Page last updated: 2024-09-02
alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and ketanserin
alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been researched along with ketanserin in 1 studies
Compound Research Comparison
Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Studies (ketanserin) | Trials (ketanserin) | Recent Studies (post-2010) (ketanserin) |
---|---|---|---|---|---|
90 | 1 | 2 | 3,094 | 335 | 283 |
Protein Interaction Comparison
Protein | Taxonomy | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50) | ketanserin (IC50) |
---|---|---|---|
5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0016 | |
5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0021 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.015 | |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.015 | |
5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.265 | |
5-hydroxytryptamine receptor 1B | Homo sapiens (human) | 6.5 | |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0184 | |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0027 | |
5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0016 | |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.29 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.015 | |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 1.8 | |
Synaptic vesicular amine transporter | Homo sapiens (human) | 0.18 | |
Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.001 |
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD | 1 |
Other Studies
1 other study(ies) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and ketanserin
Article | Year |
---|---|
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |