alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with dizocilpine maleate in 180 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.56) | 18.7374 |
| 1990's | 106 (58.89) | 18.2507 |
| 2000's | 59 (32.78) | 29.6817 |
| 2010's | 14 (7.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Kemel, ML | 1 |
| Boddeke, HW; Massieu, L; Mengod, G; Palacios, JM; Rocamora, N | 1 |
| Garrone, B; Pittaluga, A; Raiteri, M | 1 |
| Donevan, SD; Jones, SM; Rogawski, MA | 1 |
| Carling, RW; Donald, AE; Foster, AC; Grimwood, S; Kemp, JA; Leeson, PD; Marshall, GR; Priestley, T; Smith, JD | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 1 |
| Dure, LS; Penney, JB; Young, AB | 2 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Parks, TN; Zhou, N | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 1 |
| Dodd, PR; Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Beattie, DT; Bruhn, T; Curtis, DR; Diemer, NH; Ebert, B; Ferkany, JW; Johansen, JS; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Ebert, B; Ferkany, JW; Holm, T; Johansen, TN; Jones, BE; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Anderson, MC; Chung, EY; Van Woert, MH | 1 |
| Balázs, R; Hack, N; Jørgensen, OS | 1 |
| Foster, AC; Gill, R; Woodruff, GN | 1 |
| Payne, RS; Rigor, BM; Schurr, A | 1 |
| Eller, RV; Greenamyre, JT; Porter, RH; Salim, M; Sandhu, FA; Zain, SB | 1 |
| Barnes, KA; Buchan, AM; Huang, ZG; Lesiuk, H; Li, H; Smith, KE; Xue, D | 1 |
| Bullock, S; Pearce, B; Potter, J; Rose, SP | 1 |
| Fedele, E; Raiteri, M; Versace, P | 1 |
| Anderton, BH; Leigh, PN; Meldrum, BS; Nunn, PB; Willis, CL | 1 |
| Klitgaard, H; Laudrup, P | 1 |
| Bregnedal, P; Brehm, L; Bøgesø, KP; Ebert, B; Frederiksen, K; Hansen, JJ; Krogsgaard-Larsen, P; Lenz, S | 1 |
| Akaike, A; Kimura, J; Shimohama, S; Tamura, Y; Yokota, T | 1 |
| Hamada, T; Ono, M; Shibata, S; Watanabe, A; Watanabe, S | 1 |
| Bruno, VM; Choi, DW; Dugan, LL; Giffard, RG; Goldberg, MP | 1 |
| Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Greenamyre, JT; Greene, JG | 2 |
| Oja, SS; Saransaari, P | 1 |
| Anderson, LA; Kelland, MD; Soltis, RP; Walters, JR | 1 |
| Carvalho, AP; Carvalho, CM; Duarte, CB; Ferreira, IL; Santos, PF | 1 |
| Devillers, JP; Simonnet, G | 1 |
| Gunne, LM; Johnson, AE; Lidén, A; Liminga, U; Lindefors, N; Wiesel, FA | 1 |
| Araki, N; Fukuuchi, Y; Komatsumoto, S; Ohta, K; Shibata, M; Shimazu, K | 1 |
| Beal, MF; Cipolloni, PB; Ferrante, RJ; Henshaw, DR; Jenkins, BG; Kowall, NW; Rosen, BR; Schulz, JB; Siwek, D | 1 |
| Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Acciarri, N; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Ferraro, L; Morari, M; Piazza, G | 1 |
| Couratier, P; Diop, AG; Hugon, J; Sindou, P; Spencer, PS; Tabaraud, F | 1 |
| Andou, Y; Enomoto, R; Kataoka, K; Mitani, A; Ogita, K; Yoneda, Y | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Nordholm, L; Sheardown, MJ; Suzdak, PD | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Buchan, AM; Li, H | 1 |
| Fagg, GE; Massieu, L; McVey, M; Thedinga, KH | 1 |
| De Bernardi, R; Ferro, F; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Baran, L; Bresink, I; Danysz, W; Hartmann, S; Kostowski, W; Krzascik, P; Parsons, CG; Przegalinski, E; Quack, G | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Jablońska, B; Kossut, M; Skangiel-Kramska, J | 1 |
| Borsini, F; Brambilla, A; Grippa, N; Prudentino, A | 1 |
| Barrios, M; Liljequist, S | 1 |
| Giffard, RG; Panter, SS; Regan, RF; Tilly, JL; Witz, A | 1 |
| Regan, RF | 1 |
| Cécyre, D; Le Jeune, H; Meaney, MJ; Quirion, R; Rowe, W | 1 |
| Cole, BJ; Stephens, DN | 1 |
| Fedele, E; Raiteri, M | 1 |
| Ben-Yoseph, O; Boxer, PA; Ross, BD | 1 |
| Ishihara, K; Sakai, N; Sasa, M; Tanaka, C; Ujihara, H | 1 |
| Albrecht, J; Borkowska, HD; Oja, SS; Saransaari, P | 1 |
| Bhardwaj, A; Hanley, DF; Ichord, RN; Koehler, RC; Northington, FJ; Traystman, RJ | 1 |
| Cebers, G; Hou, YN; Liljequist, S; Terenius, L | 1 |
| Argiolas, A; Iannucci, U; Melis, MR; Succu, S | 1 |
| Bristow, DR; Savidge, JR | 1 |
| Maeda, H; Minami, T; Ogita, K; Shuto, M; Yoneda, Y | 1 |
| Ayata, C; Ayata, G; Beal, MF; Christie, RH; Endres, M; Ferrante, RJ; Hara, H; Huang, PL; Hyman, BT; Kim, A; Matthews, RT; Moskowitz, MA; Waeber, C | 1 |
| Fontana, G; Gemignani, A; Marchese, S; Raiteri, M | 1 |
| Bourne, RC; Johnston, AN; Rogers, LJ; Rose, SP; Stewart, MG | 1 |
| Grover, LM | 1 |
| Asztely, F; Kokaia, M; Kullmann, DM; Min, MY | 1 |
| Horiuchi, K; Itoh, A; Itoh, T; Pleasure, D | 1 |
| Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G | 1 |
| Schwarzer, C; Sperk, G | 1 |
| Endo, T; Hara, S; Iwata, N; Kano, S; Kuriiwa, F; Mukai, T; Yanase, T | 1 |
| Black, IB; Crozier, RA; Levine, ES; Plummer, MR | 1 |
| Murali, SG; Sun, D | 1 |
| Allan, SM; Lawrence, CB; Rothwell, NJ | 1 |
| Capito, B; Martens, U; Wree, A | 1 |
| Johnson, AK; Xu, Z | 1 |
| Holmberg, L; Souverbie, F; Sundström, E | 1 |
| Carvalho, AP; Duarte, CB; Ferreira, IL | 1 |
| Behl, B; Hofmann, HP; Löscher, W; Potschka, H; Szabo, L; Treiber, HJ; Wlaź, P | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Yasuda, S | 1 |
| Beaver, CJ; Czepita, D; Daw, NW; Flavin, HJ; Fox, KD; Gordon, B; Ji, Q; Kirsch, JD; Reid, SN | 1 |
| Best, JD; Hastings, MH; McNulty, S; Schurov, IL; Sloper, PJ | 1 |
| Fryer, HJ; Kalb, RG; Knox, RJ; Strittmatter, SM | 1 |
| Gwag, BJ; Joe, E; Kim, EY; Kim, YH; Koh, JY; Sohn, S | 1 |
| Smith, AL; Thompson, ID | 1 |
| Goshima, Y; Kawashima, K; Misu, Y; Miyamae, T; Ohshima, E; Shibata, T; Shimizu, M; Suzuki, F | 1 |
| Bunney, BS; Shi, WX; Zhang, XX; Zheng, P | 1 |
| Bidmon, HJ; Mayer, B; Oermann, E; Palomero-Gallagher, N; Schleicher, A; Wu, J; Zilles, K | 1 |
| Kretschmer, BD | 1 |
| Chan, PH; Hirvonen, T; Keinänen, R; Koistinaho, J; Koponen, S; Närhi, M; Roivainen, R | 1 |
| Cornish, JL; Duffy, P; Kalivas, PW | 1 |
| Que, M; Schiene, K; Witte, OW; Zilles, K | 1 |
| Arcaya, JL; Cano, G; Cuesta, MC; Maixner, W; Sanchez, L; Suarez-Roca, H | 1 |
| Standley, CA | 1 |
| Dewar, KM; Elie, R; Vasiliadis, HM | 1 |
| Köhling, R; Qü, MS; Speckmann, EJ; Zilles, K | 1 |
| Calton, JL; Kang, MH; Moore, SD; Wilson, WA | 1 |
| Glazner, GW; Mattson, MP | 1 |
| Akaike, A; Honda, Y; Kashii, S; Sasa, M; Tamura, Y; Ujihara, H; Yasuyoshi, H; Zhang, S | 1 |
| Crusio, WE; Schwegler, H; Wu, J; Zilles, K | 1 |
| Balcar, VJ; FitzGibbon, T; Lawrance, ML; Pliss, L; Shave, E; Stastny, F | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Morinobu, S; Yasuda, S | 1 |
| Closier, M; Iop, F; Lestage, P; Lockhart, B | 1 |
| Aguilar, E; González, LC; Pinilla, L; Tena-Sempere, M | 2 |
| Ikonomidou, C; Stefovska, V; Turski, L | 1 |
| Dobbertin, A; Gervais, A; Glowinski, J; Mallat, M | 1 |
| Azmitia, EC; Hamada, S; Narita, M; Okado, N; Shibata, M; Shiga, T; Shutoh, F | 1 |
| Akaike, A; Honda, K; Inoue, R; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Cruise, L; Fuller, G; Ho, LK; Morris, BJ; Veitch, K | 1 |
| Alvarado, R; Camacho-Arroyo, I; Manjarrez, J | 1 |
| Coper, H; Lorenc-Koci, E; Ossowska, K; Pietraszek, M; Schulze, G; Smiałowska, M; Wardas, J; Wolfarth, S | 1 |
| Martens, U; Wree, A | 1 |
| Canonico, PL; Dianzani, C; Fantozzi, R; Lombardi, G; Miglio, G | 1 |
| Jensen, JB; Lund, TM; Pickering, DS; Schousboe, A; Timmermann, DB | 1 |
| Chvátal, A; Jendelová, P; Syková, E; Vargová, L | 1 |
| Kristensen, BW; Noraberg, J; Zimmer, J | 1 |
| Andrasfalvy, BK; Magee, JC | 1 |
| Gajkowska, B; Gordon-Krajcer, W | 1 |
| Dikranian, K; Farber, NB; Heinkel, C; Jiang, XP; Kim, SH | 1 |
| Augustin, I; Brose, N; Reim, K; Rhee, JS; Rosenmund, C; Sigler, A | 1 |
| Attwell, D; Hamann, M; Marie, H; Rossi, DJ | 1 |
| Cartier, L; Infante, C; Motles, E | 1 |
| Fahrner, A; Kiessling, M; Sommer, C | 1 |
| Duncan, G; Gu, H; Koller, B; Lieberman, J; Miyamoto, S; Snouwaert, J | 1 |
| Baudry, M; Panchenko, V; Shimono, K; Taketani, M | 1 |
| Chan, JY; Lo, WC; Tseng, CJ; Tung, CS | 1 |
| Beardsley, PM; Bespalov, AY; Willmore, CB | 1 |
| Kiessling, M; Kollmar, R; Schäbitz, WR; Schwab, S; Sommer, C | 1 |
| Bredy, TW; Cain, DP; Humpartzoomian, RA; Meaney, MJ | 1 |
| Díaz-Trelles, R; Fernández-Sánchez, MT; Novelli, A | 1 |
| Chang, LS; Chen, KK | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; Bortolozzi, A; Díaz-Mataix, L; Pons, S; Serrats, J | 1 |
| Duan, SM; Xu, AJ; Zeng, YM | 1 |
| De Mello, FG; Ferreira, ST; Louzada, PR; Mendonca-Silva, DL; Noël, F; Paula Lima, AC | 1 |
| Hamanaka, N; Ito, S; Matsumura, S; Minami, T; Nishizawa, M; Sasaguri, Y | 1 |
| Boksa, P; El-Khodor, BF; Flores, G; Srivastava, LK | 1 |
| Bennett, SA; Cheung, EC; Cregan, SP; Ferguson, KL; McIntosh, WC; Melanson-Drapeau, L; Park, DS; Slack, RS; Vanderluit, JL | 1 |
| Brennan, TJ; Pogatzki-Zahn, EM; Zahn, PK | 1 |
| Bai, D; Frandsen, A; Gong, XQ; Lu, WY; Pickering, DS; Wan, Y; Zabek, RL | 1 |
| de Groat, WC; Yoshiyama, M | 1 |
| Beneyto, M; Dean, B; Meador-Woodruff, JH; Scarr, E | 1 |
| Takemoto, Y | 1 |
| Huang, XF; Newell, KA; Zavitsanou, K | 1 |
| Zheng, S; Zuo, Z | 1 |
| Andrade, C; Mahy, N; Robledo, P; Rodríguez, MJ | 1 |
| An, TH; Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH | 1 |
| Butts, DA; Crair, MC; Janz, R; Kaeser, PS; Lu, HC; She, WC | 1 |
| Angelatou, F; Asprodini, E; Kouvaras, E; Pandis, C; Papatheodoropoulos, C; Sotiriou, E | 1 |
| Crowe, SL; Jorgensen, TJ; Kondratyev, A; Movsesyan, VA | 1 |
| Hasenöhrl, RU; Huston, JP; Palomero-Gallagher, N; Topic, B; Willuhn, I; Zilles, K | 1 |
| Diederich, K; Hanumanthiah, KM; Müller, HD; Schäbitz, WR; Schwab, S; Sommer, C | 1 |
| Fu, WM; Lin, TH; Tang, CH; Wu, MY; Yang, RS | 1 |
| Mahmoudian, M; Rahbar-Roshandel, N; Rahimi-Moghaddam, P; Tavakoli-Far, B | 1 |
| Adeola, M; Loo, M; Patil, T; Poles, A; Raffa, RB; Rawls, SM; Raymondi, N; Thomas, T | 1 |
| Boer, S; Dean, B; Ganfornina, MD; Reinieren, I; Sanchez, D; Scarr, E; Udawela, M; van den Boom, T | 1 |
| Bender, C; de Olmos, JS; de Olmos, S; Lorenzo, A; Rassetto, M | 1 |
| Balduzzi, M; Bellenchi, GC; Cammarota, R; Carnovale-Scalzo, G; De Nuccio, C; Di Stasi, AM; Frank, C; Leo, L; Malchiodi-Albedi, F; Mallozzi, C; Matteucci, A; Paradisi, S; Scorcia, G; Varano, M; Visentin, S | 1 |
| Addae, JI; Ali, N; Stone, TW | 1 |
| Nikitin, VP; Solntseva, SV | 1 |
| Bernardi, RE; Halbout, B; Hansson, AC; Spanagel, R | 1 |
| Carr, JA; Fu, Z; Go, A; Pamenter, ME; Powell, FL; Reid, SG | 1 |
| Fukushima, K; Imaizumi, Y; Ito, M; Kohmura, N; Sawada, K; Sugawara, M; Tabata, Y; Yamazaki, K | 1 |
| An, XL; Tai, FD | 1 |
| Akbarali, HI; Bowers, MS; Fitting, S; Hauser, KF; Knapp, PE; Marks, WD; Zou, S | 1 |
| Cabrera-Pastor, A; Felipo, V; Llansola, M; Taoro, L | 1 |
| Ramírez-Jarquín, UN; Tapia, R | 1 |
| Bailey, A; Bailey, CP; Georgiou, P; Heal, DJ; Wonnacott, S; Wright, VL | 1 |
| Goswami, K; Nandakumar, DN; Prasad, C; Ramaswamy, P; Srinivas, D | 1 |
1 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and dizocilpine maleate
| Article | Year |
|---|---|
Glutamatergic neurotransmission in hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Dizocilpine Maleate; Dogs; Glutamic Acid; Hepatic Encephalopathy; Humans; In Vitro Techniques; Rats; Receptors, Glutamate; Synaptic Transmission | 1993 |
179 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and dizocilpine maleate
| Article | Year |
|---|---|
Modulation of GABA release by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate and N-methyl-D-aspartate receptors in matrix-enriched areas of the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Histocytochemistry; Ibotenic Acid; Male; Nerve Endings; Perfusion; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptosomes; Tetrodotoxin; Veratridine | 1992 |
Administration of quinolinic acid in the rat hippocampus induces expression of c-fos and NGFI-A.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Gene Expression Regulation; Genes, fos; Hippocampus; Ibotenic Acid; In Situ Hybridization; Injections, Intraperitoneal; Male; Oligonucleotide Probes; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. II. Evidence for functional cooperation and for coexistence on the same axon terminal.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dizocilpine Maleate; Drug Interactions; Hippocampus; Ibotenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1992 |
Arcaine blocks N-methyl-D-aspartate receptor responses by an open channel mechanism: whole-cell and single-channel recording studies in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Cations, Divalent; Cells, Cultured; Dizocilpine Maleate; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1992 |
Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Cell Membrane; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Evoked Potentials; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Male; Neurons; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tritium | 1992 |
L-glutamate-evoked release of dopamine from synaptosomes of the rat striatum: involvement of AMPA and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical; Synaptosomes | 1992 |
Compartmentalization of excitatory amino acid receptors in human striatum.
Topics: Acetylcholinesterase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Caudate Nucleus; Corpus Striatum; Dizocilpine Maleate; Female; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Putamen; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
Excitatory amino acid binding sites in the caudate nucleus and frontal cortex of Huntington's disease.
