alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been researched along with phencyclidine in 10 studies
| Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Studies (phencyclidine) | Trials (phencyclidine) | Recent Studies (post-2010) (phencyclidine) |
|---|---|---|---|---|---|
| 90 | 1 | 2 | 28,294 | 387 | 7,796 |
| Protein | Taxonomy | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50) | phencyclidine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1299 | |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | 0.091 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.5563 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.205 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 1.2589 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1299 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.53 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1299 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, BG; Kimes, AS; London, ED; Scheffel, U; Wilson, AA | 1 |
| Harro, J; Lang, A; Soosaar, A; Vasar, E | 1 |
| Bush, LG; Gibb, JW; Hanson, GR; Midgley, LP | 1 |
| Hudzik, TJ; Slifer, BL | 1 |
| Cook, L; Steinfels, GF; Tam, SW | 1 |
| Araki, H; Ogawa, S; Okuyama, S; Otomo, S; Tsuchida, K | 1 |
| Araki, H; Ogawa, S; Okuyama, S; Otomo, S | 1 |
| Maurice, T; Nabeshima, T; Parish, DW; Privat, A; Su, TP | 1 |
| Chaki, S; Imagawa, Y; Muramatsu, M; Okuyama, S; Otomo, S; Tanaka, M | 1 |
| Kamei, H; Kameyama, T; Nabeshima, T | 1 |
10 other study(ies) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and phencyclidine
| Article | Year |
|---|---|
Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Guanidines; Guinea Pigs; Iodobenzenes; Male; Mice; Receptors, sigma; Tissue Distribution | 1992 |
The involvement of sigma and phencyclidine receptors in the action of antipsychotic drugs.
Topics: Animals; Brain; Clozapine; Ligands; Male; Mice; Motor Activity; Phencyclidine; Psychotropic Drugs; Pyrimidines; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1992 |
Characterization of phencyclidine-induced effects on neuropeptide Y systems in the rat caudate-putamen.
Topics: 4-Aminobutyrate Transaminase; Adrenergic beta-Antagonists; Aminocaproates; Aminooxyacetic Acid; Animals; Benzazepines; Carbazoles; Corpus Striatum; Dioxanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Idazoxan; Male; Naloxone; Neuropeptide Y; Phencyclidine; Prazosin; Psychotropic Drugs; Putamen; Pyrimidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Time Factors; Vigabatrin | 1992 |
Interaction of sigma and PCP-like drugs on operant behaviors in the rat.
Topics: Animals; Conditioning, Operant; Dextroamphetamine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Pentazocine; Phenazocine; Phencyclidine; Psychotropic Drugs; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement Schedule | 1992 |
Electrophysiological effects of selective sigma-receptor agonists, antagonists, and the selective phencyclidine receptor agonist MK-801 on midbrain dopamine neurons.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbazoles; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dopamine Agents; Male; Neurons; Pentazocine; Phencyclidine; Piperidines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Substantia Nigra | 1989 |
The sigma-selective ligand NE-100 attenuates the effect of phencyclidine in a rat diving model.
Topics: Animals; Anisoles; Carbazoles; Diving; Male; Motor Activity; Phencyclidine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma | 1995 |
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction.
Topics: Animals; Anisoles; Anti-Anxiety Agents; Cognition Disorders; Drug Interactions; Ligands; Male; Phencyclidine; Physical Exertion; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma; Ritanserin; Swimming | 1994 |
PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Cholinergic Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Maze Learning; Memory; Memory, Short-Term; Mice; Morpholines; Phencyclidine; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma | 1994 |
FH-510, a potent and selective ligand for rat brain sigma recognition sites.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Carbazoles; Dopamine; Haloperidol; Male; Mice; Phenazocine; Phencyclidine; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma; Stereotyped Behavior | 1993 |
(+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress through the activation of phenytoin-regulated sigma 1 sites.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Phenazocine; Phencyclidine; Phenytoin; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stress, Physiological | 1996 |