alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and atropine

alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been researched along with atropine in 2 studies

Compound Research Comparison

Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)	Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)	Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)	Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)
90	1	2	26,711	1,259	1,697

Protein Interaction Comparison

Protein	Taxonomy	atropine (IC50)
cystic fibrosis transmembrane conductance regulator	Homo sapiens (human)	21.41
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	1.012
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	0.0067
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	0.0007
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	0.001
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	0.001
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	0.001
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	0.001
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	0.0009
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	0.001
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	0.0015
Muscarinic acetylcholine receptor M3	Homo sapiens (human)	0.0021
Alpha-1D adrenergic receptor	Homo sapiens (human)	1.354
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	1.012

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD	1
Chariot, J; Fu-Cheng, X; Rozé, C; Souli, A	1

Other Studies

2 other study(ies) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and atropine

Article	Year
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors. Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes	1999
Antisecretory effect of peptide YY through neural receptors in the rat jejunum in vitro. Peptides, 1999, Volume: 20, Issue:8 Topics: Animals; Atropine; Haloperidol; Hexamethonium; Idazoxan; In Vitro Techniques; Jejunum; Male; Peptide YY; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin	1999

Article

Year

Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.

Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes

1999

Antisecretory effect of peptide YY through neural receptors in the rat jejunum in vitro.

Peptides, 1999, Volume: 20, Issue:8

Topics: Animals; Atropine; Haloperidol; Hexamethonium; Idazoxan; In Vitro Techniques; Jejunum; Male; Peptide YY; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin

1999