alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with cyclothiazide in 93 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 48 (51.61) | 18.2507 |
| 2000's | 40 (43.01) | 29.6817 |
| 2010's | 4 (4.30) | 24.3611 |
| 2020's | 1 (1.08) | 2.80 |
| Authors | Studies |
|---|---|
| Butini, S; Campiani, G; Christensen, JK; Coccone, SS; De Angelis, M; Fiorini, I; Gemma, S; Guarino, E; Morelli, E; Novellino, E; Pickering, DS; Schousboe, A; Trotta, F | 1 |
| England, PM; Fleming, JJ | 1 |
| Ambros-Ingerson, J; Hall, RA; Kessler, M; Lynch, G; Quan, A | 1 |
| Gallo, V; Mayer, ML; Patneau, DK; Winters, C; Wright, PW | 1 |
| Burnett, JP; May, PC; Mayne, NG; Sharp, RL; Snyder, YM | 1 |
| Burnett, JP; Desai, MA; Schoepp, DD | 1 |
| Burnett, JP; Desai, MA; Ornstein, PL; Schoepp, DD | 1 |
| Barnes, JM; Dev, KK; Henley, JM | 1 |
| Blanchard, JC; Doble, A; Petitet, F | 1 |
| Fattman, CL; Hoyt, KR; Rajdev, S; Reynolds, IJ | 1 |
| Bettler, B; Mulle, C | 1 |
| Desai, MA; Monn, JA; Schoepp, DD; Valli, MJ | 1 |
| Balázs, R; Hack, N | 1 |
| Geiger, JR; Jonas, P; Koh, DS; Sakmann, B | 1 |
| Ballerini, L; Bracci, E; Nistri, A | 1 |
| Lodge, D; Palmer, AJ | 1 |
| May, PC; Robison, PM | 1 |
| Mayer, ML; Patneau, DK; Vyklicky, L | 1 |
| Mayer, ML; Wong, LA | 1 |
| Gallo, V; Holtzclaw, LA; Russell, JT | 1 |
| Mennerick, S; Que, J; Zorumski, CF | 1 |
| Glowinski, J; Williams, RJ | 1 |
| Acosta, S; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Fedele, E; Raiteri, M | 1 |
| Bacskai, B; Pleasure, D; Yoshioka, A | 1 |
| Ballyk, BA; Bath, CP; Bleakman, D; Bufton, HR; Kamboj, RK; Lodge, D; Palmer, AJ; Schoepp, DD; Sharpe, EF; Tarnawa, I; Woolley, ML | 1 |
| Cebers, G; Hou, YN; Liljequist, S; Terenius, L | 1 |
| Arai, A; Hennegriff, M; Kessler, M; Lynch, G; Mutneja, MS; Neve, RL; Rogers, G; Vanderklish, P | 1 |
| Gershon, MD; Kirchgessner, AL; Liu, MT; Rothstein, JD | 1 |
| Bristow, DR; Savidge, JR | 1 |
| Bonfanti, A; Pittaluga, A; Raiteri, M | 1 |
| Ankarcrona, M; Cebers, G; Liljequist, S; Zhivotovsky, B | 1 |
| Croucher, MJ; Patel, DR | 1 |
| Fontana, G; Gemignani, A; Marchese, S; Raiteri, M | 1 |
| Beart, PM; Cowen, MS | 1 |
| Ohno, K; Okada, M; Sakamoto, S; Tsutsumi, R; Yamaguchi, T | 1 |
| Daggett, LP; Deal, C; Hess, SD; Jachec, C; Johnson, EC; Lin, F; Rao, SP; Varney, MA; Veliçelebi, G | 1 |
| Matsumoto, N; Ohno, K; Okada, M; Tsutsumi, R; Yamaguchi, T | 1 |
| Dougherty, PM; Lenz, FA; Mittman, S | 1 |
| Horiuchi, K; Itoh, A; Itoh, T; Pleasure, D | 1 |
| Holmberg, L; Souverbie, F; Sundström, E | 1 |
| Costa, E; Guidotti, A; Impagnatiello, F; Longone, P; Mienville, JM | 1 |
| Carvalho, AP; Duarte, CB; Ferreira, IL | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Yasuda, S | 1 |
| Collingridge, GL; Parsons, CG; Rammes, G; Swandulla, D; Zeilhofer, HU | 1 |
| Akaike, N; Harata, N; Katayama, J | 1 |
| Geurtz, W; Hatt, H; Okada, T; Schultz, K; Weiler, R | 1 |
| Bristow, DR; Lock, EA; Savidge, JR; Sturgess, NC | 1 |
| Arvigo, D; Bonfanti, A; Pittaluga, A; Raiteri, M | 1 |
| Perkinton, MS; Sihra, TS; Williams, RJ | 1 |
| Akaike, N; Nabekura, J; Nakanishi, H; Noda, M | 1 |
| Cooke, IM; Duan, S | 1 |
| Trussell, LO; Turecek, R | 1 |
| Csillik-Perczel, V; Harsing, LG; Ling, I; Sólyom, S | 1 |
| Cebers, G; Kovács, AD; Liljequist, S | 1 |
| Bódi, I; Gueritaud, J; Kapus, G; Pataki, A; Székely, JI; Tarnawa, I | 1 |
| Arai, A; Kessler, M; Rogers, G | 1 |
| Addae, JI; Ali, N; Evans, SM; Stone, TW | 1 |
| Durkin, JP; Gendron, TF; MacLean, S; Mealing, G; Morley, P; Small, DL; Tremblay, R | 1 |
| Chen, M; Itoh, A; Itoh, T; Pleasure, D; Reddy, UR; Stern, JL | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Malva, JO; Mesquita, JF; Silva, AP | 1 |
