alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and 6-(1h-imidazol-1-yl)-7-nitro-2,3(1h,4h)-quinoxalinedione

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with 6-(1h-imidazol-1-yl)-7-nitro-2,3(1h,4h)-quinoxalinedione in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohmori, J; Okada, M; Sakamoto, S; Shimizu-Sasamata, M1
Kohara, A; Okada, M; Yamaguchi, T1
Ohno, K; Okada, M; Sakamoto, S; Tsutsumi, R; Yamaguchi, T1
Bleuel, Z; Clifford, MM; Ellis, GJ; Humbel, U; Klingelschmidt, A; Messer, J; Mutel, V; Richards, JG; Trube, G1
Nakamura, K; Shirane, M1
Bohme, GA; Boireau, A; Damour, D; Debono, MW; Genevois-Borella, A; Imperato, A; Jimonet, P; Mignani, S; Pratt, J; Randle, JC; Ribeill, Y; Stutzmann, JM; Vuilhorgne, M1

Other Studies

6 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and 6-(1h-imidazol-1-yl)-7-nitro-2,3(1h,4h)-quinoxalinedione

ArticleYear
Novel AMPA receptor antagonists: synthesis and structure-activity relationships of 1-hydroxy-7-(1H-imidazol-1-yl)-6-nitro-2,3(1H,4H)- quinoxalinedione and related compounds.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Excitatory Amino Acid Antagonists; Hydroxylation; Imidazoles; Molecular Structure; Quinoxalines; Rats; Receptors, AMPA; Structure-Activity Relationship; Tritium

1996
Characterization of YM90K, a selective and potent antagonist of AMPA receptors, in rat cortical mRNA-injected Xenopus oocytes.
    European journal of pharmacology, 1996, Aug-15, Volume: 309, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Drug; Kainic Acid; Male; Oocytes; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA

1996
The AMPA-receptor antagonist YM90K reduces AMPA receptor-mediated excitotoxicity in rat hippocampal cultures.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cells, Cultured; Diuretics; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Kainic Acid; Neurons; Neuroprotective Agents; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Sodium Chloride Symporter Inhibitors

1998
Binding characteristics of a potent AMPA receptor antagonist [3H]Ro 48-8587 in rat brain.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; In Situ Hybridization; Kainic Acid; Kinetics; Male; N-Methylaspartate; Quinazolines; Quinoxalines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; RNA, Messenger; Tritium

1998
Group II metabotropic glutamate receptors are a common target of N-anisoyl-GABA and 1S,3R-ACPD in enhancing ACh release in the prefrontal cortex of freely moving SHRSP.
    Neuropharmacology, 2000, Mar-03, Volume: 39, Issue:5

    Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Anisoles; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indans; Male; Microdialysis; Perfusion; Prefrontal Cortex; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, AMPA; Receptors, Metabotropic Glutamate; Thalamic Nuclei; Wakefulness

2000
4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives: highly potent and selective AMPA receptors antagonists with in vivo activity.
    Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Inhibitory Concentration 50; Isoquinolines; Mice; Mice, Inbred DBA; Pyrazines; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tetrazoles; Urea

2000