Topics: Adolescent; Adult; Age Factors; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding, Competitive; Caudate Nucleus; Cell Death; Child; Dizocilpine Maleate; Frontal Lobe; Glycine; Humans; Huntington Disease; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Phencyclidine; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1991 |
Alterations in cortical [3H]kainate and alpha-[3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chronic Disease; Dizocilpine Maleate; Dogs; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Ibotenic Acid; Kainic Acid; Ligands; Tritium | 1991 |
Effects of morphine in the nucleus accumbens on stimulant-induced locomotion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Agents; Glutamine; Ibotenic Acid; Male; Morphine; Motor Activity; Neural Pathways; Nucleus Accumbens; Oligopeptides; Picrotoxin; Rats; Scopolamine; Synaptic Transmission | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotection.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Dizocilpine Maleate; Glycine; Ibotenic Acid; In Vitro Techniques; Indicators and Reagents; Isoxazoles; Male; Molecular Structure; Neurons; Propionates; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tritium | 1991 |
NMDA receptor agonists derived from ibotenic acid. Preparation, neuroexcitation and neurotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Callosum; Dizocilpine Maleate; Ibotenic Acid; In Vitro Techniques; Nervous System; Nervous System Diseases; Piperazines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical | 1990 |
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
The effects of inferior olive lesion on strychnine seizure.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Dizocilpine Maleate; Epilepsies, Myoclonic; Glutamates; Ibotenic Acid; Male; Olivary Nucleus; Pyridines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures; Strychnine; Tritium | 1990 |
Selective stimulation of excitatory amino acid receptor subtypes and the survival of cerebellar granule cells in culture: effect of kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Cerebellum; Dipeptides; Dizocilpine Maleate; DNA; Electric Stimulation; Glutamine; Ibotenic Acid; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Ibotenic Acid; Isoflurane; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Piperazines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1988 |
Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anti-Anxiety Agents; Benzodiazepines; Diltiazem; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; Neurons; Nifedipine; Pipecolic Acids; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1995 |
NMDA and AMPA receptors in transgenic mice expressing human beta-amyloid protein.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyloid beta-Peptides; Animals; Autoradiography; Base Sequence; Brain; Dizocilpine Maleate; DNA Primers; Gene Expression; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reference Values; RNA, Messenger; Tritium | 1993 |
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Infarction; Cerebrovascular Disorders; Dizocilpine Maleate; Drug Administration Schedule; Injections, Intraperitoneal; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reperfusion | 1993 |
Training chicks on a passive avoidance task modulates glutamate-stimulated inositol phosphate accumulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Avoidance Learning; Chickens; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Inositol Phosphates; Male; Neurotoxins; Prosencephalon; Receptors, Glutamate | 1993 |
Evaluation of the mechanisms underlying the kainate-induced impairment of [3H]dopamine release in the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electric Stimulation; Kainic Acid; Ketamine; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons, Afferent; Pipecolic Acids; Quinoxalines; Rats; Rats, Sprague-Dawley | 1993 |
Neuronal damage induced by beta-N-oxalylamino-L-alanine, in the rat hippocampus, can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Rats; Rats, Wistar | 1993 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Resolution, absolute stereochemistry, and pharmacology of the S-(+)- and R-(-)-isomers of the apparent partial AMPA receptor agonist (R,S)-2-amino-3-(3-hydroxy-5-phenylisoxazol-4-yl)propionic acid [(R,S)-APPA].
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Crystallography, X-Ray; Dizocilpine Maleate; Glycine; In Vitro Techniques; Isoxazoles; Kainic Acid; Rats; Receptors, AMPA; Stereoisomerism | 1994 |
Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; Nerve Degeneration; Neurons; Nicotine; Parasympathetic Nervous System; Parasympathomimetics; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
N-methyl-D-aspartate induces phase shifts in circadian rhythm of neuronal activity of rat SCN in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Circadian Rhythm; Dizocilpine Maleate; Electrophysiology; In Vitro Techniques; N-Methylaspartate; Neurons; Neuropeptide Y; Quinoxalines; Rats; Rats, Wistar; Suprachiasmatic Nucleus | 1994 |
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cytosol; Dizocilpine Maleate; Fetus; Glucose; Glutamic Acid; Glycine; Hypothermia, Induced; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurons | 1994 |
Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands.
Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glycine; Hydrogen Bonding; Isoxazoles; Ligands; Molecular Conformation; Molecular Structure; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship; Thermodynamics | 1994 |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain Diseases; Cell Death; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Isoquinolines; Male; Malonates; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Succinate Dehydrogenase | 1995 |
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles | 1994 |
A role for non-NMDA excitatory amino acid receptors in regulating the basal activity of rat globus pallidus neurons and their activation by the subthalamic nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Extracellular Space; GABA-A Receptor Antagonists; Globus Pallidus; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Thalamic Nuclei | 1994 |
Release of [3H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca2+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Nicotinic Acids; Nipecotic Acids; Oximes; Quisqualic Acid; Retina; Tritium | 1994 |
Modulation of neuropeptide FF release from rat spinal cord slices by glutamate. Involvement of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Membranes; N-Methylaspartate; Neuropeptides; Neurotoxins; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Autoradiography; Basal Ganglia; Basal Ganglia Diseases; Brain; Dizocilpine Maleate; Excitatory Amino Acids; Female; Fluphenazine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Situ Hybridization; Muscimol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stereotyped Behavior; Synaptic Transmission | 1994 |
Presynaptic ionotropic glutamate receptors modulate in vivo release and metabolism of striatal dopamine, noradrenaline, and 5-hydroxytryptamine: involvement of both NMDA and AMPA/kainate subtypes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serotonin | 1994 |
Involvement of free radicals in excitotoxicity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Death; Cells, Cultured; Cyclic N-Oxides; Dizocilpine Maleate; Electrophysiology; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Kainic Acid; Male; N-Methylaspartate; Neurons; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1995 |
Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Brain Diseases; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Male; Malonates; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase | 1995 |
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcimycin; Cerebral Cortex; Child; Cycloleucine; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Male; Middle Aged; N-Methylaspartate; Phosphatidylinositols; Quisqualic Acid; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrodotoxin | 1995 |
Modulation of tau neuronal expression induced by NMDA, non-NMDA and metabotropic glutamate receptor agonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcimycin; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Immunoenzyme Techniques; Microscopy, Confocal; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; tau Proteins | 1995 |
Binding of [3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and [3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cell Membrane; Dizocilpine Maleate; Female; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Receptors, Glutamate; Spermidine; Thiocyanates; Tissue Distribution | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gerbillinae; Hippocampus; Ibotenic Acid; Ischemic Attack, Transient; Kinetics; Male; Neurons; Piperidines; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Diseases; Dizocilpine Maleate; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Prosencephalon; Quinoxalines; Rats; Rats, Wistar | 1993 |
