alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and remoxipride

alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been researched along with remoxipride in 3 studies

Compound Research Comparison

Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)	Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)	Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)	Studies (remoxipride)	Trials (remoxipride)	Recent Studies (post-2010) (remoxipride)
90	1	2	272	65	21

Protein Interaction Comparison

Protein	Taxonomy	remoxipride (IC50)
Bile salt export pump	Homo sapiens (human)	10
D(2) dopamine receptor	Homo sapiens (human)	0.4406
D(4) dopamine receptor	Homo sapiens (human)	3.872
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	1.57

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	2 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gudelsky, GA; Nash, JF	1
Largent, BL; Snyder, SH	1
Monnet, FP	1

Reviews

2 review(s) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and remoxipride

Article	Year
Receptor mechanisms in antipsychotic drug action: focus on sigma receptors. The Journal of neuropsychiatry and clinical neurosciences, 1989,Winter, Volume: 1, Issue:1 Topics: Antipsychotic Agents; Benzamides; Carbazoles; Carbolines; Drug Design; Female; Humans; Isoquinolines; Male; Piperazines; Pyridines; Pyrimidines; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, Serotonin; Receptors, sigma; Remoxipride; Schizophrenia; Spiro Compounds	1989
[Involvement of sigma receptors in schizophrenic syndromes. Pathophysiological approach]. Presse medicale (Paris, France : 1983), 1993, Feb-13, Volume: 22, Issue:5 Topics: Antipsychotic Agents; Carbazoles; Hippocampus; Humans; Piperidines; Psychotropic Drugs; Pyrimidines; Receptors, sigma; Remoxipride; Schizophrenia; Thalamus	1993

Article

Year

Receptor mechanisms in antipsychotic drug action: focus on sigma receptors.

The Journal of neuropsychiatry and clinical neurosciences, 1989,Winter, Volume: 1, Issue:1

Topics: Antipsychotic Agents; Benzamides; Carbazoles; Carbolines; Drug Design; Female; Humans; Isoquinolines; Male; Piperazines; Pyridines; Pyrimidines; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, Serotonin; Receptors, sigma; Remoxipride; Schizophrenia; Spiro Compounds

1989

[Involvement of sigma receptors in schizophrenic syndromes. Pathophysiological approach].

Presse medicale (Paris, France : 1983), 1993, Feb-13, Volume: 22, Issue:5

Topics: Antipsychotic Agents; Carbazoles; Hippocampus; Humans; Piperidines; Psychotropic Drugs; Pyrimidines; Receptors, sigma; Remoxipride; Schizophrenia; Thalamus

1993

Other Studies

1 other study(ies) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and remoxipride

Article	Year
Neuroendocrinological and neurochemical effects of sigma ligands. Neuropharmacology, 1992, Volume: 31, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Brain; Carbolines; Corticosterone; Dopamine; Dose-Response Relationship, Drug; Male; Median Eminence; Neurons; Prolactin; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Remoxipride; Spiro Compounds; Tyrosine 3-Monooxygenase	1992

Article

Year

Neuroendocrinological and neurochemical effects of sigma ligands.

Neuropharmacology, 1992, Volume: 31, Issue:2

Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Brain; Carbolines; Corticosterone; Dopamine; Dose-Response Relationship, Drug; Male; Median Eminence; Neurons; Prolactin; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Remoxipride; Spiro Compounds; Tyrosine 3-Monooxygenase

1992