alpha-(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol has been researched along with halofantrine in 3 studies
| Studies (alpha-(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol) | Trials (alpha-(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol) | Recent Studies (post-2010) (alpha-(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol) | Studies (halofantrine) | Trials (halofantrine) | Recent Studies (post-2010) (halofantrine) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 486 | 68 | 49 |
| Protein | Taxonomy | alpha-(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol (IC50) | halofantrine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 1.9 | |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 1.9 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.1622 | |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 1.9 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 1.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowdre, JH; Desjardins, RE; Milhous, WK; Oduola, AM; Weatherly, NF | 1 |
| Gerena, L; Karle, JM; Milhous, WK; Olmeda, R | 1 |
| Bhattacharjee, AK; Karle, JM | 1 |
3 other study(ies) available for alpha-(2-piperidyl)-3,6-bis(trifluoromethyl)-9-phenanthrenemethanol and halofantrine
| Article | Year |
|---|---|
Plasmodium falciparum: induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro.
Topics: Animals; Antimalarials; Butylated Hydroxytoluene; Chemical Phenomena; Chemistry; Culture Media; Drug Resistance; Isoenzymes; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinolines | 1988 |
Plasmodium falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Pyridines; Quinolines; Stereoisomerism; Structure-Activity Relationship | 1993 |
Functional correlation of molecular electronic properties with potency of synthetic carbinolamine antimalarial agents.
Topics: Antimalarials; Mefloquine; Models, Molecular; Molecular Conformation; Phenanthrenes; Pyridines; Quinolines; Static Electricity; Structure-Activity Relationship | 1998 |