | 1 |
| Akaike, A; Kaneko, S; Maeda, T; Mizukami, K; Satoh, M; Shimohama, S; Shimoshige, Y | 1 |
| Bischoff, F; Ebert, B; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| McCarthy, KD; Porter, JT | 1 |
| Arai, A; Kessler, M; Lynch, G; Silberg, J | 1 |
| Geiger, JR; Jonas, P; Koh, DS; Sakmann, B | 1 |
| Henley, JM | 1 |
| Christoffersen, CL; Meltzer, LT | 1 |
| Hill, JM; Kaufman, MP; Wong, MK | 1 |
| LeDoux, JE; Li, XF; Phillips, R | 1 |
| Cheng, B; Fabian, T; Furukawa, K; Goodman, Y; Kihiko, M; Mattson, MP; O'Keefe, JA | 1 |
| Catania, MV; Hollingsworth, Z; Penney, JB; Young, AB | 2 |
| Henley, JM; Hunt, SP; Jenkins, R | 1 |
| Andou, Y; Enomoto, R; Kataoka, K; Mitani, A; Ogita, K; Yoneda, Y | 1 |
| Baudry, M; Hall, RA; Kessler, M; Lynch, G; Massicotte, G | 1 |
| Glaum, SR; Miller, RJ | 1 |
| Alagarsamy, S; Johnson, KM; Lonart, G | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 1 |
| Matute, C; Miledi, R | 1 |
| Cid, ME; Ortega, A | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Bastian, J | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Mayer, ML; Patneau, DK; Vyklicky, L | 1 |
| Dee, MG; Ha, LH; Spears, LC; Stanley, BG | 1 |
| Albin, RL; Kremer, B; Tallaksen-Greene, SJ | 1 |
| Naarala, J; Nykvist, P; Savolainen, K; Tuomala, M | 1 |
| Barrionuevo, G; Fleck, MW; Henze, DA; Palmer, AM | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Chiu, SY; Kriegler, S | 1 |
| Klockgether, T; Turski, L | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Francois-Bellan, AM; Giraud, P; Hery, F; Hery, M | 1 |
| Clements, JD; Oleskevich, S; Williams, JT | 1 |
| De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Maura, G; Raiteri, M | 1 |
| Gallo, V; Holtzclaw, LA; Russell, JT | 1 |
| Böing, C; Fink, K; Göthert, M; Schmitz, V | 1 |
| Benz, AM; Izumi, Y; Kurby, CO; Labruyere, J; Olney, JW; Price, MT; Zorumski, CF | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Elliott, CE; Fletcher, EJ; Hoo, KH; Kamboj, RK; Korczak, B; McWhinnie, EA; Nutt, SL | 1 |
| Ben-Ari, Y; Congar, P; Khazipov, R | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Friedemann, MN; Gerhardt, GA | 1 |
| Cebers, G; Kalda, A; Liljequist, S | 1 |
| Gilbert, E; Grimwood, S; Hutson, PH; Ragan, CI | 1 |
| Brann, DW; Mahesh, VB; Zamorano, PL; Zuo, Z | 1 |
| Bristow, DR; Platt, KP | 1 |
| Ebling, FJ; Hastings, MH; Hui, Y; Maywood, ES; Mirakhur, A | 1 |
| Chiba, C; Saito, T | 1 |
| Kaneko, A; Sasaki, T | 1 |
| Carvalho, AP; Duarte, CB; Sánchez-Prieto, J; Santos, PF | 1 |
| Araujo, M; Wandosell, F | 1 |
| Blosser, J; Buchan, A; Chakravarthy, B; Durkin, JP; Mealing, G; Morley, P; Song, D; Tremblay, R | 1 |
| Dee, MG; Donias, HW; Duva, MA; Stanley, BG; Willett, VL | 1 |
| Hu, XT; White, FJ | 1 |
| Barrios, M; Liljequist, S | 1 |
| Mennerick, S; Zorumski, CF | 1 |
| Giffard, RG; Panter, SS; Regan, RF; Tilly, JL; Witz, A | 1 |
| Mennerick, S; Que, J; Zorumski, CF | 1 |
| Feltz, P; Jo, YH; Poisbeau, P; Schlichter, R | 1 |
| Chang, YC; Gao, LH; Li, BF; Liu, CI; Wu, CL; Wu, TY | 1 |
| Koenig, ML; Meyerhoff, JL; Yourick, DL | 1 |
| Fleischer-Lambropoulos, E; Geladopoulos, T; Kazazoglou, T; Kentroti, S; Stefanis, C; Vernadakis, A | 1 |
| Abiko, Y; Hara, A; Kisara, K; Sakurada, C; Sakurada, S; Sakurada, T; Sugiyama, A; Tanno, K | 1 |
| Fiskum, G; Perry, DC; Rosenthal, RE; Wei, H | 1 |
| Albrecht, J; Borkowska, HD; Oja, SS; Saransaari, P | 1 |
| Chang, YC; Liu, CI; Wu, TY | 1 |
| Bulloch, AG; Lukowiak, K; Magoski, NS; McKenney, KK; Nesic, OB; Syed, NI | 1 |
| Chisamore, B; Dow, K; Solc, M | 1 |
| Bacskai, B; Pleasure, D; Yoshioka, A | 1 |
| Böhmer, G; Schmahl, C | 1 |
| Grino, M; Joanny, P; Oliver, C; Steinberg, J | 2 |
| Devau, G; Rabejac, D; Raymond, J | 1 |
| Chang, YC; Gean, PW; Hon, YS; Sue, TY; Tyan, SH | 1 |
| Chakravarthy, B; Durkin, JP; Mealing, G; Morley, P; Small, D; Song, D; Tremblay, R | 1 |
| Akaike, A; Kaneko, S; Maeda, T; Satoh, M | 1 |
| Miura, M; Suzuki, T; Takayama, K | 1 |
| Dow, KE; Wang, W | 1 |
| Folbergrová, J; Haugvicová, R; Lisý, V; Stastný, F | 1 |
| Fergus, A; Lee, KS | 1 |
| Inoue, T; Ito, KI; Kato, H; Mikoshiba, K; Miyakawa, H | 1 |
| Gershon, MD; Kirchgessner, AL; Liu, MT; Rothstein, JD | 1 |
| Häusser, M; Roth, A | 1 |
| Janáky, R; Jenei, Z; Oja, SS; Saransaari, P; Varga, V | 1 |
| Frandsen, A; Griffiths, R; Malcolm, C; Meredith, C; Ritchie, L; Rumsby, P; Schousboe, A; Scott, M | 1 |
| Talman, WT | 1 |
| Bonfanti, A; Pittaluga, A; Raiteri, M | 1 |
| Mifflin, SW; Zhang, J | 1 |
| Croucher, MJ; Patel, DR | 1 |
| Hunter, AJ; Rogers, DC | 1 |
| Fontana, G; Gemignani, A; Marchese, S; Raiteri, M | 1 |
| Cottrell, JE; Kass, IS; Zhu, H | 1 |
| Kohara, A; Ohno, K; Okada, M; Tsutsumi, R; Yamaguchi, T | 1 |
| Armstrong, DM; Ikonomovic, MD; Mishizen, A; Mishizin, A; Mizukami, K; Sheffield, R | 1 |
| Hirata, A; Kamakura, K; Kwak, S; Nagata, N; Nakamura, R | 1 |
| Arvola, M; Johnson, M; Keinänen, K; Kuusinen, A | 1 |
| Benjamin, PR; Brierley, MJ; Yeoman, MS | 1 |
| Almazan, G; Liu, HN; Molina-Holgado, E | 1 |
| Conejero, C; Dillon-Carter, O; Freed, WJ; Poltorak, M; Tornatore, C | 1 |
| Bezzi, P; Carmignoto, G; Pasti, L; Pozzan, T; Rizzini, BL; Rossi, D; Vesce, S; Volterra, A | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Malva, JO | 1 |
| Baltrons, MA; García, A | 1 |
| Brautigan, RA; Eagles, DA | 1 |
| Desai, NS; Leslie, KR; Nelson, SB; Rutherford, LC; Turrigiano, GG | 1 |
| Althomsons, SP; Choi, DW; Goldberg, MP; Hyrc, KL; McDonald, JW | 1 |
| Morgan, M; Navamani, M; Williams, RJ | 1 |
| Kumar, VS; Rabinowitz, D; Schwartz, TH; Smetters, DK; Tsiola, A; Unni, V; Yuste, R | 1 |
| Asztely, F; Kokaia, M; Kullmann, DM; Min, MY | 1 |
| Emmerson, PJ; Kinney, GA; Miller, RJ | 1 |
| Allan, SM; Lawrence, CB; Rothwell, NJ | 2 |
| Dougherty, PM; Lenz, FA; Mittman, S | 1 |
| González, MP; Herrero, MT; Oset-Gasque, MJ; Vicente, S | 1 |
| Horiuchi, K; Itoh, A; Itoh, T; Pleasure, D | 1 |
| Schwarzer, C; Sperk, G | 1 |
| López, T; López-Colomé, AM; Ortega, A | 1 |
| Lu, T; Shen, Y; Yang, XL | 1 |
| Sattler, R; Spetzler, RF; Tymianski, M; Zabramski, JM | 1 |
| Trombley, PQ | 1 |
| Black, IB; Crozier, RA; Levine, ES; Plummer, MR | 1 |
| Murali, SG; Sun, D | 1 |
| Browne, SE; Everitt, BJ; McCulloch, J; Muir, JL; Page, KJ; Robbins, TW | 1 |
| Bowie, D; Lange, GD; Mayer, ML | 1 |
| Richardson, CM; Wakerley, JB | 1 |
| Arnold, T; Ehrenberger, K; Felix, D; Oestreicher, E | 1 |
| Banno, T; Kohno, K | 1 |
| Banke, TG; Nielsen, BS; Pickering, DS; Schousboe, A | 1 |
| Lima, L; Matus, P; Obregón, F | 1 |
| Best, JD; Hastings, MH; McNulty, S; Schurov, IL; Sloper, PJ | 1 |
| Fryer, HJ; Kalb, RG; Knox, RJ; Strittmatter, SM | 1 |
| Hay, M; Lindsley, KA | 1 |
| D'Hooge, R; De Deyn, PP; Raes, A; Van Bogaert, PP; Van de Vijver, G | 1 |
| Akaike, N; Harata, N; Katayama, J | 1 |
| Gao, F; Wu, SM | 1 |
| Hargreaves, KM; Jackson, DL | 1 |
| Sako, N; Yamamoto, T | 1 |
| McCarthy, KD; Shelton, MK | 1 |
| Blanco, R; de la Villa, P | 1 |
| Ferrand, N; Gueritaud, JP; Ivanov, A; Kapus, G; Launey, T; Tarnawa, I | 1 |
| Capogna, M; Dürr, R; Gähwiler, BH; McKinney, RA; Thompson, SM | 1 |
| Alvarez, RM; Cárdenas, AM; Caviedes, P; Caviedes, R; Cortés, MP; Rapoport, SI; Rodríguez, MP; Shimahara, T; Wei, W | 1 |
| Marc, RE | 1 |
| Chen, X; Kombian, SB; Pittman, QJ; Zidichouski, JA | 1 |
| Bechtel, WD; Brambilla, A; Brenner, M; Ceci, A; Ensinger, HA; Palluk, R; Sagrada, A; Weiser, T; Wienrich, M | 1 |
| Perkinton, MS; Sihra, TS | 1 |
| Kretschmer, BD | 1 |
| Monogham, DT; Rosenquist, TH; Schneider, AM | 1 |
| Henry, JL; Pitcher, GM | 1 |
| Cornish, JL; Duffy, P; Kalivas, PW | 1 |
| Arnold, T; Ehrenberger, K; Felix, D; Kleinlogel, S; Oestreicher, E | 1 |
| Sensi, SL; Weiss, JH; Yin, HZ | 1 |
| Abele, R; Keinänen, K; Kuusinen, A; Madden, DR | 1 |
| Chesler, M; Smith, SE | 1 |
| Standley, CA | 1 |
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| Clausen, RP; Furukawa, H; Hansen, KB; Jørgensen, L; Ogden, KK; Perszyk, RE; Risgaard, R; Tajima, N; Traynelis, SF; Vance, KM | 1 |
| Thanapitak, S; Toumazou, C | 1 |
| Brockie, PJ; Dunn, PJ; Hoerndli, F; Jensen, E; Jensen, M; Madsen, DM; Maricq, AV; Maxfield, D; Mellem, JE; Thacker, C; Tomita, S; Wang, R; Yamasaki, T | 1 |
| Gipson, CD; Huits, M; Kalivas, PW; Shen, HW | 1 |
| Brown, AM; Chen, S; Evans, RD; Hamner, MA; Ransom, BR; Yang, X; Ye, ZC | 1 |
| Chen, PC; Heinzelmann, G; Kuyucak, S | 1 |
| Li, H; Li, W; Wang, P | 1 |
| Bhargava, A; Gong, K; Jasmin, L; Kung, LH; Magni, G | 1 |
| Dziewczapolski, G; Galimi, F; Ghetti, A; Heinemann, SF; Huitron-Resendiz, S; Lee, HS; Piña-Crespo, JC; Pinto-Duarte, A; Roberts, AJ; Sejnowski, TJ; Verma, IM; Wang, X | 1 |
| Blackshaw, S; Fu, C; Hu, S; Ma, TM; Paul, BD; Snyder, SH; Wolosker, H; Zhu, H | 1 |
| Kohlmeier, KA; McNair, LF | 1 |
| Deng, QQ; Liu, LL; Sheng, WL; Wang, MY; Weng, SJ; Yang, XL; Zhang, G; Zheng, C; Zhong, YM | 1 |
| Rodríguez-Manzo, G | 1 |
| Beckley, JT; Hughes, BA; Kalivas, PW; Randall, PK; Smith, RJ; Woodward, JJ | 1 |
| Fu, T; Guo, L; Huang, P; Li, C; Lu, Q; Xu, X | 1 |
| Farisello, L; Jones, SL; Mayer-Heft, N; Pfaus, JG | 1 |
| Chang, YC; Chen, EC; Chung, HW; Fang, W; Hsu, WL; Lee, YT; Wu, CY; Wu, HI | 1 |
| Akaike, N; Kotani, N; Wakita, M; Yamaga, T | 1 |
| Baranovic, J; Plested, AJ | 1 |
| Cabrera-Pastor, A; Felipo, V; Llansola, M; Taoro, L | 1 |
| Buttigieg, D; Steinschneider, R; Verleye, M | 1 |
| Kim, MH; von Gersdorff, H | 1 |
| Bermúdez-Rattoni, F; Guzmán-Ramos, K; Osorio-Gómez, D | 1 |
| Chianca, DA; de Menezes, RC; Machado, NL; Silva, FC | 1 |
| Di Maio, V; Santillo, S; Ventriglia, F | 1 |
| Gu, X; Lu, W; Mao, X | 1 |
| Artigas, F; Castañé, A; Gasull-Camós, J; Tarrés-Gatius, M | 1 |
| Pelosi, A | 1 |
| Escobar, ML; Gonsebatt, ME; Hernández-Mercado, K; Massieu, L; Montiel, T; Nelson-Mora, J; Rodríguez, VM; Rodríguez-Durán, L | 1 |
| Avendaño, C; Fernández-Montoya, J; Negredo, P | 1 |
| Gilbert, JR; Nugent, AC; Wills, KE; Yarrington, JS; Zarate, CA | 1 |
| Ariffin, MZ; Ibrahim, KM; Khanna, S; Lee, AT; Lee, RZ; Liu, EHC; Low, CM; Poon, SY; Thong, HK | 1 |
| Bellone, C; Bimpisidis, Z; Creed, M; Dorst, MC; Dumas, S; Lüscher, C; Papathanou, M; Pettersson, H; Silberberg, G; Wallén-Mackenzie, Å | 1 |
| Bobadilla, AC; Gipson, CD; Heinsbroek, JA; Kalivas, PW; Roberts-Wolfe, DJ; Smith, ACW; Spencer, SM | 1 |
| Chen, SJ; Chen, WS; Chien, CS; Chiou, GY; Chiou, SH; Hsu, CC; Hwang, DK; Lin, TC; Lin, TW; Nguyen, PNN; Peng, CH; Tsai, CY; Yang, YP; Yarmishyn, AA | 1 |
| Goswami, K; Nandakumar, DN; Prasad, C; Ramaswamy, P; Srinivas, D | 1 |
| Callison, JJ; Cook-Snyder, DR; McCarthy, N; Miller, JR; Navarrete-Opazo, AA; Palkovic, B; Stucke, AG; Stuth, EAE; Zuperku, EJ | 1 |
| Blain, EJ; Bonnet, CS; Gilbert, SJ; Mason, DJ; Williams, AS | 1 |
| Fakler, B; Schwenk, J | 1 |
| Affinnih, N; Brazhe, A; D'Brant, LY; De Guzman, RM; Khmaladze, A; Leapman, RD; McCauley, JP; Migliore, M; Migliore, R; Petroccione, MA; Scimemi, A; Semyanov, A; Shree, S; Sousa, AA; Todd, GC; Wisnoski, JJ; Zahid, S; Zuloaga, DG | 1 |
| Brüll, M; Falt, T; Karreman, C; Klima, S; Leist, M; Schwamborn, JC; Spreng, AS; Suciu, I; Waldmann, T | 1 |
| Chuang, AY; Chuang, HH; Huang, CS; Lai, YC; Wang, GH; Yang, YC; Yeh, JY | 1 |
| Abou-Elnaga, AF; Calva, CB; Cover, CG; Don, RF; Ikemoto, S; Junn, S; Kesner, AJ; Lu, H; Potter, CT; Ramsey, LA; Shin, R; Wang, DV; Yang, Y | 1 |
| Gugustea, R; Jia, Z | 1 |
| Karlov, DS; Lavrov, MI; Palyulin, VA; Radchenko, EV; Tarakanova, AS | 1 |
| Bhardwaj, A; Bhardwaj, R; Dhawan, DK; Kaur, T; Sharma, S; Sharma, SK | 1 |
| Malkin, SL; Postnikova, TY; Smolensky, IV; Zaitsev, AV; Zakharova, MV; Zubareva, OE | 1 |
| Campello-Costa, P; Goulart, VG; Landeira-Fernandez, J; Maisonnette, S; Pandolfo, P; Rocha-Mendonça, H | 1 |
| Ding, D; Jiang, H; Qi, W; Salvi, R | 1 |
| Kamanaka, G; Kanemaru, M; Oka, JI; Sanai, E; Sasaki-Hamada, S | 1 |
| Anders, S; Becker, AJ; Dietrich, D; Doengi, M; Halka, L; Henneberger, C; Kavalali, ET; Lamprecht, A; Matthews, EA; McMahon, SM; Müller, JA; Pfeifer, A; Pitsch, J; Schoch, S; Stein, V; Steinlein, P; Sun, W; van Dyk, G; Vana, NS | 1 |
| Bowie, D | 1 |
| Baranovic, J; Braunbeck, S; Chebli, M; Minniberger, S; Plested, AJR; Zaki, N | 1 |
| Kiyonaka, S; Ojima, K; Sugihara, Y | 1 |
| Bdir, S; Hawash, M; Jaradat, N; Qneibi, M | 1 |
| Anstötz, M; Ferraguti, F; Kasugai, Y; Lübke, JHR; Molnar, E; Rollenhagen, A; Sätzler, K; Zimmermann, K | 1 |
| Cha, S; Guo, G; Li, J; Meng, L; Wu, F; Zhang, H; Zhang, J; Zhang, W; Zhu, W | 1 |
| Khatib, T; McCaffery, P; Müller, B | 1 |
| Bdir, S; Hawash, M; Nacak Baytas, S; Qneibi, M | 1 |
| Chang, A; Chang, Y; Wang, SJ | 1 |
| Dash, SS; Kandy, SK; Markandeya, YS; Mehta, B; Nimonkar, MM | 1 |
| Bdir, S; Hidmi, A; Nassar, S; Qneibi, M | 1 |
| Cheng, MC; Hsu, SH; Hu, TM; Lin, KH; Tsai, HY | 1 |
| Golubeva, EA; Lavrov, MI; Palyulin, VA; Radchenko, EV | 1 |
| Huang, M; Liao, Y; Peng, Y; Shi, L; Shu, B; Wang, X; Xie, J; Xu, J | 1 |
| Bowie, D; Brown, PMGE; Perozzo, AM | 1 |
| Abdelhakam, DA; Aboul-Ela, YM; Aboul-Fotouh, S; Ebeid, MA; Elnahas, EM; Habib, MZ; Negm, EA; Sadek, DR; Tarek, M | 1 |
| Li, CH; Liu, YZ | 1 |
| Baradaran, R; Cais, O; Greger, IH; Ho, H; Ivica, J; Krieger, JM; Stockwell, I; Yamashita, K; Zhang, D | 1 |
| Gipson, CD; Hong, M; Khatri, SN; Maher, EE; Sadek, S; Stoops, WW; Ulangkaya, H; Woodcox, AM | 1 |
| Catalfio, AM; Ferrario, CR; Fetterly, TL | 1 |
23 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and glutamic acid
| Article | Year |
|---|---|
Glutamatergic neurotransmission in hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Dizocilpine Maleate; Dogs; Glutamic Acid; Hepatic Encephalopathy; Humans; In Vitro Techniques; Rats; Receptors, Glutamate; Synaptic Transmission | 1993 |
Glutamatergic transmission in the nucleus tractus solitarii: from server to peripherals in the cardiovascular information superhighway.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Baroreflex; Cardiovascular Physiological Phenomena; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Solitary Nucleus | 1997 |
Ligand recognition in glutamate receptors: insights from mutagenesis of the soluble alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-binding domain of glutamate receptor type D (GluR-D).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Binding Sites; Glutamic Acid; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Glutamate; Recombinant Proteins | 1997 |
The role of amino acid neurotransmitters in the regulation of pituitary gonadotropin release in fish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Female; Fishes; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropins, Pituitary; Luteinizing Hormone; Male; Models, Biological; N-Methylaspartate; Neurotransmitter Agents; Phylogeny; Sex Factors | 2000 |
[Glutamate receptors in the central nervous system].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Central Nervous System; Glutamic Acid; Hippocampus; Humans; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Role of excitatory amino acids in developmental epilepsies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Epilepsy; Excitatory Amino Acids; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Synaptic Transmission | 2001 |
Glutamate antagonists limit tumor growth.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antineoplastic Agents; Cell Division; Cell Movement; Drug Synergism; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; N-Methylaspartate; Tumor Cells, Cultured | 2002 |
Excitatory amino acids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acids; Glutamic Acid; Humans; N-Methylaspartate; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 2002 |
Presynaptic AMPA receptors: more than just ion channels?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; Humans; Ion Channels; Ligands; Models, Biological; Presynaptic Terminals; Receptors, AMPA; Receptors, Glutamate; Signal Transduction; Synaptic Transmission | 2004 |
Structural plasticity and tianeptine: cellular and molecular targets.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents, Tricyclic; Apoptosis; Atrophy; Dentate Gyrus; Depressive Disorder, Major; Glutamic Acid; Hippocampus; Humans; N-Methylaspartate; Neuronal Plasticity; Neurons; Serotonin; Thiazepines | 2002 |
Synaptic trafficking of glutamate receptors by MAGUK scaffolding proteins.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Models, Biological; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2007 |
Gating and permeation of kainate receptors: differences unveiled.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Ion Channel Gating; Neurons; Receptors, AMPA; Receptors, Ionotropic Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spermine; Synapses; Synaptic Transmission | 2010 |
Dimethyl sulfoxide as an excitatory modulator and its possible role in cancer pain management.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dimethyl Sulfoxide; Glutamic Acid; Humans; N-Methylaspartate; Neoplasms; Pain, Intractable; Quality of Life; Sodium Channels | 2010 |
The biochemistry, ultrastructure, and subunit assembly mechanism of AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Line; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Models, Molecular; Protein Conformation; Protein Subunits; Quinoxalines; Receptors, AMPA | 2010 |
A role for tumor necrosis factor-α in ischemia and ischemic preconditioning.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Ischemia; Glutamic Acid; Humans; Ischemic Preconditioning; N-Methylaspartate; Neurons; Receptors, Tumor Necrosis Factor; Signal Transduction; Tumor Necrosis Factor-alpha | 2011 |
AMPA receptor assembly: atomic determinants and built-in modulators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Binding Sites; Glutamic Acid; Humans; Models, Molecular; Neurons; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Protein Subunits; Receptors, AMPA; Synapses; Synaptic Transmission | 2012 |
How to build the fastest receptor on earth.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; Humans; Kinetics; Models, Molecular; Mutation; Protein Conformation; Receptors, AMPA | 2016 |
Cell-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonism reveals new insights in the development of parkinson's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Humans; Parkinson Disease | 2017 |
The Glutamatergic System in Primary Somatosensory Neurons and Its Involvement in Sensory Input-Dependent Plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ganglia, Sensory; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Neuralgia; Neuronal Plasticity; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Sensory Receptor Cells; Synaptic Transmission | 2017 |
Building of AMPA-type glutamate receptors in the endoplasmic reticulum and its implication for excitatory neurotransmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Endoplasmic Reticulum; Glutamic Acid; Receptors, AMPA; Synaptic Transmission | 2021 |
Genetic manipulations of AMPA glutamate receptors in hippocampal synaptic plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Genetically Modified; Gene Targeting; Glutamic Acid; Hippocampus; Learning; Mice; Models, Genetic; Neuronal Plasticity; Receptors, AMPA; Receptors, Glutamate | 2021 |
[Ligands of the AMPA-subtype glutamate receptors: mechanisms of action and novel chemotypes].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Ligands; Receptors, AMPA; Receptors, Glutamate | 2021 |
Diversity of AMPA Receptor Ligands: Chemotypes, Binding Modes, Mechanisms of Action, and Therapeutic Effects.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Brain; Glutamic Acid; Receptors, AMPA; Receptors, Glutamate | 2022 |
2 trial(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and glutamic acid
| Article | Year |
|---|---|
Norepinephrine modulates excitatory amino acid-induced responses in developing human and adult rat cerebral cortex.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Child; Child, Preschool; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Infant; Iontophoresis; Isoproterenol; Male; Membrane Potentials; Norepinephrine; Rats | 1994 |
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling.
