alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been researched along with amphetamine in 3 studies
| Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Studies (amphetamine) | Trials (amphetamine) | Recent Studies (post-2010) (amphetamine) |
|---|---|---|---|---|---|
| 90 | 1 | 2 | 13,071 | 329 | 1,977 |
| Protein | Taxonomy | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50) | amphetamine (IC50) |
|---|---|---|---|
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | 0.96 | |
| Cytochrome P450 2A6 | Homo sapiens (human) | 3.5 | |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | 2.85 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.96 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.96 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haracz, JL; Rebec, GV; Wang, Z | 1 |
| Baucutt, L; Beer, M; Bristow, LJ; Hutson, PH; Middlemiss, DN; Noble, A; Thorn, L; Tricklebank, MD | 1 |
| Berger, SP; Brudney, EG; Johnson, SW; Meshul, CK; Paquette, MA; Putterman, DB | 1 |
3 other study(ies) available for alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol and amphetamine
| Article | Year |
|---|---|
BMY-14802, a sigma ligand and potential antipsychotic drug, reverses amphetamine-induced changes in neostriatal single-unit activity in freely moving rats.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior, Animal; Corpus Striatum; Electrophysiology; Ligands; Male; Motor Activity; Neurons; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1992 |
Behavioural and biochemical evidence of the interaction of the putative antipsychotic agent, BMY 14802 with the 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Discrimination Learning; Drug Interactions; Hyperkinesis; Male; Mice; Pyrimidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Rectum; Tetrahydronaphthalenes; Tranquilizing Agents | 1991 |
Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias.
Topics: Adrenergic Agents; Amphetamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Dextromethorphan; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Ligands; Male; N-Methylaspartate; Neurotoxicity Syndromes; Oxidopamine; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |