Page last updated: 2024-09-02

alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride

alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been researched along with n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride in 4 studies

Compound Research Comparison

Studies
(alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)
Trials
(alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)
Recent Studies (post-2010)
(alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)
Studies
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Trials
(n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
Recent Studies (post-2010) (n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride)
901298029
9012502

Protein Interaction Comparison

ProteinTaxonomyalpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50)n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride (IC50)
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)6.46

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Araki, H; Ogawa, S; Okuyama, S; Otomo, S; Tsuchida, K1
Araki, H; Ogawa, S; Okuyama, S; Otomo, S1
Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Noda, Y1
Chaki, S; Hatayama, K; Kawashima, Y; Nakazato, A; Ohta, K; Okuyama, S; Sekiguchi, Y1

Other Studies

4 other study(ies) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride

ArticleYear
The sigma-selective ligand NE-100 attenuates the effect of phencyclidine in a rat diving model.
    General pharmacology, 1995, Volume: 26, Issue:1

    Topics: Animals; Anisoles; Carbazoles; Diving; Male; Motor Activity; Phencyclidine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma

1995
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction.
    European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2

    Topics: Animals; Anisoles; Anti-Anxiety Agents; Cognition Disorders; Drug Interactions; Ligands; Male; Phencyclidine; Physical Exertion; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma; Ritanserin; Swimming

1994
In vivo functional interaction between phencyclidine binding sites and sigma receptors to produce head-weaving behavior in rats.
    European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3

    Topics: Animals; Anisoles; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Guanidines; Male; Phenazocine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, sigma

1996
Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs.
    Journal of medicinal chemistry, 1999, Mar-25, Volume: 42, Issue:6

    Topics: Animals; Anisoles; Antipsychotic Agents; Brain; Drug Design; Drug Evaluation, Preclinical; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Propylamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, sigma; Stereotyped Behavior; Structure-Activity Relationship

1999