Topics: Adolescent; Adult; Affect; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infusions, Intravenous; Ketamine; Magnetoencephalography; Male; Middle Aged; Models, Neurological; N-Methylaspartate; Time Factors; Treatment Outcome; Young Adult | 2018 |
637 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and glutamic acid
| Article | Year |
|---|---|
Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Cats; Electrophoresis; Ibotenic Acid; In Vitro Techniques; Molecular Conformation; Neurons; Oxazoles; Quantum Theory; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord; Structure-Activity Relationship; Synaptic Membranes | 1985 |
Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Oxazoles; Rats; Stereoisomerism | 1983 |
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Magnetic Resonance Spectroscopy; Molecular Structure; N-Methylaspartate; Receptors, Metabotropic Glutamate | 1996 |
Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes.
Topics: Alanine; Cell Line; Excitatory Amino Acid Agonists; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrimidinones; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Triazines; Uracil | 1997 |
Structure--activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines.
Topics: Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Isomerism; Models, Chemical; N-Methylaspartate; Phencyclidine; Quinoxalines; Radioligand Assay; Rats; Receptors, AMPA; Structure-Activity Relationship; Tyrosine | 1997 |
Synthesis and enantiopharmacology of new AMPA-kainate receptor agonists.
Topics: Animals; Cerebral Cortex; Convulsants; Excitatory Amino Acid Agonists; In Vitro Techniques; Isoxazoles; Male; Mice; Mice, Inbred DBA; Models, Molecular; Molecular Conformation; Proline; Pyrroles; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Stereoisomerism | 1999 |
Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding Sites; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Tertiary; Quinoxalines; Receptors, AMPA; Structure-Activity Relationship; Zinc | 2000 |
Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors.
Topics: Alanine; Animals; Animals, Newborn; Calcium; Cell Line; Humans; In Vitro Techniques; Long-Term Potentiation; Mossy Fibers, Hippocampal; Nerve Fibers, Unmyelinated; Protein Subunits; Pyrimidinones; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Spinal Cord; Spinal Nerve Roots; Stereoisomerism; Structure-Activity Relationship; Uracil | 2005 |
Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.
Topics: Crystallography, X-Ray; Glutamate Carboxypeptidase II; Humans; Models, Molecular; Molecular Mimicry; Protein Conformation; Recombinant Proteins | 2007 |
The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.
Topics: Animals; Cell Line; Crystallography, X-Ray; Drug Design; Excitatory Amino Acid Agonists; Humans; Models, Molecular; Propionates; Receptors, Kainic Acid; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis | 2009 |
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Agonists; HEK293 Cells; Humans; Ligands; Rats; Receptors, AMPA; Synaptosomes; Triazoles | 2019 |
Heterocyclic excitatory amino acids. Synthesis and biological activity of novel analogues of AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Electrophysiology; Heterocyclic Compounds; Ibotenic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Structure-Activity Relationship | 1992 |
Syntheses and conformational analyses of glutamate analogs: 2-(2-carboxy-3-substituted-cyclopropyl)glycines as useful probes for excitatory amino acid receptors.
Topics: Animals; Central Nervous System; Glutamates; Glycine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Probes; Rats; Receptors, Glutamate | 1996 |
AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Glutamic Acid; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Thiazoles | 1997 |
Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.
Topics: Animals; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Cerebellum; CHO Cells; Cricetinae; Cyclic AMP; Cycloleucine; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Inositol Phosphates; Kidney; Ligands; Models, Molecular; Molecular Conformation; Norbornanes; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism | 1998 |
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.
Topics: Animals; Cell Line; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Humans; Ligands; Molecular Structure; Oocytes; Pyrimidinones; Rats; Receptors, Glutamate; Spodoptera; Structure-Activity Relationship; Thiophenes; Xenopus laevis | 2008 |
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA | 2010 |
4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues.
Topics: Amino Acids, Acidic; Animals; Brain; Cell Line; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Vitro Techniques; Male; Oocytes; Oxadiazoles; Patch-Clamp Techniques; Potentiometry; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis | 2010 |
Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Neurotransmitter; Recombinant Proteins; Xenopus laevis | 1992 |
Agonist- and subunit-dependent potentiation of glutamate receptors by a nootropic drug aniracetam.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Psychotropic Drugs; Pyrrolidinones; Rats; Receptors, Glutamate; Xenopus laevis | 1992 |
Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane Permeability; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Transport; Kainic Acid; Pyramidal Tracts; Rats; Receptors, Glutamate | 1992 |
Evidence that [3H]glutamate binding sites are masked by biologically relevant endogenous factor on cell membranes of frog spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cytosol; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Piperazines; Quisqualic Acid; Rana catesbeiana; Spinal Cord | 1992 |
Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Models, Neurological; Nerve Fibers; Neurons; Pyramidal Tracts; Rats; Synapses | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Transmitter-operated channels in rabbit retinal astrocytes studied in situ by whole-cell patch clamping.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Bicuculline; Chloride Channels; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Membrane Proteins; Quisqualic Acid; Rabbits; Receptors, GABA-A; Retina; Time Factors | 1992 |
Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Pertussis Toxin; Quisqualic Acid; Time Factors; Virulence Factors, Bordetella | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
Fast excitatory postsynaptic potentials and the responses to excitant amino acids of sympathetic preganglionic neurons in the slice of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1992 |
Excitatory amino acid receptors on isolated retinal ganglion cells from the goldfish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retinal Ganglion Cells; Sodium | 1992 |
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neu
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dantrolene; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Verapamil | 1992 |
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Magnesium; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains | 1992 |
Glutamic acid-insensitive [3H]kainic acid binding in goldfish brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; Ligands; Neurotoxins; Tissue Distribution; Tritium | 1992 |
Purification of AMPA type glutamate receptor by a spider toxin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cattle; Cerebellum; Chloride Channels; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Liposomes; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Spider Venoms | 1992 |
NMDA treatment and K(+)-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellar Cortex; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1992 |
L-glutamate-evoked release of dopamine from synaptosomes of the rat striatum: involvement of AMPA and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical; Synaptosomes | 1992 |
Gamma-D-glutamylaminomethyl sulfonic acid (GAMS) distinguishes subtypes of glutamate receptor in the chick cochlear nucleus (nuc. magnocellularis).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Chickens; Cochlea; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Kainic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Drug Synergism; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Myocardial Contraction; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Acetylcholine release from the rabbit retina mediated by kainate receptors.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Choline; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rabbits; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina | 1991 |
Neurochemical characterization of excitotoxin lesions in the cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Exocytosis; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Taurine | 1991 |
Kinetic analysis of interactions between kainate and AMPA: evidence for activation of a single receptor in mouse hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Mice; Neurons; Quisqualic Acid; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1991 |
Alterations in cortical [3H]kainate and alpha-[3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chronic Disease; Dizocilpine Maleate; Dogs; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Ibotenic Acid; Kainic Acid; Ligands; Tritium | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Purkinje Cells; Receptors, Amino Acid; Receptors, Cell Surface; Time Factors | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Quisqualate agonists occlude kainate-induced current in cultured striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Drug Interactions; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neurons; Quisqualic Acid | 1991 |
Solubilization, characterization, and partial purification of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-, quisqualate-, kainate-sensitive L-glutamate binding sites from porcine brain synaptic junctions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chromatography; Detergents; Glutamates; Glutamic Acid; Hot Temperature; Ibotenic Acid; Kainic Acid; Octoxynol; Polyethylene Glycols; Quisqualic Acid; Solubility; Synapses | 1991 |
Presynaptic facilitation of dopamine release through D,L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors on synaptosomes from the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dipeptides; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Nerve Endings; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptosomes; Tritium | 1991 |
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid electrophysiological and neurotoxic effects in the guinea-pig cochlea.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlear Microphonic Potentials; Dendrites; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Ibotenic Acid; Male; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Vestibulocochlear Nerve | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Intercellular action of nitric oxide in adult rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine | 1991 |
Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Neurons; Phorbol Esters; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Vinpocetine preferentially antagonizes quisqualate/AMPA receptor responses: evidence from release and ligand binding studies.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membranes; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium; Vinca Alkaloids | 1991 |
Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1990 |
Glutamate: three meetings but how many receptors? Excitatory Amino Acids 1990: a Fidia Research Foundation Symposium, Padua, Italy, May 21-26, 1990. Excitatory Amino Acid Receptors in the Brain: Functions and Disorders, Montreal, Canada, June 23-24, 1990.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; GTP-Binding Proteins; Ibotenic Acid; Ion Channel Gating; Ion Channels; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction | 1990 |
Reduction of desensitization of a glutamate ionotropic receptor by antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channels; Membrane Potentials; Oocytes; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1991 |
Functional expression of the alpha 1 subunit of the AMPA-selective glutamate receptor channel, using a baculovirus system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baculoviridae; DNA, Recombinant; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; Ibotenic Acid; Insecta; Ion Channels; Kainic Acid; Kinetics; Mice; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Transfection | 1991 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Oxadiazoles; Oxazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
The ontogeny of excitatory amino acid receptors in rat forebrain--I. N-methyl-D-aspartate and quisqualate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ammonia; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; Down-Regulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Liver; Male; N-Methylaspartate; Organ Size; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamus | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
The expression of excitatory amino acid binding sites during neuritogenesis in the developing rat cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebellum; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Oxazoles; Rats; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium Chloride; Carbachol; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Oxadiazoles; Oxazoles; Potassium Chloride; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Cerebellar Cortex; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Olivopontocerebellar Atrophies; Oxadiazoles; Receptors, AMPA; Receptors, Neurotransmitter; Reference Values; Spinocerebellar Degenerations; Tritium | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Cats; Electrodes; Glutamates; Glutamic Acid; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Retinal Ganglion Cells | 1990 |
Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Autoradiography; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Neurotransmitter | 1990 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
A voltage-clamp study of isolated stingray horizontal cell non-NMDA excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Separation; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fishes; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Hypoglycemia; Ibotenic Acid; Insulin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using L-[3H]glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Software; Tritium | 1989 |
Early warning for LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Synapses; Time Factors | 1989 |
Displacement of excitatory amino acid receptor ligands by acidic oligopeptides.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1985 |
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1986 |
Binding sites for [3H]glutamate and [3H]aspartate in human cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aspartic Acid; Binding Sites; Calcium Chloride; Cerebellum; Dicarboxylic Acids; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Oxadiazoles; Quisqualic Acid | 1986 |
Characterization of quisqualate-type L-glutamate receptors in the retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Binding, Competitive; Chickens; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ibotenic Acid; Kinetics; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Subcellular Fractions | 1987 |
Characterization of quisqualate recognition sites in rat brain tissue using DL-[3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) and a filtration assay.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chemical Phenomena; Chemistry; Filtration; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Thiocyanates | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
Characterization and regional distribution of glutamatergic and cholinergic ligand binding sites in goldfish brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Cyprinidae; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; Ligands; Ocular Physiological Phenomena; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1988 |
alpha-[3H]Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding to rat striatal membranes: effects of selective brain lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Denervation; Dopamine; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Ibotenic Acid; Membranes; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
Maturational changes in retinal excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Chick Embryo; Embryonic and Fetal Development; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1988 |
The binding of [3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Female; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ibotenic Acid; Male; Mathematics; Oxazoles; Rats; Rats, Inbred Strains | 1982 |
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Ibotenic Acid; Interneurons; Oxazoles; Spinal Cord; Stereoisomerism; Synaptic Transmission; Valine | 1982 |
The ionic mechanisms associated with the excitatory response of kainate, L-glutamate, quisqualate, ibotenate, AMPA and methyltetrahydrofolate on leech Retzius cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Ganglia; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Leeches; Membrane Potentials; Neurons; Osmolar Concentration; Oxadiazoles; Oxazoles; Pyrrolidines; Quisqualic Acid; Sodium; Tetrahydrofolates | 1984 |
Effects of a spider toxin and its analogue on glutamate-activated currents in the hippocampal CA1 neuron after ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Calcium; Electrophysiology; Excitatory Amino Acid Agonists; Gerbillinae; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Neurotoxins; Patch-Clamp Techniques; Spider Venoms; Synapses | 1995 |
L-glutamate-induced changes in intracellular calcium oscillation frequency through non-classical glutamate receptor binding in cultured rat myocardial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Intracellular Fluid; Kainic Acid; Myocardium; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Rats; Receptors, Amino Acid; Riluzole; Thiazoles | 1995 |
Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamic Acid; Kainic Acid; Nerve Degeneration; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1995 |
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Male; Microdialysis; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Serine | 1993 |
Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cells, Cultured; Dicarboxylic Acids; Drug Synergism; Embryo, Mammalian; Female; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Macrophages; Neuroglia; Neurons; Neurotoxins; Pregnancy; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1993 |
Glutamate agonist-induced hippocampal lesion and nitric oxide synthase/NADPH-diaphorase: a light and electron microscopical study in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Benzothiazoles; Brain Diseases; Glutamates; Glutamic Acid; Hippocampus; Microscopy, Electron; NADPH Dehydrogenase; Neurons; Nitric Oxide; Nitric Oxide Synthase; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts | 1993 |
Training chicks on a passive avoidance task modulates glutamate-stimulated inositol phosphate accumulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Avoidance Learning; Chickens; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Inositol Phosphates; Male; Neurotoxins; Prosencephalon; Receptors, Glutamate | 1993 |
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Female; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Lanthanum; N-Methylaspartate; Neurons; Neurotoxins; Photometry; Potassium; Pregnancy; Presynaptic Terminals; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Membrane currents evoked by excitatory amino acid agonists in ON bipolar cells of the mudpuppy retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Animals; Cadmium; Cell Membrane; Cobalt; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Necturus maculosus; Neurotransmitter Agents; Receptors, Amino Acid; Retina | 1993 |
Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Glutamates; Glutamic Acid; Hippocampus; Homeostasis; Kinetics; Lymphotoxin-alpha; N-Methylaspartate; Neurons; Neurotoxins; Rats; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Glutamate-evoked release of arachidonic acid from mouse brain astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurotoxins; Organ Specificity; Quisqualic Acid; Receptors, Glutamate; Time Factors; Tritium | 1994 |
Glutamate- and AMPA-mediated calcium influx through glutamate receptor channels in medial septal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Calcium; Calcium Channels; Dendrites; Glutamates; Glutamic Acid; In Vitro Techniques; Iontophoresis; Kainic Acid; Membrane Potentials; Neurons; Prosencephalon; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence | 1993 |
The lateral hypothalamus: a primary site mediating excitatory amino acid-elicited eating.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Feeding Behavior; Glutamates; Glutamic Acid; Hypothalamic Area, Lateral; Injections; Kainic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley | 1993 |
Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Glycine; Hippocampus; Intracellular Signaling Peptides and Proteins; Ionomycin; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1994 |
Potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-selective glutamate receptor function by a nootropic drug, idebenone.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoquinones; Concanavalin A; Dose-Response Relationship, Drug; Electrophysiology; Female; Glutamates; Glutamic Acid; Oocytes; Receptors, Glutamate; RNA, Complementary; Ubiquinone; Xenopus laevis | 1994 |
Dexamethasone potentiates NMDA receptor-mediated neuronal injury in the postnatal rat.
