alnespirone has been researched along with spiperone in 2 studies
| Studies (alnespirone) | Trials (alnespirone) | Recent Studies (post-2010) (alnespirone) | Studies (spiperone) | Trials (spiperone) | Recent Studies (post-2010) (spiperone) |
|---|---|---|---|---|---|
| 28 | 0 | 0 | 2,944 | 13 | 85 |
| Protein | Taxonomy | alnespirone (IC50) | spiperone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0008 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.097 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0635 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0001 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gustafson, M; Levy, AD; Li, Q; Van de Kar, LD | 1 |
| Brownfield, MS; Levy, AD; Li, Q; Van de Kar, LD | 1 |
2 other study(ies) available for alnespirone and spiperone
| Article | Year |
|---|---|
Neuroendocrine profile of the potential anxiolytic drug S-20499.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Blood Pressure; Corticosterone; Dopamine Agonists; Dose-Response Relationship, Drug; Heart Rate; Injections, Intraperitoneal; Male; Neurosecretory Systems; Pindolol; Prolactin; Rats; Rats, Sprague-Dawley; Renin; Serotonin Receptor Agonists; Spiperone; Spiro Compounds; Stereoisomerism | 1995 |
A comparison of the oxytocin and vasopressin responses to the 5-HT1A agonist and potential anxiolytic drug alnespirone (S-20499).
Topics: Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Oxytocin; Pindolol; Rats; Serotonin Receptor Agonists; Spiperone; Spiro Compounds; Vasopressins | 1998 |