| Higashiyama, A; Ishida, N; Kato, N; Morinobu, S; Yasuda, S | 1 |
| Closier, M; Iop, F; Lestage, P; Lockhart, B | 1 |
| Kondo, M; Okabe, S; Okado, H; Sumino, R | 1 |
| Bolshakov, KV; Buldakova, SL; Magazanik, LG; Tikhonov, DB | 1 |
| Brorson, JR; Ihle, EC; Patneau, DK; Robberecht, W; Vandenberghe, W | 1 |
| Chatton, JY; Magistretti, PJ; Marquet, P | 1 |
| Cunningham, LA; Partridge, LD; Smith, JP | 1 |
| Morsette, DJ; Sidorowicz, H; Sladek, CD | 1 |
| Croucher, MJ; Patel, DR; Young, AM | 1 |
| DeGregorio-Rocasolano, N; Gasull, T; Trullas, R | 1 |
| Jensen, JB; Lund, TM; Pickering, DS; Schousboe, A; Timmermann, DB | 1 |
| Allgaier, C; Fischer, W; Franke, H; Illes, P; Scheibler, P | 1 |
| Hartveit, E; Mørkve, SH; Veruki, ML | 1 |
| Frye, GD; Hsiao, SH | 1 |
| Korpi, ER; Lovinger, DM; Möykkynen, T | 1 |
| Gerber, G; Randic, M; Voitenko, N; Youn, D | 1 |
| Bruno, V; Caciagli, F; Caricasole, A; Caruso, A; Castiglione, M; Di Giorgi Gerevini, V; Marinelli, F; Melchiorri, D; Moretti, A; Nicoletti, F; Pozzilli, C; Tomassini, V | 1 |
| Cepeda, C; Hernández-Echeagaray, E; Levine, MS; Starling, AJ | 1 |
| Konishi, S; Rusakov, D; Saitow, F; Satake, S | 1 |
| Huang, SY; Liang, PJ; Liu, Y | 1 |
| Magistretti, PJ; Pellerin, L | 1 |
| Bennett, SA; Cheung, EC; Cregan, SP; Ferguson, KL; McIntosh, WC; Melanson-Drapeau, L; Park, DS; Slack, RS; Vanderluit, JL | 1 |
| André, VM; Cepeda, C; Gomez, Y; Levine, MS; Venegas, A | 1 |
| Clements, JM; Vanhoose, AM; Winder, DG | 1 |
| Eusebi, F; Fucile, S; Miledi, R | 1 |
| Baba, A; Chen, H; Jones, M; Kiedrowski, L; Kintner, DB; Matsuda, T; Sun, D | 1 |
| Addae, JI; Ali, N; Stone, TW; Youssef, FF | 1 |
| Frerking, M; Wondolowski, J | 1 |
| Di Prisco, S; Grilli, M; Marchi, M; Pittaluga, A; Summa, M | 1 |
| Bernardi, G; Berretta, N; Ledonne, A; Mango, D; Mercuri, NB | 1 |
| Fukui, K; Ishiwata, S; Nishikawa, T; Umino, A; Umino, M; Yorita, K | 1 |
| Bachurin, SO; Grigoriev, VV; Karlov, DS; Lavrov, MI; Palyulin, VA; Ustyugov, AA; Voronina, TA | 1 |
1 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and cyclothiazide
| Article | Year |
|---|---|
Review: neurotransmitter receptors. II. AMPA and kainate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cloning, Molecular; Ganglia, Spinal; Hippocampus; Humans; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Time Factors | 1995 |
92 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and cyclothiazide
| Article | Year |
|---|---|
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.
Topics: Animals; Cell Line; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Humans; Ligands; Molecular Structure; Oocytes; Pyrimidinones; Rats; Receptors, Glutamate; Spodoptera; Structure-Activity Relationship; Thiophenes; Xenopus laevis | 2008 |
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA | 2010 |
Cyclothiazide decreases [3H]AMPA binding to rat brain membranes: evidence that AMPA receptor desensitization increases agonist affinity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brain; Diuretics; Membranes; Radioligand Assay; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors; Solubility; Temperature; Tritium | 1993 |
Glial cells of the oligodendrocyte lineage express both kainate- and AMPA-preferring subtypes of glutamate receptor.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Blotting, Northern; Cell Line; Kainic Acid; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription, Genetic | 1994 |
Cyclothiazide potentiates agonist responses at human AMPA/kainate receptors expressed in oocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Cloning, Molecular; Humans; Kainic Acid; Oocytes; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Xenopus laevis | 1994 |
