alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with 6-cyano-7-nitroquinoxaline-2,3-dione in 300 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (2.33) | 18.7374 |
| 1990's | 183 (61.00) | 18.2507 |
| 2000's | 83 (27.67) | 29.6817 |
| 2010's | 24 (8.00) | 24.3611 |
| 2020's | 3 (1.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cox, JA; Seeburg, PH; Stein, E; Verdoorn, TA | 1 |
| Annala, AJ; Baudry, M; Thompson, RF; Tocco, G | 1 |
| Fedorov, NB; Reymann, KG; Screbitsky, VG | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Yamada, S; Yoshimura, M | 1 |
| Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Baudry, M; Shahi, K | 1 |
| Fink, K; Göthert, M; Schultheiss, R | 1 |
| Johnston, MV; McDonald, JW; Trescher, WH | 1 |
| Dutton, GR; Rogers, KL | 1 |
| Parks, TN; Zhou, N | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Baudry, M; Massicotte, G; Standley, S; Thompson, RF; Tocco, G | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 2 |
| Gallo, V; Levi, G; Patrizio, M | 2 |
| Monyer, H; Seeburg, PH; Wisden, W | 1 |
| Chiu, SY; Jensen, AM | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Artola, A; Kato, N; Singer, W | 1 |
| Cha, JJ; Makowiec, RL; Penney, JB; Young, AB | 1 |
| Eaton, SA; Roberts, WA; Salt, TE | 1 |
| Abe, M; Iino, M; Ozawa, S | 1 |
| Jacques-Berg, W; Patel, AJ; Rodriguez, J | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Coderre, TJ; Melzack, R | 1 |
| Christenson, J; Grillner, S | 1 |
| Audinat, E; Crepel, F; Geoffroy, M; Hamon, B; Kado, RT; Lambolez, B; Rossier, J | 1 |
| Franke, C; Hatt, H; Rosenheimer, JL; Smith, DO; Zufall, F | 1 |
| Berge, OG; Hole, K; Lund, A; Mjellem-Joly, N | 1 |
| Cha, JH; Drejer, J; Honoré, T; Nielsen, EO; Young, AB | 1 |
| Gallo, V; Giovannini, C; Levi, G | 1 |
| Glaum, SR; Holzwarth, JA; Miller, RJ | 1 |
| Ishida, M; Ishihara, T; Nakagawa, Y; Saitoh, K; Shinozaki, H | 1 |
| Dawson, TL; Dingledine, R; Nicholas, RA | 1 |
| Barnard, EA; Henley, JM | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Courtney, MJ; Lambert, JJ; Nicholls, DG | 1 |
| Bockaert, J; Charpentier, N; Dumuis, A; Pin, JP; Sebben, M | 1 |
| Thomson, AM | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Collingridge, GL; Davies, SN; Lester, RA; Reymann, KG | 1 |
| Blake, JF; Brown, MW; Collingridge, GL; Yates, RG | 1 |
| Drejeŕ, J; Honore, T; Nielsen, EO; Nielsen, M | 1 |
| Aizenman, E; Karschin, A; Lipton, SA | 1 |
| Baraban, JM; Stratton, KR; Worley, PF | 1 |
| Ambrosini, A; Barnard, EA; Henley, JM; Krogsgaard-Larsen, P | 1 |
| Davies, SN; Drejer, J; Fletcher, EJ; Honoré, T; Jacobsen, P; Lodge, D; Nielsen, FE | 1 |
| Biggs, CS; Fowler, LJ; Maione, S; Rossi, F; Whitton, PS | 1 |
| Berger, I; Gillis, RA; Kelly, M; Magee, S; McManigle, JE; Norman, WP; Panico, WH; Taveira DaSilva, AM; Vitagliano, S | 1 |
| Bernardi, G; Bonci, A; Calabresi, P; Mercuri, NB; Stratta, F | 1 |
| Sheardown, MJ | 1 |
| Izquierdo, I; Medina, JH | 1 |
| Lerma, J; Mellström, B; Naranjo, JR; Paternain, AV | 1 |
| Kuraishi, Y; Okano, K; Satoh, M | 1 |
| Fedorov, NB; Reymann, KG | 1 |
| Boddeke, H; Figurov, A; Muller, D | 1 |
| Jahr, CE; Tong, G | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM; Shope, SB | 1 |
| Gyevai, A; Mike, A; Osipenko, O; Vizi, ES | 1 |
| Cull-Candy, SG; Wyllie, DJ | 1 |
| Hardy, M; Pleasure, D; Pleasure, J; Shi, QY; Tang, CM; Williams, M; Younkin, D | 1 |
| Jedema, HP; Moghaddam, B | 1 |
| Herrera, AJ; Osborne, NN | 1 |
| Hall, RA; Kessler, M; Lynch, G | 1 |
| Akopian, A; Krizaj, D; Witkovsky, P | 1 |
| Bianchin, M; Izquierdo, I; Medina, JH; Quillfeldt, JA; Schmitz, PK; Walz, R; Zanatta, MS | 1 |
| Bruno, VM; Choi, DW; Dugan, LL; Giffard, RG; Goldberg, MP | 1 |
| Aletras, AJ; Kouvelas, ED; Papaioannou, D; Sivvas, E; Voukelatou, G | 1 |
| Ebert, B; Krogsgaard-Larsen, P; Lenz, SM; Lund, TM; Madsen, U | 1 |
| Freund, WD; Reddig, S | 1 |
| Herrero, JF | 1 |
| Madamba, SG; Nie, Z; Siggins, GR | 1 |
| Kouvelas, ED; Mitsacos, A; Zavitsanou, K | 1 |
| Oja, SS; Saransaari, P | 2 |
| Carvalho, AP; Carvalho, CM; Duarte, CB; Ferreira, IL; Santos, PF | 1 |
| Biggs, CS; Fowler, LJ; Maione, S; Whitton, PS | 1 |
| Jonas, P; Sakmann, B; Spruston, N | 1 |
| Andersen, PH; Jørgensen, M; Tygesen, CK | 1 |
| Köhling, R; Lücke, A; Moskopp, D; Speckmann, EJ; Straub, H; Wassmann, H | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Cunha, RA; Malva, JO; Ribeiro, JA | 1 |
| Dowling, JE; Grant, GB | 1 |
| Acciarri, N; Beani, L; Bianchi, C; Calo, G; Fabrizi, A; Ferraro, L; Morari, M; Piazza, G | 1 |
| Dev, KK; Henley, JM; Honoré, T | 1 |
| Balcar, VJ; Killinger, S; Li, Y | 1 |
| Hu, B; Nissen, R; Renaud, LP | 1 |
| Drejer, J; Johansen, TH; Nielsen, EO; Wätjen, F | 1 |
| Herron, C; Hjelmstad, GO; Malenka, RC; Nicoll, RA; Selig, DK | 1 |
| Henley, JM | 1 |
| Baudry, M; Massicotte, G; Standley, S; Thompson, RF; Tocco, G; Tourigny, MF | 1 |
| Hill, JM; Kaufman, MP; Wong, MK | 1 |
| Beaver, KM; Hawkins, LM; Jane, DE; Roberts, PJ; Sunter, DC; Taylor, PM | 1 |
| Steele, RJ; Stewart, MG | 1 |
| Collins, GG | 1 |
| Baudry, M; Hall, RA; Kessler, M; Lynch, G; Massicotte, G | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Lanius, RA; Pasqualotto, BA; Shaw, CA | 1 |
| Hensley, SH; Wu, SM; Yang, XL | 1 |
| Callaway, EM; Katz, LC | 1 |
| Lücke, T; Neugebauer, V; Schaible, HG | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Constantine-Paton, M; Hickmott, PW | 1 |
| Hammerland, LG; Parks, TN; Zhou, N | 1 |
| Burns, LH; Isacson, O; Sato, K; Wüllner, U | 1 |
| Baraban, JM; Fiore, RS; Murphy, TH; Pelech, SL; Sanghera, JS | 1 |
| Crowley, WR; Parker, SL | 2 |
| Bernardi, G; Calabresi, P; Fedele, E; Fontana, G; Mercuri, NB; Pisani, A; Raiteri, M | 1 |
| Bortolotto, ZA; Collingridge, GL | 1 |
| Pidoplichko, VI; Reymann, KG; Wilsch, VW | 1 |
| Karpefors, M; Niu, YP; Wigström, H; Xiao, MY | 2 |
| Altemus, KL; Cepeda, C; Colwell, CS; Levine, MS | 1 |
| Giovannucci, DR; Stuenkel, EL | 1 |
| Jedema, HP; Moghddam, B | 1 |
| Auth, F; DeBoer, P; Moor, E; Westerink, BH | 1 |
| Buisson, A; Choi, DW; Yu, SP | 1 |
| Kaneko, A; Sasaki, T | 1 |
| Parks, TN; Taylor, DA; Zhou, N | 1 |
| Bisset, GW; Fairhall, KM | 1 |
| Iino, M; Isa, T; Itazawa, S; Ozawa, S; Tsuzuki, K | 1 |
| Barrios, M; Liljequist, S | 1 |
| Carvalho, AP; Carvalho, CM; Malva, JO | 1 |
| Cotton, DB; Hallak, M; Irtenkauf, SM | 1 |
| Hand, GA; Ordway, GA; Wilson, LB | 1 |
| Glowinski, J; Pirot, S; Thierry, AM | 1 |
| Feltz, P; Jo, YH; Poisbeau, P; Schlichter, R | 1 |
| Hori, Y; Kanda, K | 1 |
| Bhagavatula, LS; Sastry, BR | 1 |
| Caine, SB; Swerdlow, NR; Wan, FJ | 1 |
| Cox, C; McCoy, L; Richfield, EK | 2 |
| Ishihara, K; Sakai, N; Sasa, M; Tanaka, C; Ujihara, H | 1 |
| Kombian, SB; Pittman, QJ; Saleh, TM; Zidichouski, JA | 1 |
| Alici, K; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Altermatt, HJ; Arnold, A; Ehrenberger, K; Felix, D; Frenz, M; Pratisto, H; Weber, HP | 1 |
| Matute, C; Sanchez-Gomez, MV | 1 |
| Deitmer, JW; Munsch, T | 1 |
| Bhardwaj, A; Hanley, DF; Ichord, RN; Koehler, RC; Northington, FJ; Traystman, RJ | 1 |
| Inoue, T; Ito, KI; Kato, H; Mikoshiba, K; Miyakawa, H | 1 |
| Gershon, MD; Kirchgessner, AL; Liu, MT; Rothstein, JD | 1 |
| Baudry, M; Bi, X; Gellerman, DM | 1 |
| Frandsen, A; Griffiths, R; Malcolm, C; Meredith, C; Ritchie, L; Rumsby, P; Schousboe, A; Scott, M | 1 |
| Beart, PM; Cheung, NS; Larm, JA | 1 |
| Bunnett, NW; Grady, EF; Martínez, V; Marvizón, JC; Mayer, EA | 1 |
| Katz, LC; Roerig, B | 1 |
| Illes, P; Nieber, K; Poelchen, W | 1 |
| Cory-Slechta, DA; McCoy, L; Richfield, EK | 1 |
| Członkowska, A; Płaźnik, A; Siemiatkowski, M | 1 |
| Hirata, A; Kamakura, K; Kwak, S; Nagata, N; Nakamura, R | 1 |
| Hirata, A; Kamakura, K; Kwak, S; Nakamura, R | 1 |
| Benjamin, PR; Brierley, MJ; Yeoman, MS | 1 |
| Bekkers, JM; Clements, JD; Reid, CA | 1 |
| Hoffman, KB; Kessler, M; Lam, L; Lynch, G; Ta, J | 1 |
| Horiuchi, K; Itoh, A; Itoh, T; Pleasure, D | 1 |
| Niu, YP; Wigström, H; Xiao, MY | 1 |
| Mifflin, SW; Zhang, J | 1 |
| Baudry, M; Hauge, SA; Thompson, RF; Tracy, JA | 1 |
| Johnson, AK; Xu, Z | 1 |
| Chandler, SH; Del Negro, CA | 1 |
| Mathé, JM; Nomikos, GG; Schilström, B; Svensson, TH | 1 |
| Calejesan, AA; Huettner, JE; Kim, SJ; Li, P; Wilding, TJ; Zhuo, M | 1 |
| Fryer, HJ; Kalb, RG; Knox, RJ; Strittmatter, SM | 1 |
| Gwag, BJ; Joe, E; Kim, EY; Kim, YH; Koh, JY; Sohn, S | 1 |
| D'Hooge, R; De Deyn, PP; Raes, A; Van Bogaert, PP; Van de Vijver, G | 1 |
| Hargreaves, KM; Jackson, DL | 1 |
| Marshall, KC; Pelkey, KA | 1 |
| Inoue, T; Murphy, DD; Pozzo-Miller, LD | 1 |
| McCarthy, KD; Shelton, MK | 1 |
| Almazan, G; Larocca, JN; Liu, HN | 1 |
| Strahlendorf, HK; Strahlendorf, JC | 1 |
| Chen, X; Kombian, SB; Pittman, QJ; Zidichouski, JA | 1 |
| Lu, SM; Yeh, HH | 1 |
| Kleinfeld, D; Kristan, WB; Wessel, R | 1 |
| Fukaya, M; Hashimoto, K; Kano, M; Qiao, X; Sakimura, K; Watanabe, M | 1 |
| Hirano, T; Murashima, M | 1 |
| Chan, PH; Keinänen, R; Koistinaho, J; Tikka, T; Vartiainen, N | 1 |
| Cornish, JL; Duffy, P; Kalivas, PW | 1 |
| Arnold, T; Ehrenberger, K; Felix, D; Kleinlogel, S; Oestreicher, E | 1 |
| Chai, CY; Chen, SY | 1 |
| Chouvet, G; Dugast, C; Schmitt, P; Souliere, F | 1 |
| Kruman, II; Mattson, MP; Pedersen, WA; Springer, JE | 1 |
| Ballanyi, K; Kulik, A; Metzger, F; Sendtner, M | 1 |
| Cruise, L; Fuller, G; Ho, LK; Morris, BJ; Veitch, K | 2 |
| Connaughton, VP; Nelson, R | 1 |
| Arnold, A; Felix, D; Knipper, M; Oestreicher, E; Zenner, HP | 1 |
| Addae, JI; Ali, N; Evans, SM; Stone, TW | 1 |
| Durkin, JP; Gendron, TF; MacLean, S; Mealing, G; Morley, P; Small, DL; Tremblay, R | 1 |
| Akiba, I; Barsoumian, EL; Iizuka, M; Imoto, K; Nishimura, S; Wakamori, M | 2 |
| Caicedo, A; Jafri, MS; Roper, SD | 1 |
| Haga, M; Kinoshita, M; Moriyama, Y; Otsuka, M; Takeda, M; Tsuboi, S; Yamada, H | 1 |
| Chatton, JY; Magistretti, PJ; Marquet, P | 1 |
| Dobbertin, A; Gervais, A; Glowinski, J; Mallat, M | 1 |
| Isokawa, M | 1 |
| Morsette, DJ; Sidorowicz, H; Sladek, CD | 1 |
| Akaike, A; Honda, K; Inoue, R; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Inoue, N; Nakayama, T; Soga, TM | 1 |
| Ai, J; Jardemark, KE; Ninan, I; Wang, RY | 1 |
| Chvátal, A; Jendelová, P; Syková, E; Vargová, L | 1 |
| Huang, L; Pallas, SL | 1 |
| Hoya, N; Inoue, Y; Kanzaki, J; Ogawa, K; Takiguchi, Y | 1 |
| Hirose, K; Iino, M; Kakizawa, S; Okubo, Y | 1 |
| Lu, SM; Yeh, HH; Zecevic, N | 1 |
| Ciotti, MT; Eusebi, F; Limatola, C; Mercanti, D; Santoni, A | 1 |
| Cartier, L; Infante, C; Motles, E | 1 |
| Alberdi, E; Marino, A; Matute, C; Sánchez-Gómez, MV | 1 |
| Allgaier, C; Fischer, W; Franke, H; Illes, P; Scheibler, P | 1 |
| Chiang, AS; Lin, SC; Liu, HP; Pszczolkowski, MA | 1 |
| Colwell, CS; Itri, J; Michel, S | 1 |
| Di Gennaro, G; Esposito, V; Eusebi, F; Giangaspero, F; Miledi, R; Mileo, AM; Onorati, P; Palma, E; Quarato, P; Scoppetta, C; Trettel, F | 1 |
| Akaike, N; Carp, JS; Carpenter, DO; Hori, N | 1 |
| Ali, S; Back, SA; Dai, W; Follett, PL; Fu, J; Gan, XD; Jensen, FE; Rosenberg, PA; Sanchez, RM; Segal, MM; Volpe, JJ | 1 |
| Metzner, W; Smotherman, M; Zhang, S | 1 |
| Chai, CY; Hong, LZ | 1 |
| Díaz-Trelles, R; Fernández-Sánchez, MT; Novelli, A | 1 |
| Le Roux, PD; Monnerie, H; Shashidhara, S | 1 |
| De, A; Krueger, JM; Simasko, SM | 1 |
| Gonzaga, J; Hettes, SR; Heyming, TW; Perez, S; Stanley, BG; Wolfsohn, S | 1 |
| Inoue, T; Kuruma, A; Mikoshiba, K | 1 |
| Bredt, DS; Fukata, M; Nicoll, RA; Tomita, S | 1 |
| Jones, TL; Sorkin, LS | 1 |
| Dawkins, R; Sewell, WF | 1 |
| Cepeda, C; Hernández-Echeagaray, E; Levine, MS; Starling, AJ | 1 |
| Hu, B; Sun, SG; Tong, ET | 1 |
| de Lima, AD; Opitz, T; Voigt, T | 1 |
| Bevilaqua, LR; Bonini, JS; Cammarota, M; Izquierdo, N; Medina, JH; Rossatto, JI | 1 |
| Hemby, SE; Joëls, M; Verkuyl, JM | 1 |
| Shimogori, H; Yamashita, H | 1 |
| Barros, LF; Loaiza, A; Porras, OH | 1 |
| Bringmann, A; Klaus, C; Reichenbach, A; Rillich, K; Syková, E; Uckermann, O; Ulbricht, E; Vargová, L; Weick, M; Wiedemann, P | 1 |
| Balthazart, J; Cornil, CA; Motte, P; Seutin, V | 1 |
| Anderson, AJ; Garraway, SM; Mendell, LM | 1 |
| Jung, SJ; Kim, DK; Kim, J; Kim, SJ; Kim, YS | 1 |