Topics: Aldosterone; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Autoradiography; Blood Glucose; Brain; Dexamethasone; Electron Transport Complex IV; Glutamates; Glutamic Acid; Kainic Acid; Metyrapone; N-Methylaspartate; Neurotransmitter Agents; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain Ischemia; Cochlea; Cochlear Microphonic Potentials; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Male; N-Methylaspartate; Neurons, Afferent; Neurotransmitter Agents; Perfusion; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1994 |
Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electrophysiology; Glutamates; Glutamic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1994 |
Role of Ca2+ in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-mediated polyphosphoinositide turnover in primary neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcimycin; Calcium; Carbachol; Cells, Cultured; Cobalt; Extracellular Space; Glutamates; Glutamic Acid; Neurons; Phosphatidylinositol Phosphates; Rats; Tetrodotoxin; Time Factors | 1994 |
Species-dependent functional properties of non-NMDA receptors expressed in Xenopus laevis oocytes injected with mammalian and avian brain mRNA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain Chemistry; Cattle; Chickens; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Membrane Potentials; Oocytes; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Species Specificity; Xenopus laevis | 1994 |
High-level expression of functional glutamate receptor channels in insect cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baculoviridae; Cell Line; Detergents; Electrophysiology; Gene Expression; Gene Transfer Techniques; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Kinetics; Moths; Receptors, Glutamate | 1994 |
Selective RNA editing and subunit assembly of native glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Base Sequence; Cell Line; Cerebral Cortex; Codon; Electric Conductivity; Glutamates; Glutamic Acid; Humans; Immunosorbent Techniques; Ion Channels; Kainic Acid; Molecular Sequence Data; Oligodendroglia; Polymerase Chain Reaction; Rats; Receptors, Glutamate; RNA; RNA Editing; RNA Splicing; Stem Cells | 1994 |
Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Nerve Degeneration; Neurons; Nicotine; Parasympathetic Nervous System; Parasympathomimetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin | 1994 |
Dopamine alters glutamate receptor desensitization in retinal horizontal cells of the perch (Perca fluviatilis).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Dopamine; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Perches; Pyrrolidinones; Quisqualic Acid; Receptors, Glutamate; Retina; Time Factors | 1994 |
Glutamate receptor-driven activation of transcription factors in primary neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Base Sequence; Binding Sites; Cell Nucleus; Cell Survival; Cells, Cultured; Cycloleucine; Embryo, Mammalian; Gene Expression; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Mice; Molecular Sequence Data; N-Methylaspartate; Neurons; Proto-Oncogene Proteins; Proto-Oncogenes; Quisqualic Acid; Rats; Receptors, Glutamate; Transcription Factors | 1994 |
Possible role of glutamatergic neurotransmission in regulating ethanol-evoked brain ascorbate release.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ascorbic Acid; Brain Chemistry; Dicarboxylic Acids; Electrophysiology; Ethanol; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Injections, Intraventricular; Kainic Acid; Male; Microelectrodes; N-Methylaspartate; Neostriatum; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1994 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
Effects of L-glutamate on the responses to nerve stimulation in rat isolated atria.
Topics: Adrenergic Fibers; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Atrial Function; Electric Stimulation; Female; Glutamates; Glutamic Acid; Heart Atria; Heart Rate; In Vitro Techniques; Kainic Acid; Male; Muscarinic Antagonists; N-Methylaspartate; Norepinephrine; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar | 1994 |
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cytosol; Dizocilpine Maleate; Fetus; Glucose; Glutamic Acid; Glycine; Hypothermia, Induced; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurons | 1994 |
Release of the nitric oxide precursor, arginine, from the thalamus upon sensory afferent stimulation, and its effect on thalamic neurons in vivo.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Glutamic Acid; Male; N-Methylaspartate; Neurons; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium; Rats; Rats, Wistar; Synaptic Transmission; Thalamus; Vibrissae | 1994 |
Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Fetus; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Potassium Chloride; Quisqualic Acid | 1994 |
Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Phosphopyruvate Hydratase; Propofol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 1994 |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain Diseases; Cell Death; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Isoquinolines; Male; Malonates; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Thyrotropin-releasing hormone enhances excitatory postsynaptic potentials in neocortical neurons of the rat in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Stimulation; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Thyrotropin-Releasing Hormone | 1994 |
Cyclothiazide unmasks AMPA-evoked stimulation of [3H]-L-glutamate release from rat hippocampal synaptosomes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Carbachol; Diuretics; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Potassium; Presynaptic Terminals; Rats; Rats, Wistar; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical; Synaptosomes | 1994 |
Potentiation of synaptic transmission in the rat hippocampal slice by exogenous L-glutamate and selective L-glutamate receptor subtype agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Iontophoresis; N-Methylaspartate; Nerve Fibers; Neurotoxins; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Synapses; Synaptic Transmission | 1994 |
Aluminium reduces glutamate-activated currents of rat hippocampal neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aluminum; Animals; Electric Conductivity; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Osmolar Concentration; Rats; Rats, Wistar | 1994 |
Taurine release from mouse hippocampal slices: effects of glutamatergic substances and hypoxia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Nitrogen; Oxygen; Potassium; Quisqualic Acid; Taurine | 1994 |
Intracerebral microdialysis combined with recording of extracellular field potential: a novel method for investigation of depolarizing drugs in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Polarity; Electroencephalography; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Kainic Acid; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Neostriatum; Rats; Rats, Sprague-Dawley | 1994 |
Modulation of dopamine and noradrenaline release and of intracellular Ca2+ concentration by presynaptic glutamate receptors in hippocampus.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channel Blockers; Catecholamines; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Presynaptic; Synaptosomes | 1994 |
Regional variations in the pharmacology of AMPA receptors as revealed by receptor autoradiography.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Cerebellar Cortex; Glutamic Acid; Indoles; Male; Molecular Structure; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides | 1994 |
Calcium dependence of glutamate receptor-evoked alkaline shifts in hippocampus.
Topics: Alkalies; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Extracellular Space; Glutamic Acid; Hippocampus; In Vitro Techniques; N-Methylaspartate; Potassium; Rats; Receptors, Glutamate | 1994 |
Modulation of neuropeptide FF release from rat spinal cord slices by glutamate. Involvement of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Membranes; N-Methylaspartate; Neuropeptides; Neurotoxins; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Cyclothiazide modulates AMPA receptor-mediated increases in intracellular free Ca2+ and Mg2+ in cultured neurons from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Drug Synergism; Glutamic Acid; Kainic Acid; Magnesium; Neurons; Prosencephalon; Rats; Receptors, AMPA | 1995 |
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1995 |
Interleukin-1 beta attenuates excitatory amino acid-induced neurodegeneration in vitro: involvement of nerve growth factor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Antibodies, Monoclonal; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acids; Fetus; Glutamic Acid; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Kainic Acid; Kinetics; N-Methylaspartate; Nerve Degeneration; Nerve Growth Factors; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sialoglycoproteins | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Dopamine enhances glutamate-activated currents in spinal motoneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Base Sequence; Benzazepines; Chick Embryo; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; Glutamic Acid; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Molecular Sequence Data; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Polymerase Chain Reaction; Receptors, Dopamine D1; RNA, Messenger; Spinal Cord; Time Factors | 1995 |
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors mediate excitotoxicity in the oligodendroglial lineage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Base Sequence; Cell Line; Gene Expression; Glutamic Acid; Ion Channels; Kainic Acid; Molecular Sequence Data; Neurotoxins; Oligodendroglia; Oligonucleotide Probes; Polymerase Chain Reaction; Rats; Receptors, AMPA; Receptors, Glutamate; Transcription, Genetic | 1995 |
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcimycin; Cerebral Cortex; Child; Cycloleucine; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Male; Middle Aged; N-Methylaspartate; Phosphatidylinositols; Quisqualic Acid; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrodotoxin | 1995 |
AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calbindins; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Embryo, Mammalian; Evoked Potentials; Glutamic Acid; Kainic Acid; Kinetics; Membrane Potentials; Microscopy, Fluorescence; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; S100 Calcium Binding Protein G; Time Factors | 1995 |
Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Communication; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Fetus; Glutamic Acid; Kinetics; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins | 1995 |
Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/Kainate receptors in organotypic hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Cell Differentiation; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1995 |
Tetrahydro-9-aminoacridine presynaptically inhibits glutamatergic transmission in the rat amygdala.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Atropine; Electric Stimulation; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Synaptic Transmission; Tacrine | 1995 |
Long-term enhancement of dopamine release by high frequency tetanic stimulation via a N-methyl-D-aspartate-receptor-mediated pathway in rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Male; N-Methylaspartate; Neostriatum; Nerve Endings; Potassium Chloride; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Patch sensor detection of glutamate release evoked by a single electrical shock.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biosensing Techniques; Electric Stimulation; Excitatory Amino Acids; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Nerve Fibers; Patch-Clamp Techniques; Pyramidal Cells; Rats | 1995 |
Excitatory amino acid receptor ligands: asymmetric synthesis, absolute stereochemistry and pharmacology of (R)- and (S)-homoibotenic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Radioligand Assay; Rats; Receptors, Glutamate; Stereoisomerism; Structure-Activity Relationship | 1995 |
GFAP-positive hippocampal astrocytes in situ respond to glutamatergic neuroligands with increases in [Ca2+]i.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Rats | 1995 |
Effect of thiocyanate on AMPA receptor mediated responses in excised patches and hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Models, Biological; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Temperature; Thiocyanates; Time Factors | 1995 |
Ca(2+)-permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium Channels; Dendrites; Diuretics; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Chloride Symporter Inhibitors | 1995 |
Subcellular localization and molecular pharmacology of distinct populations of [3H]-AMPA binding sites in rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Cell Fractionation; Glutamic Acid; Hippocampus; In Vitro Techniques; Isotope Labeling; Kainic Acid; Microscopy, Electron; Microsomes; Neuronal Plasticity; Protein Processing, Post-Translational; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Synaptosomes; Tritium | 1995 |
Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Glutamic Acid; Iontophoresis; Male; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1995 |
Pressor responses to stimulation of non-NMDA receptors in the superficial laminae of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Blood Pressure; Cats; Decerebrate State; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Microinjections; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Spinal Cord | 1995 |
NMDA and non-NMDA receptors contribute to synaptic transmission between the medial geniculate body and the lateral nucleus of the amygdala.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Electric Stimulation; Glutamic Acid; Male; Memory; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Basic fibroblast growth factor selectively increases AMPA-receptor subunit GluR1 protein level and differentially modulates Ca2+ responses to AMPA and NMDA in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Fibroblast Growth Factor 2; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Localisation of glutamate receptor binding sites and mRNAs to the dorsal horn of the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Neural Pathways; Phencyclidine; Rats; Receptors, Glutamate; RNA, Messenger; Spinal Cord; Substantia Gelatinosa | 1993 |
Binding of [3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and [3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cell Membrane; Dizocilpine Maleate; Female; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Receptors, Glutamate; Spermidine; Thiocyanates; Tissue Distribution | 1993 |
Thiocyanate equally increases affinity for two DL-alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA) receptor states.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Thiocyanates | 1993 |
Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus of the tractus solitarius of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Medulla Oblongata; Muscimol; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses | 1993 |
(R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors mediate a calcium-dependent inhibition of the metabotropic glutamate receptor-stimulated formation of inositol 1,4,5-trisphosphate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol 1,4,5-Trisphosphate; N-Methylaspartate; Protein Kinases; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Glutamate dehydrogenase improves binding of [3H]CGP39653 to NMDA receptors in the autoradiographic assay.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Neurotransmitter receptors and voltage-dependent Ca2+ channels encoded by mRNA from the adult corpus callosum.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antisense Elements (Genetics); Aspartic Acid; Astrocytes; Biomarkers; Calcium Channels; Cattle; Corpus Callosum; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Male; Membrane Potentials; Middle Aged; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA Probes; RNA, Messenger; Xenopus | 1993 |
Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Glutamate stimulates [3H]phorbol 12,13-dibutyrate binding in cultured Bergmann glia cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cells, Cultured; Cerebellum; Chick Embryo; Cytosol; Enzyme Activation; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neuroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purkinje Cells | 1993 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
The role of amino acid neurotransmitters in the descending control of electroreception.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Bicuculline; Dendrites; Electric Stimulation; Electrophysiology; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Microinjections; Neurons; Neurotransmitter Agents; Pyramidal Tracts; Quinoxalines; Sensory Receptor Cells | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Lateral hypothalamic injections of glutamate, kainic acid, D,L-alpha-amino-3-hydroxy-5-methyl-isoxazole propionic acid or N-methyl-D-aspartic acid rapidly elicit intense transient eating in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Eating; Glutamates; Glutamic Acid; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
AMPA and NMDA binding sites in the hypothalamic lateral tuberal nucleus: implications for Huntington's disease.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glucagon; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Islets of Langerhans; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Excitatory amino acid-induced slow biphasic responses of free intracellular calcium in human neuroblastoma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cycloleucine; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Tumor Cells, Cultured | 1993 |
Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Evoked Potentials; Glucose; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pipecolic Acids; Pyramidal Tracts; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tritium | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Calcium signaling of glial cells along mammalian axons.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aniline Compounds; Animals; Animals, Newborn; Axons; Calcium; Electric Stimulation; Fluorescent Dyes; Glutamates; Glutamic Acid; Kinetics; Microscopy, Fluorescence; Models, Neurological; Neuroglia; Neurons; Optic Nerve; Signal Transduction; Tetrodotoxin; Xanthenes | 1993 |
Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Cycloleucine; Electromyography; Glutamates; Glutamic Acid; Kainic Acid; Male; Muscles; N-Methylaspartate; Parkinson Disease; Rats; Receptors, Glutamate | 1993 |
Glutamate, GABA, glycine and taurine modulate serotonin synthesis and release in rostral and caudal rhombencephalic raphe cells in primary cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Neurons; Quinoxalines; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Taurine; Tryptophan | 1993 |
Opioid-glutamate interactions in rat locus coeruleus neurons.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission | 1993 |
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin | 1996 |
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission | 1996 |
AMPA receptors shape Ca2+ responses in cortical oligodendrocyte progenitors and CG-4 cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Oligodendroglia; Quinoxalines; Receptors, AMPA; Time Factors | 1995 |
Stimulation of serotonin release in the rat brain cortex by activation of ionotropic glutamate receptors and its modulation via alpha 2-heteroreceptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Glutamate; Serotonin | 1995 |
An ex vivo rat retinal preparation for excitotoxicity studies.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Rats; Rats, Sprague-Dawley; Retina | 1995 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Cloning, expression and pharmacological characterization of a human glutamate receptor: hGluR4.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; DNA, Complementary; Electrophysiology; Gene Expression; Glutamic Acid; Humans; Kainic Acid; Ligands; Molecular Sequence Data; Rats; Receptors, Glutamate; Sequence Homology, Amino Acid; Species Specificity; Transfection | 1995 |
Hippocampal CA1 lacunosum-moleculare interneurons: comparison of effects of anoxia on excitatory and inhibitory postsynaptic currents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Glutamic Acid; Hippocampus; Hypoxia, Brain; Interneurons; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Synaptic Transmission | 1995 |
Effects of repeated cold stress on aversive responses produced by intrathecal excitatory amino acids in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cold Temperature; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Stress, Psychological | 1995 |
In vivo electrochemical studies of the dynamic effects of locally applied excitatory amino acids in the striatum of the anesthetized rat.
Topics: Adolescent; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Cricetinae; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Humans; Kainic Acid; Male; N-Methylaspartate; Oxidation-Reduction; Potassium; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1996 |
Effects of decahydroisoquinoline-3-carboxylic acid monohydrate, a novel AMPA receptor antagonist, on glutamate-induced CA2+ responses and neurotoxicity in rat cortical and cerebellar granule neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamic Acid; Isoquinolines; Kainic Acid; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles | 1995 |
Modulation of 45Ca2+ influx into cells stably expressing recombinant human NMDA receptors by ligands acting at distinct recognition sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Radioisotopes; Cycloleucine; Dithionitrobenzoic Acid; Dithiothreitol; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Humans; Kainic Acid; L Cells; Ligands; Mice; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Spermine; Sulfhydryl Reagents | 1996 |
Decreased gonadotropin-releasing hormone neurosecretory response to glutamate agonists in middle-aged female rats on proestrus afternoon: a possible role in reproductive aging?
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arcuate Nucleus of Hypothalamus; Base Sequence; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Kainic Acid; Luteinizing Hormone; Median Eminence; Molecular Sequence Data; N-Methylaspartate; Preoptic Area; Proestrus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1996 |
Excitatory amino acid-induced neuronal cell death in rat cerebellar granule cell cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellum; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
Photoperiod regulates the LH response to central glutamatergic stimulation in the male Syrian hamster.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Gonadotropin-Releasing Hormone; Immunohistochemistry; Injections, Intraventricular; Luteinizing Hormone; Male; Mesocricetus; N-Methylaspartate; Photoperiod; Proto-Oncogene Proteins c-fos; Radioimmunoassay; Reproduction | 1993 |
Responses mediated by excitatory and inhibitory amino acid receptors in solitary spiking cells from normal newt retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; N-Methylaspartate; Patch-Clamp Techniques; Receptors, Amino Acid; Retina; Salamandridae | 1995 |
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium | 1996 |
Glutamate release evoked by glutamate receptor agonists in cultured chick retina cells: modulation by arachidonic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Benzofurans; Calcium Chloride; Cells, Cultured; Chick Embryo; Ethers, Cyclic; Excitatory Amino Acid Agonists; Fluorescent Dyes; Glutamic Acid; Indoles; Kainic Acid; Kinetics; N-Methylaspartate; Receptors, Glutamate; Retina; Sodium; Spectrometry, Fluorescence | 1996 |
Differential cellular response after glutamate analog hippocampal damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biomarkers; Brain; Brain Injuries; Cerebral Cortex; Cerebral Ventricles; Corpus Callosum; Glial Fibrillary Acidic Protein; Gliosis; Glutamic Acid; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Microglia; Neurons; Rats; Rats, Wistar | 1996 |
An early loss in membrane protein kinase C activity precedes the excitatory amino acid-induced death of primary cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Membrane; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; N-Methylaspartate; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1996 |
Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Weight; Circadian Rhythm; Eating; Excitatory Amino Acid Antagonists; Food Deprivation; Glutamic Acid; Hypothalamic Area, Lateral; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1996 |
Glutamate receptor regulation of rat nucleus accumbens neurons in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; N-Methylaspartate; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1996 |
Developmental changes in glutamate receptor-activated translocation of protein kinase C in cerebellar granule neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Carcinogens; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tritium | 1996 |
Domoic acid induces the release of glutamate in the rat hippocampal CA3 subregion.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Synaptosomes | 1996 |
Postsynaptic modulation of NMDA synaptic currents in rat hippocampal microcultures by paired-pulse stimulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Agonists; GABA Agonists; Glutamic Acid; Hippocampus; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 1996 |
Ultrastructure of excitotoxic neuronal death in murine cortical culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aurintricarboxylic Acid; Bisbenzimidazole; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dizocilpine Maleate; DNA Damage; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Mice; Microscopy, Electron; Mitochondria; Neuroglia; Neurons; Neurotoxins; Propidium; Protein Synthesis Inhibitors; Vacuoles | 1995 |
Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Benzothiadiazines; Calcium; Cells, Cultured; Cycloleucine; Evoked Potentials; Glutamic Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Virulence Factors, Bordetella; Wheat Germ Agglutinins | 1996 |
Electrophysiological characterization of non-NMDA glutamate receptors on cultured intermediate lobe cells of the rat pituitary.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Pituitary Gland; Quisqualic Acid; Rats; Receptors, Glutamate | 1996 |
Purification and biochemical characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate-sensitive L-glutamate receptors of pig brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Centrifugation, Density Gradient; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Gel, Two-Dimensional; Glutamic Acid; Kainic Acid; Molecular Weight; Octoxynol; Polyethylene Glycols; Potassium Chloride; Rats; Receptors, AMPA; Receptors, Kainic Acid; Solubility; Swine; Synaptic Membranes | 1996 |
Thyrotropin-releasing hormone (TRH) attenuates glutamate-stimulated increases in calcium in primary neuronal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Electrophysiology; Glutamic Acid; Intracellular Membranes; Ion Channel Gating; N-Methylaspartate; Neurons; Rats; Thyrotropin-Releasing Hormone | 1996 |
Stimulation of glutamine synthetase activity by excitatory amino acids in astrocyte cultures derived from aged mouse cerebral hemispheres may be associated with non-N-methyl-D-aspartate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamate-Ammonia Ligase; Glutamic Acid; Mice; N-Methylaspartate; Neurotoxins; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 1996 |
Involvement of nitric oxide in spinally mediated capsaicin- and glutamate-induced behavioural responses in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, Tachykinin; Spinal Cord | 1996 |
Non-NMDA glutamate receptor binding in canine brain after global cerebral ischemia and reperfusion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cardiopulmonary Resuscitation; Corpus Striatum; Dogs; Female; Glutamic Acid; Heart Arrest; Hippocampus; Ischemic Attack, Transient; Kainic Acid; Kinetics; Neurons; Organ Specificity; Parietal Lobe; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Reperfusion; Temporal Lobe; Time Factors; Tritium | 1996 |
Kainate and AMPA receptors in the rat brain in thioacetamide-induced hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Corpus Striatum; Glutamic Acid; Hepatic Encephalopathy; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 1996 |
A study of the oligomeric state of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring glutamate receptors in the synaptic junctions of porcine brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Azides; Brain; Centrifugation, Density Gradient; Chromatography, Gel; Cross-Linking Reagents; Dimethyl Adipimidate; Dimethyl Suberimidate; Glutamic Acid; Macromolecular Substances; Models, Chemical; Molecular Weight; Radioligand Assay; Receptors, AMPA; Swine; Synapses | 1996 |
Glutamate as a putative neurotransmitter in the mollusc, Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Diphosphate; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Nervous System Physiological Phenomena; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Quisqualic Acid; Synapses; Thionucleotides | 1996 |
Excitatory amino acid regulation of astrocyte proteoglycans.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; CD57 Antigens; Cell Membrane; Cells, Cultured; Chondroitin Sulfates; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Heparitin Sulfate; Hippocampus; Immunohistochemistry; Kainic Acid; N-Methylaspartate; Protein Kinase C; Rats; Receptors, Metabotropic Glutamate; Subcellular Fractions; Sulfates; Sulfur Radioisotopes | 1996 |
Pathophysiology of oligodendroglial excitotoxicity.