Cyclothiazide selectively potentiates AMPA- and kainate-induced [3H]norepinephrine release from rat hippocampal slices.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Drug Synergism; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tritium; Veratridine | 1994 |
Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Binding Sites; Binding, Competitive; Hippocampus; In Vitro Techniques; Isoquinolines; Kainic Acid; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrazoles | 1995 |
Cyclothiazide unmasks AMPA-evoked stimulation of [3H]-L-glutamate release from rat hippocampal synaptosomes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Carbachol; Diuretics; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Potassium; Presynaptic Terminals; Rats; Rats, Wistar; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical; Synaptosomes | 1994 |
Effects of non-NMDA receptor modulators on [3H] dopamine release from rat mesencephalic cells in primary culture.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Dopamine; Drug Synergism; In Vitro Techniques; Kainic Acid; Mesencephalon; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1995 |
Cyclothiazide modulates AMPA receptor-mediated increases in intracellular free Ca2+ and Mg2+ in cultured neurons from rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Drug Synergism; Glutamic Acid; Kainic Acid; Magnesium; Neurons; Prosencephalon; Rats; Receptors, AMPA | 1995 |
1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Memory; N-Methylaspartate; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1995 |
Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Calcium; Calcium Radioisotopes; Cell Survival; Cells, Cultured; Cerebellum; Cobalt; Concanavalin A; Excitatory Amino Acids; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Wheat Germ Agglutinins | 1995 |
Ca(2+)-permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium Channels; Dendrites; Diuretics; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Kinetics; Magnesium; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Chloride Symporter Inhibitors | 1995 |
Desensitization of AMPA receptors limits the amplitude of EPSPs and the excitability of motoneurons of the rat isolated spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Electric Stimulation; In Vitro Techniques; Motor Neurons; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synaptic Transmission; Tetrodotoxin | 1995 |
Cyclothiazide reverses AMPA receptor antagonism of the 2,3-benzodiazepine, GYKI 53655.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cerebral Cortex; Diuretics; Excitatory Amino Acid Antagonists; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1993 |
Cyclothiazide treatment unmasks AMPA excitotoxicity in rat primary hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Drug Synergism; Hippocampus; Ibotenic Acid; Kainic Acid; Neurotoxins; Rats | 1993 |
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Differential modulation by cyclothiazide and concanavalin A of desensitization at native alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Ganglia, Spinal; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Neurons; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
AMPA receptors shape Ca2+ responses in cortical oligodendrocyte progenitors and CG-4 cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Kainic Acid; Oligodendroglia; Quinoxalines; Receptors, AMPA; Time Factors | 1995 |
Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Benzothiadiazines; Calcium; Cells, Cultured; Cycloleucine; Evoked Potentials; Glutamic Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Virulence Factors, Bordetella; Wheat Germ Agglutinins | 1996 |
