alpha-(4-pyridyl-1-oxide)-n-tert-butylnitrone and imidazole

alpha-(4-pyridyl-1-oxide)-n-tert-butylnitrone has been researched along with imidazole* in 1 studies

Other Studies

1 other study(ies) available for alpha-(4-pyridyl-1-oxide)-n-tert-butylnitrone and imidazole

Article	Year
Peroxynitrite reacts with biological nitrogen-containing cyclic molecules by a radical pathway, as demonstrated by ultraweak luminescence coupled with ESR technique. Biochemical and biophysical research communications, 1999, Jun-07, Volume: 259, Issue:2 Ultraweak luminescence (uwCL) was coupled with electron spin resonance to study the reactions of 3 heterocyclic compounds (tryptophan, serotonin and imidazole) with peroxynitrite at pH 8.7. Tryptophan and serotonin reacted with emission of a flash peak of light (5 s) followed by a long-living light emission of +/- 80 s. Addition of the spin trap 4-POBN at different intervals, after the beginning of reaction revealed that a short-living free radical was produced in the case of serotonin and imidazole, but that with tryptophan, the initial radical rearranged into a relatively long-living radical, which was still formed when 4-POBN was added after 55 s (decreasing phase of uwCL). Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Heterocyclic Compounds; Imidazoles; Kinetics; Luminescent Measurements; Molecular Structure; Nitrates; Nitrogen Oxides; Pyridines; Serotonin; Spin Labels; Tryptophan	1999

Article

Year

Peroxynitrite reacts with biological nitrogen-containing cyclic molecules by a radical pathway, as demonstrated by ultraweak luminescence coupled with ESR technique.

Biochemical and biophysical research communications, 1999, Jun-07, Volume: 259, Issue:2

Ultraweak luminescence (uwCL) was coupled with electron spin resonance to study the reactions of 3 heterocyclic compounds (tryptophan, serotonin and imidazole) with peroxynitrite at pH 8.7. Tryptophan and serotonin reacted with emission of a flash peak of light (5 s) followed by a long-living light emission of +/- 80 s. Addition of the spin trap 4-POBN at different intervals, after the beginning of reaction revealed that a short-living free radical was produced in the case of serotonin and imidazole, but that with tryptophan, the initial radical rearranged into a relatively long-living radical, which was still formed when 4-POBN was added after 55 s (decreasing phase of uwCL).

Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Heterocyclic Compounds; Imidazoles; Kinetics; Luminescent Measurements; Molecular Structure; Nitrates; Nitrogen Oxides; Pyridines; Serotonin; Spin Labels; Tryptophan

1999