Topics: Acetylcysteine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aurintricarboxylic Acid; Benzothiadiazines; Biological Transport; Calcium; Cell Line; Cell Membrane; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Nerve Tissue Proteins; Oligodendroglia; Rats; Receptors, AMPA; RNA, Messenger | 1996 |
Effects of excitatory amino acids and neuropeptide Y on the discharge activity of suprachiasmatic neurons in rat brain slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine Agents; Male; N-Methylaspartate; Neurons; Neuropeptide Y; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Strychnine; Suprachiasmatic Nucleus | 1997 |
Glutamate and N-methyl-D-aspartate stimulate rat hypothalamic corticotropin-releasing factor secretion in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corticotropin-Releasing Hormone; Culture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hypothalamus; Kainic Acid; Male; N-Methylaspartate; Potassium Chloride; Rats; Rats, Wistar | 1997 |
AMPA receptors in cultured vestibular ganglion neurons: detection and activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Cells, Cultured; Ganglia, Sensory; Glutamic Acid; Immunohistochemistry; Mice; Mice, Inbred CBA; Neurons; Receptors, AMPA; Vestibular Nerve | 1997 |
A novel NMDA receptor antagonist protects against N-methyl-D-aspartate- and glutamate-induced neurotoxicity in the goldfish retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Glutamic Acid; Goldfish; Hippocampus; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Diseases | 1997 |
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Direct evidence for increase in excitatory amino acids release during mossy fiber LTP in rat hippocampal slices as revealed by the patch sensor methods.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Long-Term Potentiation; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Tetanus Toxin | 1997 |
Distribution and projection of the medullary cardiovascular control neurons containing glutamate, glutamic acid decarboxylase, tyrosine hydroxylase and phenylethanolamine N-methyltransferase in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axonal Transport; Blood Pressure; Cardiovascular System; Electric Stimulation; Glutamate Decarboxylase; Glutamic Acid; Glycine; Heart Rate; Male; Medulla Oblongata; Microelectrodes; N-Methylaspartate; Neurons; Phenylethanolamine N-Methyltransferase; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 1997 |
Differential regulation of neuronal proteoglycans by activation of excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Cycloleucine; DNA Primers; Excitatory Amino Acid Agonists; Fetus; Glutamic Acid; Glycosylphosphatidylinositols; Glypicans; Heparan Sulfate Proteoglycans; Hippocampus; Lectins, C-Type; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurocan; Neurons; Neuroprotective Agents; Polymerase Chain Reaction; Proteoglycans; Rats; Receptors, Glutamate; RNA, Messenger; Transcription, Genetic | 1997 |
Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: effect of homocysteine-induced seizures.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Reference Values; Seizures; Synaptic Membranes; Tritium | 1997 |
Regulation of cerebral microvessels by glutamatergic mechanisms.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Cerebrovascular Circulation; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microcirculation; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses; Vasoconstriction; Vasodilation | 1997 |
Glutamate-induced hyperpolarization in mouse cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Purkinje Cells; Quisqualic Acid | 1993 |
Glutamatergic enteric neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Benzothiadiazines; Calcium; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hexamethonium; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Microscopy, Immunoelectron; Muscle, Smooth; Myenteric Plexus; Neurons; Nicotine; Organelles; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin | 1997 |
Dendritic and somatic glutamate receptor channels in rat cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Kinetics; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cysteine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; RNA, Messenger | 1997 |
Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cerebral Cortex; Choline; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Norepinephrine; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Serotonin; Synaptosomes | 1997 |
Influences of excitatory amino acid receptor agonists on nucleus of the solitary tract neurons receiving aortic depressor nerve inputs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aorta; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Nervous System Physiological Phenomena; Neurons; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 1997 |
Evidence for a role of presynaptic AMPA receptors in the control of neuronal glutamate release in the rat forebrain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Benzothiadiazines; Binding, Competitive; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neurons; Presynaptic Terminals; Prosencephalon; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1997 |
Dissociation of effects of glutamate receptor antagonists on excitotoxic and hypoxic neuronal cell death in a novel rat cortical culture system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cytological Techniques; Glutamic Acid; Hypoxia; N-Methylaspartate; Neurons; Neurotoxins; Rats; Receptors, Glutamate | 1997 |
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Effect of excitatory amino acids on rat hypothalamic somatostatin secretion in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Hypothalamus; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Potassium Chloride; Rats; Rats, Wistar; Receptors, Glutamate; Somatostatin | 1997 |
The effect of thiopental and propofol on NMDA- and AMPA-mediated glutamate excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Intravenous; Animals; Dimethyl Sulfoxide; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Propofol; Rats; Rats, Sprague-Dawley; Thiopental | 1997 |
Kainate excitotoxicity is mediated by AMPA- but not kainate-preferring receptors in embryonic rat hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 1997 |
Alterations of AMPA-selected glutamate subtype immunoreactivity in the dentate gyrus after perforant pathway lesion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Glutamic Acid; Immunohistochemistry; Male; Perforant Pathway; Rats; Rats, Sprague-Dawley | 1997 |
AMPA receptor-mediated slow neuronal death in the rat spinal cord induced by long-term blockade of glutamate transporters with THA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Cell Death; Glutamic Acid; Hindlimb; Infusions, Parenteral; Injections, Spinal; Male; Motor Activity; Neurons; Paralysis; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Subarachnoid Space; Tail; Time Factors; Urinary Incontinence | 1997 |
Glutamate is the transmitter for N2v retraction phase interneurons of the Lymnaea feeding system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Interneurons; Lymnaea; Motor Neurons; Nerve Net; Quisqualic Acid; Synapses | 1997 |
Glutamate-stimulated production of inositol phosphates is mediated by Ca2+ influx in oligodendrocyte progenitors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Glutamic Acid; Inositol Phosphates; Kainic Acid; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stem Cells | 1997 |
N18-RE-105 cells: differentiation and activation of p53 in response to glutamate and adriamycin is blocked by SV40 large T antigen tsA58.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antigens, Polyomavirus Transforming; Antiporters; Apoptosis; Cell Differentiation; Cystine; Doxorubicin; Etoposide; Excitatory Amino Acid Agonists; Glutamic Acid; Homocysteine; Hybrid Cells; Mice; Neurites; Neuroblastoma; Neurons; Neurotoxins; Rats; Rats, Inbred F344; Retina; Temperature; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biological Transport; Calcium; Cells, Cultured; Cerebral Cortex; Cycloleucine; Glutamic Acid; Hippocampus; In Vitro Techniques; Prostaglandins; Rats; Receptors, AMPA; Receptors, Glutamate; Visual Cortex | 1998 |
Increase of the intracellular Ca2+ concentration mediated by transport of glutamate into rat hippocampal synaptosomes: characterization of the activated voltage sensitive Ca2+ channels.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Glutamic Acid; Hippocampus; Kainic Acid; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Rats; Rats, Wistar; Receptors, Glutamate; Spider Venoms; Synaptosomes | 1998 |
AMPA receptors are coupled to the nitric oxide/cyclic GMP pathway in cerebellar astroglial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Cobalt; Cyclic GMP; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1997 |
Activation of NMDA and non-NMDA receptors by L-aspartate in the suprachiasmatic nucleus of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Excitatory Amino Acid Agonists; Female; Glutamic Acid; In Vitro Techniques; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 1998 |
Activity-dependent scaling of quantal amplitude in neocortical neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Cells, Cultured; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Membrane Potentials; Neuronal Plasticity; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin; Visual Cortex | 1998 |
Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Brain Ischemia; Cell Death; Cells, Cultured; Glutamic Acid; Growth Substances; Hypoxia; Kainic Acid; Male; Mice; Microinjections; Oligodendroglia; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Signal Transduction; Time Factors | 1998 |
Ethanol modulates N-methyl-D-aspartate-evoked arachidonic acid release from neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Glutamic Acid; Mice; N-Methylaspartate; Neurons | 1997 |
Networks of coactive neurons in developing layer 1.
Topics: Acetylcholine; Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Muscimol; N-Methylaspartate; Neurons; Neurotransmitter Agents; Norepinephrine; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin; Time Factors | 1998 |
Long-term potentiation and dual-component quantal signaling in the dentate gyrus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Dizocilpine Maleate; Evoked Potentials; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Long-Term Potentiation; Perforant Pathway; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses | 1998 |
Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arcuate Nucleus of Hypothalamus; Complement C7; Excitatory Amino Acid Agonists; Female; Galanin; Glutamic Acid; GTP-Binding Proteins; Male; Neural Inhibition; Neuropeptides; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Spider Venoms; Substance P; Synaptic Transmission | 1998 |
Interleukin-1 beta and interleukin-1 receptor antagonist do not affect glutamate release or calcium entry in rat striatal synaptosomes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Chelating Agents; Corpus Striatum; Egtazic Acid; Glutamates; Glutamic Acid; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Ion Transport; Male; Membrane Potentials; Nerve Degeneration; Neurotoxins; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sialoglycoproteins; Synaptosomes | 1998 |
Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Drug Synergism; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Macaca fascicularis; Male; N-Methylaspartate; Thalamic Nuclei | 1998 |
Effect of glutamate receptor agonists on catecholamine secretion in bovine chromaffin cells.
Topics: Adrenal Medulla; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nicotine; Receptors, Glutamate | 1998 |
AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Channel Blockers; Cell Death; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Homeostasis; Humans; Kainic Acid; Membrane Potentials; Neurons; Neurotoxins; Nimodipine; Potassium; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Spider Venoms | 1998 |
Glutamate-stimulated neuropeptide Y mRNA expression in the rat dentate gyrus: a prominent role of metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Injections; Injections, Intraperitoneal; Male; N-Methylaspartate; Neuropeptide Y; Neuropeptides; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger | 1998 |
Changes in GluR4 expression induced by metabotropic receptor activation in radial glia cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Chick Embryo; Cycloleucine; Glutamic Acid; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Polymerase Chain Reaction; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Retina; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1998 |
Desensitization of AMPA receptors on horizontal cells isolated from crucian carp retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Drug Tolerance; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; Kainic Acid; Patch-Clamp Techniques; Receptors, AMPA; Retina | 1998 |
Characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive component of glutamate neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cycloleucine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Fluorescent Dyes; Glutamic Acid; Humans; Hypothermia, Induced; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Neurotoxins; Synapses | 1998 |
Selective modulation of GABAA receptors by aluminum.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aluminum; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons, Afferent; Olfactory Bulb; Patch-Clamp Techniques; Rats; Receptors, GABA-A; Receptors, Glutamate; Smell | 1998 |
Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Hippocampus; N-Methylaspartate; Nerve Growth Factors; Neurotrophin 3; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Bumetanide; Carrier Proteins; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agents; Gene Expression Regulation; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Neuroblastoma; Neurons; Potassium; Receptors, Glutamate; Sodium-Potassium-Chloride Symporters; Tumor Cells, Cultured | 1998 |
The cerebral metabolic effects of manipulating glutamatergic systems within the basal forebrain in conscious rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Blood Glucose; Body Temperature; Brain Chemistry; Excitatory Amino Acid Agonists; Glucose; Glutamic Acid; Hemodynamics; Ibotenic Acid; Isoquinolines; Male; Prosencephalon; Rats; Stereotaxic Techniques | 1998 |
Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Interleukin-1; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Interleukin-1; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins | 1998 |
Activity-dependent modulation of glutamate receptors by polyamines.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cells, Cultured; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Ion Channel Gating; Ions; Kainic Acid; Kidney; Kinetics; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Phenols; Polyamines; Receptors, AMPA; Receptors, Kainic Acid; Spermidine; Spermine | 1998 |
Supraoptic oxytocin and vasopressin neurones show differential sensitivity to the neurosteroid pregnenolone sulphate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; N-Methylaspartate; Neurons; Oxytocin; Pregnenolone; Rats; Rats, Wistar; Supraoptic Nucleus; Vasopressins | 1998 |
GABA(A) receptor modulates the activity of inner hair cell afferents in guinea pig cochlea.
Topics: Acetylcholine; Action Potentials; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Baclofen; Bicuculline; Cochlea; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Muscimol; N-Methylaspartate; Receptors, GABA-A | 1998 |
Conformational changes of the smooth endoplasmic reticulum are facilitated by L-glutamate and its receptors in rat Purkinje cells.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apnea; Bradycardia; Calcium Signaling; Cycloleucine; Dendrites; Endoplasmic Reticulum, Smooth; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia, Brain; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Respiration | 1998 |
Pharmacological properties of homomeric and heteromeric GluR1o and GluR3o receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baculoviridae; Binding, Competitive; Blotting, Western; Glutamic Acid; Glycosylation; Mutagenesis; Radioligand Assay; Receptors, AMPA; Recombinant Proteins; Spodoptera | 1998 |
Taurine, glutamate and GABA modulate the outgrowth from goldfish retinal explants and its concentrations are affected by the crush of the optic nerve.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Culture Techniques; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Goldfish; N-Methylaspartate; Neurites; Optic Nerve; Retina; Taurine | 1998 |
Glutamatergic induction of CREB phosphorylation and Fos expression in primary cultures of the suprachiasmatic hypothalamus in vitro is mediated by co-ordinate activity of NMDA and non-NMDA receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cricetinae; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Gene Expression; Genes, fos; Glutamic Acid; Kainic Acid; Male; Mesocricetus; N-Methylaspartate; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 1999 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Culture Techniques; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
AMPA receptor activation of area postrema neurons.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cerebral Ventricles; Cytosol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Osmolar Concentration; Quinoxalines; Rats; Receptors, AMPA | 1999 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Excitatory amino acid responses in relay neurons of the rat lateral geniculate nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Concanavalin A; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Geniculate Bodies; Glutamic Acid; Glycine; Ionophores; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Nystatin; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
Multiple types of spontaneous excitatory synaptic currents in salamander retinal ganglion cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Animals; Convulsants; Darkness; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kinetics; Larva; N-Methylaspartate; Patch-Clamp Techniques; Photic Stimulation; Picrotoxin; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Strychnine; Synapses; Synaptic Vesicles | 1999 |
Activation of excitatory amino acid receptors in bovine dental pulp evokes the release of iCGRP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Cattle; Dental Pulp; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurogenic Inflammation; Neurons, Afferent; Nociceptors; Radioimmunoassay; Receptors, Glutamate; Statistics, Nonparametric | 1999 |
Analyses of taste nerve responses with special reference to possible receptor mechanisms of umami taste in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chorda Tympani Nerve; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Inosine Monophosphate; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Potassium; Propionates; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Taste | 1999 |
Mature hippocampal astrocytes exhibit functional metabotropic and ionotropic glutamate receptors in situ.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; omega-Conotoxins; Peptides; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; S100 Proteins; Tetrodotoxin | 1999 |
Ionotropic glutamate receptors in isolated horizontal cells of the rabbit retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1999 |
Excitatory amino acids and synaptic transmission in embryonic rat brainstem motoneurons in organotypic culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Coculture Techniques; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Organ Culture Techniques; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Miniature synaptic events maintain dendritic spines via AMPA receptor activation.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Botulinum Toxins; Dendrites; Denervation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Receptors, AMPA; Synapses; Tetrodotoxin | 1999 |
Calcium signals in cell lines derived from the cerebral cortex of normal and trisomy 16 mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Cell Line, Transformed; Cerebral Cortex; Chromosomes, Human, Pair 16; Fetus; Glutamic Acid; Humans; Intracellular Membranes; Kainic Acid; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Osmolar Concentration; Receptors, Glutamate; Reference Values; Trisomy | 1999 |
Mapping glutamatergic drive in the vertebrate retina with a channel-permeant organic cation.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Artifacts; Biological Transport; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Immunohistochemistry; In Vitro Techniques; Kainic Acid; Male; Models, Biological; Models, Molecular; N-Methylaspartate; Neurons; Rabbits; Retina; Retinal Ganglion Cells | 1999 |
Dopamine depresses glutamatergic synaptic transmission in the rat parabrachial nucleus in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Mianserin; Neurons; Patch-Clamp Techniques; Phentolamine; Pons; Quinpirole; Rats; Rats, Sprague-Dawley; Reaction Time; Sulpiride; Synaptic Transmission | 1999 |
BIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Batrachotoxins; Benzodiazepines; Cell Membrane; Cells, Cultured; Cerebral Cortex; Electroshock; Embryo, Mammalian; Glutamic Acid; In Vitro Techniques; Ischemic Attack, Transient; Male; Mexiletine; Mice; Neurons; Neuroprotective Agents; Oxadiazoles; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Channel Blockers; Sodium Channels; Synaptosomes; Veratridine | 1999 |
A high-affinity presynaptic kainate-type glutamate receptor facilitates glutamate exocytosis from cerebral cortex nerve terminals (synaptosomes).