| Chen, L; Chow, BK; Lee, SM; Yung, WH | 1 |
| Takemoto, Y | 1 |
| Chergui, K; Greengard, P; Svenningsson, P | 1 |
| Haas, HS; Heintz, E; Ingolic, E; Pfragner, R; Schauenstein, K; Siegl, V | 1 |
| Zheng, S; Zuo, Z | 1 |
| Coons, S; Ellsworth, K; Johnson, E; Kerrigan, JF; Kim, DY; Lue, LF; Nowak, L; Rekate, H; Rho, JM; St John, PA; Wu, J; Xu, L | 1 |
| Kartelija, G; Radenović, L; Selaković, V | 1 |
| Baillien, M; Ball, GF; Balthazart, J | 1 |
| Galik, J; Gerber, G; Park, YK; Randić, M; Voitenko, N; Youn, DH | 1 |
| Arai, AC; Kessler, M | 1 |
| Kamiyama, T; Sakurai, M; Yoshioka, N | 1 |
| Gonzalez-Islas, C; Wenner, P | 1 |
| Kovalchuk, Y; Meier, SD; Rose, CR | 1 |
| Dolman, NP; Ghosal, A; Jane, DE; Mayer, ML | 1 |
| Johns, RA; Skinner, J; Su, Q; Tao, F | 1 |
| Choi, HC; Eun, BL; Kim, H; Kim, HJ; Kim, IH; Kim, SK; Lim, JH; Noh, MR; Park, SK; Sun, W | 1 |
| Huang, J; Marszalec, W; Narahashi, T; Toth, PT; Yeh, JZ; Zhao, X | 1 |
| McCulloch, J; Milne, S; O'Neill, MJ; Sharkey, J; Voss, OP | 1 |
| Addae, JI; Ali, N; Stone, TW; Youssef, FF | 1 |
| Fatehi, M; Fatehi-Hassanabad, Z | 1 |
| Han, P; Nakanishi, ST; Tran, MA; Whelan, PJ | 1 |
| Bargas, J; Galarraga, E; Guzman, JN; Lopez-Huerta, VG; Tecuapetla, F | 1 |
| Ampagoomian, D; Beique, JC; Faraday, N; Gozen, O; Huganir, R; Ikeda, M; Lowenstein, CJ; Martin, TV; Mason, E; Morrell, CN; Rothstein, J; Sprengel, R; Sun, H; Swaim, AM; Thompson, LE | 1 |
| Kass-Simon, G; Scappaticci, AA | 1 |
| Fu, WM; Lin, TH; Tang, CH; Wu, MY; Yang, RS | 1 |
| Burrell, BD; Li, Q | 1 |
| Mir, S; Peever, JH; Schwarz, PB; Yee, N | 1 |
| Hartveit, E; Oltedal, L; Veruki, ML | 1 |
| Acker-Palmer, A; Essmann, CL; Geiger, JC; Klein, R; Martinez, E; Stein, V; Traut, MH; Zimmer, M | 1 |
| Biondolillo, JW; King, MS; Williams, LA | 1 |
| Gean, PW; Lin, HC; Mao, SC; Su, CL | 1 |
| Abbas, AK; Afanasenkau, D; Huang, FS; Li, R; Wigström, H | 1 |
| Fujimoto, I; Kasai, N; Ramanujan, CS; Ryan, JF; Shimada, A; Torimitsu, K | 1 |
| Gonzaga, WJ; Hettes, SR; Heyming, TW; Nguyen, JK; Perez, S; Stanley, BG | 1 |
| Jackson, MF; Li, HB; Macdonald, JF; Orser, BA; Salter, MW; Trepanier, C; Yang, K | 1 |
| Hall, BJ; Patrick, GN; Schwarz, LA | 1 |
| Colledge, WH; d'Anglemont de Tassigny, X; Herbison, AE; Liu, X; Millar, R; Petersen, SL; Porteous, R | 1 |
| Kelley, BG; Luoma, JI; Mermelstein, PG | 1 |
| Catenaccio, V; Jantos, H; Monti, JM; Xavier, S | 1 |
| Bernardi, G; Berretta, N; Ledonne, A; Mango, D; Mercuri, NB | 1 |
| Gocel, J; Larson, J | 1 |
| Herbison, AE; Lee, K; Liu, X | 1 |
| Grau, JW; Hoy, KC; Huie, JR | 1 |
| Guo, J; Han, W; Ong, WY; Pang, ZP; Qiu, W; Seah, CJ; Soh, SL; Wei, S; Yang, W | 1 |
| Bachtell, RK; Hobson, BD; Levis, SC; Monteggia, LM; Neve, RL; O'Neill, CE; Self, DW | 1 |
| Chen, D; Ding, L; Gao, R; Gao, XY; Kang, YM; Wang, JJ; Zhang, LL; Zhu, GQ | 1 |
| Du, P; Feng, H; Hu, R; Hu, SL; Li, F | 1 |
| Chen, PC; Heinzelmann, G; Kuyucak, S | 1 |
| Fu, X; Gao, J; Hou, L; Liang, Y; Luo, X; Ning, Q; Tian, F; Ying, Y | 1 |
| Datta, D; Ermentrout, GB; Fish, KN; Gonzalez-Burgos, G; Hammond, M; Hoftman, G; Lewis, DA; Miyamae, T; Pafundo, DE; Rotaru, DC; Sampson, AR; Yoshino, H; Zhang, Y | 1 |
| Johnson, KM; Kim, J; Timpe, JM; Wang, CZ | 1 |
| Akbarali, HI; Bowers, MS; Fitting, S; Hauser, KF; Knapp, PE; Marks, WD; Zou, S | 1 |
| Ramírez-Jarquín, UN; Tapia, R | 1 |
| Chen, L; Huang, M; Jiang, B; Li, S; Li, Y; Wang, L; Wang, X; Yang, Y; Zhang, X | 1 |
| Chuang, AY; Chuang, HH; Huang, CS; Lai, YC; Wang, GH; Yang, YC; Yeh, JY | 1 |
| Chan, MH; Chang, WT; Chen, HH; Kuo, TH; Sung, CW | 1 |
| Wang, C; Wang, G; Xie, K; Yu, Y; Yuan, Y; Zhou, Y | 1 |
2 review(s) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and 6-cyano-7-nitroquinoxaline-2,3-dione
| Article | Year |
|---|---|
The pharmacology of AMPA receptors and their antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Quinoxalines; Receptors, AMPA | 1993 |
Role of the amygdala, hippocampus and entorhinal cortex in memory consolidation and expression.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cerebral Cortex; Hippocampus; Memory; Muscimol; Quinoxalines; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate | 1993 |
298 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and 6-cyano-7-nitroquinoxaline-2,3-dione
| Article | Year |
|---|---|
Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Neurotransmitter; Recombinant Proteins; Xenopus laevis | 1992 |
Learning of a hippocampal-dependent conditioning task changes the binding properties of AMPA receptors in rabbit hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Mapping; Conditioning, Classical; Conditioning, Eyelid; Hippocampus; Ibotenic Acid; Male; Phencyclidine; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1992 |
Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Phenols; Polyamines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1992 |
Suppression of a calcium current by CNQX and kynurenate.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anticonvulsants; Calcium Channel Blockers; Cells, Cultured; Electrophysiology; Excitatory Amino Acid Antagonists; Ibotenic Acid; Ictaluridae; Kynurenic Acid; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Retina | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Fast excitatory postsynaptic potentials and the responses to excitant amino acids of sympathetic preganglionic neurons in the slice of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1992 |
CNQX binding to non-NMDA glutamate receptors in canine cerebro-cortical crude synaptosomal membranes: pharmacological characterization and comparison of binding parameters in dogs with congenital portosystemic encephalopathy and control dogs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Dogs; Female; Hepatic Encephalopathy; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; Male; Membranes; Quinoxalines; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Increasing binding affinity of agonists to glutamate receptors increases synaptic responses at glutamatergic synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Azides; Binding, Competitive; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Perchlorates; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium Azide; Sodium Compounds; Synapses; Telencephalon; Thiocyanates | 1992 |
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Brain; Brain Injuries; Diazepam; Dizocilpine Maleate; Female; Ibotenic Acid; Male; N-Methylaspartate; Neurotoxins; Organ Specificity; Phenytoin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Seizures | 1992 |
Evoked endogenous taurine release from cultured cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Taurine | 1992 |
Developmental changes in the effects of drugs acting at NMDA or non-NMDA receptors on synaptic transmission in the chick cochlear nucleus (nuc. magnocellularis).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Chick Embryo; Cochlear Nerve; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Embryonic and Fetal Development; Evoked Potentials; Ibotenic Acid; N-Methylaspartate; Piperazines; Quinolinic Acid; Quinolinic Acids; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Phospholipase A2-induced changes in AMPA receptor: an autoradiographic study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ibotenic Acid; Male; Oxadiazoles; Phospholipases A; Phospholipases A2; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Neurotransmitter; Tritium | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Exocytosis; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Taurine | 1991 |
Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cerebellum; Gene Expression; Hippocampus; Ibotenic Acid; Neurons; Nucleic Acid Hybridization; Oligonucleotide Probes; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; RNA Splicing; RNA, Messenger | 1991 |
Differential intracellular calcium responses to glutamate in type 1 and type 2 cultured brain astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Brain; Calcium; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Glial Fibrillary Acidic Protein; Glutamates; Ibotenic Acid; Immunohistochemistry; Kainic Acid; Potassium; Quinoxalines; Rats; Rats, Inbred Strains | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic modulation of glutamate and dynorphin release by excitatory amino acids in the guinea-pig hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dynorphins; Glutamates; Guinea Pigs; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Potassium; Quinoxalines; Quisqualic Acid; Synapses; Synaptosomes | 1991 |
GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediated.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Cerebellum; Chlorides; Cyclic GMP; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kynurenic Acid; Lithium; Lithium Chloride; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nipecotic Acids; Nitroprusside; Organic Anion Transporters; Proline; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Secretory Rate; Sodium; Stimulation, Chemical | 1991 |
Developmental changes in the susceptibility to long-term potentiation of neurones in rat visual cortex slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Visual Cortex | 1991 |
Cerebellar excitatory amino acid binding sites in normal, granuloprival, and Purkinje cell-deficient mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellar Cortex; Dendrites; Denervation; Ibotenic Acid; Methylazoxymethanol Acetate; Mice; Mice, Neurologic Mutants; Purkinje Cells; Quinoxalines; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1991 |
Excitatory amino acid receptors mediate synaptic responses to visual stimuli in superior colliculus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Neurons; Photic Stimulation; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1991 |
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Embryo, Mammalian; Evoked Potentials; Hippocampus; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pyramidal Tracts; Pyrrolidinones; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1991 |
Differential regulation of cerebellar granule neurons by two types of quisqualate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cerebellar Cortex; Cycloleucine; Diltiazem; Glutaminase; Ibotenic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Neuronal Plasticity; Neurons; Nifedipine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Capsaicin; Functional Laterality; Hot Temperature; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neuronal Plasticity; Neuropeptides; Pain; Quinoxalines; Rats; Reflex; Time Factors | 1991 |
Primary afferents evoke excitatory amino acid receptor-mediated EPSPs that are modulated by presynaptic GABAB receptors in lamprey.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Ibotenic Acid; Interneurons; Kynurenic Acid; Lampreys; Mechanoreceptors; N-Methylaspartate; Quinoxalines; Receptors, GABA-A; Receptors, Neurotransmitter; Skin; Spinal Cord; Synapses; Synaptic Transmission | 1991 |
Reduction of desensitization of a glutamate ionotropic receptor by antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channels; Membrane Potentials; Oocytes; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1991 |
Desensitization and resensitization rates of glutamate-activated channels may regulate motoneuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Chick Embryo; Electrophysiology; Glutamates; Ibotenic Acid; Ion Channels; Kainic Acid; Motor Neurons; Quinoxalines; Quisqualic Acid; Synaptic Transmission | 1991 |
Potentiation of a behavioural response in mice by spinal coadministration of substance P and excitatory amino acid agonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Analgesics; Animals; Behavior, Animal; Drug Synergism; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nociceptors; Piperazines; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Substance P | 1991 |
Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Oxadiazoles; Oxazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Modulation of non-N-methyl-D-aspartate receptors in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Cyclic GMP; Granulocytes; Ibotenic Acid; Kainic Acid; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Glutamate receptors activate Ca2+ mobilization and Ca2+ influx into astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Benzofurans; Brain; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Fluorescent Dyes; Fura-2; Glutamates; Hippocampus; Ibotenic Acid; Nickel; Nimodipine; Organ Specificity; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
(2S,3S,4S) alpha-(carboxycyclopropyl)glycine is a novel agonist of metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Electric Stimulation; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Kainic Acid; N-Methylaspartate; Piperazines; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred F344; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptosomes | 1990 |
Homomeric GluR1 excitatory amino acid receptors expressed in Xenopus oocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Ganglia, Spinal; Hippocampus; Ibotenic Acid; Kainic Acid; Membrane Proteins; Oocytes; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1990 |
Autoradiographic distribution of binding sites for the non-NMDA receptor antagonist CNQX in chick brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Chickens; Ibotenic Acid; Organ Specificity; Quinoxalines; Tritium | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ibotenic Acid; Kainic Acid; Magnesium; Membrane Potentials; Neurons; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
On concanavalin A-treated striatal neurons quisqualate clearly behaves as a partial agonist of a receptor fully activated by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Concanavalin A; Corpus Striatum; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Mice; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Veratridine | 1990 |
Augmentation by glycine and blockade by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) of responses to excitatory amino acids in slices of rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cerebral Cortex; Drug Interactions; Electrophysiology; Female; Glycine; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Somatosensory Cortex | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid; Quinoxalines; Rats; Synapses | 1989 |
6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Female; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Synapses | 1989 |
Non-NMDA glutamate receptor antagonist 3H-CNOX binds with equal affinity to two agonist states of quisqualate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Glutamates; Ibotenic Acid; In Vitro Techniques; Molecular Weight; Oxadiazoles; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Temperature | 1989 |
Two pharmacological classes of quisqualate-induced electrical responses in rat retinal ganglion cells in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Neuromuscular Depolarizing Agents; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Retina; Retinal Ganglion Cells | 1989 |
Excitation of hippocampal neurons by stimulation of glutamate Qp receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electric Stimulation; Electrophysiology; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neurons; Oxadiazoles; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Muscarinic; Receptors, Neurotransmitter | 1989 |
Evidence for a single glutamate receptor of the ionotropic kainate/quisqualate type.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Protein Conformation; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; Xenopus laevis | 1989 |
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Cell Membrane; Cerebral Cortex; Ibotenic Acid; Kainic Acid; Ketamine; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors modulate dopamine release in rat hippocampus and striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Diazoxide; Dopamine; Dose-Response Relationship, Drug; Hippocampus; Male; Rats; Rats, Wistar; Receptors, AMPA; Time Factors | 1995 |
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspiration.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Apnea; Blood Pressure; Cats; Female; Heart Rate; Male; Microinjections; N-Methylaspartate; Piperazines; Pulmonary Ventilation; Receptors, N-Methyl-D-Aspartate; Respiration; Solitary Nucleus; Vagotomy | 1995 |
Activation of metabotropic glutamate receptors induces an inward current in rat dopamine mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Dopamine; Electrophysiology; Female; Glycine; Male; Neurons; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stimulation, Chemical; Tetrodotoxin | 1993 |
Functional kainate-selective glutamate receptors in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Embryo, Mammalian; Hippocampus; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Pharmacological evidence for involvement of excitatory amino acids in aversive responses induced by intrathecal substance P in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Biphenyl Compounds; Injections, Spinal; Kainic Acid; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Neurokinin-1; Substance P | 1993 |
Simultaneous local pressure microejection of excitatory amino acids and field potential recording with a single micropipette in the hippocampal slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Electrophysiology; Hippocampus; In Vitro Techniques; Injections, Jet; Iontophoresis; Microinjections; N-Methylaspartate; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin | 1993 |
Enhancement of AMPA-mediated synaptic transmission by the protein phosphatase inhibitor calyculin A in rat hippocampal slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Hippocampus; In Vitro Techniques; Isoquinolines; Long-Term Potentiation; Magnesium; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Piperazines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Synaptic Transmission | 1993 |
Multivesicular release from excitatory synapses of cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Electric Stimulation; Evoked Potentials; Hippocampus; N-Methylaspartate; Neurons; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1994 |
Activation of alpha-adrenoceptors indirectly facilitates sodium pumping in frog motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Clonidine; Motor Neurons; N-Methylaspartate; Norepinephrine; Prazosin; Propranolol; Quinoxalines; Rana pipiens; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tetrodotoxin | 1993 |
Evidence that GYKI 52466, a novel non-NMDA antagonist enhances the decay of kainate-induced current in cultured chicken cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Quinoxalines | 1994 |
A comparison of non-NMDA receptor channels in type-2 astrocytes and granule cells from rat cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Cerebellum; Concanavalin A; Cytoplasmic Granules; Electrophysiology; In Vitro Techniques; Ion Channels; Kainic Acid; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1994 |
Expression of non-NMDA glutamate receptor channel genes by clonal human neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Base Sequence; Blotting, Southern; Cell Differentiation; Clone Cells; DNA Primers; Gene Expression; Humans; Ion Channels; Kainic Acid; L-Lactate Dehydrogenase; Molecular Sequence Data; Neurons; Polymerase Chain Reaction; Quinoxalines; Receptors, Glutamate; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured | 1994 |
Glutamatergic control of dopamine release during stress in the rat prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Pain; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 1994 |
The effect of experimental ischaemia and excitatory amino acid agonists on the GABA and serotonin immunoreactivities in the rabbit retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cycloleucine; Dextromethorphan; Eye Proteins; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Intraocular Pressure; Ischemia; Kainic Acid; Kynurenic Acid; Memantine; N-Methylaspartate; Oxygen; Potassium Cyanide; Quinoxalines; Rabbits; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Vessels; Serotonin | 1994 |
Kainate binding to the AMPA receptor in rat brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain; Cell Membrane; Cytosol; Kainic Acid; Kinetics; Male; Protein Binding; Quinoxalines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1994 |
The effects of L-glutamate, AMPA, quisqualate, and kainate on retinal horizontal cells depend on adaptational state: implications for rod-cone interactions.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adaptation, Physiological; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dopamine; Electric Conductivity; Excitatory Amino Acid Antagonists; Glutamates; Kainic Acid; Light; Male; Quinoxalines; Quisqualic Acid; Retina; Retinal Rod Photoreceptor Cells; Xenopus laevis | 1994 |
CNQX infused into entorhinal cortex blocks memory expression, and AMPA reverses the effect.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Exploratory Behavior; Hippocampus; Injections; Memory; Motor Activity; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA | 1994 |
Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cold Temperature; Cytosol; Dizocilpine Maleate; Fetus; Glucose; Glutamic Acid; Glycine; Hypothermia, Induced; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurons | 1994 |
A novel photoaffinity ligand for kainate sites labels two polypeptides with molecular mass 45 and 33.5 kDa in chick cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Affinity Labels; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Azides; Binding, Competitive; Cell Membrane; Cerebellum; Chickens; Electrophoresis, Polyacrylamide Gel; Kainic Acid; Kinetics; Molecular Weight; Peptides | 1994 |
Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Membrane; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Isoxazoles; Male; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Structure-Activity Relationship | 1994 |
AMPA/Zn(2+)-induced neurotoxicity in rat primary cortical cultures: involvement of L-type calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cell Death; Cells, Cultured; Cerebral Cortex; Chlorides; Diltiazem; Edetic Acid; Egtazic Acid; Female; Fetus; Kinetics; Membrane Potentials; Neurons; Neurotoxins; Pregnancy; Rats; Rats, Wistar; Synaptic Transmission; Time Factors; Zinc Compounds | 1994 |
GABAergic activity of quisqualamine and homoquisqualamine in hemisected spinal cord in vitro preparation.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Bicuculline; Decarboxylation; Evoked Potentials; GABA Agonists; Magnesium; Muscimol; Picrotoxin; Quisqualic Acid; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1994 |
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ethanol; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Naloxone; Nucleus Accumbens; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission | 1994 |
Autoradiographic characterization of [3H]6-cyano-7-nitroquinoxaline-2,3-dione binding sites in adult chick brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Cerebellum; Chickens; Excitatory Amino Acid Agonists; Kainic Acid; Kinetics; Nerve Tissue Proteins; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1994 |
Glycine release from hippocampal slices in developing and ageing mice: modulation by glutamatergic receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dizocilpine Maleate; Female; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; N-Methylaspartate; Potassium; Quisqualic Acid; Receptors, Glutamate; Tetrazoles | 1994 |
Taurine release from mouse hippocampal slices: effects of glutamatergic substances and hypoxia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Mice; N-Methylaspartate; Nitrogen; Oxygen; Potassium; Quisqualic Acid; Taurine | 1994 |
Release of [3H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca2+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Chick Embryo; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; N-Methylaspartate; Nicotinic Acids; Nipecotic Acids; Oximes; Quisqualic Acid; Retina; Tritium | 1994 |