A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biomarkers; Cell Death; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Drug Administration Schedule; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections; Injections, Intraperitoneal; Kainic Acid; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neurotoxins; Pipecolic Acids; Piperazines; Quinolinic Acid; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Cycloleucine; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Somatostatin; Tetrodotoxin | 1996 |
Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amantadine; Animals; Anticonvulsants; Binding, Competitive; Cells, Cultured; Dizocilpine Maleate; In Vitro Techniques; Kinetics; Male; Mice; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Transient increase of AMPA and NMDA receptor binding in the barrel cortex of mice after tactile stimulation.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arousal; Brain Mapping; Dizocilpine Maleate; Dominance, Cerebral; Mice; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Somatosensory Cortex; Synaptic Transmission; Touch; Up-Regulation; Vibrissae | 1996 |
Pharmacological characterization of AMPA-induced biting behaviour in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nociceptors; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Developmental changes in glutamate receptor-activated translocation of protein kinase C in cerebellar granule neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Carcinogens; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tritium | 1996 |
Ultrastructure of excitotoxic neuronal death in murine cortical culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aurintricarboxylic Acid; Bisbenzimidazole; Cell Death; Cells, Cultured; Cerebral Cortex; Cycloheximide; Dactinomycin; Dizocilpine Maleate; DNA Damage; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Mice; Microscopy, Electron; Mitochondria; Neuroglia; Neurons; Neurotoxins; Propidium; Protein Synthesis Inhibitors; Vacuoles | 1995 |
The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Cobalt; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Spinal Cord; Staining and Labeling; Time Factors | 1996 |
Ionotropic glutamate receptor subtypes in the aged memory-impaired and unimpaired Long-Evans rat.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Brain; Dizocilpine Maleate; Male; Memory; Rats; Receptors, Glutamate | 1996 |
AMPA antagonists differ from NMDA antagonists in their effects on operant DRL and delayed matching to position tasks.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Conditioning, Operant; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Reinforcement, Psychology | 1996 |
Desensitization of AMPA receptors and AMPA-NMDA receptor interaction: an in vivo cyclic GMP microdialysis study in rat cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Noninvasive assessment of the relative roles of cerebral antioxidant enzymes by quantitation of pentose phosphate pathway activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbon Isotopes; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Deferoxamine; Deuterium; Dizocilpine Maleate; Fetus; Gas Chromatography-Mass Spectrometry; Glucose; Hydrogen Peroxide; Iron; Kainic Acid; Kinetics; N-Methylaspartate; Neuroglia; Neurons; Pentose Phosphate Pathway; Putamen; Quinoxalines; Rats | 1996 |
Electrophysiological and pharmacological characteristics of ionotropic glutamate receptors in medial vestibular nucleus neurons: a whole cell patch clamp study in acutely dissociated neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Membrane Potentials; Microscopy, Polarization; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glutamate; Vestibular Nuclei | 1996 |
Release of [3H]dopamine from striatal and cerebral cortical slices from rats with thioacetamide-induced hepatic encephalopathy: different responses to stimulation by potassium ions and agonists of ionotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Hepatic Encephalopathy; Kainic Acid; Male; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Thioacetamide; Tritium | 1997 |
Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrulline; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription Factor AP-1 | 1997 |
N-methyl-D-aspartic acid-induced penile erection and yawning: role of hypothalamic paraventricular nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hemoglobins; Male; Methylene Blue; Microdialysis; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Yawning | 1997 |
Distribution of Ca(2+)-permeable AMPA receptors among cultured rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cells, Cultured; Cerebellum; Culture Media; Culture Media, Serum-Free; Diuretics; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Manganese; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1997 |
Inhibition of [3H]MK-801 binding by ferrous (II) but not ferric (III) ions in a manner different from that by sodium nitroprusside (II) in rat brain synaptic membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chlorides; Dizocilpine Maleate; Ferric Compounds; Ferricyanides; Ferrocyanides; Ferrous Compounds; Ion Channels; Iron Chelating Agents; Kainic Acid; Male; Nitroprusside; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1997 |
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Binding Sites; Corpus Striatum; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1997 |
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Exposure to light prior to hatching induces asymmetry of receptor binding in specific regions of the chick forebrain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Chick Embryo; Dizocilpine Maleate; Eye; Functional Laterality; Light; Muscimol; Prosencephalon; Receptors, GABA; Receptors, Glutamate; Tritium | 1997 |
Evidence for postsynaptic induction and expression of NMDA receptor independent LTP.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Axons; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Male; Membrane Potentials; Models, Neurological; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Long-term potentiation and dual-component quantal signaling in the dentate gyrus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dentate Gyrus; Dizocilpine Maleate; Evoked Potentials; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Long-Term Potentiation; Perforant Pathway; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses | 1998 |
AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Channel Blockers; Cell Death; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Homeostasis; Humans; Kainic Acid; Membrane Potentials; Neurons; Neurotoxins; Nimodipine; Potassium; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Spider Venoms | 1998 |
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium | 1998 |
Glutamate-stimulated neuropeptide Y mRNA expression in the rat dentate gyrus: a prominent role of metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Injections; Injections, Intraperitoneal; Male; N-Methylaspartate; Neuropeptide Y; Neuropeptides; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger | 1998 |
Characterization of temperature rise of the brain and the rectum following intracerebroventricular administration of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Non-Narcotic; Animals; Body Temperature; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indomethacin; Injections, Intraventricular; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Rectum | 1998 |
Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Hippocampus; N-Methylaspartate; Nerve Growth Factors; Neurotrophin 3; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Stimulation of Na+-K+-2Cl- cotransporter in neuronal cells by excitatory neurotransmitter glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Bumetanide; Carrier Proteins; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agents; Gene Expression Regulation; Glutamic Acid; Humans; Kinetics; N-Methylaspartate; Neuroblastoma; Neurons; Potassium; Receptors, Glutamate; Sodium-Potassium-Chloride Symporters; Tumor Cells, Cultured | 1998 |
Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Interleukin-1; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Interleukin-1; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins | 1998 |
Septotemporal distribution of [3H]MK-801, [3H]AMPA and [3H]Kainate binding sites in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Image Processing, Computer-Assisted; Kainic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
Non-NMDA receptor antagonist-induced drinking in rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Cerebral Ventricles; Dizocilpine Maleate; Drinking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Losartan; Male; Quinoxalines; Rats; Rats, Sprague-Dawley | 1998 |
NMDA and AMPA receptors evoke transmitter release from noradrenergic axon terminals in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1998 |
Kainate-induced retina amacrine-like cell damage is mediated by AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium Radioisotopes; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Neuromuscular Depolarizing Agents; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1998 |
LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Quinolones; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium | 1998 |
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Brain Stem; Dizocilpine Maleate; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Inferior Colliculi; N-Methylaspartate; Neuroprotective Agents; Propylthiouracil; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Injection of MK-801 affects ocular dominance shifts more than visual activity.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye; Functional Laterality; N-Methylaspartate; Neuronal Plasticity; Sensory Deprivation; Vision, Monocular; Vision, Ocular; Visual Cortex | 1999 |
Glutamatergic induction of CREB phosphorylation and Fos expression in primary cultures of the suprachiasmatic hypothalamus in vitro is mediated by co-ordinate activity of NMDA and non-NMDA receptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cricetinae; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Gene Expression; Genes, fos; Glutamic Acid; Kainic Acid; Male; Mesocricetus; N-Methylaspartate; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Suprachiasmatic Nucleus | 1999 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Culture Techniques; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Chromans; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Dopamine Agonists; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Free Radicals; Hypoglycemic Agents; Insulin; Kainic Acid; Lipid Peroxidation; Mice; Microscopy, Electron; Mitochondrial Swelling; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Oligopeptides; Oxidative Stress; Pregnancy; Zinc | 1999 |
Spatiotemporal patterning of glutamate receptors in developing ferret striate cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ferrets; Kainic Acid; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium; Visual Cortex | 1999 |
Some interactions of L-DOPA and its related compounds with glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Kainic Acid; Levodopa; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Xenopus laevis | 1999 |
Opposite modulation of cortical N-methyl-D-aspartate receptor-mediated responses by low and high concentrations of dopamine.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Membrane Potentials; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Different nitric oxide synthase inhibitors cause rapid and differential alterations in the ligand-binding capacity of transmitter receptors in the rat cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Cerebral Cortex; Dizocilpine Maleate; Kainic Acid; Male; Muscimol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Oxotremorine; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium | 1999 |
Modulation of the mesolimbic dopamine system by glutamate: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Binding, Competitive; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Homovanillic Acid; Limbic System; Male; Microdialysis; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 1999 |
Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical layers: regulation by N-methyl-D-aspartate receptors and glucocorticoids.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cortical Spreading Depression; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Disease Susceptibility; Dizocilpine Maleate; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Indomethacin; Isoenzymes; Male; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Parietal Lobe; Phospholipases A; Phospholipases A2; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Quinacrine; Quinoxalines; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transcriptional Activation | 1999 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Widespread up-regulation of N-methyl-D-aspartate receptors after focal photothrombotic lesion in rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Intracranial Thrombosis; Kainic Acid; Light; Male; Radiation Injuries, Experimental; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Time Factors; Up-Regulation | 1999 |
Opposite modulation of capsaicin-evoked substance P release by glutamate receptors.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Nociceptors; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Interaction between dopamine and glutamate receptors following treatment with NMDA receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Ionotropic glutamate and GABA receptors in human epileptic neocortical tissue: quantitative in vitro receptor autoradiography.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Binding Sites; Dizocilpine Maleate; Epilepsy; Female; Humans; Kainic Acid; Male; Muscimol; Neocortex; Receptors, AMPA; Receptors, GABA-A; Receptors, Glutamate; Tissue Distribution | 1999 |
NMDA-Receptor-dependent synaptic activation of voltage-dependent calcium channels in basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Bicuculline; Calcium; Calcium Channels; Cesium; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; N-Methylaspartate; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin | 2000 |
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain-Derived Neurotrophic Factor; Calcium; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Embryo, Mammalian; Glutamic Acid; Homeostasis; Kinetics; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha | 2000 |
Involvement of NMDA-receptor in kainate-induced neurotoxicity in cultured fetal retinal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Retina | 2000 |
Water maze and radial maze learning and the density of binding sites of glutamate, GABA, and serotonin receptors in the hippocampus of inbred mouse strains.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Autoradiography; Dentate Gyrus; Dizocilpine Maleate; Escape Reaction; Hippocampus; Kainic Acid; Learning; Male; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, Serotonin; Serotonin; Species Specificity; Tritium | 2000 |
Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Brain Chemistry; Carboxypeptidases; Cold Temperature; Cycloleucine; Cyclopropanes; Dipeptides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Kainic Acid; Male; Nerve Tissue Proteins; Phosphoserine; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tetrazoles | 2001 |
Characterization of audiogenic-like seizures in naive rats evoked by activation of AMPA and NMDA receptors in the inferior colliculus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Suckling; Benzothiadiazines; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Hypothyroidism; Inferior Colliculi; Injections, Intraventricular; Male; Maternal Exposure; N-Methylaspartate; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 2000 |
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium | 2000 |
Regulation of prolactin secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in male rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Depression, Chemical; Dizocilpine Maleate; Male; Pituitary Gland; Prolactin; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sexual Maturation | 2000 |
Neuronal death enhanced by N-methyl-D-aspartate antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Injuries; Cell Death; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Memantine; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Piperazines; Propionates; Quinoxalines; Rats; Rats, Wistar; Wounds and Injuries | 2000 |
Activation of ionotropic glutamate receptors reduces the production of transforming growth factor-beta2 by developing neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta | 2000 |
Long term depletion of serotonin leads to selective changes in glutamate receptor subunits.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Dizocilpine Maleate; Fenclonine; Glutamic Acid; Male; Neuronal Plasticity; Neurons; Norepinephrine; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serotonin; Synaptic Transmission; Time Factors; Tritium | 2000 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and PI3 kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Corpus Striatum; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Wortmannin | 2001 |
Differential effects of NMDA antagonists microinjections into the nucleus reticularis pontis caudalis on seizures induced by pentylenetetrazol in the rat.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Microinjections; N-Methylaspartate; Pentylenetetrazole; Pons; Rats; Rats, Wistar; Reticular Formation; Seizures | 2001 |
Decline in motor functions in aging is related to the loss of NMDA receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle Joint; Biomarkers; Biomechanical Phenomena; Brain Mapping; Cell Count; Dizocilpine Maleate; Dopamine; Electromyography; Female; Glutamic Acid; Learning Disabilities; Maze Learning; Movement Disorders; Muscle, Skeletal; Nerve Tissue Proteins; Pliability; Psychomotor Performance; Raclopride; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Tyrosine 3-Monooxygenase | 2001 |
Distribution of [3H]MK-801, [3H]AMPA and [3H]Kainate binding sites in rat hippocampal long-term slice cultures isolated from external afferents.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Dizocilpine Maleate; Hippocampus; Kainic Acid; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Glutamate; Thymidine; Tissue Distribution | 2001 |
Characterization of ionotropic glutamate receptors in human lymphocytes.
Topics: 2-Amino-5-phosphonovalerate; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies, Monoclonal; Calcium; CD3 Complex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Kainic Acid; Lymphocytes; N-Methylaspartate; Phytohemagglutinins; Quinoxalines; Receptors, Glutamate | 2001 |
Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Benzothiadiazines; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flunarizine; Gene Expression Regulation, Developmental; Ion Channel Gating; Lanthanum; Macromolecular Substances; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nifedipine; omega-Conotoxins; Polyamines; Protein Subunits; Receptors, AMPA; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Spermine; Tetrodotoxin | 2001 |
Glutamate, NMDA, and AMPA induced changes in extracellular space volume and tortuosity in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Chelating Agents; Diffusion; Dizocilpine Maleate; Edema; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Gliosis; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Spinal Cord | 2001 |
Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Isoxazoles; Kainic Acid; Microtubule-Associated Proteins; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Nissl Bodies; Nuclear Proteins; Propidium; Propionates; Quinoxalines; Rats; Rats, Wistar | 2001 |
Distance-dependent increase in AMPA receptor number in the dendrites of adult hippocampal CA1 pyramidal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Dendrites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Microinjections; N-Methylaspartate; Neural Pathways; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 2001 |
Excitotoxicity-induced expression of amyloid precursor protein (beta-APP) in the hippocampus and cortex of rat brain. an electron-microscopy and biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Dizocilpine Maleate; Hippocampus; Immunohistochemistry; Male; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques | 2001 |
Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity.
Topics: Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Carbazoles; Cerebral Cortex; Clonidine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Models, Neurological; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Phenazocine; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Scopolamine | 2002 |
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Protein Isoforms; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines; Type C Phospholipases | 2002 |
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Induction and blockade of epileptic foci by intracerebral injection of glutamatergic agonists and antagonists in frerly moving cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cats; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Seizures | 2002 |
[3H]muscimol binding to gamma-aminobutyric acid(A) receptors is upregulated in CA1 neurons of the gerbil hippocampus in the ischemia-tolerant state.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Ischemia; Cell Count; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Hippocampus; Immunohistochemistry; Ischemic Preconditioning; Ligands; Male; Muscimol; Neurons; Receptors, GABA-A; Tritium; Up-Regulation | 2002 |
Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Deoxyglucose; Dizocilpine Maleate; DNA; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Mice; Mice, Knockout; Motor Activity; Phenotype; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2002 |
Chronic multichannel recordings from organotypic hippocampal slice cultures: protection from excitotoxic effects of NMDA by non-competitive NMDA antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Dizocilpine Maleate; Electrodes, Implanted; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Memantine; N-Methylaspartate; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2002 |
Carbon monoxide and metabotropic glutamate receptors in rat nucleus tractus solitarii: participation in cardiovascular effect.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Carbon Monoxide; Cardiovascular System; Cycloleucine; Deuteroporphyrins; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Heme Oxygenase (Decyclizing); Hemin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Solitary Nucleus | 2002 |
Site-selective N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonists produce distinct effects in rats performing complex discriminations.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Memory; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Exogenous brain-derived neurotrophic factor prevents postischemic downregulation of [3H]muscimol binding to GABA(A) receptors in the cortical penumbra.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cerebral Infarction; Dizocilpine Maleate; Down-Regulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; Male; Muscimol; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tritium | 2003 |
Partial reversal of the effect of maternal care on cognitive function through environmental enrichment.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Cognition; Discrimination Learning; Dizocilpine Maleate; Electrophysiology; Environment; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Maternal Behavior; Maze Learning; Membrane Potentials; Psychomotor Performance; Rats; Rats, Long-Evans; Reaction Time; Receptors, Glutamate | 2003 |
RNA synthesis-dependent potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated toxicity by antihistamine terfenadine in cultured rat cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Aniline Compounds; Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Dactinomycin; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Histamine; Histamine H1 Antagonists; Kainic Acid; Neurons; Protein Synthesis Inhibitors; Rats; Receptors, AMPA; RNA; Terfenadine; Xanthenes | 2003 |
Effect of excitatory amino acid receptor agonists on penile erection after administration into paraventricular nucleus of hypothalamus in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley | 2003 |
In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT(2A) receptors: effect of antipsychotic drugs.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminopyridines; Anesthetics, Local; Animals; Antipsychotic Agents; Benzopyrans; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Immunohistochemistry; In Situ Hybridization; Indoles; Indophenol; Male; Mice; Mice, Inbred C57BL; Microdialysis; Piperidines; Prazosin; Prefrontal Cortex; Quinoxalines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Thiazoles; Time Factors | 2003 |
Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Dizocilpine Maleate; Female; Injections, Spinal; Male; Mice; N-Methylaspartate; Nociceptors; Pain Threshold; Propofol; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Cellular Senescence; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Eye Proteins; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Picrotoxin; Receptors, AMPA; Receptors, GABA; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Taurine | 2004 |
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basidiomycota; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Heterocyclic Compounds; Indoles; Injections, Spinal; Japan; Kainic Acid; Lumbosacral Region; Male; Mice; Mice, Inbred Strains; Mushroom Poisoning; Oximes; Pain; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Time Factors | 2004 |
Effects of birth insult and stress at adulthood on excitatory amino acid receptors in adult rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Birth Injuries; Brain; Cesarean Section; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hypoxia; Iodine Isotopes; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stress, Physiological; Tritium | 2004 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incisional pain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Neuronal Plasticity; Pain, Postoperative; Physical Stimulation; Posterior Horn Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2005 |
D-aspartate and NMDA, but not L-aspartate, block AMPA receptors in rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; D-Aspartic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Kainic Acid; Membrane Potentials; Microinjections; N-Methylaspartate; Neurons; Oocytes; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Complementary; Stereoisomerism; Xenopus laevis | 2005 |
Supraspinal and spinal alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid and N-methyl-D-aspartate glutamatergic control of the micturition reflex in the urethane-anesthetized rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Anesthetics, Intravenous; Animals; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electromyography; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Injections, Intraventricular; Injections, Spinal; Isoquinolines; N-Methylaspartate; Neural Pathways; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrazoles; Urethane; Urinary Bladder; Urination | 2005 |
Cortical glutamatergic markers in schizophrenia.
Topics: 2-Amino-5-phosphonovalerate; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Biomarkers; Case-Control Studies; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; In Situ Hybridization; Kainic Acid; Male; Middle Aged; Postmortem Changes; Radioligand Assay; Receptors, Glutamate; Schizophrenia; Tritium | 2005 |
Depressor responses to L-proline microinjected into the rat ventrolateral medulla are mediated by ionotropic excitatory amino acid receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Proline; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2005 |
Ionotropic glutamate receptor binding in the posterior cingulate cortex in schizophrenia patients.
Topics: Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Autoradiography; Case-Control Studies; Demography; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Humans; Kainic Acid; Male; Middle Aged; Postmortem Changes; Protein Binding; Receptors, Glutamate; Schizophrenia; Tritium | 2005 |
Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cell Survival; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Pertussis Toxin; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability.