Cyclothiazide unmasks an AMPA-evoked release of arachidonic acid from cultured striatal neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Benzothiadiazines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Drug Synergism; Embryo, Mammalian; Kinetics; Mice; Neurons; Neurotoxins | 1996 |
Diazoxide and cyclothiazide convert AMPA-induced dark cell degeneration of Purkinje cells to edematous damage in the cerebellar slice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cerebellum; Diazoxide; Diuretics; Edema; Nerve Degeneration; Purkinje Cells; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporter Inhibitors | 1996 |
Desensitization of AMPA receptors and AMPA-NMDA receptor interaction: an in vivo cyclic GMP microdialysis study in rat cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cerebellum; Cyclic GMP; Dizocilpine Maleate; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1996 |
Pathophysiology of oligodendroglial excitotoxicity.
Topics: Acetylcysteine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aurintricarboxylic Acid; Benzothiadiazines; Biological Transport; Calcium; Cell Line; Cell Membrane; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Nerve Tissue Proteins; Oligodendroglia; Rats; Receptors, AMPA; RNA, Messenger | 1996 |
Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: stereospecificity and selectivity profiles.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Cell Line; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Humans; Kidney; Membrane Potentials; Molecular Structure; Neurons; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Recombinant Proteins; Spinal Cord; Structure-Activity Relationship; Transfection | 1996 |
Characterization of NMDA- and AMPA-induced enhancement of AP-1 DNA binding activity in rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Cerebellum; Dizocilpine Maleate; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kinetics; N-Methylaspartate; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Transcription Factor AP-1 | 1997 |
Stable expression of recombinant AMPA receptor subunits: binding affinities and effects of allosteric modulators.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Benzamides; Benzothiadiazines; Binding, Competitive; Blotting, Western; Cells, Cultured; Diuretics; Excitatory Amino Acid Agonists; Gene Expression; Kidney; Patch-Clamp Techniques; Receptors, AMPA; Recombinant Proteins; Sodium Chloride Symporter Inhibitors; Transfection; Tritium | 1997 |
Glutamatergic enteric neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Benzothiadiazines; Calcium; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hexamethonium; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Microscopy, Immunoelectron; Muscle, Smooth; Myenteric Plexus; Neurons; Nicotine; Organelles; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin | 1997 |
Distribution of Ca(2+)-permeable AMPA receptors among cultured rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cells, Cultured; Cerebellum; Culture Media; Culture Media, Serum-Free; Diuretics; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Manganese; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1997 |
Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cerebral Cortex; Choline; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Norepinephrine; Potassium; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Serotonin; Synaptosomes | 1997 |
AMPA neurotoxicity in cultured cerebellar granule neurons: mode of cell death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cell Death; Cells, Cultured; Cerebellum; Diuretics; Dose-Response Relationship, Drug; Models, Neurological; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporter Inhibitors | 1997 |
