alnespirone has been researched along with buspirone in 5 studies
Studies (alnespirone) | Trials (alnespirone) | Recent Studies (post-2010) (alnespirone) | Studies (buspirone) | Trials (buspirone) | Recent Studies (post-2010) (buspirone) |
---|---|---|---|---|---|
28 | 0 | 0 | 2,096 | 351 | 382 |
Protein | Taxonomy | alnespirone (IC50) | buspirone (IC50) |
---|---|---|---|
5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.025 | |
5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 1.75 | |
Angiotensin-converting enzyme | Homo sapiens (human) | 0.024 | |
D(2) dopamine receptor | Homo sapiens (human) | 0.323 | |
5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 2.125 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
D | Rattus norvegicus (Norway rat) | 0.12 | |
D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0266 | |
D(2) dopamine receptor | Bos taurus (cattle) | 4 | |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.077 | |
D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.286 | |
5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.016 | |
D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 2.125 | |
D(3) dopamine receptor | Homo sapiens (human) | 0.044 | |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.75 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.2055 | |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.9811 | |
Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.025 | |
Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.7 | |
Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.2666 | |
Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.03 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (60.00) | 18.2507 |
2000's | 2 (40.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bizot-Espiard, J; Costentin, J; Guardiola, B; Schiavi, P; Simon, P | 1 |
Comoy, E; Lesourd, M; Protais, P | 1 |
de Boer, SF; Koolhaas, JM; Lesourd, M; Mocaer, E | 1 |
Bertaglia, A; Cervo, L; Munoz, C; Samanin, R | 1 |
Astier, B; Bert, L; Chouvet, G; Denoroy, L; Lambás Señas, L; Lesourd, M; Muñoz, C; Renaud, B; Rentero, N; Schmitt, P; Soulière, F; Urbain, N | 1 |
5 other study(ies) available for alnespirone and buspirone
Article | Year |
---|---|
5-HT1A receptor agonists prevent in rats the yawning and penile erections induced by direct dopamine agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Aminoquinolines; Animals; Body Temperature; Buspirone; Chromans; Dopamine Agents; Male; Mice; Penile Erection; Propanolamines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Spiro Compounds; Thiophenes; Yawning | 1992 |
Similar pharmacological properties of 8-OH-DPAT and alnespirone (S 20499) at dopamine receptors: comparison with buspirone.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzazepines; Buspirone; Corpus Striatum; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Mice; Piperazines; Raclopride; Salicylamides; Serotonin; Serotonin Antagonists; Spiro Compounds; Tritium | 1998 |
Selective antiaggressive effects of alnespirone in resident-intruder test are mediated via 5-hydroxytryptamine1A receptors: A comparative pharmacological study with 8-hydroxy-2-dipropylaminotetralin, ipsapirone, buspirone, eltoprazine, and WAY-100635.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Buspirone; Male; Piperazines; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds | 1999 |
Alnespirone and buspirone have anxiolytic-like effects in a conflict procedure in rats by stimulating 5-HT(1A) receptors.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Conditioning, Operant; Conflict, Psychological; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds | 2000 |
In vivo comparison of two 5-HT1A receptors agonists alnespirone (S-20499) and buspirone on locus coeruleus neuronal activity.
Topics: Animals; Buspirone; Clonidine; Electrophysiology; Locus Coeruleus; Male; Microdialysis; Neurons; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Spiro Compounds; Time Factors | 2003 |