Topics: Adaptation, Physiological; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Denervation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Muscarinic Antagonists; Muscimol; Neural Inhibition; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Septal Nuclei; Synaptic Transmission; Taurine; Tritium | 2005 |
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley | 2005 |
Role of efficient neurotransmitter release in barrel map development.
Topics: Adenylyl Cyclases; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Blotting, Western; Brain Mapping; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; GTP-Binding Proteins; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Models, Neurological; N-Methylaspartate; Neural Pathways; Neuronal Plasticity; Neurotransmitter Agents; Patch-Clamp Techniques; Somatosensory Cortex; Synapsins; Thalamus; Time Factors | 2006 |
Differential expression of NMDA and AMPA receptor subunits in rat dorsal and ventral hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Autoradiography; Blotting, Western; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression; Hippocampus; In Situ Hybridization; In Vitro Techniques; Male; Protein Binding; Protein Subunits; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium | 2006 |
Rapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activation.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Survival; Cerebral Cortex; Dizocilpine Maleate; DNA Repair Enzymes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Fluorescent Antibody Technique; Gamma Rays; Gene Expression; Histones; Hydrogen Peroxide; MRE11 Homologue Protein; N-Methylaspartate; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2006 |
Impaired maze performance in aged rats is accompanied by increased density of NMDA, 5-HT1A, and alpha-adrenoceptor binding in hippocampus.
Topics: Adrenergic Agents; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Protein Binding; Radioligand Assay; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha; Receptors, N-Methyl-D-Aspartate; Serotonin Agents; Statistics, Nonparametric; Tritium | 2007 |
Brain-derived neurotrophic factor but not forced arm use improves long-term outcome after photothrombotic stroke and transiently upregulates binding densities of excitatory glutamate receptors in the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Brain-Derived Neurotrophic Factor; Cerebral Infarction; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Forelimb; GABA Agonists; Intracranial Thrombosis; Ligands; Male; Motor Activity; Muscimol; Physical Therapy Modalities; Rats; Rats, Wistar; Receptors, Glutamate; Restraint, Physical; Stroke; Up-Regulation | 2008 |
Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Male; N-Methylaspartate; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Phosphorylation; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tibia; Time Factors | 2008 |
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formazans; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Quinoxalines; Receptors, Kainic Acid; Reperfusion Injury; Tetrazolium Salts; Time Factors | 2009 |
Topiramate antagonizes NMDA- and AMPA-induced seizure-like activity in planarians.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; N-Methylaspartate; Neuroprotective Agents; Planarians; Quinoxalines; Seizures; Topiramate | 2009 |
Decreased kainate receptors in the hippocampus of apolipoprotein D knockout mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apolipoproteins D; Autoradiography; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Hippocampus; Ketanserin; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Antagonists; Pirenzepine; Protein Binding; Radioligand Assay; Radionuclide Imaging; Receptors, Kainic Acid; Tissue Distribution; Tritium | 2010 |
Involvement of AMPA/kainate-excitotoxicity in MK801-induced neuronal death in the retrosplenial cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cell Death; Cerebral Cortex; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Limbic System; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2010 |
Curcumin protects against NMDA-induced toxicity: a possible role for NR2A subunit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Calcium; Cells, Cultured; Curcumin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Time Factors | 2011 |
Effects of AMPA and clomethiazole on spreading depression cycles in the rat neocortex in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chlormethiazole; Cortical Spreading Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; GABA Modulators; Male; Neocortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2011 |
Peculiarities of amnesia development during memory reconsolidation impairment induced by isolated or combined treatment with neurotransmitter receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Conditioning, Psychological; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Helix, Snails; Memory; Models, Animal; N-Methylaspartate; Receptors, Neurotransmitter; Serotonin Antagonists | 2013 |
Incubation of cocaine seeking following brief cocaine experience in mice is enhanced by mGluR1 blockade.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Conditioning, Operant; Cues; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Food; Heterocyclic Compounds, 3-Ring; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Protein Binding; Receptors, Metabotropic Glutamate; Self Administration; Time Factors; Tritium | 2014 |
Glutamate receptors in the nucleus tractus solitarius contribute to ventilatory acclimatization to hypoxia in rat.
Topics: Acclimatization; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chemoreceptor Cells; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia; Male; N-Methylaspartate; Pulmonary Ventilation; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus | 2014 |
Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cell Differentiation; Cell Line; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophysiology; Gene Expression Regulation; Hippocampus; Humans; Kainic Acid; N-Methylaspartate; Neural Stem Cells; Quinoxalines; Receptors, Ionotropic Glutamate | 2014 |
AVP and Glu systems interact to regulate levels of anxiety in BALB/cJ mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anxiety; Arginine Vasopressin; Dizocilpine Maleate; Glutamine; Indoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pyrrolidines; Quinoxalines | 2014 |
Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; AIDS-Associated Nephropathy; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corpus Striatum; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Morphine; N-Methylaspartate; Primary Cell Culture; Receptors, Opioid, mu; Ryanodine; Sodium; Synapses; tat Gene Products, Human Immunodeficiency Virus | 2014 |
Roles of the NMDA Receptor and EAAC1 Transporter in the Modulation of Extracellular Glutamate by Low and High Affinity AMPA Receptors in the Cerebellum in Vivo: Differential Alteration in Chronic Hyperammonemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Extracellular Fluid; Glutamic Acid; Hyperammonemia; Male; Microdialysis; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors | 2015 |
Chronic GABAergic blockade in the spinal cord in vivo induces motor alterations and neurodegeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Bicuculline; Dizocilpine Maleate; Drug Interactions; GABA Antagonists; Gait; Male; Motor Activity; Motor Neurons; Muscle Hypotonia; Nerve Degeneration; Rats; Receptors, Glycine; Spinal Cord; Strychnine | 2017 |
Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding.
Topics: Aconitine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha7 Nicotinic Acetylcholine Receptor; Analgesics, Opioid; Animals; Conditioning, Classical; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Hippocampus; Mice; Morphine; Nicotinic Antagonists; Opioid-Related Disorders; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recurrence; Tritium | 2019 |
Glioblastoma invasion and NMDA receptors: A novel prospect.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Line, Tumor; Cell Movement; Dizocilpine Maleate; Glioblastoma; Glutamic Acid; Humans; Neoplasm Invasiveness; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tumor Microenvironment; Up-Regulation | 2019 |