Evidence for a role of presynaptic AMPA receptors in the control of neuronal glutamate release in the rat forebrain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Benzothiadiazines; Binding, Competitive; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Neurons; Presynaptic Terminals; Prosencephalon; Rats; Rats, Wistar; Receptors, AMPA; Tetrodotoxin | 1997 |
Neuropeptide Y release from cultured hippocampal neurons: stimulation by glutamate acting at N-methyl-D-aspartate and AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antibody Specificity; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Neurons; Neuropeptide Y; Quinoxalines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1997 |
Cyclothiazide and AMPA receptor desensitization: analyses from studies of AMPA-induced release of [3H]-noradrenaline from hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Diuretics; Hippocampus; In Vitro Techniques; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Second Messenger Systems; Sodium Chloride Symporter Inhibitors; Tritium | 1998 |
The AMPA-receptor antagonist YM90K reduces AMPA receptor-mediated excitotoxicity in rat hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Diuretics; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1998 |
Pharmacological characterization of the human ionotropic glutamate receptor subtype GluR3 stably expressed in mammalian cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Binding, Competitive; Brain; Cells, Cultured; Diuretics; Electrophysiology; Excitatory Amino Acid Antagonists; Hippocampus; Humans; Kidney; Quinoxalines; Rats; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1998 |
Characterization of cyclothiazide-enhanced kainate excitotoxicity in rat hippocampal cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Embryo, Mammalian; Hippocampus; Kainic Acid; Rats; Rats, Wistar; Receptors, AMPA | 1998 |
Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Drug Synergism; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Macaca fascicularis; Male; N-Methylaspartate; Thalamic Nuclei | 1998 |
AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Channel Blockers; Cell Death; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Homeostasis; Humans; Kainic Acid; Membrane Potentials; Neurons; Neurotoxins; Nimodipine; Potassium; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Spider Venoms | 1998 |
NMDA and AMPA receptors evoke transmitter release from noradrenergic axon terminals in the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Dizocilpine Maleate; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Presynaptic Terminals; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1998 |
Changes in AMPA receptor-spliced variant expression and shift in AMPA receptor spontaneous desensitization pharmacology during cerebellar granule cell maturation in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Benzothiadiazines; Calcium; Cell Differentiation; Cells, Cultured; Cerebellum; Electrophysiology; Gene Expression Regulation, Developmental; Ion Channels; Neurons; Nitrendipine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA Editing; Sodium | 1998 |
Kainate-induced retina amacrine-like cell damage is mediated by AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium Radioisotopes; Cells, Cultured; Chickens; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Neuromuscular Depolarizing Agents; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1998 |
[Running fit and generalized tonic-clonic seizure are differently controlled by different subtype receptors in the brainstem].