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Exocytosis; Glutamic Acid; Kainic Acid; Male; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Synaptosomes | 1999 |
Modulation of the mesolimbic dopamine system by glutamate: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Binding, Competitive; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Limbic System; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 1999 |
N-methyl-D-aspartate receptor agonists modulate homocysteine-induced developmental abnormalities.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Cycloserine; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Homocysteine; N-Methylaspartate; Nervous System; Nervous System Malformations; Receptors, N-Methyl-D-Aspartate; Teratogens | 1999 |
Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Signaling; Cyclooxygenase Inhibitors; Eicosanoids; Excitatory Amino Acid Agonists; Glutamic Acid; Indomethacin; Iontophoresis; Male; N-Methylaspartate; Neurons, Afferent; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Substance P | 1999 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Metabotropic glutamate receptors group I are involved in cochlear neurotransmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Indans; Methoxyhydroxyphenylglycol; N-Methylaspartate; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Glutamate triggers preferential Zn2+ flux through Ca2+ permeable AMPA channels and consequent ROS production.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fluorometry; Glutamic Acid; Image Processing, Computer-Assisted; In Vitro Techniques; Mice; Neurons; Phenanthridines; Reactive Oxygen Species; Receptors, AMPA; Zinc | 1999 |
Oligomerization and ligand-binding properties of the ectodomain of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunit GluRD.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies, Monoclonal; Binding Sites; Centrifugation, Density Gradient; Chromatography, Gel; Cross-Linking Reagents; Dimerization; Excitatory Amino Acid Agonists; Glutamic Acid; Glutaral; Kinetics; Peptide Fragments; Precipitin Tests; Protein Binding; Protein Conformation; Rats; Receptors, AMPA; Receptors, Glutamate; Recombinant Proteins | 1999 |
Effect of divalent cations on AMPA-evoked extracellular alkaline shifts in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Bicarbonates; Cadmium; Calcium; Cations, Divalent; Egtazic Acid; Electrophysiology; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Nickel; Rats; Rats, Long-Evans | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Correlation of glutamate-induced apoptosis with caspase activities in cultured rat cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Caspase 1; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Chromatin; Cycloleucine; Cysteine Proteinase Inhibitors; Embryo, Mammalian; Enzyme Precursors; Excitatory Amino Acid Agonists; Glutamic Acid; Kinetics; L-Lactate Dehydrogenase; Neurons; Rats; Time Factors | 1999 |
The ontogeny of glutamate receptors and D-aspartate binding sites in the ovine CNS.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Embryonic and Fetal Development; Fetus; Glutamic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Sheep | 1999 |
Locomotor activity and accumbens Fos expression driven by ventral hippocampal stimulation require D1 and D2 receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Benzazepines; Brain Chemistry; Cycloleucine; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Excitatory Amino Acid Agonists; Genes, Immediate-Early; Glutamic Acid; Haloperidol; Hippocampus; Kainic Acid; Lidocaine; Locomotion; Male; N-Methylaspartate; Neural Pathways; Neuroprotective Agents; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1999 |
GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Excitatory Amino Acid Agonists; Gene Expression; GluK2 Kainate Receptor; Glutamic Acid; Hippocampus; Ion Channel Gating; Isoxazoles; Kainic Acid; Neurons; Propionates; Protein Structure, Tertiary; Rats; Receptors, Kainic Acid; RNA, Messenger; Structure-Activity Relationship | 2000 |
AMPA exposures induce mitochondrial Ca(2+) overload and ROS generation in spinal motor neurons in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Buffers; Calcium; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mitochondria; Motor Neurons; Neurotoxins; Phenanthridines; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Spinal Cord | 2000 |
AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Concanavalin A; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Microglia; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 2000 |
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Calcium; Cells, Cultured; Cyclic N-Oxides; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Free Radicals; Glutamic Acid; Homeostasis; Humans; Imidazoles; Lipid Peroxidation; Mice; Mice, Transgenic; Mitochondria; Motor Neuron Disease; Motor Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Oxidative Stress; Rhodamine 123; Spinal Cord; Superoxide Dismutase; Superoxides; Vitamin E | 1999 |
Glutamate and GABA activate different receptors and Cl(-) conductances in crab peptide-secretory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brachyura; Cells, Cultured; Chloride Channels; Chlorides; Concanavalin A; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quisqualic Acid; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate | 2000 |
Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channel Blockers; Cycloleucine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Lumbosacral Region; Motor Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spider Venoms; Spinal Cord | 2000 |
Cholecystokinin (CCK) increases GABA release in the rat anterior nucleus accumbens via CCK(B) receptors located on glutamatergic interneurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholecystokinin; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stimulation, Chemical; Tetrodotoxin | 2000 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Intracellular survival pathways against glutamate receptor agonist excitotoxicity in cultured neurons. Intracellular calcium responses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cerebellum; Excitatory Amino Acid Agonists; Exocytosis; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Potassium; Rats; Receptors, Glutamate | 1999 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Effects of dalargin on excitation induced by L-glutamate agonists in the frog vestibular organs.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dendrites; Electrophysiology; Enkephalin, Leucine-2-Alanine; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons, Afferent; Rana temporaria; Receptors, Opioid; Synapses; Vestibule, Labyrinth | 2000 |
Brain-derived neurotrophic factor acutely inhibits AMPA-mediated currents in developing sensory relay neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biological Transport; Brain-Derived Neurotrophic Factor; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Microscopy, Confocal; Neuronal Plasticity; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Solitary Nucleus; Synaptic Transmission | 2000 |
Control of synaptic depression by glutamate transporters.
Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission | 2000 |
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Calcium; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Embryo, Mammalian; Glutamic Acid; Homeostasis; Kinetics; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha | 2000 |
Human Bcl-2 protects against AMPA receptor-mediated apoptosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; DNA; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Genotype; Glutamic Acid; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Microscopy, Fluorescence; Necrosis; Neocortex; Neurons; Neurotoxins; Oxidants; Proto-Oncogene Proteins c-bcl-2; Receptors, AMPA; Staurosporine | 2000 |
Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Chlorides; Cycloleucine; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Neurons; Picrotoxin; Retina; Strychnine; Zebrafish | 2000 |
Differential effect of beta-N-oxalylamino-L-alanine, the Lathyrus sativus neurotoxin, and (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate on the excitatory amino acid and taurine levels in the brain of freely moving rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Brain; Corpus Striatum; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Microdialysis; Motor Cortex; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Taurine; Tetrodotoxin | 2000 |
Regional and selective effects of oestradiol and progesterone on NMDA and AMPA receptors in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Corpus Striatum; Dentate Gyrus; Estradiol; Female; Frontal Lobe; Glutamic Acid; Hippocampus; Nucleus Accumbens; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Involvement of NMDA-receptor in kainate-induced neurotoxicity in cultured fetal retinal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Retina | 2000 |
Effect of intracerebral administration of NMDA and AMPA on dopamine and glutamate release in the ventral pallidum and on motor behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Brain; Dopamine; Excitatory Amino Acid Agonists; Globus Pallidus; Glutamic Acid; Injections; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 2000 |
Biophysical properties and responses to glutamate receptor agonists of identified subpopulations of rat geniculate ganglion neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Size; Cells, Cultured; Excitatory Amino Acid Agonists; Female; Geniculate Ganglion; Glutamic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission; Taste | 2000 |
Pharmacological and molecular characterization of glutamate receptors in the MIN6 pancreatic beta-cell line.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Biological Transport; Calcium; Cell Survival; DNA Primers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Islets of Langerhans; Kainic Acid; Protein Kinase C; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms; Tumor Cells, Cultured | 2000 |
Effects of glutamate agonist versus procaine microinjections into the basal forebrain cholinergic cell area upon gamma and theta EEG activity and sleep-wake state.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Arousal; Behavior, Animal; Cholinergic Fibers; Electromyography; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microinjections; N-Methylaspartate; Neurons; Procaine; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sleep; Theta Rhythm | 2000 |
Functional role of NMDA autoreceptors in olfactory mitral cells.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoreceptors; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Nifedipine; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 2000 |
Dopamine depresses excitatory synaptic transmission onto rat subicular neurons via presynaptic D1-like dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Perforant Pathway; Presynaptic Terminals; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Sulpiride; Synaptic Transmission | 2000 |
Age-related resistance to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid-induced hippocampal lesion.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Biomarkers; Calbindins; Calcinosis; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Nerve Tissue Proteins; Neurons; Parvalbumins; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G | 2000 |
Stable expression of human homomeric and heteromeric AMPA receptor subunits in HEK293 cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Binding, Competitive; Blotting, Western; Cell Line; Electrophysiology; Glutamic Acid; Humans; Indoles; Kidney; Kinetics; Protein Subunits; Radioligand Assay; Receptors, AMPA; Sulfonamides; Transfection; Transformation, Genetic | 2000 |
Glutamate-induced production of nitric oxide in guinea pig vestibular sensory cells.
Topics: Acoustic Maculae; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fluorescein; Fluorescent Dyes; Glutamic Acid; Guinea Pigs; Hair Cells, Vestibular; Microscopy, Fluorescence; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 2000 |
Ca2+-dependent desensitization of AMPA receptors.
Topics: Adamantane; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Kainic Acid; Neurons; Nootropic Agents; Pyrrolidinones; Rats; Receptors, AMPA | 2000 |
AMPA receptor current density, not desensitization, predicts selective motoneuron vulnerability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Posterior Horn Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2000 |
Bilirubin does not modulate ionotropic glutamate receptors or glutamate transporters.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Bilirubin; Glutamic Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
In situ Ca2+ imaging reveals neurotransmitter receptors for glutamate in taste receptor cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Dextrans; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Microscopy, Confocal; N-Methylaspartate; Neurotransmitter Agents; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Taste Buds | 2000 |
Control of dendritic outputs of inhibitory interneurons in the lateral geniculate nucleus.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cats; Cycloleucine; Dendrites; GABA Antagonists; Geniculate Bodies; Glutamic Acid; In Vitro Techniques; Interneurons; Magnesium; Muscarinic Agonists; Neural Inhibition; Nicotinic Agonists; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin | 2000 |
A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Biological Transport; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Kinetics; Mice; Models, Theoretical; N-Methylaspartate; Sodium; Symporters | 2000 |
Activation of metabotropic glutamate receptors increases extracellular adenosine in vivo.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Methoxyhydroxyphenylglycol; Microdialysis; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Somatosensory Cortex | 2000 |
Glutamate-gated calcium fluxes in Arabidopsis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arabidopsis; Calcium; Egtazic Acid; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Ion Channels; Lanthanum; N-Methylaspartate | 2000 |
NBQX attenuates excitotoxic injury in developing white matter.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Male; Microinjections; Nerve Fibers, Myelinated; Neuroprotective Agents; Oligodendroglia; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate | 2000 |
AMPA receptor modulation in previously frozen mouse brain sections: opposite effects of calcium in the cortex and hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Autoradiography; Binding, Competitive; Calcium; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavanones; Flavonoids; Freezing; Glutamic Acid; Hippocampus; Mice; Neuronal Plasticity; Phospholipases A; Piperazines; Prostaglandin Antagonists; Receptors, AMPA; Tritium | 2000 |
Altered pattern of light transmittance and resistance to AMPA-induced swelling in the dentate gyrus of the epileptic hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Edema; Dentate Gyrus; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Light; Male; Membrane Potentials; Neurons; Optics and Photonics; Organ Culture Techniques; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrodotoxin | 2000 |
Contribution of cytoskeleton to the internalization of AMPA receptors.
Topics: Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytoskeleton; Depsipeptides; Endocytosis; Glutamic Acid; Hippocampus; Marine Toxins; Neurons; Peptides, Cyclic; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thiazoles; Thiazolidines; Transferrin | 2001 |
Long term depletion of serotonin leads to selective changes in glutamate receptor subunits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Dizocilpine Maleate; Fenclonine; Glutamic Acid; Male; Neuronal Plasticity; Neurons; Norepinephrine; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serotonin; Synaptic Transmission; Time Factors; Tritium | 2000 |
Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Gene Expression Regulation; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neurotoxins; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcription, Genetic | 2001 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
Dendritic glutamate-induced bursting in prefrontal pyramidal cells: role of NMDA and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Glutamic Acid; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carbon Radioisotopes; Corpus Striatum; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Microdialysis; Nootropic Agents; Potassium; Presynaptic Terminals; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tritium | 2001 |
Quinazolone-alkyl-carboxylic acid derivatives inhibit transmembrane Ca(2+) ion flux to (+)-(S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid.
Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Calcium; Calcium Channels; Cell Membrane; Cerebral Cortex; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; Ligands; Male; Models, Molecular; Molecular Structure; Piperidines; Propionates; Quinazolines; Rats; Rats, Wistar; Receptors, AMPA; Structure-Activity Relationship | 2001 |
Characterization of the glutamatergic system for induction and maintenance of allodynia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; ATP-Binding Cassette Transporters; Capsaicin; Dinoprost; Dinoprostone; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Pain Measurement; Physical Stimulation; Posterior Horn Cells; Receptors, Glutamate; Synapses; Synaptic Transmission; Touch | 2001 |
Expression and regulation of Na pump isoforms in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cerebellum; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Potassium Radioisotopes; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2001 |
Presynaptic N-methyl-D-aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Radioisotopes; Excitatory Amino Acid Agonists; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nitric Oxide; Presynaptic Terminals; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptosomes; Tritium | 2001 |
Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Benzoxazines; Cadmium Chloride; Calcium Channel Blockers; Calcium Channels, N-Type; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Organ Culture Techniques; Pertussis Toxin; Piperidines; Presynaptic Terminals; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, GABA-A; Receptors, GABA-B; Rimonabant; Synaptic Transmission; Tetrodotoxin; Virulence Factors, Bordetella | 2001 |
Inhibition of choline acetyltransferase by excitatory amino acids as a possible mechanism for cholinergic dysfunction in the central nervous system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Neurons; NG-Nitroarginine Methyl Ester; Propionates; Quisqualic Acid; Retina; Signal Transduction; Tetrodotoxin; Trifluoperazine; Verapamil | 2001 |
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides | 2001 |
Dimethyl sulfoxide suppresses NMDA- and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cells, Cultured; Dimethyl Sulfoxide; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Hippocampus; Ion Transport; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Glutamate | 2001 |
Decline in motor functions in aging is related to the loss of NMDA receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle Joint; Biomarkers; Biomechanical Phenomena; Brain Mapping; Cell Count; Dizocilpine Maleate; Dopamine; Electromyography; Female; Glutamic Acid; Learning Disabilities; Maze Learning; Movement Disorders; Muscle, Skeletal; Nerve Tissue Proteins; Pliability; Psychomotor Performance; Raclopride; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Capsaicin; Endocannabinoids; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Morpholines; Naphthalenes; Nerve Fibers; Neural Inhibition; Neurons; Patch-Clamp Techniques; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Gelatinosa | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Ca2+-dependent regulation of synaptic delta2 glutamate receptor density in cultured rat Purkinje neurons.
Topics: Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calpain; Cells, Cultured; Cerebellum; Cycloleucine; Dendrites; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Intracellular Fluid; Neuroprotective Agents; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Synaptic Membranes; Synaptic Transmission | 2001 |
Glutamate, NMDA, and AMPA induced changes in extracellular space volume and tortuosity in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Chelating Agents; Diffusion; Dizocilpine Maleate; Edema; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Gliosis; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Spinal Cord | 2001 |
Muscarinic activation of inwardly rectifying K(+) conductance reduces EPSPs in rat hippocampal CA1 pyramidal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cholinergic Agents; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gallamine Triethiodide; Glutamic Acid; Hippocampus; Muscarinic Antagonists; Nicotinic Antagonists; Organ Culture Techniques; Parasympatholytics; Patch-Clamp Techniques; Pirenzepine; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptors, Muscarinic; Stimulation, Chemical | 2001 |
AMPA-evoked acetylcholine release from cultured spinal cord motoneurons and its inhibition by GABA and glycine.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anterior Horn Cells; Cells, Cultured; Choline; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-A; Receptors, Glycine; Strychnine; Tritium | 2001 |
The pituitary adenylate cyclase-activating polypeptide modulates glutamatergic calcium signalling: investigations on rat suprachiasmatic nucleus neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cyclic AMP; Drug Interactions; Fluorescent Dyes; Fura-2; Glutamic Acid; N-Methylaspartate; Neurons; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Suprachiasmatic Nucleus | 2001 |
Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Blood Proteins; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Vectors; Glutamic Acid; Glycine; Green Fluorescent Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred ICR; Neuroprotective Agents; Patch-Clamp Techniques; Phosphoproteins; Purkinje Cells; Receptors, AMPA; Receptors, Metabotropic Glutamate; Sindbis Virus | 2001 |
Nitric oxide produced by non-motoneuron cells enhances rat embryonic motoneuron sensitivity to excitotoxins: comparison in mixed neuron/glia or purified cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Cell Communication; Cell Differentiation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Kainic Acid; Magnesium; N-Methylaspartate; Neuroglia; Neurotoxins; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Dopamine release in the prefrontal cortex during stress is reduced by the local activation of glutamate receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dicarboxylic Acids; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Synaptic Transmission | 2001 |
Somatostatin release by glutamate in vivo is primarily regulated by AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basal Ganglia; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatostatin | 2001 |
Distance-dependent increase in AMPA receptor number in the dendrites of adult hippocampal CA1 pyramidal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dendrites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Microinjections; N-Methylaspartate; Neural Pathways; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2001 |
Na(+)-K(+)-ATPase inhibition and depolarization induce glutamate release via reverse Na(+)-dependent transport in spinal cord white matter.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Benzodiazepines; Calcium; Dicarboxylic Acids; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenic Acid; Male; Membrane Potentials; Nerve Fibers, Myelinated; Neurotransmitter Uptake Inhibitors; Ouabain; Potassium; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, AMPA; Sodium; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Thiourea | 2001 |
Magnesium decreases arterial pressure and inhibits cardiovascular responses induced by N-methyl-D-aspartate and metabotropic glutamate receptors stimulation in rostral ventrolateral medulla.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Heart Rate; Magnesium; Magnesium Chloride; Magnesium Sulfate; Male; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2001 |
Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fluorobenzenes; GABA Antagonists; Glutamic Acid; Hallucinogens; Male; Mice; Mice, Inbred BALB C; Microdialysis; Neurons; Picrotoxin; Piperidines; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sesterterpenes; Tetrodotoxin | 2001 |
Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Azoles; Brain; Carrier Proteins; CHO Cells; COS Cells; Cricetinae; Electrophysiology; Glutamic Acid; Glutamine; In Vitro Techniques; Male; Models, Molecular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Structure-Activity Relationship; Synaptosomes | 2002 |
Molecular phenotyping of retinal ganglion cells.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Count; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Image Cytometry; Immunohistochemistry; In Vitro Techniques; Male; Phenotype; Rabbits; Receptors, Glutamate; Retinal Ganglion Cells; Signal Transduction; Taurine | 2002 |
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Protein Isoforms; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines; Type C Phospholipases | 2002 |
Guanine based purines inhibit [(3)H]glutamate and [(3)H]AMPA binding at postsynaptic densities from cerebral cortex of rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; Glutamic Acid; Guanine; Guanosine Monophosphate; Guanosine Triphosphate; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Purines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glutamate; Subcellular Fractions; Synaptic Membranes | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Survival signaling and selective neuroprotection through glutamatergic transmission.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Corpus Striatum; Cytoprotection; Cytoskeleton; Dioxoles; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; NF-kappa B; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Stimulation, Chemical | 2002 |
Glutamate receptor desensitization block potentiates the stimulated GABA release through external Ca2+-independent mechanisms from granule cells of olfactory bulb.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Kinetics; Male; N-Methylaspartate; Neurons; Olfactory Bulb; Potassium Chloride; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2001 |
Different action of memantine and caroverine on glutamatergic transmission in the mammalian cochlea.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Dopamine Agents; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Memantine; N-Methylaspartate; Neurons, Afferent; Quinoxalines | 2002 |
Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Lanthanum; Neurotoxins; Nifedipine; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 2002 |
NMDA and AMPA/kainate glutamatergic agonists increase the extracellular concentrations of GABA in the prefrontal cortex of the freely moving rat: modulation by endogenous dopamine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurons; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation | 2002 |
Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Arterioles; Carbon Monoxide; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heme Oxygenase (Decyclizing); Isoxazoles; Mesoporphyrins; Metalloporphyrins; Propionates; Protoporphyrins; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Swine; Vasodilation | 2002 |
Expression of AMPA/kainate receptors during development of chick embryo retina cells: in vitro versus in vivo studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Differentiation; Chick Embryo; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; GluK2 Kainate Receptor; Glutamic Acid; Immunohistochemistry; Kainic Acid; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Retina; Spheroids, Cellular; Synapses; Synaptic Transmission | 2002 |
Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Hypoglycemic Agents; Immunoblotting; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Phenformin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Spinal cord heme oxygenase participates in glutamate-induced pain-related behaviors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cyclic GMP; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Heme Oxygenase (Decyclizing); In Vitro Techniques; Injections, Spinal; Male; Mesoporphyrins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Protoporphyrins; Spinal Cord | 2002 |
Glutamate cascade to cAMP response element-binding protein phosphorylation in cultured striatal neurons through calcium-coupled group I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Drug Interactions; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Phosphorylation; Rats; Receptors, Metabotropic Glutamate; Type C Phospholipases | 2002 |
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membrane; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Kainic Acid; Male; Molsidomine; N-Methylaspartate; Nerve Degeneration; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Quinolinic Acid; Quisqualic Acid; Rats; Rats, Wistar; Tritium | 2002 |
Facilitation of glutamate release by ionotropic glutamate receptors in osteoblasts.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Division; Cells, Cultured; Glutamic Acid; Kainic Acid; N-Methylaspartate; Osteoblasts; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; Skull | 2002 |
Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Anti-Anxiety Agents; Asphyxia Neonatorum; Behavior, Animal; Benzodiazepines; Cell Death; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Movement Disorders; Neostriatum; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Synaptic Transmission | 2002 |
Carbon monoxide and metabotropic glutamate receptors in rat nucleus tractus solitarii: participation in cardiovascular effect.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Carbon Monoxide; Cardiovascular System; Cycloleucine; Deuteroporphyrins; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Heme Oxygenase (Decyclizing); Hemin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Solitary Nucleus | 2002 |
Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Calcium; Calmodulin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Feedback; Female; Glutamic Acid; Imidazoles; Imines; Isoenzymes; Isoproterenol; Isoquinolines; Kainic Acid; Male; Mice; N-Methylaspartate; Nerve Tissue Proteins; Propranolol; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Presynaptic; Second Messenger Systems; Sulfonamides; Synaptic Transmission; Trifluoperazine | 2003 |
Neurokinin release in the rat nucleus of the solitary tract via NMDA and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; N-Methylaspartate; Neurokinin A; Neurokinin B; Presynaptic Terminals; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Solitary Nucleus; Substance P; Synaptic Transmission; Vagus Nerve; Visceral Afferents | 2002 |
Glutamatergic and serotonergic mechanisms in the dorsal facial area for common carotid artery blood flow control in the cat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Blood Flow Velocity; Blood Pressure; Carotid Artery, Common; Cats; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Glutamates; Glutamic Acid; Heart Rate; Ketanserin; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, AMPA; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Crystallography, X-Ray; Glutamic Acid; Ion Channel Gating; Ligands; Methionine; Oocytes; Patch-Clamp Techniques; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quisqualic Acid; Rats; Receptors, AMPA; Solvents; Structure-Activity Relationship; Xenopus laevis | 2002 |
Involvement of acetylated tubulin in the regulation of Na+,K+ -ATPase activity in cultured astrocytes.
Topics: Acetylation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Ionophores; Mice; Monensin; N-Methylaspartate; Sodium-Potassium-Exchanging ATPase; Tubulin | 2003 |
Glutamate modulation of GABA transport in retinal horizontal cells of the skate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carrier Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Glutamic Acid; Intracellular Membranes; Kainic Acid; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Patch-Clamp Techniques; Retina; Skates, Fish | 2003 |
Rational design, synthesis, and pharmacological evaluation of 2-azanorbornane-3-exo,5-endo-dicarboxylic acid: a novel conformationally restricted glutamic acid analogue.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aza Compounds; Dicarboxylic Acids; Glutamic Acid; Inhibitory Concentration 50; Kainic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Mimicry; Molecular Structure; Norbornanes; Receptors, Glutamate; Stereoisomerism; Structure-Activity Relationship | 2003 |
Mechanism of the distance-dependent scaling of Schaffer collateral synapses in rat CA1 pyramidal neurons.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Computer Simulation; Dendrites; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; Glutamic Acid; Hippocampus; Indoles; Kinetics; Kynurenic Acid; Neurotransmitter Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2003 |
Alpha 2 adrenoceptor-mediated presynaptic inhibition of primary afferent glutamatergic transmission in rat substantia gelatinosa neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neural Inhibition; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substantia Gelatinosa; Synaptic Transmission | 2003 |
Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Autoantibodies; Base Sequence; Cell Adhesion; Cell Membrane; Chemotaxis, Leukocyte; Clone Cells; Epitopes, T-Lymphocyte; Female; Fibronectins; Glutamic Acid; Humans; Immunoglobulin G; Integrins; Jurkat Cells; Kainic Acid; Laminin; Mice; Molecular Sequence Data; Rats; Rats, Inbred Lew; Receptors, AMPA; RNA, Messenger; T-Lymphocyte Subsets; Tumor Cells, Cultured | 2003 |
Enflurane decreases glutamate neurotransmission to spinal cord motor neurons by both pre- and postsynaptic actions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Axons; Enflurane; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord; Synaptic Transmission | 2003 |
Ethanol withdrawal hyper-responsiveness mediated by NMDA receptors in spinal cord motor neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic AMP-Dependent Protein Kinases; Ethanol; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance Withdrawal Syndrome | 2003 |
Regional specific increases of [3H]AMPA binding and mRNA expression of AMPA receptors in the brain of mu-opioid receptor knockout mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain; Gene Expression; Glutamic Acid; Mice; Mice, Knockout; Neurons; Opioid Peptides; Receptors, AMPA; Receptors, Opioid, mu; RNA, Messenger; Synaptic Transmission; Tritium; Up-Regulation | 2003 |
Intracellular calcium release resulting from mGluR1 receptor activation modulates GABAA currents in wide-field retinal amacrine cells: a study with caffeine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Animals; Anticoagulants; Bicuculline; Caffeine; Calcium; Calcium Channels; Carps; Cells, Cultured; Central Nervous System Stimulants; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heparin; Immunohistochemistry; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Kainic Acid; Membrane Potentials; Methoxyhydroxyphenylglycol; Organophosphorus Compounds; Patch-Clamp Techniques; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Retina; Ryanodine | 2003 |
The effect of 6-hydroxydopamine lesions on the release of amino acids in the direct and indirect pathways of the basal ganglia: a dual microdialysis probe analysis.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Injections, Intraventricular; Kainic Acid; Male; Microdialysis; Models, Animal; Oxidopamine; Parkinson Disease; Potassium; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 2003 |
Functional analysis of Caenorhabditis elegans glutamate receptor subunits by domain transplantation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Line; Chemical Phenomena; Chemistry, Physical; Egtazic Acid; Electric Conductivity; Embryo, Mammalian; Embryo, Nonmammalian; Female; Gene Expression; Glutamic Acid; Humans; Hydrogen Bonding; Ion Channels; Kainic Acid; Kidney; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Subunits; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Recombinant Fusion Proteins; Recombinant Proteins; Structure-Activity Relationship; Transfection; Xenopus laevis | 2003 |
Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Cerebellar Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Kainic Acid; Ligands; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Substrate Specificity | 2003 |
Hyperpolarization-activated (I(h)) conductances affect brainstem auditory neuron excitability.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Perception; Brain Stem; Cochlear Nerve; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channels; Male; Neurons; Olivary Nucleus; Pyrimidines; Rats; Rats, Long-Evans; Time Factors | 2003 |
Temporal shaping of phasic neuronal responses by GABA- and non-GABA-mediated mechanisms in the somatosensory thalamus of the rat.
Topics: Action Potentials; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Neural Inhibition; Neurons; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Touch; Ventral Thalamic Nuclei; Vibrissae | 2003 |
GABA and glutamate receptors are involved in modulating pacemaker activity in hydra.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Culture Techniques; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hydra; Kainic Acid; Quinoxalines; Receptors, GABA; Receptors, Glutamate | 2003 |
Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carrier Proteins; Cell Membrane; Chronic Disease; Cytoskeletal Proteins; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hyperalgesia; Male; N-Ethylmaleimide-Sensitive Proteins; Neuralgia; Nuclear Proteins; Pain Threshold; Peptides; Peripheral Nervous System Diseases; Protein Binding; Protein Subunits; Protein Transport; Rats; Rats, Wistar; Receptors, AMPA; Recombinant Fusion Proteins; Reflex; RNA, Messenger; Synaptic Transmission; Vesicular Transport Proteins | 2003 |
Distinct quantal features of AMPA and NMDA synaptic currents in hippocampal neurons: implication of glutamate spillover and receptor saturation.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dendrites; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Membrane Potentials; Models, Neurological; Models, Statistical; N-Methylaspartate; Pyramidal Cells; Quantum Theory; Rats; Rats, Wistar; Synaptic Transmission | 2003 |
Dual roles in feeding for AMPA/kainate receptors: receptor activation or inactivation within distinct hypothalamic regions elicits feeding behavior.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Glutamic Acid; Hypothalamic Area, Lateral; Hypothalamus; Male; Neural Pathways; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Transmission | 2003 |
Effect of excess extracellular glutamate on dendrite growth from cerebral cortical neurons at 3 days in vitro: Involvement of NMDA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Embryo, Mammalian; Excitatory Amino Acid Agonists; Extracellular Fluid; Glutamic Acid; Immunohistochemistry; Mice; Mice, Inbred BALB C; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2003 |
Neurons derived from embryonic stem (ES) cells resemble normal neurons in their vulnerability to excitotoxic death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Cell Lineage; Cell Survival; Cells, Cultured; Coculture Techniques; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Glutamic Acid; Immunohistochemistry; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stem Cells | 2003 |
Dynamics of Ca(2+) and Na(+) in the dendrites of mouse cerebellar Purkinje cells evoked by parallel fibre stimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Fluorescent Dyes; Glutamic Acid; Glycine; In Vitro Techniques; Iontophoresis; Male; Mice; omega-Conotoxin GVIA; Patch-Clamp Techniques; Purkinje Cells; Ryanodine; Sodium; Stimulation, Chemical; Tetrodotoxin; Time Factors | 2003 |
Role of astrocytes in depolarization-coupled release of glutamate in cerebellar cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebellum; Glutamic Acid; Mice; Nocodazole | 2004 |
Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cell Line; Cells, Cultured; Cerebral Cortex; Endocytosis; Glutamic Acid; Humans; Neuronal Plasticity; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Synapses; Xenopus laevis | 2004 |
Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Cellular Senescence; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Eye Proteins; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Picrotoxin; Receptors, AMPA; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Taurine | 2004 |
AMPA, not NMDA, activates RhoA GTPases and subsequently phosphorylates moesin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Line; Excitatory Amino Acid Agonists; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kainic Acid; Microfilament Proteins; N-Methylaspartate; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; rho-Associated Kinases; rhoA GTP-Binding Protein | 2004 |
Chemistry and conformation of the ligand-binding domain of GluR2 subtype of glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Crystallography, X-Ray; Cysteine; Disulfides; Glutamic Acid; Humans; Hydrogen Bonding; Kainic Acid; Ligands; Molecular Conformation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Glutamate; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Water | 2004 |
Extracellular taurine in the substantia nigra: taurine-glutamate interaction.
Topics: Adrenergic Agents; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Chemistry; Calcium; Chelating Agents; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Excitatory Amino Acid Antagonists; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Ketamine; Male; Membrane Potentials; Microdialysis; N-Methylaspartate; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Substantia Nigra; Taurine; Time Factors; Zinc | 2004 |
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Administration Routes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Glutamic Acid; Hindlimb; Kainic Acid; Lumbosacral Region; Male; Microdialysis; Motor Neurons; N-Methylaspartate; Paralysis; Perfusion; Potassium; Potassium Channel Blockers; Rats; Receptors, AMPA; Spinal Cord | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Central Nervous System Stimulants; Dopamine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synapses; Time Factors; Transferrin; Ventral Tegmental Area | 2004 |
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Dopamine-glutamate interactions controlling prefrontal cortical pyramidal cell excitability involve multiple signaling mechanisms.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Male; N-Methylaspartate; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction | 2004 |
Glutamate-induced elevations in intracellular chloride concentration in hippocampal cell cultures derived from EYFP-expressing mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Angiogenesis Inhibitors; Animals; Animals, Newborn; Bacterial Proteins; Benzopyrans; Bicuculline; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Furosemide; GABA Antagonists; Glutamic Acid; Hippocampus; Hydrogen-Ion Concentration; Intracellular Space; Luminescent Proteins; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Mice, Transgenic; N-Methylaspartate; Naphthols; Neurons; Nitrobenzoates; Potassium; Rhodamines; Time Factors | 2004 |
Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Bicuculline; Calbindin 2; Calcium; Calcium-Binding Proteins; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Nerve Net; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Time Factors; Valine | 2004 |
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Glutamic Acid; Ion Channel Gating; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nefopam; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Sodium Channels; Synaptic Transmission; Tritium | 2004 |
Glutamate-evoked release of adenosine and regulation of peripheral nociception.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrates; Conditioning, Psychological; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Gliosis; Glutamic Acid; Male; Microglia; Neural Inhibition; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Theophylline | 2004 |
Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CHO Cells; Chromatography, High Pressure Liquid; Circular Dichroism; Cricetinae; Crystallography, X-Ray; Electrophysiology; Glutamic Acid; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Conformation; Ovum; Rats; Receptors, Glutamate; Second Messenger Systems; Stereoisomerism; Xenopus | 2004 |
AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3-kinase-dependent activation in extracellular signal-regulated kinase to upregulate BDNF gene expression.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Brain-Derived Neurotrophic Factor; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Neurotoxins; Phosphatidylinositol 3-Kinases; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; RNA, Messenger; Signal Transduction; src-Family Kinases; Up-Regulation | 2004 |
Dissociation of [3H]L-glutamate uptake from L-glutamate-induced [3H]D-aspartate release by 3-hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylic acid and 3-hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-6-carboxylic acid, two con
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Carboxylic Acids; Cells, Cultured; Glutamic Acid; Ions; Male; Oxazoles; Rats; Synaptosomes; Tritium | 2004 |
Synaptic activity augments muscarinic acetylcholine receptor-stimulated inositol 1,4,5-trisphosphate production to facilitate Ca2+ release in hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biosensing Techniques; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Fluorescent Dyes; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Inositol 1,4,5-Trisphosphate; Microscopy, Confocal; Microscopy, Fluorescence; Neurons; Oscillometry; Picrotoxin; Plasmids; Rats; Receptors, AMPA; Receptors, Muscarinic; Synapses; Time Factors; Transfection | 2004 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
Glutamate-dependent transcriptional regulation of GLAST: role of PKC.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Arthropod Proteins; Cells, Cultured; Cerebellum; Chick Embryo; Chloramphenicol O-Acetyltransferase; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Deletion; Genes, fos; Genes, jun; Genes, Reporter; Glutamic Acid; Indoles; Invertebrate Hormones; Maleimides; Models, Biological; Neuroglia; Promoter Regions, Genetic; Protein Kinase C; Pyridines; Sequence Analysis, DNA; Staurosporine; TATA Box; Transcription, Genetic; Transfection | 2004 |
Aspartate release from rat hippocampal synaptosomes.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Aspartic Acid; Blotting, Western; Botulinum Toxins; Calcium; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Ionomycin; Ionophores; Metalloendopeptidases; Niflumic Acid; Potassium; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Spider Venoms; Synaptosomes; Tetanus Toxin; Thiourea | 2004 |
Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Amino Acids; Animals; Aspartic Acid; Dicarboxylic Acids; Drug Interactions; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 2004 |
Resistance of human adult oligodendrocytes to AMPA/kainate receptor-mediated glutamate injury.
Topics: Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Astrocytes; Blotting, Western; Brain; Calcium; Cell Survival; Cells, Cultured; Female; Glutamic Acid; Humans; Kainic Acid; Male; Middle Aged; Oligodendroglia; Rats; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity | 2004 |
Glutamate mediates acute glucose transport inhibition in hippocampal neurons.
Topics: 4-Chloro-7-nitrobenzofurazan; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biological Transport; Calcium Channels; Cells, Cultured; Deoxyglucose; Fluorescent Dyes; Glucosamine; Glucose; Glutamic Acid; Hippocampus; Monosaccharide Transport Proteins; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Channels | 2004 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cell Size; Circadian Rhythm; Cytochalasin D; Cytoskeleton; Dicarboxylic Acids; Dopamine; Eye Proteins; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; N-Methylaspartate; Neuroglia; Neurons; Nocodazole; Potassium; Pyrrolidines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Xanthenes | 2004 |
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.
Topics: Active Transport, Cell Nucleus; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Caspases; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cysteine Proteinase Inhibitors; Cytochromes c; DNA Damage; Enzyme Activation; Excitatory Amino Acid Agonists; Flavoproteins; Genes, bcl-2; Glutamic Acid; Injections; Intracellular Membranes; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Mitochondria; N-Methylaspartate; Neurons; Nitric Oxide; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Transfection | 2004 |
Nitric oxide modulation of glutamatergic, baroreflex, and cardiopulmonary transmission in the nucleus of the solitary tract.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baroreflex; Biguanides; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heart; Heart Rate; Kidney; Lung; Male; Microinjections; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Sympathetic Nervous System; Synaptic Transmission | 2005 |
Ampakine CX546 bolsters energetic response of astrocytes: a novel target for cognitive-enhancing drugs acting as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzothiadiazines; Cell Separation; Cells, Cultured; Cerebellum; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; Lactic Acid; Mice; Nootropic Agents; Piperidines; Receptors, AMPA | 2005 |
Xenon reduces glutamate-, AMPA-, and kainate-induced membrane currents in cortical neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred BALB C; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Transfection; Tumor Cells, Cultured; Xenon | 2005 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
Microsecond-to-millisecond conformational dynamics demarcate the GluR2 glutamate receptor bound to agonists glutamate, quisqualate, and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Glutamic Acid; Ligands; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quisqualic Acid; Receptors, AMPA; Thermodynamics | 2005 |
Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamic Acid; Injections, Subcutaneous; Male; Morphine; N-Methylaspartate; Nucleus Accumbens; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Tritium | 2005 |
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescence Resonance Energy Transfer; Gene Expression; Glutamic Acid; Glycine; Hippocampus; Humans; Insecta; Luminescent Proteins; Microscopy, Confocal; Molecular Biology; Mutagenesis, Site-Directed; N-Methylaspartate; Neurons; Phosphorylation; Protein Binding; Quinoxalines; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors; Transfection | 2005 |
Supraspinal and spinal alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid and N-methyl-D-aspartate glutamatergic control of the micturition reflex in the urethane-anesthetized rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Anesthetics, Intravenous; Animals; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electromyography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Injections, Intraventricular; Injections, Spinal; Isoquinolines; N-Methylaspartate; Neural Pathways; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrazoles; Urethane; Urinary Bladder; Urination | 2005 |
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness | 2005 |
Cortical glutamatergic markers in schizophrenia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; In Situ Hybridization; Kainic Acid; Male; Middle Aged; Postmortem Changes; Radioligand Assay; Receptors, Glutamate; Schizophrenia; Tritium | 2005 |
Modulation of presynaptic Ca2+ entry by AMPA receptors at individual GABAergic synapses in the cerebellum.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Cerebellum; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Microscopy, Confocal; Microscopy, Electron, Transmission; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Presynaptic Terminals; Purkinje Cells; Rats; Receptors, AMPA; Synapses; Time Factors | 2005 |
Release of endogenous glutamate by AMPA receptors expressed in cultured rat costal chondrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Chondrocytes; Female; Gene Expression Regulation; Glutamic Acid; Rats; Rats, Wistar; Receptors, AMPA; Ribs | 2005 |
Long-term potentiation of silent synapses in substantia gelatinosa neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Chelating Agents; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Magnesium; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synapses | 2005 |
Development of functional neurons from postnatal stem cells in vitro.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Differentiation; Cells, Cultured; Culture Media; Glutamic Acid; Immunohistochemistry; Microscopy, Confocal; Microtubule-Associated Proteins; Neurons; Optic Nerve; Peptide Fragments; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Purinergic P2; Receptors, Purinergic P2X; Stem Cells; Tetanus Toxin | 2005 |
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Casein Kinase 1 epsilon; Casein Kinase I; Casein Kinase Ialpha; Casein Kinase Idelta; Corpus Striatum; Egtazic Acid; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 2005 |
Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; Drug Administration Schedule; Drug Combinations; Electric Conductivity; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Membrane Proteins; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar | 2005 |
Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Interleukin-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; Neurons; Neurotoxins; Organ Culture Techniques; Receptors, AMPA; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2005 |
Inhibition of rho-kinase in the nucleus tractus solitarius enhances glutamate sensitivity in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amides; Animals; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Injections; Intracellular Signaling Peptides and Proteins; Iontophoresis; Male; N-Methylaspartate; Neurons; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Solitary Nucleus | 2005 |
Glutamate receptor-mediated effects on growth and morphology of human histiocytic lymphoma cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Proliferation; Cell Shape; Culture Media, Serum-Free; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Humans; Kainic Acid; Lymphoma, Large B-Cell, Diffuse; Microscopy, Electron; Receptors, Glutamate; Time Factors; U937 Cells | 2005 |
Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cell Survival; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Pertussis Toxin; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
Release kinetics, quantal parameters and their modulation during short-term depression at a developing synapse in the rat CNS.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Stem; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kinetics; N-Methylaspartate; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles | 2005 |
Inhibitory glutamate receptors in spider peripheral mechanosensory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; beta-Alanine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Excitatory Amino Acid Agonists; GABA Agonists; Glutamic Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Muscimol; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Physical Stimulation; Receptors, Glutamate; Sense Organs; Spiders | 2005 |
Electrophysiological properties of human hypothalamic hamartomas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Bicuculline; Cadmium Chloride; Child; Child, Preschool; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Glutamic Acid; Hamartoma; Humans; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Infant; Isoenzymes; Kainic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Phosphopyruvate Hydratase; Potassium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Valine | 2005 |
In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability.
