Page last updated: 2024-09-05

alnespirone and spiperone

alnespirone has been researched along with spiperone in 2 studies

Compound Research Comparison

Studies
(alnespirone)
Trials
(alnespirone)
Recent Studies (post-2010)
(alnespirone)
Studies
(spiperone)
Trials
(spiperone)
Recent Studies (post-2010) (spiperone)
28002,9441385

Protein Interaction Comparison

ProteinTaxonomyalnespirone (IC50)spiperone (IC50)
Bile salt export pumpHomo sapiens (human)10
D(2) dopamine receptorHomo sapiens (human)0.0008
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.097
D(4) dopamine receptorHomo sapiens (human)0.0005
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.097
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.097
D(3) dopamine receptorHomo sapiens (human)0.0635
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.097
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0001
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.955

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gustafson, M; Levy, AD; Li, Q; Van de Kar, LD1
Brownfield, MS; Levy, AD; Li, Q; Van de Kar, LD1

Other Studies

2 other study(ies) available for alnespirone and spiperone

ArticleYear
Neuroendocrine profile of the potential anxiolytic drug S-20499.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Blood Pressure; Corticosterone; Dopamine Agonists; Dose-Response Relationship, Drug; Heart Rate; Injections, Intraperitoneal; Male; Neurosecretory Systems; Pindolol; Prolactin; Rats; Rats, Sprague-Dawley; Renin; Serotonin Receptor Agonists; Spiperone; Spiro Compounds; Stereoisomerism

1995
A comparison of the oxytocin and vasopressin responses to the 5-HT1A agonist and potential anxiolytic drug alnespirone (S-20499).
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Oxytocin; Pindolol; Rats; Serotonin Receptor Agonists; Spiperone; Spiro Compounds; Vasopressins

1998