Tonic desensitization of hippocampal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors regulates 5-hydroxytryptamine release in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diazoxide; Extracellular Space; Hippocampus; Male; Microdialysis; Rats; Rats, Wistar; Receptors, AMPA; Serotonin | 1994 |
Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane Permeability; Dendrites; Electric Conductivity; Hippocampus; Kainic Acid; Magnesium; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors; Zinc | 1995 |
The importance of two specific domains in ligand binding to the AMPA/kainate glutamate receptors GluR2 and GluR6.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Blotting, Western; Calcium; Cell Line; Cricetinae; Gene Expression; Kainic Acid; Kidney; Quinoxalines; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Transfection; Tritium | 1995 |
Changes of extracellular calcium concentration induced by application of excitatory amino acids in the human neocortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Humans; In Vitro Techniques; Injections; Male; Membrane Potentials; N-Methylaspartate | 1995 |
A functionally active presynaptic high-affinity kainate receptor in the rat hippocampal CA3 subregion.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Hippocampus; Kainic Acid; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Synaptosomes | 1995 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
AMPA receptor activation regulates the glutamate metabotropic receptor stimulated phosphatidylinositol turnover in human cerebral cortex slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcimycin; Cerebral Cortex; Child; Cycloleucine; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Male; Middle Aged; N-Methylaspartate; Phosphatidylinositols; Quisqualic Acid; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrodotoxin | 1995 |
Phospholipase A2 down-regulates the affinity of [3H]AMPA binding to rat cortical membranes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Binding, Competitive; Calcium; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Membranes; Phospholipases A; Phospholipases A2; Protease Inhibitors; Rats; Rats, Wistar; Sulfhydryl Compounds; Temperature; Tritium | 1995 |
Effects of L-trans-pyrrolidine-2,4-dicarboxylate and L-threo-3-hydroxyaspartate on the binding of [3H]L-aspartate, [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), [3H]DL-(E)-2-amino-4-propyl-5-phosphono-3-pentenoate (CGP 39653), [3H]6-cya
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Kainic Acid; Neurotransmitter Uptake Inhibitors; Prosencephalon; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1995 |
Regulation of spontaneous phasic firing of rat supraoptic vasopressin neurones in vivo by glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electrophysiology; Kainic Acid; Male; N-Methylaspartate; Oxytocin; Rats; Receptors, Glutamate; Supraoptic Nucleus; Vasopressins | 1995 |
Characterization of the binding of [3H]NS 257, a novel competitive AMPA receptor antagonist, to rat brain membranes and brain sections.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Cell Membrane; Cerebral Cortex; Hydrogen-Ion Concentration; Indoles; Kainic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sulfonamides; Thiocyanates; Tritium | 1995 |
Independent mechanisms for long-term depression of AMPA and NMDA responses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Artifacts; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
Subcellular localization and molecular pharmacology of distinct populations of [3H]-AMPA binding sites in rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Cell Fractionation; Glutamic Acid; Hippocampus; In Vitro Techniques; Isotope Labeling; Kainic Acid; Microscopy, Electron; Microsomes; Neuronal Plasticity; Protein Processing, Post-Translational; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glutamate; Synaptosomes; Tritium | 1995 |
Developmental changes in alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor properties and expression in the rat hippocampal formation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Distribution; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Gene Expression; Hippocampus; In Situ Hybridization; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger | 1995 |
Pressor responses to stimulation of non-NMDA receptors in the superficial laminae of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Blood Pressure; Cats; Decerebrate State; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Microinjections; N-Methylaspartate; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Spinal Cord | 1995 |
Binding of the new radioligand (S)-[3H]AMPA to rat brain synaptic membranes: effects of a series of structural analogues of the non-NMDA receptor agonist willardiine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cycloleucine; Male; Pyrimidinones; Quinoxalines; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Stereoisomerism; Synaptic Membranes; Tritium; Uracil | 1995 |
Involvement of AMPA receptors in maintenance of memory for a passive avoidance task in day-old domestic chicks (Gallus domesticus).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Autoradiography; Avoidance Learning; Chickens; Densitometry; Female; Injections; Kinetics; Male; Memory; Prosencephalon; Receptors, AMPA | 1995 |
Actions of agonists of metabotropic glutamate receptors on synaptic transmission and transmitter release in the olfactory cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cycloleucine; Ibotenic Acid; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Olfactory Bulb; Potassium; Quinoxalines; Receptors, Glutamate; Synapses; Synaptic Transmission | 1993 |
Thiocyanate equally increases affinity for two DL-alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA) receptor states.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Thiocyanates | 1993 |
Glutamate dehydrogenase improves binding of [3H]CGP39653 to NMDA receptors in the autoradiographic assay.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
A novel mechanism of AMPA receptor regulation: ionically triggered kinases and phosphatases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Chlorides; Glycerophosphates; Ibotenic Acid; In Vitro Techniques; Isoquinolines; Peptides; Phosphoric Monoester Hydrolases; Piperazines; Potassium; Protein Kinase Inhibitors; Protein Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Sodium; Tamoxifen; Vanadates | 1993 |
Identification of glutamate receptor subtypes mediating inputs to bipolar cells and ganglion cells in the tiger salamander retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ambystoma; Aminobutyrates; Animals; Glutamates; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Photic Stimulation; Piperazines; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Synapses | 1993 |
Photostimulation using caged glutamate reveals functional circuitry in living brain slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cats; Evoked Potentials; Ferrets; Glutamates; Hippocampus; Ibotenic Acid; In Vitro Techniques; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Somatosensory Cortex; Synapses; Tetrodotoxin; Ultraviolet Rays; Visual Cortex | 1993 |
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glucagon; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Islets of Langerhans; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Ketamine; Male; Neurons; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Quinoxalines; Rana pipiens; Receptors, AMPA; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses; Tetrodotoxin; Thalamus | 1993 |
Gamma-D-glutamylaminomethyl sulfonic acid (GAMS) distinguishes kainic acid- from AMPA-induced responses in Xenopus oocytes expressing chick brain glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Chick Embryo; Electrophysiology; Glutamine; Kainic Acid; Kinetics; Oocytes; Quinoxalines; Receptors, Glutamate; RNA, Messenger; Xenopus | 1993 |
Intra-nigra infusion of AMPA attenuates dopamine-dependent rotation in the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Dopamine; Dopamine Agents; Dopamine Antagonists; Injections; Male; Motor Activity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Rotation; Stereotyped Behavior; Substantia Nigra; Thalamic Nuclei; Tyrosine 3-Monooxygenase | 1993 |
Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Cytosol; Enzyme Activation; Fetus; Molecular Sequence Data; Neurons; Oligopeptides; Phorbol 12,13-Dibutyrate; Picrotoxin; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substrate Specificity; Synapses | 1993 |
Stimulation of oxytocin release in the lactating rat by central excitatory amino acid mechanisms: evidence for specific involvement of R,S-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-sensitive glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium Channel Blockers; Female; Lactation; Oxytocin; Prolactin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Sodium Channel Blockers; Vasopressins | 1993 |
Stimulation of oxytocin release in the lactating rat by a central interaction of alpha 1-adrenergic and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-sensitive excitatory amino acid mechanisms.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Drug Synergism; Female; Lactation; Oxytocin; Phenylephrine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Supraoptic Nucleus | 1993 |
Transmitter release associated with long-term synaptic depression in rat corticostriatal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Dopamine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; In Vitro Techniques; Neostriatum; Neuronal Plasticity; Neurotransmitter Agents; Rats; Rats, Wistar; Synapses | 1995 |
On the mechanism of long-term potentiation induced by (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD) in rat hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channel Blockers; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Female; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Nimodipine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 1995 |
Preferential block of desensitizing AMPA receptor in hippocampal neurons by gamma-D-glutamylaminomethylsulfonic acid.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamine; Hippocampus; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Neurons; Rats; Rats, Wistar; Receptors, AMPA | 1995 |
The complementary nature of long-term depression and potentiation revealed by dual component excitatory postsynaptic potentials in hippocampal slices from young rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1995 |
Regulation of N-methyl-D-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apomorphine; Cyclopentanes; GABA Agonists; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Microscopy, Video; Motor Activity; N-Methylaspartate; Neostriatum; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reference Values | 1996 |
Glutamate receptor agonists modulate [Ca2+]i in isolated rat melanotropes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Fluorescent Dyes; Fura-2; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Male; N-Methylaspartate; Pituitary Gland; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 1995 |
Characterization of excitatory amino acid modulation of dopamine release in the prefrontal cortex of conscious rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Consciousness; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 1996 |
Septal and hippocampal glutamate receptors modulate the output of acetylcholine in hippocampus: a microdialysis study.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, Glutamate; Septal Nuclei | 1996 |
DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclopropanes; Glycine; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotoxins; Pertussis Toxin; Receptors, Metabotropic Glutamate; Virulence Factors, Bordetella | 1996 |
L-Glutamate-induced responses in OFF-type bipolar cells of the cat retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Aspartic Acid; Calcium; Cats; Chlorides; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; In Vitro Techniques; Ion Transport; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Potassium; Retina; Retinal Cone Photoreceptor Cells; Sodium | 1996 |
Cobalt-permeable non-NMDA receptors in developing chick brainstem auditory nuclei.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Benzodiazepines; Brain Stem; Cell Membrane Permeability; Chick Embryo; Cobalt; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Neurons; Receptors, N-Methyl-D-Aspartate | 1995 |
Release of vasopressin and oxytocin by excitatory amino acid agonists and the effect of antagonists on release by muscarine and hypertonic saline, in the rat in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Diuresis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Muscarine; Muscarinic Agonists; N-Methylaspartate; Oxytocin; Rats; Rats, Wistar; Saline Solution, Hypertonic; Urodynamics; Vasoconstrictor Agents; Vasopressins | 1996 |
Distribution of neurones expressing inwardly rectifying and Ca(2+)-permeable AMPA receptors in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Synaptic Transmission | 1996 |
Developmental changes in glutamate receptor-activated translocation of protein kinase C in cerebellar granule neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Biological Transport; Carcinogens; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurotoxins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tritium | 1996 |
Domoic acid induces the release of glutamate in the rat hippocampal CA3 subregion.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Synaptosomes | 1996 |
Effect of magnesium sulfate on excitatory amino acid receptors in the rat brain. II. Kainate and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Hippocampus; Injections, Intraperitoneal; Magnesium; Magnesium Sulfate; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Tritium | 1996 |
Microdialysis of a non-NMDA receptor antagonist into the L7 dorsal horn attenuates the pressor response to static muscle contraction but not passive stretch in cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Cats; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Heart Rate; Lidocaine; Lumbosacral Region; Microdialysis; Muscle Contraction; Muscle Spindles; N-Methylaspartate; Reflex; Spinal Cord | 1996 |
Excitatory responses evoked in prefrontal cortex by mediodorsal thalamic nucleus stimulation: influence of anaesthesia.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Anesthetics; Animals; Halothane; Ketamine; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thalamus | 1995 |
Electrophysiological characterization of non-NMDA glutamate receptors on cultured intermediate lobe cells of the rat pituitary.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Electric Conductivity; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Membrane Potentials; Pituitary Gland; Quisqualic Acid; Rats; Receptors, Glutamate | 1996 |
Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine Agents; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Postpartum Period; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 1996 |
Quantal release of transmitter at a central synapse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dendrites; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Neurons; Quantum Theory; Rats; Synapses | 1996 |
The ventral subiculum modulation of prepulse inhibition is not mediated via dopamine D2 or nucleus accumbens non-NMDA glutamate receptor activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1996 |
Chronic treatment with typical and atypical antipsychotics increases the AMPA-preferring form of AMPA receptor in rat brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Brain; Clozapine; Haloperidol; Male; Pimozide; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Risperidone; Tritium | 1996 |
Electrophysiological and pharmacological characteristics of ionotropic glutamate receptors in medial vestibular nucleus neurons: a whole cell patch clamp study in acutely dissociated neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Membrane Potentials; Microscopy, Polarization; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glutamate; Vestibular Nuclei | 1996 |
Cholecystokinin and neurotensin inversely modulate excitatory synaptic transmission in the parabrachial nucleus in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzodiazepinones; Cholecystokinin; Devazepide; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hormone Antagonists; Interneurons; N-Methylaspartate; Neural Inhibition; Neurons, Afferent; Neurotensin; Patch-Clamp Techniques; Phenylurea Compounds; Pons; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Receptors, Neurotensin; Synaptic Transmission; Tetrodotoxin | 1997 |
Effects of glutamate receptor agonists and antagonists on Ca2+ uptake in rat hippocampal slices lesioned by glucose deprivation or by kainate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glucose; Hippocampus; Kainic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1997 |
Experimental erbium laser surgery in the guinea pig cochlea: its use in the study of afferent cochlear neurotransmitters.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlea; Erbium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Laser Therapy; Male; Microelectrodes; N-Methylaspartate; Neurotransmitter Agents; Synaptic Transmission | 1996 |
Activation of AMPA and kainate glutamate receptors impairs the viability of oligodendrocytes in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Oligodendroglia; Optic Nerve; Protein Conformation; Rats; Receptors, AMPA; Receptors, Kainic Acid | 1996 |
Intracellular Ca2+, Na+ and H+ transients evoked by kainate in the leech giant glial cells in situ.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Electric Conductivity; Fura-2; Gallopamil; Ganglia, Invertebrate; Hydrogen-Ion Concentration; In Vitro Techniques; Kainic Acid; Kinetics; Leeches; Membrane Potentials; Microelectrodes; Neuroglia; Nickel; Patch-Clamp Techniques; Receptors, Glutamate; Sodium | 1997 |
Characterization of ionotropic glutamate receptor-mediated nitric oxide production in vivo in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrulline; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Glutamate-induced hyperpolarization in mouse cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Purkinje Cells; Quisqualic Acid | 1993 |
Glutamatergic enteric neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Benzothiadiazines; Calcium; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hexamethonium; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Microscopy, Immunoelectron; Muscle, Smooth; Myenteric Plexus; Neurons; Nicotine; Organelles; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles; Tetrodotoxin | 1997 |
NMDA receptor-mediated regulation of AMPA receptor properties in organotypic hippocampal slice cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calpain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Molecular Weight; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Tritium | 1997 |
Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cysteine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genes, fos; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; RNA, Messenger | 1997 |
Apoptosis induced via AMPA-selective glutamate receptors in cultured murine cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Apoptosis; Cells, Cultured; Cerebral Cortex; Chromatin; DNA Fragmentation; Electrophoresis, Agar Gel; Embryo, Mammalian; Embryo, Nonmammalian; Isoquinolines; Neurites; Neurons; Receptors, AMPA; Tetrazoles | 1997 |
Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Electric Stimulation; Endocytosis; Evoked Potentials; Ganglia, Spinal; Hyperalgesia; Long-Term Potentiation; Male; Microscopy, Confocal; Microscopy, Fluorescence; Models, Neurological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1997 |
Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Ferrets; gamma-Aminobutyric Acid; Indoles; Ligands; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tropisetron; Virulence Factors, Bordetella; Visual Cortex | 1997 |
Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Male; Picrotoxin; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin | 1997 |
Regional decreases in alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) and 6-[3H]cyano-7-nitroquinoxaline-2,3-dione ([3H]CNQX) binding in response to chronic low-level lead exposure: reversal versus potentiation by chronic dopamine
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Binding Sites; Brain; Dopamine Agonists; Lead; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Reference Values; Time Factors; Tissue Distribution; Tritium | 1997 |
Some behavioral effects of AMPA/kainate receptor agonist and antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Conflict, Psychological; Drinking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid | 1997 |
AMPA receptor-mediated slow neuronal death in the rat spinal cord induced by long-term blockade of glutamate transporters with THA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Cell Death; Glutamic Acid; Hindlimb; Infusions, Parenteral; Injections, Spinal; Male; Motor Activity; Neurons; Paralysis; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Subarachnoid Space; Tail; Time Factors; Urinary Incontinence | 1997 |
Concentration-dependent changes in motor behavior produced by continuous intrathecal infusion of excitatory amino acids in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Drug Combinations; Excitatory Amino Acid Agonists; Infusion Pumps; Injections, Spinal; Male; Motor Activity; Osmolar Concentration; Rats; Rats, Wistar; Spinal Cord | 1997 |
Glutamate is the transmitter for N2v retraction phase interneurons of the Lymnaea feeding system.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Interneurons; Lymnaea; Motor Neurons; Nerve Net; Quisqualic Acid; Synapses | 1997 |
Antipsychotic drug regulation of AMPA receptor affinity states and GluR1, GluR2 splice variant expression.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Antipsychotic Agents; Autoradiography; Binding, Competitive; Brain Chemistry; Clozapine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Haloperidol; In Situ Hybridization; Male; Pimozide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Risperidone; RNA, Messenger; Sodium Chloride; Tritium | 1998 |
N- and P/Q-type Ca2+ channels mediate transmitter release with a similar cooperativity at rat hippocampal autapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; Mathematics; Neurotransmitter Agents; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Presynaptic Terminals; Rats; Spider Venoms; Synaptic Transmission; Synaptic Vesicles | 1998 |
Mannose-specific lectins modulate ligand binding to AMPA-type glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Brain Chemistry; Concanavalin A; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Ion Channel Gating; Kinetics; Long-Term Potentiation; Mannose; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Tritium | 1998 |
AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antihypertensive Agents; Benzothiadiazines; Calcium; Calcium Channel Blockers; Cell Death; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Homeostasis; Humans; Kainic Acid; Membrane Potentials; Neurons; Neurotoxins; Nimodipine; Potassium; Receptors, AMPA; Sodium; Sodium-Calcium Exchanger; Spider Venoms | 1998 |
Variability of AMPA and NMDA receptor mediated responses in CA1 pyramidal cells of young rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses | 1998 |
Differential roles for NMDA and non-NMDA receptor subtypes in baroreceptor afferent integration in the nucleus of the solitary tract of the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons, Afferent; Phenylephrine; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Synapses; Vasoconstrictor Agents | 1998 |