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Brain Stem; Dizocilpine Maleate; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Agonists; Inferior Colliculi; N-Methylaspartate; Neuroprotective Agents; Propylthiouracil; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures | 1998 |
Expression of early hippocampal CA1 LTP does not lead to changes in AMPA-EPSC kinetics or sensitivity to cyclothiazide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Diuretics; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Kinetics; Long-Term Potentiation; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Sodium Chloride Symporter Inhibitors | 1999 |
Excitatory amino acid responses in relay neurons of the rat lateral geniculate nucleus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Concanavalin A; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Geniculate Bodies; Glutamic Acid; Glycine; Ionophores; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Nystatin; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1999 |
AMPA-preferring receptors with high Ca2+ permeability mediate dendritic plasticity of retinal horizontal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carps; Dark Adaptation; Dendrites; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Membrane Potentials; Microscopy, Electron; Neuronal Plasticity; Patch-Clamp Techniques; Receptors, AMPA; Receptors, Kainic Acid; Retina | 1999 |
Characterisation of kainate receptor mediated whole-cell currents in rat cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Concanavalin A; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Kinetics; Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Receptors, Kainic Acid; Spider Venoms | 1999 |
Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Ca(2+)-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen-activated protein kinase signaling cascade in neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Arachidonic Acid; Benzodiazepines; Benzothiadiazines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Genistein; GTP-Binding Proteins; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptors, AMPA; Signal Transduction; Virulence Factors, Bordetella; Wortmannin | 1999 |
AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Concanavalin A; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Microglia; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 2000 |
Glutamate and GABA activate different receptors and Cl(-) conductances in crab peptide-secretory neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Brachyura; Cells, Cultured; Chloride Channels; Chlorides; Concanavalin A; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quisqualic Acid; Receptors, AMPA; Receptors, GABA; Receptors, Glutamate | 2000 |
Control of synaptic depression by glutamate transporters.
Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission | 2000 |
Negative allosteric modulators of AMPA-preferring receptors inhibit [(3)H]GABA release in rat striatum.
Topics: Allosteric Site; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Corpus Striatum; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2000 |
Kainate receptor-mediated activation of the AP-1 transcription factor complex in cultured rat cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Cerebellum; Concanavalin A; Dimerization; Excitatory Amino Acid Antagonists; Isoquinolines; Kainic Acid; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tetrazoles; Transcription Factor AP-1 | 2000 |
Differential modulation of the GYKI 53784-induced inhibition of AMPA currents by various AMPA-positive modulators in cerebellar Purkinje cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Cerebellum; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Membrane Potentials; Piperidines; Purkinje Cells; Pyrrolidinones; Rats; Receptors, AMPA | 2000 |
The norbornenyl moiety of cyclothiazide determines the preference for flip-flop variants of AMPA receptor subunits.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Antihypertensive Agents; Benzothiadiazines; Binding Sites; Binding, Competitive; Cells, Cultured; Excitatory Amino Acid Agonists; Humans; Kidney; Pyrimidines; Rats; Receptors, AMPA; Tritium | 2000 |
NMDA-induced changes in a cortical network in vivo are prevented by AMPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Nerve Net; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Pharmacological and molecular characterization of glutamate receptors in the MIN6 pancreatic beta-cell line.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Biological Transport; Calcium; Cell Survival; DNA Primers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Islets of Langerhans; Kainic Acid; Protein Kinase C; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms; Tumor Cells, Cultured | 2000 |
Diminished calcium homeostasis and increased susceptibility to excitotoxicity of JS 3/16 progenitor cells after differentiation to oligodendroglia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Buffers; Calcium; Calcium-Transporting ATPases; Cell Death; Cell Differentiation; Cell Line; Homeostasis; Neurotoxins; Oligodendroglia; Phenotype; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stem Cells | 2000 |
Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]i changes in cultured rat hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Hippocampus; Kainic Acid; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, AMPA | 2000 |
Characterization of audiogenic-like seizures in naive rats evoked by activation of AMPA and NMDA receptors in the inferior colliculus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Suckling; Benzothiadiazines; Dizocilpine Maleate; Drug Administration Routes; Excitatory Amino Acid Antagonists; Female; Hypothyroidism; Inferior Colliculi; Injections, Intraventricular; Male; Maternal Exposure; N-Methylaspartate; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures | 2000 |
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium | 2000 |
A high GluR1 : GluR2 expression ratio is correlated with expression of Ca2+-binding proteins in rat forebrain neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Biological Transport; Calbindin 1; Calbindins; Calcium; Calcium Channel Blockers; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; In Situ Hybridization; Neurons; Parvalbumins; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; S100 Calcium Binding Protein G | 2000 |
Ca2+-dependent desensitization of AMPA receptors.
Topics: Adamantane; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Kainic Acid; Neurons; Nootropic Agents; Pyrrolidinones; Rats; Receptors, AMPA | 2000 |
AMPA receptor current density, not desensitization, predicts selective motoneuron vulnerability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Posterior Horn Cells; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2000 |
A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Biological Transport; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Kinetics; Mice; Models, Theoretical; N-Methylaspartate; Sodium; Symporters | 2000 |
Coupling of AMPA receptors with the Na(+)/Ca(2+) exchanger in cultured rat astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; COS Cells; Excitatory Amino Acid Agonists; Hippocampus; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Sodium-Calcium Exchanger | 2000 |
Role of non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophysial explants.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Glutamates; Hypothalamo-Hypophyseal System; Kainic Acid; Kinetics; Male; N-Methylaspartate; Organ Culture Techniques; Oxytocin; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 2001 |
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carbon Radioisotopes; Corpus Striatum; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Microdialysis; Nootropic Agents; Potassium; Presynaptic Terminals; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tritium | 2001 |
Overactivation of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate and N-methyl-D-aspartate but not kainate receptors inhibits phosphatidylcholine synthesis before excitotoxic neuronal death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cell Death; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Neurons; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2001 |
Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Benzothiadiazines; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flunarizine; Gene Expression Regulation, Developmental; Ion Channel Gating; Lanthanum; Macromolecular Substances; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nifedipine; omega-Conotoxins; Polyamines; Protein Subunits; Receptors, AMPA; Sodium; Sodium Channels; Sodium-Calcium Exchanger; Spermine; Tetrodotoxin | 2001 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Functional characteristics of non-NMDA-type ionotropic glutamate receptor channels in AII amacrine cells in rat retina.
Topics: Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Concanavalin A; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Membrane Potentials; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, Glutamate; Retina; Sodium | 2002 |
AMPA receptors on developing medial septum/diagonal band neurons are sensitive to early postnatal binge-like ethanol exposure.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Blotting, Western; Cells, Cultured; Central Nervous System Depressants; Diagonal Band of Broca; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Male; Membrane Potentials; Models, Animal; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2003 |
Ethanol inhibits alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function in central nervous system neurons by stabilizing desensitization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Substitution; Animals; Benzothiadiazines; Cells, Cultured; Central Nervous System; Central Nervous System Depressants; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Humans; Kainic Acid; Leucine; Membrane Potentials; Mice; Mice, Inbred C57BL; Mutation; Neurons; Pyramidal Cells; Receptors, AMPA; Tyrosine | 2003 |
Peripheral inflamation-induced increase of AMPA-mediated currents and Ca2+ transients in the presence of cyclothiazide in the rat substantia gelatinosa neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Signaling; Carrageenan; Excitatory Amino Acid Agonists; Female; In Vitro Techniques; Inflammation; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Substantia Gelatinosa | 2004 |
Testosterone amplifies excitotoxic damage of cultured oligodendrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcium; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression; Kainic Acid; L-Lactate Dehydrogenase; Neurotoxins; Oligodendroglia; Quinoxalines; Rats; Receptors, AMPA; Receptors, Androgen; Receptors, Kainic Acid; Testosterone; Time Factors | 2004 |
Modulation of AMPA currents by D2 dopamine receptors in striatal medium-sized spiny neurons: are dendrites necessary?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Calcium; Cells, Cultured; Corpus Striatum; Dendrites; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2004 |
AMPA receptor-mediated presynaptic inhibition at cerebellar GABAergic synapses: a characterization of molecular mechanisms.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Benzoxazines; Calcium; Calcium Channel Blockers; Cerebellum; Chelating Agents; Colforsin; Cyclopropanes; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Morpholines; Naphthalenes; Neural Inhibition; Neurons; Piperidines; Presynaptic Terminals; Pyrazoles; Rats; Rats, Wistar; Receptors, AMPA; Ryanodine; Synapses; Triazines; Triazoles | 2004 |
Role of Ca2+ store in AMPA-triggered Ca2+ dynamics in retinal horizontal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Signaling; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Agonists; Fura-2; Goldfish; Models, Biological; Neurons; Nonlinear Dynamics; Retina; Ryanodine | 2004 |
Ampakine CX546 bolsters energetic response of astrocytes: a novel target for cognitive-enhancing drugs acting as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Benzothiadiazines; Cell Separation; Cells, Cultured; Cerebellum; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; Hippocampus; Lactic Acid; Mice; Nootropic Agents; Piperidines; Receptors, AMPA | 2005 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
Altered cortical glutamate receptor function in the R6/2 model of Huntington's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Benzothiadiazines; Cerebral Cortex; Disease Models, Animal; Exons; Huntington Disease; Magnesium; Mice; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Pyramidal Cells; Receptors, Glutamate; Time Factors | 2006 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Calcineurin Inhibitors; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Egtazic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Isoproterenol; Long-Term Potentiation; Male; Marine Toxins; Mice; Mice, Inbred C57BL; N-Methylaspartate; Oxazoles; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Piperidines; Protein Phosphatase 1; Protein Phosphatase 2; Protein Processing, Post-Translational; Receptors, Adrenergic, beta-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2006 |
Effects of cyclothiazide on GluR1/AMPA receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Humans; Patch-Clamp Techniques; Receptors, AMPA | 2006 |
AMPA-mediated excitotoxicity in oligodendrocytes: role for Na(+)-K(+)-Cl(-) co-transport and reversal of Na(+)/Ca(2+) exchanger.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Cell Death; Cells, Cultured; Central Nervous System; Excitatory Amino Acid Agonists; Glutamic Acid; Membrane Transport Proteins; Mitochondria; Neurotoxins; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2007 |
AMPA receptor activation reduces epileptiform activity in the rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Bicuculline; Chlormethiazole; Diazepam; Electroencephalography; Epilepsy; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Neocortex; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2007 |
Subunit-dependent postsynaptic expression of kainate receptors on hippocampal interneurons in area CA1.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Baclofen; Benzothiadiazines; Biophysics; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Galactolipids; Hippocampus; In Vitro Techniques; Interneurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Thymine | 2009 |
Hippocampal AMPA autoreceptors positively coupled to NMDA autoreceptors traffic in a constitutive manner and undergo adaptative changes following enriched environment training.
Topics: Adaptation, Physiological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Benzothiadiazines; Carrier Proteins; Cytoskeletal Proteins; D-Aspartic Acid; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Environment; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Guanylate Kinases; Hippocampus; Immunoprecipitation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; N-Ethylmaleimide-Sensitive Proteins; N-Methylaspartate; Nuclear Proteins; Presynaptic Terminals; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptophysin; Synaptosomes; Tritium | 2011 |
A continuous high frequency stimulation of the subthalamic nucleus determines a suppression of excitatory synaptic transmission in nigral dopaminergic neurons recorded in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Bicuculline; Biophysics; Dopaminergic Neurons; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; In Vitro Techniques; Neural Pathways; Rats; Rats, Wistar; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission | 2012 |
Modulation of extracellular d-serine content by calcium permeable AMPA receptors in rat medial prefrontal cortex as revealed by in vivo microdialysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Area Under Curve; Benzothiadiazines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Extracellular Fluid; Fluorometry; Gas Chromatography-Mass Spectrometry; Male; Microdialysis; Prefrontal Cortex; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Serine; Spermine; Time Factors | 2013 |
Novel Positive Allosteric Modulators of AMPA Receptors Based on 3,7-Diazabicyclo[3.3.1]nonane Scaffold.
Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Rats, Wistar; Receptors, AMPA | 2020 |