Topics: Adaptation, Physiological; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Denervation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Muscarinic Antagonists; Muscimol; Neural Inhibition; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Septal Nuclei; Synaptic Transmission; Taurine; Tritium | 2005 |
Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bradykinin; Drug Synergism; Glutamic Acid; Hyperalgesia; In Vitro Techniques; Mice; Mice, Knockout; N-Methylaspartate; Pain; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Spinal Cord; Synaptic Transmission | 2005 |
Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Calcium; Cannabinoids; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 4; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamic Acid; In Vitro Techniques; Long-Term Synaptic Depression; Membrane Potentials; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Patch-Clamp Techniques; Purkinje Cells; Quinoxalines; Rats; Synapses | 2005 |
Rapid control of brain aromatase activity by glutamatergic inputs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Brain; Coturnix; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate | 2006 |
Different function of pedunculopontine GABA and glutamate receptors in nucleus accumbens dopamine, pedunculopontine glutamate and operant discriminative behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Brain Chemistry; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesencephalon; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Time Factors | 2005 |
Neuroprotective effect of Chuk-Me-Sun-Dan on NMDA- and AMPA-evoked nitric oxide synthase activity in mouse brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Mice; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide Synthase; Plant Extracts; Receptors, Glutamate | 2005 |
Anatomical evidence for glutamatergic transmission in primary sensory neurons and onto postganglionic neurons controlling penile erection in rats: an ultrastructural study with neuronal tracing and immunocytochemistry.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ganglia, Spinal; Glutamic Acid; Immunohistochemistry; Lumbosacral Region; Male; Microscopy, Electron, Transmission; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission | 2006 |
Glutamatergic neurotransmission expression profiling in the mouse hippocampus after perforant-path transection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; DNA, Complementary; Down-Regulation; Gene Expression Profiling; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Immunoblotting; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nucleic Acid Amplification Techniques; Oligonucleotide Array Sequence Analysis; Perforant Pathway; Synaptic Transmission | 2005 |
Estradiol modulation of kainic acid-induced calcium elevation in neonatal hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain; Calcium; Cells, Cultured; Estradiol; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; Kainic Acid; Microscopy, Fluorescence; Neurons; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Time Factors | 2006 |
Maintenance of presynaptic function by AMPA receptor-mediated excitatory postsynaptic activity in adult brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Binding Sites; Brain; Calcium; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Motor Activity; N-Methylaspartate; Neurons; Polyvinyls; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, AMPA; Sodium; Synapses; Tetrodotoxin; Time Factors | 2005 |
Different patterns of pharmacological reinstatement of cocaine-seeking behavior between Fischer 344 and Lewis rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Extinction, Psychological; Glutamic Acid; Male; Rats; Rats, Inbred F344; Rats, Inbred Lew; Self Administration; Species Specificity | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Actions of midazolam on excitatory transmission in dorsal horn neurons of adult rat spinal cord.
Topics: Adjuvants, Anesthesia; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hypnotics and Sedatives; In Vitro Techniques; Midazolam; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons; Patch-Clamp Techniques; Rats; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 2006 |
Kynurenic acid synthesis in bovine retinal slices--effect of glutamate agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cattle; Excitatory Amino Acid Agonists; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Organ Culture Techniques; Retina | 2006 |
State-dependent dendritic computation in hippocampal CA1 pyramidal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Tetrodotoxin | 2006 |
Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Isoquinolines; Mice; Microscopy, Video; N-Methylaspartate; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Signal Transduction; Sulfonamides; Suprachiasmatic Nucleus | 2006 |
Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Benzodiazepines; Blotting, Western; Calcium; Carbachol; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Movement; Cells, Cultured; Chelating Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fibronectins; Glutamic Acid; Immunohistochemistry; Immunoprecipitation; Integrin alphaV; Ionophores; Kainic Acid; Models, Biological; Myelin Proteolipid Protein; Myelin Sheath; Oligodendroglia; Pertussis Toxin; Quinoxalines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Receptors, AMPA; Ruthenium Red; Stem Cells; Thapsigargin | 2006 |
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Thymine; Xenopus laevis | 2006 |
Serum-dependence of AMPA receptor-mediated proliferation in glioma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cattle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression; Glioma; Glutamic Acid; Humans; Quinoxalines; Rats; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Serum | 2006 |
The relationship between agonist potency and AMPA receptor kinetics.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Line; Computer Simulation; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Ion Channel Gating; Kidney; Kinetics; Membrane Potentials; Models, Biological; Quisqualic Acid; Receptors, AMPA | 2006 |
Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Neuroprotective Agents; Nociceptors; Pain; Receptors, Glutamate; Spinal Cord | 2006 |
Ionotropic glutamate receptor activation increases intracellular calcium in prolactin-releasing cells of the adenohypophysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotransformation; Blotting, Western; Calcium; Calcium Channels; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Immunohistochemistry; Ion Channel Gating; Microscopy, Confocal; Pituitary Gland, Anterior; Prolactin; Radioimmunoassay; Receptors, Glutamate; Tilapia | 2006 |
Ultrastructural localisation and differential agonist-induced regulation of AMPA and kainate receptors present at the presynaptic active zone and postsynaptic density.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Down-Regulation; Excitatory Amino Acid Agonists; Glutamic Acid; Microscopy, Electron, Transmission; N-Methylaspartate; Organ Culture Techniques; Presynaptic Terminals; Protein Subunits; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Synapses; Synaptic Membranes; Synaptic Transmission; Synaptosomes; Up-Regulation | 2006 |
Brain-derived neurotrophic factor and neurotrophin receptors modulate glutamate-induced phase shifts of the suprachiasmatic nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Brain-Derived Neurotrophic Factor; Carbazoles; Circadian Rhythm; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Indole Alkaloids; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, Glutamate; Receptors, Nerve Growth Factor; Suprachiasmatic Nucleus | 2006 |
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Electrophysiology; Glutamic Acid; Humans; Mesylates; Models, Molecular; Molecular Sequence Data; Oocytes; Point Mutation; Protein Structure, Quaternary; Rats; Receptors, AMPA; Sulfhydryl Reagents; Xenopus laevis | 2006 |
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia | 2007 |
Role of the chemical interactions of the agonist in controlling alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Line; Fluorescence Resonance Energy Transfer; Glutamic Acid; Humans; Kainic Acid; Mutation, Missense; Protein Binding; Protein Conformation; Receptors, AMPA; Spectroscopy, Fourier Transform Infrared; Transfection | 2007 |
The colocalization of CGRP receptor and AMPA receptor in the spinal dorsal horn neuron of rat: a morphological and electrophysiological study.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcitonin Gene-Related Peptide; Evoked Potentials; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Glutamic Acid; Male; Nociceptors; Pain; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Calcitonin Gene-Related Peptide; Sensation; Spinal Nerve Roots; Synaptic Transmission | 2007 |
Environmental enrichment selectively increases glutamatergic responses in layer II/III of the auditory cortex of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Cortex; Auditory Perception; Electrophysiology; Environment; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Models, Neurological; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2007 |
Quantal release of ATP in mouse cortex.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Mice; Mice, Inbred C57BL; Neurons; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Glutamate; Suramin | 2007 |
Antipsychotic drugs reverse the AMPA receptor-stimulated release of 5-HT in the medial prefrontal cortex.
Topics: Adrenergic alpha-1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Male; Microdialysis; Neural Inhibition; Norepinephrine; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Synaptic Transmission; Thalamus | 2007 |
Modulation of [3H]dopamine release by glutathione in mouse striatal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Glutathione; Glutathione Disulfide; Kainic Acid; Mice; Oxidation-Reduction; Potassium; Tritium | 2007 |
AMPA-mediated excitotoxicity in oligodendrocytes: role for Na(+)-K(+)-Cl(-) co-transport and reversal of Na(+)/Ca(2+) exchanger.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Cell Death; Cells, Cultured; Central Nervous System; Excitatory Amino Acid Agonists; Glutamic Acid; Membrane Transport Proteins; Mitochondria; Neurotoxins; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2007 |
The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Drug Interactions; Enzyme Inhibitors; ErbB Receptors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neuregulin-1; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinazolines; Rats; Receptor, ErbB-4; RNA Interference; RNA, Small Interfering; Synapses; Synaptic Transmission; Transfection; Tyrphostins | 2007 |
The role of defensins in the excitability of the peripheral vestibular system in the frog: evidence for the presence of communication between the immune and nervous systems.
Topics: Acetylcholine; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Defensins; Animals; Atropine; Cholinergic Antagonists; Cycloleucine; Defensins; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Immune System; In Vitro Techniques; Inflammation; Kainic Acid; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuroimmunomodulation; Neurons, Afferent; Rabbits; Rana temporaria; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Opioid; Semicircular Canals; Synaptic Transmission; Vestibule, Labyrinth | 2007 |
Ca2+ entry via AMPA-type glutamate receptors triggers Ca2+-induced Ca2+ release from ryanodine receptors in rat spiral ganglion neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caffeine; Calcium; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Ryanodine; Ryanodine Receptor Calcium Release Channel; Spiral Ganglion | 2008 |
Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Brain Damage, Chronic; Brain Ischemia; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Genetic Predisposition to Disease; Glutamic Acid; Hypertension; Ion Channel Gating; Male; Membrane Potentials; Nerve Degeneration; Neurotoxins; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, AMPA; Regional Blood Flow; Vascular Resistance | 2007 |
alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3beta.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ischemia; Caspase 3; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Nerve Degeneration; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Receptors, AMPA; Reperfusion Injury; Signal Transduction; Time Factors | 2008 |
Glutamate mediates platelet activation through the AMPA receptor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Platelets; Glutamic Acid; Humans; In Vitro Techniques; Ion Transport; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Knockout; Platelet Activation; Receptors, AMPA; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium; Thrombosis | 2008 |
Bis(7)-tacrine prevents glutamate-induced excitotoxicity more potently than memantine by selectively inhibiting NMDA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cytoprotection; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Memantine; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tacrine | 2008 |
NMDA and GABA B receptors are involved in controlling nematocyst discharge in hydra.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Drug; Epinephrine; Glutamic Acid; Glycine; Hydra; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Receptors, GABA-B; Serotonin | 2008 |
Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Male; N-Methylaspartate; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Phosphorylation; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tibia; Time Factors | 2008 |
An attractor hypothesis of obsessive-compulsive disorder.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Nerve Net; Neurons; Obsessive-Compulsive Disorder; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2008 |
Serotoninergic modulation of sensory transmission to brainstem reticulospinal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lampreys; N-Methylaspartate; Neural Pathways; Receptors, Glutamate; Reticular Formation; Serotonin; Spinal Cord; Synaptic Transmission; Trigeminal Nerve | 2008 |
Blockade of NMDA receptors in the prefrontal cortex increases dopamine and acetylcholine release in the nucleus accumbens and motor activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinergic Antagonists; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glutamic Acid; Homovanillic Acid; Injections, Intraventricular; Male; Mecamylamine; Microinjections; Motor Activity; Muscarinic Antagonists; N-Methylaspartate; Nicotinic Antagonists; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Scopolamine | 2008 |
Neuronal pentraxins modulate cocaine-induced neuroadaptations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; C-Reactive Protein; Cocaine; Conditioning, Psychological; Crosses, Genetic; Extracellular Matrix; Gene Deletion; Glutamic Acid; Glycine; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Neurons; Receptors, AMPA; Resorcinols; Synapses | 2009 |
N-Methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involved in the induction of sedative effects under an acute stress in neonatal chicks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chickens; Excitatory Amino Acid Agonists; Glutamic Acid; Immobility Response, Tonic; Kainic Acid; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 2009 |
Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Crystallography, X-Ray; Glutamic Acid; Ligands; Protein Conformation; Receptors, AMPA | 2008 |
AMPA reduces surface expression of NR1 through regulation of GSK3beta.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Biotinylation; Calcium; Cerebral Cortex; Excitatory Amino Acid Agonists; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoblotting; Neurons; Rats; Receptors, N-Methyl-D-Aspartate | 2009 |
Blocking glutamate receptors in the waist area of the parabrachial nucleus decreases taste reactivity behaviors in conscious rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Taste | 2009 |
Estradiol suppresses glutamatergic transmission to gonadotropin-releasing hormone neurons in a model of negative feedback in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Estradiol; Excitatory Postsynaptic Potentials; Feedback, Physiological; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Neurons; Ovariectomy; Receptors, Kainic Acid; Synaptic Transmission | 2009 |
GABA(A)- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Clocks; Brain; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Lymnaea; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Picrotoxin; Receptors, AMPA; Receptors, GABA-A; Respiration | 2009 |
Protein SUMOylation modulates calcium influx and glutamate release from presynaptic terminals.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Central Nervous System Stimulants; Endopeptidases; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Wistar; Recombinant Proteins; Small Ubiquitin-Related Modifier Proteins; SUMO-1 Protein; Synaptic Transmission; Synaptosomes | 2009 |
Synaptic SAP97 isoforms regulate AMPA receptor dynamics and access to presynaptic glutamate.
Topics: Adaptor Proteins, Signal Transducing; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Glutamic Acid; Hippocampus; Membrane Proteins; Peptide Fragments; Presynaptic Terminals; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses | 2009 |
Silent synapses onto interneurons in the rat CA1 stratum radiatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Synapses | 2009 |
Moderate hypobaric hypoxia modifies Ca2+-mediated glutamatergic signal transduction in rat cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Excitatory Amino Acid Agonists; Glutamic Acid; Hypoxia; Male; N-Methylaspartate; Rats; Rats, Wistar; Signal Transduction | 2009 |
Glutamate responsiveness of medial vestibular nucleus neurons in aged rats.
Topics: Action Potentials; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; In Vitro Techniques; Male; Microelectrodes; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vestibular Nuclei | 2010 |
Glutamate controls growth rate and branching of dopaminergic axons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Calcineurin Inhibitors; Calcium; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Dopamine; Glutamic Acid; Growth Cones; Intracellular Space; Kainic Acid; Mesencephalon; Mice; Mice, Transgenic; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Ryanodine Receptor Calcium Release Channel | 2009 |
AMPA and metabotropic excitoxicity explain subplate neuron vulnerability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Glucose; Glutamic Acid; Immunoblotting; Neurons; Oligonucleotide Array Sequence Analysis; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Time Factors | 2010 |
Properties of glutamatergic synapses in immature layer Vb pyramidal neurons: coupling of pre- and postsynaptic maturational states.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Models, Neurological; Patch-Clamp Techniques; Presynaptic Terminals; Probability; Pyramidal Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses | 2010 |
Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acids; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Rats | 2010 |
Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Green Fluorescent Proteins; Humans; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Subunits; Radioligand Assay; Receptors, Kainic Acid; Structure-Activity Relationship; Time Factors; Transfection; Tritium | 2010 |
Presynaptic 5-HT(1B) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Neural Inhibition; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Septal Nuclei; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Synapses; Synaptic Transmission | 2010 |
Neuregulin beta1 enhances peak glutamate-induced intracellular calcium levels through endoplasmic reticulum calcium release in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Calcium; Calcium Signaling; Cells, Cultured; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Inositol 1,4,5-Trisphosphate Receptors; N-Methylaspartate; Neuregulin-1; Neurons; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Ryanodine; Ryanodine Receptor Calcium Release Channel; Second Messenger Systems | 2009 |
Control of cannabinoid CB1 receptor function on glutamate axon terminals by endogenous adenosine acting at A1 receptors.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzoxazines; Biophysics; CA1 Region, Hippocampal; Caffeine; Calcium Channel Blockers; Dronabinol; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Piperidines; Presynaptic Terminals; Propanolamines; Pyrazoles; Quinoxalines; Receptor, Adenosine A1; Receptor, Cannabinoid, CB1; Xanthines | 2010 |
BDNF is required for the induction of a presynaptic component of the functional conversion of silent synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cholinergic Fibers; Glutamic Acid; Long-Term Potentiation; Memory; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptor, trkB; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synapses; Synaptic Transmission | 2011 |
Dopamine modulation of excitatory currents in the striatum is dictated by the expression of D1 or D2 receptors and modified by endocannabinoids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cannabinoid Receptor Modulators; Cells, Cultured; Corpus Striatum; Dopamine; Endocannabinoids; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction; Synapses | 2010 |
Characteristics and functions of {alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors expressed in mouse pancreatic {alpha}-cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cell Size; Electrophysiology; Excitatory Amino Acid Agonists; Exocytosis; Glucagon; Glucagon-Secreting Cells; Glutamic Acid; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Kainic Acid; Male; Membrane Potentials; Mice; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Differences in glutamate-mediated calcium responses in the ventral cochlear nucleus and inferior colliculus of the developing rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Auditory Pathways; Calcium; Calcium Signaling; Cochlear Nucleus; Glutamic Acid; Inferior Colliculi; Models, Animal; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Wistar; Receptors, Glutamate | 2010 |
Involvement of AMPA/kainate-excitotoxicity in MK801-induced neuronal death in the retrosplenial cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cell Death; Cerebral Cortex; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Limbic System; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2010 |
Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Ambystoma; Animals; Calcium; Calcium Channels; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Glutamic Acid; Glycine Agents; Kainic Acid; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Neurotransmitter Agents; Patch-Clamp Techniques; Picrotoxin; Receptors, Glutamate; Retinal Ganglion Cells; Signal Transduction; Strychnine; Synaptic Transmission; Taurine | 2010 |
Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Cells, Cultured; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Lysophospholipids; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Mossy Fibers, Hippocampal; Neurons; Patch-Clamp Techniques; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar; Receptors, Lysosphingolipid; RNA, Small Interfering; Sphingosine; Synapses; Transfection | 2010 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, Reporter; Glutamic Acid; Luciferases; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; NFATC Transcription Factors; Nifedipine; Potassium; Progesterone; Rats; Rats, Sprague-Dawley | 2011 |
Acute knockdown of AMPA receptors reveals a trans-synaptic signal for presynaptic maturation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Humans; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Receptors, AMPA; Receptors, Glutamate; RNA, Small Interfering; Signal Transduction; Synapses; Synaptic Transmission | 2011 |
Glutamate-vasopressin interactions and the neurobiology of anabolic steroid-induced offensive aggression.
Topics: Age Factors; Aggression; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anabolic Agents; Animals; Animals, Newborn; Arginine Vasopressin; Behavior, Animal; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hormone Antagonists; Hypothalamic Area, Lateral; Male; Mesocricetus; Microinjections; Quinoxalines; Septal Nuclei; Statistics, Nonparametric; Steroids; Vasopressins; Vesicular Glutamate Transport Protein 2 | 2011 |
Quantifying water-mediated protein-ligand interactions in a glutamate receptor: a DFT study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Crystallography, X-Ray; Glutamic Acid; Ligands; Models, Molecular; Quantum Theory; Receptors, Glutamate; Structure-Activity Relationship; Water | 2011 |
A positive feedback synapse from retinal horizontal cells to cone photoreceptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Animals; Calcium; Calcium Signaling; Feedback, Physiological; Glutamic Acid; In Vitro Techniques; Lizards; Membrane Potentials; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Retina; Retinal Cone Photoreceptor Cells; Retinal Horizontal Cells; Synapses; Zebrafish | 2011 |
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Lysophospholipids; Male; Maleimides; Mossy Fibers, Hippocampal; Neurons; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; Suramin; Thiazoles | 2011 |
Structure and assembly mechanism for heteromeric kainate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Line, Transformed; Chromatography, Gel; Crystallography; Crystallography, X-Ray; Excitatory Amino Acid Agonists; GluK2 Kainate Receptor; Glutamic Acid; Humans; Membrane Potentials; Mice; Models, Molecular; Mutagenesis; Oocytes; Protein Structure, Tertiary; Pyrimidines; Receptors, AMPA; Receptors, Kainic Acid; Transfection; Xenopus | 2011 |
Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Catalepsy; Drug Synergism; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Membrane Potentials; Olanzapine; Oxadiazoles; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Synaptic Transmission; Tetrahydronaphthalenes | 2012 |
Photodynamic therapy leads to death of C6 glioma cells partly through AMPAR.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Death; Cell Line, Tumor; Glioma; Glutamic Acid; Humans; Photochemotherapy; Receptors, AMPA | 2012 |
Dopamine-glutamate interplay in the ventral striatum modulates spatial learning in a receptor subtype-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Basal Ganglia; Behavior, Animal; Benzazepines; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Habituation, Psychophysiologic; Learning; Male; Mice; Motor Activity; N-Methylaspartate; Quinoxalines; Receptors, Dopamine; Space Perception; Sulpiride | 2012 |
Differential effects of chronic hyperammonemia on modulation of the glutamate-nitric oxide-cGMP pathway by metabotropic glutamate receptor 5 and low and high affinity AMPA receptors in cerebellum in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Chronic Disease; Citrulline; Cyclic GMP; Glutamic Acid; Hyperammonemia; Male; Nitric Oxide; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate | 2012 |
Presynaptic inhibition of glutamate transmission by α2 receptors in the VTA.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brimonidine Tartrate; Clonidine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Mice; Neural Inhibition; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Channel Blockers; Tetrodotoxin; Ventral Tegmental Area | 2012 |
Presynaptic kainate receptor-mediated facilitation of glutamate release involves Ca2+ -calmodulin at mossy fiber-CA3 synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA3 Region, Hippocampal; Calcium; Calmodulin; Cyclic AMP; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, Kainic Acid; Synaptosomes | 2012 |
Glutamatergic input to the lateral hypothalamus stimulates ethanol intake: role of orexin and melanin-concentrating hormone.
Topics: Alcohol Drinking; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; Hypothalamic Area, Lateral; Hypothalamic Hormones; Intracellular Signaling Peptides and Proteins; Male; Melanins; N-Methylaspartate; Neuropeptides; Orexins; Pituitary Hormones; Rats; Rats, Sprague-Dawley | 2013 |
Subthalamic nucleus electrical stimulation modulates calcium activity of nigral astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Basal Metabolism; Calcium Signaling; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Substantia Nigra; Subthalamic Nucleus | 2012 |
Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Dendrites; Glutamic Acid; Glycine; Hippocampus; Microtubules; Neuronal Plasticity; Neurons; Phosphorylation; Protein Transport; Rats; Receptors, AMPA; Spine; Synapses | 2012 |
The structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Crystallography, X-Ray; Glutamic Acid; Inhibitory Concentration 50; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrroles; Rats; Receptors, AMPA | 2012 |
Inhibitory effects of acorn extract on glutamate-induced calcium signaling in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Signaling; Cells, Cultured; Glutamic Acid; Hippocampus; N-Methylaspartate; Plant Extracts; Quercus; Rats; Rats, Sprague-Dawley | 2013 |
Expression, subunit composition, and function of AMPA-type glutamate receptors are changed in activated microglia; possible contribution of GluA2 (GluR-B)-deficiency under pathological conditions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Genotype; Glutamic Acid; Hippocampus; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Microglia; Nerve Degeneration; Neurons; Protein Transport; Receptors, AMPA; Tumor Necrosis Factor-alpha | 2013 |
A preliminary experimental study on the cardiac toxicity of glutamate and the role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Arrhythmias, Cardiac; Calcium; Cell Survival; Cells, Cultured; DNA Fragmentation; Glutamic Acid; Male; Microscopy, Confocal; Myocardial Infarction; Rats; Rats, Wistar; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; Sodium Glutamate | 2013 |
Developmental regulation and activity-dependent maintenance of GABAergic presynaptic inhibition onto rod bipolar cell axonal terminals.
Topics: Action Potentials; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Carrier Proteins; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Mutation; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Receptors, GABA-A; Receptors, Glutamate; Receptors, Glycine; Retina; Retinal Bipolar Cells | 2013 |
Impaired motor learning attributed to altered AMPA receptor function in the cerebellum of rats with temporal lobe epilepsy: ameliorating effects of Withania somnifera and withanolide A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Carbamazepine; Cerebellum; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Transporter 1; Gene Expression Regulation; Glutamate Decarboxylase; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Learning Disabilities; Linear Models; Locomotion; Male; Motor Activity; Phytotherapy; Pilocarpine; Protein Binding; Psychomotor Performance; Rats; Rats, Wistar; Receptors, AMPA; RNA, Messenger; Time Factors; Tritium; Withania; Withanolides | 2013 |
Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cells, Cultured; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Glycine; HEK293 Cells; Humans; Protein Structure, Tertiary; Protein Subunits; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2013 |
A bionics chemical synapse.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Bionics; Computer Simulation; Electric Power Supplies; Electronics, Medical; Enzymes, Immobilized; Equipment Design; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Iontophoresis; Kinetics; Models, Theoretical; N-Methylaspartate; Synapses; Synaptic Transmission | 2013 |
Cornichons control ER export of AMPA receptors to regulate synaptic excitability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caenorhabditis elegans; Cells, Cultured; Endoplasmic Reticulum; Glutamic Acid; Membrane Proteins; Mutation; Neurons; Protein Transport; Receptors, AMPA; Synapses; Synaptic Transmission | 2013 |
Prelimbic cortex and ventral tegmental area modulate synaptic plasticity differentially in nucleus accumbens during cocaine-reinstated drug seeking.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cocaine-Related Disorders; Dendritic Spines; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; In Vitro Techniques; Male; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Synapses; Ventral Tegmental Area | 2014 |
Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Calcium; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Glycogen; Hydrogen-Ion Concentration; Hypoglycemia; Kynurenic Acid; Lactic Acid; Leukoencephalopathies; Mice; Mice, Inbred C57BL; Optic Nerve Injuries; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 2014 |
Computation of standard binding free energies of polar and charged ligands to the glutamate receptor GluA2.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acids; Binding Sites; Entropy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Quinoxalines; Receptors, Ionotropic Glutamate; Rotation; Static Electricity; Thermodynamics | 2014 |
Upregulation of glutamatergic transmission in anterior cingulate cortex in the diabetic rats with neuropathic pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diabetes Mellitus, Experimental; Excitatory Postsynaptic Potentials; Glutamic Acid; Gyrus Cinguli; Hot Temperature; Hyperalgesia; Male; Neuralgia; Neurons; Patch-Clamp Techniques; Physical Stimulation; Protein Kinase C; Rats, Sprague-Dawley; Receptors, Glutamate; Streptozocin; Synaptic Transmission; Touch; Up-Regulation | 2014 |
Increased response to glutamate in small diameter dorsal root ganglion neurons after sciatic nerve injury.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclohexylamines; Disease Models, Animal; Ganglia, Spinal; Glutamic Acid; Kainic Acid; Male; Neurons; Peripheral Nerve Injuries; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Sciatic Nerve | 2014 |
Astrocytes contribute to gamma oscillations and recognition memory.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Brain Waves; Calcium Signaling; Carbachol; Electroencephalography; Gene Expression; Glutamic Acid; Hippocampus; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Recognition, Psychology; Recombinant Proteins; Synaptic Transmission; Tetanus Toxin; Tissue Culture Techniques | 2014 |
Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biocatalysis; Calcium Channels; Cell Membrane; Disks Large Homolog 4 Protein; Female; Glutamic Acid; Guanylate Kinases; HEK293 Cells; Humans; Male; Membrane Proteins; Mice; Models, Biological; N-Methylaspartate; Protein Binding; Racemases and Epimerases; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2014 |
Prenatal nicotine is associated with reduced AMPA and NMDA receptor-mediated rises in calcium within the laterodorsal tegmentum: a pontine nucleus involved in addiction processes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Humans; Mice; Motivation; N-Methylaspartate; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance-Related Disorders; Tegmentum Mesencephali | 2015 |
Orexin-A differentially modulates AMPA-preferring responses of ganglion cells and amacrine cells in rat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Animals; Animals, Newborn; Calcium; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Guanosine Diphosphate; Male; Membrane Potentials; Orexin Receptor Antagonists; Orexins; Patch-Clamp Techniques; Rats; Retina; Retinal Ganglion Cells; Ryanodine; Signal Transduction; Thionucleotides | 2015 |
Glutamatergic transmission is involved in the long lasting sexual inhibition of sexually exhausted male rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Copulation; Dose-Response Relationship, Drug; Ejaculation; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Satiety Response; Sexual Behavior, Animal; Synaptic Transmission; Time Factors | 2015 |
Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enkephalins; Glutamic Acid; Immunohistochemistry; Inhalant Abuse; Long-Term Synaptic Depression; Morpholines; N-Methylaspartate; Neural Inhibition; Neurons; Nucleus Accumbens; Phenotype; Protein Precursors; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; RNA, Messenger; Solvents; Synaptic Transmission; Toluene | 2016 |
Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels, L-Type; Cations; Cell Membrane; Cells, Cultured; Glutamic Acid; Hippocampus; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Maze Learning; N-Methylaspartate; Neurons; Protein Kinase C; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate | 2015 |
Repeated administration of estradiol promotes mechanisms of sexual excitation and inhibition: Glutamate signaling in the ventromedial hypothalamus attenuates excitation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Appetitive Behavior; Cohort Studies; Copulation; Estradiol; Estrogens; Estrus; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hypothalamus; Male; Motor Activity; Ovariectomy; Rats; Rats, Long-Evans; Receptors, AMPA | 2015 |
Glutamate Stimulates Local Protein Synthesis in the Axons of Rat Cortical Neurons by Activating α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors and Metabotropic Glutamate Receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Brain-Derived Neurotrophic Factor; Calcium Channels; Calcium Signaling; Embryo, Mammalian; Gene Expression Regulation, Developmental; Glutamic Acid; Hippocampus; Kinetics; Primary Cell Culture; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Synapses; TOR Serine-Threonine Kinases; TRPV Cation Channels | 2015 |
Nitrous oxide directly inhibits action potential-dependent neurotransmission from single presynaptic boutons adhering to rat hippocampal CA3 neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CA3 Region, Hippocampal; Electric Stimulation; Female; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; N-Methylaspartate; Nitrous Oxide; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission | 2015 |
Roles of the NMDA Receptor and EAAC1 Transporter in the Modulation of Extracellular Glutamate by Low and High Affinity AMPA Receptors in the Cerebellum in Vivo: Differential Alteration in Chronic Hyperammonemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Extracellular Fluid; Glutamic Acid; Hyperammonemia; Male; Microdialysis; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors | 2015 |
Neuroprotective activity of stiripentol with a possible involvement of voltage-dependent calcium and sodium channels.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebral Cortex; Dioxolanes; Embryo, Mammalian; Fibrinolytic Agents; Glucose; Glutamic Acid; Hippocampus; Hirudins; Mice, Inbred C57BL; Neurofilament Proteins; Neuroglia; Neurons; Neuroprotective Agents; Protein Binding; Rats; Receptors, Glutamate; Recombinant Proteins; Sodium; Tritium | 2016 |
Postsynaptic Plasticity Triggered by Ca²⁺-Permeable AMPA Receptor Activation in Retinal Amacrine Cells.
Topics: Adamantane; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Animals; Calcium; Egtazic Acid; Excitatory Postsynaptic Potentials; Glutamic Acid; Goldfish; Membrane Potentials; Neuronal Plasticity; Receptors, AMPA; Retinal Bipolar Cells | 2016 |
Differential involvement of glutamatergic and catecholaminergic activity within the amygdala during taste aversion retrieval on memory expression and updating.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Avoidance Learning; Catecholamines; Cobalt; Conditioning, Psychological; Excitatory Amino Acid Agents; Exploratory Behavior; Glutamic Acid; Immobility Response, Tonic; Male; Mental Recall; Microdialysis; N-Methylaspartate; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Swimming; Taste | 2016 |
Nitric oxide modulates blood pressure through NMDA receptors in the rostral ventrolateral medulla of conscious rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arterial Pressure; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Heart Rate; Male; Medulla Oblongata; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred F344; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2016 |
AMPA/NMDA cooperativity and integration during a single synaptic event.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2016 |
GSG1L regulates the strength of AMPA receptor-mediated synaptic transmission but not AMPA receptor kinetics in hippocampal dentate granule neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Genetically Modified; Animals, Newborn; Biophysics; Claudins; Dentate Gyrus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; GABA Antagonists; Glutamic Acid; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Neurons; Organ Culture Techniques; Picrotoxin; Rats; Receptors, AMPA; Statistics, Nonparametric | 2017 |
Glial GLT-1 blockade in infralimbic cortex as a new strategy to evoke rapid antidepressant-like effects in rats.
Topics: Affect; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Citalopram; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Kainic Acid; Limbic Lobe; Male; Neuroglia; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Quinoxalines; Raphe Nuclei; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Veratridine | 2017 |
Gestational exposure to inorganic arsenic (iAs3+) alters glutamate disposition in the mouse hippocampus and ionotropic glutamate receptor expression leading to memory impairment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arsenic; Dentate Gyrus; Female; Glutamic Acid; Glutathione; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; Mice, Inbred Strains; Perforant Pathway; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Glutamate | 2018 |
Forebrain medial septum sustains experimental neuropathic pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Glutamic Acid; Male; Medulla Oblongata; Neuralgia; Nociception; Pain Measurement; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Septal Nuclei | 2018 |
Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Agents; Dopaminergic Neurons; Glutamic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Patch-Clamp Techniques; Receptors, Dopamine D1; Substance-Related Disorders; Synaptic Transmission; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 2 | 2018 |
Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Cues; Dendritic Spines; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; Mice; N-Methylaspartate; Neuronal Plasticity; Neurons; Nucleus Accumbens; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials; Synaptic Transmission | 2020 |
Glutamate Stimulation Dysregulates AMPA Receptors-Induced Signal Transduction Pathway in Leber's Inherited Optic Neuropathy Patient-Specific hiPSC-Derived Retinal Ganglion Cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Base Sequence; Cell Differentiation; Down-Regulation; Glutamic Acid; Humans; Induced Pluripotent Stem Cells; Optic Atrophy, Hereditary, Leber; Protein Binding; Receptors, AMPA; Retinal Ganglion Cells; Signal Transduction | 2019 |
Glioblastoma invasion and NMDA receptors: A novel prospect.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Line, Tumor; Cell Movement; Dizocilpine Maleate; Glioblastoma; Glutamic Acid; Humans; Neoplasm Invasiveness; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tumor Microenvironment; Up-Regulation | 2019 |
Endogenous glutamatergic inputs to the Parabrachial Nucleus/Kölliker-Fuse Complex determine respiratory rate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kolliker-Fuse Nucleus; Male; Microinjections; Parabrachial Nucleus; Quinoxalines; Rabbits; Respiratory Center; Respiratory Rate | 2020 |
AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis.
Topics: Adolescent; Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Inflammation; Kainic Acid; Male; Mice, Inbred C57BL; Osteoarthritis | 2020 |
Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Astrocytes; CA1 Region, Hippocampal; Circadian Clocks; Circadian Rhythm; Corticosterone; Darkness; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamic Acid; Memory; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Neuropil Threads; Open Field Test; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 2020 |
A human stem cell-derived test system for agents modifying neuronal N-methyl-D-aspartate-type glutamate receptor Ca
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Neurons; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2021 |
Conveyance of cortical pacing for parkinsonian tremor-like hyperkinetic behavior by subthalamic dysrhythmia.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; Glutamic Acid; Humans; Hyperkinesis; Male; Membrane Potentials; Mice, Inbred C57BL; Motor Cortex; Muscle, Skeletal; Optogenetics; Parkinson Disease, Secondary; Rats; Rats, Wistar; Subthalamic Nucleus; Synapses; Synaptic Transmission; Tremor | 2021 |
Supramammillary neurons projecting to the septum regulate dopamine and motivation for environmental interaction in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Consummatory Behavior; Dopamine; Dopaminergic Neurons; Female; Glutamic Acid; Hypothalamus, Posterior; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Neural Pathways; Optogenetics; Rats; Rats, Wistar; Reinforcement, Psychology; Septum of Brain; Ventral Tegmental Area | 2021 |
AMPA induced cognitive impairment in rats: Establishing the role of endoplasmic reticulum stress inhibitor, 4-PBA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Butylamines; Cognitive Dysfunction; Endoplasmic Reticulum Stress; Excitatory Amino Acid Agonists; Glutamic Acid; Locomotion; Male; Rats; Rats, Sprague-Dawley | 2021 |
Ceftriaxone Treatment Weakens Long-Term Synaptic Potentiation in the Hippocampus of Young Rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ceftriaxone; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2021 |
Differential expression of glutamatergic receptor subunits in the hippocampus in carioca high- and low-conditioned freezing rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anxiety; Glutamic Acid; Hippocampus; Rats; Receptors, N-Methyl-D-Aspartate; Spatial Memory | 2021 |
Excitotoxic damage to auditory nerve afferents and spiral ganglion neurons is correlated with developmental upregulation of AMPA and KA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamic Acid; Hair Cells, Auditory, Inner; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spiral Ganglion; Up-Regulation | 2021 |
Long-term exposure to high glucose induces changes in the expression of AMPA receptor subunits and glutamate transmission in primary cultured cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cell Death; Cells, Cultured; Cerebral Cortex; Female; Glucose; Glutamic Acid; N-Methylaspartate; Neurons; Protein Subunits; Rats, Wistar; Receptors, AMPA; Synaptophysin; Synaptotagmins; Vesicular Glutamate Transport Protein 1 | 2022 |
Optical analysis of glutamate spread in the neuropil.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Hippocampus; Neuropil; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2022 |
The many faces of the AMPA-type ionotropic glutamate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, Ionotropic Glutamate; Synapses | 2022 |
The action of Con-ikot-ikot toxin on single AMPA-type glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Ion Channels; Receptors, AMPA; Receptors, Glutamate | 2022 |
[Quantification of AMPA-type glutamate receptors trafficking by ligand-directed two-step labeling].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Fluorescent Dyes; Glutamic Acid; Ligands; Neurons; Receptors, AMPA | 2022 |
Affecting AMPA Receptor Biophysical Gating Properties with Negative Allosteric Modulators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; HEK293 Cells; Humans; Receptors, AMPA; Receptors, Glutamate | 2022 |
Layer-specific distribution and expression pattern of AMPA- and NMDA-type glutamate receptors in the barrel field of the adult rat somatosensory cortex: a quantitative electron microscopic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrons; Glutamic Acid; N-Methylaspartate; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synapses | 2023 |
Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Hyperthyroidism; Long-Term Potentiation; Mice; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2022 |
A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor.
Topics: 5' Untranslated Regions; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamic Acid; Receptors, AMPA; Receptors, Glutamate; Tretinoin | 2022 |
Targeting the kinetics mechanism of AMPA receptor inhibition by 2-oxo-3H-benzoxazole derivatives.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Benzoxazoles; Glutamic Acid; HEK293 Cells; Humans; Receptors, AMPA | 2022 |
Rutin prevents seizures in kainic acid-treated rats: evidence of glutamate levels, inflammation and neuronal loss modulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents; Carbamazepine; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Hippocampus; HMGB1 Protein; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Kainic Acid; N-Methylaspartate; Rats; Receptors, Interleukin-1; Rutin; Seizures; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Astaxanthin Protection against Neuronal Excitotoxicity via Glutamate Receptor Inhibition and Improvement of Mitochondrial Function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antioxidants; Calcium; Glutamic Acid; Humans; Mitochondria; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Reactive Oxygen Species; Receptors, AMPA; Receptors, Glutamate; Xanthophylls | 2022 |
α-Lipoic Acid Derivatives as Allosteric Modulators for Targeting AMPA-Type Glutamate Receptors' Gating Modules.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antioxidants; Glutamic Acid; HEK293 Cells; Humans; Receptors, AMPA; Thioctic Acid | 2022 |
Identification of rare missense mutations in the glutamate ionotropic receptor AMPA type subunit genes in schizophrenia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Exons; Glutamic Acid; Humans; Mutation, Missense; Schizophrenia | 2023 |
Translational patterns of ionotropic glutamate and GABA receptors during brain development and behavioral stimuli revealed by polysome profiling.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Glutamic Acid; Mice; Receptors, AMPA; Receptors, GABA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2023 |
Alternative Splicing of the Flip/Flop Cassette and TARP Auxiliary Subunits Engage in a Privileged Relationship That Fine-Tunes AMPA Receptor Gating.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Glutamic Acid; Mammals; Proteomics; Receptors, AMPA | 2023 |
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing.
Topics: Adenosine Deaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; Female; Glutamic Acid; Pregnancy; Rats; Receptors, AMPA; Risperidone; RNA; RNA Editing; Valproic Acid | 2023 |
[Glutamate and its ionotropic receptor agonists inhibit the response to acute hypoxia in carotid body of rats].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Dioxide; Carotid Body; Glutamic Acid; Hypoxia; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2023 |
Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cryoelectron Microscopy; Glutamic Acid; Synapses; Synaptic Transmission | 2023 |
Oxycodone withdrawal is associated with increased cocaine self-administration and aberrant accumbens glutamate plasticity in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Glutamic Acid; N-Methylaspartate; Nucleus Accumbens; Oxycodone; Rats; Rats, Sprague-Dawley; Self Administration | 2024 |
Effects of junk-food on food-motivated behavior and nucleus accumbens glutamate plasticity; insights into the mechanism of calcium-permeable AMPA receptor recruitment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Glutamic Acid; Male; Nucleus Accumbens; Obesity; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2024 |