Selective changes in AMPA receptors in rabbit cerebellum following classical conditioning of the eyelid-nictitating membrane response.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blinking; Cerebellum; Conditioning, Classical; Electric Stimulation; Electrodes, Implanted; Ligands; Male; Nictitating Membrane; Protein Binding; Rabbits; Receptors, AMPA; Synapses; Temperature; Tritium | 1998 |
Non-NMDA receptor antagonist-induced drinking in rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Cerebral Ventricles; Dizocilpine Maleate; Drinking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Losartan; Male; Quinoxalines; Rats; Rats, Sprague-Dawley | 1998 |
Regulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Trigeminal Nuclei | 1998 |
Role of excitatory amino acids in the ventral tegmental area for central actions of non-competitive NMDA-receptor antagonists and nicotine.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Male; Nicotine; Parkinson Disease; Rats; Receptors, N-Methyl-D-Aspartate; Tourette Syndrome; Ventral Tegmental Area | 1998 |
Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Neurons, Afferent; Pain; Rats; Receptors, Kainic Acid; Spinal Cord; Synaptic Transmission | 1999 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Culture Techniques; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Chromans; Cysteine Proteinase Inhibitors; Dizocilpine Maleate; Dopamine Agonists; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Free Radicals; Hypoglycemic Agents; Insulin; Kainic Acid; Lipid Peroxidation; Mice; Microscopy, Electron; Mitochondrial Swelling; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Oligopeptides; Oxidative Stress; Pregnancy; Zinc | 1999 |
Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Activation of excitatory amino acid receptors in bovine dental pulp evokes the release of iCGRP.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Cattle; Dental Pulp; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurogenic Inflammation; Neurons, Afferent; Nociceptors; Radioimmunoassay; Receptors, Glutamate; Statistics, Nonparametric | 1999 |
Actions of excitatory amino acids on mesencephalic trigeminal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acids; Kainic Acid; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Trigeminal Nuclei | 1998 |
Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dendrites; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; N-Methylaspartate; Pyramidal Cells; Rats | 1999 |
Mature hippocampal astrocytes exhibit functional metabotropic and ionotropic glutamate receptors in situ.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; omega-Conotoxins; Peptides; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; S100 Proteins; Tetrodotoxin | 1999 |
Molecular pathways mediating activation by kainate of mitogen-activated protein kinase in oligodendrocyte progenitors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Animals, Newborn; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavonoids; GTP-Binding Proteins; Indoles; Kainic Acid; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oligodendroglia; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Stem Cells; Tritium; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin | 1999 |
Enduring changes in Purkinje cell electrophysiology following transient exposure to AMPA: correlates to dark cell degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Sprague-Dawley; Reaction Time | 1999 |
Dopamine depresses glutamatergic synaptic transmission in the rat parabrachial nucleus in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Mianserin; Neurons; Patch-Clamp Techniques; Phentolamine; Pons; Quinpirole; Rats; Rats, Sprague-Dawley; Reaction Time; Sulpiride; Synaptic Transmission | 1999 |
Potentiation and depression following stimulus interruption in young rat hippocampi.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; N-Methylaspartate; Nifedipine; Rats; Rats, Sprague-Dawley; Reference Values | 1999 |
Ethanol modulates AMPA-induced current responses of primary somatosensory cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ethanol; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Glutamate; Somatosensory Cortex | 1999 |
Supralinear summation of synaptic inputs by an invertebrate neuron: dendritic gain is mediated by an "inward rectifier" K(+) current.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Calcium; Cobalt; Excitatory Postsynaptic Potentials; Ganglia, Invertebrate; In Vitro Techniques; Ion Channel Gating; Kinetics; Leeches; Membrane Potentials; Models, Neurological; Neurons; Patch-Clamp Techniques; Potassium Channels; Synapses; Synaptic Transmission | 1999 |
Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cerebellar Ataxia; Cerebellum; Evoked Potentials; In Vitro Techniques; Macromolecular Substances; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mice, Neurologic Mutants; Nerve Fibers; Neurons; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Nerve Growth Factor; Signal Transduction; Synapses; Synaptic Transmission; Transcription, Genetic | 1999 |
Entire course and distinct phases of day-lasting depression of miniature EPSC amplitudes in cultured Purkinje neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Evoked Potentials; Fetus; Kinetics; Neuroprotective Agents; Patch-Clamp Techniques; Potassium; Purkinje Cells; Rats; Rats, Wistar; Reaction Time | 1999 |
Glutamatergic receptors regulate expression, phosphorylation and accumulation of neurofilaments in spinal cord neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic Lateral Sclerosis; Animals; Anti-Anxiety Agents; Apoptosis; Benzodiazepines; Calcium Channels; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Humans; Meninges; Motor Neurons; Neurofilament Proteins; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Metabotropic glutamate receptors group I are involved in cochlear neurotransmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Indans; Methoxyhydroxyphenylglycol; N-Methylaspartate; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Non-NMDA receptors mediate both pressor and depressor actions of the cardiovascular-reactive areas in the brainstem of cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Pressure; Brain Stem; Cardiovascular Physiological Phenomena; Cats; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Medulla Oblongata; Receptors, Glutamate; Tegmentum Mesencephali | 1999 |
Regulation of substantia nigra pars reticulata neuronal activity by excitatory amino acids.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Iontophoresis; Kainic Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Substantia Nigra | 1999 |
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antioxidants; Calcium; Cells, Cultured; Cyclic N-Oxides; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Free Radicals; Glutamic Acid; Homeostasis; Humans; Imidazoles; Lipid Peroxidation; Mice; Mice, Transgenic; Mitochondria; Motor Neuron Disease; Motor Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Oxidative Stress; Rhodamine 123; Spinal Cord; Superoxide Dismutase; Superoxides; Vitamin E | 1999 |
Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channel Blockers; Cycloleucine; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Lumbosacral Region; Motor Neurons; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Spider Venoms; Spinal Cord | 2000 |
Kainate receptors activate NF-kappaB via MAP kinase in striatal neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcimycin; Calcium; Cells, Cultured; Corpus Striatum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; Immunohistochemistry; In Vitro Techniques; Ionophores; Kainic Acid; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; NF-kappa B; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Transcription Factor RelA | 2000 |
Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Chlorides; Cycloleucine; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Isoquinolines; Kainic Acid; Neurons; Picrotoxin; Retina; Strychnine; Zebrafish | 2000 |
Neurotrophin 3 potentiates glutamatergic responses of IHC afferents in the cochlea in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Carbazoles; Cochlea; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hair Cells, Auditory, Inner; In Vitro Techniques; Indole Alkaloids; Male; N-Methylaspartate; Nerve Fibers; Neurotrophin 3; Receptor, trkB; Receptor, trkC; Synapses | 2000 |
NMDA-induced changes in a cortical network in vivo are prevented by AMPA.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antihypertensive Agents; Benzothiadiazines; Cerebral Cortex; Evoked Potentials, Somatosensory; Male; N-Methylaspartate; Nerve Net; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2000 |
Pharmacological and molecular characterization of glutamate receptors in the MIN6 pancreatic beta-cell line.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Benzodiazepines; Benzothiadiazines; Biological Transport; Calcium; Cell Survival; DNA Primers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Islets of Langerhans; Kainic Acid; Protein Kinase C; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spider Venoms; Tumor Cells, Cultured | 2000 |
Stable expression of human homomeric and heteromeric AMPA receptor subunits in HEK293 cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Binding, Competitive; Blotting, Western; Cell Line; Electrophysiology; Glutamic Acid; Humans; Indoles; Kidney; Kinetics; Protein Subunits; Radioligand Assay; Receptors, AMPA; Sulfonamides; Transfection; Transformation, Genetic | 2000 |
In situ Ca2+ imaging reveals neurotransmitter receptors for glutamate in taste receptor cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Dextrans; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; Microscopy, Confocal; N-Methylaspartate; Neurotransmitter Agents; Organic Chemicals; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Taste Buds | 2000 |
Ionotropic glutamate receptors expressed in human retinoblastoma Y79 cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Blotting, Northern; Calcium; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gene Expression; Humans; Intracellular Fluid; Kainic Acid; N-Methylaspartate; Photoreceptor Cells, Vertebrate; Receptors, Glutamate; Retinoblastoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2000 |
A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Benzothiadiazines; Biological Transport; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Kinetics; Mice; Models, Theoretical; N-Methylaspartate; Sodium; Symporters | 2000 |
The lethal expression of the GluR2flip/GluR4flip AMPA receptor in HEK293 cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cell Death; Cell Line; Cell Survival; Evoked Potentials; Excitatory Amino Acid Antagonists; Humans; Kinetics; Membrane Potentials; Receptors, AMPA; Recombinant Proteins; Sodium; Transfection | 2000 |
Activation of ionotropic glutamate receptors reduces the production of transforming growth factor-beta2 by developing neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Wistar; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta | 2000 |
Altered pattern of light transmittance and resistance to AMPA-induced swelling in the dentate gyrus of the epileptic hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Edema; Dentate Gyrus; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Light; Male; Membrane Potentials; Neurons; Optics and Photonics; Organ Culture Techniques; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tetrodotoxin | 2000 |
Role of non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophysial explants.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Glutamates; Hypothalamo-Hypophyseal System; Kainic Acid; Kinetics; Male; N-Methylaspartate; Organ Culture Techniques; Oxytocin; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 2001 |
N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.
