Compounds > alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and 4-bromohomoibotenic acid, (rs)-isomer

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with 4-bromohomoibotenic acid, (rs)-isomer in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Didriksen, M; Ebert, B; Engesgaard, A; Frølund, B; Jaroszewski, JW; Krogsgaard-Larsen, P; Matzen, L1
Bräuner-Osborne, H; Brehm, L; Christensen, IT; Didriksen, M; Ebert, B; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U; Søby, KK1
Bjerrum, EJ; Bräuner-Osborne, H; Greenwood, JR; Kristensen, AS; Liljefors, T; Madsen, U; Nielsen, B; Pickering, DS; Schousboe, A1
England, PM; Fleming, JJ1

Other Studies

4 other study(ies) available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and 4-bromohomoibotenic acid, (rs)-isomer

ArticleYear
AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
    Journal of medicinal chemistry, 1997, Feb-14, Volume: 40, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Glutamic Acid; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Thiazoles

1997
Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alanine; Animals; Anticonvulsants; Brain; Calcium Chloride; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoxazoles; Male; Mice; Molecular Conformation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Stereoisomerism

1998
Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO).
    Journal of medicinal chemistry, 2003, May-22, Volume: 46, Issue:11

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; In Vitro Techniques; Isoxazoles; Mice; Models, Molecular; Neurons; Oocytes; Propionates; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis

2003
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
    Bioorganic & medicinal chemistry, 2010, Feb-15, Volume: 18, Issue:4

    Topics: Allosteric Regulation; Animals; Binding Sites; Ligands; Receptors, AMPA

2010