alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and aniracetam

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with aniracetam in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (52.38)18.2507
2000's8 (38.10)29.6817
2010's1 (4.76)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
England, PM; Fleming, JJ1
Ozawa, S; Takeuchi, T; Tsuzuki, K1
Abe, M; Iino, M; Ozawa, S1
Ambros-Ingerson, J; Larson, J; Lynch, G; Xiao, P1
Hatt, H; Kruse, M; Schmidt, KF1
Mayer, ML; Wong, LA1
Iino, M; Ozawa, S1
Fushiki, S; Matsumoto, K; Nagata, A1
Chapman, AG; Chimirri, A; Constanti, A; De Sarro, A; De Sarro, G; Gitto, R; Giusti, P; Grasso, S; Libri, V; Quartarone, S; Zappalà, M1
Chimirri, A; Constanti, A; De Sarro, A; De Sarro, G; Gitto, R; Libri, V; Quartarone, S; Zappalà, M1
Arvigo, D; Bonfanti, A; Pittaluga, A; Raiteri, M1
Baraldi, M; De Micheli, C; De Sarro, A; De Sarro, G; Grasso, S; Micale, N; Puia, G; Zappalà, M1
Black, MD; Hanak, SE; Schilp, DE; Sorensen, SM; Wettstein, JG; Wotanis, J1
Kurasawa, M; Nakamura, K; Shirane, M1
Bódi, I; Gueritaud, J; Kapus, G; Pataki, A; Székely, JI; Tarnawa, I1
Closier, M; Iop, F; Lestage, P; Lockhart, B1
Bolshakov, KV; Buldakova, SL; Magazanik, LG; Tikhonov, DB1
Bevacqua, F; Chimirri, A; De Sarro, A; De Sarro, G; Gitto, R; Quartarone, S; Rizzo, M; Zappalà, M1
Croucher, MJ; Patel, DR; Young, AM1
Bahr, BA; Owens, K; Rogers, G; Sinnarajah, S; Suppiramaniam, V; Vodyanoy, V; Yilma, S1
Reeta, KH; Sharma, H; Sharma, U; Singh, S; Suri, V1

Other Studies

21 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and aniracetam

ArticleYear
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
    Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4

    Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA

2010
Agonist- and subunit-dependent potentiation of glutamate receptors by a nootropic drug aniracetam.
    Brain research. Molecular brain research, 1992, Volume: 16, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Psychotropic Drugs; Pyrrolidinones; Rats; Receptors, Glutamate; Xenopus laevis

1992
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
    Neuroscience research, 1991, Volume: 12, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses

1991
LTP changes the waveform of synaptic responses.
    Synapse (New York, N.Y.), 1991, Volume: 9, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Pyrrolidinones; Rats; Receptors, AMPA; Receptors, Neurotransmitter; Synapses

1991
Dopamine alters glutamate receptor desensitization in retinal horizontal cells of the perch (Perca fluviatilis).
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-16, Volume: 91, Issue:17

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Dopamine; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Perches; Pyrrolidinones; Quisqualic Acid; Receptors, Glutamate; Retina; Time Factors

1994
Differential modulation by cyclothiazide and concanavalin A of desensitization at native alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- and kainate-preferring glutamate receptors.
    Molecular pharmacology, 1993, Volume: 44, Issue:3

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Concanavalin A; Ganglia, Spinal; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Neurons; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid

1993
Two distinct types of AMPA responses in cultured rat hippocampal neurons.
    Neuroscience letters, 1993, Jun-11, Volume: 155, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Hippocampus; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Membrane Potentials; Neurons; Pyrrolidinones; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid

1993
Neurite outgrowth of murine cerebellar granule cells can be enhanced by aniracetam with or without alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA).
    Neuroscience letters, 1995, Oct-27, Volume: 199, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Immunohistochemistry; Mice; Mice, Inbred Strains; Neurites; Pyrrolidinones

1995
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists.
    Journal of medicinal chemistry, 1997, Apr-11, Volume: 40, Issue:8

    Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepinones; Convulsants; Mice; Mice, Inbred DBA; Pentylenetetrazole; Pyrrolidinones; Receptors, AMPA; Seizures

1997
3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: a new class of AMPA receptor antagonists.
    Journal of medicinal chemistry, 1998, Aug-27, Volume: 41, Issue:18

    Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepines; Convulsants; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; Motor Activity; Olfactory Pathways; Patch-Clamp Techniques; Pentylenetetrazole; Pyrrolidinones; Rats; Receptors, AMPA; Seizures; Structure-Activity Relationship; Thiones

1998
Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heterocyclic Compounds; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Nootropic Agents; Norepinephrine; Piperidines; Pyrrolidinones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Tritium

1999
Synthesis and anticonvulsant activity of novel and potent 2,3-benzodiazepine AMPA/kainate receptor antagonists.
    Journal of medicinal chemistry, 1999, Oct-21, Volume: 42, Issue:21

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cells, Cultured; Convulsants; Drug Evaluation, Preclinical; Electroshock; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; Mice, Inbred DBA; Motor Activity; Neurons; Patch-Clamp Techniques; Pentylenetetrazole; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Seizures

1999
Effect of AMPA receptor modulators on hippocampal and cortical function.
    European journal of pharmacology, 2000, Apr-07, Volume: 394, Issue:1

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Piperidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA

2000
Impulsivity and AMPA receptors: aniracetam ameliorates impulsive behavior induced by a blockade of AMPA receptors in rats.
    Brain research, 2000, Apr-17, Volume: 862, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anxiety; Behavior, Animal; Conditioning, Operant; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Impulsive Behavior; Male; Motor Activity; Nootropic Agents; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA

2000
Differential modulation of the GYKI 53784-induced inhibition of AMPA currents by various AMPA-positive modulators in cerebellar Purkinje cells.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Cerebellum; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Membrane Potentials; Piperidines; Purkinje Cells; Pyrrolidinones; Rats; Receptors, AMPA

2000
(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Frontal Lobe; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Tetrodotoxin; Tritium

2000
Ca2+-dependent desensitization of AMPA receptors.
    Neuroreport, 2000, Sep-11, Volume: 11, Issue:13

    Topics: Adamantane; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Animals, Newborn; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Kainic Acid; Neurons; Nootropic Agents; Pyrrolidinones; Rats; Receptors, AMPA

2000
Synthesis and evaluation of pharmacological and pharmacokinetic properties of 11H-[1,2,4]triazolo[4,5-c][2,3]benzodiazepin-3(2H)-ones.
    Journal of medicinal chemistry, 2000, Dec-14, Volume: 43, Issue:25

    Topics: Acoustic Stimulation; Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzodiazepines; Chromatography, High Pressure Liquid; Electroshock; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred DBA; Motor Activity; Pentylenetetrazole; Pyrrolidinones; Receptors, AMPA; Seizures; Structure-Activity Relationship

2000
Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
    Neuroscience, 2001, Volume: 102, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Calcium; Carbon Radioisotopes; Corpus Striatum; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Microdialysis; Nootropic Agents; Potassium; Presynaptic Terminals; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Tritium

2001
Member of the Ampakine class of memory enhancers prolongs the single channel open time of reconstituted AMPA receptors.
    Synapse (New York, N.Y.), 2001, Volume: 40, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain; Dioxoles; Excitatory Amino Acid Agonists; Ion Channels; Memory; Neurons; Nootropic Agents; Piperidines; Pyridines; Pyrrolidinones; Rats; Receptors, AMPA; Subcellular Fractions; Synaptic Membranes; Time Factors

2001
AMPA receptor modulation through sequential treatment with perampanel and aniracetam mitigates post-stroke damage in experimental model of ischemic stroke.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Inflammatory Agents; Infarction, Middle Cerebral Artery; Ischemic Stroke; Models, Theoretical; Neuroprotective Agents; Rats; Receptors, AMPA; Stroke

2023