Topics: 2,4-Dinitrophenol; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cyclosporine; Dibucaine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Glutamic Acid; Heterocyclic Compounds, 3-Ring; Imidazoles; Kainic Acid; Mitochondria; Motor Neuron Disease; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rhodamines; Spinal Cord; Superoxide Dismutase; Uncoupling Agents | 2001 |
Expression and regulation of Na pump isoforms in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Cerebellum; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Kainic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Potassium Radioisotopes; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2001 |
Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and PI3 kinase.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Androstadienes; Animals; Corpus Striatum; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Wortmannin | 2001 |
Biphasic modulation of NMDA-induced responses in pyramidal cells of the medial prefrontal cortex by Y-931, a potential atypical antipsychotic drug.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Phencyclidine; Piperazines; Prefrontal Cortex; Pyramidal Cells; Rats | 2001 |
Glutamate, NMDA, and AMPA induced changes in extracellular space volume and tortuosity in the rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Chelating Agents; Diffusion; Dizocilpine Maleate; Edema; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Gliosis; Glutamic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; N-Methylaspartate; Potassium; Rats; Rats, Wistar; Spinal Cord | 2001 |
NMDA antagonists in the superior colliculus prevent developmental plasticity but not visual transmission or map compression.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain Mapping; Cricetinae; Electrophysiologic Techniques, Cardiac; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Mesocricetus; N-Methylaspartate; Neuronal Plasticity; Photic Stimulation; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Visual Fields; Visual Pathways; Visual Perception | 2001 |
The glutamate receptor agonist, AMPA, induces acetylcholine release in guinea pig cochlea; a microdialysis study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cholinesterase Inhibitors; Cochlea; Cochlear Nerve; Efferent Pathways; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Male; Microdialysis; Perfusion; Perilymph; Physostigmine; Presynaptic Terminals; Receptors, Glutamate | 2001 |
Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Blood Proteins; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Vectors; Glutamic Acid; Glycine; Green Fluorescent Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred ICR; Neuroprotective Agents; Patch-Clamp Techniques; Phosphoproteins; Purkinje Cells; Receptors, AMPA; Receptors, Metabotropic Glutamate; Sindbis Virus | 2001 |
Distinct NMDA and AMPA receptor-mediated responses in mouse and human Cajal-Retzius cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; In Vitro Techniques; Mice; Neurons; Piperidines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2001 |
Signaling pathways activated by chemokine receptor CXCR2 and AMPA-type glutamate receptors and involvement in granule cells survival.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cerebellum; Chemokines, CXC; Chemotactic Factors; Enzyme Activation; Growth Substances; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Interleukin-8B; Signal Transduction | 2002 |
Induction and blockade of epileptic foci by intracerebral injection of glutamatergic agonists and antagonists in frerly moving cats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Cats; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Microinjections; N-Methylaspartate; Neuroprotective Agents; Seizures | 2002 |
Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Lanthanum; Neurotoxins; Nifedipine; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 2002 |
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Calcium; Cells, Cultured; Cerebral Cortex; Cobalt; Diazoxide; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescence; Fluorometry; Fura-2; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2002 |
Ionotropic glutamate receptors mediate juvenile hormone synthesis in the cockroach, Diploptera punctata.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cockroaches; Corpora Allata; Cycloleucine; Cytosol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Juvenile Hormones; Kainic Acid; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Receptors, Metabotropic Glutamate | 2002 |
Excitatory mechanisms in the suprachiasmatic nucleus: the role of AMPA/KA glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Circadian Rhythm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Immunohistochemistry; Membrane Potentials; Microscopy, Video; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Suprachiasmatic Nucleus; Synaptic Transmission | 2002 |
Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Humans; Male; Membrane Potentials; Oocytes; Receptors, Neurotransmitter; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Temporal Lobe; Xenopus | 2002 |
Corticospinal transmission to motoneurons in cervical spinal cord slices from adult rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Axons; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Iontophoresis; Male; Motor Neurons; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Wistar; Spinal Cord; Synaptic Transmission | 2002 |
Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Culture Techniques; Cell Differentiation; Cell Survival; Ciliary Neurotrophic Factor; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fibroblast Growth Factors; Immunoblotting; Immunohistochemistry; Kainic Acid; Myelin Basic Protein; Oligodendroglia; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2003 |
A neural basis for auditory feedback control of vocal pitch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Brain Mapping; Chiroptera; Doppler Effect; Echolocation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Agonists; GABA Antagonists; Mesencephalon; Pitch Perception; Rhombencephalon; Vocalization, Animal | 2003 |
Involvement of N-methyl-D-aspartate receptors in post-hypoxic depression of the dorsomedial medulla in cats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spinal Nerves | 2003 |
RNA synthesis-dependent potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated toxicity by antihistamine terfenadine in cultured rat cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Aniline Compounds; Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Dactinomycin; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Histamine; Histamine H1 Antagonists; Kainic Acid; Neurons; Protein Synthesis Inhibitors; Rats; Receptors, AMPA; RNA; Terfenadine; Xanthenes | 2003 |
Decreased dendrite growth from cultured mouse cortical neurons surviving excitotoxic activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate/kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebral Cortex; Dendrites; Drug Interactions; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neurofilament Proteins; Neurons; Time Factors | 2003 |
Tumor necrosis factor alpha increases cytosolic calcium responses to AMPA and KCl in primary cultures of rat hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Agatoxins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Fura-2; Hippocampus; Mice; Neurons; omega-Conotoxin GVIA; Peptide Fragments; Potassium Chloride; Protein Synthesis Inhibitors; Rats; Receptors, Tumor Necrosis Factor; Spider Venoms; Tumor Necrosis Factor-alpha | 2003 |
Dual roles in feeding for AMPA/kainate receptors: receptor activation or inactivation within distinct hypothalamic regions elicits feeding behavior.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Glutamic Acid; Hypothalamic Area, Lateral; Hypothalamus; Male; Neural Pathways; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Synaptic Transmission | 2003 |
Dynamics of Ca(2+) and Na(+) in the dendrites of mouse cerebellar Purkinje cells evoked by parallel fibre stimulation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Boron Compounds; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Fluorescent Dyes; Glutamic Acid; Glycine; In Vitro Techniques; Iontophoresis; Male; Mice; omega-Conotoxin GVIA; Patch-Clamp Techniques; Purkinje Cells; Ryanodine; Sodium; Stimulation, Chemical; Tetrodotoxin; Time Factors | 2003 |
Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cell Line; Cells, Cultured; Cerebral Cortex; Endocytosis; Glutamic Acid; Humans; Neuronal Plasticity; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Synapses; Xenopus laevis | 2004 |
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors mediate development, but not maintenance, of secondary allodynia evoked by first-degree burn in the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Burns; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Injections, Spinal; Kainic Acid; Motor Cortex; Pain; Pain Threshold; Rats; Receptors, AMPA; Receptors, Kainic Acid; Spider Venoms | 2004 |
Afferent synaptic transmission in a hair cell organ: pharmacological and physiological analysis of the role of the extended refractory period.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hair Cells, Auditory; In Vitro Techniques; Nervous System Physiological Phenomena; Neurons, Afferent; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Refractory Period, Electrophysiological; Synapses; Synaptic Transmission; Tetraethylammonium; Xenopus laevis | 2004 |
Modulation of AMPA currents by D2 dopamine receptors in striatal medium-sized spiny neurons: are dendrites necessary?
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Calcium; Cells, Cultured; Corpus Striatum; Dendrites; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2004 |
NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Irreversible loss of a subpopulation of cortical interneurons in the absence of glutamatergic network activity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Bicuculline; Calbindin 2; Calcium; Calcium-Binding Proteins; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Nerve Net; Parvalbumins; Picrotoxin; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Time Factors; Valine | 2004 |
Hippocampal glutamate receptors in fear memory consolidation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Binding Sites; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Conditioning, Operant; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fear; Hippocampus; Inhibition, Psychological; Male; Memory; Phosphorylation; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Time Factors; Tritium | 2004 |
Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Northern; Body Weight; Chronic Disease; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression; Hypothalamus; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neurons; Organ Size; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Time Factors | 2004 |
Peripheral vestibular disorder induced by (+/-)-alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caloric Tests; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guinea Pigs; Male; Nystagmus, Pathologic; Vestibular Diseases | 2004 |
Glutamate mediates acute glucose transport inhibition in hippocampal neurons.
Topics: 4-Chloro-7-nitrobenzofurazan; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Biological Transport; Calcium Channels; Cells, Cultured; Deoxyglucose; Fluorescent Dyes; Glucosamine; Glucose; Glutamic Acid; Hippocampus; Monosaccharide Transport Proteins; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Channels | 2004 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cell Size; Circadian Rhythm; Cytochalasin D; Cytoskeleton; Dicarboxylic Acids; Dopamine; Eye Proteins; Glutamic Acid; Guinea Pigs; Ischemia; Kainic Acid; N-Methylaspartate; Neuroglia; Neurons; Nocodazole; Potassium; Pyrrolidines; Receptors, AMPA; Receptors, Kainic Acid; Retina; Retinal Ganglion Cells; Synaptic Transmission; Xanthenes | 2004 |
Electrophysiological and neurochemical characterization of neurons of the medial preoptic area in Japanese quail (Coturnix japonica).
