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alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 3 studies

Compound Research Comparison

Studies
(alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid)
Trials
(alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid)
Recent Studies (post-2010)
(alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid)
Studies
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Trials
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
7002403

Protein Interaction Comparison

ProteinTaxonomyalpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid (IC50)alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50)
Glutamate receptor 1Rattus norvegicus (Norway rat)0.1049
Glutamate receptor 2Rattus norvegicus (Norway rat)0.1049
Glutamate receptor 3Rattus norvegicus (Norway rat)0.1049
Glutamate receptor 4Rattus norvegicus (Norway rat)0.1049

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U1
Brehm, L; Ebert, B; Frydenvang, K; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U1
Bräuner-Osborne, H; Ebert, B; Krogsgaard-Larsen, P; Nakanishi, S; Sekiyama, N; Skjaerbaek, N; Sløk, FA1

Other Studies

3 other study(ies) available for alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

ArticleYear
Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Acetates; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; Glycine; Hydrogen Bonding; Isoxazoles; Ligands; Molecular Conformation; Molecular Structure; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Structure-Activity Relationship; Thermodynamics

1994
N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Acetates; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Electrophysiology; Excitatory Amino Acid Agonists; Hydrogen Bonding; In Vitro Techniques; Isoxazoles; Molecular Structure; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism

1996
A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid.
    Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Magnetic Resonance Spectroscopy; Molecular Structure; N-Methylaspartate; Receptors, Metabotropic Glutamate

1996