alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid and aspartic acid

alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid has been researched along with aspartic acid in 2 studies

Compound Research Comparison

Studies (alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid)	Trials (alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid)	Recent Studies (post-2010) (alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid)	Studies (aspartic acid)	Trials (aspartic acid)	Recent Studies (post-2010) (aspartic acid)
7	0	0	23,005	417	4,018

Protein Interaction Comparison

Protein	Taxonomy	aspartic acid (IC50)
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	1.638
Excitatory amino acid transporter 1	Homo sapiens (human)	90.1265
Excitatory amino acid transporter 2	Homo sapiens (human)	11
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	1.638
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	1.638
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	1.638
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	1.638
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	1.638
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	1.638

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW	1
Bräuner-Osborne, H; Ebert, B; Krogsgaard-Larsen, P; Nakanishi, S; Sekiyama, N; Skjaerbaek, N; Sløk, FA	1

Other Studies

2 other study(ies) available for alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid and aspartic acid

Article	Year
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists. Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8 Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1992
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16 Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Magnetic Resonance Spectroscopy; Molecular Structure; N-Methylaspartate; Receptors, Metabotropic Glutamate	1996

Article

Year

Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists.

Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8

Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1992

A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid.

Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16

Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Magnetic Resonance Spectroscopy; Molecular Structure; N-Methylaspartate; Receptors, Metabotropic Glutamate

1996