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Coturnix; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Isonicotinic Acids; Kainic Acid; Male; N-Methylaspartate; Neurons; Norepinephrine; Preoptic Area; Pyridazines; Sympathomimetics | 2004 |
BDNF-induced facilitation of afferent-evoked responses in lamina II neurons is reduced after neonatal spinal cord contusion injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamin Type B; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Synaptic Transmission; Valine | 2005 |
Long-term potentiation of silent synapses in substantia gelatinosa neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Chelating Agents; Dose-Response Relationship, Radiation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Long-Term Potentiation; Magnesium; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synapses | 2005 |
Endogenous release and multiple actions of secretin in the rat cerebellum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium Channels; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Patch-Clamp Techniques; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Secretin | 2005 |
Depressor responses to L-proline microinjected into the rat ventrolateral medulla are mediated by ionotropic excitatory amino acid receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Proline; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 2005 |
Physiological role for casein kinase 1 in glutamatergic synaptic transmission.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Casein Kinase 1 epsilon; Casein Kinase I; Casein Kinase Ialpha; Casein Kinase Idelta; Corpus Striatum; Egtazic Acid; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neocortex; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 2005 |
Glutamate receptor-mediated effects on growth and morphology of human histiocytic lymphoma cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Proliferation; Cell Shape; Culture Media, Serum-Free; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Humans; Kainic Acid; Lymphoma, Large B-Cell, Diffuse; Microscopy, Electron; Receptors, Glutamate; Time Factors; U937 Cells | 2005 |
Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Inhalation; Animals; Cell Survival; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Male; N-Methylaspartate; Pertussis Toxin; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2005 |
Electrophysiological properties of human hypothalamic hamartomas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Bicuculline; Cadmium Chloride; Child; Child, Preschool; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Glutamic Acid; Hamartoma; Humans; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Infant; Isoenzymes; Kainic Acid; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periodicity; Phosphopyruvate Hydratase; Potassium Channel Blockers; Tetraethylammonium; Tetrodotoxin; Valine | 2005 |
Mitochondrial superoxide production and MnSOD activity after exposure to agonist and antagonists of ionotropic glutamate receptors in hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Injections; Kainic Acid; Mitochondria; N-Methylaspartate; Rats; Receptors, Kainic Acid; Superoxide Dismutase; Superoxides; Time Factors | 2005 |
Rapid control of brain aromatase activity by glutamatergic inputs.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aromatase; Brain; Coturnix; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate | 2006 |
Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cadmium Chloride; Calcium; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Subunits; Receptors, Kainic Acid; Substantia Gelatinosa | 2005 |
Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Allosteric Site; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Membranes; Peptides, Cyclic; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tritium | 2006 |
Synapse elimination in the corticospinal projection during the early postnatal period.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Axons; Behavior, Animal; Dextrans; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; Microscopy, Confocal; Presynaptic Terminals; Pyramidal Cells; Pyramidal Tracts; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Time Factors | 2006 |
Spontaneous network activity in the embryonic spinal cord regulates AMPAergic and GABAergic synaptic strength.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Bicuculline; Chick Embryo; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Lidocaine; Membrane Potentials; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Reaction Time; Spinal Cord; Synapses; Synaptic Transmission | 2006 |
Properties of the new fluorescent Na+ indicator CoroNa Green: comparison with SBFI and confocal Na+ imaging.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzofurans; Calibration; Ethers, Cyclic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Hippocampus; In Vitro Techniques; Indicators and Reagents; Membrane Potentials; Mice; Microscopy, Confocal; Neurons; Patch-Clamp Techniques; Potassium; Sodium | 2006 |
Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Crystallography, X-Ray; Excitatory Amino Acid Antagonists; GluK2 Kainate Receptor; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Quinoxalines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Thymine; Xenopus laevis | 2006 |
New role for spinal Stargazin in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated pain sensitization after inflammation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Calcium Channels; Disease Models, Animal; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation; Immunoprecipitation; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Motor Activity; Oligonucleotides, Antisense; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord | 2006 |
Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Administration, Oral; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Behavior, Animal; Cell Hypoxia; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fructose; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Maze Learning; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Topiramate | 2006 |
In vitro galantamine-memantine co-application: mechanism of beneficial action.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Animals; Bicuculline; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Drug Evaluation, Preclinical; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Galantamine; Glycine; In Vitro Techniques; Inhibitory Concentration 50; Memantine; Nerve Tissue Proteins; Neuroprotective Agents; Nicotinic Agonists; Patch-Clamp Techniques; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Strychnine; Synaptic Transmission; Therapeutic Irrigation | 2006 |
Molecular mechanisms of neurite growth with AMPA receptor potentiation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Humans; Neurites; Neuroblastoma; Neurofilament Proteins; Receptor, trkA; Receptors, AMPA; Sulfonamides | 2007 |
AMPA receptor activation reduces epileptiform activity in the rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Benzothiadiazines; Bicuculline; Chlormethiazole; Diazepam; Electroencephalography; Epilepsy; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Neocortex; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2007 |
Effects of 17beta-estradiol on neuronal cell excitability and neurotransmission in the suprachiasmatic nucleus of rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fulvestrant; GABA Antagonists; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus | 2008 |
Dopaminergic modulation of spinal neuronal excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Dopamine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Reaction Time; Serotonin; Spinal Cord; Stilbamidines | 2007 |
Presynaptic modulation by somatostatin in the neostriatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Somatostatin; Valine | 2008 |
Glutamate mediates platelet activation through the AMPA receptor.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Platelets; Glutamic Acid; Humans; In Vitro Techniques; Ion Transport; Kainic Acid; Male; Membrane Potentials; Mice; Mice, Knockout; Platelet Activation; Receptors, AMPA; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium; Thrombosis | 2008 |
NMDA and GABA B receptors are involved in controlling nematocyst discharge in hydra.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Dose-Response Relationship, Drug; Epinephrine; Glutamic Acid; Glycine; Hydra; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Receptors, GABA-B; Serotonin | 2008 |
Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Male; N-Methylaspartate; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Phosphorylation; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tibia; Time Factors | 2008 |
CNQX and AMPA inhibit electrical synaptic transmission: a potential interaction between electrical and glutamatergic synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Concanavalin A; Electrical Synapses; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gap Junctions; Leeches; Long-Term Potentiation; Long-Term Synaptic Depression; Mitogens; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission | 2008 |
Noradrenaline triggers muscle tone by amplifying glutamate-driven excitation of somatic motoneurones in anaesthetized rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Electromyography; Isoproterenol; Male; Masseter Muscle; Motor Neurons; Muscle Tonus; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Glutamate; Trigeminal Nuclei; Vasoconstrictor Agents | 2008 |
Electrical synapses between AII amacrine cells: dynamic range and functional consequences of variation in junctional conductance.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amacrine Cells; Animals; Bicuculline; Biophysics; Computer Literacy; Electric Conductivity; Electric Stimulation; Electrical Synapses; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine Agents; In Vitro Techniques; Models, Neurological; Patch-Clamp Techniques; Rats; Retina; Strychnine; Time Factors | 2008 |
Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biotinylation; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Endocytosis; Ephrin-B2; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphorylation; Protein Transport; Rats; Rats, Wistar; Receptors, AMPA; Serine; Signal Transduction; Synapses; Synaptic Transmission; Transfection | 2008 |
Blocking glutamate receptors in the waist area of the parabrachial nucleus decreases taste reactivity behaviors in conscious rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Male; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Taste | 2009 |
Alterations of excitatory transmission in the lateral amygdala during expression and extinction of fear memory.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amygdala; Animals; Behavior, Animal; Cycloserine; Electric Stimulation; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Fear; In Vitro Techniques; Male; Membrane Potentials; Memory; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission | 2010 |
Bidirectional synaptic plasticity in response to single or paired pulse activation of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
AFM observation of single, functioning ionotropic glutamate receptors reconstituted in lipid bilayers.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western; Electrophysiology; Insecta; Lipid Bilayers; Mice; Microscopy, Atomic Force; Models, Molecular; Receptors, AMPA; Receptors, Glutamate | 2010 |
Stimulation of lateral hypothalamic AMPA receptors may induce feeding in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Food Deprivation; Hypothalamic Area, Lateral; Injections; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Stereoisomerism; Stimulation, Chemical | 2010 |
Plasticity of synaptic GluN receptors is required for the Src-dependent induction of long-term potentiation at CA3-CA1 synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; Indoles; Long-Term Potentiation; Male; Membrane Potentials; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; src-Family Kinases; Sulfonamides; Synapses | 2011 |
Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Endocytosis; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Membrane Potentials; Microscopy, Confocal; N-Methylaspartate; Nedd4 Ubiquitin Protein Ligases; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA Interference; Transfection; Ubiquitin-Protein Ligases; Ubiquitination; Valine | 2010 |
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Anterior Thalamic Nuclei; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Neuropeptides; Neurotransmitter Agents; Patch-Clamp Techniques; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Statistics, Nonparametric; Synaptic Transmission; Valine | 2011 |
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression; Genes, Reporter; Glutamic Acid; Luciferases; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; NFATC Transcription Factors; Nifedipine; Potassium; Progesterone; Rats; Rats, Sprague-Dawley | 2011 |
Blockade of the NMDA and AMPA/kainate receptors in the dorsal raphe nucleus prevents the 5-HT₃ receptor agonist m-chlorophenylbiguanide-induced suppression of REM sleep in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biguanides; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Sleep; Sleep Deprivation; Sleep, REM | 2011 |
A continuous high frequency stimulation of the subthalamic nucleus determines a suppression of excitatory synaptic transmission in nigral dopaminergic neurons recorded in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Bicuculline; Biophysics; Dopaminergic Neurons; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; In Vitro Techniques; Neural Pathways; Rats; Rats, Wistar; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission | 2012 |
Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Patch-Clamp Techniques; Piperazines; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2012 |
Burst firing in gonadotrophin-releasing hormone neurones does not require ionotrophic GABA or glutamate receptor activation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Male; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Organ Culture Techniques; Receptors, GABA-A; Receptors, Ionotropic Glutamate; Synaptic Potentials; Synaptic Transmission | 2012 |
AMPA receptor mediated behavioral plasticity in the isolated rat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Learning; Learning Disabilities; Neuronal Plasticity; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spinal Cord | 2013 |
Seipin regulates excitatory synaptic transmission in cortical neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biotinylation; Brain; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Gene Expression Regulation; GTP-Binding Protein gamma Subunits; Heterotrimeric GTP-Binding Proteins; Immunoprecipitation; Lipodystrophy, Congenital Generalized; Mice; Microscopy, Electron, Transmission; Mutation, Missense; Neurons; Patch-Clamp Techniques; Receptors, AMPA; RNA, Small Interfering; Synapses; Synaptic Transmission; Synaptophysin; Synaptosomes | 2013 |
Adenosine A1 and dopamine d1 receptor regulation of AMPA receptor phosphorylation and cocaine-seeking behavior.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Cocaine; Dopamine Agonists; Drug Interactions; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Gene Transfer Techniques; Male; Microinjections; Nucleus Accumbens; Phosphorylation; Purinergic P1 Receptor Agonists; Pyrazoles; Pyrimidines; Rats; Receptor, Adenosine A1; Receptors, AMPA; Receptors, Dopamine D1; Self Administration | 2013 |
Superoxide anions in paraventricular nucleus modulate adipose afferent reflex and sympathetic activity in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Adipose Tissue, White; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Capsaicin; Cyclic N-Oxides; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reflex; Spin Labels; Superoxide Dismutase; Superoxides; Sympathetic Nervous System | 2013 |
Imbalance of Ca2+ and K+ fluxes in C6 glioma cells after PDT measured with scanning ion-selective electrode technique.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Death; Cell Line, Tumor; Electrophysiology; Glioma; Hematoporphyrin Derivative; Humans; Ion-Selective Electrodes; Photochemotherapy; Potassium; Rats; Receptors, AMPA | 2014 |
Computation of standard binding free energies of polar and charged ligands to the glutamate receptor GluA2.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Algorithms; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acids; Binding Sites; Entropy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Quinoxalines; Receptors, Ionotropic Glutamate; Rotation; Static Electricity; Thermodynamics | 2014 |
Glutaric acid-mediated apoptosis in primary striatal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Caspase 3; Cells, Cultured; Corpus Striatum; Glutarates; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Up-Regulation | 2014 |
Functional Maturation of GABA Synapses During Postnatal Development of the Monkey Dorsolateral Prefrontal Cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Lysine; Macaca mulatta; Models, Neurological; Neurons; omega-Agatoxin IVA; Prefrontal Cortex; Pyridazines; Synapses | 2015 |
α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptor activation protects against phencyclidine-induced caspase-3 activity by activating voltage-gated calcium channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Calcium Channels, L-Type; Caspase 3; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Agents; In Vitro Techniques; Organ Culture Techniques; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Signal Transduction; Time Factors | 2014 |
Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; AIDS-Associated Nephropathy; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Corpus Striatum; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Membrane Potentials; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Morphine; N-Methylaspartate; Primary Cell Culture; Receptors, Opioid, mu; Ryanodine; Sodium; Synapses; tat Gene Products, Human Immunodeficiency Virus | 2014 |
Chronic GABAergic blockade in the spinal cord in vivo induces motor alterations and neurodegeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Bicuculline; Dizocilpine Maleate; Drug Interactions; GABA Antagonists; Gait; Male; Motor Activity; Motor Neurons; Muscle Hypotonia; Nerve Degeneration; Rats; Receptors, Glycine; Spinal Cord; Strychnine | 2017 |
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclin-Dependent Kinase 5; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuronal Plasticity; Neurons; Phosphopyruvate Hydratase; Piperidines; Pyridazines; Sensory Deprivation; Visual Cortex; Visual Pathways | 2018 |
Conveyance of cortical pacing for parkinsonian tremor-like hyperkinetic behavior by subthalamic dysrhythmia.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; Glutamic Acid; Humans; Hyperkinesis; Male; Membrane Potentials; Mice, Inbred C57BL; Motor Cortex; Muscle, Skeletal; Optogenetics; Parkinson Disease, Secondary; Rats; Rats, Wistar; Subthalamic Nucleus; Synapses; Synaptic Transmission; Tremor | 2021 |
L-4-Fluorophenylglycine produces antidepressant-like effects and enhances resilience to stress in mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport Systems, Neutral; Animals; Antidepressive Agents; Depression; Hippocampus; Mammals; Mice; Mice, Inbred C57BL; Serine; Sirolimus; Stress, Psychological; TOR Serine-Threonine Kinases | 2022 |
[Regulation of AMPA receptor on propofol induced hippocampal mitochondrial injury in neonatal rats].
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Hippocampus; Propofol; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 2023 |