alnespirone has been researched along with ipsapirone in 2 studies
| Studies (alnespirone) | Trials (alnespirone) | Recent Studies (post-2010) (alnespirone) | Studies (ipsapirone) | Trials (ipsapirone) | Recent Studies (post-2010) (ipsapirone) |
|---|---|---|---|---|---|
| 28 | 0 | 0 | 373 | 58 | 14 |
| Protein | Taxonomy | alnespirone (IC50) | ipsapirone (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 10 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 10 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 1 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0082 | |
| D(4) dopamine receptor | Homo sapiens (human) | 1.8 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.5 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 10 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.5 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.5 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.2 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Boer, SF; Koolhaas, JM; Lesourd, M; Mocaer, E | 1 |
| Beaufour, C; Evrard, A; Fabre, V; Hamon, M; Hanoun, N; Lanfumey, L; Lesch, KP; Martres, MP; Murphy, DL; Rioux, A | 1 |
2 other study(ies) available for alnespirone and ipsapirone
| Article | Year |
|---|---|
Selective antiaggressive effects of alnespirone in resident-intruder test are mediated via 5-hydroxytryptamine1A receptors: A comparative pharmacological study with 8-hydroxy-2-dipropylaminotetralin, ipsapirone, buspirone, eltoprazine, and WAY-100635.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Buspirone; Male; Piperazines; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds | 1999 |
Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter.
Topics: Animals; Autoreceptors; Binding, Competitive; Brain Chemistry; Carrier Proteins; Citalopram; Dipeptides; Down-Regulation; Gene Expression; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Oxadiazoles; Piperazines; Pyridines; Pyrimidines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Spiro Compounds; Substantia Nigra; Sulfur Radioisotopes; Synaptic Transmission; Tritium | 2000 |